含簽名及附件-簡式 - 海洋生物科技暨資源學系- 國立中山大學

海洋生物科技暨資源學系一 ○○ 學年度第八次系務會議記錄一、時間 : 一 ○ 一年四月十六日 ( 星期一 ) 中午 12:00二、三、四、地點 : 海資館 2014 室召集人 : 林全信主任出席人員 : 許志宏、李玉玲、蔡錦玲、羅文增、徐基新、蕭炎宏、溫志宏、邱素芬、廖志中五、主席報告 :1. 本系 101 學年度博士班招生小組委員名單報告。2. 陳一鳴老師榮譽退休案報告。六、討論事項 :1. 案由 :2.3.決議 :組成系主任遴選委員會 ( 需投票 )。將選票發給本系講師以上所有教師 , 針對本系系務會議的成員最多可投同意票七票 , 投票截止日期為 4 月 23 日下午 5 點。開票後票數統計結果詳如附件一 , 遴選委員會成員為許志宏、王維賢、羅文增、徐基新、溫志宏、邱素芬、廖志中。案由 : 101 學年度校外合聘、兼任教師續聘案 ( 需投票 )。決議 :將選票發給本系講師以上所有教師 , 針對 101 學年度五位校外合聘教師及兼任教師投同意票 , 投票截止日期為 4 月 20 日中午 12 點。開票後票數統計結果詳如附件二 , 通過張芳榮、陳啟祥、宋秉鈞、楊生湳、陳武福等五位校外合聘教師續聘案 , 且通過方力行、吳永昌、陳一鳴等三位兼任教師之續聘案 , 將資料送交本系教評會審議。案由 : 本系優秀畢業生代表 ( 需填評分表 )。1

4.決議 :依據「國立中山大學海洋生物科技暨資源學系優秀畢業生評分原則」設計評分表 , 請本系教師針對四位候選學生評分 , 並請系主任與參加活動學生的指導老師評分後 , 截止日期為 4 月 23 日下午5 點。統計結果如附件三 , 由陳宜暄同學成為本系優秀畢業生代表。案由 : 新聘教師應徵狀況。決議 :新聘教師應徵者已整理表列如附件四 , 並以 e mail寄給每位老師參考 , 請各位老師連上 ftp 即可看到每位應徵者的詳細資料 , 並請領域相關之老師針對應徵者介紹討論。七、臨時動議 :1. 案由 :決議 :2. 案由 :決議 :提案一 : 本棟 4 樓廢氣排放系統提案。1. 本棟 4 樓廢氣排放系統依照環保方式處理、施工。2. 施工前 , 勿使用相關系統之儀器。3. 施工完成時 , 請蔡錦玲老師確認。如附件五。提案一 : 本系「五學年學、碩士學位」辦法修正提案。1. 第二條錄取名額改為八名。2. 第四條甄選辦法 : 資料審查的第一款在該系前五學期之平均成績改為班上前 50%。詳如附件六。2

附件二 :2012 New Faculty(101.04.16 更正 ):No. Applicants (tobe)Age:01 劉建宏Chien-Hung Liu( 助理教授 )Age: 1979Ph.D. (year) Teaching Courses Research goals (SCI)(year)國立成功大學化學工程所(2008.06)可開設課程 :有機化學化工反應工程化工熱力學生化工程酵素及發酵工程生物化學酵素固定化、發酵工程、菌種篩選、酵素動力學榮譽事蹟 :2006 廢水研討會優秀論文獎成大化工獎學金(2003/ 09 至2006/06)2010 台灣化學工程學會傑出論文獎First author:7 (2009 年以後 3 篇 )1. Liu C. H., C. C. Huang, Y. W. Wang, J. S. Chang*(2012) Optimizing lipase production from fromBurkholderia sp. J. Chin. Inst. Chem. Eng.(Accepted). [SCI]2. Liu C. H., C. Y. Chen, Y. W. Wang, J. S. Chang*.(2011) Fermentative Production of Lipase fromIndigenous Burkholderia sp. C20. Biochem. Eng.J. 58-59, p. 96-102. [SCI]3. Liu C. H., Y. H. Lin, C. Y. Chen, and J. S. Chang*.(2009) Characterization of Burkholderia lipaseimmobilized on celite carriers. J. Chin. Inst. Chem.Eng. 40, p. 359-363. [SCI]4. Liu C. H. and J. S. Chang*. (2008) Lipolyticactivity of suspended and membrane immobilizedlipase originating from indigenous Burkholderiasp. C20. Bioresour. Technol. 99, p. 1616-1622.[SCI]5. Liu C. H., J. Y. Wu, and J. S. Chang*. (2008)Diffusion characteristics and controlled release ofbacterial fertilizers from modified calcium alginatecapsules. Bioresour. Technol. 99, p. 1904-1910.[SCI]6. Chen C. Y., W. B. Lu, C. H. Liu, and J. S. Chang*(2008) Improved phototrophic H2 production withRhodopseudomonas palustris WP3-5 using acetateand butyrate as dual carbon substrates. Bioresour.Technol. 99, p. 3609-3616. [SCI]7. Liu C. H., W. M. Chen, and J. S. Chang*. (2007)Methods for rapid screening and isolation ofbacteria producing acidic lipase: feasibility studiesand novel activity assay protocols. World. J.Microbiol. Biotechnol. 23, 633-640. [SCI]8. Liu C. H., W. B. Lu, J. S. Chang*. (2006)Optimizing lipase production of Burkholderia sp.by response surface methodology. ProcessBiochem. 41, 1940-1944. [SCI]ExperienceCurrent國立成功大學化工系博士後研究員(2011/ 05至今 )OthersGrantsNationalityTaiwan

02 鄭再宏( 助理教授 )Age: 1974國立中興大學生物科技學研究所(2004)已開過之課程 :1. 醫學分子診斷學2. 醫用微生物免疫學3. 生物產業概論4. 專題討論未來可再開設課程 :新藥開發與分析海洋病毒學生物產業概論核酸學轉譯醫學分子診斷1. 新藥開發與分析2. 生物化學3. 遺傳學4. 生物技術學5. 細胞與分子生物技術學6. 微生物免疫學7. 分子病毒學8. 核酸學9. 膜體蛋白學10. 蛋白質體學11. 遺傳疾病診斷學First author:3 (2009 年以後 1 篇 )1. Cheng JH, YY Lien, MS Lee, HJ Chen, WH Su,MS Lee. Identification of NLS and NES motif ofVP2 from Chicken Anemia Virus and Interactionwith Mini-Chromosome Maintenance Protein 3.BMC Veterinary Research. 2012, 8:15. (7February 2012) (SCI; Impact factor: 2.37,Veterinary Sciences, Rank: 8/145, 5.4%)2. Chiu WH, Luo SJ, Chen CL, Cheng JH, Hsieh CY,Wang CY, Huang WC, Su WC, Lin CF. Vincaalkaloids cause aberrant ROS-mediated JNKactivation, Mcl-1 downregulation, DNA damage,mitochondrial dysfunction, and apoptosis in lungadenocarcinoma cells. Biochem Pharmacol 2012Jan 20. [Epub ahead of print] (SCI; Impactfactor: 4.889, Pharmacology & Pharmacy,Rank: 20/252, 7.9%)3. Chung KM, Huang CH, Cheng JH, Tsai CH, SuenCS, Hwang MJ, Chen X. Proline inTransmembrane Domain of Type II ProteinDPP-IV Governs Its Translocation Behaviorthrough Endoplasmic Reticulum. Biochemistry2011 Aug 23. (SCI; Impact factor: 3.226,Biochemistry & Molecular Biology, Rank:120/286, 41.9%)4. K M Chung, Cheng JH*, C S Suen, Y R Chen, C YChou, H P Chang, G G Chang, Andrew H J Wang,M J Hwang, X Chen. The DimericTransmembrane Domain of Prolyl Dipeptidase高雄醫學大學醫學研究所博士後研究員 (2012-Present)Taiwan

DPP-IV Contributes to its Quaternary Structureand Enzymatic Activities. (Accepted from ProteinScience, 2010) *Equal contribution (SCI;Impact factor: 2.74, Biochemistry & MolecularBiology, Rank: 147/286, 51.4%)5. Yeh TK, Tsai TY, Hsu T, Cheng JH, Chen X, SongJS, Shy HS, Chiou MC, Chien CH, Tseng YJ,Huang CY, Yeh KC, Huang YL, Huang CH,Huang YW, Wang MH, Tang HK, Chao YS, ChenCT, Jiaang WT. (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl] -4-fluoro-pyrrolidine-2-carbonitrile: Apotent, selective, and orally bioavailabledipeptide-derived inhibitor of dipeptidyl peptidaseIV. Bioorg Med Chem Lett 2010 Jun15;20(12):3596-600. Epub 2010 May 17. (SCI;Impact factor: 2.661, CHEMISTRY,MEDICINAL, Rank: 19/54, 35.2%)6. Lin CH, Peng YH, Coumar MS, Chittimalla SK,Liao CC, Lyn PC, Huang CC, Lien TW, Lin WH,Hsu JT, Cheng JH, Chen X, Wu JS, Chao YS, LeeHJ, Juo CG, Wu SY, Hsieh HP. Design andstructural analysis of novel pharmacophores forpotent and selective peroxisomeproliferator-activated receptor gamma agonists. JMed Chem 2009 Apr 23;52(8):2618-22. (SCI;Impact factor: 5.207, CHEMISTRY,MEDICINAL, Rank: 3/54, 5.5%)7. Tsai TY, Hsu T, Chen CT, Cheng JH, Chiou MC,

Tseng YJ, Yeh TK, Huang CY, Yeh KC, HuangCH, Huang YW, Wu SH, Wang MH, Chen X,Chao YS and Jiaang WT Rational design andsynthesis of potent and long-lasting glutamicacid-based dipeptidyl peptidase IV inhibitors.Bioorg Med Chem Lett 2009 Apr1;19(7):1908-12. (SCI; Impact factor: 2.661,CHEMISTRY, MEDICINAL, Rank: 19/54,35.2%)8. Tsai TY, Hsu T, Chen CT ,Cheng JH, Yeh TK,Chen CT, Chen X, Huang CY, Chang CN, YehKC , Hsieh SH, Chien CH, Chien CH, ChangYW, , Huang CH, Huang YW, Hung CL, Wu SH,Wang MH, Chao YS, Jiaang WT* Noveltrans-2-aryl-cyclopropylamine analogues as potentand selective dipeptidyl peptidase IV inhibitors.Bioorg Med Chem 2009 Mar 15;17(6):2388-99.Epub 2009 Feb 20. (SCI; Impact factor: 2.978,CHEMISTRY, MEDICINAL, Rank: 15/54,27.8%)9. Coumar MS, Chang CN, Chen CT, Chen X, ChienCH, Tsai TY, Cheng JH, Wu HY, Han CH, WuSH, Huang YW, Hsu T, Hsu LJ, Chao YS, HsiehHP and Jiaang WT.3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3- methylbutyramide analogues as selectiveDPP-IV inhibitors for the treatment of type-IIdiabetes. Bioorganic & Medicinal ChemistryLetters 17 (2007) 1274–1279. (SCI; Impact

factor: 2.661, CHEMISTRY, MEDICINAL,Rank: 19/54, 35.2%)10.Lu IL, Lee SJ, Tsu H, Wu SY, Kao KH, Chien CH,Chang YY, Chen YS, Cheng JH, Chang CN,Chen TW, Chang SP, Chen X, and Jiaang WT.Glutamic acid analogues as potent dipeptidylpeptidase IV and 8 inhibitors. Bioorganic &Medicinal Chemistry Letters 15 (2005)3271–3275. (SCI; Impact factor: 2.661,CHEMISTRY, MEDICINAL, Rank: 19/54,35.2%)11.Cheng JH, Peng CW, Hsu YH, and Tsai CH. Thesynthesis of minus-strand RNA of bamboo mosaicpotexvirus initiates from multiple sites within thepoly (A) tail. J Virol 2002 Jun;76(12):6114-20.(SCI; Impact factor: 5.189, VIROLOGY, Rank:5/33, 15.2%)12.Cheng JH, Ding MP, Hsu YH, and Tsai CH. Thepartial purified RNA-dependent RNA polymerasesfrom bamboo mosaic potexvirus and potato virusX infected plants containing thetemplate-dependent activities. Virus Res 2001 Nov28;80(1-2):41-52. (SCI; Impact factor: 2.905,VIROLOGY, Rank: 14/33, 42.4%)13.Tsai CH, and Cheng JH. The preparation ofRNA-dependent RNA polymerase complex fromvirus infected plants. Proc Natl Sci Counc RepubChina B. 1998 Apr;22(2):83-90. (SCI)03 黃祥麟 Institute of 可開設課程 : 1. Ecology—life First author:7 (2009 年以後 6 篇 ) 2011 Taiwan

Shiang-LinHuang( 助理教授 )Age: 1980EcologyandEvolutionBiology,NationalTaiwanUniversity(2009.01)普通生物學普通動物學生態學海洋哺乳類鯨豚生態保育保育生物學生活史策略模式生物學history strategy2.Ecology—ecological modeling3. Conservationbiology—population viability analysis,minimum viablepopulation, marineprotected area,status assessment,risk assessment4.Zoology—marinemammalogy,branchiopod(crustacean) lifehistories1. Huang, Shiang-Lin, Ni, I-H., Chou, L.-S. 2008.Correlations in cetacean life history traits. The RafflesBulletin of Zoology Supplement No. 19: 285-292(SCI, IF=1.456, rank = 47/145=32.41%,NSC-95-2621-B-019-004)2. Huang, Shiang-Lin, Chou, L.-S., Ni, I-H. 2009Comparable length at weaning in cetaceans. MarineMammal Science. 25: 875-887 (SCI, IF=1.463, rank =46/145=31.72%, NSC 97-2311-B-019-003, NSC95-2621-B-019-004)引用次數 : 23. Huang, Shiang-Lin, Chou, L.-S., Ni, I-H. 2010Implication of life history strategies for prenatalinvestment in cetaceans. Marine Mammal Science27(1): 182-194 DOI:10.1111/j.1748-7692.2010.00392.x (SCI, IF=1.463,rank = 46/145=31.72%, NSC 97-2311-B-019-003)引用次數 : 1InvitedVisitingScholar,Institute ofHydrobiology, ChineseAcademy ofSciences,Wuhan430072,China榮譽事蹟 :97 年(97.1.1~97.12.31)Annual AcademicPoster ContestAward, AnnualMeeting ofFishery Society ofTaiwan, December15-16, 2007.Kaohsiung,Taiwan.4. Huang, Shiang-Lin, Wang, C.-C., Huang, W.-P.,Chou, L.-S. 2010. Indeterminate growth of fairyshrimps, Branchinella kugenumaensis (Crustacea:branchiopoda), in an unpredictable ephemeral pool.Journal of Crustacean Biology 30(3): 366-372, DOI:10.1651/09-3235.1 (SCI, IF = 1.115, rank = 52/92 =56.52%)5. Huang, Shiang-Lin, Chun-Chieh Wang, Wan-PingHuang, Lien-Siang Chou. 2011. The reproductivepotential of fairy shrimp, Branchinella(Branchinellites) kugenumaensis, in an unpredictable

ephemeral pool. Journal of Crustacean Biology 31(2):254-259 (SCI, IF = 1.115, rank = 52/92 = 56.52%)6. Ming-Chih Wang, Kwang-Tsao Shao, Shiang-LinHuang, Lien-Siang Chou. 2011 Food partitioningamong three sympatric odontocetes (Grampus griseus,Lagenodelphis hosei and Stenella attenuata). MarineMammal Science DOI:10.1111/j.1748-7692.2011.00501.x. (SCI, IF=1.463,rank = 46/145=31.72%)7. Wang, Chun-Chieh, Huang, Shiang-Lin, Huang,Wan-Ping, Chou, Lien-Siang. 2012. 4 Spatial nichedifferentiation of sympatric branchiopoda in a highlyunpredictable ephemeral pool. Journal of CrustaceanBiology 32(1): in press (accepted in 2011/05/26)(SCI, IF = 1.115, rank = 52/92 = 56.52%).8. Huang, Shiang-Lin, Leszek Karczmarski, JialinChen, Ruilian Zhou, Wenzhi Lin, Haifei Zhang,Haiyan Li, Yu-Pin Wu. 2012. Demography andpopulation trend of the largest population ofIndo-Pacific humpback dolphin (Sousa chinensis).Biological Conservation: in press, DOI:10.1016/j.biocon.2012.01.004 (accepted in2012/01/04, SCI, IF = 3.498, rank = 6/33 = 18.2%)9. Huang, Shiang-Lin, Yu-Jiang Hao, Zhi-Gang Mei,Samuel T. Turvey, Ding-Wang. 2012 Commonpattern of population decline for freshwater cetaceanspecies in deteriorating habitats. Freshwater Biology,in press. (accepted in 2012/02/21, SCI, IF = 3.082,rank = 7/92 = 7.61%)

