AES SPECIAL RECOGNITION2008 Early Career Physician-Scientist AwardsFriday, December 5 – 3:30 p.m. - 3:45 p.m., Ballroom 6E(immediately preceding the Hoyer Lecture)Supported by the Milken Family FoundationThis program seeks to encourage the development of new therapies for epilepsy by providing research training for physicians early in their academic career. These awards are primarilyfor investigators whose research interests will potentially affect epilepsy patients in the near term. Applications are reviewed on the basis of: the applicant’s commitment to a researchcareer, the training record of the mentor and epilepsy center and the quality and relevance of the research project for developing cures for epilepsy.David K. Chen, M.D.Michael E. DeBakey VA Medical Center, Baylor College of MedicineMentor: Harvey S. Levin, Ph.D.Diffusion Tensor and Magnetization Transfer Imaging of Mesial Temporal Pathologies inPosttraumatic <strong>Epilepsy</strong>Autumn Klein, M.D., Ph.D.Brigham and Women’s HospitalMentor: Edward B. Bromfield, M.D.Obstetrical and Neurological Complications in Women with <strong>Epilepsy</strong>: A Prospective StudyTobias Loddenkemper, M.D.Children’s Hospital of BostonMentor: Frances E. Jensen, M.D.Glutamate and GABA Receptor Subunit Changes During Status Epilepticus in ChildrenJoseph Parvizi, M.D., Ph.D.Stanford UniversityMentor: Robert S. Fisher, M.D., Ph.D.The Neuroanatomy of Seizure Propagation<strong>Epilepsy</strong> Research Recognition AwardsMonday, December 8 – 9:00 a.m. - 9:15 a.m., Ballroom 6E(immediately preceding the Presidential Symposium)The <strong>American</strong> <strong>Epilepsy</strong> <strong>Society</strong> <strong>Epilepsy</strong> Research Recognition Awards are given annually to active scientists and clinicians working in all aspects of epilepsy research. They are designedto recognize professional excellence reflected in a distinguished history of research or important promise for the improved understanding, diagnosis and treatment of epilepsy. Theawards of $10,000 each are part of the AES grant and fellowship programs.Award for Basic ScienceFrances E. Jensen, M.D.Award for Clinical ScienceAnne T. Berg, Ph.D.Frances E. Jensen, M.D., is a professor of neurology at Children’s Hospital Boston andHarvard Medical School, where she is also director of epilepsy research. She received anM.D. from Cornell University Medical College in 1983. She performed her internship inInternal Medicine at Brigham and Women’s Hospital in Boston and her assistant residencyin Neurology at The Harvard Longwood Neurology Training <strong>Program</strong>, in Boston, where shewas also Chief Resident.Dr. Jensen, a recipient of the NIH Director’s Pioneer Award, has identified uniquemechanisms involved in seizure activity and injury in the developing brain, leading to newcandidate therapies in development for clinical trials in newborns. Dr. Jensen’s researchfocuses on mechanisms of epileptogenesis and cortical injury in the developing brain, withspecific emphasis on neonates. Her work has yielded new candidate therapies fortreatments presently under development for clinical trials. In addition, her work exploreshow seizures alter neuronal networks to result in learning deficits, neuropsychiatricsymptoms and autism.Dr. Jensen also is a practicing physician in neurology at both Children’s Hospital andBrigham and Women’s Hospital. She is Chair of the <strong>Program</strong> Committee at the <strong>Society</strong> forNeuroscience, past Chair of the AES Council on Education and of the Advocacy Committee.She is currently serving as a member of the Board of Directors. In addition she serves onseveral editorial boards as an ad hoc reviewer and is an Editorial Board member for Annalsof Neurology.Anne T. Berg, Ph.D. received her doctorate in epidemiology from Yale University in 1986.Since then, her research has focused on the clinical epidemiology of seizure disorders withan emphasis on delineating short- and long-term seizure outcomes as well as thebehavioral, cognitive and social co-morbidities frequently associated with epilepsy. Herresearch has encompassed the prognosis following febrile seizures, their relation to newonset epilepsy, and their prognostic significance with respect to intractable epilepsy and theoutcomes of epilepsy surgery. She has also worked extensively on the prognosis following