ICS Scientific Program PDF - 26 International Carbohydrate ...

July 22-27, 2012. 

Program 

13

SUNDAY 22 

Sunday 22 

16:00-20:00 Registration 

17:00-17:30 Room 1: Auditorium 

14 

Symposium Opening 


IUPAC Presentation: H. Vliegenthart 


Whistler Award Ceremony. Whistler Lecture. 

Empirical Approach at Understanding Glycosylation Reactions as Basis 

for Automated Oligosaccharide Synthesis 

P. Seeberger (Berlin), Max-Planck Institute For Colloids And Interfaces 

Chair: B. Smestad Paulsen (Oslo) 


Plenary 1 

Synthetic Challenges and Research Opportunities Around 

Glycoconjugates 

Y. Ito (Wako-Saitama), RIKEN Advanced Science Institute 

Chair: G. Davies (York) 

20:00 Welcome Cocktail 

Madrid, Spain

Monday 23 


July 22-27, 2012. 

Plenary 2 

Heparin: Structure, Activity and Synthesis 

R. Linhardt (Troy), Rensselaer Polytechnic Institute 

Chair: M. Martín-Lomas (San Sebastián) 


Plenary 3 

(Poly)Sialoglycotopes in Organogenesis 

R. Gerardy-Schahn (Hannover), Institute For Cellular Chemistry, Hannover 

Medical School 

Chair: B. Davis (Oxford) 

10:00-11:00 Coffee-Posters 


Session 01. Synthesis: Methods and Applications 

INV. 01. Synthetic Glycochemistry: Controlling Selectivity with Iron Salts 

J. M. Beau (Orsay), Institut De Chimie Moleculaire Et Des Materiaux D’Orsay. 

11:00-11:30 Room 3: Hidalgo 

Chairs: P. Kosma (Vienna), V. Vérez Bencomo (La Habana) 

Session 02. Diseases and Therapeutics, Glycomedicine 

INV. 02. Congenital Disorders of Glycosylation (CDG): a booming disease 

family 

J. Jaeken (Leuven), University Hospital Gasthuisberg. 

Chairs: T. Endo (Tokyo), T. Baasov (Haifa) 

11:00-11:30 Room 2: Castilla 

Session 03. Synthesis in glycosciences 

INV. 03. GAGomic: Synthetic Tricks and Mimetics for Analytics and 

Futur(istic) Therapeutics. 

D. Bonnaffé (Orsay Cedex), Université Paris Sud 

Chairs: L.Somsak (Debrece), S. Jarosz (Warsaw) 

15 

MONDAY 23

MONDAY 23 

11:00-11:30 Room 4: Doblón 

16 

Session 04. Structure and Molecular Recognition 

INV. 04. From lectin structure to functionality: the sugar code at work 

H. J. Gabius (Munich), Ludwig-Maximilians-University Munich 

Chairs: D. Solis (Madrid), V. Kren (Prague) 

11.30-13.00 Room 1: Auditorium 

Session 01. Synthesis: Methods and Applications. 

ORAL (Young Investigator) 

O01 

REACTION OF OXATHIANE GLYCOSYL DONORS WITH DIPHENYL 

SULFOXIDE-TRIFLIC ANHYDRIDE: THE MECHANISM OF AN 

UNEXPECTED OXIDATION REACTION 

Turnbull, W. B. 1 ; Fascione, M. A. 1 ; Adshead, S. J. 1 ; Mandal, P. K. 1 ; Kilner, C. 

A. 1 Leach, A. G. 2 

1 School of Chemistry, University of Leeds, Leeds, UNITED KINGDOM 

2 AstraZeneca, Alderley Park, Macclesfi eld, Cheshire, UNITED KINGDOM 

O02 

SYNTHESIS AND APPLICATION OF PLANT CELL WALL 

OLIGOSACCHARIDES 

Clausen, Mads 

Technical University of Denmark, DENMARK 

O03 

NOVEL SYNTHETIC TOOLS FOR GLYCOBIOLOGY 

Galan, M. Carmen 

School of Chemistry, University of Bristol, UNITED KINGDOM 

O04 

CARBENE-MEDIATED FUNCTIONALIZATION OF THE ANOMERIC C-H 

BOND OF CARBOHYDRATES: SCOPE, LIMITATIONS AND MECHANISTIC 

INSIGHTS 

Lecourt, Thomas 1 ; Boultadakis-Arapinis, Mélissa1 ; Micouin, Laurent 1 ; Turcaud, 

Serge1 ; Prost, Elise 2 ; Lemoine, Pascale 3 

1 Université Paris Descartes-CNRS UMR 8601, FRANCE 



O05 

GENERATION OF GLYCOSYL CATION EQUIVALENTS USING 

ELECTROCHEMICALLY GENERATED ArS(ArSSAr)X 

Nokami, Toshiki; Saito, Kodai; Yoshida, Jun-ichi 

Kyoto University, JAPAN 

Madrid, Spain

July 22-27, 2012. 

O06 

STEREOCOMPLEMENTARY ROUTES TO HYDROXYLATED NITROGEN 

HETEROCYCLES 

Parmeggiani, Camilla 1,2,3 ; Cardona, Francesca2 ; Reissig, Hans-Ulrich 3 ; 

Goti, Andrea 2 

1 Consiglio Nazionale delle Ricerche-Istituto Nazionale di Ottica, 

CNR-INO, ITALY 

2 Department of Chemistry ‘Ugo Schiff’, University of Florence, ITALY 

3 Institute für Chemie und Biochemie, Freie Universität Berlin, GERMANY 

11.30 -13.00 Room 3: Hidalgo 



O07 

PARTNERSHIP AMONGST FAMILIES, RESEARCHERS AND PHYSICIANS 

TO DECIPHER CONGENITAL DISORDERS OF GLYCOSYLATION (CDG)’. 

Dos Reis Ferreira, Vanessa Miriam; Félix, Rosália 

Portuguese Association for Congenital Disorders of Glycosylation and Other 

Rare Metabolic Diseases, PORTUGAL 

O08 

ENDOTHELIAL N-GLYCAN MANNOSE RESIDUES MEDIATE MONOCYTE 

ADHESION UNDER FLOW 

Scott, David 1 ; Chen, Jie2 ; Chacko, Balu 1 ; Traylor Jr., James 2 ; Orr, A. Wayne 2 ; 

Patel, Rakesh 1 

1 University of Alabama at Birmingham, USA 

2 Louisiana State University Health Science Center, USA 

O09 

PROKARYOTIC CELL WALL GLYCOCONJUGATES AS KEY MEDIATORS 

IN THE INTERACTION WITH EUKARYOTIC HOST 

Marchetti, Roberta; Lanzetta, Rosa; Silipo, Alba; Molinaro, Antonio 

University of Naples “Federico II”, ITALY 

O10 

PHOTODEGRADATION OF TARGET GLYCOLIPID LPS AND INHIBITION 

OF MACROPHAGE ACTIVATION BY ANTHRAQUINONE-BORONIC ACID 

HYBRIDS 

Takahashi, Daisuke; Miura, Takuya; Toshima, Kazunobu 

Department of Applied Chemistry, Faculty of Science and Technology, Keio 

University, JAPAN 

17 

MONDAY 23

MONDAY 23 

18 

O11 

THE 3-D STRUCTURE OF Thermotoga neapolitana β-GLUCOSIDASE 1A 

AND THE INFLUENCE OF SINGLE MUTATIONS ON THE ACTIVITY USING 

SELECTED CARBOHYDRATE SUBSTRATES 

Kulkarni, Tejas 1 ; Khan, Samiullah1 ; Mahmood, Tahir 1 ; Ara, Kazi Zubaida 

Gulshan 1 ; Pozzo, Tania 1 ; Logan, Derek 2 ; Nordberg Karlsson, Eva 1 

1 Biotechnology, Department of Chemistry, Lund University, SWEDEN 

2 Biochemistry and Structural Biology, Department of Chemistry, Lund University, 

SWEDEN 

O12 

IN VITRO MANNOSE-TRIMMING PROPERTIES OF HUMAN ER ALPHA-1,2 

MANNOSIDASE I 

Aikawa, Jun-Ichi 1 ; Takeda, Yoichi2 ; Matsuo, Ichiro 3 ; Ito, Yukishige 1,2 

1 RIKEN Advanced Science Institute, JAPAN 

2 ITO Glycotrilogy Project, ERATO, JST JAPAN 

3 Graduate School of Engineering, Gunma University, JAPAN 

11.30-13.00 Room 2: Castilla 

Session 03. Synthesis in Glycosciences 

ORAL. 

O13 

TARGETING THE HEPTOSE BIOSYNTHETIC PATHWAY FOR THE 

DISCOVERY OF ANTIVIRULENCE AND ANTIBACTERIAL AGENTS 

Vincent, Stéphane 

University of Namur, BELGIUM 

O14 

STUDIES OF 1,2-UNSATURATED SUGARS THROUGH EXPANSIONS, 

SHIFTS AND REARRANGEMENTS 

Jayaraman, N.; Paul, S.; Ganesh, N. V.; Mukherji, A.; Daskhan, G. C. ; Dey, S. 

Indian Institute of Science, Bangalore, INDIA 

O15 

FORMATION AND REACTIVITY OF NEW FERRIER-NICHOLAS 

PYRANOSIDIC CATIONS 

Lobo, Fernando; López, J. Cristóbal; Miranda, Silvia; Gómez, Ana M. 

Instituto de Química Orgánica General, CSIC, SPAIN 

O16 

NICKEL-CATALYZED STEREOSELECTIVE SYNTHESIS OF 

1,2-CIS-2-AMINOSUGARS 

Nguyen, Hien 

University of Iowa, USA 

O17 

QUANTITATIVE GLYCOSYLATION TECHNOLOGY FOR LARGE 

SCALE SYNTHESIS (POTENTIAL COMMERCIAL SCALE) OF 

OLIGOGLUCOSAMINES 

Sabesan, Subramaniam; Spado, Christina 

DuPont Company, USA 

Madrid, Spain

July 22-27, 2012. 

O18 

SYNTHESIS OF ALPHA-GALACTOSYL EPITOPES BY METABOLICALLY 

ENGINEERED Escherichia coli. 

Mialy, Randriantsoa 2 ; Caroline, Gebus1 ; Sophie, Drouillard 1 ; Eric, Samain 1 ; 

Claire, Cottin 2 

1 CERMAV-CNRS, FRANCE 

2 Elicityl, FRANCE 

11.30-13.00 Room 4: Doblón 


ORAL. 

O19 

FIRST EXAMPLE OF NMR ANALYSIS WITH NON-LABELLED ROUGH- 

TYPE LPS IN WATER 

Zähringer, Ulrich 1 ; Ittig, Simon2 ; Lindner, Buko 1 ; Gisch, Nicolas 1 ; 

Cornelis, Guy 2 

1 Research Center Borstel, Borstel, GERMANY 

2 Biozentrum Basel, SWITZERLAND 

O20 

STUDIES ON THE MOLECULAR RECOGNITION OF AMINOGLYCOSIDE 

ANTIBIOTICS BY RNA AND RESISTANCE ENZYMES 

Asensio Álvarez, Juan Luis 

Instituto de Química Orgánica General, CSIC, SPAIN 

O21 

COMPUTATIONAL DESIGN OF HIGH-AFFINITY GLYCOMIMETIC 

INHIBITORS FOR FLEXIBLE LECTINS 

Frank, Martin 1 ; Prescher, Horst2 ; Brossmer, Reinhard 2 

1 Biognos AB, SWEDEN 

2 Glyco Medical Research GmbH, 

O22 

STRUCTURAL ANALYSIS OF VIRUS FIBRE BINDING TO CARBOHYDRATES 

Van Raaij, Mark J 

Centro Nacional de Biotecnología CSIC, Madrid, SPAIN 

O23 

STRUCTURE-BASED DESIGN OF NEW ANTIBIOTICS BY INHIBITION OF 

THE SHIKIMIC ACID PATHWAY 

González-Bello, Concepción; Peón, Antonio; Tizón, Lorena; Blanco, Beatriz; 

Sedes, Antía; Lence, Emilio 

CIQUS, Universidad de Santiago de Compostela, SPAIN 

19 

MONDAY 23

MONDAY 23 

20 

O24 

DIVERGENCES IN MOLECULAR PROPERTIES AND BINDING SELECTIVITY 

OF GALECTINS WITH TANDEM-REPEAT DISPLAY: A CASE STUDY ON 

HUMAN GALECTINS 4 AND 8. 

Buzamet, Eliza 1,2 ; Ruiz, Federico M. 3 ; Kaltner, Herbert 4 ; André, Sabine 4 ; 

Romero, Antonio 3 ; Gabius, Hans-Joachim 4 ; Menéndez, Margarita 1,2 ; Solís, 

Dolores 1,2 

1 Instituto de Química Física Rocasolano, CSIC, Madrid, SPAIN 

2 Centro de Investigación Biomédica en Red de Enfermedades Respiratorias 

(CIBERES), Bunyola, Mallorca, Illes Balears, SPAIN 

3 Centro de Investigaciones Biológicas, CSIC, Madrid, SPAIN 

4 Institut für Physiologische Chemie, LMU München, GERMANY 



FLASH (Young Investigator) 

F01 

UNSATURATED NEURAMINIC ACID DERIVATIVES: SYNTHESIS AND 

ALLYLIC SUBSTITUTION MECHANISM STUDIES 

Agnolin, Irene Sofi a; Rota, Paola; Gregorio, Antonio; Allevi, Pietro; Anastasia, 

Mario 

University of Milan, ITALY 

F02 

COPPER (II) TRIFLATE: A VERSATILE CATALYST FOR THE ONE-POT 

PREPARATION OF ORTHOGONALLY PROTECTED GLYCOSIDES 

Jones, Rachel 1 ; Tran, Anh-Tuan1 ; Pastor, Julien 1 ; Boisson, Julien 1 ; Smith, 

Nichola 2 ; Galán, Carmen 1 

1 University of Bristol, UNITED KINGDOM 

2 Novartis Institutes of Biomedical Research, UNITED KINGDOM 

F03 

4-(2-CHLOROETHOXY)PHENYL GLYCOSIDES IN THE SYNTHESIS OF 

PGL-1 NEOGLYCOCONJUGATES 

Kondakov, Nikolay; Melnikova, Tatiana; Zinin, Alexander; Torgov, Vladimir; 

Kononov, Leonid 

N.D. Zelinsky Institute of Organic Chemistry of RAS, RUSSIA 

F04 

DIASTEREOSELECTIVITY OF CONFORMATIONALLY ARMED 

RHAMNOSYL DONORS 

Marcus Pedersen, Christian; Heuckendorff, Mads; Bols, Mikael 

University of Copenhagen, DENMARK 

F05 

REGIOSELECTIVE MONODEPROTECTION OF PERACETYLATED 

CARBOHYDRATES: A TOOL-KIT IN CARBOHYDRATE CHEMISTRY 

Palomo, Jose Miguel; Filice, Marco 

Institute of Catalysis CSIC, Madrid, SPAIN 

Madrid, Spain

July 22-27, 2012. 

F06 

A NEW TYPE OF SIALYL DONORS: O-TRIFLUOROACETYL DERIVATIVES 

Podvalnyy, Nikita; Malysheva, Nelly 1 ; Zinin, Alexander; Kononov, Leonid 

N.D. Zelinsky Institute of Organic Chemistry, RUSSIA 

13.00-13.30 Room 3: Hidalgo 



F07 

ANTIGEN-SPECIFIC B CELL TOLERANCE MEDIATED BY SIGLECS 

Pfrengle, Fabian; Macauley, Matthew S.; Paulson, James C. 

The Scripps Research Institute, USA 

F08 

PURIFICATION AND CHARACTERIZATION OF A LECTIN FROM Lepechinia 

bullata SEEDS 

Wilches, Andrea 

Universidad Nacional de Colombia, Bogotá, COLOMBIA 

F09 

BIVALENT CARBOHYDRATE-BINDING PROPERTY OF CNL, 

A GalNAcβ1-4GlcNAc-SPECIFIC LECTIN FROM BASIDIOMYCETE 

Clitocybe nebularis, IS REQUIRED FOR ITS BIOLOGICAL ACTIVITY 

Pohleven, Jure 1 ; Renko, Miha2 ; Sabotič, Jerica 1 ; Magister, Špela 1 ; Turk, 

Dušan 2 ; Kos, Janko 1,3 

1 Department of Biotechnology, Jožef Stefan Institute, SLOVENIA 

2 Department of Biochemistry and Molecular and Structural Biology, Jožef 

Stefan Institute, SLOVENIA 

3 Faculty of Pharmacy, University of Ljubljana, SLOVENIA 

F10 

REGULATION OF A VACUOLAR INVERTASE ON THE POST 

TRANSLATIONAL LEVEL VIA A PROTEINACEOUS INHIBITOR IN 

Solanum lycopersicum 

Tauzin, Alexandra 1 ; Sulzenbacher, Gerlind2 ; Lafond, Michael 3 ; Reca, Ida 

Barbara 4 ; Lévêque, Christian 5 ; Bellincampi, Daniela 6 ; Giardina, Thierry 1 

1 Faculté des Sciences et Techniques Saint-Jérôme, Aix-Marseille Université, 

Pôle de l’Etoile, ISM2/BiosCiences UMR CNRS7313, Marseille, FRANCE 

2 Architecture et Fonction des Macromolécules Biologiques UMR CNRS 7257, 

Université Aix-Marseille, Pôle de Luminy, Marseille, FRANCE 

3 Laboratoire de Biotechnologie des Champignons Filamenteux UMR INRA 

1163, Aix-Marseille Université-ESIL Polytech, Pôle de Luminy, Marseille, 

FRANCE 

4 Great Lakes Bioenergy Research Center, Michigan State University, USA 

5 CAPM/Biocapteurs, Institut Jean Roche, Aix Marseille Université, Faculté de 

Médecine secteur nord, Bd P. Dramard, Marseille, FRANCE 

6 Dipartimento di Biologia e Biotecnologia ‘C. Darwin’, Università di Roma La 

Sapienza, Roma, ITALY 

21 

MONDAY 23

MONDAY 23 

22 

F11 

SYNTHESIS OF MUCIN CORE 1-4 OLIGOSACCHARIDES READY FOR 

PLATFORM IMMOBILISATION 

Benito Alifonso, David; Galán Hurtado, Mª Carmen 

University of Bristol, UNITED KINGDOM 

F12 

α-GALACTOSIDASE / SUCROSE KINASE (AgaSK), A NOVEL 

BIFUNCTIONAL ENZYME FROM THE HUMAN MICROBIOME. 

Bruel, Laetitia 1 ; Sulzenbacher, Gerlind1 ; Cervera Tison, Marine 1 ; Pujol, Ange 

1 1 1 2 1 ; Perrier, Josette ; Galinier, Anne ; Ropartz, David ; Fons, Michel ; Pompéo, 

Frédérique 1 ; Giardina, Thierry 1 

1 CNRS, Marseille, FRANCE 

2 INRA, FRANCE 


Session 03. Synthesis in Glycosciences 

FLASH 

F13 

FIFTY FIVE STEP SYNTHESIS OF DEFINED 12-MER FRAGMENTS OF 

HEPARAN SULFATE 

Zubkova, Olga 1 ; Schwörer, Ralf1 ; Tyler, Peter 1 ; Turnbull, Jeremy 2 

1 Industrial Research Ltd, NEW ZEALAND 

2 University of Liverpool, UNITED KINGDOM 

F14 

KINETIC ANALYSIS FOR ALTERNATIVE ELONGATION OF 

GLYCOSAMINOGLYCANS CATALYZED BY GLYCOSYLTRANSFERASE 

USING QCM AND AFM. 

Mori, Toshiaki 1 ; Hirose, Atsushi1 ; Ohtsuka, Masanori 1 ; Hagiwara, Tatsuya 1 ; 

Sugiura, Nobuo 2 ; Kimata, Koji 2 ; Kakuta, Yoshimitsu 3 ; Okahata, Yoshio 1 

1 Tokyo Institute of Technology, JAPAN 

2 Aichi Medical University, JAPAN 

3 Kyushu University, JAPAN 

F15 

S-BENZIMIDAZOLYL GLYCOSIDES AS A NEW PLATFORM FOR 

EXPEDITIOUS OLIGOSACCHARIDE ASSEMBLY 

Hasty, Scott; Demchenko, Alexei 

University of Missouri-St. Louis, USA 

F16 

SYNTHESIS, STRUCTURAL CHARACTERIZATION AND IMMUNOLOGICAL 

PROPERTIES OF MYCOBACTERIAL GLUCUROSYL DIACYLGLYCERIDES 

Williams, Spencer; Cao, Benjamin; Richardson, Mark 

University of Melbourne, AUSTRALIA 

Madrid, Spain

July 22-27, 2012. 

