4. Quarter - Rabies - Bulletin - Europe

Volume 36 • No 4 • 2012WHORABIES BULLETINEUROPEISSN 0257-8506WHO Collaborating Centre for Rabies Surveillance and Research

3 Miscellaneous Articles3.1 A One Health Model for elimination of canine-mediated humanrabies in Bohol PhilippinesStella Marie Lapiz 1 , Mary Elizabeth G Miranda 2 , Romulo G Garcia 1 , Leonida I Dauro 1 , Meydalyn DPaman 1 , Frederick P Madrinan 1 , Polizena A Rances 3 , Deborah J Briggs 21 Office of the Provincial Veterinarian, Capitol Annex, Tagbilaran City, Philippines2 Global Alliance for Rabies Control, Humboldt St. Suite One, Manhattan, Kansas USA3 Provincial Health Office, Capitol Annex, Tagbilaran City, PhilippinesThis brief article summarizes the recently published manuscript describing a successful One Healthapproach to tackling canine-mediated human rabies. The complete article can be downloaded from:http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001891).INTRODUCTIONA One Health rabies elimination andcontrol project was conducted onBohol Island, Philippines between2007-2010. Bohol is an islandprovince with a population of 1.3million inhabitants located in theVisayas region of the Philippines andis surrounded by canine-rabiesendemic regions with frequent boattraffic travelling to nearby rabiesendemic islands. Prior to theinitiation of the Bohol RabiesPrevention and Elimination Project(BRPEP), Bohol recorded an averageof 10 human rabies deaths per yearand ranked 4th highest province forhuman rabies fatalities in thecountry. The aim of the Boholproject was to develop a sustainableprogramme that would eliminate theprincipal source of human infection,i.e. rabies in unvaccinated dogs,and to improve surveillanceactivities in order to provide earlydetection of infected dogs that mayhave been transported back into theprovince.The BRPEP integrated expertisefrom several sectors within theprovince of Bohol that were requiredto successfully establish theprogramme including: agriculture;public health and safety; education;environment; legal affairs; as well5/27as interior and local government.Activities of the BRPEP includedincreasing local communityinvolvement; improving dogpopulation control; promotingresponsible pet ownership;implementing mass dog vaccination;improving dog bite management forhuman patients; initiatingveterinary quarantine for suspectrabid animals that exposed humans;and instituting a risk managementsystem that included improveddiagnostic capacity, diseasesurveillance and monitoring.Partnerships were established tosecure the required funding andincluded financial support from thenational, provincial and localgovernmental units of thePhilippines, dog owners, NGOs,regional office of the WHO, UBSOptimus Foundation, and the GlobalAlliance for Rabies Control. Themanagement of the BRPEP wasunder the direction of the Governorof Bohol. In order to maintainconsistency, parallel organizationsconsistent with the provincial BRPEPwere established at the municipaland village level.PROGRAMME COMPONENTSThe BRPEP was built on the existingnational regulation framework forrabies control and animal welfare

identified as the Anti-Rabies Act of2007. Additionally, the Governor ofBohol passed the ProvincialOrdinance No 2007-012 tostrengthen provincial adherence tothe national rabies control initiativeby establishing implementationbodies at the provincial, municipaland village levels.All communication for public healthactivities associated with the BRPEPwas coordinated through theprovincial government and a specifichandbook detailing the programmestrategy was developed anddistributed to maintain consistencyacross all levels of implementation.A Knowledge, Attitudes andPractices (KAP) survey wasconducted to evaluate change inawareness among 300 householdson Bohol. Because children wereespecially unaware of rabies andhow to prevent infection, a schoolbasededucational programme wascreated and implemented with closecooperation with the Department ofEducation. Teachers and educationalprofessionals were involved indeveloping specific curricula utilizingrabies prevention as a model forfive different subjects, i.e Math,Science, English, Filipino and SocialScience.In August of 2007, a mass dogvaccination programme wasinitiated by the Governor of Boholand led by Provincial VeterinaryOffice. Teams responsible for dogvaccination were organized at theprovincial and municipal levels.Mop-up dog vaccination campaignswere also conducted in areas wherethe initial coverage was less thanadequate. Dog population andmovement control was implementedin compliance with the NationalRabies Programme and AnimalWelfare Act.Figure 1: Map showing the Phillipines and the Bohol island (indicated by black arrow)6/27

In order to improve patient accessto PEP, 4 new Animal BiteTreatment Centers (ABTC) wereestablished, in addition to the twoexisting ABTCs, on Bohol. Trainingfor administration of PEP for medicalprofessionals was conducted underthe auspices of the national rabiesreferral center of the Department ofHealth located in the ResearchInstitute for Tropical Medicine,Metro Manila.To improve surveillance, animalsinvolved in potential humanexposures were observed for 14days. In the event that the animaldeveloped clinical signs of rabies, itwas euthanized and submitted fortesting at the Regional AnimalDisease Diagnostic Laboratory inCebu, on the adjacent islandprovince. Training on the DirectRapid Immunohistochemical Test(dRIT) to enable improved diagnosison Bohol was conducted by anexpert from the US Centers forDisease Control and PreventionRabies Unit.RESULT OF THE PROGRAMMEThe BRPEP successfully reduced theburden of human rabies andbetween 2008 – 2010, with thenumber of human deaths reducedfrom approximately 10 per year to0. One suspect human case wasreported in November 2010 and onecanine case was confirmed in April2011. The fact that Bohol remainssurrounded by rabies endemicislands provides continuousopportunities for the importation ofinfected dogs. Improvedsurveillance activities along portsand other official channels of entryhave enabled the government tomonitor animals legally enteringBohol but clearly, there areopportunities for dogs to enterunofficially via small fishing boats.Therefore, the office of theprovincial veterinarian continues toremain vigilant in investigating anysuspect cases. The improvedsurveillance has permitted themobilization of ‘mop-up’ vaccinationcampaigns when required and haseffectively prevented rabies fromspreading back across the island.The total cost of the 3-year projectwas $450,000 US funded throughthe government, major donors andNGOs. Additional funding to ensuresustainability has been realizedthrough a small dog registration fee.For around $1 per dog, the dogreceives a registration card,vaccination against rabies and acollar and dog tag. In the event of abite injury by a registered andvaccinated dog, the post-exposureprophylaxis is subsidized by theGovernment according to theprovincial ordinance. Theseincentives and a strong communityinvolvement programme withemphasis on responsible petownership has ensured that dogregistration rates are high and thecommunity has taken ownership ofthis programme. Income from dogowners’ registration fees continuesto help financially maintain theprogramme as all funds raisedthrough the fees are delivered backinto the BRPEP to supportcommunity based activities.Programme sustainability has beenapproached through a variety ofactivities focusing on advocacy,public awareness, child education,legislation and dog registration.Most importantly, sustainability isalso maintained by improvedcommunity involvement includinglocal volunteers. The number ofcitizens involved in rabiesprevention and control across theisland of Bohol has increased from140 prior to the initiation of theprogramme to over 15,000 at thepresent time. In 2011, the BRPEPwas awarded the prestigious Galing7/27

