Siwan Choi, M.D. Chungnam National University
Siwan Choi, M.D. Chungnam National University
Siwan Choi, M.D. Chungnam National University
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Mechanisms of metabolic regulation ofvessel toneEndothelial CellVascular smooth muscle cellCardiomyocytePO 2 ↓(lumen)Ca2+↑(releasefrom ER)HSPp20 ↑cAMPVessel tone ↓Contractile force ↓K ATpH+PO 2 ↓PG ↑ACATP[Ca2+]↓HyperpolarizationA 2ACO2AdenosineCa vg