Collo quium 2011

Colloquium 2011
Collaborative Research Centre
SFB 599
Biomaterial Engineering
Sustainable Bioresorbable and
Permanent Implants of Metallic
and Ceramic Materials
Hannover
October 14-15, 2011
University of Veterinary Medicine Hannover (TiHo)
Clinic for Small Animals
Bünteweg 9 – 30559 Hannover
Lecture Hall „Bayer“

Welcome
Dear Participants,
We would like to invite you to join the colloquium of
our Collaborative Research Centre SFB 599 „ Sustainable
Bioresorbable and Permanent Implants of Metallic and
Ceramic Materials“ in Hannover on October 14-15, 2011.
The aim of the colloquium is to stimulate an exchange
of knowledge and experience between researchers
of the SFB 599, external scientists and industry. We
will present the latest results of our research projects.
Further, we have been able to win excellent national
and international scientists who will report about their
experience in the field of biomedical technology.
Due to the necessary arrangements we kindly ask you
to register with Ms. Regina Müller;
phone +49 (0)511 532-3026,
e-mail: mueller.regina@mh-hannover.de
Yours sincerely,
Prof. Prof. h.c. Dr. med. Thomas Lenarz
Spokesman of SFB 599

Program: Friday, October 14 th
09:30 Welcome
Subject Area EAR
10:00 D2 Multimodal functionalization of electrodes
Prof. Thomas Lenarz
Hannover Medical School, Germany
10:15 Surface functionalization with
self-regenerating properties
Dr. Peter Thomsen
BioModics ApS, Lyngby, Denmark
10:45 D1 Mesoporous silica layers on implants:
Application in the middle ear
Prof. Peter Behrens
Leibniz Universität Hannover, Germany
11:00 Mesoporous silica nanoparticles
for targeted cancer therapy
Prof. Mika Lindén
University of Ulm, Germany
11:30 T2 Surface functionalization of cochlear
implants with ultra-short puls lasers
Elena Fadeeva
Laser Zentrum Hannover e.V., Germany
11:45 Time domain based impedance measurement
for electrical characterization of cells and
tissue
PD Dr. Uwe Pliquett
Institute for Bioprocessing and Analytical
Measurement Techniques e.V., Heilbad
Heiligenstadt, Germany
12:15 LUNCH BREAK
Subject Area JOINT
13:15 D4 Fully ceramic knee implants –
challenges and solutions concerning
machining processes
Prof. Berend Denkena
Leibniz Universität Hannover, Germany
13:30 Computer-integrated knee surgery system
Prof. Mamoru Mitsuishi
The University of Tokyo, Japan

Program: Friday, October 14 th
14:00 D6 FE simulation of strain-adaptive bone
remodeling in the hip joint after THR
M. Sc. Nelly Weigel
Leibniz Universität Hannover, Germany
14:15 Ceramic scaffolds for bone regeneration:
in vitro and in vivo studies
Prof. Dr. Wiltrud Richter
Heidelberg University Hospital, Germany
14:45 D7 Thin polymer layers – biomedical
perspective and analytical challenge
Dr. Wibke Dempwolf
Technische Universität Braunschweig, Germany
15:00 The pool of „high tech“ instrumentation in the
research building of the Mainz University Medical
Center
Univ.-Prof. Dr. Heinz Duschner
Mainz University, Germany
15:30 BREAK
16:00 D13 Metal forming adapted design method for
patient individual acetabular components
Dipl.-Ing. Stefanie Betancur Escobar
Leibniz Universität Hannover, Germany
16:15 Production of standard and
patient individual hip implants
Dr.-Ing. Marc Kneissler
Biomet Deutschland GmbH, Berlin, Germany
16:45 DR1 Options and therapeutic strategies
in infections of joint prostheses
Prof. Henning Windhagen
Hannover Medical School, Germany
17:00 Protein Coupling for enhanced fixation
in permanent bone implants
Prof. Marcus Jäger
Essen University Hospital, Germany
17:30 BREAK