Pook Award for its achievement bythe Honorable Benigno Aquino III,the President of the Philippines. TheBRPEP continues to serve as amodel for “One Health” and wasachieved through the joint efforts oflocal and national government ofthe Philippines, contributions fromdonors, and the dedicated efforts ofexperts from the sectors of publichealth, education, animal health andagriculture,environment,legislation, and non-governmentpartners.ACKNOWLEDGEMENTSWe thank all the provincial andmunicipal health, veterinary andagriculture workforce, the publicschool teachers andsuperintendents, provincial legaloffice staff, local media partners,local community volunteers andMembers of Bohol Rabies Preventionand Elimination Council whoprovided invaluable assistance withfield program implementation. TheUBS Optimus Foundation, the WHOOffice in Manila, IP Foundation andthe Gift of Life Foundationsupported the project with valuablematerial and technical support. Weare also grateful to National RabiesPrevention and Control Program, theDepartment of Health NationalCenter for Disease Prevention andControl, and the Bureau of AnimalIndustry. We thank Dr SusannaHausmann, Dr Ann-Marie Sevcsik,Mal Hoover, Sunny Townsend, MikeShand, Katie Hampson and TizianaLembo for helpful input. Kim Doyle,Louise Taylor and Peter Costa gavetheir constant and encouragingsupport throughout the projectimplementationREFERENCESQuiambao BP, Dimaano EM, Ambas C,Davis R, Banzhoff A, Malerczyk C.(2005). Reducing the cost of postexposureprophylaxis: efficacy of 0.1ml PCEC rabies vaccine administeredintradermally using the Thai RedCross post-exposure regimen inpatients severely exposed tolaboratory-confirmed rabid animals.Vaccine 23:1709-14.Philippine National Rabies Report (2009)Philippine National Government.Manila.World Health Organization (2005) WHOExpert Consultation on Rabies(2004). First Report. (WHOTechnicalReport Series 931) Geneva,Switzerland.Fishbein DB, Miranda NJ, Merrill P,Camba RA, Meltzer M, et al. (1991)Rabies control in the Republic of thePhilippines: benefits and costs ofelimination. Vaccine 9:581-87.Blueprint for rabies prevention andcontrol. Partners for RabiesPrevention.Available:www.rabiesblueprint.com. AccessedFebruary 2011.Provincial Planning and DevelopmentOffice, Provincial Development andPhysical Framework Plan 2010-2015.Available:http://www.ppdobohol.lgu.ph/.Accessed June 2011.Anti-Rabies Act of 2007. “An ActProviding for the Control andElimination of Human and AnimalRabies. Republic Act No. 9482.Government of the Philippines.Available:http://www.senate.gov.ph/lis/pdf_sys.aspx?congress=13&type=republic_act&p=1. Accessed June 2011.Bohol Rabies Prevention and EliminationHandbook (2007). Bohol ProvincialGovernment. Tagbilaran City, Bohol,Philippines.Robinson LE, Miranda ME, Miranda NL,Childs JE. (1996). Evaluation of acanine rabies vaccination campaignand characterization of owned dogpopulations in the Philippines.Southeast Asian J Trop Med Pub Hlth.27:2:250-56.Davlin S, Lapiz SM, Miranda ME, MurrayK. (in press) Factors associated withdog rabies vaccination in Bohol,Philippines: Results of a crosssectionalcluster survey conductedduring the island-wide rabieselimination campaign. Zoonoses andPublic Health.8/27

3.2 Announcement: 2nd edition of the book on Dogs, Zoonoses andPublic HealthThis 2nd edition provides an evenmore comprehensive account of thechanging world and our culturallyand individually diverserelationships with “man’s bestfriend”, the domestic dog. The sizeof the world dog population isunknown but is positively correlatedto that of the human population.Based on a number of observationsit could be as high as one-tenth ofthe world human populations, with700 million dogs. A majority ofthose dogs, particularly in parts ofAfrica, the Middle East, and LatinAmerica, are or are regarded asstrays.People’s attitudes regarding dogsvary greatly from being onlybeneficial to humans to being aserious public health nuisance. Asdogs are present and closelyassociated with humans and/or theiractivities in almost all places, mostpeople will have a strong standregarding their role and impact onhuman society.A number of studies havedemonstrated that the human-dogbond has a positive impact onhuman health, child development,and the quality of life. The use ofdogs as companion animals, andcompanion animal medicine, areincreasingly being recognized asimportant areas contributing to thebetterment of human health. Dogsmay permit people to live healthier,happier lives, and recent studieshave shown the benefits dogsimpart to many segments of thepopulation including children,elderly people, those isolated bystigmatizing diseases such as AIDS,and the handicapped.However, there are problems anddogs contribute to zoonotic9/27infections and they foul pavementsand public parks. They pose apublic health nuisance throughbites; harassment of pets, livestockand wildlife; their persistent barkingparticularly at night; scavengingfrom garbage sites; and theirinvolvement in traffic accidents.The positive and negative attributespolarize people’s opinions aboutdogs. Because of the strongopinions held on both sides it isdifficult to get a balanced view, butwhatever one’s opinion, dogs arenow an important part of our societyin every corner of the world.Appropriate solutions to the issues,adhering with international animalwelfare principles, need to befound: a number of solutions areprovided in different chapters in thisbook.The book aims to a give acomprehensive account of thecomplex public health aspects of therelationship between humans anddogs. As well as a chapter focusingon dogs and rabies, chapters on theDog-human relationship, TheBenefits of the Human-DogRelationship, Dog associatedproblems, Dog PopulationManagement, Zoonosis Prevention,Control and Elimination in Dogs andFertility Control in Dogs would all berelevant to those interested inrabies control. The book also aimsto examine how our interaction withdogs in different cultures and socioeconomicconditions facilities bothbeneficial and harmful processes,and how the zoonotic diseases witha high health burden especiallyrabies are currently beingcontrolled.

dogcatcattleequinegoatsheeppigstray dogothersubtotalfoxracoondogracoonwolfbadgermartenothermustelidesothercarnivoreswild boarroe deerred deerfallowdeerothersubtotalbatHuman casestotal4 Distribution of Rabies in Europe4.1 Country summaries of rabies cases, 4 th quarter 2012 01.10.12 - 31.12.12CountryDomestic animalsWildlifeNameCodeAlbania ALB * 0 0 0Austria AUT * 0 0 0Belarus BLR 6 16 25 1 1 7 56 68 25 2 2 97 153Belgium BEL * 0 0 0Bosnia - Hercegovina BIH 0 3 3 3Bulgaria BGR * 0 0 0Croatia HRV 0 20 1 21 21Cyprus CYP * 0 0 0Czech Republic CZH * 0 0 0Denmark DNK * 0 0 0Estonia EST * 0 0 0Finland FIN * 0 0 0France FRA 0 0 1 1Germany DEU 0 0 1 1Greece GRC 2 2 7 7 9Hungary HUN * 0 0 0Iceland ISL * 0 0 0Ireland IRE * 0 0 0Italy ITA * 0 0 0Kosovo XXK * 0 0 0Latvia LVA * 0 0 0Lithuania LTU * 0 0 0Luxembourg LUX * 0 0 0Macedonia MKD * 0 0 0Malta MLT * 0 0 0Moldova MDA 8 4 49 1 3 65 7 1 8 73Montenegro MNE * 0 0 0Norway NOR * 0 0 0Poland POL 4 8 7 1 20 94 1 4 1 100 1 121Portugal PRT * 0 0 0Romania ROU 12 8 18 3 7 48 96 1 2 99 147Russian Federation RUS 115 139 104 4 12 2 5 381 255 69 2 4 3 4 1 2 2 342 1 724Serbia SRB 1 1 5 5 6Slovak Republic SVK * 0 0 0Slovenia SVN 0 1 1 1Spain ESP 2 2 0 1 3Sweden SWE * 0 0 0Switzerland + Lichtenstein CHE * 0 0 0The Netherlands NED 0 0 3 3Turkey TUR 28 5 50 1 4 88 7 7 1 96Ukraine UKR 114 192 110 3 13 432 291 15 4 4 1 4 319 751United Kingdom UNK * 0 0 0TOTAL 291 373 363 13 41 2 12 0 1095 854 109 0 10 5 14 5 3 0 3 0 0 6 1009 7 2 2113PER CENT 13,8% 17,7% 17,2% 0,6% 1,9% 0,1% 0,6% 0,0% 51,8% 40,4% 5,2% 0,0% 0,5% 0,2% 0,7% 0,2% 0,1% 0,0% 0,1% 0,0% 0,0% 0,3% 47,8% 0,3% 0,1% 100%10/27

