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Code Blue Teams in general hospital. Guidelines and best practices

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National & Kapodistrian University of Athens<br />

MEDICAL SCHOOL<br />

POST-GRADUATE PROGRAMME<br />

«International Medic<strong>in</strong>e – Health Crisis Management»<br />

ESSAY<br />

SUBJECT:<br />

« <strong>Code</strong> <strong>Blue</strong> <strong>Teams</strong> <strong>in</strong> <strong>general</strong> <strong>hospital</strong>. Guidel<strong>in</strong>es <strong>and</strong> <strong>best</strong> <strong>practices</strong>»<br />

POST-GRADUATE STUDENT:<br />

THEONI ZOUGOU<br />

ATHENS<br />

May, 2012


CONTENTS<br />

ENGLISH ABSTRACT -4-<br />

GREEK ABSTRACT -4-<br />

INTRODUCTION -5-<br />

CHAPTER 1 CARDIOPULMUNARY RESUSCITATION (CPR) -7-<br />

1.1 General Information - Def<strong>in</strong>itions -7-<br />

1.2 Cardiac Arrest Epidemiology -7-<br />

1.3 Predispos<strong>in</strong>g Factors of Cardiac Arrest -8-<br />

CHAPTER 2 FUNCTIONAL PRINCIPLES & AIMS OF CODE BLUE TEAM (CBT) IN<br />

HOSPITAL<br />

2.1 Activation <strong>and</strong> Call<strong>in</strong>g Criteria of CBT -9-<br />

2.2 Structure <strong>and</strong> roles <strong>in</strong> CBT -11-<br />

2.3 Assessment of CPR from CBT -11-<br />

2.4 Data Documentation <strong>and</strong> Record Keep<strong>in</strong>g -12-<br />

CHAPTER 3 STAFF TRAINING FOR IMMEDIATE CALL OF CBT -13-<br />

3.1 Tra<strong>in</strong><strong>in</strong>g on CPR <strong>and</strong> Affect<strong>in</strong>g Factors -13-<br />

3.2 Aggravat<strong>in</strong>g <strong>and</strong> Support<strong>in</strong>g Factors for early call of CBT -14-<br />

CHAPTER 4 LITERATURE REVIEW FOR CBT IN HOSPITALS -15-<br />

4.1 International Data -15-<br />

4.2 National Data -19-<br />

CONCLUSIONS -20-<br />

APPENDIX -21-<br />

BIBLIOGRAPHY -32-<br />

-9-<br />

2


ACKNOWLEDGMENTS<br />

I am particularly grateful to my colleaques Karapanou Amalia, Sampani Michael, Hatzopoulou Maria,<br />

Hatzopoulou Eir<strong>in</strong>i, who was so supportive by provid<strong>in</strong>g valuable data <strong>and</strong> <strong>in</strong>formation, dur<strong>in</strong>g the writ<strong>in</strong>g of<br />

these essay.<br />

3


ABSTRACT<br />

It has been estimated that the <strong>in</strong>cidence of <strong>in</strong>-<strong>hospital</strong> arrests is about 1-5/1000 admissions. The health care<br />

team has to deal with cardiac arrest <strong>in</strong> m<strong>in</strong>utes. If CPR is not implemented with<strong>in</strong> 3-4 m<strong>in</strong>utes, bra<strong>in</strong> disorder<br />

starts <strong>and</strong> leads to irreversible bra<strong>in</strong> damage.<br />

The term <strong>Code</strong> <strong>Blue</strong> is used to <strong>in</strong>dicate that a patient has an immediate need for resuscitation <strong>in</strong> order to<br />

prevent an arrest <strong>and</strong> call <strong>Code</strong> <strong>Blue</strong> Team through telephone.<br />

The code blue team is consisted of specific professionals, each professional knows his role, responds to<br />

every call <strong>and</strong> applies <strong>in</strong>ternational protocols.<br />

In Europe, America, Canada, Australia, the blue code is implemented successfully. In Greece, public<br />

<strong>hospital</strong>s are not implement<strong>in</strong>g the blue code only a few private <strong>hospital</strong>s do.<br />

KEYWORDS: <strong>Blue</strong> <strong>Code</strong>, cardiac arrest, cardiopulmonary resuscitation, resuscitation team<br />

ΠΕΡΙΛΗΨΗ<br />

Έχει υπολογιστεί ότι η συχνότητα των ενδονοσοκομειακών ανακοπών είναι περίπου 1-5/1000 εισαγωγές .<br />

Για να αντιμετωπισθεί η Καρδιακή Ανακοπή ο χρόνος κυμαίνεται σε ελάχιστα λεπτά. Αν δεν εφαρμοστεί<br />

Καρδιοαναπνευστική Αναζωογόνηση μέσα στα 3-4 λεπτά αρχίζει εγκεφαλική διαταραχή η οποία καταλήγει<br />

σε μη αναστρέψιμη εγκεφαλική βλάβη.<br />

Ο όρος Μπλε Κωδικός χρησιμοποιείται για να δείξει ότι ένας ασθενής έχει άμεση ανάγκη για αναζωογόνηση<br />

με σκοπό την πρόληψη μιας ανακοπής και κλήση της ομάδας του μπλε κωδικού μέσω δεκτών ειδοποίησης.<br />

Η ομάδα του μπλε κωδικού αποτελείται από συγκεκριμένα άτομα , το κάθε άτομο γνωρίζει το ρόλο του ,<br />

απάντά σε κάθε κλήση και εφαρμόζει τα διεθνή πρωτόκολλα.<br />

Στην Ευρώπη, στην Αμερική, στον Καναδά ,στην Αυστραλία ο μπλε κωδικός εφαρμόζεται με μεγάλη<br />