F17 

SYNTHESIS OF NEW CARBOHYDRATE-BASED PYRIDINIUM SALTS AS 

POTENTIAL FLUORESCENT PROBES 

Franconetti, Antonio; Contreras, Lidia; Gómez Guillén, Manuel; Jatunov, Sorel; 

Cabrera Escribano, Francisca 

University of Seville, SPAIN 

F18 

A ONE-POT CHEMICAL SYNTHESIS OF SUGAR NUCLEOSIDE 

DIPHOSPHATES IN WATER 

Tanaka, Hidenori; Yoshimura, Yayoi; Palcic, Monica; Ole, Hindsgaul 

Carlsberg Laboratory, Copenhagen, DENMARK 

13.00 -13.30 Room 4: Doblón 



F19 

ORGANOCATALYTIC SYNTHESIS OF CARBOHYDRATES 

Mlynarski, Jacek 

Jagiellonian University, POLAND 

F20 

INSIGHT THE INTERACTION BETWEEN BLOOD GROUP DETERMINANTS 

AND CHOLERA TOXIN: OPPORTUNITY TO DESIGN A NEW CLASS OF 

CHOLERA TOXIN ANTAGONISTS 

Reina, José Juan 1 ; Vasile, Francesca1 ; Heggelund, Julie E. 2 ; Rusconi, Giulia 1 ; 

Potenza, Donatella 1 ; Krengel, Ute 2 ; Bernardi, Anna 1 

1 Dipartimento di Chimica, Universitá Degli Studi Di Milano, Milano, ITALY 

2 Department of Chemistry, University of Oslo, Oslo, NORWAY 

F21 

DISTINCT BINDING MODES FOR SUBSTITUTED LEWIS STRUCTURES TO 

DC-SIGN 

Mayer, Katharina; Scharenberg, Meike; Eid, Sameh; Cutting, Brian; Rabbani, 

Said; Ernst, Beat 

University of Basel, SWITZERLAND 

F22 

THE INVOLVEMENT OF IgG-Fc-CONJUGATED GLYCANS IN 

AMYOTROPHIC LATERAL SCLEROSIS DISEASE 

Edri-Brami, Meital 1 ; Offen, Danny2 ; Lichtenstein, Rachel 1 

1 Ben-Gurion University of The Negev, ISRAEL 

2 Tel Aviv University, ISRAEL 

23 

MONDAY 23

MONDAY 23 

13.30-15.00 LUNCH 

24 

F23 

TRANSGENIC SILKWORM AS A NOVEL THERAPEUTIC GLYCOENZYME 

RESOURCE FOR LYSOSOMAL STORAGE DISEASES 

Itoh, Kohji 1,5 ; Nishioka, So-ichiro1,5 ; Tsuji, Daisuke 1,5 ; Maita, Nobuo 2 ; Kobayashi, 

Isao 3,5 ; Sezutsu, Hideki 3,5 ; Harazono, Kei 4 ; Ishii, Akiko 4 ; Kawasaki, Nana 4 ; 

Machii, Hiroaki 3,5 

1 Dept. of Medicin. Biotechnol., Inst. for Medicin. Res., Grad. Schl. of 

Pharmaceut. Sci., The Univ. of Tokushima, Tokushima, JAPAN 

2 Div. of Struct. Biol., Inst. of Enzyme Res., The Univ. of Tokushima, Tokushima, 

JAPAN 

3 Transgenic Silkworm Res. Centr., Natl. Inst. of Agrobiol. Sci.,Tsukuba, JAPAN 

4 Div. of Biol. Chem. Biologicals, Natl. Inst. of Health Sci., Tokyo, JAPAN 

5 Agri-health Translational Res. PT, Tokyo, JAPAN 

F24 

INVESTIGATION OF EFFECTS OF Sep15 ON GLYCOSYLTRANSFERASE 

ACTIVITY OF THE FOLDING SENSOR PROTEIN UGGT1 

Kanamori, Akiko 1 ; Takeda, Yoichi1 ; Seko, Akira 1 ; Ito, Yukishige 1,2 

1 ERATO EJapan Socience and Technology Agency(JST), JAPAN 

2 RIKEN EAdvanced Science Institute (ASI), JAPAN 



INV. 05. Highly Stereoselective Glycosylation and Its Application 

X. Liu (Singapore), Nanyang Technological University 


Chairs: N. Jayraman (Bangalore), T. Lowary (Edmonton) 

Session 06. Glycobiology and Glycomedicine 

INV. 06. Role of protein O-mannosylation in congenital muscular 

dystrophies 

T.Endo (Tokyo), Tokyo Metropolitan Institute Of Gerontology 

Chairs: Y. Ito (Saitama), T.Stehle (Tuebingen) 

15:00-15:30 Room 3: Hidalgo 

º Session 07. Lilly Session 

INV. 07. Three-dimensional interpretation of heparan sulfate sequences 

B. Mulloy (Potters Bar), Nibsc 

Chairs: B. M. Pinto (Burnaby), J.Thiem (Hamburg) 

Madrid, Spain

15:00-15:30 Room 4: Doblón 

July 22-27, 2012. 

Session 08. Glycomaterials 

INV. 08. Novel polysaccharide architectures: Chain compaction and 

hyperbranching 

B. J. Christensen (Trondheim), Norwegian University Of Science And 

Technology (NTNU) 

Chairs: M.J. Hernáiz (Madrid), Serge Pérez (Grenoble) 



ORAL 

O25 

REVERSE ORTHOGONAL APPROACH TOWARDS THE ONE-POT 

SYNTHESES OF BRANCHED MANNO-OLIGOMERS; COMBINING 

REGIOSELECTIVE REDUCTIVE CLEAVAGE OF BENZYLIDENE ACETALS/ 

SILYL ETHERS AND GLYCOSYLATION. 

Sen, Asish; Sarkar, Swarbhanu; Dutta, Samrat; Pal, Rammyani 

Indian Institute of Chemical Biology, INDIA 

O26 

MODULATING GLYCOSYLATION APPROACH FOR PARTICIPATING 

THIOGLYCOSYL DONORS 

Mong, Kwok-Kong Tony 

National Chiao Tung University, TAIWAN 

O27 

NEW DEVELOPMENTS IN SIALYLATION REACTIONS 

de Meo, Cristina 1 ; Gobble, Chase1 ; Pornsuriyasak, Papapida 2 ; Demchenko, 

Alexei V. 2 

1 Southern Illinois University Edwardsville, USA 

2 University of Missouri-St. Louis, USA 

25 

MONDAY 23

MONDAY 23 



ORAL 

O28 

N-LINKED PROTEIN GLYCOSYLATION IN THE CYTOPLASM OF 

Escherichia coli: A NOVEL ROUTE TO N-GLYCOPROTEINS 

Nägeli, Andreas 1 ; Schwarz, Flavio1 ; Fan, Yao-Yun 1 ; Schubert, Mario 2 ; Papini, 

Anna Maria 3 ; Aebi, Markus 1 

1 ETH Zürich, Institute of Microbiology, Department of Biology, SWITZERLAND 

2 ETH Zürich. Institute of Molecular Biology and Biophysics, Department of 

Biology, SWITZERLAND 

3 Università di Firenze. Laboratorio di Chimica e Biologia di Peptidi e Proteine, 

Polo Scientifi co e Tecnologico, ITALY. 

26 

O29 

A NOVEL MARKER ANTIBODY OF HUMAN INDUCED PLURIPOTENT 

STEM (iPS) CELLS, WHICH RECOGNIZES A NEW TYPE OF KERATAN 

SULFATE 

Kawasaki, Toshisuke 1 ; Kawabe, Keiko1,2 ; Kusuda Furue, Miho 2 ; Nakao, 

Hiromi 1 ; Matsumoto, Shogo 1 ; Nonaka, Motohiro 1 ; Toyoda, Hidenao 3 ; Hirose, 

Yoshinori 3 ; Kawasaki, Nana 4 ; Kawasaki, Nobuko 1 

1 Research Center for Glycobiotechnology, Ritsumeikan University, JAPAN 

2 Department of Disease Bioresources, National Institute of Biomedical 

Innovation 

3 Faculty of Pharmaceutical Sciences, Ritsumeikan University, JAPAN 

4 Division of Biological Chemistry and Biologicals, National Institute of Health 

Sciences 

O30 

THE GLYCOSYLATED CELL ENVELOPE OF Tannerella forsythia 

Schäffer, Christina 1 ; Posch, Gerald1 ; Pabst, Martin 2 ; Brecker, Lothar 3 ; Sekot, 

Gerhard 1 ; Friedrich, Valentin 1 ; Altmann, Friedrich 2 ; Messner, Paul 1 

1 Universität für Bodenkultur Wien, Department für NanoBiotechnologie, 

AUSTRIA 

2 Universität für Bodenkultur Wien, Department für Chemie, AUSTRIA 

3 Universität Wien, Institut für Organische Chemie, AUSTRIA 

Madrid, Spain

15.30-16.15 Room 3: Hidalgo 

Session 07. Lilly Session 


O31 

SYNTHETIC GOLD GLYCONANOPARTICLES INDUCE AN 

IMMUNOSUPPRESIVE STATE ON DENDRITIC CELLS 

Chiodo, Fabrizio 1 ; García-Vallejo, Juan Jesus2 ; Marradi, Marco 1,3 ; Bruijns, 

Sven 2 ; Penadés, Soledad 1,3 ; van Kooyk, Yvette 2 

1 CIC BiomaGUNE, SPAIN 

2 Department of Molecular Cell Biology & Immunology, VU University Medical 

Center, Amsterdam, THE NETHERLANDS 

3 Networking Research Centre on Bioengineering, Biomaterials and 

Nanomedicine (CIBER-BBN), San Sebastián, SPAIN 

O32 

IN VIVO TARGETING OF MACROPHAGES USING SIALOSIDE ANALOGS 

Rademacher, Christoph 1, 2 ; Nycholat, Corwin M. 2 ; Kawasaki, Norihito 2 ; Chen, 

Weihsu C. 2 ; Paulson, James C. 2 

1 Max Planck Institute of Colloids and Interfaces, Department of Biomolecular 

Systems, GERMANY 

2 The Scripps Research Institute, Department of Chemical Physiology, La Jolla, 

USA 

O33 

BINDSCAN-A NEW COMPUTATIONAL ALGORITHM TO IDENTIFY ENZYME 

POSITIONS SENSIBLE TO THE BINDING OF NEW SUBSTRATES. 

Biarnés, X.; Aragunde, H; Andrés, E.; Planas, A. 

Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull, 

Barcelona, SPAIN 

15.30-16.15 Room 4: Doblón 

July 22-27, 2012. 

Session 08. Glycomaterials 


O34 

THE PRINCIPLE OF STARCH RETROGRADATION 

Tako, Masakuni; Shimabukuro, Jyunpei; Konishi, Teruko 

Department of Subtropical Bioscience and Biotechnology, University of The 

Ryukyus, JAPAN 

O35 

EFFECT OF LIGNIN ON THE ENZYMATIC HYDROLYSIS OF CELLULOSE 

NANOFIBRILS AND FILMS. 

Martin-Sampedro, Raquel 1 ; Hoeger, Ingrid2 ; Filpponen, Ilari 1 ; Laine, Janne 1 ; 

Rojas, Orlando 1,2 

1 Department of Forest Products Technology, Aalto University, FINLAND 

2 Department of Forest Biomaterials, North Carolina State University, USA 

27 

MONDAY 23

MONDAY 23 

28 

O36 

COMPATIBILIZER EFFECT OF TARTARIC ACID IN STARCH/POLYESTER 

BLOWN FILMS 

Grossmann, Maria; Olivato, Juliana; Bilck, Ana; Yamashita, Fabio 

Universidade Estadual de Londrina, BRAZIL 

16.15-17.00 Coffee - Posters 



INV. 09. Oligosaccharide Synthesis by Donor Preactivation Protocol 

X. S. Ye (Beijing), State key Laboratory of Natural and Biomimetic Drugs, 

Peking University 

Chairs: S. Flitsch (Manchester), T. Lindhorst (Kiel) 


Session 10 Glycobiology and Glycomedicine 

INV. 10. To fi x nature’s mistakes: repairing human faulty genesby sugarsbased 

small molecules 

T. Baasov (Haifa), Technion - Israel Institute Of Technology 

Chairs: D. Whitfi eld (Ontario), T. Kawasaki (Kusatsu) 

17:00 - 17:30 Room 3: Hidalgo 

Session 11 Glycosaminoglycans 

INV. 11. Chemical Biology of Heparan Sulfates – from Insights to 

Applications 

J. Turnbull (Liverpool), University Of Liverpool 

Chairs: P.A. Driguez (Chilly-Mazarin), B. Mulloy (Potters Bar) 

17:00 - 17:30 Room 4: Doblón 

Session 12 Glycobiology and Molecular Recognition 

INV. 12. Glycomics and drug discovery 

S. I. Nishimura (Sapporo), Hokkaido University 

Chairs: M.Gurjar (Pune), M. J. Camarasa (Madrid) 


INV. 09. Session 09. Synthesis: Methods and Applications 


O37 

REDUCING THE CONFORMATIONAL FLEXIBILITY OF CARBOHYDRATES 

BY CYCLOPROPANE UNITS 

Werz, Daniel B.; Brand, Christian 

University of Göttingen, Institute of Organic and Biomolecular Chemistry, 

GERMANY 

Madrid, Spain

July 22-27, 2012. 

O38 

REGIOSELECTIVITY AMONG SIX SECONDARY HYDROXYL GROUPS: 

SELECTIVE ACYLATION OF THE LEAST REACTIVE HYDROXYL GROUPS 

OF INOSITOL 

Sureshan, Kana M.;Vibhute, Amol M. 

Indian Institute of Science Education and Research, Thiruvananthapuram, 

INDIA 

O39 

CATALYST-CONTROLLED REGIOSELECTIVE PROTECTION AND 

GLYCOSYLATION OF CARBOHYDRATE DERIVATIVES 

Taylor, Mark S. 

Department of Chemistry, University of Toronto, CANADA 

O40 

SYNTHESIS OF AZASUGARS VIA IODOCYCLISATION: MECHANISTIC 

INVESTIGATIONS 

Timmer, Mattie 1 ; Win-Mason, Anna1,2 ; Stocker, Bridget 2 

1 Victoria University Wellington, NEW ZEALAND 

2 Malaghan Institute of Medical Research, NEW ZEALAND 




O41 

TOWARDS CELL CULTURE-BASED INFLUENZA VACCINE DESIGN: 

IMPACT OF VIRAL HEMAGGLUTININ N-GLYCOSYLATION ON 

IMMUNOGENICITY 

Hütter, Julia 1 ; Rödig, Jana2 ; Reichl, Udo 2 ; Seeberger, Peter 1 ; Rapp, Erdmann 

2 1 

; Lepenies, Bernd 

1 Max Planck Institute of Colloids and Interfaces, GERMANY 

2 Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, 

GERMANY 

O42 

MECHANISTIC INSIGHTS INTO THE RETAINING GT-A GLUCOSYL-3- 

PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIA 

Guerin, Marcelo 

Unit of Biophysics, SPAIN 

O43 

LACTOBACILLUS AND BIFIDOBACTERIAL LECTINS INTERACTING TO 

GLYCOCONJUGATES: SIMILARITIES AND DIFFERENCES 

Lakhtin, Mikhail; Lakhtin, Vladimir; Alyoshkin, Vladimir; Afanasyev, Stanislav 

G.N. Gabrichevsky Research Institute For Epidemiology & Microbiology, 

RUSSIA 

29 

MONDAY 23

MONDAY 23 

30 

O44 

NMR BINDING STUDY OF OLIGO/POLISIALIC ACID ANTIBODIES; 

ELUCIDATIONS OF THE DEGREE OF POLYMERIZATION-DEPENDENT 

RECOGNITION MECHANISMS 

Hanashima, Shinya 1 ; Sato, Chihiro2 ; Tanaka, Hiroshi 3 ; Takahashi, Takashi 3 ; 

Kitajima, Ken 2 ; Yamaguchi, Yoshiki 1 

1 Structural Glycobiology Team, RIKEN, JAPAN 

2 Graduate School of Bioagricultural Sciences, Nagoya University, JAPAN 

3 Graduate School of Science and Engineering, Tokyo Institute of Technology, 

JAPAN 

17.30-18.30 Room 3: Hidalgo 

Session 11. Glycosaminoglycans 

ORAL 

O45 

SYNTHESIS OF SIMPLE HEPARANASE SUBSTRATES 

Pearson, Andrew 1 ; Kiefel, Milton2 ; Ferro, Vito 3 ; von Itzstein, Mark 2 

1 School of Medical Science, Griffi th University, Gold Coast, AUSTRALIA 

2 Institute for Glycomics, Griffi th University, Gold Coast, AUSTRALIA 

3 School of Chemistry and Molecular Biosciences, University of Queensland, 

Brisbane, AUSTRALIA 

O46 

NEW SYNTHETIC AND ANALYTICAL TOOLS FOR THE STUDY OF 

PROTEIN- GLYCOSAMINOGLYCAN COMPLEXES 

Thomas, Sarah; Hulme, Alison 

University of Edinburgh, UNITED KINGDOM 

O47 

SULFATED POLYSACCHARIDE WSS25 INHIBITS DICER TO IMPEDE 

MICRORNA-210 BY TARGETING EPHRIN-A3 TO INFLUENCE HUMAN 

MICROVASCULAR ENDOTHELIAL CELLS (HMEC-1) TUBE FORMATION 

Ding, Kan; Xiao, Fei 

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, CHINA 

O48 

OLIGOMERISATION OF LANGERIN, A C-TYPE LECTIN FROM DENDRITIC 

CELLS, IS ESSENTIAL FOR ORGANELLE ASSEMBLY, OPTIMAL HIV 

BINDING AND GLYCOSAMINOGLYCAN INTERACTION. 

Fieschi, Franck 1 ; Chabrol, Eric1 ; Thepaut, Michel 1 ; Nurisso, Alessandra 2 ; 

Daina, Antoine 2 ; Vives, Romain 1 ; Vachette, Patrice 3 ; Valladeau, Jenny 4 ; 

Durand, Dominique3 1 Institut de Biologie Structurale, Université Joseph Fourier-Grenoble, FRANCE 

2 Université de Genève, Département de Pharmacochimie, Genève, 

SWITZERLAND 

3 Institut de Biochimie et Biophysique Moléculaire et Cellulaire, Université Paris 

XI, Orsay, FRANCE 

4 Centre Léon Bérard-UMR INSERM 1052-CNRS 5286, Lyon, FRANCE 

Madrid, Spain

17.30-18.30 Room 4: Doblón 

Session 12. Glycobiology and Molecular Recognition 


O49 

HIGH AFFINITY EPITOPES OF ANTI-MUCIN 1 ANTIBODY DEVELOPED BY 

THE SYNERGY OF COMBINATORIAL CHEMISTRY AND MICROARRAY 

Garcia-Martin, Fayna 1 ; Matsushita, Takahiko1 ; Hinou, Hiroshi 1,2 ; Nishimura, 

Shin-Ichiro 1,2 

1 Graduate School of Life Science, Hokkaido University, Sapporo, JAPAN 

2 Medicinal Chemistry Pharmaceuticals LLC, N21, W12, Kita-ku, Sapporo, 

JAPAN 

O50 

CHEMICAL METHODS TO ACCESS HOMOGENEOUS FLUORINATED 

GLYCOPROTEINS 

Boutureira, Omar 1,2 ; Davis, Benjamin G. 2 

1 Universitat Rovira I Virgili, SPAIN 

2 University of Oxford, UNITED KINGDOM 

O51 

SYNTHESIS OF EXTENDED O-MANNOSE GLYCOPEPTIDES FOR 

GENERATION OF GLYCAN AND GLYCOPEPTIDE SPECIFIC ANTIBODIES 

Westerlind, Ulrika; Yu, Jin 

ISAS- Leibniz Institute for Analytical Sciences, GERMANY 

O52 

PREPARATION OF FMOC-ASN(SUGAR)-OH AND ITS COUPLING 

EFFICIENCY FOR GLYCOPEPTIDE SYNTHESIS 

Hata, Tomoya; Haneda, Katsuji; Inazu, Toshiyuki 

Tokai University, JAPAN 




F25 

APPROACHES TOWARDS THE SYNTHESIS OF HEPARIN ANALOGUES 

Sheerin, Kevin; Oscarson, Stefan 

University College Dublin, IRELAND 

F26 

NEW STRATEGIES FOR SYNTHESIS AND ASSEMBLY OF GPI ANCHORS 

AND GPI-ANCHORED PROTEINS: TOWARDS THE UNSATURATED 

SYNTHETIC GPI GLYCOLIPIDS 

Vilotijevic, Ivan 1, 2 ; Varon Silva, Daniel1, 2 1, 2 

; Seeberger, Peter 


2 Institute of Chemistry and Biochemistry, Free University of Berlin, GERMANY 

July 22-27, 2012. 

31 

MONDAY 23

MONDAY 23 

32 

F27 

BUILDING PROTEOGLYCANS FROM THE GROUND UP 

Beaudet, Julie M. 1 ; Masuko, Sayaka1 ; Yang, Bo 1 ; Sterner, Eric 1 ; Liu, Jian 2 ; 

Dordick, Jonathan S. 1 ; Linhardt, Robert J. 1 

1 Rensselaer Polytechnic Institute, USA 

2 University of North Carolina at Chapel Hill, USA 

F28 

AUTOMATED SOLID PHASE SYNTHESIS OF ANIONIC POLYSACCHARIDE 

FRAGMENTS 

Codee, Jeroen; Walvoort, Marthe; van den Elst, Hans; Volbeda, Anne-Geert; 

Overkleeft, Herman; van der Marel, Gijs 

Leiden University, NETHERLANDS 

F29 

CHEMICAL SYNTHESIS, SITE-SPECIFIC LABELLING AND BIOLOGICAL 

EVALUATION/PK OF HEPARAN SULPHATE OLIGOSACCHARIDES 

Miller, Gavin 1 ; Hansen, Steen1 ; Barath, Marek 1 ; Broberg, Karl 1 ; Avizientye, 

Egle 2 ; Cole, Claire 2 ; Rushton, Graham 2 ; Jayson, Gordon 2 ; Gardiner, John 1 

1 School of Chemistry and Manchester Interdisciplinary Biocentre, The 

University of Manchester, UNITED KINGDOM 

2 School of Cancer and Enabling Sciences, The University of Manchester, 

UNITED KINGDOM 

F31 

NITRO ALCOHOLS AS VERSATILE INTERMEDIATES IN THE SYNTHESIS 

OF CARBOHYDRATE-AZOLE CONJUGATES 

Turks, Maris; Lugiòina, Jevgeòija; Mackevièa, Jevgeòija; Rolava, Evija; Rodins, 

Vitalijs; Rjabovs, Vitâlijs 

Riga Technical University, LATVIA 

F32 

SYNTHESIS AND BIOLOGICAL ACTIVITY OF CYCLIC D-ARABINOSE 

5-PHOSPHATE MIMETICS AGAINST GRAM-NEGATIVE BACTERIA. 

