13.07.2015 Views

New roles of osteoblasts involved in osteoclast differentiation

New roles of osteoblasts involved in osteoclast differentiation

New roles of osteoblasts involved in osteoclast differentiation

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Yamashita T et al . Osteoblasts and <strong>osteoclast</strong> <strong>differentiation</strong>7 Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, BurgessT, Elliott R, Colombero A, Elliott G, Scully S, Hsu H,Sullivan J, Hawk<strong>in</strong>s N, Davy E, Capparelli C, Eli A, QianYX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, DelaneyJ, Boyle WJ. Osteoproteger<strong>in</strong> ligand is a cytok<strong>in</strong>e thatregulates <strong>osteoclast</strong> <strong>differentiation</strong> and activation. Cell 1998;93: 165-1768 Takayanagi H, Kim S, Koga T, Nish<strong>in</strong>a H, Isshiki M, YoshidaH, Saiura A, Isobe M, Yokochi T, Inoue J, Wagner EF,Mak TW, Kodama T, Taniguchi T. Induction and activation<strong>of</strong> the transcription factor NFATc1 (NFAT2) <strong>in</strong>tegrateRANKL signal<strong>in</strong>g <strong>in</strong> term<strong>in</strong>al <strong>differentiation</strong> <strong>of</strong> <strong>osteoclast</strong>s.Dev Cell 2002; 3: 889-9019 Simonet WS, Lacey DL, Dunstan CR, Kelley M, ChangMS, Lüthy R, Nguyen HQ, Wooden S, Bennett L, BooneT, Shimamoto G, DeRose M, Elliott R, Colombero A, TanHL, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Gegg L,Hughes TM, Hill D, Pattison W, Campbell P, Sander S, VanG, Tarpley J, Derby P, Lee R, Boyle WJ. Osteoproteger<strong>in</strong>: anovel secreted prote<strong>in</strong> <strong><strong>in</strong>volved</strong> <strong>in</strong> the regulation <strong>of</strong> bonedensity. Cell 1997; 89: 309-31910 Yasuda H, Shima N, Nakagawa N, Mochizuki SI, YanoK, Fujise N, Sato Y, Goto M, Yamaguchi K, Kuriyama M,Kanno T, Murakami A, Tsuda E, Mor<strong>in</strong>aga T, Higashio K.Identity <strong>of</strong> <strong>osteoclast</strong>ogenesis <strong>in</strong>hibitory factor (OCIF) andosteoproteger<strong>in</strong> (OPG): a mechanism by which OPG/OCIF<strong>in</strong>hibits <strong>osteoclast</strong>ogenesis <strong>in</strong> vitro. Endocr<strong>in</strong>ology 1998; 139:1329-133711 Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, CapparelliC, Morony S, Oliveira-dos-Santos AJ, Van G, Itie A, Khoo W,Wakeham A, Dunstan CR, Lacey DL, Mak TW, Boyle WJ,Penn<strong>in</strong>ger JM. OPGL is a key regulator <strong>of</strong> <strong>osteoclast</strong>ogenesis,lymphocyte development and lymph-node organogenesis.Nature 1999; 397: 315-32312 Li J, Sarosi I, Yan XQ, Morony S, Capparelli C, Tan HL, Mc-Cabe S, Elliott R, Scully S, Van G, Kaufman S, Juan SC, SunY, Tarpley J, Mart<strong>in</strong> L, Christensen K, McCabe J, KostenuikP, Hsu H, Fletcher F, Dunstan CR, Lacey DL, Boyle WJ.RANK is the <strong>in</strong>tr<strong>in</strong>sic hematopoietic cell surface receptorthat controls <strong>osteoclast</strong>ogenesis and regulation <strong>of</strong> bone massand calcium metabolism. Proc Natl Acad Sci USA 2000; 97:1566-157113 Bucay N, Sarosi I, Dunstan CR, Morony S, Tarpley J, CapparelliC, Scully S, Tan HL, Xu W, Lacey DL, Boyle