dogcatcattleequinegoatsheeppigstray dogothersubtotalfoxracoondogracoonwolfbadgermartenothermustelidesothercarnivoreswild boarroe deerred deerfallowdeerothersubtotalbatHuman casestotal4.2 Country summaries of rabies cases, 2012 totalCountryDomestic animalsWildlifeNameCodeAlbania ALB 2 2 0 2Austria AUT * 0 0 0Belarus BLR 71 65 46 4 4 1 14 205 235 48 3 3 1 1 1 9 301 1 1 508Belgium BEL * 0 0 0Bosnia - Hercegovina BIH 0 6 6 6Bulgaria BGR * 0 0 0Croatia HRV 5 3 12 1 21 140 1 2 2 145 166Cyprus CYP * 0 0 0Czech Republic CZH * 0 0 0Denmark DNK * 0 0 0Estonia EST * 0 0 0Finland FIN * 0 0 0France FRA 0 0 9 9Germany DEU 0 0 14 14Greece GRC 2 2 7 7 9Hungary HUN 0 0 1 1Iceland ISL * 0 0 0Ireland IRE * 0 0 0Italy ITA * 0 0 0Kosovo XXK * 0 0 0Latvia LVA 1 1 2 0 2Lithuania LTU 1 1 2 1 2 3 5Luxembourg LUX * 0 0 0Macedonia MKD 1 1 2 2 3Malta MLT * 0 0 0Moldova MDA 30 20 87 1 16 1 155 25 1 2 1 29 184Montenegro MNE 1 1 0 1Norway NOR * 0 0 0Poland POL 13 14 10 1 38 200 2 2 10 1 1 216 3 257Portugal PRT * 0 0 0Romania ROU 52 30 40 5 9 3 139 305 2 1 3 2 4 1 318 1 458Russian Federation RUS 301 356 184 6 21 2 23 893 784 148 8 5 8 9 5 1 3 6 26 1003 4 1900Serbia SRB 1 1 17 1 18 19Slovak Republic SVK * 0 0 0Slovenia SVN 0 3 3 3Spain ESP 5 5 0 2 7Sweden SWE * 0 0 0Switzerland + Lichtenstein CHE 0 0 1 1The Netherlands NED 1 1 0 16 17Turkey TUR 188 30 194 10 17 439 51 2 1 1 1 1 57 1 497Ukraine UKR 359 562 201 8 25 2 4 1161 737 28 2 11 8 32 2 1 13 834 1995United Kingdom UNK 0 0 1 1TOTAL 1030 1084 776 34 94 9 37 4 3068 2511 228 2 29 16 57 19 9 8 6 0 6 51 2942 46 9 6065PER CENT 17,0% 17,9% 12,8% 0,6% 1,5% 0,1% 0,6% 0,1% 50,6% 41,4% 3,8% 0,0% 0,5% 0,3% 0,9% 0,3% 0,1% 0,1% 0,1% 0,0% 0,1% 0,8% 48,5% 0,8% 0,1% 100%11/27

dogcatcattleequinegoatsheeppigstray dogothersubtotalfoxracoondogracoonwolfbadgermartenothermustelidesothercarnivoreswild boarroe deerred deerfallowdeerothersubtotalbatHuman casestotal4.3 Rabies cases per country and administrative units, 4 th quarter 2012 01.10.12 - 31.12.12LocationDomestic animalsWildlifeB O S N I A - H E R C E G O V I N ATuzlanski 0 3 3 3TOTAL 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 3PER CENT 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 100,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 100,0% 0,0% 0,0% 100%C R O A T I AKarlovacka 0 1 1 1Primorsko - Goranska 0 2 2 2Sibensko - Kninska 0 1 1 1Splitsko - Dalmatinska 0 1 1 1Varazdinska 0 3 3 3Zagreb 0 5 5 5Zagrebacka 0 8 8 8TOTAL 0 0 0 0 0 0 0 0 0 20 0 0 1 0 0 0 0 0 0 0 0 0 21 0 0 21PER CENT 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 95,2% 0,0% 0,0% 4,8% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 100,0% 0,0% 0,0% 100%G E R M A N YLichtenfels 0 0 1 1TOTAL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1PER CENT 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 100,0% 0,0% 100%F R A N C EAquitaine 0 0 1 1TOTAL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1PER CENT 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 100,0% 0,0% 100%G R E E C EKastoria 1 1 0 1Kilkis 0 4 4 4Kozani 0 1 1 1Pella 1 1 2 2 3TOTAL 2 0 0 0 0 0 0 0 2 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 9PER CENT 22,2% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 22,2% 77,8% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 77,8% 0,0% 0,0% 100%P O L A N DLubelskie 0 2 2 2Malopolskie 1 1 2 18 18 20Podkarpackie 4 7 7 18 74 1 4 1 80 98Pomorskie 0 0 1 1TOTAL 4 8 7 0 1 0 0 0 20 94 0 0 0 1 4 0 0 0 1 0 0 0 100 1 0 121PER CENT 3,3% 6,6% 5,8% 0,0% 0,8% 0,0% 0,0% 0,0% 16,5% 77,7% 0,0% 0,0% 0,0% 0,8% 3,3% 0,0% 0,0% 0,0% 0,8% 0,0% 0,0% 0,0% 82,6% 0,8% 0,0% 100%12/27

