Flavonol glycosides and triterpenes from the leaves of Uncaria ...

Flavonol glycosides and triterpenes from the leaves of Uncaria rhynchophylla (Miq.) Jacks. / Asian Journal of TraditionalMedicines, 2009, 4 (3)(2H, d, J = 8.6 Hz, H-3’, 5’), 6.41 (1H, s, H-8), 6.19(1H, s, H-6), 5.32 (1H, d, J = 7.6 Hz, gal-1’’), 4.40(1H, s, rha-1’’’), 1.06 (3H, d, J = 6.0 Hz, rha-6’’’). 13 C NMR (75 MHz, DMSO-d 6) see Table 1. Alldata were identical to those of kaempferol-3-O-α-Lrhamnopyranosyl-(1→6)-β-D-galactopyranoside[7] .Compound 5Amorphous yellow powder, m.p. 238-240 °C. HCl-Mg reaction and Molish reaction: positive. UV (MeOH)λ max: 266, 353 nm. ESI-MS (m/z): 471 [M+Na] + , 487[M+K] + , 447 [M-H] - . Molecular formula: C 21H 20O 11.1H NMR (300 MHz, DMSO-d 6): δ H12.60 (1H, s,-OH-5), 10.31 (1H, s, -OH-7), 8.07 (2H, d, J = 8.7 Hz,H-2’, 6’), 6.86 (2H, d, J = 8.7 Hz, H-3’, 5’), 6.43 (1H,s, H-8), 6.21 (1H, s, H-6), 5.41 (1H, d, J = 7.5 Hz,gal-1’’). 13 C NMR (75 MHz, DMSO-d 6) see Table 1.All data were identical to those of kaempferol-3-O-β-D-galactopyranoside [8] .Compound 6Table 1. 13 C NMR (75 MHz) data of compounds 1–5 (DMSO-d 6)Position 1 2 3 4 52 156.4 156.5 156.4 156.6 156.43 133.6 133.4 133.5 133.4 133.34 177.5 177.5 177.5 177.5 177.65 161.3 161.3 161.3 161.3 161.36 98.8 98.8 98.7 99.0 98.87 164.3 164.2 164.2 164.0 164.38 93.7 93.7 93.6 93.9 93.89 156.4 156.7 156.3 156.6 156.410 104.0 104.0 104.0 103.8 104.01' 121.1 121.3 121.1 120.9 121.02' 115.3 115.3 115.2 131.0 131.13' 144.9 144.8 144.9 115.1 115.24' 148.6 148.5 148.5 160.1 160.15' 116.0 116.3 116.0 115.1 115.26' 122.0 121.7 122.0 131.0 131.11'' 102.1 101.3 101.8 102.2 101.72'' 71.2 74.2 71.3 71.2 71.33'' 73.1 76.5 73.2 73.1 73.24'' 68.4 70.1 68.0 68.1 68.05'' 73.6 76.5 75.9 73.6 75.96'' 65.2 67.1 60.2 65.4 60.31''' 100.1 100.8 100.12''' 70.5 70.5 70.53''' 70.7 70.6 70.74''' 72.0 71.9 72.05''' 68.1 68.3 68.46''' 18.0 17.8 18.088