Program and Abstract Book - 19th International C. elegans Meeting

PLENARY, PARALLEL AND WORKSHOP LISTINGSFriday, June 28 9:00 AM–12:00 NOONAckerman Grand BallroomPhysiology II: Aging and Stress IIChairs: Elke Neumann-Haefelin, Freiburg University, Germany andArjumand Ghazi, University of Pittsburgh School of Medicine, USA78- 9:00 Discovering Conserved Mechanisms of Protection againstIschemia-reperfusion Injury Using a Novel C. elegans Behavioral Model.Dengke K. MA, Bob Horvitz.79- 9:12 Apoptotic hyperfunction causes gonadal atrophy in aging C.elegans. Yila de la Guardia, Ann Gilliat, Josephine Hellberg, DavidGems.80- 9:24 Molecular Outsourcing: Reproductive Signals Deploy NHR-49/PPARα to Reorganize Lipid Homeostasis and Alter Lifespan. RameshRatnappan, Jordan Ward, Francis RG Amrit, Hasreet Gill, Kyle Holden,Keith Yamamoto, Arjumand Ghazi.81- 9:36 Serotonergic signaling modulates the heat shock response inC. elegans. Veena Prahlad, Richard Morimoto.82- 9:48 The conserved SKN-1/Nrf2 stress response pathway regulatessynaptic function in Caenorhabditis elegans. Trisha Staab, TrevorGriffen, Connor Corcoran, Oleg Evgrafov, James Knowles, DerekSieburth.83- 10:00 Worms That Exercise Age Better. Daniel Burke, Mary AnneRoyal, Leo Gefter, Christina Chang, Monica Driscoll.10:12 - Break84- 10:36 Perturbations of Glycolytic Flux Differentially ImpactHealthspan via the Insulin Signaling and Dietary Restriction Pathways.Brian Onken, Monica Driscoll.85- 10:48 Regulation of C. elegans Reproductive Aging by a NovelGene-Environment Signaling Mechanism. Jessica Sowa, Meng Wang.86- 11:00 Molecular determinants of longevity in C. elegans and therelationship between lifespan, “health span”, and the rate of aging.Zachary Pincus, Frank Slack.87- 11:12 The conserved PBAF nucleosome remodeling complexmediates the response to stress in C. elegans. Aleksandra Kuzmanov,Evguenia Karina, Natalia Kirienko, David Fay.88- 11:24 The tune of Insulin/IGF-1 signaling pathway set by lincRNAs.Pengpeng Liu, M. Liu, L. Zhang, Z. Yang, K. Xiong, W. Dong, W. Zhang, Z.Zhu, Q. Fan, D. Liu.89- 11:36 Mitochondrial ROS promote longevity and innate immunityvia a feedback loop involving HIF-1 and AMPK. Ara B. Hwang, Eun-ARyu, Murat Artan, William Mair, Seung-Jae Lee.90- 11:48 How to live without water: Molecular strategies of the dauerlarva to survive extreme desiccation. Cihan Erkut, S. Penkov, S. Boland,A. Vasilj, H. Khesbak, Daniela Vorkel, B. Habermann, Jean-MarcVerbavatz, K. Fahmy, A. Shevchenko, T. V. Kurzchalia.Friday, June 28 9:00 AM–12:00 NOONBradley International BallroomGene Expression I: RNA Interference and Small RNAsChairs: John Murray, University of Pennsylvania, USA and JulieClaycomb, University of Toronto, Canada91- 9:00 Heterochromatin organization through development:regulated anchorage by H3K9 methylation and a novel chromodomainprotein. Susan M. Gasser, B. Towbin, A. Gonzalez, P. Zeller, V. Kalck.92- 9:12 Identification of small RNA pathway genes using patterns ofphylogenetic conservation and divergence. Yuval Tabach, A. Billi, G.Hayes, M. Newman, O. Zuk, H. Gabel, R. Kamath, B. Chapman, S. Garcia,M. Borowsky, J. Kim, G. Ruvkun.93- 9:24 The CSR-1 22G-RNA pathway modulates histone H3modifications associated with euchromatin. Christopher J. Wedeles,Julie M. Claycomb.94- 9:36 Positive regulation of Pol II transcription by CSR-1 RNAipathway in C. elegans. Germano Cecere, R. Sachidanandam, S. Hoersh,A. Grishok.95- 9:48 Characterization of the AGO protein VSR-1 in small RNAmediatedgene silencing pathways in the worm. Monica Z. Wu, Julie M.Claycomb.96- 10:00 Involvement of C. elegans let-7-Family developmental timingmicroRNAs in bacterial pathogen response. Zhiji Ren, Victor Ambros.10:12 - Break97- 10:36 In vivo quantitative analysis of the heterochronic pathwayreveals extensive target specificity of individual let-7 miRNA familymembers. Matyas Ecsedi, Helge Grosshans.98- 10:48 MUT-14 and SMUT-1 are redundantly required for germlineRNAi and endogenous siRNA production. Carolyn M. Phillips, Taiowa A.Montgomery, Peter C. Breen, Gary Ruvkun.99- 11:00 The essential CHORD protein CHP-1 functions in small RNApathways in C. elegans. Wendy X. Cao, Julie M. Claycomb.100- 11:12 Periodic A/T rich DNA structures promote germlineexpression. C. Frokjaer-Jensen, M. W. Davis, E. M. Jorgensen.101- 11:24 The period protein homolog LIN-42 negatively regulatesmicroRNA biogenesis in C. elegans. Priscilla M. Van Wynsberghe, E. F.Finnegan, T. J. Stark, Evan P. Angelus, K. Homan, G. W. Yeo, Amy E.Pasquinelli.102- 11:36 Arginine methylation is required for piRNA mediated genesilencing in Caenorhabditis elegans. Alexandra Sapetschnig, PeterSarkies, Eric Miska.103- 11:48 ALG-3/4 acts through the CSR-1 pathway to promotespermiogenic gene expression and to provide a paternally inheritedmemory of past gene expression. Colin Conine, James Moresco, JohnYates, Craig Mello.16