12.07.2015 Views

Birmingham Environment for Academic Research - University of ...

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Micro- and Macromixing Studies in Two- and Three-Phase (Gas-Solid-Liquid) StirredMixing on a molecular scale (micromixing) has been studied extensively because <strong>of</strong> its potential importancein industrial chemical reactors, which are commonly used in pharmaceutical, chemical, biochemicaland other industries. Better understanding <strong>of</strong> these phenomena would be beneficial <strong>for</strong> optimisingproduct distributions, <strong>for</strong> instance to achieve required yield and quality <strong>of</strong> the product in polymerisationor precipitation. In this study, mixing in baffled and unbaffled stirred tanks is <strong>of</strong> particular interestand detailed in<strong>for</strong>mation about the fluid flow in these two cases might help interpreting or even explainingresults from experimental work.In addition to well established experimental techniques, computer simulations, i.e. Computational FluidDynamics (CFD), can be helpful <strong>for</strong> studying fluid flow phenomena using numerical methods. Models <strong>of</strong>baffled and unbaffled stirred vessels are being simulated using the commercial s<strong>of</strong>tware package CFX.The region around the feed pipe is <strong>of</strong> particular importance <strong>for</strong> micromixing and is resolved with finestructured meshing.The results from CFD simulations are being validated with experimental findings, <strong>for</strong> instance the impeller power number, and shouldlead to a better understanding <strong>of</strong> the studied cases. In the long run, established models might be solely used to look at various potentialscenarios applied to stirred reactors <strong>for</strong> achieving better results without the need <strong>for</strong> expensive and cumbersome experiments.Julia H<strong>of</strong>ingerDepartment <strong>of</strong> Chemical EngineeringPage 18

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