επιτυχία.<br />

Στην Ελλάδα στα δημόσια νοσοκομεία δεν γίνεται εφαρμογή του μπλε κωδικού παρά μόνο σε ελάχιστα<br />

ιδιωτικά νοσοκομεία .<br />

ΛΕΞΕΙΣ ΚΛΕΙΔΙΑ: Μπλε Κωδικός, Καρδιακή Ανακοπή, Καρδιοαναπνευστική Αναζωογόνηση, ομάδα<br />

αναζωογόνησης<br />

4


INTRODUCTION<br />

Ischemic heart disease is the lead<strong>in</strong>g cause of death worldwide. In Europe, cardiovascular diseases account<br />

for 40% of deaths <strong>in</strong> age groups up to 75 years. The sudden cardiac death is responsible for over 60% of<br />

adult deaths from coronary heart disease. Data from 37 European countries suggest that the annual <strong>in</strong>cidence<br />

of outpatient cardiac arrests treated by pre-<strong>hospital</strong> systems of immediate aid amount<strong>in</strong>g to 38 cases per<br />

100,000 <strong>in</strong>habitants. On the same basis, the annual <strong>in</strong>cidence of ventricular fibrillation (VF) treated by pre-<br />

<strong>hospital</strong> immediate aid systems is about 17 per 100,000 <strong>in</strong>habitants.<br />

The survival rate <strong>and</strong> discharge from the <strong>hospital</strong> is 10.7% for cardiac arrest from all cardiac rhythms<br />

<strong>and</strong> 21.2% for cardiac arrest from VF. These rates vary across cont<strong>in</strong>ents. On the other h<strong>and</strong>, the <strong>in</strong>cidence<br />

of <strong>hospital</strong> cardiac arrest is estimated with difficulty, because it is heavily <strong>in</strong>fluenced by factors such as: the<br />

criteria for <strong>hospital</strong> admission <strong>and</strong> the current policy of Do Not Attempt Resuscitation (DNAR).<br />

The def<strong>in</strong>ition of <strong>in</strong>-<strong>hospital</strong> arrest is the disruption of heart mechanical activity as confirmed by the<br />

absence of palpable pulse, no response <strong>and</strong> apnea or presence of ante mortem rhonchus. This def<strong>in</strong>ition<br />

separates the heart from respiratory arrest, characterized by apnea with a palpable pulse. Cardiac arrest is<br />

classified as <strong>in</strong>-<strong>hospital</strong> when it happens <strong>in</strong> a <strong>hospital</strong>ized patient who had pulse on admission to the <strong>hospital</strong>.<br />

The reported <strong>in</strong>cidence of <strong>in</strong>-<strong>hospital</strong> arrest ranges between one to five cases per thous<strong>and</strong> admissions.<br />

Prelim<strong>in</strong>ary data from the UK National Cardiac Arrest Audit (NCAA) suggest that the survival <strong>and</strong> <strong>hospital</strong><br />

discharge after <strong>in</strong>-<strong>hospital</strong> arrest is 13.5% (all cardiac rates). The <strong>in</strong>itial rhythm is VF or pulseless ventricular<br />

tachycardia <strong>in</strong> 18% <strong>and</strong> 44% of them survive <strong>and</strong> exit from the <strong>hospital</strong>. After pulseless electrical activity<br />

(PEA) or asystole only 7% are survived.<br />

Similar data from the National Registry of Cardiopulmonary Resuscitation (NRCPR) of the United<br />

States reported 14,720 arrests <strong>in</strong> 287 U.S.A. <strong>hospital</strong>s. Accord<strong>in</strong>g to these data, 25 to 67% successfully<br />

resuscitated patients (rega<strong>in</strong>ed spontaneous circulation) died the first 24 hours after resuscitation. Most<br />

studies report that 20% of the patients survived <strong>and</strong> exit from the <strong>hospital</strong> <strong>and</strong> a year after the arrest, a rate<br />

between 53% <strong>and</strong> 86% of patients were still alive. While another study reported that 53% of patients who<br />

survived the arrest <strong>and</strong> left the <strong>hospital</strong> were alive five years later. 1<br />

The <strong>in</strong>-<strong>hospital</strong> arrest is often the last event of patient’s progressive deterioration that may have<br />

pathological vital signs for hours or days before the arrest. These precursor elements are recorded but<br />

appropriate actions which could possibly prevent the arrest aren’t implemented timely. 2<br />

Moreover, for every m<strong>in</strong>ute that passes without apply<strong>in</strong>g CPR, the survival of patients with ventricular<br />

fibrillation (AF) is reduced by 7-10% . 3 If the CPR applied immediately, the decrease of survival rate ranges<br />

between 3-4%. 3,4,5 Generally, the immediate implementation of CPR can double the survival of cardiac arrest<br />

victims. 3,4,6<br />

Accord<strong>in</strong>g to the above data there is an urgent need for Resuscitation Team operat<strong>in</strong>g <strong>in</strong> the <strong>hospital</strong>,<br />

which will consist from tra<strong>in</strong>ed <strong>and</strong> qualified staff. This team will be on duty 24 hours a day throughout the<br />

year. 7<br />

5


All the <strong>hospital</strong> staff can call the Resuscitation Team, either through a button visible <strong>and</strong> easily<br />

accessible throughout the <strong>hospital</strong> or through a simple telephone number. These teams <strong>in</strong> the literature are<br />

referred as <strong>Code</strong> <strong>Blue</strong> <strong>Teams</strong> (CBT) or Rapid Response <strong>Teams</strong> (RRT) or Medical Emergency <strong>Teams</strong><br />

(MET). 8<br />

The aim of this essay is to study of the implementation of <strong>Code</strong> blue team to Greek <strong>hospital</strong>s, the evidence<br />

from <strong>hospital</strong>s abroad <strong>and</strong> to document the need for a manual of good practice.<br />

