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Metabolische Azidose : PlasmaanionenlŸcke - Universität Konstanz

Metabolische Azidose : PlasmaanionenlŸcke - Universität Konstanz

Metabolische Azidose : PlasmaanionenlŸcke - Universität Konstanz

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Release properties of (PLGA) microspheres:<br />

� Spray-dried PLGA 50:50 polymer<br />

� 3-5 µm in diameter<br />

� Complete degradation within 2-3 weeks<br />

� Initial burst and delayed releases of the containing<br />

antigen<br />

Thomasin et al.<br />

(1996) J. Contr.<br />

Release 41: 131-145<br />

release<br />

degradation<br />

tetanus toxoid (150 kD)<br />

University of Constance

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