. papers submitted/to be submitted1. Zhi-Gang Mei, Shiang-Lin Huang, Yu-Jiang Hao,Samuel T. Turvey, Ding-Wang, Wei-Ming Gong.Accelerating population decline of Yangtze finlessporpoise. (submitted to Biological Conservation,minor revision)2. Huang, Shiang-Lin, Yu-Jiang Hao, I-Hsun Ni,Ding Wang. Life history divergence of finlessporpoise, Neophocaena spp., in Chinese waters. (inpreparation)3. Huang, Shiang-Lin, Yu-Jiang Hao, Zhi-Gang Mei,Samuel T. Turvey, Ding-Wang. Threshold ofpopulation persistence for Yangtze finless porpoise.(in preparation)4. Huang, Shiang-Lin, (authors to be invited), LeszekKarczmarski*. Threshold of population persistence forAsian coastal dolphin species. (in preparation)5. Huang, Shiang-Lin, (authors to be invited), LeszekKarczmarski*. Vulnerability and sensitivity ofultimate survival for the Indo-Pacific humpback04 張淑微(Chang,Shu-Wei)( 助理教授 )Age: 1976國立海洋大學生物科技研究所 ,(2006)dolphin. (inpreparation)已開設過之課程 : 學術專長 : First author:13 (2009 年以後 4 篇 )大葉大學藥用植物1. 普通生物學 ( 含實 1. 機 2. 能生性特用化學 3. 食 1. 品 Shieh, 生物化 C.-J.*; 學 Chang, 4. S.-W. 食品微 2001 生物 Optimized 學 5. 酵素學與保健學系 -- 助理驗 )品物生化物製程開發 enzymatic synthesis of hexyl acetate with lipase 教授2. 生物化學 ( 含實驗 ) 2. 酵學素 ( 含生物科技 IM77 from Mucor miehei. J. Agri. Food Chem. 49: (08/2009~迄今 )3. 食品生物化學 3. 藥實妝驗有 ) 效成分生 1203−1207. (IF=2.469)4. 食品微生物學合成技術 2. Chiang, W.-D., Chang, S.-W.; Shieh, C.-J.* 20035. 酵素學 4. 保健產品應用科 Study on the optimized lipase-catalyzed biosynthesis6. 生物產業科技特論技 7. 生 8. 計算機 of 概 cis-3-hexen-1-yl 論 9. acetate 生物統 in 計 n-hexane. 學 Process 10. 中醫保健美容學Taiwan

7. 生物科技研究法論 5. 生物質科能源 Biochem.38, 1193−1199. (IF=2.414)8. 計算機概論9. 生物統計學技研究法3. Yu, Z.-R., Chang, S.-W.,Wang, H.-Y.; Shieh, C.-J.*2003 Study on synthesis parameters of10. 中醫保健美容學11. 藥用植物商品行 12.lipase-catalyzed hexyl acetate in supercritical CO2 by13. 生物 response 科技與生 surface 命 methodology. 14. 普通化學 J. ( 含 Am. 實驗 Oil ) Chem. 15. 特用油脂學銷管理學化粧倫理 Soc. 80, 139−144. (IF=1.803)12. 化粧品行銷管理學13. 生物科技與生命倫理14. 普通化學 ( 含實驗 )15. 特用油脂學16. 生物催化特論品行銷管理學4. Chang, S.-W.; Shaw, J.-F.; Shieh, C.-J.* 2003Optimization of enzymatically prepared hexylbutyrate by Lipozyme IM-77. Food Technol.Biotechnol. 41, 237−242. (IF=0.976)5. Liao, H.-F; Tsai, W.-C.; Chang, S.-W.; Shieh, C.-J.*2003 Application of solvent engineering to optimizelipase-catalyzed 1,3-diacylglycerols by mixtureresponse surface methodology. Biotechnol. Lett. 25,17. 脂質生物科技 17. 脂質生物科技特 1857−1861. 18. 高等 (IF=1.636) 特化研究 19. 脂解酵素特論特論18. 高等特化研究法19. 脂解酵素特論6. Shaw, J.-F., Chang, S.-W., Liao, H.-F.; Shieh, C.-J.*2003 Lipase-catalyzed biosynthesis of hexyl butyrateby direct esterification: Optimization by responsesurface methodology. J. Sci. Food Agri. 83,1525−1530. (IF=1.386)7. Chang, S.-W.; Shieh, C.-J.; Lee, G.-C.; Shaw, J.-F.*2005 Multiple mutagenesis of the Candida rugosaLIP1 gene and optimum production of recombinantLIP1 expressed in Pichia pastrois. Appl. Microbiol.Biotechnol. 67, 215−224. (IF=2.896)8. Chang, S.-W.; Shaw, J.-F.; Yang, K.-H.; Shih, I.-L.;Hsieh, C.-H.; Shieh, C.-J.* 2005 Optimallipase-catalysed hexyl laurate. Green Chem. 7,547—551. (IF=5.836)

9. Chang, S. W.; Lee, G. C.; Shaw, J. F.* 2006 Codonoptimization of Candida rugosa lip1 gene forimproving expression in Pichia pastoris andbiochemical characterization of the purifiedrecombinant LIP1 lipase. J. Agric. Food Chem. 54,815−822. (IF=2.469)10. Chang, S.-W.; Shieh, C.-J.; Lee, G.-C.; Akoh, C.-C.;Shaw, J.-F.* 2006 Optimized growth kinetics ofPichia pastoris and recombinant Candida rugosaLIP1 production by RSM. J. Mol. Microbiol.Biotechnol. 11, 28−40. (IF=2.660)11. Chang, S.-W.; Lee, G.-C.; Shaw, J.-F. 2006Efficient production of active recombinant Candidarugosa LIP3 lipase in Pichia pastoris andbiochemical characterization of the purified enzyme.J. Agric. Food Chem. 54, 5831−5838. (IF=2.469)12. Srivastava, A.; Akoh, C. C.; Chang, S.-W.; Lee,G.-C.; Shaw, J.-F. 2006 Candida rugosa lipaseLIP1-catalyzed transesterification to produce humanmilk fat substitute. J. Agric. Food Chem. 54,5175−5181. (IF=2.469)13. Chang, S.-W.; Shaw, J.-F.; Hsieh,C.-H.;Shieh,C.-J.* 2006. Optimal formation of hexyl laurate byLipozyme IM-77 in solvent-free system. J. Agric.Food Chem. 54, 7125−7129. (IF=2.469)14. Chang, S.-F.; Chang, S.-W.; Yen, Y.-H.; Shieh,C.-J.* 2007. Optimum immobilization of Candidarugosa lipase on celite by RSM. Appl. Clay Sci. 37,67−73. (SCI). (IF=2.784)

15. Chang, S.-W.; Shaw, J.-F.; Yang,C.-K.;Shieh, C.-J.*2007. Optimal continuous biosynthesis of hexyllaurate by a packed-bed bioreactor. ProcessBiochem. 42, 1362−1366. (SCI) (IF=2.444)16. Chang, S.-W.; Shaw, J.-F.; Yang, K.-H.;Chang,S.-F.; Shieh, C.-J.* 2008. Studies of optimumconditions for covalent immobilization of Candidarugosa lipase on poly(γ-glutamic acid) by RSM.Bioresource Technol. 99, 2800−2805 (SCI).(IF=4.253)17. Akoh, C. C.; Chang, S.-W.; Lee, G.-C.; Shaw, J.-F.*2007. Enzymatic approach to biodiesel production. J.Agric. Food Chem. 55, 8995−9005 (SCI). (IF=2.469)18. Lumor, S. E.; Jones, K. C.; Ashby, R.; Strahan, G.D.; Kim, B. H.; Lee, G.-C.; Shaw, J.-F.; Kays, S. E. ;Chang, S.-W.; Foglia, T. A.; Akoh, C. C.* 2007.Synthesis and characterization of canola oil-stearicacid-based trans-free structured lipids for possiblemargarine application. J. Agric. Food Chem.55,10692−10702(SCI).(IF=2.469)19.Shaw, J.-F.;Chang, S.-W.; Lin, S.-C.;Wu, T.-T.; Ju,H.-Y.; Akoh, C. C.;Chang, R.-H.Shieh, C.-J.* 2008.Continuous enzymatic synthesis of biodiesel withNovozym 435. Energ. Fuel.22, 840−844(SCI).(IF=2.319)20.Akoh, C.C.;Chang, S.-W.; Lee, G.-C.; Shaw, J.-F. *2008. Biocatalysis for theproductionofindustrialproducts and functionalfoods fromriceand otheragricultural produce.J. Agric. Food Chem.

56, 10445−10451 (SCI).(IF=2.469)21.Chang, S.-W.; Yang, C.-J.; Chen, F.-Y.; Akoh, C.C.; Shieh, C.-J.* 2009. Optimized synthesisoflipase-catalyzed L-ascorbyl laurate by Novozym435. J. Mol. Catal. B, Enzym.56,7−12(SCI).(IF=2.015)22.Chang, S.-W.; Shaw, J.-F.2009.Biocatalysis for theProduction of Carbohydrate Esters. NewBiotechnol.26, 109−116 (SCI).(IF=2.000)23.Chou,H.-H.;Chang,S.-W.*Lee,G.-C.;Chen,Y.-S.;Yeh,T.;Akoh,C.C.;Shaw, J.-F.* 2010.Site-directedmutagenesis improves thethermostability ofarecombinantPicrophilus torridustrehalose synthaseand efficiency for theproduction oftrehalosefromsweetpotato starch. Food Chem. 119, 1017-1022(SCI).(IF=3.146)24.Chang, S.-W.; Chang, W.-H.; Lee, M.-R.; Yang,T.-J.; Yu, N.-Y.; Chen, C.-S.*; Shaw,J.-F.*2010.Simultaneousproduction oftrehalose,bioethanol, and high-protein product fromrice by anenzymaticprocess. J. Agric. Food Chem.58,2908-2914(SCI).(IF=2.469)25.Chang, S.-W.*; Li, C.-F.; Lee, G.-C.; Yeh, T.; Shaw,J.-F.*2011.Engineering the expression andbiochemical characteristics of recombinantCandidarugosaLIP2 lipase by removing theadditionalN-terminalpeptideand regional codonoptimization. J. Agric. Food Chem.59,6710-6719.(IF=2.469)

05 AndersonB.Mayfield,Ph.D.“ 安德森 ”( 助理教授 )Age: ?Universityof Hawaii,Manoa,Department ofZoology,Honolulu,Hawaii.Ph.D.,Zoology.(Fall 2009)已開設過之課程 :1. The molecularbiology ofcnidarians:fundamentals andtechniques2. Advancedpractices inmarine molecularbiology3. BiochemicalAdaptation4. CnidarianphysiologyMy research interestscenter around twopredominant themes,both of which involvephotosyntheticendosymbiosesbetween anthozoans(corals and seaanemones) anddinoflagellates of thegenusSymbiodinium.First author:4 (2009 年以後 3 篇 )1. Putnam HP, Mayfield AB, Fan TY, Chen CS,Gates RD (accepted) The physiological andsub-cellular impacts of global climate changeconditions on larvae of the reef-building coralPocillopora damicornis. Mar Biol2. Chen WNU, Kang HJ, Weis VM, Mayfield AB,Fang LS Chen CS (in press) Diel rhythmicity oflipid body formation in a coral-Symbiodiniumendosymbiosis. Coral Reefs. doi:10.1007/s00338- 011-0868-63. Mayfield AB, Wang LH, Tang PC, Hsiao YY,Fan TY, Tsai CL, Chen CS (2011) Assessing theimpacts of experimentally elevated temperatureNationalScienceFoundation(NSF)internationalpostdoctoralresearchfellowship(OISE-0852960),NMMBA,Checheng,Taiwan,postdoctoralresearcher,(Feb.2010-current.)USAon the biological composition and molecularchaperone gene expression of a reef coral. PLoSOne e26529.4. Peng SE, Chen WU, Chen HK, Lu CY,Mayfield AB, Fang LS, Chen CS (2011) Lipidbodies in coraldinoflagellate endosymbiosis:ultrastructural and proteomic analyses.Proteomics 17: 3540-55.5. Mayfield AB, Hsiao YY, Fan TY, Chen CS,Gates RD (2010) Evaluating the temporal stabilityof stress-activated protein kinase andcytoskeleton gene expression in the Pacific coralsPocillopora damicornis and Seriatopora hystrix. JExp Mar Biol Ecol 395: 215-222.6. Mayfield AB, Hirst MB, Gates RD (2009) Gene

expression normalization in a dual-compartmentSystem: a real-time PCR protocol for symbioticanthozoans. Molec Ecol Res 9: 462-470.7. Mayfield AB, Gates RD (2007)Osmoregulation in anthozoan-dinoflagellatesymbiosis. Comp Biochem Physiol A 147: 1-10.06 陳宣汶Chen,HsuanWien( 助理教授 )Age: ?台灣師範大學生命科學系(2010)已開設過之課程 :1. 海洋生態系概論2. 大洋與深海生態系3.Network Analysis4. 食物網 : 理論與分析海洋寄生蟲多樣性、疾病生態與演化、食物網分析、生態系模式First author:2 (2009 年以後 1 篇 )1. Chen H.‐W., K.‐T. Shao, C. W.‐J. Liu, W.‐H. Lin and,W.‐C. Liu. 2011. Reduction of networkrobustness by parasitism: fact and artifact.International Journal for Parasitology 41:627‐634. (IF=3.822, 4/32 in Parasitology)中央研究院生物多樣性研究中心博士後研究員(2011/7~ 至今Taiwan2. Liu, W.‐C., H.‐W. Chen*, F. Jordan, W.‐H. Lin and, C.W.‐J.Liu. 2010. Quantifying the interactionstructure and the topological importance ofspecies in food webs: A signed digraphapproach. Journal of Theoretical Biology 267:355‐362. (*corresponding author; IF=2.371,10/37 in Math. & Comput. Biology)3. Chen, H.‐W., W.‐C. Liu, A. D. J. Davis, F. Jordan, M.‐J. Hwang, and K.‐ T. Shao. 2008. Networkposition of hosts in food webs and their parasitediversity. Oikos 117: 1847‐1855. (IF: 3.393,33/129 in Ecology)4. Falcón‐Ordaz, J., H.‐W. Chen, and M. R.Lamothe‐Argumedo. 2006. A new species ofVexillata (Nematoda: Ornithostrongylidae)