Gabrielli, Luca; Merlo, Silvia; Airoldi, Cristina; Sperandeo, Paola; Scopini, 

Jessica; Polissi, Alessandra; Nicotra, Francesco; Cipolla, Laura 

University of Milano-Bicocca, Dept. of Biotechnology and Biosciences, ITALY 

F33 

ANTITUMOUR ACTIVITY OF BIS-ADDUCT OF 5-METHYLURACILE. 

Welchinska, Olena 

National Medical University of O.O. Bogomolets, UKRAINE 

Madrid, Spain


July 22-27, 2012. 



F34 

Rhizobium radiobacter RV3, A SOURCE OF MANNAN OLIGOSACCHARIDE 

WITH POTENTIAL USE AS AN HIV VACCINE DESIGN TOOL 

de Castro, Cristina1 ; Clark, Brenda2 ; Auyeung, Kate2 ; Fregolino, Eleonora1 ; 

Parrilli, Michelangelo 1 ; Lanzetta, Rosa 1 ; Pantophlet, Ralph 

1 University of Napoli, Dept. Chemical Sciences, Napoli, ITALY 

2 Faculty of Health Sciences, Burnaby, CANADA 

3 Department of Molecular Biology and Biochemistry, Simon Fraser University, 

Burnaby, CANADA 

F35 

CHEMOENZYMATIC SYNTHESIS OF MENINGOCOCCAL GROUP 

C-TETANUS HC FRAGMENT CONJUGATES 

Vann, Willie F.; McCarthy, Pumtiwitt 

CBER / FDA, USA 

F36 

IMINOSUGAR-BASED GLUCOSYLCERAMIDE ANALOGUES AS 

PHARMACOLOGICAL CHAPERONES FOR GAUCHER DISEASE 

Gallienne, Estelle 1 ; Schonemann, Wojciech1 ; Oulaidi, Farah 1 ; Compain, 

Philippe 2 ; Asano, Naoki 3 ; Ikeda-Obatake, Kyoko 3 ; Martin, Olivier 1 

1 University of Orleans & CNRS, FRANCE 

2 University of Strasbourg & CNRS, FRANCE 

3 Faculty of Pharmacy, Hokuriku University, Kanazawa, JAPAN 

F37 

SULFATIDE REGULATES PROPAGATION OF INFLUENZA A VIRUS 

THROUGH CASPASE-INDEPENDENT APOPTOSIS INITIATED BY VIRAL 

PB1-F2 PROTEIN 

Suzuki, Takashi; Takahashi, Tadanobu; Takaguchi, Masahiro 

Department of Biochemistry, University of Shizuoka, School of Pharmaceutical 

Sciences and Global COE Program, JAPAN 

F38 

IDENTIFICATION OF THE FIRST-KNOWN INHIBITORS OF O-ACETYL 

PEPTIDOGLYCAN ESTERASE: A POTENTIAL NEW ANTIBACTERIAL 

TARGET 

Clarke, Anthony; Pfeffer, John 

University of Guelph, CANADA 

F39 

STRUCTURAL EVIDENCE FOR AN INDUCED FIT OF E-SELECTIN UPON 

SMALL MOLECULE LIGAND BINDING 

Preston, Roland 1 ; Schwizer, Daniel1 ; Wagner, Bea 1 ; Binder, Florian 1 ; Jakob, 

Roman 2 ; Maier, Timm 2 ; Ernst, Beat 1 

1 Institute of Molecular Pharmacy, University of Basel, SWITZERLAND 

2 Biocenter, University of Basel, SWITZERLAND 

2, 3 

33 

MONDAY 23

MONDAY 23 

34 

F40 

OLIGOSACCHARIDE CONFORMATIONAL DYNAMICS ANALYSES BY 

USING PCS IN CONJUNCTION WITH MD SIMULATION 

Zhang, Ying 1,2,3 ; Yamaguchi, Takumi1,2 ; Yamamoto, Sayoko 1,3 ; Kato, Koichi 1,2,3 

1 Okazaki Institute For Integrative Bioscience, National Institutes of Natural 

Sciences, JAPAN 

2 Department of Functional Molecular Science, The Graduate University for 

Advanced Studies (SOKENDAI), Okazaki, JAPAN 

3 Graduate School of Pharmaceutical Sciences, Nagoya City University, 

Nagoya, JAPAN 

F41 

O-GLYCOSYLATION IN SNAILS 

Staudacher, Erika 1 ; Stepan, Herwig1 ; Pabst, Martin 1 ; Altmann, Friedrich 1 ; 

Geyer, Hildegard 2 ; Geyer, Rudolf 2 

1 University of Natural Resources and Life Sciences Vienna, AUSTRIA 

2 University of Giessen, GERMANY 

F42 

A NOVEL GLYCOSYNTHASE DERIVED FROM AN INVERTING FAMILY 

GH19 CHITINASE 

Ohnuma, Takayuki 1 ; Fukuda, Tatsuya1 ; Dozen, Satoshi 1 ; Shinya, Shoko 1 ; 

Numata, Tomoyuki 2 ; Honda, Yuji 3 ; Kitaoka, Motomitsu 4 ; Fukamizo, Tamo 1 

1 Kinki University, JAPAN 

2 National Institute of Advanced Industrial Science and Technology 

3 Ishikawa Prefectural University, JAPAN 

4 National Food Research Institute 

18.30-19.15 Room 3: Hidalgo 

Session 11. Glycosaminoglycans 

FLASH 

F43 

HEPARIN DERIVATIVES FOR THE TREATMENT OF CHRONIC ULCERS 

Franco, Guillermo; Gómez Ochoa, María Teresa; Moraleda Navamuel, José 

Luis 

Laboratorios Farmacéuticos Rovi S.A., SPAIN 

F44 

TOWARD TOTAL SYNTHESIS OF O-ANTIGEN REPEAT UNIT OF E. coli 

O86:B7 BY MODULATING ALPHA-GLYCOSYLATION METHOD 

Hung, Wei-Cheng 

National Chiao-Tung University, TAIWAN 

F45 

NMR AND HPLC/MS CHARACTERIZATION OF GLYCOL-SPLIT HEPARINS 

AND LOW-MOLECULAR WEIGHT HEPARINS 

Naggi, Annamaria 

Istituto Di Ricerche Chimiche E Biochimiche G. Ronzoni, ITALY 

Madrid, Spain

July 22-27, 2012. 

F46 

SYNTHESIS AND STRUCTURAL ANALYSIS BY NMR AND X-RAY OF 

NOVEL IDURONATES ADOPTING 1C4, 4C1 AND 0S2 CONFORMATIONS 

Hansen, Steen 1 ; Miller, Gavin1 ; Barath, Marek 1 ; Avizientye, Egle 2 ; Jayson, 

Gordon 1 ; Gardiner, John 1 

1 School of Chemistry, The University of Manchester, UNITED KINGDOM 

2 School of Cancer and Enabling Sciences, University of Manchester, UNITED 

KINGDOM 

F47 

DESORPTION IONIZATION ELECTROSPRAY MASS SPECTROMETRY: A 

PROMISING TOOL FOR CHARACTERIZATION OF GLYCOSAMINOGLYCANS 

AND THEIR NON-COVALENT COMPLEXES WITH PROTEINS 

Przybylski, Cédric 1 ; Gonnet, Florence1 ; Hersant, Yaël 2 ; Bonnaffé, David 2 ; 

Lortat-Jacob, Hugues 3 ; Daniel, Régis 1 

1 Université D’Evry-Val-D’Essonne, Laboratoire Analyse et Modélisation pour la 

Biologie et l’Environnement, LAMBE, CNRS UMR 8587, FRANCE 

2 Université Paris-Sud, Laboratoire de Chimie Organique Multifonctionnelle, 

ICMO, CNRS UMR 8182, Orsay, FRANCE. 

3 Université Joseph Fourier, Laboratoire d’Enzymologie Moléculaire, LEM, 

CNRS UMR 5075, IBS, Grenoble, FRANCE 

F48 

HIGHLY SPECIFIC LECTIN-GLYCOSPHINGOLIPID INTERACTIONS 

INDUCE THE CELLULAR UPTAKE OF DIVERSE TOXINS AND PATHOGENS 

Römer, Winfried; Eierhoff, Thorsten 

Albert-Ludwigs-University Freiburg 

F49 

A GENERAL STRATEGY FOR THE SOLID PHASE SYNTHESIS OF 

GLYCOSAMINOGLYCANS 

Guedes Carrera, Nerea; Kopitzki, Sebastian; Mitxelena, Olatz; Martin-Lomas, 

Manuel; Reichardt, Niels-Christian 

CICbiomaGUNE, San Sebastián, SPAIN 

F50 

STRUCTURE AND BIOLOGICAL ACTIVITY OF A FUCOSYLATED 

CHONDROITIN SULPHATE ISOLATED FROM THE SEA CUCUMBER, 

Holothuria forskali 

Panagos, Charalampos 1 ; August, David1 ; Thomson, Derek 2 ; Moss, Claire 2 ; 

Bavington, Charlie 2 ; Hughes, Adam 3 ; Kelly, Maeve 3 ; Uhrin, Dusan 1 

1 University of Edinburgh, EaStCHEM School of Chemistry, Edinburgh, UNITED 

KINGDOM 

2 Glycomar Ltd, European Centre for Marine Biotechnology, Dunstaffnage 

Marine Laboratory, Oban, Argyll, UNITED KINGDOM 

3 Scottish Association for Marine Science, Scottish Marine Institute, Oban, 

Argyll, UNITED KINGDOM 

35 

MONDAY 23

MONDAY 23 

36 

F51 

ANTIVIRAL ACTIVITY OF SULFATED GLUCURONIDE DERIVATIVE 

TARGETING DENGUE VIRUS E PROTEIN 

Hidari, Kazuya 1 ; Ikeda, Kiyoshi2 ; Watanabe, Ippei 1 ; Morita, Kouichi 3 ; Suzuki, 

Takashi 1 

1 Department of Biochemistry, School of Pharmaceutical Sciences, University of 

Shizuoka, and Global COE Program for Innovation in Human Health Sciences, 

JAPAN 

2 Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, 

Hiroshima International University, JAPAN 

3 Department of Virology, Institute of Tropical Medicine, Nagasaki University, 

JAPAN 

18.30-19.15 Room 4: Doblón 



F52 

RATIONAL DESING OF MUC-1 BASED VACCINES AGAINST TUMOURS 

Martínez Sáez, Nuria; Somovilla Busto, Víctor Jesús; Madariaga Merino, David; 

Corzana López, Francisco; Busto Sancirián, Jesús Héctor; Avenoza Aznar, 

Alberto; Peregrina García, Jesús Manuel 

Universidad de La Rioja, SPAIN 

F53 

STRUCTURES OF MERKEL CELL POLYOMAVIRUS VP1 COMPLEXES 

DEFINE A SIALIC ACID BINDING SITE REQUIRED FOR INFECTION 

Neu, Ursula 1 ; Hengel, Holger 1 ; Blaum, Baerbel S. 1,2 ; Schowalter, Rachel M. 3 ; 

Macejak, Dennis 4 ; Gilbert, Michel 5 ; Wakarchuk, Warren 5 ; Imamura, Akihiro 6,7 ; 

Ando, Hiromune 6,7 ; Kiso, Makoto 6,7 ; Arnberg, Niklas 8 ; Garcea, Robert 4 ; Peters, 

Thomas 2 ; Buck, Christopher 3 ; Stehle, Thilo 1,9+ 

1 Interfaculty Institute For Biochemistry, University of Tuebingen, GERMANNY 

2 Department of Chemistry, University of Luebeck, GERMANY 

3 Laboratory of Cellular Oncology, National Cancer Institute, Bethesda, USA 

4 Department of Molecular, Cellular and Developmental Biology, and The 

Biofrontiers Intitute, University of Colorado at Boulder, USA 

5 Institute For Biological Science, National Research Council Canada, Ottawa, 

CANADA 

6 Institute For Integrated Cell-Material Sciences, Kyoto University, JAPAN 

7 Department of Applied Bioorganic Chemistry, Gifu University, JAPAN 

8 Division of Virology, Department of Clinical Microbiology, Umea University, 

SWEDEN 

9 Department of Pediatrics, Vanderbilt University School of Medicine, USA 

F54 

PARAMAGNETIC Gd-BASED GOLD GLYCONANOPARTICLES FOR 

LABELLING AND IMAGING CELL RECEPTORS 

Marradi, Marco 1,2 ; Irure, Ainhoa 1 ; Genicio, Nuria 1 ; Arnaiz, Blanca 1 ; Penadés, 

Soledad 1,2 

1 CIC biomaGUNE, San Sebastian, SPAIN 

2 CIBER-BBN, Zaragoza, SPAIN 

Madrid, Spain

July 22-27, 2012. 

F55 

A LECTIN FROM OPPORTUNISTIC PATHOGEN Burkholderia ambifaria 

BINDS TO BOTH PLANT AND HUMAN FUCOSYLATED EPITOPES 

Audfray, Aymeric1 ; Varrot, Annabelle1 ; Ruvoën-Clouet, Nathalie 2 ; Le Pendu, 

Jacques2 ; Imberty, Anne 1 

1 CERMAV-CNRS, Grenoble, FRANCE 

2 IRTUN-INSERM U892, Nantes, FRANCE 

F56 

NEW INSIGHTS INTO Streptococcus pneumoniae LIPOTEICHOIC ACID 

STRUCTURE AND FUNCTION 

Gisch, Nicolas 1 ; Kohler, Thomas2 ; Ulmer, Arthur J. 1 ; Lindner, Buko1 ; 

Hammerschmidt, Sven 2 ; Zähringer, Ulrich 1 

1 Research Center Borstel, GERMANY 

2 Ernst Moritz Arndt University of Greifswald, GERMANY 

F57 

STRUCTURAL INVESTIGATIONS OF AN ARABINOGALACTAN PROTEIN 

FROM Jatropha curcas L. SEEDS 

Sehlbach, Maria; Hensel, Andreas 

Institute of Pharmaceutical Biology and Phytochemistry, Münster, GERMANY 

F58 

TRANSCRIPTION FACTOR MIMICS: THE O- β-D-GlcNAc-Ser/Thr AND 

Phos-Ser/Thr SWITCH 

Del Villar-Guerra, Rafael 1 ; Marcelo, Filipa2 ; García-Puentes, Diego 1 ; Cañada, 

Javier 2 ; Jiménez-Barbero, Jesús 2 ; Vicent, Cristina 1 

1 Instituto de Química Orgánica General, CSIC, Madrid, SPAIN 


F59 

CHARACTERIZATION OF N-GLYCAN MOIETIES WITHIN THE 66-KDA 

CELL-WALL GLYCOPROTEIN FROM THE RED MICROALGA 

Levy-Ontman, Oshrat 1 ; (Malis) Arad, Shoshana2 1 SCE -Sami Shamoon College of Engineering, ISRAEL 

2 Ben-Gurion University of the Negev, Beer-Sheva, ISRAEL 

F60 

EXPLORATION OF BIOLOGICALLY RELEVANT BINDING MOTIFS USING 

CARBOHYDRATE DNA CONJUGATES 

Morales, Juan Carlos 1 ; Lucas, Ricardo1 ; Vengut-Climent, Empar 1 ; Gómez- 

Pinto, Irene2 ; Aviñó, Anna 3 ; Eritja, Ramón 3 ; González, Carlos2 1 Instituto de Investigaciones Químicas, CicCartuja, CSIC-Universidad de 

Sevilla, SPAIN 

2 Instituto de Química-Física Rocasolano, CSIC, Madrid, SPAIN 

3 Instituto de Investigación Biomédica de Barcelona, IQAC, CSIC, CIBER- 

BBN Networking Centre on Bioengineering, Biomaterials and Nanomedicine, 


37 

MONDAY 23

TUESDAY 24 

Tuesday 24 


38 

Plenary 4 

Galactofuranose Incorporation from Mycobacteria to Worms 

L.L. Kiessling (Wisconsin), Departments of Chemistry and Biochemistry, 

University of Wisconsin-Madison 

Chair: S. Penades (San Sebastián) 


Plenary 5 

Sweet-talk between pathogens and hosts-from structural glycobiology to 

antiadhesive strategies 

A. Imberty (Grenoble), Cermav-Cnrs 

Chair: M. Aebi (Zürich) 

10:00-10:45 Coffee - Poster 



INV. 13. The Gold(I)-Catalyzed Glycosylation with Glycosyl 

ortho-Alkynylbenzoates as Donors 

B. Yu (Shangai), State Key Laboratory of Bioorganic and Natural Products 

Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of 

Sciences 

Chairs: S. Castillón (Tarragona), A. Fairbanks (Christchurch) 

11:00-11:30 Room 4: Doblón 


INV. 14. Towards lipopol y Saccharide-based conjugate vaccines based 

on sythetic oligosaccharides 

S.Oscarson (Ireland) 

Chairs: Niels Reichardt, Injae Shin (Seoul) 


Session 15. Glycobiology, Vaccaines & Glycoinformatics 

INV. 15. Diversity of carbohydrate binding sites in β-prism fold lectins 

A. Surolia (New Delhi), Indian Institute Of Science 

Chairs: M. Palcic (Copenhagen), C. Nativi (Florence) 

Madrid, Spain

11:00-11:30 Room 3: Hidalgo 

July 22-27, 2012. 

Session 16. Glicobiology & Chemical Glycobiology 

INV. 16. Functionalized Nanoparticles for Protein Enrichment and Cell 

Targeting 

C. C. Lin (Hsinchu), National Tsing Hua University 

Chairs: Z. Witczak (Wilkes-Barre), Y. Bleriot (Poitiers) 



ORAL 

O53 

PHOSPHATIDYL INOSITOL MANNOSIDES (PIM) MIMICS: SYNTHESIS, 

BIOLOGICAL ACTIVITIES, AND IN-CELL TRACING 

Martin, Olivier 1 ; Front, Sophie1 ; Rose, Stéphanie 2 ; Bourigault, Marie-Laure 2 ; 

Quesniaux, Valérie 2 

1 University of Orleans & CNRS (ICOA), FRANCE 

2 University of Orleans & CNRS (INEM), FRANCE 

O54 

SYNTHESIS OF CARBOBICYCLIC SUGAR MIMICS 

Jarosz, Slawomir 

Institute of Organic Chemistry, Polish Academy of Sciences, POLAND 

O55 

THE SYNTHESIS OF TETRAFLUORINATED GALACTOSE DERIVATIVES 

Golten, Samuel; Linclau, Bruno 

University of Southampton, UNITED KINGDOM 

O56 

SKELETAL REARRANGEMENT OF SEVEN-MEMBERED IMINOSUGARS 

Blériot, Yves; Désiré, Jérôme; Mondon, Martine; Fontelle, Nathalie; Guillard, 

Jérôme; Lecornué, Frédéric 

Poitiers University, FRANCE 

O57 

ANOMERIC SPIROCYCLES BY SOLVENT INCORPORATION: REACTIONS 

OF O-PERACYLATED (GLYCULOPYRANOSE)ONAMIDE DERIVATIVES 

WITH KETONES 

Páhi, András 1 ; Czifrák, Katalin1 ; Kövér E., Katalin 2 ; Somsák, László 1 

1 Department of Organic Chemistry, University of Debrecen, HUNGARY 

2 Department of Inorganic and Analytical Chemistry, University of Debrecen, 

HUNGARY 

O58 

NUCLEOPHILE ORIENTATION IN GLYCOSYLATION REACTIONS 

Whitfi eld, Dennis 

National Research Council, CANADA 

39 

TUESDAY 24

TUESDAY 24 

11.30-13.00 Room 4: Doblón 


ORAL 

O59 

‘GLYCO’-FOLDAMERS AS INHIBITORS OF BACTERIAL ADHESION: 

SYNTHESIS & BIOLOGICAL ACTIVITY 

Siriwardena, Aloysius 1 ; Chakraborty, Tushar2 ; Ampipathi, Ravishankar 2 ; 

Martín, Fernando 3 ; Beloin, Christophe 3 ; Jiménez-Barbero, Jésus 4 ; Friere, 

Ana 4 ; Woods, Robert 5 ; Ito, Keigo 5 ; Roy, Saumya 1 

1 CNRS, Amiens, FRANCE 

2 IICT, Lucknow, INDIA 

3 Institute Pasteur de Paris, FRANCE 

4 CIB, Madrid, SPAIN 

5 Complex Carbohydrate Research Center, Athens, GA, USA 

O60 

DESIGN OF ENTRY INHIBITORS AGAINST HUMAN NOROVIRUSES 

Fiege, Brigitte 1 ; Guiard, Julie2 ; Rademacher, Christoph 1,3 ; Kitov, Pavel I. 2 ; 

Cartmell, Jonathan 2 ; Dalton, Kevin P. 4 ; Parra, Francisco 4 ; Bundle, David R. 2 ; 

Peters, Thomas 1 

1 Institute of Chemistry, University of Luebeck, Luebeck, GERMANY 

2 Department of Chemistry, University of Alberta, Edmonton, CANADA 

3 Department of Biomolecular Systems, Max Planck Institute of Colloids and 

Interfaces, Berlin, GERMANY 

4 Departamento de Bioquímica y Biología Molecular, Universidad de Oviedo, 

Oviedo, SPAIN 

O61 

INTEGRATED ‘OMICS’, STRUCTURAL BIOLOGY AND GREEN CHEMISTRY 

INVOLVING GLYCOSIDE HYDROLASE FAMILY 36 FOR DISCOVERY OF 

OLIGOSACCHARIDE PREBIOTICS 

Svensson, Birte 1 ; Fredslund, Folmer1 ; Majumder, Avishek 1 ; Andersen, 

Joakim M. 1 ; Coutinho, Pedro M. 2 ; Nakai, Hiroyuki 3 ; Jacobsen, Susanne 1 ; 

Lo Leggio, Leila 4 ; Abou Hachem, Maher 1 

1 Enzyme and Protein Chemistry, Department of Systems Biology, Technical 

University of Denmark, DENMARK 

2 Architecture et Fonction des Macromolecules Biologiques, CNRS & Université 

d’Aix Marseille, FRANCE 

3 Graduate School of Science & Technology, Niigata University, Niigata, JAPAN 

4 Biophysical Chemistry Group, Department of Chemistry, University of 

Copenhagen, DENMARK 

O62 

GLYCOLANDSCAPING LIVING CELLS 

Bovin, Nicolai 1 ; Henry, Stephen2 ; Korchagina, Elena 1 ; Tuzikov, Alexander 1 

1 Shemyakin&Ovchinnikov Institute of Bioorganic Chemistry, Moscow, RUSSIA 

2 Biotechnology Research Institute, AUT University, Auckland, NEW ZEALAND 

40 

Madrid, Spain

July 22-27, 2012. 

