2012 annual cancer report - Sutter Health Sacramento Sierra Region

SHSSR Summary of Hereditary Breastand Ovarian Cancer Syndrome Genetic Testing200180160140120100806040200SHSSRPersonal HistoryBreast CancerPersonal HistoryOvarian CancerPersonal Historyof Breast andOvarian CancerFamily History ofBreast or OvarianCancer or knownHBOC MutationTwo-hundred eighty patients were referred for evaluation of HBOC Syndrome. Onehundred eighty-three of those patients had a personal history of breast cancer. Twentyonepatients had a personal history of ovarian cancer. Three patients presented with apersonal history of both breast and ovarian cancers. Seventy-one patients had a familyhistory of breast and/or ovarian cancer, or a known HBOC Syndrome mutation.SHSSR Summary of Lynch Syndrome Genetic Testing181614121086420SHSSRPersonal HistoryColon CancerPersonal HistoryUterine CancerPersonal Historyof Colon andUterine CancerPersonal HistoryLynch SyndromeRelated CancerFamily HistoryColon or UterineCancer or LynchMutationThe second most common genetic test performed in our Cancer Centers was forLynch Syndrome. Eighteen patients presented with a primary diagnosis of coloncancer. One patient had a personal history of uterine cancer, and one patient hada personal history of both colon and uterine cancer. Two patients had a personalhistory of other Lynch Syndrome-related cancers, including ovarian and stomachcancer. Fourteen of the patients tested had a family history of colon and/or uterinecancer, or a known Lynch Syndrome mutation.2012 Annual Cancer Program Report 21