parasite of Attwater’s pocket gopher from Texas.Journal of Parasitology 92: 595‐599. (IF: 1.208,21/32 in Parasitology)5. Zhu, G., and H.‐W. Chen. 2004. Monophyleticrelationship between severe acute respiratorysyndrome coronavirus and group 2coronaviruses. Journal of Infectious Diseases189: 1676‐1678. (IF=6.288, 5/58 in InfectiousDiseases)6. Dronen, N. O., and H.‐W. Chen. 2002.Endohelminths from little blue heron, Egrettacaurulea, from Texas Gulf Coast. ComparativeParasitology 69: 96‐99. (IF=0.869, 82/145 inZoology)07 ManoharanKaruppiahPillai( 助理教授 )Age: 1969NaturalProductsChemistry/PhytochemistryNationalUniversityofSingapore,Singapore(2006)Cytotoxic steroidsand terpenoids frommarine InvertebratesFirst author:7 (2009 年以後 4 篇 )1. Manoharan K Pillai., Benny T. K. H., Dai Wen Y.,Cycloartane type triterpenoids from the rhizomes ofPolygonum bistorta. Phytochemistry, 2005, 66,2304-2308.2. Manoharan K Pillai., Fan J. S., Benny T. K. H., DaiWen Y., Triterpenoids from Eugenia grandis.Magnetic Resonance in Chemistry, 2007, 45,279-281.3. Manoharan K Pillai., Dai Wen Y., Annie H., BennyT. K. H., Evaluation of Polygonum bistorta for2010-Current,Institute forResearch inMolecularMedicine(INFORMM)UniversityScienceMalaysia,MalaysiaIndiaanticancer potential using selected cancer cell lines.Medicinal Chemistry, 2007, 3, 121-126.4. Manoharan K Pillai et al., Solvent-free Knoevenagel

condensation over Co-hydroxyapatite. SyntheticCommunications, 2010, 40, 3710-3715.5. Manoharan K Pillai et al., Inhibitory effect ofethanolic and water extracts of two varieties ofginger on selected bacterial and fungal isolates.Pharmacologyonline, 2010, 3, 951-958.6. Manoharan K Pillai et al., Solvent-free Knoevenagelcondensation over Ir and Pt hydroxyapatites. InPress, 20117. Manoharan K Pillai et al., Evaluation of radicalscavenging activity of rhizome extracts of Alpiniagalanga and Zingiber officinale. Journal ofMedicinal Plants Research, 2011 (Accepted)08 顏孟畿Meng-ChiYen( 助理教授 )Age: 1978Ph.D., Theinstitute ofbasicmedicalscience,NationalChengKungUniversity(2009.6)已開設過之課程 :1. 生物化學與生物化學實驗2. 應用分子生物學3. 腫瘤生物學4. 專題討論5. 基因治療特論6. 癌症分子病理學1. Tumor biology2. Immunology3. Immunotherapyand DNA vaccine4. Biochemistry andmolecular biologyFirst author:3 (2009 年以後 1 篇 )1. Lin CC, Tu CF, Yen MC, Chen MC, Hsieh WJ, ChangWC, Chang WT, Lai MD. Inhibitor of Heat-shockProtein 90 Enhances the Antitumor Effect of DNAVaccine Targeting Clients of Heat-shock Protein. MolTher. 2007 Feb;15(2):404-10. (IF=7.149, 7/106 inMEDICINE, RESEARCH & EXPERIMENTALcategory) SCIAssistant Taiwanprofessor,Department ofBiochemistryand MolecularBiology,NationalCheng KungUniversity2. Lin CC, Yen MC, Lin CM, Huang SS, Yang HJ, ChowNH, Lai MD. Delivery of noncarrier naked DNA(2011.8~present)vaccine into the skin by supersonic flow induces apolarized T helper type 1 immune response to cancer. JGene Med. 2008 Jun;10(6):679-89. (IF=3.079, 32/106in MEDICINE, RESEARCH & EXPERIMENTAL

category) SCI3. Yen MC, Lin CC, Chen YL, Huang SS, Yang HJ, ChangCP, Lei HY, Lai MD. A Novel Cancer Therapy by SkinDelivery of Indoleamine 2,3-Dioxygenase siRNA ClinCancer Res. 2009 Jan 15;15(2):641-649. (IF=7.338,16/184 in ONCOLOGY category) SCI4. Lai MD, Yen MC, Lin CM, Tu CF, Wang CC, Lin PS,Huang HJ, Lin CC. The effects of DNA formulationand administration route on cancer therapeutic efficacywith xenogenic EGFR DNA vaccine in a lung canceranimal model. Genet Vaccines Ther. 2009 Jan 30;7:2.5. Lai MD, Chen CS, Yang CR, Yuan SY, Tsai JJ, Tu CF,Wang CC, Yen MC, Lin CC. An HDAC inhibitorenhances the antitumor activity of a CMVpromoter-driven DNA vaccine. Cancer Gene Ther.2010 Mar;17(3):203-11. (IF=3.744, 23/106 inMEDICINE, RESEARCH & EXPERIMENTALcategory) SCI6. Yang HJa, Yen MCa, Lin CC, Lin CM, Chen YL, WengTY, Huang TT, Lai MD. A Combination of metabolicenzyme inhibitor APO866 and immune adjuvantL-1-methyl tryptophan induces additive antitumoractivity. Exp Biol Med (Maywood). 2010Jul;235(7):869-76. (a equal contribution) (IF=2.954,33/106 in MEDICINE, RESEARCH &EXPERIMENTAL category) SCI7. Wang ST, Chang CC, Yen MC, Tu CF, Chu CL, Peng

YT, Chen DY, Lan JL, Lin CC. RNAinterference-mediated silencing of the Foxo3 in antigenpresenting cells as a strategy for enhancement of DNAvaccine potency. Gene Ther. 2011 Apr;18(4):372-83.(IF=4.538, 22/160 in BIOTECHNOLOGY & APPLIEDMICROBIOLOGY category) SCI8. Shan YS, Fang JH, Lai MD, Yen MC, Lin PW, Hsu HP,Lin CY, Chen YL. Establishment of an orthotopictransplantable gastric cancer animal model for studyingthe immunological effects of new cancer therapeuticmodules. Mol Carcinog. 2011 Oct: 50(10): 739-750.(IF=3.265, 63/184 in ONCOLOGY category) SCI9. Huang TTa, Yen MC a, Lin CC, Weng TY, Chen YL,Lin CM, Lai MD. Skin delivery of short hairpin RNAof indoleamine 2,3 dioxygenase induces anti-tumorimmunity against orthotopic and metastatic liver cancer.Cancer Sci. 2011 Dec;102(12):2214-2220. (a equalcontribution) (IF=3.864, 53/184 in ONCOLOGYcategory) SCI.09 曾宗德Tzong-DerTzeng( 教授 ?)Age: 1967國立台灣大學海洋研究所生物及漁業組博士(1998.06)擬開課名稱 :1、海洋無脊椎動物學2、水產資源學 ( 漁業生物學 )3、漁業資源評估學4、海洋生物學5、海洋生態學6、魚類生態學7、沿近海漁業學8、多變量統計學9、生物統計學10、族群遺傳學水產資源學 ( 漁業生物學 )、水產資源管理學、海洋生物生態學、族群遺傳學、生物地理學、解說教育、生態旅遊First author:12 (2009 年以後 4 篇 )— 已算入corresponding author 篇數* corresponding author, †authors contributed equally1. T-Y Chiang 1,†, T-D Tzeng 2,†, H-D Lin 3, C-J Cho1 and F-J Lin 1,* (2012) Isolation andCharacterization of Polymorphic MicrosatelliteLoci from Metapenaeopsis barbata UsingPCR-Based Isolation of Microsatellite Arrays(PIMA). Int. J. Mol. Sci. 13: 2763-2768. (SCI,2011.8~ 迄今樹德科技大學通識學院自然科學組及管理學院休閒事業管理學系Taiwan

impact factor: 2.279, ranking: 41/147)2. T-J Chu, D Wang, H-L Huang, F-J Lin, and T-DTzeng* (2012) Population Structure and HistoricalDemography of the Whiskered Velvet Shrimp(Metapenaeopsis barbata) off China and TaiwanInferred from the Mitochondrial Control Region.Zoological Studies, 51 (1): 99-107. (SCI, impactfactor: 1.046, ranking: 65/145)3. T-J Chu, H-L Haung, C-H Shih, F-J Lin and T-DTzeng* (2011) Population structure and expansionof kuruma shrimp (Penaeus japonicus) in theadjacent waters of Taiwan inferred from intronsequences. African Journal of Biotechnology,10(74): 16994-17009. (SCI, impact factor: 0.573,ranking: 137/160)4. T-J Chu, D Wang, H-L Haung, F-J Lin, C-MWang, C-H Shih, T-D Tzeng* (2011) Geneticvariations and expansion of whiskered velvetshrimp (Metapenaeopsis barbata) off China andTaiwan inferred from intron sequence.Biochemical Systematics and Ecology 39:520–525. (SCI, impact factor: 1.110, ranking:93/130)5. C-H Shih, H-L Haung, T-J Chu, Y-C Lee, C-MWang and T-D Tzeng* (2011) Genetic diversityand historical demography of kuruma shrimp(Penaeus japonicus) species complex off Chinabased on mitochondrial DNA analysis. AfricanJournal of Biotechnology ,10(7): 1065-1072.教授兼通識教育學院院長

(SCI, impact factor: 0.573, ranking: 137/160)6. Tzeng, T. D.*, D. Wang, H. L. Haung, and S. Y.Yeh. (2008). Population Structure in theSwordPrawn (Parapenaeopsis hardwickii) from the EastChina Sea and Taiwan Strait Inferred from IntronSequences. Journal of Crustacean Biology,28(2): 234-239. (SCI, impact factor: 1.115,ranking: 53/93)7. S. C. Chen, T. Y. Wang, T. D. Tzeng, C. Y. Wang,D. Wang* (2008). Evidence for Positive Selectionin the TLR9 Gene of Teleosts. Fish and ShelfishImmunology, 24: 234-242. (SCI, impact factor:3.044, ranking: 4/145)8. Tzeng, T. D.* (2007) Population Structure andHistorical Demography of the Spotted Mackerel(Scomber australasicus) off Taiwan Inferred fromMitochondrial Control Region Sequencing.Zoological Studies, 46(6): 656-663. (SCI, impactfactor: 1.046, ranking: 65/145)9. Tzeng, T. D.* (2007) Population Structure of theSword Prawn (Parapenaeopsis hardwickii)(Decapoda: Penaeidae) in the East China Sea andWaters Adjacent to Taiwan Inferred from theMitochondrial Control Region. ZoologicalStudies, 46(5): 561-568. (SCI,impact factor:1.046, ranking: 65/145)10. Lu, C. P., C. L. Chen, C. F. Hui, T. D. Tzeng andS. Y. Yeh* (2006) Population genetic structure ofthe swordfish, Xiphias gladius, in the Indian

Ocean and West Pacific inferred from thecomplete DNA sequence of the mitochondrialcontrol region. Zoological Studies, 45(2):269-279. (SCI, impact factor: 1.046, ranking:65/145)11. Tzeng, T. D.* (2004). Morphological variationbetween populations of spotted mackerel(Scomber australasicus) off Taiwan. FisheriesResearch, 68: 45-55. (SCI, impact factor: 1.531,ranking: 13/42)12. Tzeng, T. D.* (2004). Stock identification ofsword prawn (Parapenaeopsis hardwickii) in theEast China Sea and Taiwan Strait inferred bymorphometric variation. Fisheries Science, 70(5):758-764. (SCI, impact factor: 0.684, ranking:34/42)13. Tzeng, T. D.*, S. Y. Yeh and C. F. Hui (2004).Population structure of Kuruma shrimp (Penaeusjaponicus) from the East China Sea and theTaiwan Strait inferred by mitochondria DNAsequence. ICES Journal of Marine Science,61(6): 913-920. (SCI, impact factor: 1.920,ranking: 9/42)14. Tzeng, T. D. and S. Y. Yeh (2002). Multivariateallometric comparisons for kuruma shrimp(Penaeus japonicus) off Taiwan. FisheriesResearch, 68: 45-55. (SCI, impact factor: 1.531,ranking: 13/42)15. Tzeng, T. D., C. S. Chiu and S. Y. Yeh (2001)

Morphometric variation in red-spot prawn(Metapenaeopsis barbata) in different geographicwaters off Taiwan. Fisheries Research, 68: 45-55.10 Dr. ChiranjibChakraborty,M.Sc.,PhD( 副教授 )Age:1973Ph.D.VidyasagarUniversity,Midnapore, WestBengal,India.(PhDresearchwork hasbeencarried outinMarineAquariumandResearchCentre(ZSI), WB,India )(2001)More than 9years of totalteachingexperience whichinclude teachingassignments at1) Burdwan Rajcollege (1999-2000)2) Institute ofAppliedMedicines andResearch (2004-2005)3) College ofEngineering andTechnology,IILM Academyof HigherLearning(2005-2007)4) Departmentof MarineBiotechnologyDepartment ofMarineBiotechnologyand Resources;National SunYat-senUniversity,Taiwan. (2006-2007)My currentresearch interest isproteinbiotechnology. It isrelated to unfoldingand modeling theunknown part of adisease and itsmechanisms, drugdiscovery anddevelopment(specially form asignaling pathway).In particular, myresearch goalsaddress thefollowing questions Scientific AwardSnahalata BanerjeeGold Medal 1998(Academy ofEnvironmentalBiology, India) foradjudicated bestpublished researchaward(SCI, impact factor: 1.531, ranking: 13/42)First author:30 (2009 年以後 22 篇 )— 已算入corresponding author 篇數[2012]1. Chakraborty C, Roy SS, Hsu MJ, Agoramoorthy G(2012) Can computational biology improve thephylogenetic analysis of insulin? Computer Methodsand Programs in Biomedicine. doi:10.1016/j.cmpb.2011.12.001( SCI- Impact Factor 1.3) (Accepted)2. Chen WF, Chakraborty C, Sung CS, Feng CW, JeanYH, Lin YY, Huang HC, Huang TY, Huang SY, SuTM, Sung PJ, Sheu JH, Wen ZH. (2012)Neuroprotection by marine-derived compound,11-dehydrosinulariolide in an in vitro Parkinson’smodel: A promising candidate for the treatment ofParkinson’s disease. Naunyn-Schmiedeberg Archivesof Pharmacology. 385(3):265-75. [PMID: 22119889](SCI- Impact Factor 2.5)3. Tomar J, Gera VK, Chakraborty C*(2012)Detection of damaging nsSNPs on humancaspase-cascades related to apoptotic signallingpathway. Protein and Peptide Letters. (Accepted)(SCI- Impact Factor 1.8). (*Corresponding Author).4. Chakraborty C, Agoramoorthy G (2012) Stemcells in the light of evolution. Indian J. MedicalResearch (Accepted) (SCI- Impact Factor 1.8)5. Chakraborty C*, Tomar J, Gera VK (2012)AssociateProfessor,MedicalBiotechnology Division,School ofBio-SciencesandTechnology,VITUniversity,IndiaIndia

