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JMEN (ma<strong>in</strong>tenance pemetrexed):PFS and OS <strong>in</strong> ITT populationPatients with stage IIIB/IV<strong>NSCLC</strong> and PS 0–1 who hadreceived 4 previous cycles ofgemcitab<strong>in</strong>e, docetaxel, orpaclitaxel + plat<strong>in</strong>um with CR, PR,or SD (n=663)RANDOMISE2:1Pemetrexed 500mg/m 2 on d1q21d + BSC(n=441)Placebo on d1 q21d + BSC(n=222)PFS probability1.00.80.60.40.2PemetrexedPlaceboHR=0.60 (95% CI 0.49–0.73);p