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Belgian Week of Gastroenterology

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<strong>Belgian</strong> <strong>Week</strong> <strong>of</strong><br />

<strong>Gastroenterology</strong><br />

ANTWERP Hilton, March 4 - 6, 2010<br />

www.belgianweek.be or www.bwge.be<br />

Thursday 4 FrIday 5 saTurday 6


Thursday 4<br />

FrIday 5<br />

saTurday 6<br />

WElcomE aDDrEss<br />

dear colleagues,<br />

i would like to invite you at our 22nd <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology taking<br />

place from March 4 to 6, 2010 in the beautiful city <strong>of</strong> antwerp.<br />

last year was a big success and as we do not have many options in Belgium for<br />

good locations for such a congress (599 participants in 2008; 628 in 2009), we<br />

preferred to come back to the hilton hotel in 2010. Perhaps we shall change<br />

the location in 2011.<br />

this year we received 279 abstracts from all the research groups and joint meeting.<br />

it is my pleasure to invite you to the friday night dinner and Party on March 5<br />

at the appelmans Brasserie, nearby the hilton hotel.<br />

on saturday we will have the seven societies symposium organised by the<br />

Vlaamse Vereniging van gastroenterologie with the topic: “over and Under<br />

nutrition”. this year, in parallel with the seven societies symposium, the<br />

Pathology club is organising «the President’s day» for the emeritate <strong>of</strong> Pr<strong>of</strong>.<br />

karel geboes.<br />

antwerp is a fantastic city with lots <strong>of</strong> points <strong>of</strong> interest and nice shopping<br />

facilities. a list <strong>of</strong> suggested social activities is available on our website.<br />

i would like to thank all scientifi c committees and biomedical partners for their<br />

support in organising this <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology 2010.<br />

isabelle colle<br />

scientifi c coordinator<br />

All abstracts <strong>of</strong> lectures will be published in Acta Gastroenterologica Belgica.<br />

Acta Gastroenterologica is accessible on internet :<br />

www.acta-gastroenterologica.be<br />

P. Michielsen, Editor in chief<br />

P. Stärkel, Deputy Editor<br />

2 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


Thursday 4<br />

FrIday 5<br />

saTurday 6<br />

INDEX<br />

WelcoMe address 2<br />

general inforMation 6<br />

steering coMMittee 7<br />

inVited lectUres 8<br />

satellite syMPosia 10<br />

thUrsday March 4 :<br />

Basl / Blic 12<br />

og – fWo 14<br />

<strong>Belgian</strong> Pancreatic clUB 16<br />

sMall BoWel groUP 17<br />

Joint Meeting : session a 18<br />

Joint Meeting : session B 19<br />

iBd 20<br />

<strong>Belgian</strong> hP stUdy groUP 21<br />

Basl Poster session 22<br />

PrograM oVerVieW 24<br />

friday March 5 :<br />

Joint Meeting : session c 26<br />

Joint Meeting : Plenary session d 27<br />

Joint Meeting : Plenary session e 28<br />

Joint Meeting : session f 29<br />

Bgdo / radiology / Pathology 30<br />

4 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


Bsgie / BesPghan 33<br />

nUtrition groUP 34<br />

Poster sessions :<br />

satUrday March 6 :<br />

Joint Meeting 36<br />

Bsgie 37<br />

iBd 37<br />

7 societies syMPosiUM :<br />

« over and under nutrition» 38<br />

gi Pathology clUB :<br />

« the President’s day» 40<br />

friday night Party 43<br />

take Me to hilton antWerP 44<br />

BWg 2010 Partners 48<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

5<br />

Thursday 4 FrIday 5 saTurday 6


Thursday 4<br />

FrIday 5<br />

saTurday 6<br />

gENEral INformatIoN<br />

AccreditAtion<br />

certificates for accreditation will be provided at the end <strong>of</strong> each 1/2 day session (3cP units) to the<br />

registered delegates who have attended the respective sessions. (type-rubriek 3, cP18, organizer<br />

2730, <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology)<br />

LAnguAge<br />

dutch, french and english. english (British spelling) for abstracts, slides and announcements.<br />

AbstrActs<br />

authors were invited to send abstracts through the congress website until november 30th and to choose either the<br />

« Joint Meeting » (clinical and Basic research with clinical impact) or the appropriate research groups.<br />

106 abstracts were submitted to the Joint meeting and in total we received 279 abstracts, research groups included!<br />

the Joint Meeting oral presentations were selected by the Joint Meeting selection committee and will be presented<br />

on thursday afternoon and on friday. the research groups oral presentations were selected by the selection<br />

committee <strong>of</strong> each group.<br />

for the Joint Meeting, the abstracts were scored anonyMoUsly from 0 to 10, on the basis <strong>of</strong> originality and<br />

scientific value by each <strong>of</strong> the members <strong>of</strong> the selection committee. it gathers experts in the different fields <strong>of</strong> gastroenterology.<br />

the abstracts were then separated into several categories, the highest scores being presented during<br />

the Plenary session on friday morning and friday afternoon, in increasing order <strong>of</strong> scores.<br />

Prizes will be awarded on saturday morning for the two best oral presentations at the Joint Meeting in Basic<br />

research and clinical research. the Bgdo will also present an award for the best communication in oncology.<br />

the best iBd abstract will be awarded by both iBd patient associations. on thursday noon, 2 Basl prizes will be<br />

awarded at the end <strong>of</strong> the morning session for the best basic & clinical oral presentation in hepatology.<br />

venue<br />

hilton antwerp hotel – groenplaats – 2000 antwerp<br />

tel: +32 3 204 12 12 / fax: +32 3 204 86 88.<br />

the conference centre has separate elevators to access from the lobby <strong>of</strong> the hotel.<br />

the 3rd floor is the main floor <strong>of</strong> the congress where you will find: the registration, some conference<br />

rooms and the exhibition room.<br />

PArking<br />

here are the closest parkings to the hilton antwerp :<br />

- groenplaats Parking: the hilton antwerp has reserved 200 places for our congress.<br />

- Meir Parking.<br />

- Brabo Parking.<br />

- lombardia Parking.<br />

event coordinAtor<br />

anne-france de Meyer – 102, av. J&P carsoel – 1180 Brussels<br />

tel : +32 2 375 36 26 / fax : +32 2 375 47 84 / e-mail : anne.france.de.meyer@skynet.be<br />

HoteL rooms At tHe HiLton<br />

Please contact anne-france de Meyer.<br />

type room single double<br />

hilton guest 199 € 219 €<br />

deluxe 249 € 259 €<br />

executive 279 € 289 €<br />

AntwerP tourism <strong>of</strong>fice<br />

tourism antwerp – grote Markt, 13 – 2000 antwerp<br />

tel : +32 3 232 01 03 / e-mail : visit@antwerpen.be<br />

6 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


stEErINg commIttEE<br />

Scientific co o r d i n at o r<br />

o f t h e Jo i n t Me e t i n g<br />

isabelle colle<br />

Se v e n SocietieS<br />

g. d’haens, g. Van assche<br />

(VVge, Vlaamse Vereniging voor gastro-enterologie)<br />

J.l. Van laetheM, J.c. deBongnie<br />

(srBge, société royale Beige de gastro-entérologie)<br />

P. dePreZ, P. Van der sPek<br />

(Bsgie, <strong>Belgian</strong> society <strong>of</strong> gastrointestinal endoscopy)<br />

a. de rooVer, J. lerUt,<br />

J. M. collard (UPPer g.i section),<br />

P. Pattyn (colo-rectal section),<br />

r. troisi (hBP section)<br />

(rBss, royal <strong>Belgian</strong> society <strong>of</strong> surgery)<br />

B. oP de Beeck, e. danse<br />

(srBr-kBVr, royal <strong>Belgian</strong> society <strong>of</strong> radiology,<br />

digestive radiology and abdominal imaging)<br />

J. delWaide, h. reynaert<br />

(Basl, <strong>Belgian</strong> association for the study <strong>of</strong> the liver)<br />

