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Lecture 6 SKIN (Integumentary System) Definition: The skin or ...

Lecture 6 SKIN (Integumentary System) Definition: The skin or ...

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Clinical Considerations:<br />

4. Clinical Considerations:<br />

Hyperkeratosis: hypertrophy of the stratum c<strong>or</strong>neum<br />

[nasodigital hyperkeratosis - an ailment affecting either the<br />

nose <strong>or</strong> foot pads (<strong>or</strong> both) of older dogs. In<br />

hyperkeratosis, keratin - the tough, fibrous outer covering<br />

of foot pads - grows excessively. Often, the hard, cracked<br />

pads appear to have "keratin feathers" around their<br />

edges.]<br />

Squamous Cell Carcinoma: neoplasia of cells of the<br />

stratum spinosum [Squamous cell carcinoma (SCC) is a<br />

common tum<strong>or</strong> involving the <strong>skin</strong> and a ccounts f<strong>or</strong><br />

approximately 15% of cutaneous tum<strong>or</strong>s in the cat and 5%<br />

of those in the dog. SCCs are usually found in<br />

unpigmented <strong>or</strong> lightly pigmented <strong>skin</strong>.]<br />

. Melanoma: Melanocytic tum<strong>or</strong>s represent 4 to 7% of a ll<br />

canine neoplasms and are the most common malignant<br />

tum<strong>or</strong> of the canine <strong>or</strong>al cavity and digits [Melanoma<br />

tum<strong>or</strong>s in dogs, m<strong>or</strong>e than most cancers, demand<br />

immediate attention since early recognition can lead to<br />

m<strong>or</strong>e successful attempts at removal and identification of<br />

the grade <strong>or</strong> stage of cancer. Malignant melanomas can<br />

metastasize (spread) to any area of the body especially<br />

the lymph nodes and lungs and present very challenging<br />

and dangerous prospects f<strong>or</strong> the dog. Cats seem much<br />

less susceptible to melanoma tum<strong>or</strong>s than dogs]<br />

1.

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