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guidance

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When is pharmacological VTE preventionimpractical or contraindicated?Do not offer pharmacological VTE prophylaxis if patient has anyrisk factor for bleeding and risk of bleeding outweighs risk of VTEWho is at risk of bleeding?All patients who have any of the following:Concurrent use ofanticoagulants knownto increase the riskof bleeding (such aswarfarin with INR > 2)Thrombocytopenia(platelets < 75 x 109/l)Active bleedingAcute strokeAcquired bleedingdisorders (such asacute liver failure)Uncontrolledsystolic hypertension(≥ 230/120 mmHg)Lumbar puncture /epidural / spinalanaesthesia withinthe previous 4 hoursor expected withinthe next 12 hoursUntreated inheritedbleeding disorders (suchas haemophilia or vonWillebrand’s disease)

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