Herzinsuffizienz, VAD, Herztransplantation - FINeST

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2. Januar 2012 When the heart does not start (up)… … after Transplantation
CAUSE OF DEATH Cardiac Allograft Vasculopathy 2. Januar 2012 0-30 Days (N = 3,771) Does it really happen? 31 Days – 1 Year (N = 3,675) >1 Year – 3 Years (N = 2,848) >3 Years – 5 Years (N = 2,448) >5 Years – 10 Years (N = 5,592 ) >10 Years – 15 Years (N =3,070) >15 Years (N =1,075) 63 (1.7%) 173 (4.7%) 394 (13.8%) 386 (15.8%) 806 (14.4%) 455 (14.8%) 134 (12.5%) Acute Rejection 242 (6.4%) 442 (12.0%) 292 (10.3%) 110 (4.5%) 100 (1.8%) 28 (0.9%) 8 (0.7%) Lymphoma 2 (0.1%) 69 (1.9%) 93 (3.3%) 106 (4.3%) 254 (4.5%) 119 (3.9%) 43 (4.0%) 1992-2009: 58600 Htx „Graft Failure“� n=5000 (8,6 %) 0-30 days „Graft Failure“� n=1550 (2,7 %) Malignancy, Other 4 (0.1%) 82 (2.2%) 311 (10.9%) 448 (18.3%) 1,064 (19.0%) 599 (19.5%) 188 (17.5%) CMV 4 (0.1%) 44 (1.2%) 18 (0.6%) 5 (0.2%) 6 (0.1%) 1 (0.0%) 0 Infection, Non-CMV 484 (12.8%) 1,116 (30.4%) 365 (12.8%) 245 (10.0%) 601 (10.7%) 313 (10.2%) 131 (12.2%) Graft Failure 1,553 (41.2%) 651 (17.7%) 681 (23.9%) 495 (20.2%) 1,015 (18.2%) 499 (16.3%) 153 (14.2%) Technical 270 (7.2%) 42 (1.1%) 19 (0.7%) 19 (0.8%) 41 (0.7%) 27 (0.9%) 11 (1.0%) Other 201 (5.3%) 303 (8.2%) 272 (9.6%) 211 (8.6%) 518 (9.3%) 275 (9.0%) 104 (9.7%) Multiple Organ Failure 508 (13.5%) 419 (11.4%) 144 (5.1%) 132 (5.4%) 382 (6.8%) 236 (7.7%) 90 (8.4%) Renal Failure 24 (0.6%) 36 (1.0%) 46 (1.6%) 88 (3.6%) 332 (5.9%) 254 (8.3%) 105 (9.8%) Pulmonary 154 (4.1%) 147 (4.0%) 111 (3.9%) 120 (4.9%) 235 (4.2%) 134 (4.4%) 59 (5.5%) Cerebrovascular 262 (6.9%) 151 (4.1%) 102 (3.6%) 83 (3.4%) 238 (4.3%) 130 (4.2%) 49 (4.6%) J Heart Lung Transplant. 2010 Oct; 29 (10): 1083-1141
Page 1 and 2: 2. Januar 2012 Herzinsuffizienz, VA
Page 3 and 4: Ca. 2/3 der Fälle Meist erhaltene
Page 5 and 6: 2. Januar 2012
Page 9 and 10: 2. Januar 2012 Jessup M et al. N En
Page 11 and 12: 2. Januar 2012 Herzunterstützungss
Page 15 and 16: 40 30 20 10 0 2. Januar 2012 Periop
Page 17 and 18: 2. Januar 2012 Therapiekonzepte 1.
Page 19 and 20: 2. Januar 2012 Indikationsstellung
Page 21 and 22: 2. Januar 2012 P. B.
Page 23 and 24: ECMO: Nur kurzzeitige Überbr berbr
Page 25 and 26: 2. Januar 2012 DeBakey LVAD Steueru
Page 27 and 28: 2. Januar 2012 Novacor Novacor Plus
Page 29 and 30: 2. Januar 2012 Zukunft ist da: HVAD
Page 31 and 32: Berlin Heart Excor 2. Januar 2012
Page 33 and 34: 2. Januar 2012 AbioCor
Page 37 and 38: ORGAN 2. Januar 2012 ISHLT ISHLT RE
Page 39 and 40: 2. Januar 2012 % of Cases ReTX 2% C
Page 41 and 42: �EF < 20% � CI < 2 l/min/m2 2.
Page 51: 2. Januar 2012 P. B.
Page 57 and 58: 2. Januar 2012 Immunsuppression Sli
Page 59 and 60: % of Patients 100 80 60 40 20 0 2.
Page 63 and 64: Incidence of Cause-Specific Deaths
Page 65 and 66: Recipient age Donor age Recipient h
Page 67 and 68: % Freedom from OB Freedom from Bron
Page 69 and 70: 2. Januar 2012 Idiopathische Lungen
Page 71 and 72: 2. Januar 2012 DIAGNOSIS IN ADULT H
Page 73 and 74: 2. Januar 2012 Herz-Lungen-Transpla
Page 75 and 76: 100% 90% 80% 70% 60% 50% 40% 30% 20
Page 77 and 78: Number of Transplants NUMBER OF HEA
Page 79 and 80: ADULT HEART TRANSPLANTATION % OF PA
Page 81 and 82: % of transplants 40 35 30 25 20 15
Page 83 and 84: 2. Januar 2012 Lebensqualität 10 J

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