O63 

8-β-D-GLUCOSYLGENISTEIN: SYNTHESIS AND PPLICATION IN 

DIABETES AND ALZHEIMER’S DISEASE 

Jesus, Ana Rita 1 ; Ribeiro, Rogério2 ; Macedo, Paula 2 ; Airoldi, Cristina 3 ; Nicotra, 

Francesco 3 ; Jiménez-Barbero, Jesús 4 ; Rauter, Amélia1 1 Faculdade de Ciências da Universidade de Lisboa, PORTUGAL 

2 Faculdade de Ciências Médicas da Universida de Nova de Lisboa, PORTUGAL 

3 Università degli Studi di Milano-Bicocca, ITALY 


O64 

METABOLIC LABELING OF THE LIPOPOLYSACCHARIDES OF LIVING 

BACTERIA 

Vauzeilles, Boris 1 ; Dumont, Audrey2 ; Malleron, Annie 1 ; Awwad, Monzer 1 ; 

Dukan, Sam 2 

1 ICMMO-CNRS and Univ. Paris-Sud, Orsay, FRANCE 

2 LCB-IMM-CNRS and Aix-Marseille Université, FRANCE 


Session 15. Glycobiology, Vaccines & Glycoinformatics 

ORAL 

O65 

AN OPTIMAL CONJUGATE VACCINE FOR Candida albicans BY REVERSE 

ENGINEERING A MONOCLONAL ANTIBODY 

Bundle, David 1 ; Johnson, Margaret 1 ; Lipinski, Tomas 2 ; Cartmell, Jonathan 1 ; 

Dziadek, Sebastian 3 ; Xin, Hong 4 ; Cutler, Jim 4 

1 AlbertaGlycomics Centre, Department of Chemistry, University of Alberta, 

CANADA 

2 Institute of Immunology and Experimental Therapy, Polish Academy of 

Sciences, POLAND 

3 Roche Diagnostics GmbH, GERMANY 

4 Department of Pediatrics, Louisiana State University Health Sciences Center 

and Research Institute for Children, Children’s Hospital, New Orleans, USA 

O66 

SYNTHETIC TEICHOIC ACID FRAGMENTS FOR Enterococcus faecalis 

VACCINE APPLICATIONS 

Van der Marel, Gijs1 ; Hogendorf, Wouter1 ; Meeuwenoord, Nico1 ; Overkleeft, 

Herman1 ; Kropec, Andrea 2 ; Huebner, Johannes 2 ; Codee, Jeroen1 1 Leiden University, NETHERLANDS 

2 University Medical Center Freiburg, GERMANY 

O67 

BIOSYNTHESIS OF LEISHMANIA LIPOPHOSPHOGLYCAN: ELONGATING 

AND BRANCHING GALACTOSYLTRANSFERASES ARE DEPICTED USING 

SYNTHETIC ACCEPTOR SUBSTRATES 

Nikolaev, Andrei; Sizova, Olga; Ferguson, Michael 

University of Dundee, UNITED KINGDOM 

41 

TUESDAY 24

TUESDAY 24 

42 

O69 

DEVELOPMENT AND ANALYSIS OF A GLYCOCONJUGATE VACCINE 

AGAINST SHIGELLOSIS 

Ravenscroft, N. 1 ; Fernandez, F. 2 ; Braun, M. 2 ; Wetter, M. 2 ; Haeuptle, M.A. 2 ; 

Steffen, M. 2 ; Carranza, P. 2 ; Gambillara, V. 2 ; Kowarik, M. 2 ; Wacker, M. 2 

1 Department of Chemistry, University of Cape Town, SOUTH AFRICA 

2 GlycoVaxyn AG, Schlieren, SWITZERLAND. 

O70 

TARGETING THE GLYCANS OF THE GLYCOPROTEIN GP120 AS A 

PROMISING STRATEGY FOR ANTI-HIV THERAPY 

San-Felix, Ana 1 ; Carrero, Paula1 ; Lozano, Virginia 1 ; Ardá, Ana 2 ; Álvarez, 

Mónica 3 ; Solís, Dolores 3 ; Camarasa, María José 1 ; Jiménez-Barbero, Jesús 2 ; 

Balzarini, Jan 4 ; Pérez-Pérez, María Jesús 1 

1 Instituto de Química Médica, CSIC, Madrid, SPAIN 



4 Rega Institute for Medical Research, Leuven, BELGIUM 

11.30-13.00 Room 3: Hidalgo 

Session 16. Glycobiology & Chemical Glycobiology 

ORAL 

O71 

SUGARS AND PROTEINS 

Davis, Benjamin 

University of Oxford, UNITED KINGDOM 

O72 

POLYESTER GLYCODENDRIMERS AND DENDRONIZED POLYMERS 

AS POTENTIAL ANTIADHESION DRUGS AGAINST URINARY TRACT 

INFECTIONS 

Grindley, T. Bruce; Twibanire, Jean-D’Amour 

Department of Chemistry, Dalhousie University, CANADA 

O73 

CHEMOENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES AND GLICO- 

CONJUGATES WITH ANTIGENIC PROPERTIES 

Terreni, Marco 1 ; Bavaro, Teodora1 ; Temporini, Caterina 1 ; Serra, Immacolata 1 ; 

Speranza, Giovanna 2 ; Fasanella, Francesco 2 

1 University of Pavia, ITALY 

2 University of Milan, ITALY 

O74 

DEVELOPMENT OF FUCOSYLTRANSFERASE AND FUCOSIDASE 

INHIBITORS BY STRUCTURE- AND SCREENING-BASED APPROACHES 

Lin, Chun-Hung Hans; Tu, Zhijay 

Institute of Biological Chemistry, Academia Sinica, TAIWAN 

Madrid, Spain

July 22-27, 2012. 

O75 

O-ANTIGEN PHOSPHORYLATION IN Shigella fl exneri: A CLUE TO THE 

ENIGMA OF THE MONOCLONAL ANTIBODY MASF IV-I SPECIFITY 

Knirel, Yuriy 1 ; Xu, J2 ; Senchenkova, S.N. 1 ; Lan, R. 3 ; Kondakova, A. 1 ; Sun, Q. 

2 1 1 

; Perepelov, A.V. ; Shashkov, A.S. 

1 N.D. Zelinsky Institute of Organic Chemistry, RUSSIA 

2 National Institute for Communicable Disease Control and Prevention, CHINA 

3 School of Biotechnology and Biomolecular Sciences, University of New South 

Wales, AUSTRALIA 

O76 

THIO-CLICK CHEMISTRY APPROACH TO GLYCOMIMETICS. SYNTHESIS 

AND DESIGNOF NEW THIO SUGARS AS POTENTIAL INHIBITORS OF 

GALECTIN-3 

Witczak, Zbigniew J.; Jankowski, Arthur; Silvi, Silvia 

Department of Pharmaceutical Sciences, Nesbitt School of Pharmacy, USA 


Session 13 Synthesis: Methods and Applications 

FLASH 

F61 

CARBOHYDRATE-BASED 1,3-OXAZOLINE-2-THIONES: FROM 

SYNTHESIS TO BIOLOGICAL APPLICATIONS 

Castilla López, Javier 1 ; Cruz, Deisy1 ; Rísquez Cuadro, Rocío 2 ; Ortiz Mellet, 

Carmen 2 ; García Fernández, José Manuel 3 ; Díaz, Yolanda 1 ; Castillón, Sergio1 1 Universitat Rovira I Virgili, SPAIN 

2 Universidad de Sevilla, SPAIN 

3 Instituto de Investigaciones Químicas, CSIC-Universidad de Sevilla, SPAIN 

F62 

SYNTHESIS OF Staphylococcus aureus TYPE 5 CAPSULAR 

POLYSACCHARIDE REPEATING UNIT 

Adamo, Roberto 1 ; Danieli, Elisa1 ; Proietti, Daniela 1 ; Brogioni, Giulia 1 ; Tontini, 

Marta1 ; Romano, Maria R. 1 ; Cappelletti, Emilia 1 ; Lay, Luigi 2 ; Costantino, Paolo 

1 1 

; Berti, Francesco 

1 Novartis Vaccine & Diagnostics, Siena, ITALY 

2 University of Milan, ITALY 

43 

TUESDAY 24

TUESDAY 24 

44 

F63 

PYRROLIDINES: DIVERGENT ACCESS TO ALL STEREOISOMERS FROM 

GLUCURONOLACTONE 

Ayers, Benjamin1 ; Jenkinson, Sarah1 ; Ngo, Nigel 1 ; Best, Daniel 1 ; Martinez, 

Fernando1 ; Kato, Atsushi 2 ; Fleet, George 1 

1 Department of Chemistry, University of Oxford, UNITED KINGDOM 

2 Department of Pharmacy, University of Toyama, JAPAN 

F64 

SEQUENCIAL ENZYMATIC SYNTHESIS OF SUGAR NUCLEOTIDES AND 

Poly-LacNAc 

Chien, Wei-Ting; Lin, Chun-Cheng 

National Tsing Hua Univerity, TAIWAN 

F65 

AUTOMATED SOLID PHASE SYNTHESIS OF AN ALPHA-(1-6)-30-MER 

OLIGOMANNAN 

Calin, Oliviana; Eller, Steffen; Seeberger, Peter H. 

Max Planck Institute, GERMANY 

F66 

FUNCTIONALIZATION OF EXO-GLYCALS: RECENT PROGRESSES 

Chapleur, Yves; Pellegrini-Moïse, Nadia; Richard, Mylène; Felten, Anne-Sophie 

Universite de Lorraine, FRANCE 

13.00-13.30 Room 4: Doblón 


FLASH 

F67 

THE BIOLOGICAL FUNCTIONS AND BLOOD CONCENTRATION OF CL- 

K1. 

Wakamiya, Nobutaka; Ohtani, Katsuki; Yoshizaki, Takayuki; Mori, Kenichiro; 

Matsuda, Yasuyuki ; Yoshida, Itsuro; Suzuki, Yasuyuki 

Asahikawa Medical University, JAPAN 

F68 

C-MANNOSYLATION OF ALL CYS DOMAINS OF MUC5B IS REQUIRED 

FOR THE PROPER FOLDING AND MATURATION OF MUCIN 

Desseyn, Jean-Luc 1, 2 ; Robbe-Masselot, Catherine 2,3 ; Cieniewski-Bernard, 

Caroline 2,4 ; Gottrand, Frédéric 1,2,5 ; Gouyer, Valérie 1,2,5 

1 Inserm U995-Lille, FRANCE 

2 Univ Lille Nord de France, Lille, FRANCE 

3 CNRS, UMR 8576, Villeneuve d’Ascq, FRANCE 

4 EA4488, Villeneuve d’Ascq, FRANCE 

5 CHRU of Lille, Lille, FRANCE 

Madrid, Spain

July 22-27, 2012. 

F69 

SITE-SPECIFIC N-GLYCOSYLATION OF THE ENVELOPE PROTEIN OF 

SANOFI PASTEUR PROTOTYPE VACCINE AGAINST DENGUE 

Talaga, Philippe; Dubayle, Jean; Vialle, Sandrine; Schneider, Diane; Mantel, 

Nathalie; Guy, Bruno 

Sanofi Pasteur, Lyon, FRANCE 

F70 

FACILE AND STEREOSELECTIVE SYNTHESIS OF ALTERNATIVE α (2→8)/ 

α (2→9) OLIGOSIALIC ACIDS UP TO DODECAMERS 

Pal, Bikash; Han, Jeng-Liang; Wong, Chi-Huey; Wu, Chung-Yi 

Genomics Research Center, Academia Sinica, TAIWAN 

F71 

SYNTHESIS AND BIOLOGICAL INVESTIGATION OF PHOTOLABILE 

CARBOHYDRATE LIGANDS FOR THE BACTERIAL LECTIN FIMH 

Beiroth, Femke; Lindhorst, Thisbe K. 

Christiana Albertina University of Kiel, GERMANY 

F72 

DETAIL STRUCTURAL INFORMATION OF SPECIFICITY DETERMINING 

INTERACTIONS IN ENGINEERED CARBOHYDRATE BINDING MODULES 

von Schantz, Laura 1 ; Håkansson, Maria2 ; Logan, Derek 2 ; Walse, Björn 2 ; 

Österlin, Jacob 1 ; Nordberg-Karlsson, Eva 3 ; Ohlin, Mats 1 

1 Dept. of Immuntechnology, Lund University, SWEDEN 

2 SARomics Biostructures AB, Lund, SWEDEN 

3 Dept. of biotechnology, Lund University, SWEDEN 


Session 15. Glycobiology, Vaccines & Glycoinformatics 

FLASH 

F73 

GLYCOLIPIDOMICS BY TLC-BLOT MALDI-TOF MS -GANGLIOSIDES IN 

ALZHEIMER’S DISEASE- 

Taki, Takao 1 ; Hirano, Wakao1 ; Sakurai, Kazushi 1 ; Hayasaka, Takahiro 2 ; Setou, 

Mitsutoshi 2 ; Goto-Inoue, Naoko 3 

1 Tokushima Institute, Otsuka Pharmaceutical Co. Ltd., JAPAN 

2 Department of Cell Biology and Anatomy, Hamamatsu University School of 

Medicine, JAPAN 

3 Department of Health Promotion Sciences,Tokyo Metropolitan University, 

JAPAN 

F74 

DETECTION OF GLYCOSYLTRANSFERASE ACTIVITY ON GLYCAN 

MICROARRAYS BY TRITIUM IMAGING. 

Serna, Sonia 1 ; Weissenborn, Martin J. 2 ; Flitsch, Sabine L. 2 ; Martin-Lomas, 

Manuel 1,3 ; Reichardt, Niels Christian 1,3 

1 CIC biomaGUNE, San Sabastian, SPAIN 

2 Manchester Interdisciplinary Biocentre (MIB), UNITED KINGDOM 

3 CIBER BBN, Zaragoza, SPAIN 

45 

TUESDAY 24

TUESDAY 24 

46 

F75 

OPTICAL ACTIVITY OF GOLD (I) GLYCOCONJUGATE-THIOLATE 

COMPLEXES 

Pourceau, Gwladys 1 ; Di Gianvincenzo, Paolo1 ; Penadés, Soledad 1,2 

1 Lab. of GlycoNanotechnology, CIC BiomaGUNE, San Sebastian, SPAIN 

2 Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y 

Nanomedicina, CIBER-BBN, Zaragoza, SPAIN 

F76 

JCGGDB AND GLYCOPROTDB 

Shikanai, T.; Kaji, H.; Suzuki, Y.; Fujita, N.; Maeda, M.; Wen, H.; Ishizaki, M.; 

Sawaki, H.; Narimatsu, H. 

Research Center For Medical Glycoscience (RCMG), National Institute of 

Advanced Industrial Science and Technology (AIST), Tsukuba, JAPAN 

F77 

GALECTINS AS PATTERN RECOGNITION RECEPTORS 

Vasta, Gerardo 

Department of Microbiology and Immunology University of Maryland School of 

Medicine, USA 

F78 

AMINO ACID PRESENCE IN THE SPATIAL VICINITY OF N-GLYCOSYLATION 

SITES 

Rojas Macias, Miguel Angel; Lütteke, Thomas 

Institute of Veterinary Physiology and Biochemistry, Justus Liebig University 

Gießen, GERMANY 

13.00-13.30 Room 3: Hidalgo 

Session 16. Glycobiology & Chemical Glycobiology 

FLASH 

F79 

DISSECTING THE INVERTASE MECHAMISM: THE KEY ROLE OF ITS 

NON-CATALYTIC DOMAIN 

Sáinz Polo, María Ángela 1 ; Ramírez, Mercedes1 ; González, Beatriz 1 ; Álvaro, 

Miguel 2 ; Fernández Lobato, María 2 ; Lafraya, Álvaro 3 ; Marín, Julia 3 ; Polaina, 

Julio 3 ; Sanz Aparicio, Julia 1 

1 Department of Crystallography and Structural Biology, Instituto de Química 

Física “Rocasolano”, CSIC, Madrid, SPAIN 

2 Department of Molecular Biology, Centro de Biología Molecular “Severo 

Ochoa” CSIC-UAM, Madrid, SPAIN 

3 Instituto de Agroquímica y Tecnología de Alimentos, CSIC, Valencia, SPAIN 

Madrid, Spain

July 22-27, 2012. 

F80 

SAR STUDY OF GLYCOGEN PHOSPHORYLASE INHIBITORS: 

HETEROCYCLES AS BIOISOSTERIC AMIDE REPLACEMENTS IN 

N-ACYL-β-DGLUCOPYRANOSYLAMINES AND 

N-ACYL-N’-β-D-GLUCOPYRANOSYL UREAS 

Vágvölgyiné Dr. Tóth, Marietta 1 ; Varga, Gergely Tibor1 ; Polyák, Mária 1 ; 

Szilágyi, Bence 1 ; Kun, Sándor1 ; Takács, István 1 ; Juhász, László1 ; Docsa, Tibor 

2 2 1 

; Gergely, Pál ; Somsák, László 

1 Department of Organic Chemistry, University of Debrecen, HUNGARY 

2 Department of Medical Chemistry, Medical and Health Science Centre, 

University of Debrecen, HUNGARY 

F81 

CHECK THAT FLUORIDE! NOT JUST ANOTHER UNIVERSAL 

GLYCOSYNTHASE HTS METHOD 

Andrés Martínez, E.; Planas, A. 

Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull, 


F82 

STRUCTURAL FEATURES OF HYPERBRANCHED α-GLUCANS OBTAINED 

IN VITRO USING A NEW ENZYMATIC COCKTAIL 

Rolland-Sabate, Agnes1 ; Grimaud, Florent2 ; Roussel, Xavier3 ; Lancelon-Pin, 

Christine4 ; Laguerre, Sandrine 2 ; Viksø-Nielsen, Anders 5 ; Guilois, Sophie 1 ; 

Putaux, Jean-Luc 4 ; D’Hulst, Christophe 3 ; Veronese, Gabrielle 2 

1 UR1268 Biopolymères Interactions Assemblages, INRA, Nantes, FRANCE 

2 Université de Toulouse, INSA-UPS-INP, LISBP, Toulouse, France; UMR 5504, 

UMR 792 Ingénierie des Systèmes Biologiques et des Procédés, CNRS, INRA, 

Toulouse, FRANCE 

3 UGSF, UMR 8576, Université Sciences et Technologies de Lille, Villeneuve 

d’Ascq, FRANCE 

4 CERMAV-CNRS, Grenoble, France-affi liated with Université Joseph Fourier 

and member of the Institut de Chimie Moléculaire de Grenoble, FRANCE 

5 Novozymes A/S, Bagsvaerd, DENMARK 

F83 

MANNOBIOSIDE FUNCTIONAL MIMICS IN MONO AND SPATIALLY 

CONTROLLED MULTIVALENT PRESENTATIONS 

Varga, Norbert 1 ; Sutkeviciute, Ieva2 ; Vettoretti, Gerolamo 1 ; Fieschi, Franck 2 ; 

Bernardi, Anna 1 

1 Universita’ degli Studi di Milano, Dipartimento di Chimica, Milano, ITALY 

2 Institut de Biologie Structurale, CNRS. Grenoble, FRANCE 

F84 

TANDEM MASS SPECTROMETRY IN THE ANALYSIS OF LINEAR MIXED- 

LINKAGE GLUCOOLIGOSACCHARIDES 

Maina, Ndegwa Henry; Juvonen, Minna; Jokela, Jouni; Tenkanen, Maija 

University of Helsinki, Department of Food and Environmental Chemistry, 

FINLAND 

47 

TUESDAY 24

TUESDAY 24 

13.30-15:00 LUNCH 


48 

Plenary 6 

Investigating carbohydrate-protein interactions using mass spectrometry 

J. Klassen (Alberta) University Of Alberta 

Chair: D. Bundle (Edmonton) 


Session 17. 

INV. 17 . Stereoselective Reactions of Oxocarbenium Ions: 

Conformational Analysis, Stereoelectronic Effects, and Reactivity 

K. A. Woerpel (New York), New York University 

Chair: S. Vincent (Namur) 


Session 18. 

INV. 18. Microbial glycoconjugates as elicitors and suppressors of 

Eukaryotic innate immunity 

A.Molinaro (Napoli), Universita’ Di Napoli Federico II 

Chair: F. Nicotra (Milano) 

15:50-16:20 Room 3: Hidalgo 

Session 19. 

INV. 19. NMR studies on carbohydrate structure and their interactions 

with proteins, a dynamic perspective 

P. M. Nieto (Sevilla), Glycosystems Laboratory, Instituto de Investigaciones 

Químicas – CSIC – US 

Chair: M. Hricovini (Bratislava) 

15:50-16:20 Room 4: Doblón 

Session 20. 

INV. 20 From supramolecular structure and dynamics to biological 

functions of carbohydrate-rich cellular coats-lessons learned from 

biomimetic model systems 

R. Richter (San Sebastián), CIC BiomaGUNE 

Chairs: J. Cañada (Madrid) 

16.20-17:00 Coffee - Poster 

Madrid, Spain


July 22-27, 2012. 


