SUNDAY December 7, 2008Afternoon Session I – 2:15 p.m. - 3:45 p.m.7. fMRI and Memory: Advances and PromisesCC – Room 612Moderators: Mary Lou Smith, Ph.D. and William D. Gaillard, M.D.Speakers: Mary Pat McAndrews, Ph.D., Silvia Bonelli, M.D.,Madison Berl, Ph.D.8. The Dentate “Gate”: What Is It, What Regulates It, and Is ItCompromised in <strong>Epilepsy</strong>?CC – Room 607Moderator: Douglas A. Coulter, Ph.D.Speakers: Douglas A. Coulter, Ph.D., Ivan Soltesz, Ph.D.,Istvan Mody, Ph.D., Robert Brenner, Ph.D.9. Do Anticonvulsants Injure the Immature Brain?CC – Room 603Moderator: Jong M. Rho, M.D.Speakers: Chrysanthy Ikonomidou, Richard H. Finnell, Ph.D.,Kimford J. Meador, M.D.Break: 3:45 p.m. - 4:15 p.m.Afternoon Session II – 4:15 p.m. - 5:45 p.m.10. The Comorbidities of <strong>Epilepsy</strong>: The Unification of Multiple DiseaseStates Through Basic MechanismsCC – Room 603Moderator: Molly Huntsman, Ph.D.Speakers: Robert K. S. Wong, Ph.D., Kevin C. Ess, M.D., Ph.D.,L. Mucke, Alison Barth, Ph.D.11. Interactions Within the Neurovascular Unit and EpileptogenesisCC – Room 607Moderator: Alon Friedman, M.D., Ph.D.Speakers: Daniela Kaufer, Ph.D., Christian Steinhaeuser, Ph.D.,Brian MacVicar, M.D., Ph.D., Mirielle Lerner-Natoli12. Surrogate Markers in Animal Models of Acquired <strong>Epilepsy</strong>: TheGood, The Bad and The UglyCC – Room 612Moderator: F. Edward Dudek, Ph.D.Speakers: F. Edward Dudek, Ph.D., Tallie Z. Baram, M.D., Ph.D.,Edward H. Bertram III, M.D., Frances E. Jensen, M.D.4:00 p.m. – 6:00 p.m.Professionals in <strong>Epilepsy</strong> Care Symposium:The Evaluation and Treatment of thePatient with Developmental Delay and<strong>Epilepsy</strong>: A Multidisciplinary ApproachCC – Ballroom 6ELearner Outcomesu Define current best practice regarding patient management of personswho have both epilepsy and IDu Develop a framework to evaluate medical and psychosocial needsof the patientsu Develop strategies to apply the framework for this patient population.Target AudienceNeurologists, pediatric neurologists, psychiatrists, pediatric psychiatrists,internists and family physicians, pediatricians, neuropsychologists,psychologists, nurses, social workers, medical students and pharmacists<strong>Program</strong>Co-Chairs: Kathryn A. O’Hara, RN and Andres M. Kanner, M.D.FacultyJames W. Wheless, M.D., Michael Schrift, D.O., Sigita Plioplys, M.D.,Patricia Gibson, M.S.S.W., Vickie Brewer, Ph.D., Janice M. Buelow, RN, Ph.D.,Alan B. Ettinger, M.D.Introduction and <strong>Program</strong> OverviewAndres M. Kanner, M.D.Review of Behavioral and Family Issues by IQJanice M. Buelow, RN, Ph.D.Question and Answer SessionAdult Case DiscussionFaculty PanelQuestion and Answer SessionPediatric Case DiscussionFaculty PanelQuestion and Answer SessionConclusionCredit DesignationThe <strong>American</strong> <strong>Epilepsy</strong> <strong>Society</strong> designates this education activity for amaximum of 2.0 AMA PRA Category 1 Credits TM . Physicians should only claimcredit commensurate with the extent of their participation in the activity.Submitted to the Association of Rehabilitation Nurses (ARN) for 2.0 contacthours. ARN is accredited as an approver of continuing nursing education bythe <strong>American</strong> Nursing Credentialing Center’s Commission on Accreditation.Pharmacy CreditACPE # 073-999-08-151-L01-P; 0.2 CEUsAcknowledgmentThis program is supported by an educational grant from ValeantPharmaceuticals International.OverviewThis program addresses the scope and depth of neurological, medical,psychiatric and psycho social problems encountered in treating persons withepilepsy and developmental delay. We will review the epidemiologic aspectsof developmental delay and epilepsy, the extent of the comorbidity betweendevelopmental delay and epilepsy, the impact of epilepsy on cognition andcurrent behavioral research. These points will be illustrated in tworepresentative case presentations discussed by a multidisciplinary panel ofexperts.42AES 62 ND ANNUAL MEETING 2nd Biennial North <strong>American</strong> Regional <strong>Epilepsy</strong> Congresswww.AESNET.org
SUNDAY December 7, 20086:00 p.m. – 7:30 p.m.Reception in Support of the Lennox /Lombroso Research Trust FundCC – Hall 4BShare the dream to cure epilepsy! Come mingle with your colleagues andshow your support at the Annual Reception. A voluntary, tax deductiblecontribution of $50, or whatever you can contribute, will benefit theLennox/Lombroso Research Trust Fund. To assist in planning, advancedregistration is required.AcknowledgmentThis reception is supported by grants from UCB, Inc., Pfizer Inc., and Questor.Additional support from attendees.6:00 p.m. – 7:30 p.m.Investigators’ Workshop Poster SessionCC – Hall 4BThis evening poster session features basic science posters in the poster areain the Exhibit Hall. See poster numbers IW.56 - IW.757:30 p.m. – 9:00 p.m.Special