6


CHAPTER 1<br />

CARDIOPULMONARY RESUSCITATION<br />

1.1 General Information – Def<strong>in</strong>itions<br />

Cardiac arrest (CA) is the lead<strong>in</strong>g cause of death worldwide <strong>and</strong> the most frequent cause of death <strong>in</strong><br />

persons over 40 years old. 9 The first heart rate analysis shows ventricular fibrillation (VF) <strong>in</strong> approximately<br />

40% of victims. 10-13 It is likely that more victims have VF or ventricular tachycardia (VT) at the time of<br />

14, 15<br />

collapse, which has turned <strong>in</strong>to asystole by the time first ECG rhythm was recorded.<br />

The guidel<strong>in</strong>es for the treatment of VF have been developed by <strong>in</strong>ternational organizations with aim to<br />

optimize the outcomes. These guidel<strong>in</strong>es are reviewed every five years through review<strong>in</strong>g of publications<br />

with keywords “Arrest – Resuscitation”. 16, 17 Ma<strong>in</strong> objective of these guidel<strong>in</strong>es are the survival of CA<br />

victims.<br />

The steps which should be followed dur<strong>in</strong>g the CPR are described at the cha<strong>in</strong> of survival (Figure 1).<br />

This cha<strong>in</strong> had been proposed 40 years ago by F. Ahnefeld <strong>and</strong> s<strong>in</strong>ce then it has been established as the<br />

symbol for sett<strong>in</strong>g the priority sequence of actions for CPR. The cha<strong>in</strong> is composed of 4 r<strong>in</strong>gs <strong>and</strong> the<br />

important element of each r<strong>in</strong>g is the word “early”. The first r<strong>in</strong>g describes the early recognition <strong>and</strong> early<br />

call for specialized help to prevent the cardiac arrest, the second r<strong>in</strong>g represents the early CPR to buy time,<br />

the third r<strong>in</strong>g shows the early defibrillation to restart the heart <strong>and</strong> the fourth r<strong>in</strong>g symbolizes the early<br />

specialized <strong>hospital</strong> care to store quality of life. The r<strong>in</strong>gs are correlative <strong>and</strong> equally important, so this<br />

sequence should always be followed. “Cardiac Arrest (CA)” is as the disruption of cardiac <strong>and</strong> respiratory<br />

function, which is not accompanied by symptoms, or accompanied by symptoms less than 1 hour . 18<br />

“Cardiopulmonary resuscitation (CPR)” is the sequence of actions aimed to rebound <strong>in</strong> life the cardiac arrest<br />

victim <strong>and</strong> the gradual recovery of vital functions. The CPR <strong>in</strong>tended to improve the transfer of O2 to tissues,<br />

to determ<strong>in</strong>e the specific causes of CA <strong>and</strong> to ma<strong>in</strong>ta<strong>in</strong> the rescued functions. 19<br />

1.2 Epidemiology of CA<br />

The <strong>in</strong>cidence of CA is calculated with difficulty. In Europe, each year the victims of CA are<br />

approximately 700.000. 20 the prevalence of coronary heart disease varies <strong>in</strong> different countries. Although <strong>in</strong><br />

Greece there are no sufficient epidemiological data, the victims of CA are estimated from 5000 to 6000 per<br />

year. The large number of CA victims <strong>in</strong>cludes patients with coronary disease as first symptom <strong>and</strong> patients<br />

who belong to high risk groups <strong>and</strong> the likelihood of hav<strong>in</strong>g CA can be predicted more accurately.<br />

21, 22<br />

7


1.3 Predispos<strong>in</strong>g Factors CA*<br />

Practically, any heart pathology can lead to a variety of fatal arrhythmias with consequence the CA.<br />

Multivariate analysis of selected risk factors (age, systolic blood pressure, heart rate, smok<strong>in</strong>g, diabetes<br />

mellitus, hyperlipidemia) has shown that about half of the CA victims have at least one of these factors.<br />

The overall risk for CA is not simply the numerical sum of the above risk factors. Another important factor<br />

that is associated <strong>and</strong> affected the rate of sudden heart events, ma<strong>in</strong>ly <strong>in</strong> Greece, is obesity. 24<br />

Epidemiological observations <strong>in</strong> the past have shown a correlation between low physical activity <strong>and</strong><br />

risk for sudden death. Moreover, obesity is the cause of many aggravat<strong>in</strong>g factors such as<br />

hypercholesterolemia <strong>and</strong> hyperlipidemia, diabetes mellitus. F<strong>in</strong>ally, obesity contributes as an <strong>in</strong>dependent<br />

factor to the risk of atherosclerosis.<br />

25, 26<br />

Nowadays, CA is a common event, so CPR should be developed <strong>and</strong> cont<strong>in</strong>ually redesigned <strong>in</strong> order to<br />

rescue more <strong>and</strong> more CA victims. The guidel<strong>in</strong>es should be consistent with updated scientific data. The<br />

<strong>in</strong>structions should be as simple as possible <strong>and</strong> easy to learn for implementation by unqualified staff.<br />

20, 23<br />

27, 28, 29<br />

8


CHAPTER 2<br />

FUCTIONAL PRINCIPLES AND OBJECTIVES OF THE CODE BLUE TEAM (CBT) IN<br />

HOSPITAL<br />

The need for a CBT <strong>in</strong> the <strong>hospital</strong> is recognized <strong>in</strong> recent years more <strong>and</strong> more because the team<br />

addresses to life - threaten<strong>in</strong>g situations of <strong>hospital</strong>ized patients <strong>and</strong> provides specialized CPR as <strong>in</strong>dicated.<br />

In <strong>hospital</strong>s with organized CBT, there is a reduction <strong>in</strong> the frequency of <strong>in</strong>-<strong>hospital</strong> arrest. Also, the early<br />