INV. 21 Recent developments in sugar mimickry: new fl uorocarbasugars 

and iminosugars 

M. Sollogoub (Paris) UPMC Sorbonne Université 

Chairs: J. M. García Fernández (Sevilla), S. Oscarson (Dublin) 



INV. 22 Synthetic carbohydrates and vaccines: the challenge of defeating 

bacillary dysentery 

L. A. Mulard (Paris) Institut Pasteur 

Chairs: J. Rojo (Sevilla), O. Varela (Buenos Aires) 

17:00-17:30 Room 3: Hidalgo 


INV. 23 Synthetic Lectins: Biomimetic Receptors for Carbohydrates in 

Water 

A.P. Davis (Bristol) University Of Bristol 

Chairs: P. Nieto (Sevilla), Cristina Vicent (Madrid) 

17:00-17:30 Room 4: Doblón 

Session 24.Glycomaterials: Synthesis and Applications 

INV. 24 Synthesis and Applications of Glyconanomaterials 

O. Ramstrom (Stockholm) Royal Institute Of Technology 

Chairs: G. Widmalm (Stockholm), Ramón Estévez (Santiago de Compostela) 



ORAL 

O77 

FROM CHEMICAL GLYCOSYLATION TO EXPEDITIOUS 

OLIGOSACCHARIDE SYNTHESIS 

Demchenko, Alexei; Pornsuriyasak, Papapida; Yasomanee, Jagodige; 

Nigudkar, Swati 

University of Missouri, St. Louis, USA 

O78 

SUBSTITUENT EFFECTS IN GLYCOSYLATIONS: A COMPARISON OF 

METHYL AND BENZYL ETHERS 

Fügedi, Péter 

Institute of Organic Chemistry, Research Centre For Natural Sciences, 

Hungarian Academy of Sciences, HUNGARY 

49 

TUESDAY 24

TUESDAY 24 

50 

O79 

MICROFLUIDIC GLYCOSYLATION FOR EFFICIENT SYNTHESIS OF 

BIOFUNCTIONAL GLYCANS 

Fukase, Koichi 1 ; Tanaka, Katsunori1,2 ; Fujimoto, Yukari 1 ; Uchinashi, Yosuke 1 ; 

Shimoyama, Atsushi 1,3 

1 Department of Chemistry, Graduate School of Science, Osaka University, 

JAPAN 

2 RIKEN, Advanced Science Institute, JAPAN 

3 Department of Life Science, Graduate School of Bioscience and Biotechnology, 

Tokyo Institute of Technology, JAPAN 

O80 

SYNTHETIC LIPID A MIMETICS AS LIGANDS FOR MODULATION OF 

INNATE AND ADAPTIVE IMMUNITY 

Zamyatina, Alla; Kosma, Paul; Adanitsch, Florian; Artner, Daniel; Baum, David; 

Hollaus, Ralph; Hofbauer, Karin 

University of Natural Resorces and Life Sciences, Department of Chemistry, 

AUSTRIA 

O81 

SYNTHESIS OF S- AND C-GALACTOFURANOSIDES VIA 

GALACTOFURANOSYL IODIDES 

Marino, Carla; Baldoni, Luciana 

CIHIDECAR-UBA-CONICET, Departamento de Química Orgánica, Facultad 

de Ciencias Exactas y Naturales, Universidad de Buenos Aires, ARGENTINA 



ORAL 

O82 

QUANTITATIVE ANALYSIS OF THIOSUGAR SULFONIUMS, POTENT 

α -GLUCOSIDASE INHIBITORS FROM SALACIA SPECIES, USING LC-MS 

Morikawa, Toshio 1 ; Miyake, Sohachiro1 ; Akaki, Junji 1 ; Ninomiya, Kiyofumi 1 ; 

Yoshikawa, Masayuki 1 ; Muraoka, Osamu 1,2 

1 Pharmaceutical Research and Technology Institute, Kinki University, JAPAN 

2 School of Pharmacy, Kinki University, JAPAN 

O83 

HIGH-YIELD ENZYMATIC SYNTHESIS OF Gal β -(1→3) GalNAc and 

Gal β -(1→3) GlcNAc USING RECOMBINANT β-GALACTOSIDASE FROM 

Bacillus Circulans 

Navarrete, S. 1 ; Ruiz, L. 1 ; Bayón, C. 1 ; Sandoval, M. 1 ; Berenguer, J. 2 ; 

Hernáiz, M.J. 1 

1 Organic and Pharmaceutical Chemistry Department, Faculty of Pharmacy. 

Universidad Complutense, Madrid, SPAIN 

2 Center of Molecular Biology Severo Ochoa, CSIC-Autonoma University, 

Madrid, SPAIN 

Madrid, Spain

July 22-27, 2012. 

Young Investigator Session 

O84 

PRINCIPLES OF MUCIN ARCHITECTURE: TOWARDS THE DESIGN OF 

NOVEL GLYCOPEPTIDE-BASED CANCER VACCINES 

Corzana, Francisco 1 ; Busto, Jesús H. 1 ; Madariaga, David 1 ; Martínez-Sáez, 

Nuria 1 ; Somovilla, Víctor J. 1 ; Avenoza, Alberto 1 ; Peregrina, Jesús M. 1 ; 

Asensio, Juan L. 2 ; Jiménez-Barbero, Jesús 3 

1 Universidad de La Rioja, SPAIN 

2 Instituto de Química Orgánica General, CSIC, Madrid, SPAIN 


O85 

NEW INSIGHTS INTO THE BINDING MECHANISM(S) OF THE GLYCO- 

CLUSTER EFFECT: A QUANTITATIVE KINETIC STUDY 

Muñoz, Eva María; Correa, Juan; Fernandez-Megia, Eduardo; Riguera, Ricardo 

University of Santiago de Compostela, SPAIN 

O86 

ANOMERIC SELECTIVE PHARMACOLOGICAL CHAPERONES FOR LSDs 

BASED ON NON-GLYCONIC INTERACTIONS 

García Moreno, María Isabel 

University of Seville, SPAIN 

17.30-18.45 Room 3: Hidalgo 


ORAL 

O87 

CROSSTALK BETWEEN O-GlcNAcylation AND PHOSPHORYLATION IN 

SIGNALING. 

Hart, Gerald 

Johns Hopkins University School of Medicine, USA 

O88 

HYDROGEN BONDS AND CH-Ð INTERACTIONS IN DNA MINOR GROOVE 

CARBOHYDRATE-LIGANDS 

Blazquez-Sanchez, Maria Teresa 1 ; Marcelo, Filipa2 ; Poveda, Ana 3 ; Jiménez- 

Barbero, Jesús 2 ; Cañada, Javier 2 ; Vicent, Cristina 1 

1 Instituto de Química Orgánica General CSIC, Madrid, SPAIN 

2 Centro de Investigaciones Biológicas CSIC, Madrid, SPAIN 

3 Universidad Autónoma de Madrid, SPAIN 

O89 

CARBOHYDRATE-CARBOHYDRATE INTERACTION INVOLVED IN CELL 

RECOGNITION AND ADHESION 

Zhang, Yongmin 

Université Pierre et Marie Curie, FRANCE 

51 

TUESDAY 24

TUESDAY 24 

52 

O90 

RECOGNITION OF SUGAR AT MEMBRANE-WATER INTERFACE 

Gnanakaran, S.; Tian, Jianhui; Parthasarathi, Ramakrishnan; Swanson, Basil; 

Goldstein, Byron 

Los Alamos National Labs, USA 

O91 

HELICAL CAPSULES: SUITABLE CONTAINERS FOR CARBOHYDRATES? 

Ferrand, Yann 

IECB-Université Bordeaux, FRANCE 

17.30-18.45 Room 4: Doblón 

Session 24. Glycomaterials: Synthesis and Applications 

ORAL 

O92 

CARBOHYDRATE GRAFTING ON POLYPROPYLENE SURFACES BY 

HUISGEN-TYPE CYCLOADDITION 

Cipolla, Laura 1 ; Russo, Laura 1 ; Zanini, Stefano 2 ; Riccardi, Claudia 2 ; Nicotra, 

Francesco 1 

1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, 

ITALY 

2 Department of Physics, University of Milano-Bicocca, ITALY 

O93 

NONINVASIVE IMAGING OF GLYCAN-DEPENDENT TUMOR METASTASIS 

THROUGH LIVE CELL LABELING BY AZAELECTROCYCLIZATION 

Tanaka, Katsunori 1 ; Moriwaki, Kenta3 ; Nakagawa, Tsutomu 3 ; Yokoi, Satomi 4 ; 

Koyama, Koichi 4 ; Miyoshi, Eiji 3 ; Fukase, Koichi 2 


2 Department of Chemistry, Graduate School of Science, Osaka University, 

JAPAN 

3 Department of Molecular Biochemistry and Clinical Investigation, Osaka 

University, JAPAN 

4 Kishida Chemical Co., Ltd, JAPAN 

Young investigator session 

O94 

ENZYMATIC SYNTHESIS OF ACARVIOSYL-MALTOOLIGOSACCHARIDES 

AND THEIR INHIBITORY EFFECTS ON α-GLUCOSIDASE 

Tagami, Takayoshi; Tanaka, Yoshiyuki; Mori, Haruhide; Okuyama, Masayuki; 

Kimura, Atsuo 

Resarch Faculty of Agriculture, Hokkaido University, JAPAN 

O95 

MODULATING THE STRUCTURE OF SOFT MATERIALS WITH 

ASPARTAMIDE GLYCOLIPD MIMETICS 

Velasco-Torrijos, Trinidad; Abbey, Lorna; Migas, Urszula; McManus, Jennifer 

National University of Ireland Maynooth, IRELAND 

Madrid, Spain

July 22-27, 2012. 

O96 

SYNTHESIS AND FUNCTION OF SUGAR COATED LANTHANIDE 

NANOPARTICLES FOR NEAR-INFRARED PHOTODYNAMIC THERAPY 

Shimoyama, Atsushi 1 ; Watase, Hiroya1 ; Ikejiri, Takuma 1 ; Osawa, Sho 1 ; Ogura, 

Shun-ichiro 1 ; Hagiya, Yuichiro 1 ; Takahashi, Kiwamu 2 ; Inoue, Katsushi 2 ; 

Tanaka, Toru 2 ; Yuasa, Hideya 1 

1 Graduate School of Bioscience and Biotechnology, Tokyo Institute of 

Technology, JAPAN 

2 SBI Pharmaceuticals Co., Ltd., JAPAN 



FLASH 

F85 

THE USE OF NOVEL GLYCOSYL DONOR WITH TRIFLUOROACETYL 

PROTECTING GROUPS IN 1,2-CIS-ARABINOFURANOSYLATION 

Abronina, Polina 1 ; Fedina, Ksenia1,2 ; Podvalnyy, Nikita 1 ; Zinin, Alexander 1 ; 

Torgov, Vladimir 1 ; Kononov, Leonid 1 

1 N. D. Zelinsky Institute of Organic Chemistry, RUSSIA 

2 The Higher Chemical College of the Russian Academy of Sciences, RUSSIA 

F86 

PROTECTING-GROUP-FREE SYNTHESIS OF PIPERIDINE AZASUGARS 

Corkran, Hilary 1,2 ; Dangerfi eld, Emma1,2 ; Munneke, Stefan 1,2 ; 

Stocker, Bridget 1 ; Timmer, Mattie 2 


2 Victoria University of Wellington, NEW ZEALAND 

F87 

ANOMERISATION OF GLYCOSIDIC LINKAGES USING TITANIUM(IV) 

CHLORIDE 

Farrell, Mark; Murphy, Paul V. 

NUI, Galway, IRELAND 


Session 22. Glycobiology and Glycomedicine Young Investigator 

FLASH 

F88 

MOLECULAR RECOGNITION OF CELL SURFACE GLYCOSAMINOGLYCANS 

BY EOSINOPHIL CATIONIC PROTEIN. STRUCTURAL CLUES FOR ITS 

CYTOTOXIC ACTIVITY. 

García Mayoral, María Flor 1 ; Canales, Ángeles2 ; López Prados, Javier 3 ; Nieto, 

Pedro Manuel 3 ; Jesús, Jiménez Barbero 2 ; Bruix, Marta 1 



3 Instituto de Investigaciones Químicas, CSIC/Universidad de Sevilla, SPAIN 

53 

TUESDAY 24

TUESDAY 24 

54 

F89 

sp2-IMINOSUGAR N-, S- AND C-GLYCOSIDES AS SELECTIVE INHIBITORS 

OF NEUTRAL ALPHA-GLUCOSIDASES: EFFECT IN THE PROGRESSION 

OF HUMAN BREAST CANCER CELLS 

Rísquez Cuadro, Rocío 1 ; Sánchez Fernández, Elena Mathilde2 ; Allan, Ghada 

3 1 3 3 

; Ortiz Mellet, Carmen ; Ahidouch, Ahmed ; Ouadid-Ahidouch, Halima 

1 Facultad de Química, Universidad de Sevilla, SPAIN 

2 Instituto de Investigaciones Químicas, CSIC-Univ. de Sevilla, SPAIN 

3 Lab. de Physiologie Cellulaire et Moléculaire, Fac. des Sciences, Amiens, 

FRANCE 

F90 

STRUCTURAL FEATURES OF SYNTHETIC HEPARIN LIKE TRISACCHARIDE 

MODELS : SULFATION PATTERN DEFINES L-IdoA2S PLASTICITY 

Muñoz García, Juan Carlos 1 ; Angulo Álvarez, Jesús1 ; López Prados, Javier 

1 1 2 2 ; de Paz Carrera, José Luís ; Reichardt, Niels ; Martín Lomas, Manuel ; 

Corzana López, Francisco 3 ; Nieto Mesa, Pedro Manuel 1 

1 Instituto de Investigaciones Químicas (CSIC-US), SPAIN 

2 CIC-BiomaGUNE, SPAIN 

3 Universidad de la Rioja, SPAIN 

18.45-19.00 Room 3: Hidalgo 


FLASH 

F91 

CONFORMATIONAL FLEXIBILITY AND HYDROGEN BONDING OF XYLOSE 

DERIVATIVES, STUDIED BY NMR SPECTROSCOPY 

Rönnols, Jerk 1 ; Siegbahn, Anna2 ; Ochocinska, Agata 2 ; Ellervik, Ulf 2 ; Widmalm, 

Göran 1 

1 Stockholm University, Department of Organic Chemistry, SWEDEN 

2 Lund University, Department of Chemistry, SWEDEN 

F92 

PRACTICAL SYNTHESIS OF KEY CHIRAL EPOXIDE INTERMEDIATES 

FOR PROTEASE INHIBITORS FROM L-ASCORBIC ACID 

Kim, B. Moon 1 ; So, Soon Mog1 ; Lee, Sang Min 1 ; Seol, Kyoung Mi 2 ; Kang, 

Jaesung 2 ; Chang, Soon Ki 2 ; Kim, Min Kyu 3 

1 Seoul National University, SOUTH KOREA 

2 Samchully Pharmaceutical Co., Ltd, SOUTH KOREA 

3 Chonnam National University, SOUTH KOREA 

F93 

SYNTHESIS OF ALKYL DEOXY PENTOPYRANOSIDES AND THEIR 

POTENTIAL APPLICATION AS ANTIMICROBIAL AGENTS 

Serra, Patrícia; Cachatra, Vasco; Martins, Alice; Rauter, Amélia Pilar 

Faculdade de Ciências da Universidade de Lisboa, PORTUGAL 

Madrid, Spain

18.45-19.00 Room 4: Doblón 

July 22-27, 2012. 

Session 24. Glycomaterials: Synthesis and Applications. 

FLASH (Young Investigator ) 

F94 

SCREENING TOOLS FOR ARABINOXYLAN-ACTING ENZYMES 

Fauré, Régis; Borsenberger, Vinciane; Ferreira, Fernando; Bozonnet, Sophie ; 

Dumon, Claire; O’Donohue, Michael J. 

LISBP, FRANCE 

F95 

MICROENCAPSULATION OF ß-GALACTOSIDASE BY A SPRAY-DRYING 

PROCESS 

Estevinho, Berta 1 ; Damas, Ana Margarida2 ; Rocha, Fernando 1 ; Martins, Pedro2 1 FEUP-Faculdade de Engenharia da Universidade do Porto, PORTUGAL 

2 ICBAS-Instituto de Ciências Biomédicas Abel Salazar da Universidade do 

Porto, PORTUGAL 

F96 

FLUORESCENT URIDINE DIPHOSPHO-SUGAR ANALOGUES AS 

MOLECULAR PROBES 

Tedaldi, Lauren 1 ; Pesnot, Thomas2 ; Wagner, Gerd 1 

1 King’s College London, London, UNITED KINGDOM 

2 University of East Anglia, Norwich, UNITED KINGDOM 

55 

TUESDAY 24

WEDNESDAY 25 

Wednesday 25 


56 

Plenary 7 

Enzymatic synthesis of polysaccharides in lactobacilli 

L. Dijkhuizen (Groningen) University Of Groningen 

Chair: J. P. Kamerling (Groningen) 

09.15-10:00 Room 1: Auditorium 

Plenary 8 

Functional Glycans and Glycoconjugates of Human Milk 

B. Stahl (Friedrichsdorf), Danone Research Centre for Specialised Nutrition 

Chair: R. Field (Norwich) 

10.00-11.00 Coffee - Poster 


Session 25. Glycobiology, Glycomics and Glycoinformatics 

INV. 25. Array Based Glycomics: Tools and Applications 

N. C. Reichardt (San Sebastián), Biofunctional Nanomaterials Unit, 

CICbiomaGUNE 

Chairs: O. Hindsgaul (Copenhagen) Y. Knirel (Moscow) 


Session 26 Chemical Glycobiology 

INV. 26. Synthetic core and lipid A derivatives as biomolecular probes for 

LPS-protein interactions 

P. Kosma (Wien), Dept. Chemistry, University Of Natural Resources And Life 

Sciences 

Chairs: A. Molinaro (Napoli), L. Cipolla (Milano) 

11:00-11:30 Room 3: Hidalgo 

Session 27. Glicobiology, NMR and molecular recognition 

INV. 27. On the Use of 1H-1H, 13C-1H and 13C-13C NMR Spin-Couplings 

in Methyl [13C] Idohexopyranosides to Investigate Conformational 

Flexibility in Solution 

A. S. Serianni (Notre Damme, Indiana), University Of Notre Dame 

Chairs: A. Silipo (Napoli), C. Unverzagt (Bayreuth) 

Madrid, Spain

11:00-11:30 Room 4: Doblón 

July 22-27, 2012. 

Session 28 Glycobiology and Glycomaterials 

INV. 28. Catalytic mechanisms of glycosyltransferases. Insight from QM/ 

MM calculations 

I. Tvaroska (Bratislava) Institute of Chemistry, Slovak Academy of Sciences 

Chairs: S. Martín Santamaría (Madrid), A. Imberty (Grenoble) 


Session 25. Glycobiology, Glycomics and Glycoinformatics. 


O97 

DEVELOPMENT OF A NEW DETECTION PROBE FOR SIALO-GLYCANS 

WITH SIAα2-3 

Yamaguchi, Maho; Hidari, Kazuya; Suzuki, Takashi 

Department of Biochemistry, University of Shizuoka, School of Pharmaceutical 

Sciences, and Global COE Program, JAPAN 

O98 

DEVELOPMENT OF A FRET-BASED ASSAY FOR LIMIT DEXTRINASE 

ACTIVITY 

Bøjstrup, Marie; Hindsgaul, Ole; S. Windahl, Michael 

Carlsberg Laboratory, DENMARK 

O99 

PAVING THE WAY TOWARDS LABEL FREE QUANTITATIVE 

GLYCOPROTEOMICS: THE INFLUENCE OF GLYCOSYLATION AND 

ENZYMATIC DE-GLYCOSYLATION IN ESI- AND MALDI IONISATION 

EFFICIENCY 

Stavenhagen, Kathrin 1, 2 ; Thaysen-Andersen, Morten3 ; Hinneburg, Hannes 1 ; 

Mosca, Simone 1 ; Hartmann, Laura 1 ; Varón Silva, Daniel 1 ; Rapp, Erdmann 2 ; 

Seeberger, Peter H. 1,4 ; Kolarich, Daniel 1 

1 Max Planck Institute of Colloids and Interfaces, Potsdam, GERMANY 

2 Max Planck Institute of Complex Technical Systems, Magdeburg, GERMANY 

3 Macquarie University, Sydney, AUSTRALIA 

Free University Berlin, Berlin, GERMANY 

O100 

GLYCOMIC ANALYSIS AND GLYCOENGINEERING OF CHO-K1, BHK- 

21, HEK293, COS-7 AND 3T3 TOWARDS THE PRODUCTION OF HIGHLY 

SIALYLATED GLYCOPROTEINS 

Zhang, Peiqing; Wan, Corrine; Teo, Gavin; Song, Zhiwei; Bardor, Muriel 

Bioprocessing Technology Institute, SINGAPORE 

57 

WEDNESDAY 25

WEDNESDAY 25 

58 

O101 

COMBINATION OF FLUORESCENCE AND MALDI-IMAGING READOUT IN 

A SINGLE PLATFORM BASED ON HYDROPHOBIC INTERACTIONS 

Beloqui, Ana; Calvo, Javier; Martin-Lomas, Manuel; Reichardt, Niels-Christian 

CICBiomagune, San Sebastian, SPAIN 


Session 26. Chemical Glycobiology. 