J.l. Van laetheM, e. VancUtseM<br />

(Bgdo, <strong>Belgian</strong> group <strong>of</strong> digestive oncology)<br />

re S e a r c h gr o u p S<br />

i. dePoortere, B. de Winter<br />

(og-fWo, gastro-intestinal regulatory mechanisms)<br />

k. geBoes, a. JoUret-MoUrin<br />

(gastro-intestinal Pathology club)<br />

g. VeereMan, i. h<strong>of</strong>fMan<br />

(Be sPghan, <strong>Belgian</strong> society for Paediatric<br />

gastroenterology, hepatology and nutrition)<br />

a. Van gossUM<br />

(sBnc, société Belge de nutrition clinique)<br />

d. yseBaert<br />

(VVkVM, Vlaamse Vereniging voor klinische<br />

Voeding en Metabolisme)<br />

Scientific Se c r e ta r i e S o f t h e<br />

Se v e n SocietieS Sy M p o S i uM<br />

Martin hiele (VVge)<br />

geert d’haens (VVge)<br />

e. loUis, s. VerMeire<br />

(<strong>Belgian</strong> iBd research group)<br />

M. delhaye<br />

(BPc, <strong>Belgian</strong> Pancreatic club)<br />

V. laMy, f. Mana<br />

(BhPsg, <strong>Belgian</strong> helicobacter Pylori study group)<br />

d. UrBain<br />

(<strong>Belgian</strong> small Bowel group)<br />

J. Pirenne, h. Van VlierBerghe<br />

(Blic, <strong>Belgian</strong> liver intestine committee)<br />

P. flaMen, l. carP<br />

(nUclear Medicine)<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

7<br />

Thursday 4 FrIday 5 saTurday 6


Thursday 4<br />

FrIday 5<br />

saTurday 6<br />

INvItED lEcturEs<br />

Thursday 4<br />

Basl / BlIc : room lijn<br />

12h15 : apoptosis, from bench to bedside.<br />

M. BilodeaU / Montreal, canada<br />

og-fWo : room teun<br />

09h00 : Pharmacology <strong>of</strong> inflammatory visceral pain.<br />

P. holZer / austria<br />

11h00 : Pharmacotherapy in somatic pain research.<br />

g. hans / antwerp - Belgium<br />

BElgIaN PaNcrEatIc cluB : room sancy<br />

09h00 : Pathophysiology <strong>of</strong> inflammatory pancreatic<br />

diseases and its clinical implications.<br />

J.l. frossard / geneva, switzerland<br />

11h15 : screening individuals for pancreatic cancer:<br />

for whom? how? when? and how frequently?<br />

P. dePreZ / Brussels<br />

JoINt mEEtINg BElgIaN WEEk : room lijn<br />

15h00 : m. Hautekeete lecture : sepsis and cirrhosis.<br />

J.l. Vincent / (erasme, Brussels)<br />

og-fWo : room teun<br />

14h00 : Development <strong>of</strong> postinflammatory animal<br />

models and visceral hyperalgesia.<br />

n. Vergnolle / france<br />

HP grouP : room tiffany<br />

14h00 : the diagnosis <strong>of</strong> resistance <strong>of</strong> H. pylori by other methods<br />

than culture: what, how, costs and availability.<br />

V.y. MiendJe deyi / Brussels<br />

IBD grouP : room sancy<br />

14h00 : Er stress and autophagy.<br />

a. kaser / austria<br />

15h05 : Impaired autophagy in crohn’s disease:<br />

an opened gate to invasive bacteria?<br />

a. darfeUille - MichaUd / france<br />

16h00 : crohn’s disease: th17 and/or th1 disease?<br />

s. Brand / germany<br />

17h05 : tNfdeltaarE mice: a model to study EIms in cD.<br />

d. eleWaUt / ghent<br />

8 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


FrIday 5<br />

BgDo / raDIology : room sancy<br />

09h30 : radionucleide therapy for primary liver tumors.<br />

B. laMBert / UZ gent<br />

09h50 : sIrt: Nuclear medicine considerations<br />

and pitfalls.<br />

P. flaMen / Bordet, Brussels<br />

10h10 : angiographic considerations in patients<br />

undergoing liver-directed therapies.<br />

g. MaleUX / UZ leuven<br />

12h00 : radionucleide therapy for Neuroendocrine tumors: indications and pitfalls.<br />

c. de roose / UZ leuven<br />

BgDo / PatHology : room sancy<br />

14h00 : Emphasis on the key role <strong>of</strong> the pathologist in kras mutation testing in the selection<br />

<strong>of</strong> patients for Egfr-targeted therapy in colorectal cancer.<br />

a. hoorens / UZ Brussels<br />

16h00 : Diagnostic algorithm <strong>of</strong> lynch syndroom.<br />

h. Vasen / leiden, the netherlands<br />

saTurday 6<br />

sEvEN socIEtIEs symPosIum: ovEr aND uNDEr NutrItIoN<br />

room teun/lijn<br />

see all invited lectures page : 38<br />

gI PatHology cluB: tHE PrEsIDENt’s Day<br />

room sancy/tiffany<br />

see all invited lectures page : 40<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

9<br />

Thursday 4 FrIday 5 saTurday 6


Thursday 4<br />

FrIday 5<br />

saTurday 6<br />

satEllItE symPosIa<br />

Thursday MarCh 4<br />

room teun<br />

13h15-14h00 BayEr<br />

«controversies in the treatment <strong>of</strong> Hepatocellular carcinoma»<br />

speakers : c. Verslype (UZ leuven) / i. Bobarth (Ucl st luc)<br />

room teun<br />

17h30-18h15 MOVETIs<br />

« the clinical dilemma <strong>of</strong> chronic constipation:<br />

prucalopride a new way out?»<br />

speakers: h. Piessevaux (Ucl st luc) / J. tack (kUleuven) / M. Van outryve (UZ antwerpen)<br />

room teun<br />

18h15-19h00 GILEad<br />

« long-term efficacy <strong>of</strong> ten<strong>of</strong>ovir monotherapy for hepatitis B<br />

virus-monoinfected patients after failure <strong>of</strong> nucleoside/nucleotide<br />

analogues.»<br />

speakers: f. van Bömmel (Berlin, germany)<br />

FrIday MarCh 5<br />

room teun / LiJn<br />

13h15-14h00 sOLVay<br />

«Exocriene pancreatic insufficiency: different tests and outcome»<br />

speakers: k. Verbeke (kUleuven) / M. delhaye (UlB erasme)<br />

room teun / LiJn<br />

17h30-18h15 sChErING PLOuGh<br />

«mucosal Healing : the corner stone <strong>of</strong> the IBD battle»<br />

room teun / LiJn<br />

18h15-19h00 MENarINI<br />

oBIs study: use <strong>of</strong> Psychomedicine in case <strong>of</strong> IBs<br />

speaker: B. fischler (UlB saint-Pierre)<br />

use <strong>of</strong> musculotrope spasmolytica: lesson from the oBIs study<br />

speaker: J. tack (kUleuven)<br />

Interest in food guidelines in case <strong>of</strong> IBs<br />

speaker: h. Piessevaux (Ucl st luc)<br />

10 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


One liver. One life. One VIREAD<br />

P.P. 416,75 €<br />

NAME OF THE MEDICINAL PRODUCT Viread 245 mg fi lm-coated tablets QUALITATIVE AND QUANTITATIVE COMPOSITION Each fi lm-coated tablet contains 245 mg <strong>of</strong> ten<strong>of</strong>ovir disoproxil (as fumarate), equivalent to<br />

300 mg <strong>of</strong> <strong>of</strong> ten<strong>of</strong>ovir disoproxil fumarate, or 136 mg <strong>of</strong> ten<strong>of</strong>ovir. Excipient(s): Excipient(s): Each tablet contains 153.33 mg lactose monohydrate. For a full list <strong>of</strong> excipients, see section 6.1.PHARMACEUTICAL FORM Film-coated<br />

tablet. tablet. Light blue, almond-shaped, fi lm-coated tablets, debossed on on one one side with the markings “GILEAD” and and “4331” and and on on the other side with the the marking “300”. CLINICAL PARTICULARS Therapeutic indications<br />

