CLINICAL PRESENTATION AND MANAGEMENT OF PERTUSSIS

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Case DefinitionLaboratory criteria for diagnosis• Isolation of Bordetella pertussis from clinicalspecimen,OR• Positive polymerase chain reaction (PCR) assay forB.pertussis.OR• Positive paired sera for B.pertussis.
Case Classification; Pertussis• Suspected: A case that meets the clinical case definition.• Confirmed:i. A clinical compatible case with B.pertussis isolation,ORii. A case that meet the clinical case definition and is confirmed by PCR, ORiii. A case that meet the clinical case definition and is confirmed serology testwith 4 fold rise of antibody in paired sera, ORiv. A case that meet the clinical case definition and is epidemiologically linkeddirectly to a confirmed case (first generation contact) by either culture orPCR.• In an outbreak settings with two or more cases epidemiologically linked, acase may be defined as a case with cough illness lasting more than 14 days.
Page 1 and 2: DR HASNI IBRAHIMFMSKK SELISING
Page 3 and 4: DTaP-IPV/Hib - KomposisiDifteriaHib
Page 5 and 6: PERTUSSIS• Respiratory infection
Page 7 and 8: CLINICAL PRESENTATION• Illness is
Page 9 and 10: • Paroxysmal• Coughing spells w
Page 11 and 12: Stages of pertussis inf and period
Page 13 and 14: Laboratory diagnosisDetection of B
Page 15 and 16: • PCR assay for B pertussisRecomm
Page 17 and 18: • Prophylaxis• Significant expo
Page 19: Disease SurveillanceCase Definition
Page 23 and 24: Purpose of reporting & investigatio
Page 26 and 27: Outbreak investigationDefinition of
Page 28 and 29: Control of Patient & Contacts• Is
Page 30 and 31: Control in Healthcare settings• C
Page 32 and 33: Preventive Measures• Educate the

CLINICAL PRESENTATION AND MANAGEMENT OF PERTUSSIS

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