WJ, SimonetWS. osteoproteger<strong>in</strong>-deficient mice develop early onsetosteoporosis and arterial calcification. Genes Dev 1998; 12:1260-126814 Mizuno A, Amizuka N, Irie K, Murakami A, Fujise N, KannoT, Sato Y, Nakagawa N, Yasuda H, Mochizuki S, GomibuchiT, Yano K, Shima N, Washida N, Tsuda E, Mor<strong>in</strong>aga T,Higashio K, Ozawa H. Severe osteoporosis <strong>in</strong> mice lack<strong>in</strong>g<strong>osteoclast</strong>ogenesis <strong>in</strong>hibitory factor/osteoproteger<strong>in</strong>. BiochemBiophys Res Commun 1998; 247: 610-61515 Cundy T, Hegde M, Naot D, Chong B, K<strong>in</strong>g A, Wallace R,Mulley J, Love DR, Seidel J, Fawkner M, Banovic T, CallonKE, Grey AB, Reid IR, Middleton-Hardie CA, Cornish J. Amutation <strong>in</strong> the gene TNFRSF11B encod<strong>in</strong>g osteoproteger<strong>in</strong>causes an idiopathic hyperphosphatasia phenotype. HumMol Genet 2002; 11: 2119-212716 Chong B, Hegde M, Fawkner M, Simonet S, Cass<strong>in</strong>elli H,Coker M, Kanis J, Seidel J, Tau C, Tüysüz B, Yüksel B, LoveD. Idiopathic hyperphosphatasia and TNFRSF11B mutations:relationships between phenotype and genotype. JBone M<strong>in</strong>er Res 2003; 18: 2095-210417 Whyte MP, Obrecht SE, F<strong>in</strong>negan PM, Jones JL, PodgornikMN, McAlister WH, Mumm S. Osteoproteger<strong>in</strong> deficiencyand juvenile Paget’s disease. N Engl J Med 2002; 347: 175-18418 Hughes AE, Ralston SH, Marken J, Bell C, MacPherson H,Wallace RG, van Hul W, Whyte MP, Nakatsuka K, HovyL, Anderson DM. Mutations <strong>in</strong> TNFRSF11A, affect<strong>in</strong>g thesignal peptide <strong>of</strong> RANK, cause familial expansile osteolysis.Nat Genet 2000; 24: 45-4819 Guerr<strong>in</strong>i MM, Sobacchi C, Cassani B, Ab<strong>in</strong>un M, Kilic SS,Pangrazio A, Moratto D, Mazzolari E, Clayton-Smith J,Orchard P, Coxon FP, Helfrich MH, Crockett JC, Mellis D,Vellodi A, Tezcan I, Notarangelo LD, Rogers MJ, VezzoniP, Villa A, Fratt<strong>in</strong>i A. Human <strong>osteoclast</strong>-poor osteopetrosiswith hypogammaglobul<strong>in</strong>emia due to TNFRSF11A (RANK)mutations. Am J Hum Genet 2008; 83: 64-7620 Sobacchi C, Fratt<strong>in</strong>i A, Guerr<strong>in</strong>i MM, Ab<strong>in</strong>un M, PangrazioA, Susani L, Bredius R, Manc<strong>in</strong>i G, Cant A, Bishop N,Grabowski P, Del Fattore A, Mess<strong>in</strong>a C, Errigo G, CoxonFP, Scott DI, Teti A, Rogers MJ, Vezzoni P, Villa A, HelfrichMH. Osteoclast-poor human osteopetrosis due to mutations<strong>in</strong> the gene encod<strong>in</strong>g RANKL. Nat Genet 2007; 39: 960-96221 Mizoguchi T, Muto A, Udagawa N, Arai A, YamashitaT, Hosoya A, N<strong>in</strong>omiya T, Nakamura H, Yamamoto Y,K<strong>in</strong>ugawa S, Nakamura M, Nakamichi Y, Kobayashi Y, NagasawaS, Oda K, Tanaka H, Tagaya M, Penn<strong>in</strong>ger JM, Ito M,Takahashi N. Identification <strong>of</strong> cell cycle-arrested quiescent<strong>osteoclast</strong> precursors <strong>in</strong> vivo. J Cell Biol 2009; 184: 541-55422 Muto A, Mizoguchi T, Udagawa N, Ito S, Kawahara I,Abiko Y, Arai A, Harada S, Kobayashi Y, Nakamichi Y, Penn<strong>in</strong>gerJM, Noguchi T, Takahashi