O102 

PREPARATION AND IMMUNOLOGICAL ACTIVITY OF 

NEOGLYCOCONJUGATE WITH PLANT ANTIGENIC N-GLYCANS 

Maeda, Megumi 1 ; Mano, Aya2 ; Yamanishi, Maomi 2 ; Otsuki, Takemi 3 ; Okano, 

Mitsuhiro 4 ; Kimura, Yoshinobu 1 

1 Department of Biofunctional Chemistry, Okayama University Graduate School 

of Environmental and Life Science, Okayama, JAPAN 

2 Faculty of Agriculture, Okayama University, Okayama, JAPAN 

3 Department of Hygiene, Kawasaki Medical School, Kurashiki, JAPAN 

4 Department of Otolaryngology, Okayama University Graduate School of 

Medicine, Dentistry and Pharmaceutical Sciences, Okayama, JAPAN 

O103 

GLYCOLIPDS AND THEIR ROLE IN DISEASE: FROM ANTI-CANCER 

VACCINES TO BACTERIAL INFECTION 

Stocker, Bridget 1 ; Dangerfi eld, Emma1,2 ; Sauvageau, Janelle 1,2,3 ; 

Cheng, Janice 1,2 ; Knight, Deborah 1 ; Weinkove, Rob 1 ; Dunbar, Rod 4 ; 

Hermans, Ian 1 ; 

Timmer, Mattie 2 ; 


2 School of Chemical and Physical Sciences, Victoria University of Wellington, 

NEW ZEALAND 

3 Industrial Research Ltd, NEW ZEALAND 

4 Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, 

NEW ZEALAND 

O104 

TOWARDS A VACCINE AGAINST THE PARASITE Toxoplasma gondii 

Goetze, Sebastian; Azzouz, Nahid; Tsai, Yu-Hsuan; Seeberger, Peter; Varon 

Silva, Daniel 

Max Planck Institute of Colloids and Interfaces, GERMANY 

O105 

SYNTHETIC MULTIMERIC MANNOSIDE TO PREVENT IN VITRO AND IN 

VIVO ADHESION OF TYPE 1 FIMBRIATED Escherichia coli STRAINS 

Gouin, Sébastien 1,2 

1 Laboratoire CEISAM, University of Nantes, FRANCE 

2 Laboratoire des glucides, University of Amiens, FRANCE 

Madrid, Spain

July 22-27, 2012. 

O106 

DESIGN AND SYNTHESIS OF Quillaja saponin VACCINE ADJUVANTS 

Fernandez-Tejada, Alberto; Chea, Eric; Ragupathi, Govind; Livingston, Philip; 

Gin, David 

Memorial Sloan-Kettering Cancer Center, USA 

11.30-12.45 Room 3: Hidalgo 

Session 27. Glycobiology, NMR and Molecular Recognition. 


O107 

A GENERAL SYNTHETIC STRATEGY TO OBTAIN GPI ANCHORS: NEW 

ALTERNATIVES FOR EVALUATION OF GPI FUNCTIONS 

Varon Silva, Daniel 1 ; Seeberger, Peter H. 1,2 ; Vilotijevic, Ivan 1 ; 

Tsai, Yu-Hsuan 1 ; Götze, Sebastian 1 ; Grube, Maurice 1 


2 Free University of Berlin, GERMANY 

O108 

NMR ANALYSIS OF SPECIFIC CARBOHYDRATE-CARBOHYDRATE 

INTERACTION BETWEEN GANGLIOSIDES 

Uekusa, Yoshinori 1, 2 ; Sonnino, Sandro3 ; Kato, Koichi 1,2 

1 Institute for Molecular Science and Okazaki Institute for Integrative Bioscience, 

National Institutes of Natural Sciences, JAPAN 

2 Graduate School of Pharmaceutical Sciences, Nagoya City University, JAPAN 

3 Department of Medical Chemistry, Biochemistry and Biotechnology, University 

of Milan, ITALY 

O109 

IMPROVING SATURATION TRANSFER DIFFERENCE NMR EXPERIMENTS 

OF MEMBRANE PROTEINS IN LIVING CELLS: THE INTERACTION OF THE 

SGLT1 COTRANSPORTER WITH ITS LIGANDS 

Airoldi, Cristina 1 ; Merlo, Silvia1 ; Sironi, Erika 1 ; La Ferla, Barbara 1 ; Nicotra, 

Francesco 1 ; Jiménez-Barbero, Jesús 1,2 

1 University of Milano-Bicocca, Dept. of Biotechnology and Biosciences, ITALY 


O110 

NMR INSIGHTS INTO THE MECHANISM OF MOLECULAR SELECTIVITY 

AND RECOGNITION BY CARBOHYDRATE-BINDING MODULES FROM 

Clostridium thermocellum 

Viegas, Aldino; Sardinha, João; Carvalho, Ana; Macedo, Anjos; Cabrita, Eurico 

Requimte, FCT-UNL, PORTUGAL 

59 

WEDNESDAY 25

WEDNESDAY 25 

60 

O111 

NMR STRUCTURE OF A NOVEL MUSHROOM DEFENSE LECTIN 

RECOGNIZING A NON-SELF GLYCAN 

Schubert, Mario 1 ; Bleuler-Martinez, Silvia 2 ; Butschi, Alex 3 ; 

Wälti, Martin A. 2 ; Egloff, Pascal 2 ; Stutz, Katrin 3 ; Hengartner, Michael O. 3 ; 

Aebi, Markus 2 ; Künzler, Markus 2 ; Allain, Frédéric H.-T. 1 

1 Institute of Molecular Biology and Biophysics, ETH Zurich, SWITZERLAND 

2 Institute of Microbiology, ETH Zürich, SWITZERLAND 

3 Institute of Molecular Life Sciences, University of Zürich, SWITZERLAND 

11.30-12.45 Room 4: Doblón 

Session 28. Glycobiology and Glycomaterials. 


O112 

COMPUTATIONAL STUDY OF RETAINING GLYCOSYLTRANSFERASES 

MECHANISM:FRONT SIDE ATTACK VS. DOUBLE-DISPLACEMENT 

MECHANISM 

Masgrau, Laura; Gómez, Hansel; Lluch, José M. 

Universitat Autònoma de Barcelona, SPAIN 

O113 

HIJACKING A BIOSYNTHETIC PATHWAY YIELDS A 

GLYCOSYLTRANSFERASE INHIBITOR IN CELLS 

Gloster, Tracey 1,2 ; Zandberg, Wesley2 ; Heinonen, Julia 2 ; Shen, David 2 ; Deng, 

Lehua2 ; Vocadlo, David 2 

1 University of St Andrews, UNITED KINGDOM 

2 Simon Fraser University, CANADA 

O114 

STUDIES TOWARDS PEPTIDOGLYCAN INVOLVED IN CELULAR 

RECOGNITION 

Marques, Maria 

FCT-UNL, PORTUGAL 

O115 

3D-STRUCTURES OF CARBOHYDRATES IN THE GAS PHASE 

Cocinero, Emilio J. 

Universidad del País Vasco, SPAIN 

O116 

GLYCOLIPIDS PRODUCTION USING METABOLIC ENGINEERING 

STRATEGY 

Faijes, Magda; Mora-Buyé, Neus; Planas, Antoni 

Institut Químic de Sarrià, Ramon Llull University, SPAIN 

Madrid, Spain


Session 25. Glycobiology, Glycomics and Glycoinformatics. 


F97 

COVALENT GLYCAN MICROARRAY AND BIACORE CHIPS FOR 

STUDYING LysM PROTEIN BINDING TO CHITIN, PEPTIDOGLYCAN AND 

NOD FACTORS 

Maolanon, Nicolai 1 ; Blaise, Mikael2 ; Sørensen, Kasper 1 ; Thygesen, Mikkel 1 ; 

Broghammer, Angelique 2 ; Cló, Emiliano 3 ; Ronson, Clive 4 ; Stougaard, Jens 2 ; 

Blixt, Ola 3 ; Jensen, Knud 1 

1 Center for Carbohydrate Recognition and Signalling (CARB), University of 

Copenhagen, Faculty of Life Sciences, DENMARK 

2 Center for Carbohydrate Recognition and Signalling (CARB), Aarhus 

University, DENMARK 

3 Copenhagen Center for Glycomics (CCG), University of Copenhagen, Faculty 

of Health Sciences, DENMARK 

4 Center for Carbohydrate Recognition and Signalling (CARB), University of 

Otago, NEW ZEALAND 

F98 

A NEW TETHERING SITE FOR LABELLING GLYCOLIPIDS: SYNTHESIS 

AND FUNCTIONAL ACTIVITY OF A BIOTINYLATED DERIVATIVE OF THE 

CD1d AGONIST THREITOL CERAMIDE 

Jervis, Peter 1 ; Wojno, Justyna1 ; Jukes, John-Paul 2 ; Cerundolo, Vincenzo 2 ; 

Cox, Liam1 ; Besra, Gurdyal 1 

1 University of Birmingham, UNITED KINGDOM 

2 Weatherall Institute of Molecular Medicine, Oxford, UNITED KINGDOM 

F99 

UniCarbKB: A GLYCOINFORMATICS INITIATIVE TO TACKLE THE 

CHALLENGES OF GLYCOMICS 

Campbell, Matthew 1 ; Hayes, Catherine2 ; Everest-Dass, Arun 1 ; Nguyen-Khuong, 

Terry1 ; Chandrasekaran, Archana 3 ; Wilkins, Marc 3 ; Lisacek, Frederique 4 ; 

Karlsson, Niclas2 ; Packer, Nicolle 1 

1 Biomolecular Frontiers Research Centre, Macquarie University, Sydney, 

AUSTRALIA 

2 Medical Biochemistry, University of Gothenburg, Gothenburg, SWEDEN 

3 Systems Biology Initiative, University of New South Wales, Sydney, 

AUSTRALIA 

4 Swiss Institute of Bioinformatics, Geneva, SWITZERLAND 

July 22-27, 2012. 

61 

WEDNESDAY 25

WEDNESDAY 25 

62 

F100 

COMPREHENSIVE STRUCTURAL ANALYSES OF DISACCHARIDES WITH 

UNUSUAL LINKAGE 

Gubica, Tomasz 1 ; Temeriusz, Andrzej2 ; Stêpieñ, Dorota K. 2 ; Bukowicki, 

Jaroslaw 1 ; Ostrowski, Andrzej 3 ; Pisklak, Dariusz M. 1 ; Cyrañski, MichalK. 2 

1 Medical University of Warsaw, POLAND 

2 University of Warsaw, POLAND 

3 Warsaw University of Technology, POLAND 

F101 

FROM COMPUTATIONAL STUDIES TO BIOLOGICAL RELEVANCE: 

A JOURNEY TOWARDS UNDERSTANDING THE MODULATION OF 

FUCOSYLATION REACTIONS 

Lalik, Anna; Jaksik, Roman; Rzeszowka-Wolny, Joanna 

Silesian University of Technology, POLAND 

F102 

MONOSACCHARIDE NOTATION IN GLYCOINFORMATICS: PROBLEMS, 

PITFALLS, AND SOLUTIONS 

Lütteke, Thomas 

University of Gießen, GERMANY 

F103 

CHITOSAN-CARRAGEENAN COMPLEX: AS ENCAPSULATING DEVICE 

AND SCAFFOLD 

Chakraborty, Soma 

Ateneo de Manila University, PHILIPPINES 

F104 

SYNTHESIS AND CHARACTERIZATION OF NEW HYDROGEL MATRICES 

FOR BIOMEDICAL APPLICATION 

Kavianinia, Iman 1 ; Harding, David1 ; Plieger, Paul 1 ; Kandile, Nadia 2 

1 Massey University, NEW ZEALAND 

2 Ain Shams University, EGYPT 

F105 

CHEMO-ENZYMATIC SYNTHESIS OF GLYCEROLIPIDYL-CYCLODEXTRINS 

Bonnet, Véronique 1 ; Gervaise, Cédric1,2 ; Favrelle, Audrey 1,2 ; 

Sarazin, Catherine2 ; Djedaini-Pilard, Florence 1 

1 Laboratoire Des Glucides FRE CNRS 3517, FRANCE 

2 Unité de Génie Enzymatique et Cellulaire UMR-CNRS 6022, FRANCE 

F106 

GLYCOLIPIDS FOR THE MODULATION OF SK3 CHANNEL 

Sevrain, Charlotte 1 ; Haelters, Jean-Pierre1 ; Couthon-Gourvès, Hélène1 ; 

Jaffrès, Paul-Alain1 ; Chantome, Aurélie 2 ; Vandier, Christophe2 1 UMR CNRS 6521 CEMCA, Universiré de Bretagne Occidentale, FRANCE 

2 INSERM U921, Université François Rabelais, FRANCE 

Madrid, Spain

July 22-27, 2012. 

F107 

SYNTHESIS OF PHOSPHORYLATED L-GLYCERO-D-MANNO- 

HEPTOPYRANOSIDE SUBSTRUCTURES OF BACTERIAL LPS 

Stanetty, Christian; Kosma, Paul 

University of Natural Resources and Life Sciences, AUSTRIA 


Session 26. Chemical Glycobiology. 


F108 

AUTOMATED SYNTHESIS OF GLYCOPEPTIDES BY COMBINING SOLID- 

PHASE PEPTIDE AND OLIGOSACCHARIDE SYNTHESIS 

Hurevich, Mattan; Seeberger, Peter 

Max-Planck-Institute of Colloids and Interfaces, Berlin, GERMANY 

F109 

TOTAL CHEMICAL SYNTHESIS OF A GLYCOSYL CHEMOKINE: Ser- 

CCL1 AND STRUCTURAL ANALYSIS BY QUASI-RACEMATE X-RAY 

CRYSTALLOGRAPHY 

Okamoto, Ryo 1, 3 ; Mandal, Kalyanswer1 ; Sawaya, Michael 2 ; 

Kajihara, Yasuhiro 3 ; Yeates, Todd 2 ; Kent, Stephen 3 

1 The University of Chicago, USA 

2 University of California Los Angeles, USA 

3 Osaka University, JAPAN 

F110 

MEASURMENT OF SALICYLIC ACID IN POPLAR’S BARK (P.DELTOIDES 

AND P.EURAMERICAN) BY HIGH PERFORMANCE LIQUID 

CHROMATOGRAPHY (HPLC) 

Torkaman, Javad; Seyam, Shoreh 

University of Guilan, IRAN 

F111 

STRUCTURAL FEATURES AND BIOLOGICAL ACTIVITY OF 

OLIGOSACCHARIDES LINKED TO STORAGE GLYCOPROTEINS IN 

EDIBLE BEANS. 

Kimura, Mariko 1 ; Nagasawa, Haruko2 ; Maeda, Megumi 3 ; Kimura, Yoshinobu 3 

1 Faculty of Food Culture, Kurashiki Sakuyo University, Okayama, JAPAN 

2 Faculty of Home Economics, Kobe Woman’s University, Kobe, JAPAN 

3 Graduate School of Environmental and Life Science, Okayama University, 

Okayama, JAPAN 

63 

WEDNESDAY 25

WEDNESDAY 25 

64 

F112 

COMPARATIVE INVESTIGATION OF THE SIALYLATION POTENTIAL OF 

THE CLOSELY RELATED HUMAN CELL LINES HEK-293 AND HEK-293T 

Rosenlöcher, Julia 1 ; Mokros, Myriam1 ; Reinke, Stefan 1 ; Berger, Markus 2 ; 

Hinderlich, Stephan 1 

1 Beuth University of Applied Sciences Berlin, Department of Life Sciences and 

Technology, Berlin, GERMANY 

2 Charité-Universitätsmedizin Berlin, Institute of Laboratory Medicine, Clinical 

Chemistry and Pathobiochemistry, Glycodesign and Glycoanalytics, Berlin, 

GERMANY 

F114 

SUGAR-MODIFIED NUCLEIC ACIDS: EXPLORING THE ROLE OF 

CHIRALITY IN MOLECULAR RECOGNITION AND FUNCTION 

D’Alonzo, Daniele; Guaragna, Annalisa; Palumbo, Giovanni 

University of Napoli, ITALY 

F115 

SYNTHESIS OF NEW GLYCODENDRIMERS BY CLICK CHEMISTRY AND 

BINDING STUDIES 

Aires, A. 1,2 ; Muelas, D. 1,2 ; Bañón, C, 1 ; Treviño, J. 1 ; Ardá, A. 3 ; 

Jiménez-Barbero, J. 3 ; Rumbero, A. 2 ; Hernaiz, M.J. 1 

1 Department of Organic and Pharmaceutical Chemistry, Faculty of Pharmacy, 

Complutense University, Madrid, SPAIN 

2 Department of Organic Chemistry, Faculty of Science, Autonoma University of 

Madrid, SPAIN 

3 Chemical and Physical Biology, Centro de Investigaciones Biológicas, CSIC, 

Madrid, SPAIN 

F116 

DYNAMIC MULTIVALENCY FOR THE RECOGNITION OF PROTEIN 

SURFACES 

Reeh, Philipp; de Mendoza, Javier 

Institute of Chemical Research of Catalonia (ICIQ), Tarragona, SPAIN 

F117 

ONE-ON-ONE WITH CHOLERA TOXIN: PENTAVALENT GANGLIOSIDE 

CALIXARENES 

Wennekes, Tom 1 ; Garcia Hartjes, Jaime1 ; Bernardi, Silvia 2 ; Weijers, Carel 1 ; 

Casnati, Alessandro 2 ; Zuilhof, Han 1 

1 Wageningen University, Laboratory of Organic Chemistry, NETHERLANDS 

2 Università degli Studi di Parma, Dipartimento di Chimica Organica e Industriale, 

ITALY 

F118 

CHEMICAL SYNTHESIS OF AN ERYTHROPOIETIN GLYCOFORM 

CONTAINING A COMPLEX-TYPE DISIALYLOLIGOSACCHARIDE 

Murakami, Masumi; Okamoto, Ryo; Izumi, Masayuki; Kajihara, Yasuhiro 

Osaka University, JAPAN 

Madrid, Spain

12.45-13.45 Room 3: Hidalgo 

July 22-27, 2012. 

Session 27. Glycobiology, NMR and Molecular Recognition. 


F119 

SCREENING FOR SURFACE BINDING SITES IN CARBOHYDRATE ACTIVE 

ENZYMES 

Cockburn, Darrell 1 ; Wilkens, Casper1 ; Jespersen, Susan 1 ; Abou Hachem, 

Maher 1 ; Ruzanski, Christian 2,3 ; Smith, Alison 3 ; Svensson, Birte 1 

1 Technical University of Denmark, DENMARK 

2 Carlsberg Laboratories, Copenhagen, DENMARK 

3 John Innes Center, Norwich, ENGLAND 

F120 

GLYCONUTRITIONAL DIETARY SUPPLEMENT FROM PLANT 

CARBOHYDRATES 

Kharkwal, Harsha 1 ; Pant, Manish2 ; Joshi, Devi Datt 2 

1 Amity Center for Carbohydrate Research, INDIA 

2 Amity Institute of Phytochemistry and Phytomedicine, INDIA 

F121 

ENZYMATIC TOOLS FOR THE DEPOLYMERIZATION OF MARINE 

BACTERIAL EXOPOLYSACCHARIDES 

Florian, Lelchat 1 ; Anne-Claire, Baudoux2 ; Christophe, Brandilly 1 ; Sophie, 

Schmitt 1 ; Joelle, Cozien 1 ; Andrea, Leroy 1 ; Sylvia, Colliec Jouault 1 ; Claire, 

Boisset 1 

1 Ifremer, FRANCE 

2 Station Biologique de Roscoff, FRANCE 

F122 

SIMULTANEOUS EXTRACTION AND FRACTIONATION OF COFFEE 

RESIDUE CARBOHYDRATES USING MICROWAVE ASSISTED 

EXTRACTION 

Passos, Claudia; Coimbra, Manuel 

Universidade de Aveiro, PORTUGAL 

F123 

GOLD GLYCONANOPARTICLES AS TARGETED MOLECULAR DELIVERY 

SYSTEMS 

Aykaç, Ahmet; Martos Maldonado, Manuel C.; Quesada Soriano, Indalecio; 

García Fuentes, Luis; Vargas Berenguel, Antonio 

University of Almeria, SPAIN 

F124 

PURINE NUCLEOSIDES AS SELECTIVE INHIBITORS OF HUMAN 

BUTYRYLCHOLINESTERASE 

Schwarz, Stefan; Teixeira, Vitor Hugo; Machuqueiro, Miguel; Rauter, Amélia 

Pilar Universidade de Lisboa, DQB, PORTUGAL 

65 

WEDNESDAY 25

WEDNESDAY 25 

66 

F125 

THE SYNTHESIS OF DANSYL α-GALACTOSYLCERAMIDE: A 

FLUORESCENT PROBE TO TRACK GLYCOLIPID UPTAKE DURING 

CANCER IMMUNOTHERAPY 

Cheng, Janice 1 ; Chee, Stephanie1 ; Knight, Deborah 1 ; Hermans, Ian 1 ; Timmer, 

Mattie 2 ; Stocker, Bridget 1 


2 Victoria University of Wellington, NEW ZEALAND 

F126 

TOWARDS THE DEVELOPMENT OF A GLYCOCONJUGATE VACCINE 

AGAINST Cryptococcus neoformans 

Guazzelli, Lorenzo; Ulc, Rebecca; Oscarson, Stefan 

University College Dublin, IRELAND 

F127 

DEVELOPMENT OF A Streptococcus pneumoniae CONJUGATE VACCINE 

AGAINST SEROTYPE 1 DISEASE. 

Edmonds-Smith, Cesarina 1,2 ; Mohamed, Ebrahim2 ; Wilson, Seanette 2 ; 

Ravenscroft, Neil 1 

1 University of Cape Town, SOUTH AFRICA 

2 The Biovac Institute, SOUTH AFRICA 

F128 

SYNTHESIS AND GENE TRANSFER CAPABILITIES OF CYCLIC 

POLYAMINE-GRAFTED AMPHIPHILIC CYCLODEXTRINS 

Rodriguez-Lucena, David 1 ; Pfl ueger, Iris1 ; Méndez-Ardoy, Alejandro 2 ; Benito, 

Juan M. 1 ; Ortiz Mellet, Carmen 2 ; García Fernández, José M. 1 

1 Instituto de Investigaciones Quimicas, CSIC-Universidad de Sevilla, SPAIN 

2 Dpto. de Química Orgánica, Facultad de Química, Universidad de Sevilla, 

SPAIN 

F129 

DEPLETION OF MULTIDRUG TRANSPORTER PROTEIN ON CANCER 

CELLS CAUSED BY LECTIN-GLYCOSPHINGOLIPID INTERACTION 

ENHANCED THE CHEMOTHERAPUTIC EFFECTS 

Fujii, Yuki 1,2,3 ; Sugawara, S. 2 ; Nitta,, K. 2 ; Hosono, M. 2 ; Tatsuta, T. 2 ; 

Ogawa, Y. 3 ; Kawsar, S. M. A. 1,4 ; Matsumoto, R. 1 ; Koide, Y. 1 ; Hasan, I. 1 ; 

Hakomori,, S-I 2,5 ; Ozeki, Y. 1 

1 Laboratory of Glycobiology and Marine Biochemistry, Graduate School of 

NanoBio Sciences, Yokohama City University, Yokohama, JAPAN 

2 Divisions of Cell Recognition Study, Institute of Molecular Biomembrane and 

Glycobiology, Tohoku Pharmaceutical University, Sendai, JAPAN 

3 Sections of Functional Morphology and Micorbiology, Faculty of Pharamaceutical 

Sciences, Nagasaki International University, Sasebo, Nagasaki, JAPAN 

4 Department of Chemistry, Graduate School of Sciences, University of 

Chittagong, Chittagong, BANGLADESH 

5 Division of Biomembrane Research, Pacifi c Northwest Research Institute, 

Broadway, Seattle, USA 

Madrid, Spain

12.45-13.45 Room 4: Doblón 

Session 28. Glycobiology and Glycomaterials. 