5) VidyasagarInstitute ofEducationTechnology andResearch (IILMAcademy ),(2007-2010).6) School ofBio-Sciences andTechnology, VITUniversity,Vellore,India(2010-tilldate)Conserved domains, residues, WebLogo and activesites of caspase-cascades related to apoptotic signalingpathway. Current Bioinformatics (Accepted) (SCI-Impact Factor 1.0) (*Corresponding Author).(Invited review article, Invitation to C.Chakraborty, by guest editor, Prof. Dr. Petar M.Mitrasinovic)6. Tomar J, Gera VK, Chakraborty C* (2012) Canbioinformatic methods inform us about the molecularevolution of different human caspases? CurrentBioinformatics (Accepted) (SCI- Impact Factor 1.0)(*Corresponding Author)(Invited review article, Invitation to C.Chakraborty, by guest editor, Prof. Dr. Petar M.Mitrasinovic)7. Lee HY, Magotra M, Wong TY, Chakraborty C,Liu JK (2012) ATP-dependent fructose uptake systemin Deinococcus radiodurans. Applied Microbiologyand Biotechnology. 93(3):1241-8. [PMID:21822900] (SCI- Impact Factor 3.3)[2011]8. Lin YC, Huang SY, Jean YH, Chen WF, Sung CS, KaoES, Wang HM, Chakraborty C, Duh CY, Wen ZH(2011) Intrathecal lemnalol, a natural marinecompound obtained from Formosan soft coral,attenuates nociceptive responses and the activity ofspinal glial cells in neuropathic rats. BehaviouralPharmacology. 22:739–750 [PMID: 22067479]

(SCI- Impact Factor 2.5)9. Kumar SV, Ravunny RK, Chakraborty C* (2011)Conserve domains, conserve residues and surfacecavities of C-reactive protein (CRP). AppliedBiochemistry and Biotechnology 165:497–505.(SCI-Impact Factor 1.9) [PMID: 21541851](*Corresponding Author) (All authors contributedequally).10. Chakraborty C, Agoramoorthy G, Hsu MJ (2011)Exploring the evolutionary relationship of insulinreceptor substrate family using computational biology.PLoS ONE 6(2):e16580(doi:10.1371/journal.pone.0016580) [PMID:21364910] (SCI-Impact Factor 4.4)11. Wu GJ, Chen WF, Hung HC, Jean YH, Sung CS,Chakraborty C, Lee HP, Chen NF, Wen ZH (2011)Effects of propofol on proliferation and anti-apoptosisof neuroblastoma SH-SY5Y cell line: New insightsinto neuroprotection. Brain Research 1384: 42–50.[PMID: 21315692 ] (SCI-Impact Factor 2.6)(Citation index-1)[The paper was highlighted by NewsRX, onescience news publishers in USA, on 25 thMay 2011].12. Chakraborty C, Roy SS, Hsu MJ, Agoramoorthy G(2011) Landscape mapping of functional proteins ininsulin signal transduction and insulin resistance: Anetwork based protein-protein interactionanalysis.PLoS ONE. 6(1): e16388. [PMID:21305025 ]

(doi:10.1371/journal.pone.0016388) (SCI-ImpactFactor 4.4)[The paper was highlighted by NewsRX, onescience news publishers in USA, on 22 nd March,2011 in the Life Science Weekly section].13. Roy SS # , Hsu CH, Wen ZH, Lin CS, ChakrabortyC* # (2011) A hypothetical relationship between thenuclear reprogramming factors for induced pluripotentstem (iPS) cells generation- bioinformatics andalgorithmic approach. Medical hypotheses.76(4):507–511. [PMID: 21195557] (SCI-ImpactFactor 1.4) (*Corresponding Author)( # contributedequally) (Citation index-1)[The paper was highlighted by NewsRX, onescience news publishers in USA, on 2 nd May 2011in the Biotech Business Week section].14. Purushotham D # , Ganguly C, Chakraborty C* # (2011)Targeting catechol-o-methyl transferase (COMT)inhibitors for schizophrenia: an approach to targetvalidation and rational drug design. Letters in DrugDesign & Discovery 8(2): 246-252. (SCI-ImpactFactor 0.7) (*Corresponding Author) ( # contributedequally) (Invited article, Invitation to C. Chakrabortyby Editor –In-Chief)15. Chakraborty C, Hsu CH, Wen ZH, Lin CS,Agoramoorthy G (2011) Effect of caffeine, norfloxacinand nimesulide on heartbeat and VEGF expression ofzebrafish larvae. Journal of Environmental Biology32(2): 179-183. [PMID: 21882652] (SCI-Impact

Factor 1.4)[The paper was highlighted by NewsRX, onescience news publishers in USA, on 23 rd May2011].[2010]16. Roy SS, Hsu CH, Wen ZH, Lin CS, Chakraborty C*(2010) Understanding hematopoietic stem cell mobilitypattern through mathematics. Rivista Di Biologia /Biology Forum 103(2) 172-180. [PMID: 21449201](SCI-Impact Factor 0.9) (*Corresponding Author)17. Chakraborty C*, Roy SS, Hsu CH, Wen ZH, LinCS* (2010) Network building of proteins in abiochemical pathway: a computational biology relatedmodel for target discovery and drug-design. CurrentBioinformatics 5(4):290-295 (SCI- Impact Factor1.0) (*Corresponding Author)18. Chakraborty C*, Shah KD, Cao WG, Hsu CH, WenZH, Lin CS* (2010) Potentialities of inducedpluripotent stem (ips) cells for treatment of diseases.Current Molecular Medicine 10(8):756-62(SCI-Impact Factor 5.2) [PMID: 20937020](*Corresponding Author) (Citation index-2)[The paper was highlighted by NewsRX, onescience news publishers in USA, on 11 thFebruary, 2011 in the Drug Week section].19. Chakraborty C*, Agoramoorthy G*(2010) Whyzebrafish? Rivista Di Biologia / Biology Forum103(1) 25-28. [PMID: 21110461] (SCI-Impact Factor

0.9) (*Corresponding Author)20. Agoramoorthy G, Chakraborty C, Hsu MJ. (2010)Big nation, nano dream-the prospects of India'snanotech revolution. Drug Discovery Today.15(13/14): 495-498 (SCI-Impact Factor 6.5) [PMID:20363360]21. Chakraborty C, Agoramoorthy G (2010) A specialreport on India's biotech scenario: Advancement inbiopharmaceutical and health care sectors.Biotechnology Advances. 28: 1–6 (SCI-ImpactFactor 7.6) [PMID: 19931371] (Citation index-2)[2009]22. Chakraborty C*, Hsu CH, Wen ZH, Lin CS*(2009)Anticancer drugs discovery and development frommarine organisms. Current Topics in MedicinalChemistry. 9(16):1536-45 (SCI-Impact Factor 4.1)[PMID: 19903164] (*Corresponding Author) (Citationindex-3)23. Chakraborty C*, Hsu CH, Wen ZH, Duh CY, LinCS. (2009) Drug discovery from marine resources.Current Science.97(3) 292-293. (SCI-Impact Factor0.9) (*Corresponding Author) (Citation index-1)24. Chakraborty C*, Hsu CH, Wen ZH, Lin CS* (2009)Recent advances of fluorescent technologies for drugdiscovery and development. Current PharmaceuticalDesign. 15(30): 3552-3570. (SCI- Impact Factor 4.8)(Citation index-6) (*Corresponding Author)25. Chakraborty C, Shieh P, Agoramoorthy G (2009)

India's stem cell research and developmentperspectives. Int J Hematol.89(3):406-8. (SCI-ImpactFactor 1.3) [PMID: 19288172] (Citation index-2)26. Chakraborty C*, Hsu CH, Wen ZH, Lin CS,Agoramoorthy G (2009) Zebrafish: A complete animalmodel for in vitro drug discovery and development.Current Drug Metabolism. 10(2):116-24 (SCI-ImpactFactor 3.9) (Citation index-23) [PMID: 19275547](*Corresponding Author)27. Chakraborty C, B. Sarkar, C.H. Hsu, Z.H. Wen, C.S.Lin, P. C. Shieh (2009) Future prospects ofnanoparticles on brain targeted drug delivery. Journalof Neuro-oncology. 93(2):285-6 (SCI-ImpactFactor 2.9) (Citation index-7) [PMID: 19048187][2008-2003]28. Agoramoorthy G, Chakraborty C (2007) Re:introduction to nanotechnology: potentialapplications in physical medicine and rehabilitation.American Journal of Physical Medicine &Rehabilitation, 86(12):1031-2. (SCI-Impact Factor1.8) (Citation index- 3) [PubMed ID: 18090446]29. Chakraborty C. (2007) Potentiality of smallinterfering RNAs (siRNA) as recent therapeutic targetsfor gene-silencing. Current Drug Targets, 8: 479-482.(SCI-Impact Factor 3.1) (Citation index- 31)[PubMed ID: 17504209]30. Hsu CH, Wen ZH, Lin CS, Chakraborty C * (2007)Zebrafish model: use in studying cellular mechanisms

for a spectrum of clinical disease entities. CurrentNeurovascular Research, 4:111-120. (SCI-ImpactFactor 3.1) (Citation index- 18) [PubMed ID:17348839] (*Corresponding Author) (Invited article,Invitation to C. Chakraborty by Editor –In-Chief)31. Chakraborty C (2006) Biochemical and molecularbasis of insulin resistance. Current Protein and PeptideScience,7(2): 113-121. (SCI-Impact Factor 3.9)(Citation index- 29) [PubMed ID: 16611137]32. Chakraborty C*, Nandi SS, Sarkar B, Sinha S. (2005)Over-expression and purification of recombinant eelcalcitonin and its phylogenetic analysis. Protein andPeptide Letters, 12(3) 263-269. (SCI-Impact Factor1.8) (Citation index-2) [PubMed ID: 15777276](*Corresponding Author)33. Chakraborty C*, Jana S, Nandi SS. (2005) Priondisease: A deadly disease for protein misfolding.Current Pharmaceutical Biotechnology, 6(2) 263-269.(*Corresponding Author) (SCI-Impact Factor 3.5)(Citation index-35) [PubMedID:15853695]34. Chakraborty, C. (2004) Overexpression forcommercial production of recombinant human insulinas A- chain and B-chain fusion protein in Escherichiacoli through genetic engineered plasmid. Indian Journalof pathology and Microbiology,47(4) 569-573.(Citation index-1) [PubMed ID:16295400] (SCI-Impact Factor 0.6)35. Chakraborty C*, Nandi S, Sinha S (2004)

Overexpression, purification and characterization ofrecombinant salmon calcitonin, a therapeutic protein,in Streptomyces avermitilis. Protein and PeptideLetters, 11(2) 165-173. (SCI-Impact Factor 1.8)(Citation index-8) [PubMed ID: 15078205](*Corresponding Author)36. Jana S, Chakraborty C*, Nandi S, Deb JK(2004)RNA interface: potential therapeutic targets. AppliedMicrobiology and Biotechnology, 65(6) 649-657.(SCI-Impact Factor 3.3) (Citation index-35)[PubMed ID: 15372214] (*Corresponding Author)(Invited article, Invitation to C. Chakraborty by Editor-In-Chief)37. Jana S, Chakraborty C*, Nandi S (2004) Mechanismand role of the RNA- based gene silencing .ElectronicJournal of Biotechnology, 7(3)189-200. (SCI-ImpactFactor 0.9) (Citation index-6) [BiolinecodeEJ4037] (*Corresponding Author)38. Chakraborty C*, Mungantiawar A (2003) Humaninsulin genome sequence map, biochemical structure ofinsulin for recombinant DNA insulin. Mimi Review inMedical Chemistry, 3(4) 181-291. (SCI-ImpactFactor 2.6) (Citation index-2) [PubMed ID:12769691] (*Corresponding Author)11 何一正Yi-ChengHo( 副教授 )Age:1971國立中興大學植物學研究所博士(2000.06)可開課名稱 :生物技術、生物資訊分析、生物影像處理、高等生物統計學、統計分類學、實驗設計與分析、演化1. 幾丁聚醣2. 分子動態模擬3. 微生物資源利用4. 奈米生物技術First author:4 (2009 年以後 4 篇 )— 已算入corresponding author 篇數1. Zi-Xian Liao#, Shu-Fen Peng#, Yi-Cheng Ho,Fwu-Long Mi, Barnali Maiti, Hsing-WenSung.Mechanistic study of transfection of萬能科技大學生物技術系副教授2010/7~ 迄今Taiwan

生物學、應用微生物學、微生物生態學、真菌生態學、真菌生理學、微生物生理學、藥用真菌學、微生物發酵學、蛋白質分離與純化、分析化學、天然物純化與分離、抗生素生物學、菇類學、分子分類學、奈米生物技術chitosan/DNA complexes coated by anionicpoly(γ-glutamic acid). Biomaterials. 2012, 3(11):3306–3315 (SCI, IF=7.81 Ranking 2/69).2. Fang-Yi Su, Kun-Ju Lin, Kiran Sonaje, Shiaw-PyngWey, Tzu-Chen Yenc, Yi-Cheng Ho, NilenduPanda, Er-Yuan Chuang, Barnali Maiti,Hsing-Wen Sung, Protease inhibition andabsorption enhancement by functionalnanoparticles for effective oral insulin delivery.Biomaterials. 2012, 33(9): 2801–2811 (SCI,IF=7.81 Ranking 2/69).3. Shu-Huei Yu, Shao-Jung Wu, Deh-Wei Tang,Yi-Cheng Ho, Fwu-Long Mi, Tzu-Hung Kuo,Hsing-Wen Sung, Stimuli-responsive materialsprepared from carboxymethyl chitosan andpoly(γ-glutamic acid) for protein delivery.Carbohydrate Polymers. 2012, 531–536 (SCI,IF=3.46 Ranking 3/70).4. Ho YC#, ZX Liao#, N Panda, DW Tang, SH Yu, FLMi*, HW Sung*. Self-organized nanoparticlesprepared by guanidine- and disulfide-modifiedchitosan as a gene delivery carrier. Journal ofMaterials Chemistry. 2011, 21: 16918-16927 (SCI,IF= 5.1 Ranking 19/121) (#equal contribution tofirst author).5. Yeh, T.-H., Hsu, L.-W., Tseng, M.T., Lee, P.-L.,Sonjae, K., Ho YC*, Sung HW*. Mechanism andconsequence of chitosan-mediated reversibleepithelial tight junction opening. Biomaterials.