Interest Group MeetingsBasic Neuroscience – Advances In Technologies That CanBenefit <strong>Epilepsy</strong> ResearchCC – Room 603Coordinators: Celine Dube, Ph.D., Brenda E. Porter, M.D., Ph.D.Karen S. Wilcox, Ph.D.Speakers: Jennifer A. Kearney, Ph.D., Sanjay Kumar, Ph.D.,Douglas A. Coulter, Ph.D.A group of basic neurobiologists and translational epilepsy researchers willdiscuss an emerging topic in epilepsy research with lots of time fordiscussion. The topics this year include laser scanning for synapticconnectivity assays, DNA sequencing technology, medical re-sequencing, SNPdetection technologies and whole genome associations, and our final topicwill be the use of voltage gated dyes.Clinical Nursing – Emergencies in the <strong>Epilepsy</strong>Monitoring UnitCC – Room 617Coordinators: Sarah Kiel, M.S.N., CPNP, Irene Dustin, M.S.N., CRNPSpeakers: Linda Allen, RN, B.S.N.; Pat Dean, M.S.N., ARPN,Delia Nickolaus, M.S.N., CPNPWe plan to present case studies, review available practiceparameters/guidelines, and discuss problems, outcomes and areas forimprovement in managing emergencies in the <strong>Epilepsy</strong> Monitoring Unit.How to Obtain NIH Funding – NIH Resources forClinical TrialsCC – Room 618Coordinator: Randall Stewart, Ph.D.Successful investigators will provide tips and strategies for writingcompetitive clinical reserach applications. Information about NINDS fundingopportunities can be found at http://www.ninds.nih.gov.Neuroimaging – Novel Approaches to Imaging <strong>Epilepsy</strong>CC – Room 607Coordinator: Hoby P. Hetherington, Ph.D.Speakers: Olli Gröhn and Theodore SchwartzTopics to be covered include: 1. Optical Imaging in <strong>Epilepsy</strong>; 2. MolecularImaging of <strong>Epilepsy</strong> Using Novel Tracers; 3. Tracking Neuronal Activity UsingMRI.Pediatric <strong>Epilepsy</strong> – Case PresentationsCC – Room 612Coordinator: Elaine Wyllie, M.D.Please join us so that we can learn from each other and from our experiencewith pediatric patients! Our seasoned faculty will present exciting cases fromtheir own clinical practice, and also comment on selected cases presented byyou or other SIG members. Topics will include diagnosis and treatment ofepileptic seizures; seizure semiology and EEG features of epilepsy in children;innovative approaches to treatment; recognition and management ofcongenital and acquired etiologies of pediatric epilepsy; and age-relatedfactors in epilepsy surgery.SUDEP – What Is Needed to Solve the Enigma?CC – Room 615Coordinators: Elson L. So, M.D., Tess L. Sierzant, RN, M.S.Speakers: Margaret Jacobs, Jeffrey L. Noebels, M.D., Ph.D.,Georgia D. Montouris, M.D.Since last year’s SUDEP SIG meeting in Philadelphia, the AES & EF Joint TaskForce on SUDEP has completed its report and recommendations. An overviewof the Task Force Report will be presented at this year’s SIG. The goal is tosolicit comments on issues involving SUDEP research and education. TheSUDEP rate in medically-refractory epilepsy patients is about one in 100person-years — a rate that requires an unusually large study population foryielding sufficient data. Therefore, traditional methods of clinical investigationsmay not work in determining the cause of SUDEP. The lack of detectable andreliable markers also makes it difficult to identify and follow patients at highrisk. The prevailing low rates of complete autopsies present specialchallenges to SUDEP studies. Basic science research must be encouraged tobetter guide the direction of clinical investigations into the cause andprevention of SUDEP. The limitations in existing SUDEP knowledge underscorethe importance of educating patients, families and healthcare providers. SIGparticipants will also discuss the Task Force recommendations of “who, whenand how” to counsel about SUDEP.Surgery – Difficult Cases and PathologyCC – Ballroom 6ECoordinator: Michael M. Haglund, M.D., Ph.D.Speakers: TBAWe plan again to have exciting presentation and discussion of difficult casesthat involve surgery. We hope to add a neuropathology component this yearto incorporate this critical feature of the surgical resections being discussed.Translational Research – Intellectual Property: Legal,Tech Transfer, Finance, Competitive and CollaborativePerspectivesCC – Room 620Coordinators: Thomas P. Sutula, M.D., Ph.D., Warren LammertSpeakers: TBASpeakers will provide an overview of intellectual property concepts and willdiscuss how to work with IP firms, university tech transfer offices andsophisticated database tools to understand and define intellectual propertyrelevant to a research area or project.www.AESNET.orgAES 62 ND ANNUAL MEETING 2nd Biennial North <strong>American</strong> Regional <strong>Epilepsy</strong> Congress43
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- Page 73 and 74: ABSTRACT AUTHOR INDEXAAarnoutse, E.
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