HIV-1 infection: Viread is indicated in combination with other antiretroviral medicinal products for the treatment <strong>of</strong> HIV-1 infected adults over 18 years <strong>of</strong> age. The demonstration <strong>of</strong> benefi t <strong>of</strong> Viread in HIV-1 infection is<br />

based on results results <strong>of</strong> one study study in in treatment-naïve patients, including patients with a high viral load (> (> 100,000 copies/ml) and and studies in which Viread was added to stable background therapy (mainly tritherapy) in<br />

antiretroviral pre-treated patients experiencing early virological failure (< 10,000 copies/ml, with the majority <strong>of</strong> patients having having < < 5,000 copies/ml). The choice <strong>of</strong> Viread Viread to treat antiretroviral experienced patients with with<br />

HIV-1 infection should be based on individual viral resistance testing and/or treatment history <strong>of</strong> patients. Hepatitis B infection: Viread is indicated for the treatment <strong>of</strong> chronic hepatitis B in adults with compensated liver<br />

disease, with evidence <strong>of</strong> active viral replication, persistently elevated serum alanine aminotransferase (ALT) levels and histological evidence <strong>of</strong> active infl ammation and/or fi brosis. This indication is based on histological,<br />

virological, biochemical and serological responses mainly in adult nucleoside-naïve patients with HBeAg positive and HBeAg negative chronic hepatitis B with compensated liver function. Posology and method <strong>of</strong><br />

administration Therapy should be initiated by a physician experienced in the management <strong>of</strong> HIV infection and/or treatment <strong>of</strong> chronic hepatitis B. In exceptional circumstances in patients having particular diffi culty in<br />

swallowing, Viread can be administered following disintegration <strong>of</strong> the tablet in at least 100 ml <strong>of</strong> water, orange juice or grape juice. Adults: The recommended dose for the treatment <strong>of</strong> HIV or for the treatment <strong>of</strong><br />

chronic hepatitis B is 245 mg (one tablet) once daily taken orally with food. Chronic hepatitis B: The optimal duration <strong>of</strong> treatment is unknown. Treatment discontinuation may be considered as follows:- In HBeAg positive<br />

patients without cirrhosis, treatment should be administered for at least 6-12 months after HBe seroconversion (HBeAg loss and HBV DNA loss with anti-HBe detection) is confi rmed or until HBs seroconversion or there<br />

is loss <strong>of</strong> effi cacy (see section 4.4). Serum ALT and HBV DNA levels should be followed regularly after treatment discontinuation to detect any late virological relapse. - In HBeAg negative patients without cirrhosis,<br />

treatment should be be administered at least until HBs HBs seroconversion or there is evidence <strong>of</strong> loss <strong>of</strong> effi cacy. With prolonged treatment for more than 2 years, regular reassessment is recommended recommended to confi rm that<br />

continuing the selected therapy remains appropriate for the patient. Paediatric patients: Viread is not recommended for use in children below the age <strong>of</strong> 18 years due to insuffi cient data on safety and effi cacy<br />

(see section 5.2). Elderly: No data are available on which to make a dose recommendation for patients over the age <strong>of</strong> 65 years (see section 4.4). Renal insuffi ciency:<br />

Ten<strong>of</strong>ovir is eliminated by renal excretion and the<br />

exposure to ten<strong>of</strong>ovir increases in patients with renal dysfunction. There are limited data on the safety and effi cacy <strong>of</strong> ten<strong>of</strong>ovir disoproxil fumarate in patients with moderate and severe renal impairment (creatinine<br />

clearance < 50 ml/min) and long term safety data has not been evaluated for mild renal impairment (creatinine clearance 50-80 ml/min). Therefore, in patients with renal impairment ten<strong>of</strong>ovir disoproxil fumarate should<br />

only be used if the potential benefi ts <strong>of</strong> treatment are considered to outweigh the potential risks. Dose interval adjustments are recommended for patients with creatinine clearance < 50 ml/min. Mild renal impairment<br />

(creatinine clearance 50-80 ml/min): Limited data from clinical studies support once daily dosing <strong>of</strong> ten<strong>of</strong>ovir disoproxil fumarate in patients with mild renal impairment. Moderate renal impairment (creatinine clearance<br />

30-49 ml/min): Administration <strong>of</strong> 245 mg ten<strong>of</strong>ovir disoproxil (as fumarate) every 48 hours is recommended based on modelling <strong>of</strong> single-dose pharmacokinetic data in non-HIV and non-HBV infected subjects with<br />

varying degrees <strong>of</strong> renal impairment, including end-stage renal disease requiring haemodialysis, but has not been confi rmed in clinical studies. Therefore, clinical response to treatment and renal function should be closely<br />

monitored in these patients (see sections 4.4 and 5.2). Severe renal impairment (creatinine clearance < 30 ml/min) and haemodialysis patients: Adequate dose adjustments cannot be applied due to lack <strong>of</strong> alternative tablet<br />

strengths, therefore use in this group <strong>of</strong> patients is not recommended. If no alternative treatment is available, prolonged dose intervals may be used as follows: Severe renal impairment: 245 mg ten<strong>of</strong>ovir disoproxil (as<br />

fumarate) may be administered every 72-96 hours (dosing twice a week). Haemodialysis patients: 245 mg ten<strong>of</strong>ovir disoproxil (as fumarate) may be administered every 7 days following completion <strong>of</strong> a haemodialysis<br />

session*. These dose adjustments have not been confi rmed in clinical studies. Simulations suggest that the prolonged dose interval is not optimal and could result in increased toxicity and possibly inadequate response.<br />

Therefore clinical response to treatment and renal function should be closely monitored (see sections 4.4 and 5.2). * Generally, Generally, once weekly dosing assuming three haemodialysis sessions per week, each <strong>of</strong> approximately<br />

4 hours duration or after 12 hours cumulative haemodialysis. No dosing recommendations can be given for non-haemodialysis patients with creatinine clearance < 10 ml/min. Hepatic impairment:<br />

No dose adjustment<br />

is required in patients with hepatic impairment (see sections 4.4 and 5.2). If Viread is discontinued in patients with chronic hepatitis B with or without HIV co-infection, these patients should be closely monitored for<br />

evidence <strong>of</strong> exacerbation <strong>of</strong> hepatitis (see section 4.4). Contraindications Hypersensitivity to the active substance or to any <strong>of</strong> the excipients. Undesirable effects HIV-1:<br />

Assessment <strong>of</strong> adverse reactions from clinical<br />

study data is based on experience in two studies in 653 treatment-experienced patients receiving treatment with ten<strong>of</strong>ovir disoproxil fumarate (n = 443) or placebo (n = 210) in combination with other antiretroviral<br />

medicinal products for 24 weeks and also in a double-blind comparative controlled study in which 600 treatment-naïve patients received treatment with ten<strong>of</strong>ovir disoproxil 245 mg (as fumarate) (n = 299) or stavudine<br />

(n = 301) in combination with lamivudine and efavirenz for 144 weeks. Approximately one third <strong>of</strong> patients can be expected to experience adverse reactions following treatment with ten<strong>of</strong>ovir disoproxil fumarate in<br />

combination with other antiretroviral agents. These reactions are usually mild to moderate gastrointestinal events. The adverse reactions with suspected (at least possible) relationship to treatment are listed below by<br />

body system organ class and absolute frequency. Within each frequency grouping, undesirable effects are presented in order <strong>of</strong> decreasing seriousness. Frequencies are defi ned as very common ( (≥ 1/10) or common<br />

(≥ 1/100, < 1/10). See also Post-marketing experience below.<br />

Metabolism and nutrition disorders: Very common: hypophosphataemia Nervous system disorders: Very common: dizziness<br />