2011, 32(26):6164-6173. (SCI, IF=7.81 Ranking2/69) (coressponding author).6. Chen KJ, Chiu YL, Chen YM, Ho YC, Sung HW*.Intracellularly monitoring/imaging the release ofdoxorubicin from pH-responsive nanoparticlesusing Forster resonance energy transfer.Biomaterials. 2011;32:2586-2592. (SCI, IF=7.81Ranking 2/69).7. Nguyen HN, Wey SP, Juang JH, Sonaje K, Ho YC,Chuang EY, Hsu C. W., Yen T. C., Lin, K. J.*,Sung, H. W.* The glucose-lowering potential ofexendin-4 orally delivered via a pH-sensitivenanoparticle vehicle and effects on subsequentinsulin secretion in vivo. Biomaterials. 2011;32:2673-2682. (SCI, IF=7.81 Ranking 2/69).8. Peng SF, Tseng MT, Ho YC, Wei MC, Liao ZX,Sung HW*. Mechanisms of cellular uptake andintracellular trafficking with chitosan/DNA/poly(gamma-glutamic acid) complexes as a genedelivery vector. Biomaterials. 2011;32:239-248.(SCI, IF=7.81 Ranking 2/69).9. Tang DW, Yu SH, Ho YC, Mi FL*, Kuo PL, SungHW*. Heparinized chitosan/poly(gamma-glutamicacid) nanoparticles for multi-functional delivery offibroblast growth factor and heparin. Biomaterials.2010;31:9320-9332. ( SCI, IF=7.81 Ranking2/69).10. Liao ZX, Ho YC, Chen HL, Peng SF, Hsiao CW,Sung HW*. Enhancement of efficiencies of the

cellular uptake and gene silencing ofchitosan/siRNA complexes via the inclusion of anegatively charged poly(gamma-glutamic acid).Biomaterials. 2010;31:8780-8788. (SCI, IF=7.81Ranking 2/69).11. Chiu YL, Ho YC, Chen YM, Peng SF, Ke CJ,Chen KJ, et al. The characteristics, cellular uptakeand intracellular trafficking of nanoparticles madeof hydrophobically-modified chitosan. J ControlRelease. 2010;146: 152-159.(SCI, IF=7.16Ranking 14/236).12. Ho,Y.C., Wu, S.J., Mi, F.L.*, Chiu, Y.L., Yu,S.H., Panda, N., Sung, H.W. 2010.Thiol-ModifiedChitosan Sulfate Nanoparticles for Protection andRelease of Basic Fibroblast Growth Factor. 2010.Bioconjugate Chem. 21, 28-39(SCI, IF=5.0Ranking 57/283).13. Sitanggang AB, Wu HS*, Wang SS, Ho YC.Effect of pellet size and stimulating factor on theglucosamine production using Aspergillus sp.BCRC 31742. Bioresource Technology 2010May;101(10):3595-3601. (SCI, IF=4.37 Ranking6/71).14. Pang, J.C., Chen, M.L., Ho, Y.C., Yang, C.Y.,Tzeng, C.C., Kao, S.S., Tsen, H.Y. Effect offermentation conditions on the enterotoxigenicity,cytotoxicity and pesticidal activity of Bacillusthuringiensis strains isolated in Taiwan. 2010.Bioresource Technology. 101. 1871-1876 (SCI,

IF=4.37 Ranking 6/71).15. Ho, Y. C., Mi, F. L.*, Sung, H. W., Kuo, P. L.Heparin-Functionalized Chitosan-AlginateScaffolds for Controlled Release of Growth Factor.International Journal of Pharmaceutics. 376 2009,69-75. (SCI, IF=3.60, PHARMACOLOGY &PHARMACY Ranking 57/249).16. Mi, F. L., Wu, Y. Y., Lin, Y. H., Sonaje, K., Ho,Y. C., Chen C. T., Juang, J. H., Sung H. W.*, OralDelivery of Peptide Drugs Using NanoparticlesSelf-Assembled by Poly(γ-glutamic acid) and aChitosan Derivative Functionalized byTrimethylation. Bioconjugate Chem. 2008, 19,1248–1255.(SCI, IF=5.0 Ranking 57/283).17. Yang, C.Y.*, Ho, Y. C., Pang, J. C., Huang, S. S.,Tschen, J. S. M.. Cloning and expression of anantifungal chitinase gene of a novel Bacillussubtilis isolate from Taiwan potato field.Bioresource Technology. 2009. 100 1454–1458(SCI, IF=4.37 Ranking 6/71).18. Jiang, Y. Z., Yang, C. Y., Houng, C. L., , Lee, C.,Ho, Y. C., Tsen., H. Y.* Identification of Bacillusspp., Escherichia coli, Salmonella spp.,Staphylococcus spp. and Vibrio spp. With 16SRibosomal DNA based oligonucleotide arrayhybridization. International Journal of FoodMicrobiology 2006. 107 131-137. (SCI, IF=3.14Ranking 7/126).12 張芳志臺灣大學擬開課程 : 生態工程技術 ( 濕 First author:5 (2009 年以後 2 篇 ) 成功大學 Taiwan

Fang-ChihChang( 助理教授 )Age:1976環境工程學研究所博士(2007.06)植生復育技術廢水處理技術綠色能源科技有害廢棄物處理與管理生質能源與永續發展地處理、環境友善材料 )綠色能源科技 ( 生質能源、酵素產柴油 )環境污染物指紋鑑定或溯源相關研究有價物質回收植生復育重金屬污染1. Chang, F. C., Lo, S. L., Ko, C. H. Recovery of copper andchelating agents from sludge extracting solutions.Separation and Purification Technology. 53 (2007),49‐56.2. Huang, S. C., Chang, F. C. * , Lo, S. L., Lee, M. Y., Wang, C.F., Lin, J. D. Production of lightweight aggregates from機械工程學系博士後(2011.01 迄今 )mining residues, heavy metal sludge, and incineratorfly ash. Journal of Hazardous Materials. 144 (2007),52‐58.3. Chang, F. C., Lo, S. L., Lee, M. Y., Ko, C. H., Lin, J. D.,Huang, S. C., Wang, C. F. Leachability of metals fromsludge‐based artificial lightweight aggregate. Journalof Hazardous Materials. 146 (2007), 98‐105.4. Huang, S. C., Chang, C. Y., Mui, D. T., Chang, F. C., Lee,M. Y., Wang, C. F. Sequential extraction for evaluatingthe leaching behavior of selected elements inmunicipal solid waste incineration fly ash. Journal ofHazardous Materials. 149 (2007), 180‐188.5. Chang, F. C., Lo, S. L., Ko, C. H. A copper removalprocess for printed circuit board wastewater sludgeapplying extraction and cementation with chelatingagents recovery. Environmental Engineering Science.24(8) (2007), 1006‐1016.6. Lee, M. Y., Ko, C. H., Chang, F. C. * , Lo, S. L., Lin, J. D.Artificial stone slab production using waste glass, stonefragments and vacuum vibratory compaction. Cementand Concrete Composites. 30(7) (2008), 583‐587.7. Fan, C. H., Chang, F. C., Ko, C. H., Teng, C. J., Chang, T.

C., Sheu, Y. S. Treatment of septic tank effluents by afull scale capillary seepage soil biofiltration system.Journal of Environmental Health. 71 (7) (2009), 56‐60.8. Fan, C. H., Chang, F. C., Ko, C. H., Teng, C. J., Chang, T.C., Sheu, Y. S. Pollutant removals of an urban riparianartificial wetland and its reconstruction in Taipei basinafter typhoon Aere. Ecological Engineering. 35 (3)(2009), 424‐435.9. Ko, C. H., Chen, P. J., Chen, S. H., Chang, F. C. * , Lin, F. C.,Chen, K. K. Extraction of chromium, copper, andarsenic from CCA‐treated wood using biodegradablechelating agents. Bioresource Technology. 101 (5)(2010), 1528‐1531.10. Chen S.H., Wang Y.W., Hsu J.L., Chang H.Y., Wang C.Y.,Shen P.T., Chiang C.W., Chuang J.J., Tsai H.W., Gu P.W.,Chang F. C., Liu H.S., Chow N.H. Nucleophosmin in thePathogenesis of Arsenic‐related BladderCarcinogenesis Revealed by Quantitative Proteomics.Toxicology and Applied Pharmacology. 242 (2) (2010),126‐135.11. Chang, F. C. * , Lee, M. Y., Lo, S. L., Lin, J. D., Ko, C. H..Artificial aggregate made from recycled sludge andwaste silt using vibratory compaction. Journal ofEnvironmental Management. 91 (2010), 2289‐2294.12. Ko, C.H., Chang, F. C.*, Lee, T.M.*, Chen, H.H., Hsieh,H.L., Guan, C.Y. Impacts of Typhoon Inundation onPollutant Removal Performances of a SubtropicalUrban Constructed Wetland. Science of the TotalEnvironment. 408 (2010), 4328‐4333.

13. Chang, F. C.*, Lin, J. D., Tsai, C. C., Wang, K. S. Study onconcrete made with thermal power plant sludge ash.Water Science and Technology. 62 (2010), 1689‐1693.14. Wang, Y. C., Ko, C. H. * , Chang, F. C. * , Chiou, C. R.,Chuang C. S., Liu, T. F., Hsieh, H. L., Teng, C. J. CarbonSequestration and Bio‐energy Production Potential forAboveground Biomass from a Subtropical ConstructedWetland. Biomass and Bioenergy. (2010), In Press.15. Ko, C.H., Lee, T.M., Chang, F.C., Liao, S.P. TheCorrelations between System TreatmentEfficiencies and Aboveground EmergentMacrophyte Nutrient Removal for the Hsin‐HaiBridge Phase II Constructed Wetland. BioresourceTechnology. (2010), In Press.16. Chen, W.S., Chang, F. C. * , Shen, Y.H., Tsai, M.S. Thecharacteristics of organic sludge/sawdust derived13 洪紹文(Shao-WenHung)( 助理教授 )AGE:1974Department ofVeterinaryMedicine,College ofVeterinaryMedicine,NationalChungHsingUniversity,中興大學(1999.06)Teaching Courses inUniversity• Ornamental FishDiseases ( 觀賞魚疾病學 ;2 學分 )• Fish Histopathology( 魚類組織病理學 ;3學分 )• Fish ClinicalPathology ( 魚類臨床病理學 ;2 學分 )• Fish Anesthesia ( 魚Research interests:1. Fish Diseases &Therapy2. Fish Culture3. Biology4. Oncology5. Immunology6. Flow Cytometry7. Cancer Metastasis8. Cancer Medicine9. ExperimentalAnimalfuel. Bioresource Technology. (2010), In Press.First author:6 (2009 年以後 0 篇 )1.*Chu RM, Lin CY, Liu CC, Yang SY, Hsiao YW,Hung SW, Pao HN, Liao KW. 2001. Proliferationcharacteristics of canine transmissible venerealtumor. Anticancer Research 21: 4017-4024.【SCI;IF: 1.656】2. Hsiao YW, Liao KW, Hung SW, *Chu RM. 2002.Effect of tumor infiltrating lymphocytes on theexpression of MHC molecules in caninetransmissible venereal tumor cells. VeterinaryPostdoctoral fellowshipinAgriculturalBiotechnologyResearchCenter,AcademiaSinica(2012.1-Present)Taiwan

類麻醉學 ;2 學分 )• Fish Surgery ( 魚類外科 ;2 學分 )• Fish & ShellfishCulture ( 魚類與甲殼類養殖學 ;2 學分 )• Fish & ShellfishImmunology ( 魚類與甲殼類免疫學 ;2 學分 )• Animal Welfare ( 動物福利學 ;2 學分 )• ExperimentalAnimals andPractices ( 實驗動物學與實習 ;2 學分 )• Biology ( 基礎生物學 ;2 學分 )Teaching Courses inGraduate School• Species, Cultureand Breeding ofOrnamental Fish ( 觀賞魚的品種、飼養與繁殖 ;2 學分 )• Species, Cultureand Breeding ofPleco and Corydoras10. Animal Welfare Immunology and Immunopathology 87: 19-27.【SCI; IF: 2.176】3.1Liao KW, 1Hung SW, Hsiao YW, Bennett M,*Chu RM. 2003. Canine transmissible venerealtumor cell depletion of B lymphocytes: molecule(s)specifically toxic for B cells. VeterinaryImmunology and Immunopathology 92: 149-162.【SCI; IF: 2.176】(1Contributed equally to thiswork)4. Hsiao YW, Liao KW, Hung SW, *Chu RM. 2004.Tumor-infiltrating lymphocyte secretion of IL-6antagonizes tumor-derived TGF-beta 1 and restoresthe lymphokine-activated killing activity. Journal ofImmunology 172: 1508-1514.【SCI; IF: 5.745】5. *Wang WS, Hung SW, Lin YH, Shih CW, Tu CY,Tung KC, Chen PR, Ooi HK. 2006. Parasitosis ofshort-finned eel, Anguilla australis schmidti, inTaiwan. Bulletin of the European Association ofFish Pathologists 26: 106-111. 【SCI; IF: 0.414】6. Tu CY, Ho SP, Hung SW, Chen BR, Tsou LT,*Wang WS. 2006. Development of a technique todetect the residue of oxolinic acid in the serum andmuscle of Chinese mitten crab, Eriocheir Sinensis.Journal of Food and Drug Analysis 14: 391-397.