Program: Friday / Saturday, October 15 th
18:00 Bio-inspired intracellular recordings and
stimulation of neurons by extracellular
multisite noninvasive gold mushroom
shaped multi electrode array
Prof. Micha E. Spira
The Hebrew University of Jerusalem, Israel
19:30 Appetizers for Mind and Mouth – Convivial
Evening in the Kestnergesellschaft
Goseriede 11, Hannover
Current Exhibition: Daniel Richter: 10001nights
Saturday, October 15 th
Subject Area BONE
08:30 R6 Reactions of osseous - and lymphoid tissue
after implantation of magnesium alloys for
orthopaedic applications in comparison to
conventional osteosynthesis materials
Dr. Janin Reifenrath
Hannover School of Veterinary Medicine,
Germany
08:45 Histological and immunohistochemical
methods for the evaluation of osseous
and lymphoid tissue alterations
Dr. Alexandr Bondarenko
Dnipropetrovs‘k State Medical Academy,
Ukraine
09:15 D10 New approaches for active
improvement of fracture healing
Dr. Christian Müller
Hannover Medical School, Germany
09:30 TBD
10:00 T3 Design and machining of load bearing
resorbable large fragment screws
Patrick Helmecke
Leibniz Universität Hannover, Germany
10:15 TBD
10:45 BREAK

Program: Saturday, October 15 th
Subject Area TOOTH
11:15 D8 Novel surface coatings for prevention of biofilm
formation on medical implant surfaces
Prof. Meike Stiesch
Hannover Medical School, Germany
11:30 Strategies for antibacterial implants
Prof. Dr. Regine Willumeit
Helmholtz-Zentrum Geesthacht, Germany
12:00 D12 Investigation of new fillers in dental
composites
Prof. Henning Menzel
Technische Universität Braunschweig, Germany
12:15 New components for restorative composites
Prof. Norbert Moszner
Ivoclar Vivadent AG, Schaan, Liechtenstein
12:45 LUNCH BREAK
Subject Area HEART/VESSELS and
PARANASAL SINUSES
13:45 R1 Simulation models for calcification
and application to stents
Prof. Peter Wriggers
Leibniz Universität Hannover, Germany
14:00 Modeling and simulation of stent implantation
in arteries: opportunities for the future
Prof. Gerhard Holzapfel
Graz University of Technology, Austria
14:30 R7 Stabilizing of tissue engineered aortic
prostheses by the use of bioresorbable
magnesium alloy structures
Dr.-Ing. Thomas Hassel
Leibniz Universität Hannover, Germany
14:45 TBD
15:15 R8 Behavior of magnesium under
different physical conditions
Florian Evertz
Leibniz Universität Hannover, Germany
15:30 TBD
16:00 Goodbye

Subprojects of the Third Funding Period
2011 – 2014
Section R: Bioresorbable Implants
R1 Magnesium degradation
Bormann/Bach, Lenarz, Kietzmann
R6 Degradable osteosynthesis systems
Meyer-Lindenberg, Wriggers, Thorey
R7 Structures made of magnesium for the stabilization
of cardiovascular tissue scaffolds in the high
pressure system
Haverich, Hassel
R8 Control of the degradation and mode of action of
magnesium-based medical implants
Glasmacher, Hauser, Kietzmann
Section D: Permanent Implants
D1 Functionalized middle ear prostheses
P. Behrens, Müller, Stieve
D2 Development of electrode-arrays for optimised
electrode-nerve-interaction
Lenarz, Chichkov, Menzel
D4 Ceramic implants
Denkena, Hurschler
D6 Numerical simulation on stress-compatible
design of total prosthetic joint replacements and
implants
B.-A. Behrens, Stukenborg-Colsman, Nolte
D7 Implant surfaces
Windhagen, Dempwolf, Gross
D8 Chemical functionalization of dental implant
abutments for reduction of oral biofilm formation
Stiesch, Menzel, Abraham

