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The HIV/AIDS pandemic is increasingly beingacknowledged as a growing governance challenge.As HIV/AIDS hinders economic and social growthby draining poor nations of their children, workersand leaders, it puts pressure on political systemsand democratic governance. This comparative study,covering Botswana, Ghana, Kenya, Mozambique andSouth Africa, considers what these parliaments aredoing about HIV/AIDS. It provides lessons learned anddetailed analysis of the effective use of parliamentaryoversight in national responses to HIV/AIDS.