Gastrointestinal disorders: Very<br />

common: diarrhoea, vomiting, nauseaCommon: fl atulence Approximately 1% <strong>of</strong> ten<strong>of</strong>ovir disoproxil fumarate-treated patients discontinued treatment due to the gastrointestinal events. Combination antiretroviral therapy<br />

has has been been associated with metabolic abnormalities such as as hypertriglyceridaemia, hypertriglyceridaemia, hypercholesterolaemia, insulin resistance, hyperglycaemia hyperglycaemia and hyperlactataemia (see section 4.4). Combination Combination antiretroviral therapy has<br />

been associated with redistribution <strong>of</strong> <strong>of</strong> body fat (lipodystrophy) in in HIV patients patients including the loss <strong>of</strong> peripheral and facial subcutaneous fat, increased intra-abdominal and visceral fat, breast hypertrophy and dorsocervical<br />

dorsocervical<br />

fat accumulation (buffalo hump). In a 144-week controlled clinical study in antiretroviral-naïve patients that compared ten<strong>of</strong>ovir disoproxil fumarate with stavudine in combination with lamivudine and efavirenz, patients<br />

who received ten<strong>of</strong>ovir disoproxil had a signifi cantly lower incidence <strong>of</strong> lipodystrophy compared with patients who received stavudine. The ten<strong>of</strong>ovir disoproxil fumarate arm also had signifi cantly smaller mean increases<br />

in fasting triglycerides and total cholesterol than the comparator arm. In HIV infected patients with severe immune immune defi ciency at at the time <strong>of</strong> initiation <strong>of</strong> combination antiretroviral therapy (CART), an infl infl ammatory reaction<br />

to asymptomatic or residual opportunistic infections may arise (see section 4.4). Cases <strong>of</strong> osteonecrosis have been reported, particularly in patients with generally acknowledged risk factors, advanced HIV disease or<br />

long-term exposure to to combination antiretroviral therapy (CART). The frequency <strong>of</strong> this is is unknown (see section 4.4). Hepatitis B: Assessment <strong>of</strong> adverse reactions from clinical study data is primarily based on experience<br />

in in two double-blind comparative controlled studies (GS-US-174-0102 and GS-US-174-0103) in in which 641 patients patients with chronic hepatitis hepatitis B and compensated liver disease received treatment with ten<strong>of</strong>ovir disoproxil<br />

245 mg (as fumarate) daily (n = 426) or adefovir dipivoxil 10 mg daily (n = 215) for 48 weeks. The adverse reactions with suspected (at least possible) relationship to treatment are listed below by body system organ<br />

class and frequency. Frequencies are defi ned as common (≥ 1/100, < 1/10). See also Post-marketing experience below.<br />

Nervous system disorders:Common: disorders: disorders:Common: headache<br />

Gastrointestinal disorders: Common: diarrhoea,<br />

vomiting, abdominal pain, nausea, abdominal distension, fl atulence Hepatobiliary disorders: Common: ALT increase General disorders and administration site conditions:<br />

Common: fatigue Treatment beyond 48 weeks:<br />

Continued treatment with ten<strong>of</strong>ovir disoproxil fumarate for 96 weeks, in studies GS-US-174-0102 and GS-US-174-0103, did not reveal any new adverse reactions and no change in the tolerability pr<strong>of</strong>i le (nature or severity<br />

<strong>of</strong> adverse events). Exacerbations during treatment: In studies with nucleoside-naïve patients, on-treatment ALT elevations > 10 times ULN (upper limit <strong>of</strong> normal) and > 2 times baseline occurred in 2.6% <strong>of</strong> ten<strong>of</strong>ovir<br />

disoproxil fumarate-treated patients versus 1.9% <strong>of</strong> adefovir dipivoxil-treated patients. Among ten<strong>of</strong>ovir disoproxil fumarate-treated patients, on-treatment ALT elevations had a median time to onset <strong>of</strong> 8 weeks, resolved<br />

with continued treatment, and, in a majority <strong>of</strong> cases, were associated with a ≥ 2 log copies/ml reduction in viral load that preceded or coincided with the ALT elevation. Periodic monitoring <strong>of</strong> hepatic function is<br />

10<br />

recommended during treatment. Post-marketing experience: In addition to adverse reaction reports from clinical studies the following possible adverse reactions have also been identifi ed during post-marketing safety<br />

surveillance <strong>of</strong> ten<strong>of</strong>ovir disoproxil fumarate. Frequencies are defi ned as rare (≥ 1/10,000, < 1/1,000) or very rare (< 1/10,000) including isolated reports. Because these events have been reported voluntarily from a<br />

population <strong>of</strong> unknown size, estimates <strong>of</strong> frequency cannot always be made. Metabolism and nutrition disorders: Rare: lactic acidosis Not known: hypokalaemia<br />

Respiratory, thoracic and mediastinal disorders: Very rare:<br />

dyspnoea Gastrointestinal disorders: Rare: pancreatitis<br />

Hepatobiliary disorders:<br />

Rare: increased transaminases Very rare: hepatitis Not known: hepatic steatosis<br />

Skin and subcutaneous tissue disorders: Rare: rash<br />

Musculoskeletal and connective tissue disorders:<br />

Not known: rhabdomyolysis, osteomalacia (manifested as bone pain and infrequently contributing to fractures), muscular weakness, myopathy<br />

Renal and urinary<br />

disorders:Rare: Rare: acute renal failure, renal failure, proximal renal tubulopathy (including Fanconi syndrome), increased creatinine Very rare: acute tubular necrosis Not known: nephritis (including acute interstitial nephritis),<br />

nephrogenic diabetes insipidus General disorders and administration site conditions: Very rare: asthenia The following adverse reactions, listed under the body system headings above, may occur as a consequence <strong>of</strong><br />

proximal renal tubulopathy: rhabdomyolysis, osteomalacia (manifested as bone pain and infrequently contributing to fractures), hypokalaemia, muscular weakness, myopathy and hypophosphataemia. These events are<br />

not considered to be causally associated with ten<strong>of</strong>ovir disoproxil fumarate therapy in the absence <strong>of</strong> proximal renal tubulopathy. In HBV infected patients, clinical and laboratory evidence <strong>of</strong> exacerbations <strong>of</strong> hepatitis have<br />

occurred after discontinuation <strong>of</strong> HBV therapy (see section 4.4). MARKETING AUTHORISATION HOLDER Gilead Sciences International Limited, Cambridge CB21 6GT, United Kingdom MARKETING AUTHORISATION<br />

NUMBER(S) EU/1/01/200/001 EU/1/01/200/002 DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION Date <strong>of</strong> fi rst authorisation: 5 February 2002 Date <strong>of</strong> last renewal: 7 February 2007 DATE OF<br />

REVISION OF THE TEXT 04/2009 Medicinal product subject to medical prescription €416,75 (€0,00), (€0,00)<br />

• It is recommended that creatinine clearance is calculated in all patients prior to initiating therapy with Viread. • Renal function (creatinine clearance and serum phosphate)<br />

should be monitored every four weeks during the fi rst year and then every three months.• Viread should only be used in patients with impaired renal function if the potential<br />

benefi ts <strong>of</strong> treatment are considered to outweigh the potential risks.• For patients with creatinine clearance <strong>of</strong> < 50 ml/min, adjustment in the dosing interval for Viread<br />

would be required as per the SPC. Viread is not recommended for patients with severe renal impairment (creatinine clearance < 30 ml/min). • Viread should be avoided with<br />

concurrent adefovir dipivoxil or concurrent /recent use <strong>of</strong> a nephrotoxic medicinal product due to the increased risk <strong>of</strong> renal adverse reactions.<br />

090529/16


Thursday 4<br />

room «LiJn» Basl / BlIc<br />

•<br />

sEssION 1<br />

moDErators : s. BOurGEOIs, P. dELTENrE<br />

08.30 A01 characterization <strong>of</strong> the liver progenitor cell niche in liver diseases;<br />

potential involvement <strong>of</strong> WNt and NotcH signaling.<br />

B. spee (1), g. carpino (2), B. schotanus (3), a. katoonizadeh (1), s. Vanderborght (1),<br />

e. gaudio (4), t. roskams (1) / [1] kUleuven, [2] University <strong>of</strong> rome, italy, [3] Utrecht<br />