Subprojects of the Third Funding Period
2011 – 2014
D9 Biomimetic ceramics
Menzel, Ostermeier, Glasmacher
D10 Implants with alterable stiffness
Gösling, Barcikowski, Hurschler
D12 Dental ceramics and composites
P. Behrens, Stiesch, Jendras
D13 Development, metal-forming and evaluation of
patient-individual cetabular components
Bouguecha, Wefstaedt, Stukenborg-Colsman
Section DR: Permanent Implants with bioresorbable
component
DR1 Mg-compounds on permanent implants
Windhagen, Möhwald, Hauser
Section T: Transfer
T2 Nano-functionalized cochlear implants for
optimized electrode-nerve-interaction
Paasche, Chichkov, Lenarz
T3 Design, safe machining and performance of load
bearing resorbable large fragment screws made
of magnesium
Denkena, Windhagen

Participating Institutions
Hannover Medical School (MHH)
o Department of Otolaryngology (HNO)
� Consolidated Institute for Audio- Neurotechnology
and Nanobiomaterials (VIANNA)
o Department of Orthopedics, Annastift
� Laboratory for Biomechanics and Biomaterials (LBB)
o Department of Cardiothoracic, Transplantation and
Vascular Surgery (HTTG)
� Leibniz Research Laboratories for Biotechnology
and Artificial Organs (LEBAO)
o Department of Trauma Surgery (UCH)
o Department of Prosthetic Dentistry and Biomedical
Materials Science (ZPR)
o Institute for Cellular Biology in the Centre for Anatomy
Leibniz Universität Hannover (LUH)
o Institute of Inorganic Chemistry (ACI)
o Institute of Production Engineering and Machine
Tools (IFW)
o Institute of Continuum Mechanics (IKM)
o Institute of Multiphase Processes (IMP)
o Institute of Metal Forming and Metal Forming
Machine Tools (IFUM)
o Institute of Materials Science (IW)
University of Veterinary Medicine Hannover (TiHo)
o Clinic for Small Animals (KKT)
o Department of Pharmacology, Toxicology &
Pharmacy (PTP)
Helmholtz Centre for Infection Research,
Braunschweig (HZI)
Laser Zentrum Hannover e.V.
Technische Universität Braunschweig
o Institute of Technical Chemistry (ITC)

Key Contacts
Spokesman
Prof. Prof. h.c. Dr. med. Thomas Lenarz
Professor and Chairman
Department of Otolaryngology
Hannover Medical School
Tel.: +49 (0)511 532-6565
Fax: +49 (0)511 532-5558
E-Mail: lenarz.thomas@mh-hannover.de
SFB 599 Office
Regina Müller
Department of Otolaryngology
Hannover Medical School
Carl-Neuberg-Str. 1
30625 Hannover
Tel.: +49 (0)511 532-3026
Fax: +49 (0)511 532-5558
E-Mail: mueller.regina@mh-hannover.de
Managing Director
Dr. rer. nat. Johannes Stein
Department of Otolaryngology
Hannover Medical School
Tel.: +49 (0)511 532-9194
Fax: +49 (0)511 532-5558
E-Mail: stein.johannes@mh-hannover.de
Homepage: www.sfb599.de
The Collaborative Research Centre SFB 599 is funded by the
DFG Deutsche Forschungsgemeinschaft.

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Kindly return this information to Regina Müller by 30 September 2011

Arrival
Arrival from main station
Take the underground U1 in direction of Laatzen /
Sarstedt, U2 in direction of Rethen or U8 in direction
of Messe/Nord until you reach the station Aegidientorplatz.
From there, change to U6 (Messe Ost) until you
reach the station Bünteweg / Tierärztliche Hochschule.
The “TiHo Tower” is situated in front of the station, approximately
3 minute walk to Bünteweg 9.
Arrival by car
Arrival from the north, west or east:
Follow the motorway A37 (Messeschnellweg) in
southward direction and take exit Bult. Then turn left in
direction Bemerode. Bünteweg is behind the railroad
bridge on the left side.
Arrival from the south:
Follow the motorway A37 (Messeschnellweg) in
northward direction (Celle) and take exit Bult. Then turn
left in direction Bemerode. Bünteweg is behind the
railroad bridge on the left side.
University of Veterinary Medicine Hannover (TiHo)
Klinik für Kleintiere – Clinic for Small Animals
Bünteweg 9
30559 Hannover
Lecture Hall „Bayer“