Coasting and OHSS Coast ga dO SS

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Change inE2 levels l (HCG -1to day of HCG)Cycles(n)Normal fertilizationrateNo Drop in E2 252 2123 /3236 (65.6%)E2 Drop 1-15% 15% 42 319 / 492 (64.8%)E2 Drop 16-30%59 491 / 727 (67.5%)E2 Drop 31-45%56 471 / 690 (68.3%)E2 Drop 46-60% 60% 17 133 / 183 (72.7%)P value 0.19
Change in E2 levelsCycles(%) (n)Ongoingpregnancy/Live birthrateNo Drop in E2 252 78 / 252 (31%)E2 Drop 1-15% 15% 42 14 / 42 (33%)E2 Drop 16-30%59 22 / 59 (37%)E2 Drop 31-45%56 19 / 56 (33%)E2 Drop 46-60%60% 17 5 / 17 (29%)P value 0.91
Page 1 and 2: Coasting and OHSSMrs Uma GordonBris
Page 4 and 5: Prevention of OHSS• Lower dose of
Page 6 and 7: Prevention of OHSS• Coasting - mo
Page 8 and 9: Coasting - Advantages• Cycle not
Page 10: CoastingNo clear cut criteria-When
Page 13 and 14: Coasting - start time?At BCRM, E2 d
Page 15 and 16: Coasting duration - Pregnancy rates
Page 17 and 18: Coasting challenges --what drop in
Page 19 and 20: Bristol Centre ForReproductive Medi
Page 21 and 22: Methodology• GnRH-a long protocol
Page 23 and 24: MethodologyCoasting stopped (ie., h
Page 25 and 26: Serum E2 Assay• Competitive immun
Page 27 and 28: Coastingduration(Days)Cycles(n)No.
Page 29 and 30: Coastingduration(Days)Cycles (n)Ong
Page 31: Change inE2 levels l (HCG -1to day
Page 35 and 36: Results 3• 6.1% OHSS in coasted c
Page 37 and 38: Conclusions - 2• Coasting results
Page 39 and 40: OHSS - morbidity and mortality• C
Page 41 and 42: Coasting AuditBCRM - Change of prac
Page 43 and 44: Cochrane review• Coasting vs EUFA
Page 45 and 46: Coasting versus EUFA: OHSS
Page 47 and 48: Coasting versus GnRHa: No. of oocyt
Page 49 and 50: Cochrane review• A significant be
Page 52: No room for over response or OHSSin

Coasting and OHSS Coast ga dO SS

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