University, netherlands, [4] sapienza University, rome, italy<br />

08.42 A02 Presence <strong>of</strong> liver angiogenesis and upregulation <strong>of</strong> the vascular<br />

endothelial growth factor (vEgf) in a mice model <strong>of</strong> non-alcoholic<br />

steatohepatitis (NasH).<br />

s. coulon, a. geerts, B. Brouwers, d. Vlaeminck, l. libbrecht, c. Van steenkiste,<br />

f. heindryckx, h. Van Vlierberghe, i. colle / UZ gent<br />

08.54 A03 activation <strong>of</strong> the liver progenitor cell compartment is not sufficient<br />

to ensure liver regeneration.<br />

a.c. dusabineza, J. abarca-Quinones, n. Van hul, i. leclercq / Ucl saint-luc<br />

09.06 A07 angiogenic changes in a new mouse model for hepatocellular<br />

carcinoma assessed with state-<strong>of</strong>-the-art imaging technology.<br />

f. heindryckx (1), B. Vandeghinste (1), n. charette (2), d. slaets (1), l. libbrecht (1),<br />

c. casteleyn (1), s. staelens (1), P. starkel (2), a. geerts (1), i. colle (1),<br />

h. Van Vlierberghe (1) / [1] UZ gent, [2] Ucl saint-luc<br />

09.18 A04 N-glycosylation patterns in Hcc-mice chronically injected with DEN<br />

and their evolution after treatment with anti-Plgf.<br />

B. Blomme, f. heindryckx, i. colle, J.M. stassen, n. callewaert, h. Van Vlierberghe /<br />

UZ gent<br />

09.30 A05 glycogen synthase kinase 3 (gsk3) in immune cells is a major player<br />

INtlr4-mediated cytokine storm in patients with advanced cirrhosis.<br />

t. gustot (1), M. simon-rudler (2), M. fasseu (2), s. gandoura (2), W. abdel-razek (2),<br />

J. deviëre (1), d. lebrec (2), r. Moreau (2) / [1] UlB erasme, [2] inserM, Paris, france<br />

09.42 A06 the ras inhibitor farnesylthiosalicylic acid inhibits Egf and<br />

Igf2-induced cell growth in hepatocarcinoma cell lines.<br />

n. charette, c. de saeger, y. horsmans, i. leclercq, P. starkel / Ucl saint-luc<br />

09.54 A08 liver progenitor cell expansion in the injured mouse liver:<br />

do kupffer cells play a role?<br />

n. Van hul, n. lanthier, J. abarca-Quinones, M. Petit, y. horsmans, i. leclercq / Ucl saint-luc<br />

10.10 A09 2-log drop in viral load at one month: a new stopping rule in<br />

relapsers and non-responders Hcv patients re-treated with<br />

pegylated-IfN and ribavirin?<br />

P. deltenre (1), M. corouge (2), V. canva (2), M. el nady (2), a. louvet (2), h. castel (2),<br />

f. Wartel (2), s. dharancy (2), J. henrion (1), P. Mathurin (2) / [1] hôpital de Jolimont,<br />

haine-saint-Paul, [2] chU lille, france<br />

10.22 c<strong>of</strong>fee breAk<br />

12 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


•<br />

room «LiJn» Basl / BlIc<br />

sEssION 2<br />

moDErators : M. adLEr, h. VaN VLIErBErGhE<br />

10.40 A10 management and outcome <strong>of</strong> biliary complications after liver transplantation.<br />

s. Van cleven, h. Peeters, d. de looze, M. de Vos, a. geerts, X. rogiers, r. troisi,<br />

B. de hemptinne, l. defreyne, P. Vanlangenhove, i. colle, h. Van Vlierberghe / Ugent<br />

10.52 A11 Hepatitis B virus (HBv) infection in Belgium: results <strong>of</strong> the <strong>Belgian</strong><br />

association for the study <strong>of</strong> the liver (basl) registry <strong>of</strong> 1421 HBsag<br />

chronic carriers.<br />

P. deltenre (1), W. laleman (2), M. Van gossum (3), a. lenaerts (4), i. colle (5), M. adler (6), P. Michielsen (7),<br />

c. assene (8), J. delwaide (9), h. orlent (10), h. reynaert (11), f. d_heygere (12), P. langlet (13),<br />

g. robaeys (14), c. de galocsy (15), r. Brenard (16), d. sprengers (17), M.c. Mairlot (18), c. Preux (19),<br />

V. lefèbvre (20), J. henrion (1) / [1] hôpital de Jolimont, haine-saint-Paul, [2] kUleuven, [3] UlB saint-Pierre,<br />

Brussels, [4] chU charleroi, [5] UZ gent, [6] UlB erasme, [7] UZ antwerpen, [8] hôpitaux iris sud Molière,<br />

[9] Ulg sart tilman, [10] aZ sint-Jan, Brugge, [11] VUB UZ Brussels, [12] aZ groeninge, kortrijk,<br />

[13] UlB Brugmann, [14] Zol, genk, [15] hôpitaux iris sud Bracops, [16] hopital st Joseph, gilly,<br />

[17] aZ st-augustinus, Wilrick, [18] clinique saint-Jean, Brussels, [19] chU tivoli, la louvière, [20] chr, namur<br />

11.04 A12 Impact <strong>of</strong> current treatment practice and different scenarios improving<br />

screening, access to treatment and treatment efficacy on Hcvrelated<br />

mortality in Belgium: a mathematical modeling approach.<br />

P. deltenre (1), c. Moreno (2), P. Mathurin (3), M. adler (2), a. louvet (3), h. castel (3),<br />

f. Wartel (3), V. canva (3), J. henrion (1), i. lonjon-domanec (4), s. deuffic-Burban (5) /<br />

[1] hôpital de Jolimont, haine-saint-Paul, [2] UlB erasme, [3] chU lille, france,<br />

[4] Janssen-cilag, issy-les-Moulineaux, france, [5] inserM U795, lille, france<br />

11.16 A13 consequences <strong>of</strong> laparoscopy on liver ischemia during portal triad<br />

clamping in a swine model.<br />

n. gilson, B. nsadi, e. Pire, J.P. cheramy-Bien, J. Pincemail, e. cavalier, c. le g<strong>of</strong>f,<br />

J.o. defraigne, M. Meurisse, o. detry / Ulg sart tilman<br />

11.28 A14 clinicopathological features <strong>of</strong> hepatocellular adenomas classified<br />

according to the bordeaux criteria.<br />

l. libbrecht (1), s. rogge (1), f. heindryckx (1), c. Verslype (2), W. Pauwels (3), r. troisi (1),<br />

a. geerts (1), i. colle (1), h. Van Vlierberghe (1) / [1] UZ gent, [2] kUleuven, [3] st lucas, ghent<br />

11.40 A15 liver transplantation for alcoholic liver disease: a retrospective analysis<br />

<strong>of</strong> recidivism, survival and risk factors predisposing to alcohol relapse.<br />

e. deruytter, c. Van steenkiste, a. geerts, h. Van Vlierberghe, B. de hemptinne, X. rogiers,<br />

r. troisi, f. Berrevoet, i. colle / UZ gent<br />

11.52 A16 Early transplantation improves survival <strong>of</strong> non-responders to corticosteroids<br />

in severe alcoholic hepatitis: a challenge to the 6 month rule <strong>of</strong> abstinence.<br />

c. Moreno (1), V. lucidi (1), n. Bourgeois (1), J. duclos-Vallée (2), J. dumortier (3), V. leroy (4),<br />

t. gustot (1), n. Boon (1), n. clumeck (1), P. deltenre (5), f. Pruvot (6), V. donckier (1), P. Mathurin (6) /<br />

