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Study on the chemical constituents of the essential oil of the leaves ...

Study on the chemical constituents of the essential oil of the leaves ...

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<str<strong>on</strong>g>Study</str<strong>on</strong>g> <strong>on</strong> <strong>the</strong> <strong>chemical</strong> c<strong>on</strong>stituents <strong>of</strong> <strong>the</strong> <strong>essential</strong> <strong>oil</strong> <strong>of</strong> <strong>the</strong> <strong>leaves</strong> <strong>of</strong> Eucalyptus globulus Labill / Asian Journal <strong>of</strong>Traditi<strong>on</strong>al Medicines, 2009, 4 (4)AFig.8 The MS <strong>of</strong> (-)-globulol in <strong>the</strong> <strong>essential</strong> <strong>oil</strong> <strong>of</strong> Eucalyptus globulus Labill <strong>leaves</strong>BFig.8 The MS <strong>of</strong> (-)-globulol in <strong>the</strong> <strong>essential</strong> <strong>oil</strong> <strong>of</strong> Eucalyptus globulus Labill <strong>leaves</strong>Fig. 5. A. The MS Fig.9 <strong>of</strong> (-)-globulol The MS <strong>of</strong> in (-)-globulol <strong>the</strong> <strong>essential</strong> in <strong>oil</strong> NIST02 <strong>of</strong> Eucalyptus library globulus data <strong>of</strong> Labill <strong>the</strong> GC-MS <strong>leaves</strong>; B. system The MS <strong>of</strong> (-)-globulol in NIST02library data <strong>of</strong> <strong>the</strong> GC-MS systemResults and Discussi<strong>on</strong>C<strong>on</strong>clusi<strong>on</strong> Fig.9 The MS <strong>of</strong> (-)-globulol in NIST02 library [3] data Gray <strong>of</strong> AM, <strong>the</strong> Abdel-Wahab GC-MS system YHA, Flatt PR. The traditi<strong>on</strong>alplant treatment, sambucus nigra (elder), exhibits insulinlikeand insulin-releasingIn <strong>the</strong> The present total i<strong>on</strong> work, chromatogram 47 c<strong>on</strong>stituents <strong>of</strong> <strong>the</strong> <strong>of</strong> <strong>essential</strong> <strong>the</strong> <strong>oil</strong> is displayed in Fig.1. Theacti<strong>on</strong>samountsin vitro.<strong>of</strong> <strong>the</strong>J Nutr, 2000,<strong>essential</strong> <strong>oil</strong> from Eucalyptus globulus Labill grown in 130(1): 15-20.comp<strong>on</strong>ents from <strong>the</strong> volatile <strong>oil</strong> were determinated by <strong>the</strong> peak area normalizati<strong>on</strong> method. This<strong>the</strong> Cangshan Results and mountain Discussi<strong>on</strong> regi<strong>on</strong> in <strong>the</strong> Yunnan Province [4] Ikawati Z, Wahyu<strong>on</strong>o S, Maeyama K. Screening <strong>of</strong>several Ind<strong>on</strong>esian medicinal plants for <strong>the</strong>ir inhibitory<strong>of</strong> China presence were successfully <strong>of</strong> several overlapping identified and peaks determined. shows <strong>the</strong> complexity <strong>of</strong> <strong>the</strong> mixture. The <strong>chemical</strong>The total i<strong>on</strong> chromatogram <strong>of</strong> <strong>the</strong> <strong>essential</strong> <strong>oil</strong> is displayed effects <strong>on</strong> histamine in Fig.1. The release amounts from RBL-2H3 <strong>of</strong> <strong>the</strong> cells. JA comparis<strong>on</strong> with literature data showed that <strong>the</strong> Ethnopharmacol, 2001, 75(2-3): 249-56.c<strong>on</strong>stituents <strong>of</strong> <strong>the</strong> <strong>essential</strong> <strong>oil</strong> are listed in Table 1. The <strong>essential</strong> <strong>oil</strong> c<strong>on</strong>sisted mainly <strong>of</strong>major comp<strong>on</strong>ents c<strong>on</strong>stituents from in <strong>the</strong> <strong>essential</strong> volatile <strong>oil</strong> <strong>oil</strong> were determinated similar by [5] <strong>the</strong> Cimanga peak area K, Kambu normalizati<strong>on</strong> K, T<strong>on</strong>a L, method. Apers S, This De Bruyne T,to those oxygenated reported m<strong>on</strong>oterpenes, elsewhere, although m<strong>on</strong>oterpenes <strong>the</strong>re and were oxygenated sesquiterpenes.Hermans