30, 31, 32<br />

CPR by the specialized team <strong>in</strong>creases survival <strong>and</strong> improves the prognosis of CA victims.<br />

The aims of this group are:<br />

� Early recognition of respiratory, cardiac <strong>and</strong> neurological deterioration of the patient, accord<strong>in</strong>g<br />

to the ABCDE approach as def<strong>in</strong>ed by the guidel<strong>in</strong>es of <strong>in</strong>ternational organizations, American<br />

Heart Association (AHA) <strong>and</strong> European Resuscitation Council (ERC), to reduce the number of<br />

cardiac arrests.<br />

� Early <strong>in</strong>itiation of CPR <strong>in</strong> case of CA.<br />

� Early defibrillation if <strong>in</strong>dicated.<br />

� Early care after successful CPR.<br />

2.1 Activation <strong>and</strong> Call<strong>in</strong>g Criteria of CBT<br />

The <strong>hospital</strong> has to establish objective, reproducible <strong>and</strong> easily measurable criteria for the activation of<br />

CBT. The existence of these predef<strong>in</strong>ed criteria <strong>in</strong>creases the reliability of team calls <strong>and</strong> prevents delays.<br />

The criteria are rout<strong>in</strong>e vital signs recorded by the staff <strong>in</strong> an objective, non-<strong>in</strong>vasive manner. When any<br />

member of the staff, medical or nurs<strong>in</strong>g, recognizes one or more criteria <strong>in</strong> a patient which suggests acute<br />

deterioration of his condition, he/she is obliged to call directly the CBT. These criteria are described at the<br />

table below.<br />

9


Table 1. Medical Emergency Team Call<strong>in</strong>g Criteria 33<br />

The call of a specialized team is made through a simple telephone number, usually consist<strong>in</strong>g of 3-4 digits<br />

equal to easily memorized by all personnel. It is also clearly visible <strong>in</strong> apparent po<strong>in</strong>ts throughout the<br />

<strong>hospital</strong>. 33<br />

In the case of CBT call, the follow<strong>in</strong>g should be referred:<br />

� Brief <strong>and</strong> accurate description of the emergency situation, whether it is cardiac arrest or another<br />

type of emergency<br />

� Exact location (floor, cl<strong>in</strong>ic, ward)<br />

� Attend<strong>in</strong>g Physician<br />

10


2.2 Structure <strong>and</strong> roles of CBT<br />

The exact composition of the team (CBT) varies <strong>and</strong> depends on the needs of each <strong>hospital</strong>. Usually,<br />

<strong>in</strong>cludes a doctor <strong>and</strong> a nurse specialized <strong>in</strong> <strong>in</strong>tensive care, the attend<strong>in</strong>g doctor <strong>and</strong> the ward nurse. 2<br />

Both the doctor <strong>and</strong> the nurse, who are specialized <strong>in</strong> <strong>in</strong>tensive care, have knowledge <strong>and</strong> skills for<br />

airway management. The management <strong>in</strong>cludes ma<strong>in</strong>ta<strong>in</strong><strong>in</strong>g a patent airway, suction<strong>in</strong>g, use of appropriate<br />

aids, adequate <strong>and</strong> effective ventilation, advanced airway placement with <strong>in</strong>tubation or other <strong>in</strong>vasive means.<br />

They can practice the algorithms BLS, ALS, ACLS, ATLS (Appendix) which apply to specific CPR, deal<br />

with life-threaten<strong>in</strong>g tachyarrhythmias or bradyarrhythmias, trauma, burn, obstetric emergency, poison<strong>in</strong>g<br />

etc.<br />

In case of CPR, either the specialized doctor or the nurse take the lead<strong>in</strong>g role, specifies the exact role<br />

<strong>and</strong> responsibilities of other team members <strong>and</strong> facilitates the communication between them <strong>in</strong> order to<br />

achieve appropriate function<strong>in</strong>g <strong>and</strong> effectiveness.<br />

Dur<strong>in</strong>g CPR, the assigned roles to the team members are:<br />

� airway management <strong>and</strong> ventilation of the patient (one member)<br />

� perform<strong>in</strong>g effective chest compressions (two members alternative every two m<strong>in</strong>utes)<br />

� provid<strong>in</strong>g safe defibrillation if it is <strong>in</strong>dicated <strong>and</strong> ensur<strong>in</strong>g <strong>in</strong>travascular route <strong>and</strong> the<br />

preparation <strong>and</strong> adm<strong>in</strong>istration of drugs (one member)<br />

� clear <strong>and</strong> concise documentation of code events (one member)<br />

When the CPR is completed successfully, the team is responsible for the safe transportation of the patient <strong>in</strong><br />

the <strong>in</strong>tensive care unit. Instead, if the patient died, the team leader should be responsible for family<br />

<strong>in</strong>formation. 34<br />

2.3 Assessment of the CPR from the team<br />

After complet<strong>in</strong>g each resuscitation effort, the members of the team should meet <strong>in</strong> order to evaluate<br />

what could be improved <strong>in</strong> patient’s care. The process of evaluation by the team provides feedback to<br />

members <strong>and</strong> the capability to address with weaknesses or mistakes. Moreover, through review<strong>in</strong>g their<br />

actions, the novice members of the team are tra<strong>in</strong>ed.<br />

35, 36<br />

11


2.4 Data Documentation - Record Keep<strong>in</strong>g<br />

It is essential for the team to keep a detailed record of all actions taken dur<strong>in</strong>g an emergency response or<br />

CPR. The data archiv<strong>in</strong>g has control, research, education <strong>and</strong> legal purposes. Most <strong>hospital</strong>s have a<br />

prepr<strong>in</strong>ted form (Figures 2-3) for record<strong>in</strong>g the data of <strong>in</strong>-<strong>hospital</strong> resuscitation.<br />