N. L<strong>in</strong>eage-committed<strong>osteoclast</strong> precursors circulate <strong>in</strong> blood and settle down <strong>in</strong>tobone. J Bone M<strong>in</strong>er Res 2011; 26: 2978-299023 L<strong>in</strong> H, Lee E, Hestir K, Leo C, Huang M, Bosch E, HalenbeckR, Wu G, Zhou A, Behrens D, Hollenbaugh D, L<strong>in</strong>nemann T,Q<strong>in</strong> M, Wong J, Chu K, Doberste<strong>in</strong> SK, Williams LT. Discovery<strong>of</strong> a cytok<strong>in</strong>e and its receptor by functional screen<strong>in</strong>g <strong>of</strong>the extracellular proteome. Science 2008; 320: 807-81124 Chihara T, Suzu S, Hassan R, Chutiwitoonchai N, HiyoshiM, Motoyoshi K, Kimura F, Okada S. IL-34 and M-CSF sharethe receptor Fms but are not identical <strong>in</strong> biological activityand signal activation. Cell Death Differ 2010; 17: 1917-192725 Chen Z, Buki K, Vääräniemi J, Gu G, Väänänen HK. Thecritical role <strong>of</strong> IL-34 <strong>in</strong> <strong>osteoclast</strong>ogenesis. PLoS One 2011; 6:e1868926 Nakamichi Y, Mizoguchi T, Arai A, Kobayashi Y, SatoM, Penn<strong>in</strong>ger JM, Yasuda H, Kato S, DeLuca HF, Suda T,Udagawa N, Takahashi N. Spleen serves as a reservoir <strong>of</strong><strong>osteoclast</strong> precursors through vitam<strong>in</strong> D-<strong>in</strong>duced IL-34expression <strong>in</strong> osteopetrotic op/op mice. Proc Natl Acad SciUSA 2012; 109: 10006-1001127 Ishii M, Egen JG, Klauschen F, Meier-Schellersheim M,Saeki Y, Vacher J, Proia RL, Germa<strong>in</strong> RN. Sph<strong>in</strong>gos<strong>in</strong>e-1-phosphate mobilizes <strong>osteoclast</strong> precursors and regulatesbone homeostasis. Nature 2009; 458: 524-52828 Arai A, Mizoguchi T, Harada S, Kobayashi Y, NakamichiY, Yasuda H, Penn<strong>in</strong>ger JM, Yamada K, Udagawa N, TakahashiN. Fos plays an essential role <strong>in</strong> the upregulation <strong>of</strong>RANK expression <strong>in</strong> <strong>osteoclast</strong> precursors with<strong>in</strong> the bonemicroenvironment. J Cell Sci 2012; 125: 2910-291729 Maeda K, Kobayashi Y, Udagawa N, Uehara S, Ishihara A,Mizoguchi T, Kikuchi Y, Takada I, Kato S, Kani S, Nishita M,Marumo K, Mart<strong>in</strong> TJ, M<strong>in</strong>ami Y, Takahashi N. Wnt5a-Ror2signal<strong>in</strong>g between osteoblast-l<strong>in</strong>eage cells and <strong>osteoclast</strong>precursors enhances <strong>osteoclast</strong>ogenesis. Nat Med 2012; 18:405-41230 Gordon MD, Nusse R. Wnt signal<strong>in</strong>g: multiple pathways,multiple receptors, and multiple transcription factors. J BiolChem 2006; 281: 22429-2243331 Gong Y, Slee RB, Fukai N, Rawadi G, Roman-Roman S, Reg<strong>in</strong>atoAM, Wang H, Cundy T, Glorieux FH, Lev D, Zachar<strong>in</strong>M, Oexle K, Marcel<strong>in</strong>o J, Suwairi W, Heeger S, Sabatakos G,Apte S, Adk<strong>in</strong>s WN, Allgrove J, Arslan-Kirchner M, BatchJA, Beighton P, Black GC, Boles RG, Boon LM, Borrone C,Brunner HG, Carle GF, Dallapiccola B, De Paepe A, FloegeB, Halfhide ML, Hall B, Hennekam RC, Hirose T, Jans A,Jüppner H, Kim CA, Keppler-Noreuil K, Kohlschuetter A,WJO|www.wjgnet.com180 November 18, 2012|Volume 3|Issue 11|

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!