G2 (1) Metabolic syndrome

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OBJECTIVES• Definition and diagnosis• Pathophysiology: Insulin Resistance• Clinical significance and implications• Prevalence: MSSM study and MetS inPenisular Malaysia.• Management of MetS
DefinitionA constellation of metabolic risk factors that consist of• Atherogenic dyslipidemia ( raised TG, apo B, smallLDLparticles plus low HDL cholesterol)• Elevated blood pressure• Elevated glucose associated with insulin resistance• Prothrombotic state• Proinflammatory state• Many of these factors require special testing, and notmeasured in clinical practice
Page 4 and 5: Diagnosis• The National Cholester
Page 6 and 7: Third Report of the Expert Panel on
Page 8 and 9: International Diabetes Federation (
Page 10 and 11: WHO definition of IRS, 1999AT LEAST
Page 12 and 13: DEFINITIONS OF METABOLIC SYNDROMERi
Page 14 and 15: OBJECTIVES• Definition and diagno
Page 16 and 17: • Adipocyte derives hormones call
Page 18 and 19: Clinical importance of MSPresence o
Page 20 and 21: Impact of the Metabolic Syndrome on
Page 22 and 23: Metabolic Syndrome: Total and CV Mo
Page 26 and 27: HARMONIZING THE METABOLIC SYNDROME.
Page 28 and 29: SOCIODEMOGRAPHIC CHARACTERISTICS OF
Page 30 and 31: Prevalence (%)PREVALENCE OF METABOL
Page 32 and 33: Prevalence (%)PREVALENCE OF METABOL
Page 34 and 35: MetS - where is Malaysiacompared to
Page 36 and 37: Prevalence of MetS in other populat
Page 38 and 39: Status of Diabetes Mellitus inMalay
Page 42 and 43: Cardiovascular Risk Reducing Treatm
Page 44 and 45: LIFE STYLE MODIFICATIONS WORKS• P
Page 46 and 47: MET-hours/weekHbA1c (%): placebo: M
Page 48: LIPIDSRisk FactorsLDL-cholesterolRe
Page 52 and 53:
Cardiovascular Risk Reducing Treatm
Page 54 and 55:
CONCLUSIONS• Definition and diagn
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G2 (1) Metabolic syndrome

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