This form is necessary <strong>in</strong> order to achieve uniformity of records <strong>and</strong> to facilitate communication<br />

between departments <strong>in</strong> terms of patient care. In this form, data of the <strong>hospital</strong>, the patient, the circumstances<br />

of the arrest or emergency, therapeutic <strong>in</strong>terventions <strong>and</strong> outcome are recorded. The head nurse of the<br />

department is responsible for the proper completion of the form. This form is duplicated, the orig<strong>in</strong>al is kept<br />

<strong>in</strong> the patient file <strong>and</strong> a copy is filed <strong>and</strong> sent to the Quality Assurance Office of the <strong>hospital</strong>. 37<br />

12


CHAPTER 3<br />

STAFF TRAINING FOR IMMEDIATE CALL OF CBT<br />

3.1 Tra<strong>in</strong><strong>in</strong>g on CCA <strong>and</strong> affect<strong>in</strong>g factors<br />

Tra<strong>in</strong><strong>in</strong>g <strong>in</strong> CPR is urgent need, because the Greek Health System requires specialized resuscitators.<br />

The effective teach<strong>in</strong>g <strong>in</strong> c<strong>and</strong>idate resuscitators will ensure the quality of the given CPR to victims of<br />

cardiac arrest. Therefore, it is important to f<strong>in</strong>d new ways of tra<strong>in</strong><strong>in</strong>g which will familiarize tra<strong>in</strong>ees with the<br />

CPR <strong>and</strong> ma<strong>in</strong>ta<strong>in</strong> knowledge <strong>and</strong> skills dur<strong>in</strong>g time.<br />

The National Cardiopulmonary Resuscitation (EEKAN) of the Central Council of Health (ΚΕΣΥ) of<br />

M<strong>in</strong>istry of Health <strong>and</strong> Social Welfare made compulsory the tra<strong>in</strong><strong>in</strong>g of all health personnel <strong>in</strong> Greece (ΦΕΚ<br />

219/τ.B/22-02-2007).<br />

The CPR boards of many countries have adopted or have developed tra<strong>in</strong><strong>in</strong>g courses for citizens <strong>and</strong><br />

health professionals <strong>in</strong> the native language of tra<strong>in</strong>ees. It is should be mentioned that <strong>in</strong> the U.S., UK <strong>and</strong><br />

other countries, the attendance of these sem<strong>in</strong>ars is essential for health professionals <strong>in</strong> order to be employed<br />

<strong>in</strong> a <strong>hospital</strong>. 38<br />

A small number of tra<strong>in</strong>ees (4-6 persons) should attend this k<strong>in</strong>d of sem<strong>in</strong>ars. The tra<strong>in</strong>ers use<br />

<strong>in</strong>teractive discussions, skill exercises <strong>and</strong> solv<strong>in</strong>g cl<strong>in</strong>ical problems <strong>in</strong> different scenarios. The tra<strong>in</strong>ees are<br />

divided <strong>in</strong> groups with hierarchical distribution <strong>and</strong> leader presence 39 <strong>and</strong> the tra<strong>in</strong>er to tra<strong>in</strong>ee ratio should<br />

range from 1:3 to 1:6. The aim of the sem<strong>in</strong>ars is to improve the skills of the tra<strong>in</strong>ee for treat<strong>in</strong>g with<br />

seriously ill patients. Sophisticated models, simulators <strong>and</strong> virtual reality techniques are now <strong>in</strong>cluded <strong>in</strong><br />

educational diadikasia. 40<br />

There are several factors affect<strong>in</strong>g the tra<strong>in</strong><strong>in</strong>g <strong>in</strong> CPR.<br />

The group of tra<strong>in</strong>ees is mixed <strong>in</strong> age <strong>and</strong> educational status 41 that’s why the sem<strong>in</strong>ars are different<br />

accord<strong>in</strong>g to the group of tra<strong>in</strong>ees. The sem<strong>in</strong>ars BLS, ACLS, ALS, <strong>and</strong> ATLS address at citizens <strong>and</strong><br />

professionals such as GPs, dentists, medical <strong>and</strong> nurs<strong>in</strong>g students, paramedics, rescuers <strong>and</strong> those who work<br />

<strong>in</strong> specific population groups.<br />

The tra<strong>in</strong>ers are chosen accord<strong>in</strong>g to their performance as students <strong>in</strong> CPR sem<strong>in</strong>ars, their theoretical<br />

tra<strong>in</strong><strong>in</strong>g, <strong>and</strong> their ability as leader, their educational skills <strong>and</strong> their motivation. The tra<strong>in</strong>ers should<br />

encourage the tra<strong>in</strong>ees with positive feedback <strong>and</strong> re<strong>in</strong>forcement of their skills. 42<br />

The educational material should be characterized by clarity <strong>and</strong> completeness <strong>and</strong> the tra<strong>in</strong>ees should be<br />

able to underst<strong>and</strong> it. It should be based on the latest guidel<strong>in</strong>es, formulated <strong>in</strong> algorithms <strong>in</strong> order to<br />

facilitate learn<strong>in</strong>g. 43<br />

The importance of tra<strong>in</strong><strong>in</strong>g <strong>in</strong> CPR has been recognized <strong>and</strong> many efforts have been made to improve<br />

the tra<strong>in</strong><strong>in</strong>g conditions <strong>and</strong> the overall educational process. Although there aren’t enough evidence that<br />

13


tra<strong>in</strong><strong>in</strong>g <strong>in</strong> CPR improves survival <strong>and</strong> discharge rates for victims of cardiac arrest, 44,45 it is required for<br />

43, 46<br />

skills acquisition <strong>and</strong> retention dur<strong>in</strong>g time <strong>and</strong> the better care of patients.<br />

