MRCS PART A ESSENTIAL REVISION NOTES BOOK 1 - PasTest
MRCS PART A ESSENTIAL REVISION NOTES BOOK 1 - PasTest
MRCS PART A ESSENTIAL REVISION NOTES BOOK 1 - PasTest
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SECTION 2Preoperative management ofcoexisting diseaseCHAPTER 12.1 PreoperativemedicationsReview pre-existingmedicationIn a nutshell …If a patient is having surgery: Review pre-existing medication: Document preoperativemedications Decide which drugs need to bestopped preoperatively Decide on alternative formulations Prescribe preoperative medication: Prescribe prophylactic medication Prescribe medication related to thesurgery Prescribe premed if needed Be aware of problems with specificdrugs: Steroids and immunosuppressants Anticoagulants and fibrinolyticsPerioperative management ofpre-existing medicationDocument preoperative medicationsDecide whether any drugs need to bestopped before surgery Stop oral contraceptive (OCP) ortamoxifen 4 weeks before major orlimb surgery – risk of thrombosis Stop monoamine oxidase inhibitor(MAOI) antidepressants – they interactwith anaesthetic drugs, with cardiacrisk Stop antiplatelet drugs 7–14 dayspreoperatively – risk of haemorrhageDecide on alternative formulations forthe perioperative period For example, IV rather than oral,heparin rather than warfarin17