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Quaternium-15 contact allergy. DermNet NZ

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<strong>Quaternium</strong>-<strong>15</strong> <strong>contact</strong> <strong>allergy</strong>. <strong>DermNet</strong> <strong>NZ</strong>12/24/2007 06:45 PM<strong>DermNet</strong> <strong>NZ</strong>Authoritative facts about the skin from the New Zealand Dermatological Society Incorporated.Home | Eczema, dermatitis and allergiesAllergy to quaternium-<strong>15</strong>What is quaternium-<strong>15</strong> and where is it found?<strong>Quaternium</strong>-<strong>15</strong> is a formaldehyde-releasing preservative. It is used in many cosmetics and pharmaceuticalpreparations. It is also used as a preservative in many commercial and industrial products. The table below showssome of the products that may contain quaternium-<strong>15</strong>.Products containing quaternium-<strong>15</strong>CosmeticsSelf-hygiene/pharmaceutical products Commercial/industrialproductsFoundations, powders, concealersEye makeup (liners, shadows,mascara)Facial makeup (blushes)BronzesMakeup removersShampoosSoapsMoisturizing lotions and creamsShaving productsBody powdersSunscreensCleansers and other skin careproductsDisinfectantsAdhesivesFloor wax and polishPaper and paperboardWater-based inksLatex paintsIndustrial cutting fluidLaundry starchJoint cementPrinting pastesWhat are the reactions to quaternium-<strong>15</strong> <strong>allergy</strong>?Individuals reacting to quaternium-<strong>15</strong> may be either sensitive to formaldehyde or have a specific sensitivity.Typical allergic <strong>contact</strong> dermatitis reactions may occur from either of these sensitivity types.Positive patch teststo quaternium <strong>15</strong>Hand dermatititis due toquaternium-<strong>15</strong> in a moisturiserFacial dermatitis due to moisturiserAm I allergic to quaternium-<strong>15</strong>?<strong>Quaternium</strong>-<strong>15</strong> <strong>allergy</strong> is diagnosed from the clinical history and by performing special <strong>allergy</strong> tests, i.e. patchtests. Patch testing with 1% quaternium-<strong>15</strong> in petrolatum is used.http://www.dermnetnz.org/dermatitis/quaternium-<strong>allergy</strong>.htmlPage 1 of 4


<strong>Quaternium</strong>-<strong>15</strong> <strong>contact</strong> <strong>allergy</strong>. <strong>DermNet</strong> <strong>NZ</strong>12/24/2007 06:45 PMAzonium-adamantane chloridN-(3-chloroallyl) hexaminium chlorideChloroallyl methenamine chloride1-(3-chloroally)-3,5,7 triaza-1-azoniaadamantane chlorideMethanamine-3-chloroallylochlorideHexamethylenetetramineDowicil®75, Dowicil®100, Dowicil®200Avoid all of these. At work, request a material safety data sheet to help identify potential sources of exposure.Further informationFormula: C9H16Cl2N4CAS number: 51229-78-8Cross reactions: formaldehyde, formaldehyde-releasing preservativesSensitiser: formaldehydePatch Test: 1% quaternium-<strong>15</strong> in petrolatumSources of Exposure to <strong>Quaternium</strong>-<strong>15</strong>Adhesives and gluesCosmetics and toiletriesCutting fluidsDisinfectants and cleaning agentsLatex paintsMedications such as creams and lotionsPaper productsPolishesPrinting/etching materialsReferenceBook: Fisher's Contact Dermatitis. Ed Rietschel RL, Fowler JF. Lippincott Williams & Wilkins 2001Related informationOn <strong>DermNet</strong> <strong>NZ</strong>:DermatitisAllergic <strong>contact</strong> dermatitisPatch testingOther websites:T.R.U.E. Tests: vontact <strong>allergy</strong> to quaternium-<strong>15</strong>Allergic <strong>contact</strong> dermatitis – emedicine dermatology, the online textbookBooks:See the <strong>DermNet</strong> <strong>NZ</strong> bookstoreAuthor: Vanessa Ngan, staff writer<strong>DermNet</strong> does not provide an on-line consultation service.If you have any concerns with your skin or its treatment, see a dermatologist for advice.http://www.dermnetnz.org/dermatitis/quaternium-<strong>allergy</strong>.htmlPage 3 of 4


<strong>Quaternium</strong>-<strong>15</strong> <strong>contact</strong> <strong>allergy</strong>. <strong>DermNet</strong> <strong>NZ</strong>12/24/2007 06:45 PMCreated 2002. Last updated 24 Feb 2007. © 2007 <strong>NZ</strong>DS. Disclaimer.http://www.dermnetnz.org/dermatitis/quaternium-<strong>allergy</strong>.htmlPage 4 of 4

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