F<strong>in</strong>d<strong>in</strong>gs from a recent r<strong>and</strong>omized prospective study demonstrated that students participat<strong>in</strong>g <strong>in</strong> a 2-<br />

hour sem<strong>in</strong>ar for Basic CSD (CSD-B) <strong>and</strong> Automated External defibrillator (AEA) can acquire <strong>and</strong> ma<strong>in</strong>ta<strong>in</strong><br />

skills over an extended period of time. The overall results were comparable with studies based on courses<br />

last<strong>in</strong>g 4 <strong>and</strong> 7 hours. 47<br />

Other studies have shown that nurses are more effective than doctors <strong>in</strong> teach<strong>in</strong>g CPR to other nurses.<br />

This excellence is achieved not only by establish<strong>in</strong>g a complete theoretical background to the students but<br />

also by dissem<strong>in</strong>at<strong>in</strong>g the necessary skills for a dynamic, effective <strong>and</strong> efficient CPR implementation. 42<br />

3.2 Aggravat<strong>in</strong>g <strong>and</strong> Support<strong>in</strong>g Factors for early call of CBT<br />

Accord<strong>in</strong>g to <strong>in</strong>ternational literature, f<strong>in</strong>d<strong>in</strong>gs demonstrated that despite the existence of a resuscitation<br />

team <strong>in</strong> some <strong>hospital</strong>s, the team wasn’t called timely <strong>in</strong> critically ill patients. 48 This delay could have<br />

adverse effects on the patient such as cardiac arrest, multi-organ failure, even death. The f<strong>in</strong>al outcome for<br />

these patients often depends on the ability of medical <strong>and</strong> nurs<strong>in</strong>g staff to recognize early signs of cl<strong>in</strong>ical<br />

deterioration of patients <strong>and</strong> to call the CBT. 49<br />

The key factor, which is responsible for this delay, is the <strong>in</strong>adequate staff tra<strong>in</strong><strong>in</strong>g. The lack of<br />

knowledge may concern to the role of resuscitation team <strong>and</strong> the criteria of the call<strong>in</strong>g. Specifically, research<br />

f<strong>in</strong>d<strong>in</strong>gs had shown that staff often is not familiar with the functional pr<strong>in</strong>ciples, the role of the team <strong>and</strong> the<br />

effectiveness of the team. 50<br />

Other studies had demonstrated that nurs<strong>in</strong>g staff don’t call proper CBT appropriately, due to ignorance<br />

of CBT activation criteria <strong>and</strong> lack of experience <strong>in</strong> deal<strong>in</strong>g with emergency events (i.e. not familiar with the<br />

equipment, do not recognize the extreme abnormal vital signs, etc.) .51 The more theoretical tra<strong>in</strong><strong>in</strong>g <strong>and</strong><br />

cl<strong>in</strong>ical experience has a nurse, the more confident he/she feels for the decision to call the resuscitation team<br />

52, 53<br />

for critically ill patient.<br />

One of the major factors, which promote the appropriate call<strong>in</strong>g of CBT, is the smooth cooperation<br />

among nurses <strong>and</strong> medical staff. On the other h<strong>and</strong>, aggravat<strong>in</strong>g factors for early call of CBT are <strong>in</strong>adequacy<br />

feel<strong>in</strong>gs for patient care <strong>and</strong> the belief of hierarchy elim<strong>in</strong>ation, when the CBT is responsible of the patient<br />

care. 54 F<strong>in</strong>ally, the workload of nurs<strong>in</strong>g staff is a controversial factor, which may support or suspend the early<br />

call of CBT. The cont<strong>in</strong>u<strong>in</strong>g tra<strong>in</strong><strong>in</strong>g of the staff <strong>in</strong> regular manner could prevent the delay <strong>in</strong> call<strong>in</strong>g CBT. 34,<br />

55<br />

14


CHAPTER 4<br />

LITERATURE REVIEW FOR CBT IN HOSPITALS<br />

The objective of CPR is the survival of the patient <strong>and</strong> the assurance of high quality of life. In the<br />

<strong>in</strong>ternational literature, studies demonstrated that the development of CBT leads to a decrease <strong>in</strong> the number<br />

of cardiac arrests <strong>and</strong> the mortality <strong>in</strong> <strong>hospital</strong>. 56<br />

4.1 International Data<br />

In a prospective study conducted <strong>in</strong> Carol<strong>in</strong>ska University <strong>hospital</strong> (Stockholm, Sweden), <strong>in</strong> <strong>hospital</strong><br />

mortality decreased by 10% after the development of CBT. Mortality was reduced by 12% <strong>in</strong> patients<br />

<strong>hospital</strong>ized <strong>in</strong> a medical cl<strong>in</strong>ic <strong>and</strong> 28% <strong>in</strong> patients <strong>hospital</strong>ized before an operation <strong>in</strong> a surgical cl<strong>in</strong>ic. The<br />

number of arrests decreased from 1.12 to 0.83 per 1000 admissions. The call<strong>in</strong>g frequency of CBT was 9.3<br />

per 1000 admissions. 57<br />

A similar study was conducted <strong>in</strong> the U.S. <strong>and</strong> demonstrated that the call of the CBT <strong>in</strong>creased from<br />

13.7 to 25.8 per 1000 admissions after the <strong>in</strong>troduction of objective call<strong>in</strong>g criteria. At the same time, the<br />