afirst unprovoked seizure, the role of syndromes in studying seizure and other outcomes inepilepsy, intractable epilepsy, and epilepsy surgery. She is studying early imaging markersand clinical correlates of mesial temporal lobe epilepsy as well as studying long-termsocial, educational, and behavioral difficulties in young adults who had epilepsy aschildren. Dr. Berg has had 20 years of continuous funding from the National Institute ofNeurological Diseases and Stroke, including a Javits Neuroscience Investigator Award in2007 to pursue these areas of research. She has published extensively in the field ofepilepsy.Dr. Berg is finishing a term as an associate editor of Epilepsia and is the current Chair ofthe ILAE Commission on Classification and Terminology. She is also a co-chair for theNINDS benchmark on co-morbidities in epilepsy.8AES 62 ND ANNUAL MEETING 2nd Biennial North <strong>American</strong> Regional <strong>Epilepsy</strong> Congresswww.AESNET.org
AES SPECIAL RECOGNITION2008 William G. Lennox AwardMonday, December 8 – Ballroom 6C9:00 a.m.-9:15 a.m.(immediately preceding the PresidentialSymposium)2008 William G. Lennox LecturerMonday, December 8 – Ballroom 6C2:15 p.m.-3:00 p.m.Harvey Kupferberg, Ph.D., Pharm.D.Dr. Harvey Kupferberg began his epilepsy research while teaching at the University ofMinnesota’s Department of Pharmacology. His first research project looked at a proposeddrug-drug interaction between methylphenidate and clinically effective anticonvulsantdrugs. The project required the development of analytical procedures for the simultaneousdetermination of the AEDs. In 1971, his analytical skills came to the attention of Dr. J.Kiffin Penry at the NINDS who recruited him to join the <strong>Epilepsy</strong> Branch. A laboratory wasestablished to develop analytical procedures for the Branch’s clinical trials in epilepsy,which Dr. Kupferberg administered.In 1980, Dr. Kupferberg was promoted to Chief, Preclinical Pharmacology Section of the<strong>Epilepsy</strong> Branch at NINDS/NIH. It was in this position that he helped establish theAntiepileptic Drug Development <strong>Program</strong> (ADD) to screen and evaluate new chemicalentities for their potential in treating epilepsy. He was the government’s liaison betweenthe pharmaceutical industry and the Anticonvulsant Screening Project at the University ofUtah. Under his supervision and direction, the ADD program evaluated the anticonvulsantpotential of over 20,000 new chemical entities. Several of those compounds are nowbeing used to treat epileptic seizures. His laboratory helped establish the metabolicpathways of some of the ADD <strong>Program</strong> drugs. In the late 1990s his laboratory initiatedcollaborative efforts with the FDA and the University of Virginia to understand themechanisms by which felbamate caused both hepatic damage and aplastic anemia.Dr. Kupferberg has received a number of awards during his tenure at the NINDS. He andhis colleagues received the ILAE 1982 annual prize for the best published controlledclinical trial of an AED. In 1985, he was named ILAE <strong>Epilepsy</strong> Ambassador and in 1988received the ILAE Award of Merit for outstanding contributions in pharmacologicdevelopment of AEDs. Dr. Kupferberg received the first AES Service Award in 1994.He retired from the NINDS in 2000 and continues to consult for the pharmaceuticalindustry.2008 AES Service AwardSaturday, December 6 – Ballroom 6C9:00 a.m.-9:15 a.m.(immediately preceding theMerritt-Putnam Symposium)Elinor Ben-Menachem, M.D., Ph.D.Elinor Ben-Menachem, M.D., Ph.D., is Professor of Neurology and <strong>Epilepsy</strong> at the Institutefor Clinical Neurosciences and Physiology, Göteborg University, Göteborg, Sweden.Dr. Ben-Menachem was born in Los Angeles and graduated from the University ofCalifornia, Los Angeles. She went to Uppsala, Sweden on the California International<strong>Program</strong> and studied medicine. She received her M.D. and Ph.D. degrees in neurology atGöteborg University in Sweden. Dr. Ben-Menachem did an <strong>Epilepsy</strong> Fellowship at the VA-UCLA in Los Angeles. She has been the chair of the ILAE Antiepileptic Drug GuidelineSubcommittee and is currently chair of the AES Annual Course Committee while serving asChief Editor of Acta Neurologica Scandinavica. Other AES committees she has served onare: Corporate Advisory, Scientific <strong>Program</strong>, Clinical Therapeutics, Clinical Investigators’,Council on Education, International Relations and she has been an <strong>Epilepsy</strong> CurrentsEditor since 2005. Dr. Ben-Menachem is an active member of the Swedish MedicalAssociation, Swedish Neurology Association, Swedish <strong>Epilepsy</strong> <strong>Society</strong>, Danish <strong>Epilepsy</strong><strong>Society</strong>, <strong>American</strong> <strong>Epilepsy</strong> <strong>Society</strong>, <strong>American</strong> Academy of Neurology and <strong>American</strong>Neurological Association as well as a fellow of the Royal College of Physicians, Edinburgh.Other academic activities include Evaluator for EU grants in epilepsy and Evaluator forGrants for general medical research for the Western Region of Sweden.Robert S. Fisher, M.D., Ph.D.Dr. Fisher is Maslah Saul, M.D. Professor of Neurology and Director of the Stanford<strong>Epilepsy</strong> Center. He has won research awards from the Klingenstein Foundation, the<strong>Epilepsy</strong> Foundation of America and the National Institutes of Health. His peers namedhim to be listed 1996-2007 in Best Doctors in America. He was given theAmbassador Award from the International League Against <strong>Epilepsy</strong>, the 2005 AES ServiceAward and the 2006 Annual Research Award (clinical). Dr. Fisher is Past-President of the<strong>American</strong> <strong>Epilepsy</strong> <strong>Society</strong>, and has served on the Board of the International LeagueAgainst <strong>Epilepsy</strong> and as Editor-in-Chief of the Journal, Epilepsia. He currently is Editor-in-Chief of the Web site epilepsy.com.2008 J. Kiffin Penry Excellencein <strong>Epilepsy</strong> Care AwardSaturday, December 6 – Ballroom 6C5:00 p.m.-5:15 p.m.(immediately preceding the AETSymposium)Eileen P. G. Vining, M.D.Dr. Patti Vining is the Lederer Professor of Pediatric <strong>Epilepsy</strong>, Professor of Neurology andPediatrics at the Johns Hopkins University School of Medicine. She is the Director of theJohn M. Freeman Pediatric <strong>Epilepsy</strong> Center at Johns Hopkins and Director of the <strong>Epilepsy</strong>Monitoring Unit. Dr. Vining received her M.D. from Johns Hopkins University School ofMedicine, and trained in Pediatrics at the Children’s Hospital of Pittsburgh, followed by afellowship in Developmental Pediatrics at the Kennedy Institute/Johns Hopkins. She is afellow of the <strong>American</strong> Academy of Pediatrics.Dr. Vining has had a long commitment to the assessment and care of the “whole child,”recognizing that epilepsy occurs in the setting of all the individual elements that need tobe optimized for the child and family to do well. This is at the foundation of the book thatshe co-authored with John Freeman and Diana Pillas, Seizures and <strong>Epilepsy</strong> inChildhood: A Guide. Early in her professional life, she had the remarkableopportunity of working with Dr. Penry, Dr. Dreifuss and Pat Gibson to develop andimplement a program to understand issues about Quality of Life for people with epilepsy.In her career at Hopkins she helped develop a program focused on the comprehensivecare of children with epilepsy, and has championed the thoughtful use of surgery and theketogenic diet for children with intractable epilepsy. She has focused her research effortsin three areas: surgery for epilepsy in children (especially hemispherectomy), theketogenic diet, and the impact of epilepsy and its treatment on the child.She has been active in the <strong>American</strong> Academy of Pediatrics, serving on their NationalMeeting and Scientific Exhibition Planning Group and the Executive Committee for ChildNeurology. She has served on numerous AES committees including: the Scientific <strong>Program</strong>Committee, Continuing Medical Education Committee, and the Year Round EducationCommittee (Pediatrics). She has also served the <strong>Epilepsy</strong> Foundation, locally andnationally, in a variety of capacities.www.AESNET.org AES 62 ND ANNUAL MEETING 2nd Biennial North <strong>American</strong> Regional <strong>Epilepsy</strong> Congress 9
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ABSTRACT AUTHOR INDEXAAarnoutse, E.
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ABSTRACT AUTHOR INDEXCarrete, Jr.,
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