( 異型與鼠魚的品種、飼養與繁殖 ;2學分 )• Introduction ofConnection andFunctions ofPeripheral EquipmentFor Ornamental FishCulture( 簡介觀賞魚飼養缸周邊設備配置與功用 ;2 學分 )• Clinical Drugs andTreatment For FishDiseases ( 臨床魚病用藥與治療 ;2 學分 )• Discussion ofClinical Fish Cases( 臨床病例討論 ;1 學分 )• Principle andProduction ofPolyclonal andMonoclonalAntibodies ( 多株與單株抗體原理與製造 ;2 學分 )• Biotechniques andPractices ( 生物技術與實習 ;2 學分 )【SCI; IF: 0.615】7. Hung SW, Tu CY, Tsou LT, Chang CH, Lin CC,*Wang WS. 2006. A case of swollen abdomendisease in giant grouper, Epinephelus lanceolatus,remedied by vitamin C and E supplementation.Bulletin of the European Association of FishPathologists 26: 267-270.【SCI; IF: 0.414】8. Hung SW, Tu CY, *Wang WS. 2007. In vivoeffects of adding singular or combined anti-oxidativevitamins and/or minerals to diets on the immunesystem of tilapia (Oreochromis hybrids) peripheralblood monocyte-derived, anterior kidney-derived,and spleen-derived macrophages. VeterinaryImmunology and Immunopathology 115: 87-99.【SCI; IF: 2.176】9. *Wang WS, Hung SW, Lin YH, Tu CY, WongML, Chiou SH, Shieh MT. 2007. The effects of fivedifferent glycans on innate immune responses byphagocytes of hybrid tilapia and Japanese eelsAnguilla japonica. Journal of Aquatic Animal Health19: 49-59.【SCI; IF: 0.924】10. Hung SW, Shih CW, Chen BR, Ling YF, TsouLT, Tu CY, Ho SP, *Wang WS. 2007. A newdetection technique for fluoroquinolone-conjugatedproteins by high performance liquid chromatography

with UV/fluorescence detectors. Journal of Food andDrug Analysis 15: 71-74.【SCI; IF: 0.615】11. Hung SW, Tu CY, *Wang WS. 2007. In vitroeffects of singular or combined anti-oxidativevitamins and/or minerals on tilapia (Oreochromishybrids) peripheral blood monocyte-derived, anteriorkidney-derived, and spleen-derived macrophages.Fish & Shellfish Immunology 23: 1-15【. SCI; IF:3.044】12. Tu CY, Hung SW, Tsou LT, Chang YC, *WangWS. 2007. Simultaneous flow cytometric assessmentfor cellular types and phagocytic abilities of thehaemocytes of the hard clam, Meretrix Lusoria. Fish& Shellfish Immunology 23: 16-23.【SCI; IF:3.044】13. *Wang WS, Hung SW, Lin YH, Tu CY, WongML, Chiou SH, Shieh MT. 2007. Purification andlocalization of nitric oxide synthases from hybridtilapia (Nile Tilapia × Mozambique Tilapia). Journalof Aquatic Animal Health 19: 168-178.【SCI; IF:0.924】14. Hung SW, Wang SL, Tu CY, Tsai YC, Chuang

ST, Shieh MT, Liu PC, *Wang WS. 2008. Antibioticsusceptibility and prevalence of erythromycinribosomal methylase gene, erm(B) in Streptococcusspp. Veterinary Journal 176: 197-204. 【SCI; IF:2.796】15. Lin CC, Hung SW, Tu CY, Tsou LT, Shieh MT,Lin SL, Liu PC, *Wang WS. 2008. Spontaneousstomach lymphoma and liver metastases in flowerhorn fish (hybrid cichlid). Bulletin of the EuropeanAssociation of Fish Pathologists 28: 115-120.【SCI;IF: 0.414】16. Huang YC, Hung SW, Jan TJ, Liao KW, WangYS, Cheng CH, *Chu RM. 2008. CD5-lowexpression lymphocytes in canine peripheral bloodshow characteristics of natural killer cells. Journal ofLeukocyte Biology 84: 1501-1510.【SCI; IF: 4.626】17. Liu PC, Lin CC, Lin SL, Chen MH, Lee OH, ChenYK, Tung KC, Chen YP, Tu CY, Hung SW, *WangWS. 2011. Vesicular diseases associated withpoxvirus-like infection in cultured soft shell turtles(Pelodiscus sinensis) in Taiwan. Bulletin of theEuropean Association of Fish Pathologists 31:73-80.

【SCI; IF: 0.414】備註 : 本文之病理切片照片被選為封面18. Chen TA, Wang JL, Hung SW, Chu CL, ChengYC, *Liang SM. 2011. Recombinant VP1, an Aktinhibitor, suppresses progression of hepatocellularcarcinoma by inducing apoptosis and modulation ofCCL2 production. PLoS ONE 6: e23317.【SCI; IF:4.411】19. Liu PC, Hung SW, Chen MH, Cheng CF, Lin CC,Chang CH, Lin SL, Tu CY, Lin YH, *Wang WS.2011. Highly virulent Photobacterium damselaesubsp. piscicida isolated from Taiwan paradise fish,Macropodus opercularis (L.), in Taiwan. AfricanJournal of Microbiology Research 5: 2107-2113.【SCI; IF: 0.528】20. Peng JM, Chen YH, Hung SW, Chou CF, HoMY, Lee YJ, Lai TC, Hsiao M, *Liang CM, *LiangSM. 2012. Recombinant viral protein promotesapoptosis and suppresses invasion of ovarianadenocarcinoma cells by targeting α5β1 integrin todownregulate Akt and MMP-2. British Journal ofPharmacology 165: 479-493.【SCI; IF: 4.925】21. Liu PC, Wang CY, Lin SL, Lin CC, Hung SW,

Chang CH, Tu CY, Chen MH, Yi-Peng Chen YP,*Wang WS. 2011. Establishment of a soft shellturtle, Pelodiscus sinensis, embryo primary cellculture for studies of soft shell turtle poxvirus-likevirus replication and characteristics. African Journalof Microbiology Research 6: 960-967.【SCI; IF:0.528】22. Chen MH, Hung SW, Shyu CL, Lin CC, Liu PC,Chang CH, Shia WY, Cheng CF, Lin SL, Tu CY,Lin YH, *Wang WS. 2011. Lactococcus lactissubsp. lactis infection in Bester sturgeon, a culturedhybrid of Huso huso × Acipenser ruthenus, inTaiwan. Research in Veterinary Science.【SCI;IF:1.330】(in press)23. Cheng CF, Hung SW, Chang YC, Chen MH,Chang CH, Tsou LT, Tu CY, Lin YH, Liu PC, LinSL, *Wang WS. 2012. Purification andcharacterization of hemagglutinating proteins fromPoker-chip Venus (Meretrix lusoria) and Corbiculaclam (Corbicula fluminea).TheScientificWorldJOURNAL.【SCI; IF: 1.524】(inpress)24. Chiu CF, Ho MY, Peng JM, Hung SW, Lee WH,*Liang CM, *Liang SM. 2012. Raf activation by Ras

and promotion of cellular metastasis requirephosphorylation of prohibitin in the raft domain ofplasma membrane. Oncogene.【SCI; IF: 7.414】(inpress)25. Chiu CF, Peng JM, Hung SW, *Liang CM,*Liang SM. 2012. Recombinant viral capsid proteinVP1 suppresses migration and invasion of humancervical cancer by modulating phosphorylatedprohibitin in lipid rafts. Cancer Letters. 【SCI; IF:4.864】(in proof)14 董哲煌Che-huangTung( 助理教授 )AGE:1971AucklandUniversityofTechnology博士(2010)預計可開授的課程列表 ( 預估學分數 )1. 魚類增養殖學及實習 (2+1)2. 無脊椎動物增養專長領域 :1. 水產動物營養生理 ,2. 飼料營養學 ,3. 繁殖生理 ,First author:6 (2009 年以後 5 篇 )1. C. W. Tung, C. S. wang and S. N. Chen (1999)Histological and electron microscopic study onMacrobrachium muscle virus (MMV) infection in中研院細生所博士後研究員(2011~ 目前 )Taiwan殖學及實習 (2+1)4. 種苗繁殖 ,the giant freshwater prawn Marcobrachium3. 水產儀器分析概5. 餌料生物培養 ,rosenbergii (de Man), culture in Taiwan. Journal of論及實習 (2+1)6. 藻類學 ,Fish Diseases, 22: 319‐322.(SCI)4. 養殖循環水系統7. 循環水系統設2. Yao Chang, Che‐Huang Tung, Yu‐Tzu Huang, Jean理論與設計 (2+1)計管理 ,Lu, Jen‐Yang Chen, and Ching‐Hwa Tsai (1999)5. 水產餌料生物培8. 無脊椎動物學 ,Requirement for cell‐to‐cell contact in養及實習 (2+1)9. 動物組織學 ,Epstein‐Barr virus infection of nasopharyngeal10. 動物技術 ( 各種carcinoma cells and keratinocytes. Journal of其他可以開設的課切片制備及觀Virology 73(10): 8857‐8866.(SCI)程 :察 ),3. Che-Huang Tung and Andrea C. Alfaro (2011)1. 普通生物學11. 電子顯微鏡學 ,Initial attachment, metamorphosis, settlement, and

2. 動物技術及電子顯微鏡學3. 無脊椎動物學12. 儀器分析 survival of black-footed abalone, Haliotis iris, onmicroalgal biofilms containing different aminoacid compositions. Journal of World AquacultureSociety 42(2): 167-183, DOI:10.1111/j.1749-7345.2011.00454.x. (SCI)4. Che-Huang Tung and Andrea C. Alfaro (2011)Effects of dual microalgal species biofilms onNew Zealand black-footed abalone (Hailotis iris)larval/post-larval processes. Journal of AppliedAquaculture 23(1): 14-31, DOI:10.1080/10454438.2011.549779. (SCI)5. Che-Huang Tung and Andrea C. Alfaro (2011)Effect of dietary protein and temperature on thegrowth and health of juvenile New Zealandblack-footed abalone (Haliotis iris). AquacultureResearch 42(3): 366-385, DOI:10.1111/j.1365-2109.2010.02631.x. (SCI)6. Che-Huang Tung and Andrea C. Alfaro (2011)Effect of dietary and amount on shell morphologyof juvenile abalone Haliotis iris. Journal ofFishery and Aquatic science 6(2): 107-118, DOI:10.3923/jfas 2011.107.118.7. Che-Huang Tung and Andrea C. Alfaro (2012)Alternative protein sources in artificial feeds forNew New Zealand black-footed abalone (Haliotisiris, Martyn 1784) juveniles. Journal ofWorldAquaculture Society 43(1): 1-29, DOI:10.1111/j.1749-7345.2011.00545.x. (SCI)書本

1. Che-Huang Tung "Dietary Protein Requirementsof the New Zealand Black-footed Abalone" (ISBN978-3-8454-0208-6) LAP (LAMBERT AcademicPublishing) GmbH & Co. (KGDudweilerLandstra.e 99, 66123 Saarbr.cken, Germany)15 李學德Hsueh-TeLee( 助理教授 )AGE:1971成功大學基礎醫學研究所博士(2006.06)可開授課程 :1. Cell Biology2. Neural plasticityin developingbrain3. BehavioralNeuroscience andMethodology4. Physiology(includeexperiments)5. Tumor MetastasisBiology專長領域 :1. 神經醫學、2. 癌症醫學、3. 血管醫學First author:5 (2009 年以後 3 篇 )已發表主論文 ( 代表著作 ):1. Hsueh‐Te Lee, Ying‐Chao Chang, Yi‐Fang Tu andChao‐Ching Huang. VEGF‐A /VEGFR‐2 signalingleading to CREB phosphorylation is a sharedpathway underlying the protective effect ofpreconditioning on neurons and endothelial cells.J. Neurosci. 2009, 29(14): 4356‐436. (SCI,國立成功大學醫學院小兒科 -博士後研究員TaiwanTo cooperate withIF=8.205)other courses:1. Neuroscience.2. Oncology3. Animal modeldesign andtechnology.2. Hsueh‐Te Lee, Ying‐Chao Chang, Yi‐Fang Tu, Chao‐ChingHuang. CREB Activation Mediates VEGF‐A’sProtection of Neurons and Cerebral VascularEndothelial Cells. J Neurochem 2010;113:79‐91.(SCI, IF=4.852)已發表參考論文 ( 參考著作 ):1. Wen‐Tai Chiu*, Hsueh‐Te Lee*, Feng‐Ju Huang, KennethD. Aldape, Jun Yao, Patricia S. Steeg, Cheng‐Yang Chou,Zhimin Lu, Keping Xie, and Suyun Huang. Caveolin‐1Upregulation Mediates Suppression of Primary

Breast Tumor Growth and Brain Metastases byStat3 Inhibition. (* two authors contributedequally to this work) Cancer Research (2011);71(14): 4932‐4943 (SCI, IF=8.234).2. Nu Zhang, Ping Wei, Aihua Gong, Wen‐Tai Chiu,Hsueh‐Te Lee, Howard Colman, He Huang, Jianfei Xue,Mingguang Liu, Yong Wang, Raymond Sawaya, KepingXie, W.K. Alfred Yung, Rene´ H. Medema, Xi He, andSuyun Huang. FoxM1 Promotes b‐Catenin NuclearLocalization and Controls Wnt Target‐GeneExpression and Glioma Tumorigenesis. Cancer Cell(2011); 20: 427–442. (SCI, IF=26.925)3. Wan‐Ying Lin, Ying‐Chao Chang, Hsueh‐Te Lee,Chao‐Ching Huang. CREB activation in the rapid,intermediated, and delayed ischemicpreconditioning against hypoxic‐ischemia inneonatal rat. J Neurochem 2009;108:847‐859. (SCI,IF= 4.337)4. Yu‐Min Ku, Keng Chen Liang, Hsiang‐Hua Chen,Chianfang G. Cherng, Hsueh‐Te Lee, Yinchiu Lin, A‐MinHuang, Ruey‐Ming Liao, Lung Yu. Cocaine‐but notmethamphetamine‐associated memory requiresde novo protein synthesis. Neurobiology ofLearning and Memory (2007) ;87:93–100. (SCI,IF=3.701)

5. Ying‐Chao Chang, Shun‐Fen Tzeng, Lung Yu, A‐MinHuang, Hsueh‐Te Lee, Chao‐Ching Huang andChien‐Jung Hog. Early‐life fluoxetine exposurereduced functional deficits afterhypoxic–ischemia brain injury in rat pups.Neurobiology of Disease (2006) ; 24:101–113.(SCI, IF= 5.121)6. Hsueh‐Te Lee, BS, Ying‐Chao Chang, MD, PhD, Lin‐YuWang, MD, Shan‐Tair Wang, PhD, Chao‐Ching Huang,MD and Chien‐Jung Ho, BS. cAMP ResponseElement‐Binding Protein Activation in LigationPreconditioning in Neonatal Brain. Ann Neurol(2004); 56:611–623. (SCI, IF= 10.746)7. Hsueh‐Te Lee, Li‐Li Chiu, Tzong‐Shyuan Lee, Hui‐LingTsai and Lee‐Young Chau. Dietary Iron RestrictionIncreases Plaque Stability inApolipoprotein‐E‐Deficient Mice. J Biomed Sci(2003);10:510–517. (SCI, IF=2.015)16 楊雅婷YA-TING(TINA)YANG( 助理教授 )AGE:1980UniversityofCanterbury,Christchurch, NewZealand生命科學系博士(2010.04)可開授的課程 :1. 生物化學2. 自由基生物化學3. 細胞生物學4. 癌症生物學5. 內分泌學專長領域 :1. 分子生物2. 生物化學First author:1 (2009 年以後 1 篇 )1. Yang, Y‐T., Whiteman, M., and Gieseg, S.P (2012).HOCl causes necrotic cell death in humanmonocyte derived macrophages through calciumdependent calpain activation. Biochimica et台灣國立中山大學博士後研究(2010.05~2012.07)TaiwanBiophysica Acta 1823 (2): 420‐9 [Epub 2011 Oct].Impact factor 4.733.2. Yang, Y‐T., Whiteman, M., and Gieseg, S.P.