F130 

IN SILICO PROTEIN ENGINEERING - GOOD SERVANT BUT BAD MASTER 

Adamova, Lenka; Adam, Jan; Pokorna, Martina; Demo, Gabriel; Koca, Jaroslav; 

Wimmerova, Michaela 

Masaryk University, CZECH REPUBLIC 

F131 

A NOVEL CYCLOISOMALTOOLIGOSACCHARIDE 

GLUCANOTRANSFERASE from Paenibacillus sp. 598K 

Funane, Kazumi 1 ; Suzuki, Ryuichiro1,2 ; Kimura, Keitarou 1 ; Fujimoto, Zui 3 ; 

Momma, Mitsuru 3 ; Kobayashi, Mikihiko 4 ; Kimura, Atsuo 5 

1 National Food Research Institute, National Agriculture and Food Research 

Organization, JAPAN 

2 Akita Prefectural University, JAPAN 

3 Biomolecular Research Unit, National Institute of Agrobiological Sciences, 

JAPAN 

4 Jissen Women’s University, JAPAN 

5 Hokkaido University, JAPAN 

F132 

β -GLUCOSYLTRANSFERASES FROM PROTEOBACTERIA CATALYZE 

THE DISPROPORTIONATION OF LINEAR (β 1 → 3)-LINKED GLUCO- 

OLIGOSACCHARIDE CHAINS 

Dobruchowska, Justyna 1 ; Gerwig, Gerrit1 ; Hreggvidsson, Gudmundur 2,3 ; 

Jonsson, Jon 2 ; Fridjonsson, Olafur 2 ; Curti, Delphine 4 ; Redgwell, Robert 4 ; 

Dijkhuizen, Lubbert 1 ; Kamerling, Johannis 1 

1 Univeristy of Groningen, NETHERLANDS 

2 Matís Ltd, Reykjavík, ICELAND 

3 Department of Biology, University of Iceland, Reykjavík, ICELAND 

4 Nestlé Research Center, Lausanne , SWITZERLAND 

F133 

STRUCTURAL INSIGHT IN HISTO-BLOOD GROUP BINDING BY THE 

FIMBRIAL ADHESIN FEDF REVEALS AN ADDITIVE BINDING MECHANISM 

THAT STEERS SPECIFICITY TOWARDS GLYCOLIPIDS 

Moonens, Kristof 1,2 ; Bouckaert, Julie 1,2 ; de Kerpel, Maia 1,2 ; 

Coddens, Annelies 3 ; Cox, Eric3 ; Thran, Thao 1,2 ; Remaut, Han1,2 ; de Greve, 

Henri 1,2 

1 Structural & Molecular Microbiology, Department of Molecular and Cellular 

Interactions, VIB, Brussels, BELGIUM 

2 Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, BELGIUM 

3 Department of Veterinary Immunology, Faculty of Veterinary Medicine, Ghent 

University, BELGIUM 

July 22-27, 2012. 

67 

WEDNESDAY 25

WEDNESDAY 25 

68 

F134 

SYSTEMATIC SYNTHESIS OF N-GLYCAN DERIVATIVES USING INVERSION 

OF C-2 HYDROXYL GROUP 

Iwamoto, Shogo 1 ; Kenta, Iino1 ; Kasahara, Yuta 1 ; Ito, Yukishige 2,3 ; Matsuo, 

Ichiro 1 

1 Graduate School of Engineering, Gunma University, JAPAN 


3 ERATO Glycotrilogy Project, JST, JAPAN 

F135 

STRUCTURE-FUNCTION ANALYSIS OF REOVIRUS ATTACHMENT 

PROTEIN SIGMA 1 ESTABLISHES THE GM2 GLYCAN AS A CO-RECEPTOR 

FOR TYPE 1 REOVIRUSES 

Reiss, Kerstin 1 ; Stencel, Jennifer2 ; Blaum, Bärbel 1 ; Reiter, Dirk 1 ; Liu, Yan 3 ; 

Feizi, Ten 3 ; Dermody, Terence 2 ; Stehle, Thilo 1,2 

1 University of Tuebingen, Interfaculty Institute of Biochemistry, GERMANY 

2 Department of Pediatrics, Vanderbilt University School of Medicine, USA 

3 Glycosciences Laboratory, Faculty of Medicine, Imperial College London, 

UNITED KINGDOM 

F136 

SINGLE AMINO ACID EXCHANGE IN BACTERIOPHAGE HK620 

TAILSPIKE PROTEIN RESULTS IN THOUSAND FOLD INCREASE OF ITS 

OLIGOSACCHARIDE AFFINITY 

Barbirz, Stefanie 1 ; Broeker, Nina K. 1 ; Gohlke, Ulrich 2 ; Mueller, Juergen J. 2 ; 

Uetrecht, Charlotte 1 ; Heinemann, Udo 2 ; Seckler, Robert 1 

1 University of Potsdam, GERMANY 

2 Max-Delbrueck-Center for Molecular Medicine Berlin, GERMANY 

F137 

MOLECULAR RECOGNITION AND IMMUNITY: MOLECULAR MODELLING 

OF TOLL-LIKE RECEPTOR 4 MODULATORS. 

Pinilla, José Antonio; Martín-Santamaría, Sonsoles 

Faculty of Pharmacy, Universidad San Pablo CEU, Madrid, SPAIN 

F138 

LAMELLAR PHASES INCLUDING A CALIXARENE-BASED GLUCOSE 

FUNCTIONALIZED BOLAAMPHIPHILE FOR MULTIVALENT RECOGNITION 

Sansone, Francesco 1 ; Aleandri, Simone2 ; Casnati, Alessandro 1 ; Mancini, 

Giovanna 2,3 ; Rispoli, Gabriele 1 

1 Dipartimento di Chimica Organica e Industriale, Università degli Studi di 

Parma, ITALY 

2 Dipartimento di Chimica, Università degli Studi di Roma ‘Spienza’, ITALY 

3 CNR, Istituto di Metodologie Chimiche, ITALY 

Madrid, Spain

July 22-27, 2012. 

F139 

MODULATION OF PROSTACYCLIN SECRESION BY DIETARY 

POLYSULFATED POLYSACCHARIDE F-FUCOIDAN IN HUMANS 

Kanazawa, Kazuki 1 ; Ren, Reng1 ; Hashimoto, Takashi 1 ; Nishitani, Yosuke1 ; 

Mizuno, Masashi 1 ; Ojima, Takao 2 ; Yoshida, Masaru 3 ; Azuma, Takeshi 3 

1 Graduate School of Agricultural Science, Kobe University, JAPAN 

2 Graduate School of Fisheries Science, Hokkaido University, JAPAN 

3 Department of Internal Medicine, Kobe University, JAPAN 

F140 

GAS PHASE STUDY OF HUMAN ACID ß-GLUCOSIDASE AND IMINOSUGAR 

PHARMACOLOGICAL CHAPERONES 

Rajabi, Negar; Douglas, Don 

University of British Columbia, CANADA 

69 

WEDNESDAY 25

THURSDAY 26 

Thursday 26 


70 

Plenary 9 

The chemical glycobiology of microbial pathogen interactions 

M. Von Itzstein (Gold Coast), Griffi th University 

Chair: T. Peters (Lubeck) 


Session 29 Enzymes: from Mechanisms to Applications 

INV. 29. Chemical biology of O-GlcNAc-enzyme mechanism to roles in 

disease 

D. Vocadlo (Burnaby), Simon Fraser University 


Chairs: A. Planas (Barcelona), S. Withers (Vancouver) 

Session 30 Glycobiology 

INV. 30. Carbohydrate manipulation of the human gut microbiome 

R.Rastall (Reading), Department of Food and Nutritional Sciences, The 

University of Reading 

Chairs: C. De Castro (Napoli), L. Mulard (Paris) 

09:20-09:50 Room 3: Hidalgo 

Session 31. Chemical Glycobiology 

INV. 31. Nucleic acid encoding to program the assembly of glycan 

fragments with controlled geometry 

N. Winssinger (Strasbourg), Institut De Science Et D’Ingénierie 

Supramoléculaires (ISIS), Université De Strasbourg - CNRS 

Chairs: D. Werz (Göttingen), S. Williams (Parkville) 

09:20-09:50 Room 4: Doblón 

Session 32. Structural Glycobiology 

INV. 32. Virtual Glycan Array Screening for Specifi city Prediction: 

Application to Carbohydrate-Binding Proteins and Enzymes 

R.Woods (Galway), Complex Carbohydrate Research Center, University of 

Georgia / School of Chemistry, National University of Ireland 

Chairs: A.Serianni (Notre Damme, Indiana), A. Airoldi (Milan) 

Madrid, Spain


July 22-27, 2012. 

Session 29. Enzymes: from Mechanisms to Applications 

ORAL 

O117 

THE MOLECULAR MECHANISM OF ENZYMATIC GLYCOSYL TRANSFER 

WITH RETENTION OF CONFIGURATION: EVIDENCE FOR A SHORT-LIVED 

OXOCARBENIUM ION-LIKE SPECIES 

Rovira, Carme 1 ; Ardèvol, Albert2 1 ICREA / Parc Científi c de Barcelona, SPAIN 

2 Parc Científi c de Barcelona, SPAIN 

O118 

CARBOHYDRATE-DERIVED SYNTHETIC MOLECULES ACTIVE ON 

ENDOTOXIN/TLR4 SIGNALING 

Peri, Francesco 1 ; Granucci, Francesca1 ; Weiss, Jerry 2 ; Gioannini, Theresa 2 ; 

Ciaramelli, Carlotta 2 ; Cighetti, Roberto 2 ; Sestito, Stefania 2 ; Piazza, Matteo 2 

1 Department of Biotechnology and Biosciences, University Milano Bicocca, 

ITALY 

2 Infl ammation Program, University of Iowa, Iowa City, USA 


Session 30. Glycobiology 

ORAL 

O119 

SYNTHESIS OF PREBIOTIC GALACTOOLIGOSACCHARIDES CATALYZED 

BY BETA-GALACTOSIDASES FROM DIFFERENT MICROORGANISMS 

Plou, Francisco 1 ; Rodriguez-Colinas, Barbara1 ; Fernandez-Arrojo, Lucía 1 ; de 

Abreu, Miguel 2 ; Urrutia, Paulina 1,3 ; Poveda, Ana 4 ; Jiménez-Barbero, Jesús 5 ; 

Illanes, Andres3 ; Fernandez-Lobato, Maria 2 ; Ballesteros, Antonio O. 1 

1 Institute of Catalysis, CSIC, SPAIN 

2 Centro de Biología Molecular Severo Ochoa, CSIC-UAM, SPAIN 

3 School of Biochemical Engineering, Pontifi cia Universidad Católica de 

Valparaiso, CHILE 

4 Servicio Interdepartamental de Investigación, UAM, Madrid, SPAIN 


O120 

A NEUTRAL-DRIFT BASED APPROACH FOR THE GENERATION OF 

POLYMORPHIC VARIANTS LIBRARY OF Neisseria polysaccharea 

AMYLOSUCRASE 

Daudé, David; Cambon, Emmanuelle; Vergès, Alizée; Emond, Stéphane; 

Tarrat, Nathalie; André, Isabelle; Remaud-Siméon, Magali 

Laboratoire D’Ingénierie des Systèmes Biologiques et des Procédés-INSA, 

UMR CNRS 5504, INRA 792, Université de Toulouse, FRANCE 

71 

THURSDAY 26


09.50-10.20 Room 3: Hidalgo 

Session 31. Chemical Glycobiology. 


O121 

DISCOVERY OF NIGEROSE PHOSPHORYLASE FROM Clostridium 

phytofermentans 

Nakai, Hiroyuki 1 ; Nihira, Takanori 1 ; Chiku, Kazuhiro 2 ; Kitaoka, Motomitsu 2 

1 Graduate School of Science and Technology, Niigata University, JAPAN 

2 National Food Research Institute, National Agriculture and Food Research 

Organization, JAPAN 

O122 

TERMINALLY MODIFIED MANNOSIDES AS HIGH-AFFINITY INHIBITORS 

OF Pseudomonas aeruginosa LECTIN LECB 

Titz, Alexander; Hauck, Dirk; Frommeyer, Benjamin; Furones, Beatriz; Möller, 

Heiko M.; Exner, Thomas 

University of Konstanz, Department of Chemistry & Zukunftskolleg, GERMANY 

09.50-10.20 Room 4: Doblón 

Session 32 Oral Communications. Structural Glycobiology 

O123 

CONTINUUM SOLVATION EXPLAINS DIFFERENCE BETWEEN THE 

VACUUM AND CONDENSED PHASE CONFORMATIONS OF CELLOBIOSE 

French, Alfred 1 ; Johnson, Glenn1 ; Cramer, Christopher 2 ; Csonka, Gabor 

1 U.S. Department of Agriculture, USA 

2 University of Minnesota, USA 

3 Budapest University of Technology and Economics, HUNGARY 

O124 

REDESIGNING CARBOHYDRATE SYMBOLS 

Kuttel, Michelle; Sharwood, Brett 

Department of Computer Science, University of Cape Town, SOUTH AFRICA 

10:20-11:30 Coffee-Poster 


Session 33. 

INV. 33. Homogeneous Glycoproteins: Design, Chemical Synthesis and 

Biological Evaluation 

Y. Kajihara (Toyonaka) Dept. Of Chemistry, Osaka University 

72 

Chairs: N. Ravenscroft (Cape Town), A. P. Rauter (Lisboa) 

Madrid, Spain


Session 34. 

INV. 36. Anti-Adhesion Therapy for Urinary Tract Infections-A Balanced 

PK/PD-Profi le Proved to be Key for Success 

B. Ernst (Basel) University Of Basel Institut For Molecular Pharmacy 

July 22-27, 2012. 

Chairs: M. Sollogoup (`Paris), J. I. Karokawa (Kagoshima) 

11:30-12:00 Room 4: Doblón 

Session 35. 

INV. 39. Structure, dynamics and interactions of carbohydrates by 

biophysical techniques and molecular simulations 

G. Widmalm (Stockholm) Stockholm University 

Chairs: A. Bernardi (Milano), I. Tvaroska (Bratislava) 

11:30-12:00 Room 3: Hidalgo 

Session 36. 

INV. 42. Inhibitors and activity-based probes to study glucosylceramide 

metabolism in man 

H. Overkleef (Leiden) , Leiden University, Leiden Institute of Chemistry 

Chairs: J. Paulson (La Jolla), M. von Iztstein (Queensland) 




O125 

CHEMICAL SYNTHESIS OF THE GLYCOPEPTIDE NHAc[βGAL-(1,3)αGALNAc]- 

THR3-[αLACNAc]-THR3-GLY-OVA RELATED TO T. CRUZI 

AND TUMOR MUCINS 

Leiria Campo, Vanessa; Dias-Baruffi , Marcelo; Carvalho, Ivone 

University of São Paulo, BRAZIL 

O126 

CONVERGENT SOLID PHASE SYNTHESIS OF SAPOSIN D 1-35 

GLYCOPEPTIDE THIOESTER EQUIVALENTS 

Schmälzlein, Marina 1 ; Heinlein, Christian 2 ; Unverzagt, Carlo 1 

1 University of Bayreuth, GERMANY 

2 Roche Diagnostics GmbH, Mannheim, GERMANY 

73 



74 

O127 

MODIFIED HIGH-MANNOSE GLYCO-CRAMBIN AS STABLE MIS-FOLDED 

GLYCOPROTEIN PROBES FOR A STUDY OF ER FOLDING SENSOR UGGT 

IN A “LIVE VIEW” METHOD 

Dedola, Simone 1,2 ; Makimura, Yutaka1,2 ; Izumi, Masayuki 1,2 ; Seko, Akira 1 ; Ito, 

Yukishige 1,3 ; Kajihara, Yasuhiro 1,2 

1 Japan Science and Technology Agency, JAPAN 

2 Osaka University Depatment of Chemistry Graduate School of Science, 

JAPAN+ 



Session 34. Structural Glycobiology and Molecular Recognition 

ORAL 

O128 

SYNTHESIS OF NON-NATURAL OLIGOSACCHARIDES BY 

PHOSPHORYLASE-CATALYZED ENZYMATIC GLYCOSYLATIONS 

Kadokawa, Jun-Ichi; Takemoto, Yasutaka; Yamamoto, Kazuya 

Graduate School of Science and Engineering, Kagoshima University, JAPAN 

O129 

STRUCTURAL AND KINETIC ANALYSIS OF ENDO-ALPHA-MANNOSIDASE 

Thompson, Andrew 1 ; Williams, Rohan 2 ; Hakki, Zalihe 2 ; Williams, Spencer 2 ; 

Davies, Gideon 1 

1 Department of Chemistry, University of York, UNITED KINGDOM 

2 School of Chemistry and Bio21 Institute, University of Melbourne, AUSTRALIA 

O130 

PURIFICATION AND CHARACTERIZATION OF EXO-POLYSACCHARIDES 

WITH COMPLEMENT FIXING AND MACROPHAGE STIMULATING 

ACTIVITY FROM SUBMERGED CULTIVATION OF THE MUSHROOM 

Hypsizigus marmoreus 

Paulsen, Berit Smestad 1 ; Zhang, Bing-Zhao 1,2 ; Inngjerdingen, Kari Tvete 1 ; 

Zou, Yuan-Feng 1 ; Vestrheim, Anne Cathrine 1,3 ; Michaelsen, Terje Einar 1,3 ; 

Yan, Pei-Sheng 2,4 

1 University of Oslo, NORWAY 

2 Harbin Institute of Technology, Harbin, CHINA 

3 The Norwegian Institute of Public Health, NORWAY 

4 Harbin Institute of Technology at Weihai, CHINA 

Madrid, Spain

12.00-12.45 Room 4: Doblón 

July 22-27, 2012. 

Session 35. Immunity 

ORAL 

O131 

PEPTIDOGLYCAN AS NOD1 LIGAND; FRAGMENT STRUCTURES IN 

THE ENVIRONMENT, CHEMICAL SYNTHESIS, AND THEIR INNATE 

IMMUNOSTIMULATION 

Fujimoto, Yukari 1 ; Pradipta, Ambara 1 ; Hasegawa, Mizuho 2 ; Inohara, Naohiro 2 ; 

Fukase, Koichi 1 

1 Osaka University, JAPAN 

2 The University of Michigan Medical School, USA 

O132 

DIVERSELY FUNCTIONALIZED 3,4,5-TRIHYDROXYPIPERIDINES FROM A 

D-LYXARIC ALDEHYDE 

Cardona, Francesca; Matassini, Camilla; Goti, Andrea 

Department of Chemistry, University of Florence, ITALY 

O133 

α-L-RHAMNOSIDASE FROM A. TERREUS IN SELECTIVE TRIMMING OF 

FLAVONOID GLYCOSIDES 

Kren, Vladimir; Gersdorferova, Daniela; Weignerova, Lenka; Fliederova, 

Barbora; Adamcova, Katerina; Marhol, Petr 

Institute of Microbiology, Academy of Sciences, CZECH REPUBLIC 

12.00-12.45 Room 3: Hidalgo 

Session 36. Chemical Glycobiology 

ORAL 

O134 

STRUCTURE-BASED ENGINEERING OF GLYCOENZYMES FOR THE 

DEVELOPMENT OF CHEMO-ENZYMATIC PATHWAYS TO ACCESS 

BACTERIAL CARBOHYDRATES 

André, Isabelle 1 ; Cambon, Emmanuelle 1 ; Guérin, Frédéric 1 ; 

Champion, Elise 1 ; Vergès, Alizée 1 ; Barbe, Sophie 1 ; Moulis, Claire 1 ; Salamone, 

Stéphane 2 ; Mulard, Laurence A. 2 ; Remaud-Siméon, Magali 1 

1 Laboratoire D’Ingénierie Des Systèmes Biologiques Et Des Procédés-INSA, 

UMR CNRS 5504, INRA 792; Université de Toulouse, FRANCE 

2 Institut Pasteur, Unité de Chimie des Biomolécules, FRANCE 

75 



76 

O135 

STRUCTURAL MECHANISM OF GLYCONE SELECTION IN PLANT BETA- 

D-MANNOSIDASES/BETA-D-GLUCOSIDASES 

Tankrathok, Anupong. 1 ; Ketudat Cairns, James R 1 ; Williams, Spencer J. 2 ; 

Prasert, Por-ngam 1 ; Pengthasong, Salila 1 ; Luang, Sukanya 1 ; Hrmova, Maria 3 ; 

Kuntothom, Teerachai 4 ; Robinson, Robert C. 5 ; Kimura, Atsuo 6 

1 Suranaree University of Technology, Institute of Science, THAILAND 

2 University of Melbourne, School of Chemistry & Bio21 Molecular Science & 

Biotechnology Inst., AUSTRALIA 

3 University of Adelaide, Centre for Plant Functional Genomics, AUSTRALIA 

4 Mahasarakham University, Faculty of Science, Dept. of Chemistry, THAILAND 

5 Institute of Cell and Molecular Biology, A*Star, SINGAPORE 

6 Hokkaido University, Graduate Faculty of Agriculture, JAPAN 

O136 

RATIONAL DESIGN OF GLYCOMIMETIC INHIBITORS OF 

GLYCOSYLTRANSFERASES 

Marca, Eduardo 1 ; Gomollon-Bel, Fernando 1 ; Delso, Ignacio 2 ; Tejero, Tomás 1 ; 

Hurtado-Guerrero, Ramón 3 ; Merino, Pedro 1 

1 Instituto de Síntesis Quimica y Catálisis Homogénea (ISQCH), Universidad de 

Zaragoza-CSIC, SPAIN 

2 Servicio de RMN, CEQMA, Universidad de Zaragoza-CSIC, SPAIN 

3 Instituto de Biocomputación y FÍsica de Sistemas Complejos (BIFI), 

Universidad de Zaragoza, SPAIN 


Session 33. 