dogcatcattleequinegoatsheeppigstray dogothersubtotalfoxracoondogracoonwolfbadgermartenothermustelidesothercarnivoreswild boarroe deerred deerfallowdeerothersubtotalbatHuman casestotal4.3 Rabies cases per country and administrative units, 4 th quarter 2012 (continued) 01.10.12 - 31.12.12LocationDomestic animalsWildlifeB E L A R U SBrest 1 1 2 1 1 1 3 5Gomel 1 4 7 1 1 14 11 3 2 16 30Grodno 5 2 1 1 9 22 6 1 29 38Minsk 1 4 6 3 14 16 2 18 32Mogelev 3 1 1 5 14 3 17 22Vitebsk 1 1 8 2 12 4 10 14 26TOTAL 6 16 25 1 1 0 7 0 56 68 25 0 2 0 2 0 0 0 0 0 0 0 97 0 0 153PER CENT 3,9% 10,5% 16,3% 0,7% 0,7% 0,0% 4,6% 0,0% 36,6% 44,4% 16,3% 0,0% 1,3% 0,0% 1,3% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 63,4% 0,0% 0,0% 100%M O L D O V AMoldova 8 4 49 1 3 65 7 1 8 73TOTAL 8 4 49 1 3 0 0 0 65 7 0 0 0 0 1 0 0 0 0 0 0 0 8 0 0 73PER CENT 11,0% 5,5% 67,1% 1,4% 4,1% 0,0% 0,0% 0,0% 89,0% 9,6% 0,0% 0,0% 0,0% 0,0% 1,4% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 11,0% 0,0% 0,0% 100%U K R A I N EAvtonomnaya Respublika Krym 1 1 2 0 2Bolynskaja o. 3 3 6 11 1 12 18Cherkasskaja o. 8 9 2 1 20 13 13 33Chernigovskaja o. 3 20 6 29 3 1 4 33Chernovitskaja o. 1 1 2 4 0 4Dnepropetrovskaja o. 8 19 9 2 38 17 17 55Donetskskaja o. 14 7 13 34 19 1 20 54Ivano-Frankovskaja o. 1 1 2 2 2 4Khar'kovskaja o. 5 9 7 3 24 7 1 8 32Khersonskaja o. 7 9 6 1 23 5 5 10 33Khmel'nitskaja o. 5 14 17 1 37 18 18 55Kirovogradskaja o. 4 6 3 1 14 11 1 12 26Kiyevskaja o. 1 10 11 4 4 15Luganskaja o. 1 1 1 3 3 3 6L'vovskaja o. 4 1 5 12 12 17Nikolayevskaja o. 2 7 6 1 16 6 1 7 23Odesskaja o. 8 9 9 1 27 17 1 1 19 46Poltavskaja o. 1 4 5 0 5Rovenskaja o. 3 1 4 1 1 5Sumskaya o. 1 3 3 1 8 2 2 10Ternopol'skaja o. 4 4 8 1 9 13Vinnitskaja o. 14 18 4 36 104 3 107 143Zakarpatskaja o. 1 1 1 1 2Zaporozhskaja o. 9 26 18 2 55 18 2 3 1 24 79Zhitomirskaja o. 9 10 4 1 24 11 1 2 14 38TOTAL 114 192 110 3 13 0 0 0 432 291 15 0 4 0 4 1 0 0 0 0 0 4 319 0 0 751PER CENT 15,2% 25,6% 14,6% 0,4% 1,7% 0,0% 0,0% 0,0% 57,5% 38,7% 2,0% 0,0% 0,5% 0,0% 0,5% 0,1% 0,0% 0,0% 0,0% 0,0% 0,0% 0,5% 42,5% 0,0% 0,0% 100%13/27

dogcatcattleequinegoatsheeppigstray dogothersubtotalfoxracoondogracoonwolfbadgermartenothermustelidesothercarnivoreswild boarroe deerred deerfallowdeerothersubtotalbatHuman casestotal4.3 Rabies cases per country and administrative units, 4th quarter 2012 (continued) 01.10.12 - 31.12.12LocationDomestic animalsWildlifeT U R K E YAgri 2 6 1 9 0 9Ankara 1 2 3 1 1 4Artvin 1 1 0 1Aydin 4 4 0 4Balikesir 1 2 3 0 3Bingöl 3 3 0 3Bursa 0 1 1 1Diyarbakir 1 1 1 3 0 3Elazig 1 2 2 5 1 1 6Erzurum 3 1 4 0 4Eskisehir 1 1 0 1Giresun 4 4 0 4Hatay 1 1 2 0 2Igdir 5 9 1 15 0 15Istanbul 3 3 0 3Izmir 4 1 5 1 1 6Kütahya 1 1 0 1Malatya 1 2 1 4 1 1 5Manisa 3 1 4 1 1 5Nevsehir 1 1 0 1Sanliurfa 4 4 0 1 5Sirnak 1 1 0 1Tunceli 3 3 0 3Usak 0 1 1 1Van 1 2 3 0 3Zonguldak 2 2 0 2TOTAL 28 5 50 1 4 0 0 0 88 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 1 96PER CENT 29,2% 5,2% 52,1% 1,0% 4,2% 0,0% 0,0% 0,0% 91,7% 7,3% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 7,3% 0,0% 1,0% 100%S P A I NCiudad Autonoma de Melilla 2 2 0 1 3TOTAL 2 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 3PER CENT 66,7% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 66,7% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 33,3% 0,0% 100%T H E N E T H E R L A N D SFriesland 0 0 1 1Groningen 0 0 2 2TOTAL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 3PER CENT 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 100,0% 0,0% 100%14/27

dogcatcattleequinegoatsheeppigstray dogothersubtotalfoxracoondogracoonwolfbadgermartenothermustelidesothercarnivoreswild boarroe deerred deerfallowdeerothersubtotalbatHuman casestotal4.3 Rabies cases per country and administrative units, 4th quarter 2012 (continued) 01.10.12 - 31.12.12LocationDomestic animalsWildlifeR O M A N I AAlba 1 1 3 3 4Arad 2 2 0 2Arges 0 4 4 4Bacau 1 1 4 4 5Bihor 6 6 2 2 8Bistrita-Nasaud 1 1 11 11 12Botosani 4 4 5 1 6 10Braila 1 1 0 1Brasov 0 1 1 1Buzau 1 2 3 8 8 11Calarasi 2 2 1 1 3Cluj 0 2 2 2Constanta 0 2 2 2Covasna 0 1 1 1Dambovita 0 3 1 4 4Galati 0 2 2 2Giurgiu 1 1 2 0 2Gorj 1 1 1 3 0 3Harghita 0 3 1 4 4Ialomita 1 1 0 1Iasi 1 1 5 5 6Maramures 0 1 1 1Mures 1 1 6 6 7Neamt 1 1 2 2 3Olt 1 1 2 0 2Prahova 1 1 2 1 1 3Salaj 0 4 4 4Satu Mare 1 1 1 1 2Suceava 1 1 5 7 14 14 21Tulcea 1 1 2 3 3 5Valcea 1 1 1 1 2Vaslui 1 1 2 3 3 5Vrancea 1 1 3 3 4TOTAL 12 8 18 3 7 0 0 0 48 96 0 0 1 0 0 0 2 0 0 0 0 0 99 0 0 147PER CENT 8,2% 5,4% 12,2% 2,0% 4,8% 0,0% 0,0% 0,0% 32,7% 65,3% 0,0% 0,0% 0,7% 0,0% 0,0% 0,0% 1,4% 0,0% 0,0% 0,0% 0,0% 0,0% 67,3% 0,0% 0,0% 100%S E R B I A* no region specified 1 1 5 5 6TOTAL 0 1 0 0 0 0 0 0 1 5 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 6PER CENT 0,0% 16,7% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 16,7% 83,3% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 83,3% 0,0% 0,0% 100%15/27

