Primary FRCA exam January 2010

Primary FRCA exam January 2010arthroscopy. Unwilling to have op postponed. Convince him!PHARMACOLOGY:They started all the vivas gently but they got harder asthe 15 minutes went on and the pace was really fast so ifyou said you didnt know something they moved on. I didfeel that the questions were repeated rather than asked ina different way.1. They asked me to talk about the mechanism of action ofNSAID. They wanted the pathways drawn from arachidonicacid and all the end products and enzymes involved.What is the difference between COX1 and COX2 when do theyact?Why do we want selective inhibitors? What problems werefound in their use?What does each product of the COX reaction so and where?Asked about types of prostaglandins and the side effectsof their production being inhibited.2. Cholinergic receptors and their agonists. Whatmuscarinic receptor types exist and where are theypresent? What agonists do you know? What antagonists doyou know? When are they used in anaesthesia? Whateffects do they have? we talked about teritary andquaternary structures and the BBB.Otheres were asked to draw the muscarinic receptor. Iwas asked about organophosphates and then briefly abouttheir action and effects.3. Colloids, what are they and what types exist and whyare they useful? Which ones are in my hospital and whattypes they are. I was then asked to compare gelatincolloids from starch colloids. Where and how each aremetabolised. Why do colloids stay in the intravascularspace. What happens when they are infused. Describe theideal colloid or intravenous fluid. What are the sideefffects or complications of their use.27