Current and Future Skin Permeation Technologies for Drug Delivery

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Permeation Enhancers‣Chemical Permeation Enhancers‣ High boiling alcohols‣ Diols‣ Fatty acids and Fatty acid esters‣ Oleic acid‣ Glyceride-based solvents
Macrochem(www.macrochem.com)SEPA® drug delivery technologyQuickTime and aTIFF (Uncompressed) decompressorare needed to see this picture.NexMed(www.nexmed.com)QuickTime and aTIFF (Uncompressed) decompressorare needed to see this picture.SEPA enhances transdermal drugdelivery by temporarily andreversibly disrupting the alignmentof the lipid bilayer within the lipid.NexACT technology utilizes highlyeffective formulations containing newbiodegradable ingredients.
Page 1 and 2: Current and Future SkinPermeation T
Page 3 and 4: TRANSDERMAL BASICSQuickTime and aTI
Page 5 and 6: Routes of Penetration1. Directly ac
Page 7 and 8: Active Transdermal Delivery
Page 9 and 10: Principal strategies for optimizing
Page 11: Permeation Enhancers
Page 15 and 16: IontophoresisA current passed betwe
Page 17 and 18: Electrokinesis‣ Electrokinetic dr
Page 19 and 20: ElectroporationElectroporation is a
Page 21 and 22: MicroneedlesZosano Pharma(Formerly
Page 23 and 24: Thermal MethodsZars Pharma(www.zars
Page 25 and 26: TheraJect’s TheraJectMAT(www.ther
Page 27 and 28: FUTURE DIRECTIONS
Page 29 and 30: Radio Frequency EnergyTransPharma M
Page 31 and 32: Reverse Iontophoresis & Closed Loop
Page 33 and 34: Technology Hybrids and Micro Transd
Page 35: Summary‣ Transdermals are still a

Current and Future Skin Permeation Technologies for Drug Delivery

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