dogcatcattleequinegoatsheeppigstray dogothersubtotalfoxracoondogracoonwolfbadgermartenothermustelidesothercarnivoreswild boarroe deerred deerfallowdeerothersubtotalbatHuman casestotal4.3 Rabies cases per country and administrative units, 4th quarter 2012 (continued) 01.10.12 - 31.12.12LocationDomestic animalsWildlifeR U S S I A N F E D E R A T I O NAstrahanskja obl. 1 10 11 1 1 12Belgorodskja obl. 16 25 6 1 1 49 26 2 28 77Brjanskaja obl. 1 2 4 1 8 8 4 12 20Cecenskaja resp. 15 15 0 15Cuvasskaja resp. 2 2 3 3 5Dagestan resp. 1 3 1 5 1 1 6Ivanovskaja obl. 1 1 1 1 2Jaroslavskaja obl. 0 5 4 9 9Kabardino-Balkanskaja resp. 1 1 2 0 2Kaliningradskaja obl. 1 1 1 1 2Kalmykija resp. 1 1 2 2 3Kaluzskaja obl. 1 3 1 1 6 5 2 7 13Kostromskaja obl. 0 1 1 1Krasnodarskij kr. 1 1 0 1Kurskaja obl. 4 7 3 14 15 2 17 31Lipeckaja obl. 4 8 6 1 19 34 1 35 54Marij El resp. 1 1 0 1Mordovija resp. 1 1 2 1 1 3Moskovskaja obl. 6 5 2 1 14 32 15 1 48 62Moskva g. 1 1 1 1 2Nizegorodskaja obl. 3 3 1 7 14 1 15 22Orlovskaja obl. 2 3 4 9 3 1 1 5 14Penzenskaja obl. 3 3 6 2 2 16 13 13 29Pskovskaja obl. 2 2 4 5 2 11 13Rostovskaja obl. 4 2 4 10 3 3 13Saratovskaja obl. 13 11 3 1 1 1 30 14 1 1 16 46Severnaja Osetija-Alanija resp. 8 2 6 1 17 1 1 18Smolenskaja obl. 3 1 4 4 1 5 9Stavropol'skij kr. 8 4 7 19 5 1 6 25Tambovskaja obl. 6 2 20 1 2 31 29 29 60Tul'skaja obl. 5 9 3 17 2 1 1 4 21Tverskaja obl. 1 5 1 7 9 28 1 38 1 46Ul'janovskaja obl. 7 4 2 13 18 1 19 32Vladimirskja obl. 4 4 1 1 5Volgogradskaja obl. 5 2 3 10 1 1 2 12Voronezskaja obl. 10 16 4 2 32 4 1 1 6 38TOTAL 115 139 104 4 12 2 5 0 381 255 69 0 2 4 3 4 1 0 2 0 0 2 342 0 1 724PER CENT 15,9% 19,2% 14,4% 0,6% 1,7% 0,3% 0,7% 0,0% 52,6% 35,2% 9,5% 0,0% 0,3% 0,6% 0,4% 0,6% 0,1% 0,0% 0,3% 0,0% 0,0% 0,3% 47,2% 0,0% 0,1% 100%S L O V E N I APodravska 0 1 1 1TOTAL 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1PER CENT 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 100,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 0,0% 100,0% 0,0% 0,0% 100%16/27

4.4 Summary of animals tested for rabies in Europe (total 2012)Name Code Total WildlifeDomesticanimals Bats RemarksALBANIA ALB no dataAUST RIA AUT * 3044 2922 122 0BELARUS BLR 419 97 322 0BELGIUM BEL* 530 48 374 108BOSNIA - HERCEGOVINA BIH 85 64 21 0BULGARIA BGR 798 784 14 0CROAT IA HRV 5601 4523 1076 2CYPRUSCYP*CZECH REPUBLIC CZH* 3533 3274 249 10DENMARK DNK* 17 0 3 14EST ONIA EST 224 164 56 4FINLAND FIN* 708 640 36 32FRANCE FRA* 2001 68 1578 355GERMANY DEU* 6791 6221 467 103GREECE GRC* 234 171 61 2HUNGARY HUN 4889 4191 681 17ICELAND ISL* 0 no dataIRELAND IRE* 0 no dataIT ALY IT A 6668 5929 736 3LAT VIA LVA 189 133 56 0LIT HUANIA LT U 549 373 176 0LUXEMBOURG LUX* 0 no dataMACEDONIA MKD 425 408 17 0MALT A MLT * 0 no dataMOLDOVA MDA 110 23 85 2MONT ENEGRO MNE 22 20 2 0NET HERLANDS NED* 208 6 25 177NORWAY NOR* 0POLAND POL 25320 23437 1779 104PORT UGAL PRT * 2 0 2 0ROMANIA ROU 0 no dataRUSSIAN FEDERAT ION RUS 0 no dataSERBIA SRB 216 112 103 1SLOVAK REPUBLIC SVK 3666 3410 255 1SLOVENIA SVN 2161 2056 105 0SPAIN ESP* 234 88 53 93SWEDEN SWE* no dataSWIT ZERLAND + LIEC. CHE* 74 14 45 15T URKEY T UR 845 19 826 0UKRAINE UKR 13381 9651 3717 13UNIT ED KINGDOM UNK* 410 0 2 408T OT AL 83354 68846 13044 146417/27

DifferenceDifferenceDifferenceDifferenceDifference4.5 Trend tables4.5.1 Comparison of the reporting quarter (IV/2012) with the previous quarter(III/2012)NAMEIV2012(no.)III2012(no.)IV2012(no.)III2012(no.)IV2012(no.)III2012(no.)Albania 2 -2 2 -2AustriaIV2012(no.)III2012(no.)Belarus 153 114 39 97 60 37 56 53 3 1 -1BelgiumBosnia - Hercegovina 3 1 2 3 1 2BulgariaCroatia 21 61 -40 21 49 -28 12 -12CyprusCzech RepublicDenmarkEstoniaFinlandFrance 1 8 -7 1 8 -7Germany 1 8 -7 1 8 -7Greece 9 9 7 7 2 2Hungary 1 -1 1 -1IcelandIrelandItalyKosovoLatviaLithuaniaLuxembourgMacedoniaMaltaMoldova 73 36 37 8 6 2 65 30 35MontenegroNorwayPoland 121 68 53 100 61 39 20 6 14 1 1PortugalRomania 147 70 77 99 40 59 48 30 18Russian Federation 724 413 311 342 253 89 381 160 221 1 1Serbia 6 6 5 5 1 1Slovak RepublicSlovenia 1 1 1 1Spain 3 2 1 2 2 1 1SwedenSwitzerland + Lichtenstein 1 -1 1 -1The Netherlands 3 4 -1 3 4 -1Turkey 96 146 -50 7 6 1 88 140 -52 1 1Ukraine 751 421 330 319 178 141 432 243 189United Kingdom * * * * *TOTAL 2113 1356 757 1009 654 355 1095 678 417 7 23 -16 2 1 1Wildlife: excluding batsTotal Wildlife Domestic animals Bats HumanIV2012(no.)III2012(no.)IV/2012 (no.), III/2012 (no.): number of casesDifference: no. of cases in IV/2012 minus cases in III/201218/27