Intracellular glutathione protects humanmonocyte derived macrophages fromhypochlorite damage (re‐submitted for minorcorrections before publication from Life Sciences).Impact factor 2.451.3. Ong, C‐W., Yang, Y‐T., Liu, M‐C., Fox, K.R, Liu, P‐H.,Tung, H‐W (2012). Synthesis of directly linkeddiazine isosteres of pyrrole‐polyamide thatphotochemically cleave DNA. Org Biomol Chem.10(5): 1040‐6 [Epub 2011 Dec]. Impact factor3.761.4. Gieseg, S.P., Amit, Z., Yang, Y‐T., Shchepetkina, A.and Katouah, H (2010). Oxidant production,oxLDL uptake, and CD36 levels in humanmonocyte‐derived macrophages aredownregulated by the macrophage‐generatedantioxidant 7,8‐dihydroneopterin. Antiox RedoxSignal 13(10): 1525‐34. Impact factor 7.581.5. Gieseg,S.P., Leake, D.S., Flavall, E., Amit, Z. andYang, Y‐T (2009). Macrophage antioxidantprotection within atherosclerotic plaques.Frontiers in Bioscience 14: 1230‐46. Impact factor3.308.6. Firth, C.A., Yang, Y‐T., and Gieseg, S.P (2007).Lipid oxidation predominates over protein

hydroperoxide formation in humanmonocyte‐derived macrophages exposed toaqueous peroxyl radicals. Free Radic Res 41(7):17 廖健森Liao,Chien-Sen( 助理教授 )AGE:1987博士 : 國立台灣大學農業化學研究所(2002~2006)輔修『系統生物與生物資訊學程』可教授課程 :一、環境化學領域 :1. 環境毒物學特論2. 儀器分析化學3. 普通化學4. 海洋環境污染化學二、環境生物領域 :1. 環境微生物學2. 土壤微生物學3. 微生物生態學4. 高等微生物學5. 生物復育特論6. 生物技術特論三、其它 :1. 分子生物學2. 生物化學3. 論文寫作與選讀未來教學計畫 :配合國立中山大學海洋生物科技暨資源學系的教學規劃 , 可開授目前所上預定發展的課程 , 例研究專長 :1. 環境毒物學、2. 微生物生態、3. 植生復育、4. 蛋白質體學、5. 生質能源、6. 藻類學839‐848. Impact factor 2.826.First author:5 (2009 年以後 4 篇 )1. Liao, C. S., Yuan, S. Y., Hung, B. H., Chang, B.V., "Removal of organic toxic chemicals usingthe spent mushroom compost of Ganodermalucidum" J. Environ. Monitor., accepted.2. Hsu, W. M., Hsi, H. C., Huang, Y. D., Liao, C. S.,Hseu, Z. Y., " Partitioning of arsenic in soil-cropsystems irrigated using groundwater: a case studyof rice paddy soils in southwestern Taiwan"Chemosphere, vol.86, pp.606-613, 2012.02.3. Weng, C. H., Lin, Y. T., Yuan, C., Liao, C. S.,"Sludge dewatering assisted by an electrokineticprocess", Journal of Science and Technology, vol.4, no. 45, pp. 149-154, 2011.07.4. Liao, C. S. "Biodegradation of di-n-butylphthalate in a soil microcosm," J. Environ. Sci.Health. B, vol.45, pp.366-371, 2010.05.5. Liao, C. S., Chen, L. C., Chen, B. S., Lin, S. H.,"Bioremediation of endocrine disruptordi-n-butyl phthalate ester by Deinococcusradiodurans and Pseudomonas stutzeri,"Chemosphere, vol.78, pp.342-346, 2010.01.6. Liao, C. S., Yen, J. H., Wang, Y. S., "Growthinhibition in Chinese cabbage (Brassica rapa var.義守大學土木與生態工程學系環境生態組助理教授(2007/7~)Taiwan

如微生物生態學、環境微生物學等。亦可配合開設目前已有課程之延伸學分 , 例如海洋環境污染化學與環境毒物學特論等。chinensis) growth exposed to di-n-butylphthalate,"J. Hazard. Mater., vol.63, pp.625-631,2009.04.7. Liao, C. S., Yen, J. H., Wang, Y. S., "Effects ofendocrine disruptor di-n-butyl phthalate on thegrowth of Bok choy (Brassica rapa subsp.chinensis)," Chemosphere, vol.65,pp.1715–1722, 2006.01.8. Chang, B. V., Liao, C. S., Yuan, S. Y., "Anaerobicdegradation of diethyl phthalate, di-n-butylphthalate, and di-(2-ethylhexyl) phthalate fromriver sediment in Taiwan," Chemosphere, vol.58,pp.1601–1607, 2005.01.9. Chang, B. V., Liao, C. S., Yuan, S. Y., "Anaerobicdegradation of di-n-butyl phthalate anddi-(2-ethylhexyl) phthalate in sludge," Bull.Environ. Contam. Toxicol., vol.75, pp.775-782,2005.01.10. Wang, C. C., Chang, C. W., Chu, C. P., Lee, D. J.,Chang, B. V., Liao, C. S., "Efficient productionof hydrogen from wastewater sludge," J. Chem.Technol. Biotechnol., vol.79, pp.426-427,2004.01.11. Wang, C. C., Chang, C. W., Chu, C. P., Lee, D. J.,Chang, B. V., Liao, C. S., "Producing hydrogenfrom wastewater sludge by Clostridiumbifermentans," J. Biotechnol., vol.102, pp.83-92,2003.01.12. Wang, C. C., Chang, C. W., Chu, C. P., Lee, D. J.,

Chang, B. V., Liao, C. S., Tay, J. H., "Usingfiltrate of waste biosolids to effectively producebio-hydrogen by anaerobic fermentation," Wat.Res., vol.37, pp.2789-2793, 2003.01.13. Chu, C. P., Lee, D. J., Chang, B. V., You, C. H.,Liao, C. S., Tay, J. H., "Anaerobic digestion ofpolyelectrolyte flocculated waste activatedsludge," Chemosphere, vol.53, pp.757–764,2003.01.14. Wang, C. C., Chang, C. W., Chu, C. P., Lee, D. J.,Chang, B. V., Liao, C. S., "Hydrogen productionfrom wastewater sludge using a clostridiumstrain," J. Environ. Sci. Health A., vol.38,pp.1867-1875, 2003.01.15. Yuan, S. Y., Liu, C., Liao, C. S., Chang, B. V.,"Occurrence and microbial degradation ofphthalate esters in Taiwan river sediments,"Chemosphere, vol.49, pp.1295-1299, 2002.01.16. Chu, C. P., Chang, B. V., Liao, C. S., Jean, D. S.,Lee, D. J., "Observations on changes inultrasonically treated waste activated sludge,"Wat. Res., vol.35, pp.1038-1046, 2001.01.17. Chu, C. P., Lee, D. J., Chang, B. V., Liao, C. S.,"Effect of polyacrylamide on microbial densitylevels in waste activated sludge," J. Chem. Tech.Biotechnol., vol.76, pp.598-602, 2001.01.18. Chu, C. P., Lee, D. J., Chang, B. V., Liao, C. S.,"Using ATP bioluminescence techniques formonitoring microbial activity in sludge,"

Biotechnol. Bioengng., vol.75, pp.469-474,2001.01.19. Chu, C. P, Lee, D. J., Chang, B. V., Liao, C. S.,"Effects of acid and alkaline pretreatments onwaste activated sludge.," Asian J. of Microbiol.Biotech. & Env. Sci., vol.2, pp.5-9, 2000.01.20. Jean, D. S., Chang, B. V., Liao, C. S., Tsou, G.W., Lee D. J., "Reduction of microbial densitylevel in sewage sludge through pH adjustmentand ultrasonic treatment.," Wat. Sci. Tech.,vol.42, pp.97-102, 2000.01.18 SupiramaniyamSivakumar( 助理教授 )AGE:1974BharathiarUniversityEnvironmentalSciencesPhD(2004.03)my interaction withstudents will create asense of conditionsand an atmospherewhere my studentscan learn, and acquirean education thatpermits each studentto play a self assignedrole in society. So, ifselected for the Postof AssistantProfessor, I can frameeach student to learn,to analyse, toencourage, tocriticize, and tochallenge, so as toMy researchinterests will befocused in1. My researchinterests includetopics ofaquaculturetechniques, andtoxicology,ecophysiologyand behaviourof aquaticorganisms,particularlylarval andjuvenilecrustaceans.2. Identifyingmetal resistantmicroorganismsand marinemacro algaeFirst author:10 (2009 年以後 6 篇 ) — 已算入corresponding author 篇數1. H. Kasthuri, K. Shanthi, S. Sivakumar *, S.Rajakumar, H. K. Son, Y. C. Song (2011). Influence ofmunicipal solid waste compost (MSWC) on the growthand yield of green gram (Vigna radiate (L) Wilczek),fenugreek (Trigonella foenum-graecum L.) and on soilquality. Iranian Journal of Environmental HealthScience & Engineering. 8(3): 285-294.2. S. Sivakumar *, Y.C. Song, I.S. Park, S.H. Cho, C.Y. Lee,Boo Gil Kim (2010). Short term influence of phosphateand nitrate on heavy metal accumulation by red algaAcrosorium uncinatum. Environmental Monitoringand Assessment, 165: 449‐460.3. Young‐Chae Song, Subpiramaniyam Sivakumar *,Jung‐Hui Woo, Sung‐Jung Ko, Eung‐Ju Hwang, Qtae Jo.(2010). Removal of Cochlodinium polykrikoides bydredged sediment: A field study. Harmful Algae. 9:227‐232.4. K. Rajkumar, S. Sivakumar *, P. Senthilkumar, D.Prabha, C. V. Subbhuraam, Y. C. Song. (2009). Effectsof selected heavy metals (Pb, Cu, Ni and Cd) in theaquatic medium on the restoration potential andaccumulation in the stem cuttings of the terrestrialplant, Talinum triangulare Linn. Ecotoxicology, 18:Dept. ofHealth andEnvironment, KosinUniversity,SouthKorea(2010.08 –Till date)India

impel to furtherprospects.and byidentifying newgenes andpathways.3. Further I aminterested topursuing thebehaviour,toxicology andphysiologicalecology ofmarine larvaeand juvenilesand theirpotentialapplications inaquaculture.For example, abetterunderstandingof toxicchemicalsespeciallyheavy mealsmetals thataffect larvalforaging andprey selection,feeding952-960.5. Young Chae Song, S. Sivakumar *, Tien ThanhNguyen, Soo-Hong Kim, Boo Gil Kim. (2009). Theimmobilization of heavy metals in biosolids usingphosphate amendments - Comparison of EPA (6010and 3051) and selective sequential extraction methods.Journal of Hazardous Materials, 167: 1033-1037.6. S. Sivakumar *, H. Kasthuri, D.Prabha, P.Senthilkumar, C. V. Subbhuraam, Y. C. Song. (2009).Efficiency of composting parthenium plant and neemleaves in the presence and absence of an oligochaete,Eisenia fetida. Iranian Journal of EnvironmentalHealth Science & Engineering. 6(3): 201-208.7. Mohanapriya S, P. Senthilkumar, S. Sivakumar *, M.Dineshkumar and C.V. Subbhuraam. (2006). Effects ofcopper sulfate and copper nitrate in the aquatic mediumon the restoration potential and accumulation of copperin the stem cuttings of the terrestrial medicinal plant,Portulaca oleracea Linn. Environmental Monitoringand Assessment, 121: 233-244.8. R. Deepa, P. Senthilkumar. S. Sivakumar *, P.Duraisamy and C.V. Subbhuraam. (2006). Copperavailability and accumulation by Portulaca oleraceaLinn stem cutting. Environmental Monitoring andAssessment, 116(1-3): 185-195.9. P. Senthilkumar, SPM. Prince. W, S. Sivakumar * andC.V. Subbhuraam (2005). Prosopis juliflora – A greensolution to decontaminate heavy metal (Cu and Cd)contaminated soils. Chemosphere, 60(10): 1493-1496.10. Sivakumar. S * and C. V. Subbhuraam. (2005).Toxicity of chromium (III) and (VI) to the earthwormEisenia fetida. Ecotoxicology and EnvironmentalSafety, 62(1): 93-98.11. Rajeswarisivaraj, S. Sivakumar, P. Senthilkumar andV. Subburam. (2001). Carbon from cassava peel, anagricultural waste, as an adsorbent in the removal ofdyes and metal ions from aqueous solutions.Bioresource Technology, 80: 233 – 235.12. SPM. Prince W, S. Sivakumar, V. Ravi and V.Subburam (2000). The Effect of Coirpith compost onthe growth and quality of leaves of the mulberry plantMorus alba L. Bioresource Technology, 72 (1): 95-97.(* Corresponding author)

hythms,aggressive andcannibalisticbehaviour,metamorphosisand settlementwill havesignificantimplications fordevelopment ofsoundaquaculturetechniques.Similarly,quantifyingacute andchronic toxiceffects ofvariouspollutants, suchas nutrients ineffluent water,to culturedspecies andunderstandingtheir underlingphysiologicalmechanismswill help reduce

isks andimproveproductivity in19 陳容甄( 助理教授 )AGE:?國立成功大學環境醫學研究所毒理組博士(2010/06)可教授課程 :1. 醫技系相關科目如血清免疫學、血液學及臨床鏡檢學等。2. 生物技術 : 介紹PCR,Real-TimePCR,Q-PCR,Western Blot,Southern Blot, DNAarray,Transfection,Flow cytometry, 動物實驗、IVIS 等分生技術及應用。3. 分子生物學 : 介紹DNA,RNA,protein等基本分子生物學知識。4. 細胞生物學 : 介紹細胞胞器 , 細胞分化 ,生長 , 細胞週期 , 細胞死亡等細胞特性。5. 毒理學 : 介紹毒理評估實驗設計 , 毒理機制等。6. 細胞訊息傳遞 : 介紹細胞內生長分化或細胞凋亡等訊息傳遞路徑。7. 腫瘤生物學 : 介紹腫瘤成因 , 腫瘤的分子機制等。8. 2003-2004 年 : 於嘉南藥理科技大學化妝品應用管理學系教授皮膚生理生化學必修三學分。9. 生物天然物 : 天然aquaculture未來研究計畫 :(1) 天然物預防及治療癌症的機制。(2) 天然物促進細胞老化以促進腫瘤細胞死亡的機轉研究。(3) 天然物作為癌症治療的致敏劑研究First author:6 (2009 年以後 4 篇 )1. Chen RJ, Hung CM, Chen YL, Wu MD, Yuan GF,Wang YJ. Monascuspiloin: A Monascin AnalogueInduces Apoptosis and Autophagic Cell Death inHuman Prostate Cancer Cells via the Akt and AMPKSignaling Pathways. 2012 (The Journal ofNutritional Biochemistry, submitted).2. Chen RJ, Ho YS, Wu CH, Wang YJ. MolecularMechanisms of Nicotine-induced Bladder Cancer.Journal of Experimental and Clinical Medicine. 3,252-256 (2011) (New Journal) (First author)3. Chen RJ, Chang LW, Lin P, Wang YJ. EpigeneticEffects and Molecular Mechanisms ofTumorigenesis Induced by Cigarette Smoke: AnOverview. Journal of Oncology, 654391, 14 pages,(2011) (New Journal) (First author)4. Chen RJ, Ho CT, Wang YJ. Pterostilbene inducesautophagy and apoptosis in sensitive andchemoresistant human bladder cancer cells.Molecular Nutrition & Food Research. 54,1819-1832 (2010)(SCI. IF= 4.713. rank: 1/126= 1%in Food Science & Technology, JCR 2010) (Firstauthor)5. Chen RJ, Ho YS, Guo HR, Wang YJ. Long-term台北醫學大學 / 國立成功大學臨床醫學研究所 / 環境醫學研究所博士後研究員(2011/08 ~迄今 )Taiwan