INV. 34. Synthesis of Glycoproteins from Scratch: A puzzle of synthetic 

challenges 

C. Unverzagt (Bayreuth), Universitaet Bayreuth 



Session 34. 

INV. 37. Synthetic glycoconjugates: A tool for exploring and exploiting the 

molecular recognition in medicine 

V. Vérez Bencomo (La Habana), Centro De Quimica Biomolecular 

Chairs: M. Sollogoub (`Paris), J. I. Karokawa (Kagoshima) 

12:45-13:15 Room 4: Doblón 

Session 35. 

INV. 40. Some contributions of molecular modeling to carbohydrate 

chemistry 

C. Stortz (Buenos Aires),Universidad de Buenos Aires 


Madrid, Spain

12:45-13:15 Room 3: Hidalgo 

Session 36. 

INV. 41. Modulation of starch digestion for slow glucose release through 

“toggling” of activities of mucosal a-glucosidases 

B. M. Pinto (Burnaby), Simon Fraser University 

July 22-27, 2012. 

Chairs: J. Paulson (La Jolla), M. von Iztstein (Queensland 


Session 33. 

INV. 35. Glycan remodeling on glycoproteins: NMR investigations of 

structure and dynamics 

J. H. Prestegard (Georgia), University Of Georgia, CCRC 



Session 34. 

INV. 38. Viruses and Sialic Acid Receptor: Rules of Engagement 

T. Stehle (Tuebingen), University Of Tuebingen 

Chairs: M. Sollogoub (Paris), J. I. Kadokawa (Kagoshima) 

13:15-13:45 Room 4: Doblón 

Session 35. 

INV. 41. How strong and important are dispersion interactions for 

carbohydrate binding to proteins 

J. Koca (Brno), Central European Inst of Technology, Masaryk University 


13:15-13:45 Room 3: Hidalgo 

Session 36. 

INV. 44. Glycolipid biosynthesis by glycosyltransferases in Mollicutes. 

Potential targets against mycoplasma infections 

A. Planas (Barcelona), Institut Químic De Sarrià, Universitat Rmon Llull 

13.45-15-15 LUNCH 

Chairs: J. Paulson (La Jolla), M.von Iztstein (Queensland) 


Session 37. 

INV. 45. Glyco-inspired compounds in medicinal chemistry: drugs, 

scaffolds and tools 

B. La Ferla (Milano), University Of Milano-Bicocca 

Chairs: P. Fügedi (Budapest), L. Szente (Budapest) 

77 




Session 39. 

INV. 49. Glycomimetic antagonists of the C-lectin DC-SIGN 

A. Bernardi (Milano), Universita’ Di Milano 

78 

Chairs: X. S. Ye (Beijing), Isabelle André (Toulouse) 

15:15-15:45 Room 3: Hidalgo 

Session 41. 

INV. 52. Design of allosteric inhibitors of galectin-1 carbohydrate binding 

K. H. Mayo (Minneapolis-Minnesota), University Of Minnesota 

Chairs: J. Angulo (Sevilla), J. H. Prestegard (Georgia) 

15:15-15:45 Room 4: Doblón 

Session 43. 

INV. 56. Endohexosaminidase Catalysed Synthesis of Glycopeptides and 

Proteins 

A. Fairbanks (Christchurch), University Of Canterbury 

Chairs: J. C. Morales (Sevilla), F. Santoyo (Granada) 



FLASH 

F141 

THE EXPERIENCE WITH THE MICHAELIS-ARBUZOV REACTION 

Moravcová, Jitka; Jambal, Irekhjargal; Kefurt, Karel; Hlaváèková, Martina 

Institute of Chemical Technology, Prague, CZECH REPUBLIC 

F142 

SYNTHESIS OF GLYCOSIDASE INHIBITORS VIA FREE RADICAL 

CYCLISATION REACTIONS: NEW SYNTHETIC APPROACHES TO 

IMINOSUGARS AND THIOSUGARS 

Malone, Aoife; Scanlan, Eoin 

Trinity College Dublin, IRELAND 

F143 

COMPLEMENTARY PATHWAYS TO UNPROTECTED β-GLYCOSYL AZIDES 

Boos, Irene; Niemietz, Mathäus; Unverzagt, Carlo 

University of Bayreuth, GERMANY 

Madrid, Spain

July 22-27, 2012. 

F144 

REGIOSELECTIVE POLYMETHYLATION OF ALPHA-(1 → 4)-LINKED 

MANNOPYRANOSE OLIGOSACCHARIDES 

Xia, Li 

Alberta Glycomics Centre and Department of Chemistry, CANADA 

F145 

ONGOING STUDIES ON SUGAR-DERIVED γ-AMINO ACIDS. 

PART 1: 2-(2-AMINOCYCLOHEXYL)ALKANOIC ACIDS AND THEIR 

PEPTIDES 

González-Castro, M.A.; Estévez, A.M.; Sussman, F.; Estévez, J.C.; Estévez, 

R.J. 

Center For Research in Chemical Biology and Molecular Materials (CIQUS) 

Glycochemistry Laboratory, Universidade de Santiago de Compostela, SPAIN 



FLASH 

F147 

CHEMO-ENZYMATIC SYNTHESIS OF LIPO-CHITINOLIGOSACCHARIDE 

(LCOs) ANALOGS WITH A CELLODEXTRIN BACKBONE 

Fort, Sebastien 1 ; Claisse, Nathalie1 ; Vidal, Serge 2 

1 CERMAV, FRANCE 

2 ERAS Labo, FRANCE 

F148 

CLICK-ASSISTED SHORT SYNTHESES OF DIMERIC AND SELF- 

ASSEMBLING CYCOLDEXTRINS ENABLE MANY APPLICATIONS 

Adam de Beaumais, Ségolène; Menand, Mickaël; Sollogoub, Matthieu 

Upmc-Ipcm, FRANCE 

F149 

CELLULOSE NANO-PARTICLES COVERED WITH POLY(METHYL 

METHACRYLATE) CHAINS OF BLOCK COPOLYMER OF CELLULOSE 

AND METHYL METHACRYLATE PRODUCED BY MECHANO CHEMICAL 

POLYMERIZATION 

Sakaguchi, Masato 1 ; Ohura, Takeshi 2 ; Iwata, Tadahisa 3 ; Enomoto-Rogers, 

Yukiko 3 

1 Institute For Environmental Sciences, University of Shizuoka, JAPAN 

2 Faculty of Agriculture, Meijo University, JAPAN 

3 Department of Biomaterial Sciences, Graduate School of Agricultural and Life 

Sciences, The University of Tokyo, JAPAN 

F150 

THE FIRST TOTAL SYNTHESIS OF GANGLIOSIDE HPG-7 

Iwayama, Yuki 1,2 ; Ando, Hiromune 1,2 ; Ishida, Hideharu 1 ; Kiso, Makoto 1,2 

1 Department of Applied Bioorganic Chemistry, Gifu University, JAPAN 

2 iCeMS, Kyoto University, JAPAN 

79 



80 

F151 

CYCLODEXTRIN BASED CORKS AS NOVEL ANTIMICROBIAL 

THERAPEUTICS 

Jicsinszky, Laszlo 1,2 ; Robinson, Tanisha 1 ; Tuza, Kata 2 ; Karginov, Vladimir 1 

1 Innovative Biologics Inc, USA 

2 Cyclolab R&D Lab. Ltd., Budapest, HUNGARY 

15.45-16.10 Room 3: Hidalgo 

Session 41. Synthesis and Glycomaterials 

FLASH 

F156 

SYNTHESIS OF A NOVEL FULL POLYSACCHARIDE-BASED DRUG 

DELIVERY SYSTEM 

Sadeghi, Mohammad 

Islamic Azad University Of Arak, IRAN 

F157 

SYNTHESIS OF RHAMNOGALACTURONAN I OLIGOSACCHARIDES 

Zakharova, Alexandra; Madsen, Robert; Clausen, Mads 

Technical University of Denmark, DENMARK 

F158 

SYNTHESIS AND BIOLOGICAL EVALUATION OF GLYCOSYLATED 

PORPHYRINS AS PHOTODYNAMIC THERAPY AGENTS 

Daly, Robin 1 ; Vaz, Gisella 2 ; Davies, Anthony 2 ; Senge, Mattias 1,2 ; 

Scanlan, Eoin 1 

1 School of Chemistry, Trinity Biomedical Sciences Institute, University of 

Dublin, Trinity College, Dublin, IRELAND 

2 Institute of Molecular Medicine, Medicinal Chemistry, Trinity Centre for Health 

Sciences, St. James’s Hospital, Dublin, IRELAND 

F159 

USE OF JELLYFISH MUCIN (QNIUMUCIN) AS A BIODEGRADABLE 

ION-EXCHANGE POLYMER 

Ushida, Kiminori 

School of Science, Kitasato University, JAPAN 

F160 

PYRANOSIDE CONFORMATIONAL EFFECT ON REACTIVITY AND 

SELECTIVITY IN GLYCOSYLATION REACTIONS 

Manabe, Shino 1 ; Ishii, Kazuyuki1,2 ; Satoh, Hiroko 3 ; Hashizume, Daisuke 1 ; Ito, 

Yukishige 1,4 


2 PRESTO, JST, JAPAN 

3 National Institute of Informatics (NII), JAPAN 

4 ERATO, JST, JAPAN 

Madrid, Spain

15.45-16.10 Room 4: Doblón 

July 22-27, 2012. 

Session 43. Synthesis & Glycomaterials 

FLASH 

F165 

CONFORMATION AND PHYSICAL PROPERTIES OF LINEAR AND CYCLIC 

ISOMALTOOLIGOSACCHARIDES IN AQUEOUS SOLUTION 

Suzuki, Shiho 1 ; Yukiyama, Takashi 1 ; Ishikawa, Arata 1 ; Yuguchi, Yoshiaki 2 ; 

Funane, Kazumi 3 ; Kitamura, Shinichi 1 

1 Osaka Prefecture University, JAPAN 

2 Osaka Electro-Communication University, JAPAN 

3 National Agriculture and Food Research Organization, JAPAN 

F166 

EFFECT OF PLASTICIZER CONTENT ON ANTIOXIDANT ACTIVITY OF 

CHITOSAN-BASED FILMS 

Nunes, Cláudia; Cunha, Ângela; Coimbra, Manuel A.; Lopes da Silva, José A. 

Universidade de Aveiro, PORTUGAL 

F167 

ENZYMATIC DEGRADATION OF UNMODIFIED CHITOSAN AND DERIVATES 

THEREOF 

Laffl eur, Flavia; Hintzen, Fabian; Shahnaz, Gul; Bernkop-Schnürch, Andreas 

University of Innsbruck, AUSTRIA 

F168 

ENANTIOSPECIFIC SYNTHESIS OF SPIROACETALS FROM ALDOSES VIA 

TANDEM ALDOL REACTION 

Machinami, Tomoya 1 ; Miura, Daisuke1 ; Kano, Ryou 1 ; Tsutsui, Ayumi 2 ; Fujimoto, 

Takashi 1 

1 Meisei University, JAPAN 

2 Kitasato University, JAPAN. 

F169 

SYNTHESIS OF HETERO-GLYCOCLUSTERS AS NEW PLATFORMS FOR 

THE CONSTRUCTION OF ANTICANCER VACCINE CANDIDATES 

Fiore, Michele; Thomas, Baptiste; Dumy, Pascal ; Renaudet, Olivier 

Département de Chimie Moléculaire, UMR-CNRS 5250 & ICMG FR 2607, 

Université Joseph Fourier, Grenoble, FRANCE 


Session 37 

INV. 46. The Cycloddition Way to Glycosidic Immunostimulants 

C. Nativi (Florence) University Of Florence 

Chairs: P. Fügedi (Budapest), L. Szente (Budapest) 

81 




Session 39. 

INV. 50. Linear and cyclic oligo-ß-(1?6)-D-glucosamines: synthesis, 

conformations and application for vaccine and oligodentate conjugates 

design 

N. Nifantiev (Moscow) N.D. Zelinsky Institute Of Organic Chemistry, Russian 

Academy Of Sciences 

Chairs: X. S. Ye (Beijing), Isabelle André (Toulouse) 

16:40-17:00 Room 3: Hidalgo 

Session 41. 

INV. 53. Structural views of carbohydrate-protein interaction systems as 

potential therapeutic targets 

K. Kato (Okazaki) National Institutes of Natural Sciences 

Chairs: J. Angulo (Sevilla), J. H. Prestegard (Georgia) 

16:40-17:00 Room 4: Doblón 

Session 43. 

INV. 57. Chemo-enzymatic synthesis of asymmetrically substituted multiantennary 

glycans for microarray development 

G. J. Boons (Georgia), University of Georgia, Complex Carbohydrate Research 

Center 

Chairs: J. C. Morales (Sevilla), F. Santoyo (Granada) 



ORAL & FLASH 

82 

O137 

TEMPO-MEDIATED CONJUGATION AFFORDS GLYCOCONJUGATE 

VACCINES WITH IMPROVED STRUCTURAL INTEGRITY AND 

IMMUNOGENICITY 

Monteiro, Mario 

University of Guelph, CANADA 

F146 

TARGETING BACTERIAL MEMBRANES BY AMPHIPHILIC AMINOSUGAR 

ANALOGUES 

Fridman, Micha; Herzog, Ido M.; Feldman, Mark; Berkov-Zrihen, Yifat 

Tel-Aviv University, ISRAEL 

Madrid, Spain



FLASH 

F152 

NMR ANALYSIS OF SIGLEC-7 CARBOHYDRATE RECOGNITION 

Pröpster, J.M.; Landig, C.; Vögeli, B.; Allain, F.H.T.; Schubert, M. 

Institute of Molecular Biology and Biophysics, ETH Zürich, Zürich, 

SWITZERLAND 

F153 

ORTHOGONALLY PROTECTED D-GLUCOSAMINE AND 

D-GALACTOSAMINE BUILDING BLOCKS FOR THE SYNTHESIS OF 

MUCIN TYPE OLIGOSACCHARIDES 

Kulkarni, Suvarn; Emmadi, Madhu 

Indian Institute of Technology Bombay, INDIA 

F154 

IMINOSUGAR-BASED INHIBITORS OF INSECT TREHALASE 

Bini, Davide 1 ; Sgambato, Antonella 1 ; Forcella, Matilde 1 ; Cardona, Francesca 2 ; 

Matassini, Camilla 2 ; Fusi, Paola 1 ; Parenti, Paolo 3 ; Cipolla, Laura 1 

1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, 

July 22-27, 2012. 

ITALY 

2 Department of Chemistry, University of Florence, ITALY 

3 Department of Environmental Sciences, University of Milano-Bicocca, ITALY 

16.40-17.00 Room 3: Hidalgo 

Session 41. Synthesis & Glycomaterials 

FLASH 

F161 

ENDO/EXO C-O BOND CLEAVAGE MANNERS OF GLYCOSIDES WITH 

2,3-TRANS OR 2,3-CIS CYCLIC PROTECTING GROUPS 

Satoh, Hiroko 1 ; Manabe, Shino 2 ; Ito, Yukishige 2 ; Luethi, Hans Peter 3 ; Laino, 

Teodoro 4 ; Hutter, Juerg 5 

1 National Institute of Informatics, JAPAN 


3 Swiss Federal Institute of Technology (ETH), SWITZERLAND 

4 IBM Research Zurich, SWITZERLAND 

5 University of Zurich, SWITZERLAND 

F162 

ENZYMATIC SYNTHESIS OF POLY-N-ACETYLLACTOSAMINE (pLN) N- 

and O-glycans FOR GALECTIN RECOGNITION 

Peng, Wenjie 1 ; McBride, Ryan 1 ; Pranskevich, Jennifer 1 ; 

Rangarajan, Janani 1 ; Nycholat, Corwin 1 ; Gilbert, Michel 2 ; 

Wakarchuk, Warren 2 ; Razi, Nahid 1 ; Paulson, James 1 

1 The Scripps Research Institute, La Jolla, USA 

2 National Research Council of Canada, CANADA 

83 



84 

F163 

ARRAYS OF PEGylated GLYCANS PREPARED BY ENZYMATIC SOLID- 

PHASE SYNTHESIS 

Echevarria, Juan; Serna, Sonia; Martín-Lomas, Manuel; Reichardt, Niels 

Christian 

CIC BiomaGUNE, SPAIN 

F164 

IN VITRO AND IN VIVO RELEASE BEHAVIOR OF THEOPHYLLINE FROM 

SOME POLYMERIC CARRIERS BASED HYDROGELS 

Novac, Ovidiu 1 ; Cheaburu, Catalina Elena 2 ; Vasile, Cornelia 2 ; Lupusoru, 

Catalina Elena 3 ; Popa, Ionel Marcel 1 

1 Technical University ‘Gh. Asachi’, Faculty of Chemical Engineering and 

Environmental Protection, Iasi, ROMANIA 

2 Institute of Macromolecular Chemistry ‘Petru Poni’, Iasi, ROMANIA 

3 University of Medicine and Pharmacy ‘Gr. T. Popa’, Iasi, ROMANIA 

16.40-17.00 Room 4: Doblón 

Session 43. Synthesis Glycomaterials 

FLASH 

F170 

SYNTHESIS AND CHARACTERIZATION OF CARBOHYDRATE GRAFTED 

COPOLYMERS FOR HEAVY METALS, ANIONIC DYE REMOVALS AND 

FLOCCULATION 

Tera, Ferial 1 ; Elalfy, Ekhlas2 ; Nasr, Hanaa 2 ; Hussein, Samaha 1 

1 National Institute For Standards, EGYPT 

2 National Research Centre 

F171 

ORAL DELIVERY OF ACETAMINOPHEN USING NATURAL BASED 

SUPERABSORBENT HYDROGEL 

Soleimani, Fatemeh 1 

1 Islamic Azad University of Khorramabad, IRAN 

2 Young researchers club, Islamic Azad University, Khorramabad Branch, 

Khorramabad, IRAN 


Session 38 

INV. 47. The Challenge of Working With Sugars: New Agents Against 

Infectious or Degenerative Diseases 

A. P. Rauter (Lisboa), University of Lisbon 

Chairs: A. Siriwardena (Amiens), O. Holst (Borstel) 

Madrid, Spain


Session 40 Glycobiology 

ORAL & FLASH 

July 22-27, 2012. 

O138 

ARABINOFURANOSIDASE 51 AS BIOCATALYSTS: FROM THE DESIGN 

OF MUTANTS TO INNOVATIVE APPLICATIONS 

Daniellou, Richard 1 ; Ferrieres, Vincent 2 ; Lafi te, Pierre 1 ; Nugier-Chauvin, 

Caroline 2 

1 ICOA, University of Orléans, UMR CNRS 7311, FRANCE 

2 ENSCR-UMR CNRS 6226, FRANCE 

F155 

STEREOSELECTIVE SYNTHESIS OF A TETRAANTENNARY CORE- 

FUCOSYLATED N-GLYCAN AZIDE 

Niemietz, Mathäus 1 ; Eller, Steffen 2 ; Luber, Thomas 1 ; Unverzagt, Carlo 1 

1 University of Bayreuth, GERMANY 

2 Max Planck Institute of Colloids and Interfaces, Department of Biomolecular 

Systems, Free University, Department of Chemistry, Berlin, GERMANY 

17:00-17:30 Room 3: Hidalgo 

Session 42. 

INV. 54. Furanoside Biosynthesis in Mycobacteria and Campylobacters 

T. Lowary (Alberta), The University Of Alberta, Department Of Chemistry 

17:00-17:30 Room 4: Doblón 

Chairs: R. Woods (Galway), B. Grindley (Halifax) 

Session 44. 

INV. 58. Structural Basis for Broad Substrate Specifi city of Hydrolytic 

Enzymes that Modify Plant Cell Walls 

M. Hrmova (Glen Osmond), The University Of Adelaide 

Chairs: T. Velasco-Torrijos (Maynooth), A. Nikolaev (Dundee) 


Session 38. 

INV. 48. Using glycodendrimers for studies of antimicrobial and cancer 

cell processes 

M. J. Cloninger (Bozeman, Montana), Montana State University 

Chairs: A. Siriwardena (Amiens), O. Holst (Borstel) 

85 



86 

Session 40. 

INV. 51. Chemical Biology of Carbohydrates: Multivalent Interactions and 

Metabolic Oligosaccharide Engineering 

V. Wittmann (Konstanz), University Of Konstanz 

17:30-18:00 Room 3: Hidalgo 

Chair: M.Wimmerova (Brno), G. van der Marel (Leiden) 

Session 42. 

INV. 55. Glycotransporters for Gene Delivery 

J. M. García Fernández (Sevilla), Institute For Chemical Research, CSIC- 

University Of Sevilla 

17:30-18:00 Room 4: Doblón 

18:00-18:30 Conclusions 

Chairs: R. Woods (Galway), B. Grindley (Halifax) 

Session 44. 

INV. 59. Mechanistic studies and application in synthesis of a plant 

C-glycosyltransferase 

B. Nidetzky (Graz), Graz University of Technology, Institute of Biotechnology 

and Biochemical Engine 

Chairs: T. Velasco-Torrijos (Maynooth), A. Nikolaev (Dundee) 

Madrid, Spain

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