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Strategic Nutrition for Bone and Joint Health - Fortitech

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PAGE 2CalciumCalcium is an important constituent of bone, but is also needed in the body <strong>for</strong> proper functioningof the heart, muscles, nerves, <strong>and</strong> in blood clotting. A low intake of calcium, whichis common with most people, contributes to bone loss <strong>and</strong> the development of low bonemass <strong>and</strong> osteoporosis – a skeletal condition affecting 44 million people in the US alone –that results in an increased risk of bone fractures, especially of the hip, spine <strong>and</strong> wrist.<strong>Bone</strong> loss also contributes to loss of teeth due to erosion of the underlying boney anchor ofthe tooth’s root. Tooth loss affects about one-third of adults age 65 <strong>and</strong> older. Currentrecommended intakes of calcium are between 1,000-1,300 mg/day depending on age,which is about twice the level of usual calcium intakes.Explore related news<strong>and</strong> research on bone<strong>and</strong> joint health onour TweetDeck atwww.twitter.com/<strong>for</strong>titechVitamin DVitamin D is needed by the body to facilitate the intestinal absorptionof calcium, as well as <strong>for</strong> other important body functions.Un<strong>for</strong>tunately, vitamin D deficiency is common throughout theworld, <strong>and</strong> contributes to poor bone health, especially when dietarycalcium intakes are low. It is estimated that one in five children,aged one to 11 years old don’t get enough vitamin D.Prevalence rates <strong>for</strong> vitamin D insufficiency in black <strong>and</strong> Hispanicchildren are, alarmingly, much higher. The current recommendeddietary vitamin D intake is 5µg to 15µg (200-600 IU) per day.However, considerable disagreement over the adequacy of thisrecommendation has ensued in light of recent research findings,<strong>and</strong> some prominent vitamin D researchers are suggesting that 50µg (2,000 IU) per daymay be a more reasonable level of vitamin D intake to promote optimal bone health. Productsdesigned to deliver calcium should also provide vitamin D because these two nutrientswork together in order to provide the best opportunity <strong>for</strong> calcium to be absorbed into thebody.Vitamin KVitamin K is well known <strong>for</strong> its important role in blood clotting. However, research in recentyears has suggested that vitamin K may play an important role in maintaining bone health<strong>and</strong> reducing the risk of osteoporotic bone fracture in the elderly. Natural vitamin K in thefood supply is found in two <strong>for</strong>ms, vitamin K 1 (phylloquinone) in plant foods <strong>and</strong> vitamin K 2(menaquinone) in animal foods or produced by bacteria, with vitamin K 1 being slightly moreactive biologically than vitamin K 2 . The recommended intakes of vitamin K is 120µg/day inmen, <strong>and</strong> slightly lower in women, with intakes as high as 400-500µg/day being suggestedto influence bone metabolism. However, some very recent clinical trials of vitamin K supplementationin elderly postmenopausal women have found no effect of additional vitaminK on rates of bone loss during a three-year trial. These findings are difficult to interpret,however, because subjects were generally healthy <strong>and</strong> not selected on the basis of preexistinglow vitamin K status. Given the strong epidemiologic evidence that high vitamin Kintake is associated with reduced risk of osteoporotic fracture, it would be prudent to includevitamin K as an important nutrient in any bone-protecting <strong>for</strong>tified product.Vitamin CHigher intakes of fruits <strong>and</strong> vegetables have been associated with higher bone mineral densityin cross-sectional population studies. Investigators in the United Kingdom found thathigher vitamin C intake in adolescent boys <strong>and</strong> girls, young women, <strong>and</strong> older men <strong>and</strong>women are associated with bone mineral content. Research in the US found in the PostmenopausalEstrogen/Progestin Intervention Trial (PEPI Study) that higher vitamin C intakeSTRATEGIC NUTRITION FOR BONE & JOINT HEALTHTECHNICAL PAPER—JAN, 2010PAGE 5

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