Introducing BioLaz - CPAC

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Biological Particle Generator• Ink Jet Aerosol Generator (IJAG)• Adapts ink jet printer technology forthe production of well controlled andwell characterized aerosols• Three components:• Dispenser• Controller• ComputerHigh-speed images of particleejection (in air) by IJAG• Left to right = time (frames)• Top to bottom = distance
Initial Microorganisms Tested:• 4 organisms tested using a single particle test method• Bacillus Subtilis (Bs), vegetative form• Bacillus Globigii (Bg), spore form, washed• Bacillus Globigii (Bg), spore form, unwashed• Bacillus Thuringiensis (Bt), spore form, washed• Supplemental testing of 4 organisms using the traditionalbio-aerosol test method (high concentration aerosol challenge)• Staphylococcus epidermidis• Bacillus Thuringiensis• Aspergillus Niger• Yeast
Page 1 and 2: BioLaz Real Time MicrobialMonitorin
Page 3 and 4: Who We Are:• Particle Measuring S
Page 6 and 7: Microbiological MonitoringToday….
Page 8 and 9: Typical active air sampling -portab
Page 10 and 11: Real Time Microbial Monitoring
Page 13 and 14: Limitations of Impactiontechnologie
Page 15 and 16: Rapid Microbial Methods
Page 17 and 18: Cell Structure• All living cells
Page 19 and 20: Optical Fundamentals• The sample
Page 21 and 22: Data Output - 4 channels• Small P
Page 23 and 24: USP / EP Validation
Page 25 and 26: USP and EP 5.1.6Not requiredRequir
Page 27: Validation Test Setup
Page 31 and 32: Test Results Summary (concentration
Page 33 and 34: Example of Individual Bs TestCultur
Page 35 and 36: Bs Linearity
Page 37 and 38: Initial EP /USP ValidationConclusio
Page 39 and 40: Can common disinfectants /cleaning
Page 41 and 42: Shield Medicare BiocidesDate Descri
Page 43 and 44: Biocide testing:• Nebulized Bioci
Page 45 and 46: Our Approach• Step 1: - Can we va
Page 47 and 48: System Integration• Biolaz is not
Page 49 and 50: Installation QualificationProbe & T
Page 51 and 52: Performance Qualification• Verify
Page 53 and 54: Incorporation into EnvironmentalMon
Page 55 and 56: Monitoring Applications• Filling
Page 57 and 58: BioLaz Benefits• Faster batch rel
Page 59 and 60: Our Approach• Step 1: - Can we va
Page 61 and 62: 0:00:070:34:271:08:481:43:112:17:31
Page 63 and 64: 00.511.522.50:00:020:32:561:05:461:
Page 65 and 66: 0:00:010:31:211:02:421:34:022:05:23
Page 67 and 68: BIOLAZGRADE B IN OPERATION00.511.52
Page 69 and 70: BIOLAZ evaluationSummary data09 dec
Page 71 and 72: Calibration
Page 73 and 74: Sensor CalibrationThe software auto
Page 75 and 76: BioLaz Summary• Real-time, contin
Page 77: Questions?

Introducing BioLaz - CPAC

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