WT brochure spr - Metrohm

THEINSTRUMENTS- Unique possibilities -Autolab ESPRIT allowsthe user to combineSPR measurements withelectrochemical measurementsAUTOLAB ESPRITThe surface plasmon resonancetechnique helps the scientist to analysebi-molecular interactions in real time,without labeling requirements.The study and characterization ofmolecular interactions are essential toexplore the structure-function relationshipsof biomolecules and to aid ourunderstanding of biological systems inlife sciences.Combining electrochemistry withSPR makes the Autolab ESPRIT perfectfor biosensor and DNA/RNA or proteinchip research.The double channel ESPRIT isdesigned with an open cuvette system,giving the user access to the cuvette aswell as the gold disk.The first channel is used to measurethe specific binding of the sample, thesecond channel is used to compensatefor non-specific binding, matrix andtemperature effects.The integrated high throughputautosampler provides the possibility tomeasure multiple samples automaticallywithout attendance, it also provides theoption to recover precious samples orunknown interacted molecules.ESPRIT comes with powerful dataacquisition software, which includesautomation tools for instrument control.All recorded data is evaluated in aseparate kinetic evaluation package, theraw data can also be exported into anythird party file formats. An additionalsoftware component to comply with GLPguidelines is available.Application areas● Chemical sensors● Affinity sensors● ImmunosensorsFundamental prerequisites● Efficient and stable immobilization● Complete retention of the biologicalproperties of the sample under study● Accessibility of biomoleculesKey features● Automated high throughput● Open cuvette system with referencechannel● Large dynamic refractive index rangePAGE 3