Arterial Stiffness and Cardiovascular Diseases

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What Is Arterial Stiffness?• Arteries serve a dual role of conductingblood to the peripheral tissues andbuffering the pressure pulsations that area necessary accompaniment ofintermittent ventricular pumping• Loss of this buffering function manifests aselevated pulse pressure, which adds toload on the heart and likely damages thelarge and small vessels as well
• Mechanical stiffness of thePulse featuresvasculature• Cardiac afterload• Pathogenesis of systolic HTNAUG (mm Hg)PressureRT (msec)Time
Page 1 and 2: Arterial Stiffness andCardiovascula
Page 7: BaselineBoth femoral arteryocclusio
Page 12 and 13: Blood Pressure, mmHgChanges of Bloo
Page 14 and 15: •Systolic BP: SV,aortic stiffness
Page 16: AB100 mmHg 100 mmHg
Page 19 and 20: “Two new epidemics ofcardiovascul
Page 21 and 22: Rate/100,000 populationHospitalizat
Page 23 and 24: Population and Personal Health Care
Page 25: CHF =SystolicDysfunction
Page 28 and 29: What about EF ?1) 25%2) 40%3) 55%4)
Page 30 and 31: ARDS ??NT ProBNP: 6,869 pg/ml(norma
Page 32 and 33: Diastolic heart failureis common!
Page 35 and 36: Ha JW et al. J Am Coll Cardiol 2002
Page 37: Risks Associated With LVH• LVH ma
Page 42 and 43: Role ofAntihypertensiveMedications
Page 44 and 45: Angiotensin II and AT 1 Receptor
Page 46 and 47: Effects of cilnidipine onsympatheti
Page 48 and 49: Serum norepinephrine change, pg/mlS
Page 50: Arterial stiffness• CV risk• Sy

Arterial Stiffness and Cardiovascular Diseases

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