<strong>in</strong>cidence of cardiac arrests decreased 17%, from 6.5 to 5.4 per 1000 admissions. Cardiac arrests, deaths <strong>and</strong><br />

unplanned ICU admission decreased due to the development of CBT, as it is supported by numerous other<br />

studies.<br />

In 2000 a CBT was developed at Keck / USC School of Medic<strong>in</strong>e (Los Angeles, California). The<br />

f<strong>in</strong>d<strong>in</strong>gs of the study were similar with the above. An <strong>in</strong>crease of survival after a CA was noticed regardless<br />

of the <strong>in</strong>itial cardiac rate of arrest. The f<strong>in</strong>d<strong>in</strong>gs of the study showed 58% survival rate after CA however the<br />

average for the country was 44%. Particularly, the survival after asystole reaches 48% compared with<br />

country average 35%. 58<br />

A survey conducted also <strong>in</strong> the U.S.A. <strong>and</strong> evaluated data from 507 <strong>hospital</strong>s from January 2000 until<br />

February 2007. They studied 58,543 CA <strong>in</strong> relation with successful CPR, 24-hour survival, <strong>hospital</strong><br />

discharge <strong>and</strong> neurological picture of all the CA victims. Then these data were correlated with the day <strong>and</strong><br />

time arrest was happened (with<strong>in</strong> the week or weekend <strong>and</strong> hour of the day). The study f<strong>in</strong>d<strong>in</strong>gs showed that<br />

survival rates 24 hours after CPR (28.9% vs. 35.4%), until the <strong>hospital</strong> discharge (14.7% vs. 19.8%) <strong>and</strong> the<br />

better neurologic function (11% versus 15.2%) were significantly lower dur<strong>in</strong>g the night than morn<strong>in</strong>g -<br />

afternoon. Also among the CA that occurred dur<strong>in</strong>g morn<strong>in</strong>g-afternoon, the survival was higher on weekdays<br />

than on weekends (20.6% vs. 17.4%) however the night survival was similar between weekdays <strong>and</strong><br />

weekends (14.6% <strong>and</strong> 14.8%). 59 The conclusion of the study was that CBT should be adequately staffed 24<br />

hours every day of the year.<br />

15


In St Cloud Hospital (M<strong>in</strong>nesota) <strong>and</strong> St Dom<strong>in</strong>ic Hospital (Mississippi) the survival of CA victims was<br />

studied before <strong>and</strong> after the tra<strong>in</strong><strong>in</strong>g of their staff <strong>in</strong> CPR accord<strong>in</strong>g to AHA guidel<strong>in</strong>es. The survival was<br />

<strong>in</strong>creased by 60% from 17.5% to 28%. 60 This study demonstrated that the CPR should be done by<br />

appropriately qualified staffed, tra<strong>in</strong>ed through CPR guidel<strong>in</strong>es from <strong>in</strong>ternational organizations.<br />

At the Aust<strong>in</strong> Hospital (Melbourne, Australia), the <strong>in</strong>cidence of <strong>in</strong>-<strong>hospital</strong> arrests was studied before<br />

<strong>and</strong> after the establishment of criteria for early call<strong>in</strong>g of CBT. The f<strong>in</strong>d<strong>in</strong>gs demonstrated a gradual decl<strong>in</strong>e<br />

dur<strong>in</strong>g the 4 years of study. Before the implementation of specific criteria there were 4,06 arrests per 1000<br />

admissions, 2,45 dur<strong>in</strong>g the <strong>in</strong>troductory tra<strong>in</strong><strong>in</strong>g <strong>and</strong> awareness of staff with the criteria of early call CBT<br />

<strong>and</strong> 1,90 after the complete implementation of the criteria. It is noteworthy that 17 calls to CBT correspond<br />

to the avoidance of one CA. 61<br />

In a recently published study (March-April 2012) qualitative <strong>and</strong> quantitative measures of resuscitation<br />

team were evaluated <strong>in</strong> a California <strong>hospital</strong> for five years period (2005-2010). The team was consisted from<br />

specialized nurses, responsible for assess<strong>in</strong>g <strong>and</strong> monitor<strong>in</strong>g the critically ill patients <strong>in</strong> the <strong>hospital</strong>. The<br />

team purpose is to recognize early signs of deterioration to prevent CA <strong>in</strong> direct cooperation with the rest of<br />

the nurs<strong>in</strong>g <strong>and</strong> medical staff. The follow<strong>in</strong>g diagrams showed all the statistics related to the study. 62<br />

Figure 1: Frequency of calls at CBT<br />

16


Figure 2: Indicators of mortality before <strong>and</strong> after the <strong>in</strong>troduction of CBT<br />

Figure 3: Frequency of CPR <strong>in</strong> all calls of CBT<br />

17


Figure 4: Survival rates after early <strong>in</strong>tervention of CBT<br />

Figure 5: Percentages of survival until <strong>hospital</strong> discharge after CA<br />

Calzavacca et al studied the features of patients for whom the CBT was called. They found that 22.5%<br />

of the patients were evaluated by the team more than once. These patients were <strong>hospital</strong>ized <strong>in</strong> surgical<br />

wards, stayed longer at the <strong>hospital</strong> by 50% <strong>and</strong> <strong>in</strong>creased mortality by 34,6%, compared to patients who<br />

need one evaluation by the CBT. 63<br />

18


F<strong>in</strong>ally, another survey was conducted by the Ottawa Hospital (Canada) <strong>and</strong> showed that 27% of<br />

patients, for whom the CBT were called, needed constantly ICU admission. Also, they found that the first 2<br />

years of implementation of CBT the rate decreased from 2, 53 CA patients to 1, 3 per 1000 admissions. 64<br />

Although, the <strong>in</strong>ternational literature is full of studies about the value of a resuscitation team, there is a<br />

need for more <strong>in</strong>vestigation concern<strong>in</strong>g patient outcomes. Moreover, the effectiveness of a CBT requires<br />

constant tra<strong>in</strong><strong>in</strong>g, permanent record<strong>in</strong>g of <strong>in</strong>terventions <strong>and</strong> feedback to improve quality of given care.<br />

A common basis for evaluat<strong>in</strong>g the data from CPR was published after a session <strong>in</strong> 2006 with<br />