DifferenceDifferenceDifferenceDifferenceDifference4.5.2 Comparison of the reporting quarter (IV/2012) with the same quarter ofthe previous year (IV/2011)NAMEAlbaniaAustriaIV2012(no.)IV2011(no.)IV2012(no.)IV2011(no.)Belarus 153 * 153 97 * 97 56 * 56 * *BelgiumIV2012(no.)IV2011(no.)Bosnia - Hercegovina 3 2 1 3 1 2 1 -1BulgariaCroatia 21 98 -77 21 63 -42 35 -35CyprusCzech RepublicDenmarkEstoniaFinlandIV2012(no.)IV2011(no.)France 1 1 1 1Germany 1 3 -2 1 3 -2Greece 9 9 7 7 2 2HungaryIcelandIrelandItaly 1 -1 1 -1KosovoLatvia 1 -1 1 -1Lithuania 4 -4 4 -4LuxembourgMacedoniaMaltaMoldova 73 35 38 8 9 -1 65 26 39Montenegro 9 -9 8 -8 1 -1NorwayPoland 121 40 81 100 32 68 20 8 12 1 1PortugalRomania 147 151 -4 99 118 -19 48 33 15Russian Federation 724 458 266 342 216 126 381 240 141 1 2 -1Serbia 6 9 -3 5 7 -2 1 2 -1Slovak RepublicSlovenia 1 1 1 1Spain 3 3 2 2 1 1SwedenSwitzerland + LichtensteinThe Netherlands 3 1 2 3 1 2Turkey 96 72 24 7 14 -7 88 58 30 1 1Ukraine 751 626 125 319 301 18 432 325 107United KingdomTotal Wildlife Domestic animals Bats HumanTOTAL 2113 1510 603 1009 773 236 1095 730 365 7 4 3 2 3 -1Wildlife: excluding bats IV/2012 (no.), IV/2011 (no.): number of casesDifference: no. ofcases in IV/2012 minus cases in IV/2011, *no dataIV2012(no.)IV2011(no.)19/27

List of ContributorsALB AlbaniaKujtim Mersini, DVM, MScNational Veterinary Epidemiology UnitFood Safety and Veterinary InstituteRr. Aleksandër Moisiu no.10Tirana / AlbaniaTel.: +355 4 2373096Fax: +355 682738752Email: mersini2003@yahoo.comAUT AustriaMag. Ulrich Herzog, CVOBundesministerium für Gesundheit undFrauenBereich IV/B (Verbraucher-Gesundheit)Radetzkystraße 2A-1030 WienTel. +43-1-7 11 00-4824Fax +43-1-7 10 41 51E-mail: ulrich.herzog@bmgf.gv.atBLR BelarusDr. A.M. AxenovHead of the Central Board of VeterinaryMedicineMinistry of Agriculture and FoodKirova 15Minsk /BelarusTel: +375-17-227 6623Fax: +375-17-227 42 96+375-17-227 57 54E-mail: vetinsp@mshp.minsk.byBEL BelgiumDr. Pierre Naassens, CVOAFSCA – Agence fédérale pour laSécurité de la Chaîne alimentaireDirection Générale de la Politique deContrôle55, Boulevard du Jardin BotaniqueB-1000 BruxellesTel. +32-2-211 86 42Fax +32-2-211 86 30Responsible experts:Dr. Bernard Brochier; Dr. Vanessa Suin;Dr. Steven Van GuchtNational Reference Centre of RabiesViral DiseasesScientific Institute of Public Health (WIV-ISP)Rue Engelandstraat 6421180 BrusselsBelgiumBIH Bosnia and HerzegovinaDepartment of Infectious DiseasesVeterinary Faculty SarajevoZmaja od Bosne 90Sarajevo 71000 /Bosnia andHerzegovinaTel: +387-61-160 361E-mail: vetzar@bih.net.baDr. Sc. Drago N. NedicMinistry Agriculture, Forestry andWater Management of Republika SrpskaMilosa Obilica 5176300 Bijeljina, Republika SrpskaBosnia and HerzegovinaTel: +387-55-401 812,-211 506-403 508Fax: +387-55-403 508-472 353E-mail: nedicd@rstel.netnedicd@vetservice.orgWeb: www.vetservice.orgBUL BulgariaDr. Petya PetkovaNational Veterinary ServiceAnimal Health Directorate15A “Pencho Slaveikov” blvd.1606 Sofia, BulgariaTel: +359 2 915 98 42Fax: +359 2 952 38 35HVR CroatiaDr. Ljerka ZebaVeterinary AdministrationMinistry of Agriculture and ForestryVukovarska 7810000 Zagreb, Republic of CroatiaTel: +385 1 6106207Fax: +385 1 6109207E-mail: ljerka.zeba@mps.hrCYP CyprusDr. P. Economides, CVODirector of Veterinary ServicesMinistry of Agriculture, NaturalResources and Environment - VeterinaryServices -1417 Nicosia /CyprusTel. +357-2-80 52 0Fax +357-2-33 28 03E-mail vet.services@cytanet.com.cy20/27

CZH Czech RepublicMVDr. Josef VitásekState Veterinary Administration CRSlezská 7CZ – 120 00 Praha 2 / Czech RepublicTel.: +420 – 227 010 144Fax : +420 – 227 010 195E-mail: j.vitasek@svscr.czResponsible expert:MVDr. Ivan NáglNational Reference Laboratory for RabiesState Veterinary Institute PragueSídlištní 136/24CZ -165 03 Praha 6 – LysolajeTel. +420 251 031 281Fax +420 220 920 655E-mail:i.nagl@svupraha.czDNK DenmarkDr. Per Henriksen, CVOMinistry for Food, Agriculture andFisheriesDanish Veterinary and FoodAdministrationStationsparken 31-33DK-2600 GlostrupTel.: +45 7227 6900Email: pesh@fvst.dkResponsible expert:Tina MørkMinistry for Food, Agriculture andFisheriesDanish Veterinary and FoodAdministrationStationsparken 31-33DK-2600 GlostrupTel.: +45 7227 6541Email: tm@fvst.dkEST EstoniaDr. Matti Nautras, CVOHead of Animal Health DepartmentVeterinary and Food Broad of EstoniaVäike-Paala-Street 311415 Tallinn /EstoniaTel. +372-605 1732Fax +372-638 0210E-mail nautras@vet.agri.eeResponsible expert:Dr. Külli MustHead of DepartmentVeterinary and Food LaboratoryKreutzwaldi 3051006 Tartu /EstoniaTel: +372-742 1246Fax: +372-742 1730E-mail: kylli@vetlab.eeFIN FinlandDirector General Dr. Matti Aho, CVOMinistry of Agriculture and ForestryDepartment of Food and HealthPO BOX 30FI-00023 GovernmentFinlandTel: +358 9 160 53380Fax: +358 9 1605 4777,+358-9-1605 3338E-mail cvo-finland@mmm.fiResponsible expert:Tiia TuupanenFinnish Food Safety Authority EviraMustialankatu 3, FI-00790 Helsinki,Finlandtel. +358 40 489 3348fax +358 20 77 24355E-mail: tiia.tuupanen@evira.fiWeb: www.mmm.fiFRA FranceDr. Florence CliquetANSESNancy laboratory for rabies and wildlifeTechnopôle Agricole et VétérinaireBP 4000954220 Malzéville, FranceTel: +33-3-83.29.89.50Fax: +33-3-83.29.89.59E-mail: f.cliquet@nancy.afssa.frWeb: www.anses.fDEU GermanyDr. Karin Schwabenbauer, CVOFed. Ministry of Food, Agriculture andConsumer ProtectionPF 14 02 70, D-53103 Bonn, GermanyTel: +49 228 529 41 5Fax: +49 228 529 35 53E-mail: poststelle@bmelv.bund.deResponsible experts:Dr. Thomas MüllerDr. Conrad FreulingWHO Collaborating Centre for RabiesSurveillance and ResearchInstitute of Molecular Biology, Friedrich-Loeffler-Institute- Federal Research Institute for AnimalHealth –Südufer 10, 17493 Greifswald - InselRiems, Germanytel: ..49 38351 71660/659fax: ..49 38351 71174email:who-rabies@fli.bund.de21/27