N, TottéOfJ,<strong>the</strong>se,Pieters1,8-eucalyptolL, Vlietinck AJ. Correlati<strong>on</strong>presence <strong>of</strong> several overlapping peaks shows <strong>the</strong> complexity between <strong>chemical</strong> <strong>of</strong> <strong>the</strong> mixture. compositi<strong>on</strong> The and <strong>chemical</strong> antibacterial activitydifferences in <strong>the</strong> percentage compositi<strong>on</strong>. Some trace(72.71%), α-terpineol (2.54%), terpinen-4-ol (0.34%), and <strong>of</strong> <strong>essential</strong> linalool <strong>oil</strong>s <strong>of</strong> (0.24%) some aromatic were medicinal <strong>the</strong> main plants growingor minor c<strong>on</strong>stituents <strong>chemical</strong> <strong>of</strong> c<strong>on</strong>stituents <strong>the</strong> <strong>essential</strong> have <strong>oil</strong> not are reported listed in in Table 1. in The <strong>the</strong> <strong>essential</strong> democratic <strong>oil</strong> republic c<strong>on</strong>sisted <strong>of</strong> C<strong>on</strong>go. mainly J Ethnophamacol, <strong>of</strong><strong>the</strong> literature. oxygenated m<strong>on</strong>oterpenes, while α-pinene (9.22%), and 2002, β-pinene 79(2): 213-20. (0.4%) were <strong>the</strong> mainoxygenated m<strong>on</strong>oterpenes, m<strong>on</strong>oterpenes and oxygenated [6] Osawa sesquiterpenes. K, Yasuda Of H. Macrocarpals <strong>the</strong>se, 1,8-eucalyptol H, I and J from <strong>the</strong>m<strong>on</strong>oterpenes and α-eudesmol (0.39%), (-)-globulol (2.77%), <strong>leaves</strong> and <strong>of</strong> Eucalyptus epiglobulol(0.44%) globulus. J Nat were Prod, <strong>the</strong> 1996, 59(9):References (72.71%), α-terpineol (2.54%), terpinen-4-ol (0.34%), 823-7. and linalool (0.24%) were <strong>the</strong> main[1] Liu main YM, sesquiterpene. Li SF, Wu YT. Several Advances significant in <strong>the</strong> study compounds <strong>of</strong> [7] were Dessi α-terpineol MA, Deiana acetate M, Rosa (3.1%), A, Piredda geranyl M, CottigliaEucalyptus oxygenated globulus m<strong>on</strong>oterpenes, Labill. J Chin while Med Materials, α-pinene 2003, (9.22%), and F, B<strong>on</strong>signore β-pinene L, (0.4%) Deidda were D, Pompei <strong>the</strong> R, main Cor<strong>on</strong>giu FP.26(6): acetate 461-3. (0.71%), L-pinocarveol(0.36%), β-sabinene (0.25%), Antioxidant and terpinolene activity <strong>of</strong> (0.19%). extracts A from porti<strong>on</strong> plants growing in[2] Swanst<strong>on</strong>-Flatt m<strong>on</strong>oterpenes SK, Day and C, α-eudesmol Bailey CJ, Flatt (0.39%), PR. Traditi<strong>on</strong>al (-)-globulol (2.77%), Sardinia. and Phyto<strong>the</strong>r epiglobulol(0.44%) Res, 2001, 15(6): were 511-8. <strong>the</strong>plant (0.26%) treatments <strong>of</strong> <strong>the</strong> total for diabetes. c<strong>on</strong>stituents Studies remains normal unidentified. and [8] Yun BS, Lee IK, Kim JP, Chung SH, Shim GS, Yoo ID.streptozotocin main sesquiterpene. diabetic mice. Several Diabetologia, significant 1990, compounds 33(8): were Lipid α-terpineol peroxidati<strong>on</strong> acetate inhibitory (3.1%), activity <strong>of</strong> geranyl some c<strong>on</strong>stituents462-4. The yield <strong>of</strong> <strong>essential</strong> <strong>oil</strong> and <strong>the</strong> c<strong>on</strong>tent <strong>of</strong> 1,8-eucalyptol isolated are from within <strong>the</strong> stem <strong>the</strong> bark values <strong>of</strong> Eucalyptus reported in globulus. Archacetate (0.71%), L-pinocarveol(0.36%), β-sabinene (0.25%), and terpinolene (0.19%). A porti<strong>on</strong><strong>the</strong> literature [12] and <strong>the</strong> percentage c<strong>on</strong>tents <strong>of</strong> <strong>the</strong> main c<strong>on</strong>stituents are similar to those given in(0.26%) <strong>of</strong> <strong>the</strong> total c<strong>on</strong>stituents remains unidentified.The yield <strong>of</strong> <strong>essential</strong> <strong>oil</strong> and <strong>the</strong> c<strong>on</strong>tent <strong>of</strong> 139 1,8-eucalyptol are within <strong>the</strong> values reported in

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