[1] UlB erasme, [2] hôpital Paul Brousse, Villejuif, france, [3] hôpital edouard herriot, lyon, france,<br />

[4] chU grenoble, france, [5] hôpital de Jolimont, haine-saint-Paul, [6] chU lille, france<br />

12.04 2 Basl awards for the Best Basic and clinical Works presented.<br />

12.15 A17 : the Basl-BlIc spring meeting lecture:<br />

“apoptosis, from bench to bedside.” Pr<strong>of</strong>. Marc Bilodeau (Montreal, canada).<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

13<br />

Thursday 4


Thursday 4<br />

room «teun»<br />

•<br />

og-fWo<br />

“ gastroINtEstINal<br />

rEgulatory mEcHaNIsms”<br />

09.00 B01 : Pharmacology <strong>of</strong> inflammatory visceral pain.<br />

P. holzer / graz, austria<br />

09.45 B02 Quantification <strong>of</strong> brain activity evoked by colonic distention in rats<br />

using H215o micro PEt.<br />

M.M. Wouters (1), P. Vermaelen (1), s. Van Wanrooy (1), a. Van santvoort (1),<br />

o. Welting (2), a. nemethova (1), d. Vanderghinste (1), r.M. Van den wijngaard (2),<br />

k. Van laere (1), g.e. Boeckxstaens (1) / [1] kUleuven, [2] aMc amsterdam, netherlands<br />

10.00 B03 long-lasting visceral hypersensitivity following acute tNBs-colitis<br />

in rats.<br />

W. Vermeulen, J. de Man, t. Moreels, s. nullens, P. Pelckmans, B. de Winter / Uantwerp<br />

10.15 B04 Inducible nitric oxide synthase inhibition improves nitrergic<br />

dysfunction in diabetes-prone biobreeding rats.<br />

s. kindt, t. Vanuytsel, s. salim rasoel, W. Boesmans, g. de hertogh, P. Vanden Berghe,<br />

J. tack / kUleuven<br />

10.30 c<strong>of</strong>fee breAk<br />

•<br />

sEssION 1<br />

moDErators : I. dEPOOrTErE, C. dELPOrTE<br />

sEssION 2<br />

moDErators : T. MOrEELs, J. TaCK<br />

11.00 B05 : Pharmacotherapy in somatic pain research<br />

g. hans / antwerp, Belgium<br />

11.30 B06 Intragastric pressure during intragastric nutrient drink infusion as a<br />

novel minimally invasive method to estimate meal-induced gastric<br />

accommodation.<br />

P. Janssen, J. tack / kUleuven<br />

11.45 B07 an increase in intra-gastric pressure is associated with a higher<br />

proximal extent <strong>of</strong> gastroesophageal reflux in healthy volunteers.<br />

k. Blondeau, V. Boecxstaens, r. farre, V. Mertens, a. Pauwels, g. Boeckxstaens, J. tack /<br />

kUleuven<br />

12.00 B08 Effect <strong>of</strong> azD3355, a novel gabab agonist, on reflux and lower<br />

esophageal sphincter function in patients with gErD with symptoms<br />

despite proton pump inhibitor treatment.<br />

g.e. Boeckxstaens (1), h. denison (2), M. ruth (2), J. adler (2), d.g. silberg (2), d. sifrim (3) /<br />

[1] kUleuven, [2] astraZeneca [3] Barts and the london school <strong>of</strong> Medicine and dentistry, U.k.<br />

12.15 B09 Bile acids in sputum <strong>of</strong> patients with cystic fibrosis.<br />

a. Pauwels (1), a. decraene (1), k. Blondeau (1), V. Mertens (1), r. farre (1), l. dupont (1),<br />

d. sifrim (2) / [1] kUleuven, [2] Barts and the london school <strong>of</strong> Medicine and dentistry, U. k.<br />

12.30 LuncH<br />

14 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


•<br />

room «teun»<br />

og-fWo<br />

“ gastroINtEstINal<br />

rEgulatory mEcHaNIsms”<br />

14.00 B10 : development <strong>of</strong> postinflammatory animal models<br />

and visceral hyperalgesia.<br />

n. Vergnolle / toulouse, france<br />

14.45 B11 Endogenous tachykinins modulate distension-induced peristalsis in<br />

the mouse colon mainly through activation <strong>of</strong> Nk1 and Nk2 but not<br />

Nk3 receptors.<br />

a. deiteren, B. de Winter, s. nullens, P. Pelckmans, J. de Man / Uantwerp<br />

15.00 B12 Prucalopride induces transient contraction and facilitates<br />

tachykininergic contractions in guinea pig proximal colon.<br />

f. de Vin (1), M. choi sze (1), J. de Maeyer (2), e. ghoos (2), J. schuurkes (2),<br />

r. lefebvre (1) / [1] heymans institute <strong>of</strong> Pharmacology, gent, [2] Movetis nV, turnhout<br />

15.15 B13 Expression and distribution <strong>of</strong> mas-related gene receptors mrgE and<br />

mrgf in the normal and inflamed murine ileum.<br />

l. avula (1), r. Buckinx (1), k. alpaerts (1), d. adriaensen (1), l. Van nassauw (2),<br />

J.P. timmermans (1) / [1] lab <strong>of</strong> cell Biology and histology, antwerp,<br />

[2] lab <strong>of</strong> cell Biology and histology/lab <strong>of</strong> human anatomy and embryology, antwerp<br />

15.30 B14 Presence <strong>of</strong> functional cgrp receptors on mouse bone<br />

marrow-derived mucosal mast cells.<br />

J. W. rychter (1), l. Van nassauw (2), J.P. timmermans (2), a. B kroese (1) /<br />

[1] UMcU & UU, Utrecht, netherlands, [2] Ua antwerp<br />

15.45 c<strong>of</strong>fee breAk<br />

•<br />

sEssION 3<br />

moDErators : J.P. TIMMErMaNs, G. BOECKXsTaENs<br />

sEssION 4<br />

moDErators : JM. VaNdErWINdEN, r. LEFEBVrE<br />

16.15 B15 role <strong>of</strong> the gPr39 receptor, a member <strong>of</strong> the ghrelin receptor family, in the<br />

regulation <strong>of</strong> glucose homeostasis in a mouse model <strong>of</strong> diet-induced obesity.<br />

P.J. Verhulst, a. lintermans, s. Janssen, J. Buyse, J. tack, i. depoortere / kUleuven<br />

16.30 B16 role <strong>of</strong> ghrelin and ghrelin receptors in the effect <strong>of</strong> bitter taste<br />

receptor agonists on food intake and gastric emptying.<br />

s. Janssen, P.J. Verhulst, J. laermans, J. tack, i. depoortere / kUleuven<br />

16.45 B17 Ic cilium: immun<strong>of</strong>luorescence <strong>of</strong> (immotile) cilium in kit-ir interstitial<br />

cells <strong>of</strong> cajal.<br />

s. ralea, P. gromova, P. hagué, J.M. Vanderwinden / UlB<br />

17.00 B18 Bioengineering <strong>of</strong> circular oesophageal defects<br />

V. coulic (1), V. Maquet (2), P. delree (3), c. deprez (1), s. najar (1), s. Van daele (1) /<br />

[1] UlB Brugmann, Brussels, [2] kitoZyMe, herstal, [3] irsPg gosselies<br />

17.15 End <strong>of</strong> the program<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

15<br />

Thursday 4


Thursday 4<br />

room «sAncY»<br />

•<br />

moDErators : P. dEPrEz, W. VaN sTEENBErGEN<br />

BElgIaN<br />

PaNcrEatIc cluB<br />

09.00 T01 : Pathophysiology <strong>of</strong> inflammatory pancreatic<br />

diseases and its clinical implications.<br />

J.l. frossard / geneva, switzerland<br />

09.30 T02 Impact <strong>of</strong> magnetic resonance cholangiopancreatography in the<br />

work-up <strong>of</strong> pancreatic diseases.<br />

J. rigaux (1), M. arvanitakis (1), M. Bali (1), M. costa Pereira (2), J. devière (1),<br />

M. delhaye (1), c. Matos (1) / [1] UlB erasme, [2] centro hospitalar de lisboa, Portugal<br />

09.45 T03 When Igg4 and ca19-9 yield conflicting results in a patient with<br />

pancreatic disease: lessons to be learned.<br />

W. Van steenbergen, f. claus, r. aerts, t. roskams / kUleuven<br />

10.00 T04 Intrapancreatic metastases: a surgical indication?<br />

g. roeyen, t. chapelle, W. Van riel, k. de greef, B. op de Beeck, J. somville, M. huizing,<br />

d. ysebaert / Ua antwerp<br />

10.15 T05 vascular reconstruction during pancreatoduodenectomy for ductal<br />

adenocarcinoma <strong>of</strong> the pancreas improves resectability but does not<br />

achieve patients cure.<br />

M. ouaissi, c. hubert, a. dili, d. glineur, P. astarci, r. Verhelst, c. sempoux, P. deprez,<br />

i. Borbath, l. annet, y. humblet, M. Van den eynde, P. scalliet, P. g<strong>of</strong>fette, a. loundou,<br />