GRC GreeceKonstantia TasioudiInstitute of Infectious and Parasiticedisease25 Neapoleos street. Agia Paraskevi15310GreeceTel, Fax:+30 210 6011499viruslab.ath@gmail.comHUN HungaryDr. Tibor BalintDr. Zsolt FöldiMinistry of Agriculture and RegionalDevelopmentAnimal Health and Food ControlDepartmentH-1860 Budapest 55. Pf. 1Tel. +36-1 3014329 and 332 7986Fax +36-1 301 4669E-mail foldiz@oai.huISL IcelandDr. Halldor RunolfssonChief Veterinary OfficerMinistry of Agriculture, VeterinaryServicesSolvholsgata 7150 Reykjavik /IcelandTel. +354-560 9750Fax +354-552 1160E-mail halldor.runolfsson@lan.stjr.isIRE IrelandDr. J. MelvilleSuperintending Veterinary InspectorDepartment of Agriculture, Food andForestryAgriculture HouseDublin 2/IrlandTel: +353-1-607 2981Fax: +353-1-661 2440Responsible expert:Dr Patrick LenihanSenior Superintending Research OfficerVirology DivisionCentral Veterinary Research LaboratoryAbbotstown, BlanchardstownDublin 15ITA ItalyDr. Franco MutinelliIstituto ZooprofilatticoSperimentale delle VenezieViale dell'Università, 10I-35020 Legnaro (PD) /ItalyTel: +39-049-80 84 259Fax: +39-049-80 84 258E-mail: fmutinelli@izsvenezie.it22/27LVA LatviaDr. Mareks SamohvalovsDr. Emils JegersFood and Veterinary ServicePeldu Street 30,Riga, LV-1050, LatviaTel: +371 67095230Fax: +371 67322727E-mail: pvd@pvd.gov.lvLTU LithuaniaDr. K. LukauskasDr. V. Kiudulas,Animal Health DepartmentState Food and Veterinary ServiceSiesikų 19, LT-07170 VilniusE-mail: vvt@vet.ltvkiudulas@vet.ltLUX LuxembourgDr. Arthur Besch, CVOInspection VétérinaireGrand-Duché de LuxembourgAdministration des Services vétérinaires93, rue d‘AnversBoîte postale 1403L-1014 LuxembourgTel: +352-478 2539Fax: +352-407 545E-mail: Arthur.Besch@asv.etat.luMKD MacedoniaSloboden Cokrevski, DVMMinistry ofAgriculture, Forestry and WaterEconomyVeterinary DirectorateRepublic of MacedoniaLeninova 21000 Skopje/MacedoniaTel: + 389 2 3210468Fax: + 389 2 3210315E-mail: scokrevski@veterina.gov.mkResponsible expert:Prof. Dr. Misho HristovskiSlavcho Mrenoshki, DVM, MSc, PhD,Associate ProfessorFaculty of Veterinary Medicine SkopjeDepartment of Microbiology andImmunologyLazar Pop-Trajkov 5-7, 1000 Skopje,MacedoniaTel: + 389 2 3240768Fax: + 389 2 3114619E-Mail: mrenoski@fvm.ukim.edu.mkWeb: http://www.fvm.ukim.edu.mk/MNE MontenegroMevlida Hrapovic

Veterinary administration of the Republicof MontenegroBulevar Sv.Petra Cetinjskog br 981000 Podgorica, MontenegroTel: +38 2 81 201 945;Fax: +38 2 81 201 946e-mail: mevlida.hrapovic@vu.gov.meMDA MoldovaVsevolod Stamati,Animal Health DivisionDepartment of Veterinary MedicineMinistry of Agriculture and Food IndustryRepublic of MoldovaE-mail: dmv@maia.gov.mdNED NetherlandsDr. P.W.de LeeuwDutch Ministry of Agriculture, Nature andFoodBezuidenhoutseweg 73 - P.O. Box 20401NL-2500 EK‘s-Gravenhage /NetherlandsDr. L. ZüchnerFood en Consumer Product SafetyAuthorityDe Stoven 22NL-7206 AX Zutphen /NetherlandsTel: +31-575-58 8 100Fax: +31-575-588 8 200E-mail: lothar.zuchner@vwa.nl24-100 Pulawy/PolandTel.: +48 81 889 32 61Fax: +48 81 886 25 95Email: jfzmudzi@piwet.pulawy.plPawel Makowski, DVMAnimal Health and Welfare OfficeGeneral Veterinary InspectorateVeterinary Inspection30, Wspolna Str.00-930 Warsaw/PolandTel.: +48 22 623 22 42Fax: +48 22 623 14 08Email: pawel.makowski@wetgiw.gov.plPRT PortugalDr.C.A.M.de AndradeFontesDireccao-Geral da PecuariaROU RomaniaProf. Gabriel Predoi, CVOGeneral Director of the SanitaryVeterinary General Direction, NationalSanitary Veterinary and Food SafetyAuthorityBd. Carol I, nr. 24, sector 3Bucuresti, cod 70.033 /RomaniaTel: +40-21-3157875Fax: +40-21-3124967E-mail: predoi@ansv.roNOR NorwayDr. Keren Bar-Yaacov, CVONorwegian Food Safety Authority, HeadOfficeP.O. Box 383N-2381 Brumunddal, NorwayTel: +47 23 21 68 00Fax: +47 23 21 68 01E-mail: postmottak@mattilsynet.noPOL PolandJanusz Zwiazek, DVMChief Veterinary OfficerGeneral Veterinary InspectorateVeterinary Inspection30, Wspolna Str.00-930 Warsaw/PolandTel.: +48 22 623 20 89Fax: +48 22 623 14 08Email: wet@wetgiw.gov.plPOL PolandResponsible expert:Prof. Jan F. ZmudzinskiNational Veterinary Research InstituteDepartment of VirologyNational Reference Laboratory for Rabies57 Partyzantow Avenue23/27RUS Russian Federation(European part)Prof. V.A.VedernikovDr. I.V.BaldinaThe Kovalenko All-RussianInst.of Exper. Veterinary Medicine109455, Moscow, Ryazanskу prosp., 24Tel: +495 377-9483Fax: +495 970-0369E-Mail: epizootviev@mail.ruDr.N.A.YaremenkoDr. S.A.KolomytzevDepartament of veterinary and livestockMinistry of Agriculture107139, Moscow, Orlikov per., 1/11Tel: +495 975-5423Fax: +495 975-5423E-mail: n.yaremenko@vet.mcx.ruResponsible expert:Dr Artem MetlinFederal Centre for Animal Health,600901, Vladimir,Russia.Fax +74 922260753E-mail artem.metlin@inbox.ruProf. A.A.Movsesyants