International Liaison Committee on Resuscitation (AHA, ARC, ERC, HSFC, IHF, RCSA, <strong>and</strong> NZRC), the<br />

American Heart Association Emergency, Cardiovascular Care Committee, Council on Cardiopulmonary,<br />

Perioperative, <strong>and</strong> Critical Care <strong>and</strong> Interdiscipl<strong>in</strong>ary Work<strong>in</strong>g Group on Quality of Care <strong>and</strong> Outcomes<br />

Research. The produced guidel<strong>in</strong>es concerned the collection <strong>and</strong> record<strong>in</strong>g of data <strong>and</strong> studies <strong>in</strong> relation to<br />

resuscitation teams. 37 By us<strong>in</strong>g a specific form (Figure 4), it is easier to record the frequency, type <strong>and</strong><br />

outcome of <strong>hospital</strong> events.<br />

The process<strong>in</strong>g of data ensures better plann<strong>in</strong>g of the <strong>in</strong>tervention system. At the same time, data can be used<br />

to develop guidel<strong>in</strong>es for better treatment of <strong>hospital</strong>ized patients <strong>and</strong> prevention of medical errors.<br />

4.2 National Data<br />

Accord<strong>in</strong>g to the literature, there are no published data concern<strong>in</strong>g the development <strong>and</strong> function of<br />

resuscitation teams <strong>in</strong> Greek <strong>hospital</strong>s. In public <strong>hospital</strong>s, there is no evidence for existence CBT. Cardiac<br />

arrest <strong>and</strong> threaten-life emergencies treated by ICU doctors, anesthesiologists, cardiologists, who are try<strong>in</strong>g<br />

to coord<strong>in</strong>ate the CPR. Therefore, several times difficulties were presented dur<strong>in</strong>g the CPR process such as<br />

there is no specialized staff, there is no staff available to the ward, they aren’t aware of the emergency<br />

equipment etc. The result of the above difficulties is the valuable time loss; there is no coord<strong>in</strong>ation at<br />

<strong>in</strong>terventions with adverse consequences <strong>in</strong> care of the patient. Moreover, no record of the arrests was kept<br />

<strong>and</strong> the needs <strong>and</strong> problems aris<strong>in</strong>g are not documented, so the need for develop<strong>in</strong>g CBT is not recognized.<br />

Exceptions are some private <strong>hospital</strong>s which have adopted the function of such teams operat<strong>in</strong>g <strong>in</strong><br />

accordance with <strong>in</strong>ternational guidel<strong>in</strong>es. There is an easy telephone number for call<strong>in</strong>g the team. The team<br />

composition is fixed for all the hours <strong>and</strong> days of a year. The team is coord<strong>in</strong>ated <strong>and</strong> the role of each<br />

member is dist<strong>in</strong>ct. At the end of each <strong>in</strong>tervention the data are collected <strong>and</strong> documented at a predeterm<strong>in</strong>ed<br />

form (Figure 5) which is sent to the quality assurance office.<br />

19


CONCLUSIONS<br />

The number of CA victims out-<strong>hospital</strong> <strong>and</strong> <strong>in</strong>-<strong>hospital</strong> is very large, <strong>in</strong> Europe <strong>and</strong> worldwide. CA is<br />

the lead<strong>in</strong>g cause of death worldwide <strong>and</strong> the most frequent cause of death <strong>in</strong> people over 40 years old. The<br />

early CPR by qualified personnel <strong>in</strong>creases the survival <strong>and</strong> improves the f<strong>in</strong>al neurological outcome<br />

contribut<strong>in</strong>g to a better quality of life.<br />

Accord<strong>in</strong>g to the literature, <strong>hospital</strong>s with CBT have significantly reduced the number of CA victims<br />

<strong>and</strong> CA mortality. In these <strong>hospital</strong>s there is complete record<strong>in</strong>g of the frequency, nature <strong>and</strong> outcome of<br />

events they faced. The process<strong>in</strong>g of these data ensures better plann<strong>in</strong>g of the <strong>in</strong>tervention system. Also, data<br />

can be used to develop guidel<strong>in</strong>es for better care of <strong>hospital</strong>ized patients <strong>and</strong> prevention of medical errors.<br />

Therefore, the need for the development of CBT <strong>in</strong> Greek <strong>hospital</strong> is urgent. This team should consist<br />

from tra<strong>in</strong>ed <strong>and</strong> qualified staff. This team will be on call 24 hours a day throughout the year. The CBT is<br />

called for the early care of CA victims <strong>and</strong> other life -threaten<strong>in</strong>g situations accord<strong>in</strong>g to <strong>in</strong>ternational<br />

guidel<strong>in</strong>es.<br />

The obligatory tra<strong>in</strong><strong>in</strong>g of all health professionals <strong>in</strong> CPR will ensure the achievement of successful<br />

CBT function. The tra<strong>in</strong><strong>in</strong>g programs should follow guidel<strong>in</strong>es <strong>and</strong> be developed by <strong>in</strong>ternational<br />

organizations. The tra<strong>in</strong><strong>in</strong>g should be cont<strong>in</strong>uous <strong>in</strong> order to guarantee the ma<strong>in</strong>tenance of theoretical<br />

knowledge <strong>and</strong> practical skills dur<strong>in</strong>g time. Moreover, <strong>in</strong> many countries the attendance of CPR sem<strong>in</strong>ars is<br />

necessary to health professionals for be<strong>in</strong>g employed <strong>in</strong> the <strong>hospital</strong>.<br />

20


Figure 1.<br />

APPENDIX<br />

21


Figure 2<br />

22


Figure 3.<br />

23


Figure 4.<br />

24


Figure 5<br />

26


ALGORITHMS OF IN-HOSPITAL CARDIAC ARREST<br />

27


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