Arterial Stiffness and Cardiovascular Diseases

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Effects of cilnidipine onsympathetic nervous systemand arterial stiffness inessential hypertensionJeong Bae Park, MD, PhD, FAHASamsung Cheil Hospital, Sungkyunkwan UniversitySchool of Medicine and Samsung Biomedical ResearchInstitute
Vascular function before and after3-month treatmentof cilnidipine or amlodipineVascular function cilnidipine amlodipineBefore 3months Before 3monthsCarotid β 1.46 1.37 1.67 1.39Aorta β 11.1 5.72 * 10.5 7.43 *AI index, % 36 28 * 36 27 *SEVR 158 159 174 169AI response tosalbutamol, %4.1 9.1 4.8 4.7
Page 1 and 2: Arterial Stiffness andCardiovascula
Page 7 and 8: BaselineBoth femoral arteryocclusio
Page 9: • Mechanical stiffness of thePuls
Page 12 and 13: Blood Pressure, mmHgChanges of Bloo
Page 14 and 15: •Systolic BP: SV,aortic stiffness
Page 16: AB100 mmHg 100 mmHg
Page 19 and 20: “Two new epidemics ofcardiovascul
Page 21 and 22: Rate/100,000 populationHospitalizat
Page 23 and 24: Population and Personal Health Care
Page 25: CHF =SystolicDysfunction
Page 28 and 29: What about EF ?1) 25%2) 40%3) 55%4)
Page 30 and 31: ARDS ??NT ProBNP: 6,869 pg/ml(norma
Page 32 and 33: Diastolic heart failureis common!
Page 35 and 36: Ha JW et al. J Am Coll Cardiol 2002
Page 37: Risks Associated With LVH• LVH ma
Page 42 and 43: Role ofAntihypertensiveMedications
Page 44 and 45: Angiotensin II and AT 1 Receptor
Page 48 and 49: Serum norepinephrine change, pg/mlS
Page 50: Arterial stiffness• CV risk• Sy

Arterial Stiffness and Cardiovascular Diseases

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