Application for the inclusion of Aciclovir eye ointment in the WHO list ...

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49. Yeakley WR, Laibson PR, Michelson MA, Arentsen JJ. A double-controlled evaluation of acyclovir and vidarabine for the treatment of herpes simplex epithelial keratitis. Trans Am Ophthalmol Soc 1981;79:168-79. 50. Young B, Patterson A, Ravenscroft T. Double-blind clinical trial of acyclovir and adenine arabinoside in herpetic corneal ulceration. Am J Med 1982;73(1A):311-2. 14
APPENDIX Table 1. Studies including acyclovir eye ointment that were included in the Cochrane Systematic Review Study author Treatments evaluated Number of patients enrolled Abe 1987 19 ACV Idoxuridine Altinisik 1987 20 ACV Idoxuridine Carmassi 1993 21 ACV Interferon Cellini 1994 22 ACV ACV + Epidermal growth factor Colin 1981 23 ACV Idoxuridine Colin 1983 24 ACV ACV + Interferon Colin 1984 25 ACV Iododeoxycytidine Colin 1987 26 ACV ACV + Vidarabine Colin 1997a 27 ACV Ganciclovir Colin 1997b 27 ACV Ganciclovir Collum 1980 28 ACV Idoxuridine Collum 1985 29 ACV Vidarabine Collum 1986 30 ACV Placebo Coster 1980 31 ACV Idoxuridine De Koning 1983 32 ACV ACV + Interferon Denis 1983 33 ACV Vidarabine Genee 1987 34 ACV Vidarabine Hoang-Xuan 1984 35 ACV Trifluridine Hoh 1996 36 ACV Ganciclovir 27 19 15 40 46 45 32 32 59 37 60 51 56 59 51 23 28 29 46 15
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