Oral contraceptives and venous thrombosis. An ... - Ãjvind Lidegaard

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VTE <strong>and</strong> drospirenoneVTE Risk Rate rationo /10,000 DRSP/2nd genEURAS 07 118 9.1 1.0 (0.6-1.8) 4th/2ndSeeger 07 57 13.0 * 0.9 (0.5-1.6) 4th/???Vlieg 09 1,524 na 1.7 (0.7-3.9) 4th/2nd<strong>Lidegaard</strong> 09 4.213 7.8 1.6 (1.3-2.1) 4th/2nd
Research story• 1960s: OC were introduced with success• 2001: Yasmin came on the market• 2007: Yasmin most selling OC• 2007, June: Case report in Danish media• 2007: First publication on VTE (Dinger)• 2009 June: BMJ HC-VTE, 1995-2005• 2009: FDA requires label changes in USA• 2009: Legal recruitment for lawsuits• 2009 Dec: Bayer invites for expert meeting
Page 1 and 2: Oral contraceptionand venous thromb
Page 3 and 4: COC DK 2009: Progestogen typesCypro
Page 6: OC and VTE: Progestagen typeadjuste
Page 9: VTE and drospirenoneVTE Risk Rate r
Page 13 and 14: Preliminary AgendaDefinitions• We
Page 16 and 17: Critique In the Danish study the co
Page 18 and 19: EditorialGrimes, Obstet Gynecol Nov
Page 20 and 21: Research using vital Definitionsrec
Page 22 and 23: Research story• 2010, Jan: Shapir
Page 24 and 25: Research story• 2010, Jan: Shapir
Page 27 and 28: Oral contraception and VTEA Nationa
Page 29 and 30: InclusionMaterial• All women in D
Page 31 and 32: MaterialExclusions (
Page 33 and 34: Risk of VTE according to yearAdjust
Page 35 and 36: Relative risk versus non-useRate ra
Page 37 and 38: VTE and drospirenoneVTE Risk Rate r
Page 39 and 40: VTE and drospirenoneVTE Risk Rate r
Page 41 and 42: VTE and drospirenoneVTE IR Rate rat
Page 43 and 44: HC and VTE according to oestrogendo
Page 45 and 46: VTE and drospirenoneVTE IR Rate rat
Page 47 and 48: Blomenkamp88-92WHO1989-93Jick1991-9
Page 49 and 50: OCs and SHBG changes400% increase i
Page 51 and 52: COC and VTE: Conclusion• COC incr
Page 53 and 54: CT, AMI and VTE in DK 2001-2009Preg
Page 55 and 56: COC and VTE: Perspectives• Parent
Page 57 and 58: COC and VTE: Perspectives• Parent
Page 59: COC and VTE: PerspectivesThankswww.

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Oral contraceptives and venous thrombosis. An ... - Ãjvind Lidegaard