J.-f. gigot / Ucl saint luc<br />

10.30 c<strong>of</strong>fee breAk<br />

11.00 T06 : screening individuals for pancreatic cancer:<br />

for whom? how? when? and how frequently?<br />

P. deprez / Ucl saint luc<br />

11.30 T07 Ectopic pancreatitis in the antrum, mimicking a submucosal<br />

gastric tumor.<br />

e. Vanhoutte, d. Vanbeckevoort, d. Bielen, k. op de Beeck, r. Vanslembrouck / kUleuven<br />

11.45 T08 coincidental finding <strong>of</strong> primary and metastatic tumours in a Whipple<br />

resection specimen.<br />

l. Verset, a. Mathieu, M. arvanitakis, J. closset, P. loi, M.a. Bali, M. delhaye, P. demetter / UlB erasme<br />

12.00 T09 septicaemic shock in a patient with chronic pancreatitis: report <strong>of</strong> an<br />

unusual case and its successful outcome by endoscopic treatment.<br />

W. Van steenbergen / kUleuven<br />

12.15 T10 Hemosuccus pancreaticus caused by rupture <strong>of</strong> a splenic artery<br />

aneurysm complicating chronic pancreatitis: an uncommon cause<br />

<strong>of</strong> gastrointestinal bleeding.<br />

n. hiltrop, J. hoste, g. lambrecht, a. Janssen, M. cool, g. deboever / aZ damiaan, oostende<br />

12.30 T11 Incidental finding <strong>of</strong> a pancreatic cystic lesion during the postoperative<br />

follow-up <strong>of</strong> a right nephrectomy for renal cell carcinoma.<br />

M. delhaye, M. arvanitakis, M.a. Bali, c. Matos, P. demetter, J. devière, J. closset / UlB erasme<br />

12.45 End <strong>of</strong> the program<br />

16 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


oom «fLorentine» small BoWEl grouP<br />

•<br />

14.00 V01 Perspectives for the 2 nd generation <strong>of</strong> colon capsule.<br />

a. Van gossum / UlB erasme<br />

14.15 V02 spiral enteroscopy versus balloon enteroscopy.<br />

i. demedts / kUleuven<br />

14.30 V03 obscure gastroIntestinal Bleeding (ogIB): algorithm and discussion.<br />

a. Van gossum / UlB erasme and experts from the small Bowel group<br />

•<br />

moDErators : d. dE LOOzE, d. urBaIN<br />

moDErators : C. rEENaErs, E. MaCKEN<br />

15.00 V04 atypical and rare indications <strong>of</strong> small bowel capsule.<br />

d. Urbain / UZ Brussel<br />

15.15 V05 capsule endoscopy for obscure gastrointestinal bleeding in liège:<br />

results and long-term outcome <strong>of</strong> the patients.<br />

s. Bessemans, e. louis, J. Belaiche, c. reenaers / Ulg sart tilman<br />

15.25 V06 single-balloon enteroscopy: multicentric experience in Belgium.<br />

t. Moreels (1), d. Urbain (2) / [1] UZ antwerpen, [2] UZ Brussel<br />

15.45 V07 Impact <strong>of</strong> reimbursement policy in Belgium on the referral pattern<br />

and diagnostic yield <strong>of</strong> capsule endoscopy.<br />

s. de rouck, d. de looze / UZ gent<br />

16.00 End <strong>of</strong> the program<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

17<br />

Thursday 4


Thursday 4<br />

room «LiJn» JoINt mEEtINg<br />

•<br />

sEssION a : shOrT COMMuNICaTIONs<br />

moDErators : J. dELWaIdE, J. LEruT<br />

14.00 D01 Impact <strong>of</strong> tight glycemic control in patients with decompensated<br />

chronic liver disease admitted to intensive care: results <strong>of</strong> a<br />

single-centre randomized controlled trial.<br />

W. laleman, a. Moonen, c. Verslype, P. Meersseman, f. nevens, g. Van den berghe,<br />

a. Wilmer / kUleuven<br />

14.10 D02 liver histology according to the presence <strong>of</strong> the metabolic syndrome<br />

in overweight and obese patients.<br />

a. Verrijken, s. francque, i. Mertens, g. hubens, e. Van Marck, P. Michielsen, l. Van gaal /<br />

UZ antwerpen<br />

14.20 D03 NaflD liver fat score strongly correlates with histological severity <strong>of</strong><br />

NaflD and NasH in a large cohort <strong>of</strong> prospectively included overweight<br />

patients.<br />

s. francque, a. Verrijken, i. Mertens, g. hubens, e. Van Marck, P. Michielsen, l. Van gaal /<br />

UZ antwerpen<br />

14.30 D04 liver transplantation using grafts from donors older than seventy<br />

and eighty years old.<br />

t. darius, d. Monbaliu, W. coosemans, r. aerts, i. Jochmans, J. de roey, B. desschans,<br />

g. Van helleputte, d. claes, W. laleman, W. Van steenbergen, c. Verslype, f. nevens,<br />

J. Pirenne / kUleuven<br />

14.40 D05 urgent early (≤ 15 days) arterial revascularization following hepatic<br />

artery thrombosis may avoid graft loss and improve outcome in adult<br />

liver transplantations.<br />

a. scarinci, M. sainz-Barriga, i. colle, h. Van Vlierberghe, a. geerts, B. Van den Bossche,<br />

f. Berrevoet, X. rogiers, r. troisi, B. de hemptinne / UZ gent<br />

14.50 D06 outcome <strong>of</strong> patients with hepatocellular carcinoma listed for liver<br />

transplantation before and after the mElD allocation system.<br />

B. Vos, c. Moreno, V. lucidi, a. gerkens, a. Buggenhout, n. Bourgeois, V. donckier,<br />

M. adler / UlB erasme<br />

15.00 D07 : marc Hautekeete lecture: «sepsis and cirrhosis»<br />

J.l. Vincent / UlB erasme<br />

15.40 c<strong>of</strong>fee breAk<br />

18 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


•<br />

room «LiJn» JoINt mEEtINg<br />

sEssION B : shOrT COMMuNICaTIONs<br />

moDErators : M. dELhayE, h. rEyNaErT<br />

16.00 D08 Evaluation <strong>of</strong> pancreatic tumors with contrast enhanced-endoscopic<br />

ultrasonography and Eus-strain ratio elastography.<br />

a. Badaoui (1), i. Borbath (2), M. Maffei (2), t. aouattah (2), c. gillain (3), t. de ronde (1),<br />