Scientific Centre of Expertise of MedicalsDevices119002, Moscow,Per. Sivtzev Vrazhek, 41Tel. +7 499 2413784E-mail: Movsesyans_AA@gisk.ruSRB SerbiaProf. Dr Dušan Lalošević (Director)Dr. Nenad Vranješ (Rabies Epidemiologyand prevention)Dr. Srđan Stankov (Rabies laboratory)Pasteur Institute Novi SadHajduk Veljkova 1 / P.O. Box 20821000 Novi Sad / SerbiaTel.: +381 21 6611 003+381 21 420 528Fax: +381 21 6611 003Email: paster-ns@neobee.netESP SpainIlmo. Sr. D. Pedro Angel García GonzálezSubdirector General de Sanidad ExteriorTel: +34-91-596 20 38Fax: +34-91-596 20 47E-mail: pgarciag@msc.esSr. D. Carlos Abellán GarcíaJefe de Servicio de Veterinaria OficialTel: +34-91-596 19 34Fax: +34-91-596 20 47E-mail: cabellan@msc.esMinisterio de Sanidad y ConsumoDirección General de Salud PúblicaSubdirección General de SanidadExteriorC/Paseo del Prado, 18-20E-28071 MadridSVK Slovak RepublicProf. Josef Bires, CVORoman Matejcik, DVMState Veterinary Administration of theSlovak RepublicBotanická No 17842 13 Bratislava /Slovak RepublicTel. +421-2-60 257 227Fax +421-2-65 411 159E-mail welfare@svssr.skResponsible expert:Miroslav Mojziš, DVMŠtátny veterinárny ústav ZvolenPod Dráhami No. 918960 86 Zvolen /Slovak RepublicSVN SloveniaAleš Brecelj, MSc, DVMMinistry of Agriculture, Forestry andFoodVeterinary Administration of the Republicof SloveniaParmova 53, 1000 Ljubljana / SLOVENIATel: +386-1-300 13 00Fax: +386-1-300 13 56E-mail: ales.brecelj@gov.siWeb: www.sigov.si/vursResponsible expert:Peter Hostnik, PhD, DVMNational Veterinary Institute, Unit for thediagnostic of contagious and otherdiseases,Laboratory of VirologyGerbičeva 601000 Ljubljana / SLOVENIATel: +386-1-477 91 00Fax: +386-1-477 93 52E-mail: peter.hostnik@vf.uni-lj.si24/27Responsible expert - Diagnóstico:Sr. D. Juan E. Echevarría MayoServicio de Microbiología DiagnósticaCentro Nacional de MicrobiologíaInstituto de Salud Carlos IIIMinisterio de Sanidad y ConsumoCtra. Majadahonda-Pozuelo s/n28220 Majadahonda, MadridTel: +34-91-509 79 01Fax: +34-91-509 79 66E-mail: jeecheva@isciii.esEpidemiología:Sra. Da Luisa Pilar Sánchez SerranoCentro Nacional de EpidemiologíaInstituto de Salud Carlos IIIMinisterio de Sanidad y ConsumoC/ Sinesio Delgado, 6E-28029 MadridTel: +34-91-387 78 02Fax: +34-91-387 78 16E-mail: Isanchez@isciii.esDr. Ignacio Sanchez EstebanSubdirector General de SanidadVeterinariaMAPAMinisterio de Agricultura, Pesca yAlimentacionMadrid /SpainTel: +34-91-347 82 95Fax: +34-91-347 82 99E-mail: isanchez@mapya.esWeb: www.mapya.esResponsible expert:D. Fulgencio Garrido AbellanTel: +34-958-44 03 75Fax: +34-958-44 12 00E-mail: fgarrido@moebius.es

Dña. Teresa Rodríguez-TrenchsTel: +34-91-347 83 4Fax: +34-91-347 82 99E-mail: trodrigu@mapya.esSWE SwedenDr. Leif DennebergNational Board ofAgricul¬tureDepartment for AnimalProduction and HealthSE-551 82 Jönköping /SwedenTel. +46-36-15 50 00Fax: +46-36-30 81 82E-mail: leif.denneberg@sjv.seResponsible expert:Professor Anders EngvallNational Veterinary InstituteSE-751 89 UppsalaTel: +46-18-67 40 00Fax: +46-18-67 44 45E-mail: anders.engvall@sva.seCHE SwitzerlandPD Reto ZanoniDr. Urs BreitenmoserUniversity of Bern - Swiss Rabies CentreInstitute of Veterinary VirologyLänggass Str. 122CH-3012 Bern /SwitzerlandTel: +41-31-631 23 78Fax: +41-31-631 25 34E-Mail: zanoni@ivv.unibe.chbreitenmoser@ivv.unibe.chWeb: www.cx.unibe.ch/ivvTUR TurkeyAsso.Prof.Dr. Muzaffer AYDEMİRMinistry of Agriculture and Rural AffairsGeneral Directorate of Protection andControlEsat cad. No. 306100 Bakanliklar, Ankara /TurkeyTel: +90-312-41 82 436Fax: +90-312-41 78 209Responsible expert:Dr. Orhan Aylan, Chief of RabiesLaboratoryEtlik Central Veterinary Control andResearch Institute06020 Etlik, Ankara /TurkeyTel: +90-312-32 60 090 / 154Fax: +90-312-32 11 755Grinchenko,101001 Kyiv/UkraineTel.: +380 44 279 12 70Fax: +380 44 279 48 83Dr. Zhanna DrozhzheHead of Virology DepartmentState Research Institute of LaboratoryDiagnostics and Veterinary SanitaryExpertiseDonetskaja Street 3003151 Kyiv/ UkraineTel.: +380-44-243 37 55Fax: +380-44-242-37 55Email: biotech@astral.kiev.uaUNK United KingdomMr Nigel Gibbens BVetMed MSc MRCVS,CVOMr David Mouat BVM&S MSc MRCVSMr Balazs Toth DrMedVet MRCVSDepartment for Environment, Food andRural AffairsArea 5D Nobel House17 Smith Square, London SW1P 3JRTel. +44-207-238 6047Fax +44-207-238 5051e-mail david.c.mouat@defra.gsi.gov.ukbalazs.toth@defra.gsi.gov.ukResponsible expert:Dr Anthony R Fooks MBA PhD CBiol FSBHead of Wildlife Zoonoses and Vector-Borne Diseases Research GroupStatutory and Exotic Viruses Sub-Programme ManagerAnimal Health and VeterinaryLaboratories Agency (AHVLA)Woodham Lane, New HawAddlestone, Surrey. KT15 3NB UKTel: +44 1932 357840+44 7733 308313Fax: +44 1932 357239GTN: 3956 2840E-mail: Tony.Fooks@ahvla.gsi.gov.ukWeb: www.defra.gov.uk/ahvlaPlease inform the editor aboutchanges of contact details!UKR UkraineDr. V.GorzheevMinistry of Agrarian PolicyState Department of Veterinary andPhytosanitary Service of Ukraine25/27