物分類、抗氧化、抗菌、抗腫瘤等功能。nicotine exposure-induced chemoresistance ismediated by activation of Stat3 and downregulationof ERK1/2 via nAChR and beta-adrenoceptors inhuman bladder cancer cells. Toxicological Sciences.115, 118-130 (2010)(SCI. IF= 5.093. rank: 3/86=3.5 % in Toxicology, JCR 2010) (First author)6. Chen RJ, Ho YS, Guo HR, Wang YJ. Rapidactivation of Stat3 and ERK1/2 by nicotinemodulates cell proliferation in human bladder cancercells. Toxicological Sciences. 104, 283-293(2008)(SCI. IF= 5.093. rank: 3/86= 3.5 % inToxicology, JCR 2010) (First author)7. Huang CS, Ho WL, Lee WS, Sheu MT, Wang YJ,Tu SH, Chen RJ, Chu JS, Chen LC, Lee CH, TsengH, Ho YS, Wu CH. SP1-regulated p27/Kip1 geneexpression is involved in terbinafine-induced humanA431 cancer cell differentiation: an in vitro and invivo study. Biochemical Pharmacology. 75,1783-96 (2008) (SCI. IF= 4.889. rank: 20/249= 8% in Pharmacology & Pharmacy, JCR 2010)8. Cheng TJ, Wang YJ, Kao WW, Chen RJ, Ho YS.Protection against arsenic trioxide-inducedautophagic cell death in U118 human glioma cellsby use of lipoic acid. Food and ChemicalToxicology. 45, 1027-38 (2007) (SCI. IF= 2.602.rank: 16/126= 12.7 % in Food Science &Technology, JCR 2010)9. Ho YS, Huang PC, Guo HR, Chang WH, Chen RJ.Wei BL, Wu WJ, Tai C, Wang YJ. Mechanisms of

apoptosis induction and cell cycle regulation inirradiated leukemia U937 cells and enhancement byarsenic trioxide. Radiation Research. 165, 390-9(2006) (SCI. IF= 2.578. rank: 21/85= 24.7 % inBiology, JCR 2010)10. Guo HR. Chen CH. Ho SY. Ho YS. Chen RJ.Wang YJ. Staurosporine modulates radiosensitivityand radiation-induced apoptosis in U937 cells.International Journal of Radiation Biology. 82,97-109 (2006) (SCI. IF= 1.861. rank: 2/34= 5.9 %in Nuclear Science & Technology, JCR 2010)11. Ho YS, Chen CH, Wang YJ, Pestell RG, AlbaneseC, Chen RJ. Chang MC, Jeng JH, Lin SY, LiangYC, Tseng H, Lee WS, Lin JK, Chu JS, Chen LC,Lee CH, Tso WL, Lai YC, Wu CH.Tobacco-specific carcinogen4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone(NNK) induces cell proliferation in normal humanbronchial epithelial cells through NFkappaBactivation and cyclin D1 up-regulation. Toxicology& Applied Pharmacology. 205, 133-48 (2005)(SCI.IF= 3.993. rank: 10/83= 12 % in Toxicology, JCR2010)12. Lee WS, Chen RJ, Wang YJ, Tseng H, Jeng JH,Lin SY, Liang YC, Chen CH, Lin CH, Lin JK, HoPY, Chu JS, Ho WL, Chen LC, Ho YS. In vitro andin vivo studies of the anticancer action of terbinafinein human cancer cell lines: G0/G1 p53-associatedcell cycle arrest. International Journal of Cancer.

106,:125-37 (2003)(SCI. IF= 4.926. rank: 32/184=17.4 % in Oncology, JCR 2010)13. Wang YJ, Jeng JH, Chen RJ, Tseng H, Chen LC,Liang YC, Lin CH, Chen CH, Chu JS, Ho WL, HoYS. Ketoconazole potentiates the antitumor effectsof nocodazole: In vivo therapy for human tumorxenografts in nude mice. MolecularCarcinogenesis. 34, 199-210 (2002)(SCI. IF=3.265. rank: 63/184= 34.2 % in Oncology, JCR2010)14. Ho YS, Duh JS, Jeng JH, Wang YJ, Liang YC,Lin CH, Tseng CJ, Yu CF, Chen RJ, Lin JK.Griseofulvin potentiates antitumorigenesis effects ofnocodazole through induction of apoptosis andG2/M cell cycle arrest in human colorectal cancercells. International Journal of Cancer. 91, 393-401( 2001) (SCI. IF= 4.926. rank: 32/184= 17.4 % inOncology, JCR 2010)15. Chen RJ, Lee WS, Liang YC, Lin JK, Wang YJ,Lin CH, Hsieh JY, Chaing CC, Ho YS.Ketoconazole induces G0/G1 arrest in humancolorectal and hepatocellular carcinoma cell lines.Toxicology & Applied Pharmacology. 169, 132-41(2000) (SCI. IF= 3.993. rank: 10/83= 12 % inToxicology, JCR 2010)(First author)16. Ho YS, Liu HL, Duh JS, Chen RJ, Ho WL, JengJH, Wang YJ, Lin JK. Induction of apoptosis byS-nitrosoglutathione and Cu2+ or Ni2+ ion throughmodulation of bax, bad, and bcl-2 proteins in human

colon adenocarcinoma cells. MolecularCarcinogenesis. 26, 201-11 (1999)(SCI. IF= 3.265.rank: 63/184= 34.2 % in Oncology, JCR 2010)17. Ho YS, Tsai PW, Yu CF, Liu HL, Chen RJ. LinJK. Ketoconazole-induced apoptosis throughP53-dependent pathway in human colorectal andhepatocellular carcinoma cell lines. Toxicology &Applied Pharmacology. 153, 39-47 (1998)(SCI.IF= 3.993. rank: 10/83= 12 % in Toxicology, JCR2010)20 李英瑞( 助理教授 )AGE:?國立成功大學醫學院基礎醫學研究所博士(2008/02)可教授課程科目 :普通微生物學(GeneralMicrobiology)、醫用微生物學(MedicalMicrobiology)、腫瘤生物學 (TumorBiology)、生物技術(Biotechnology)、海洋抗癌藥物開發(Marine Anti-CancerDrug Development),海洋天然物抗感染症藥物開發 (MarineAnti-InfectiousDisease DrugDevelopment)專長學門 :微生物學、病毒學、感染症學、細胞生物學、腫瘤生物學、細胞訊息傳遞、分子生物學First author:14 (2009 年以後 8 篇 ) — 已算入corresponding author 篇數1. Chieh-Hisang Lu, Shih-Che Hua, Hui-I Yu andYing-Ray Lee. Autophagy induction inreversine treated human follicular thyroidcancer cells. (Manuscript writting) (grant: NSC99-2314-B-705-002-MY2)2. Ying-Ray Lee, Hsuan-Yun Hu, Huan-Yao Lei,Yee-Shin Lin, Trai-Ming Yeh, Ching-Chuan Liu,and Hsiao-Sheng Liu. Autophagy induction invivo elevates clinical signs and viral replicationduring dengue virus infection. (Preparation forsubmitting)財團法人嘉義基督教醫院醫研部專任副研究員(2008/05迄今 )Taiwan3. Szu-Yuan Wu, Yi-Zhen Li, Shu-Hsin Chen andYing-Ray Lee. Irradiation induced autophagy inhuman oral squamous cell carcinoma.(Submitting) (corresponding author) (grant:NSC 99-2314-B-705-002-MY2)

4. Jin-Ho Guo, Shu-Hsin Chen, Ping-Tzu Chen,Yin-Che Lu, and Ying-Ray Lee. Evaluation of 2,6-disubstituted purine as an anti-cancercandidate in human breast cancer.(Submitting) (corresponding author) (grant:NSC 99-2314-B-705-002-MY2)5. Chia-Ching Chen, Yi-Wen Chen, Ying-ChiehLu, Wen-Li Lee, Chieh-Hsiang Lu, You-HsuanChen, Hsiu-Chuan Chou, John F. Timms,Ying-Ray Lee and Hong-Lin Chan. Hemopexinis up-regulated in plasma from type 1 diabetesmellitus patients role of glucose-induced ROS.(Submitting) (co-corresponding author) (grant:NSC 99-2314-B-705-002-MY2)6. Szu-Yuan Wu, Ying-Ray Lee, Yi-Zhen Li,Jiann-Der Wu, Yi-Sheng Chang, Chin-ChinHuang, and Yi-Wen Liu. 2011.Curcumin-induced heme oxygenase-1expression plays a negative role for anti-cancereffect of curcumin in bladder cancers. (Revised)7. Wen-Tsai Ji, Sheng-Ru Yang, Jeff Yi-Fu Chen,Ya-Ping Cheng, Ying-Ray Lee, Ming-KoChiang and Hau-Ren Chen. 2012. Arecolinedownregulates p21 and p27 via ROS/mTORC1pathway and may contribute to oral squamouscell carcinoma. Cancer Science (In Press)8. Shih-Che Hua, Hau-Ren Chen, Shu-Hsin Chen,Chieh-Hisang Lu, Hui-I Yu, Tien-Chun Changand Ying-Ray Lee. 2012. Reversine, a

2,6-disubstituted purine, as an anti-canceragent in differentiated and undifferentiatedthyroid cancer cells. Pharmaceutical Research(In Press)(corresponding author) (grant: NSC99-2314-B-705-002-MY2)9. Ying-Ray Lee, Wei-Ching Wu, Wen-Tsai Ji, JeffYi-Fu Chen, Ya-Ping Cheng, Ming-Ko Chiangand Hau-Ren Chen. 2012. Reversinesuppresses oral squamous cell carcinoma viacell cycle arrest and concomitantly apoptosisand autophagy. Journal of Biomedical Science19, 9-20.10. Chao-Po Lin, Yi-Wen Chen, Wen-Hsin Liu,Hsiu-Chuan Chou,Yi-Ping Chang, Szu-TingLin, Ji-Min Li, Shiou-Fen Jian, Ying-Ray Leeand Hong-Lin Chan. 2012. Proteomicidentification of plasma biomarkers in uterineleiomyoma. Molecular BioSystems 8, 1136-1145.(co-corresponding author)11. Cheng-Huang Shen, Jiann-Der Wu,Yeong-Chin Jou, Ming-Chin Cheng, Chang-TeLin, Pi-Che Chen, Ya-Shih Tseng,Chung-Sheng Shi, Syue-Yi Chen, De-ChingChang, and Ying-Ray Lee. 2011. Thecorrelation between Twist, E-cadherin andbeta-catenin in human bladder cancer. Journalof BUON 16, 733-737. (corresponding author)(grant: NSC 99-2314-B-705-002-MY2)12. Shan-Ying Wu, Shan-Ying Wu, Sheng-Hui

Lan, Da-En Cheng, Wei-Kai Chen,Cheng-Huang Shen, Ying-Ray Lee, RobertoZuchini and Hsiao-Sheng Liu. 2011.Ras-related tumorigenesis is suppressed byBNIP3-mediated autophagy through inhibitionof cell proliferation. Neoplasia 13, 1171-1182.13. Wei-Ying Hsieh, Mei-Yi Lin, I-An Huang,Syue-Yi Chen, Shu-Hsin Chen, Yi-Ping Chang,Ying-Ray Lee. 2011. Evaluation of traditionalChinese medicine on EV71 nucleic acidtranslation regulation. Journal of Chinese WestMedicine 13, 1-12. (co-corresponding author)14. Peir-Haur Hung, Yi-Wen Chen, Kuang-ChiCheng, Hsiu-Chuan Chou, Ying-Chieh Lu,Ying-Ray Lee, Cheng-Tao Wu and Hong-LinChan. 2011. Plasma Proteomic Analysis of theCritical Limb Ischemia Markers in DiabeticPatients with Hemodialysis. MolecularBioSystems 7, 1990-1998. (co-correspondingauthor)15. Peir-Haur Hung, Ying-Chieh Lu, Yi-Wen Chen,Hsiu-Chuan Chou, Ping-Chiang Lyu, Ying-RayLee, and Hong-Lin Chan. 2011. Proteomicidentification of plasma signatures in type 2diabetic nephropathy. Journal of IntegratedOMICS 1, 151-156. (co-corresponding author)16. Shih-Che Hua, Syue-Yi Chen, Chieh-HisangLu, Yu-Ting Kao, Hui-I Yu, Ping-Tzu Chen,Tien-Chun Chang and Ying-Ray Lee. 2010.

The effects of growth inhibitory peptide onfollicular thyroid cancer cell growth, migration,and invasion. Tumori 96, 448-451.(corresponding author) (grant: NSC98-2320-B-705-001)17. Lee, Y. R., Lei, H. Y., Wang, J. R., Chen, S. H.,Jiang-Shieh, Y. F., Lin, Y. S., Yeh, T. M., Liu, C.C. and Liu, H. S. 2008. Autophagic machineryactivated by dengue virus enhances virusreplication. Virology 374, 240-248.18. Lee, Y. R., Lei, H. Y., Chen, S. H., Wang, J. R.,Lin, Y. S., Yeh, T. M., Liu, C. C. and Liu, H.S.2008. Signaling pathways involved in dengue-2virus infection inducedRANTESover-expression. Americ. J. Infect.Dis., 4, 32-40.19. Lee, Y. R., Hung, N. T., Liu, C. C., Huang, K. J.,Lei, H. Y., Lin, Y. S., Wang, J. R., Yeh, T. M.,Chen, S. H., and Liu, H. S. 2008. Correlation ofIFN-inducible protein 10 levels in sera withdisease severity and clinical outcome of thedengue patients. Americ. J. Infect. Dis., 4,18-21.20. Lee, Y. R., Su, C. Y., Chow, N. H., Lai, W. W.,Lei, H. Y., Chang, C. L., Chang, T. Y., Chen, S.H., Lin, Y. S., Yeh, T. M., and Liu, H. S. 2007.Dengue viruses can infect human primary lungepithelia as well as lung carcinoma cells, andcan also induce the secretion of IL-6 and

RANTES. Virus Res. 126, 216-225.21. Lee, Y. R., Liu, M. T., Lei, H. Y., Liu, C. C., Wu,J. M., Tung, Y. C. Lin, Y. S., Yeh, T. M., Chen,S. H., and Liu, H. S. 2006. MCP-1, a highlyexpressed chemokine in dengue haemorrhagicfever/dengue shock syndrome patients, maycause permeability change, possibly throughreduced tight junctions of vascular endotheliumcells. J Gen Virol. 87, 3623-3630.22. Lee, Y. R., Huang, K. J., Lei, H. Y., Chen, S.H., Lin, Y. S., Yeh, T. M., and Liu, H. S. 2005.Establishment of a suckling mice system toscreen and produce infectious dengue-2viruses from full-length cDNA. Intervirology 48,161-166.

國立中山大學海洋生物科技暨資源學系「五學年學、碩士」學位辦法中華民國 88 年 11 月 26 日八十八學年度第六次系務會議訂定中華民國 100 年 3 月 18 日九十九學年度第四次系務會議修正通過中華民國 100 年 12 月 19 日第 130 次教務會議修正通過中華民國 101 年 4 月 16 日 100 學年度第八次系務會議修正通過第一條為鼓勵本校大學部優秀學生就讀本系碩士班 , 特訂定本辦法。第二條錄取名額 : 八名。第三條相關系所之定義 : 本校理、工、海洋學院各學系。第四條甄選辦法 : 資料審查1、在該系前五學期之平均成績為班上前 50%。2、修業滿五學期之歷年成績單正本。3、其他有助審查之相關資料。第五條錄取之學生具備本系碩士班預備研究生 ( 預研生 ) 資格。第六條本辦法經系 ( 所 ) 務會議 , 教務會議通過 , 經校長核定後實施 , 修正時亦同。

含簽名及附件-簡式 - 海洋生物科技暨資源學系- 國立中山大學

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