P. deprez (2) / [1] Ucl Mont-godinne, [2] Ucl saint-luc, [3] hopital st Joseph, gilly<br />

16.10 D09 Endoscopic ultrasound (Eus) guided transluminal drainage <strong>of</strong><br />

pancreatic duct obstruction: long term outcome.<br />

M. ergun, t. aouattah, c. gillain, h. Piessevaux, J.f. gigot, c. hubert, P. deprez /<br />

Ucl saint-luc<br />

16.20 D10 comparison <strong>of</strong> sporadic genetically determined pancreatitis with an<br />

aged matched control group <strong>of</strong> patients with idiopathic pancreatitis.<br />

c. hamoir, X. Pepermans, k. dahan, h. Piessevaux, a. geubel, J.f. gigot, P. deprez /<br />

Ucl saint-luc<br />

16.30 D11 Hepatocellular carcinoma and underlying liver cirrhosis; influence on<br />

treatment or a prognostic value?<br />

c.d. Witjes, r.a. de Man, f.a. eskens, r.s. dwarkasing, P.e. Zondervan, c. Verhoef,<br />

J.n. ijzermans / erasmus Medical center, rotterdam, netherlands<br />

16.40 D12 Is a more agressive surgical management <strong>of</strong> klatskin tumour granted<br />

by better patients : mortality and survival rates?<br />

J.f. gigot, c. hubert, B. radu, c. sempoux, P. deprez, l. annet, P. scalliet, P. g<strong>of</strong>fette /<br />

Ucl saint-luc<br />

16.50 D13 gene expression pr<strong>of</strong>iling <strong>of</strong> circulating pancreatic tumor cells<br />

obtained by a negative depletion strategy.<br />

g. sergeant, r. Van eijsden, t. roskams, V. Van duppen, J. Van Pelt, B. topal / kUleuven<br />

17.00 D14 long-term results <strong>of</strong> adult and paediatric patients operated from<br />

congenital bile duct cysts: a multi-institutional study <strong>of</strong> 98 patients.<br />

c. hubert (1), J.y. Mabrut (2), J. Baulieux (2), c. ducerf (2), e. de la roche (2),<br />

c. Partensky (3), o. Boillot (3), M. audet (3), r. dubois (3), J.P. chappuis (3), c. gouillat (4),<br />

J. lerut (1), r. reding (1), J.B. otte (1), J. de Ville de goyet (1), P.J. kestens (1),<br />

J.f. gigot (1) / [1] Ucl saint-luc, [2] la croix-rousse hospital, lyon, france,<br />

[3] hôpital edouard herriot, lyon, france, [4] hôtel dieu hospital, lyon, france<br />

17.10 D15 management <strong>of</strong> malignant biliary obstruction by endoscopic<br />

ultrasonography-guided drainage.<br />

a. Badaoui (1), c. gillain (2), t. aouattah (3), i. Borbath (3), t. de ronde (1), P. deprez (3) /<br />

[1] Ucl, Mont-godinne, [2] hopital st Joseph, gilly, [3] Ucl saint-luc<br />

17.20 D16 Bacterial DNa is rarely detected in the serum and the ascitic fluid <strong>of</strong> noninfected<br />

outpatients with cirrhosis and ascites treated by paracentesis.<br />

t. serste (1), f. Bert (2), V. leflon (2), c. chauveau (2), t. asselah (2), c. francoz (2), f. durand (2),<br />

d. Valla (2), r. Moreau (2), M. nicolas-chanoine (2) / [1] UlB saint-Pierre, [2] hôpital Beaujon,<br />

clichy, france<br />

17.30 End <strong>of</strong> the session<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

19<br />

Thursday 4


Thursday 4<br />

room «sAncY» IBD<br />

•<br />

14.00 I01 : «Er stress and autophagy».<br />

a. kaser / innsbruck, austria<br />

14.25 I02 Haptoglobin polymorphisms are associated with ulcerative colitis<br />

and crohn’s disease.<br />

l. Márquez, i. cleynen, k. Machiels, s. organe, M. ferrante, l. henkaerts, V. Ballet,<br />

P. rutgeerts, s. Vermeire / kUleuven<br />

14.35 I03 oxigen sensor inhibition attenuates tNf-α induced intestinal epithelial<br />

damage by hypoxia inducible factor (HIf) 1-dependent repression <strong>of</strong><br />

fas-associated death domain protein (faDD).<br />

P. hindryckx, M. de Vos, P. Jacques, l. ferdinande, h. Peeters, k. olivier, B. Brinkman,<br />

P. Vandenabeele, d. laukens / UZ gent<br />

14.45 I04 small animal PEt-ct as a non-invasive method to evaluate terminal<br />

ileal inflammation in a murine model <strong>of</strong> crohn’s disease.<br />

P. hindryckx, s. staelens, s. deleye, h. Peeters, d. laukens, M. de Vos / UZ gent<br />

14.55 I05 Evolution and predictive factors <strong>of</strong> relapse in uc patients treated with<br />

5-asa after a first course <strong>of</strong> systemic steroids.<br />

c. Bello, e. louis, J. Belaiche, c. reenaers / Ulg<br />

15.05 I06 : «Impaired autophagy in crohn’s disease: an opened<br />

15.30<br />

gate to invasive bacteria?».<br />

a. darfeuille-Michaud / clermont-ferrand, france<br />

c<strong>of</strong>fee breAk<br />

•<br />

moDErators : s. VErMEIrE, E. LOuIs<br />

moDErators : d. FraNChIMONT, T. MOrEELs<br />

16.00 I07 : «crohn’s disease: th17 and/or th1 disease?»<br />

16.25 I08<br />

s. Brand / Munich, germany<br />

fatigue in active and quiescent inflammatory bowel disease:<br />

a study investigating its impact on quality <strong>of</strong> life and possible<br />

underlying mechanisms.<br />

h. Peeters, c. de roo, a. Malfait, d. laukens, M. de Vos / UZ gent<br />

16.35 I09 Impact <strong>of</strong> an extensive thiopurine methyltransferase (tPmt)<br />

genotyping in inflammatory bowel disease patients who experienced<br />

myelosuppression during antipurine therapy.<br />

o. dewit (1), t. Moreels (2), f. Baert (3), h. Peeters (4), c. reenaers (5), M. de Vos (4),<br />

P. Van hootegem (6), V. Muls (7), g. Veereman (8), f. Mana (9), J. holvoet (10),<br />

s. naegels (10), M. Van outryve (2), y. horsmans (1), J.l. gala (1) / [1] Ucl saint-luc,<br />

[2] UZ antwerpen, [3] hart hospital roeselare-Menen, [4] UZ gent, [5] Ulg<br />

[6] aZ sint-lucas, Brugge, [7] UlB saint-Pierre, [8] Queen Paola children’s hospital,<br />

antwerpen, [9] VUB UZ Brussel, [10] Zna Middelheim, antwerpen<br />

20 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


oom «sAncY» IBD<br />

16.45 I10 High Infliximab through levels are associated with mucosal healing in<br />

crohn’s disease.<br />

W. Van Moerkercke, c. ackaert, g. compernolle, M. Jürgens, i. cleynen, g. Van assche,<br />

P. rutgeerts, a. gils, s. Vermeire / kUleuven<br />

16.45 I11 lack <strong>of</strong> crP response in patients with active crohn’s disease is characterized<br />

by low Il-6 concentrations but not with genetic variants in the crP gene.<br />

M. Jürgens (1), i. cleynen (1), s. organe (1), f. schnitzler (2), V. Ballet (1), M. noman (1),<br />

g. Van assche (1), P. rutgeerts (1), s. Vermeire (1) / [1] kUleuven [2] University hospital<br />

grosshadern, Munich, germany<br />

17.05 I12<br />

d. elewaut / gent<br />

: «tNfdeltaarE mice: a model to study EIms in cD».<br />

17.30 End <strong>of</strong> the program<br />

•<br />

room «tiffAnY»<br />

BElgIaN HP<br />

stuDy grouP<br />

14.00 H01 the diagnosis <strong>of</strong> resistance <strong>of</strong> H. Pylori by other methods than<br />

culture: what, how, costs and availability<br />

V.y. Miendje deyi / UlB Brugmann<br />

14.25 H02 rescue therapy for H. Pylori<br />

a. Burette / chirec Brussels<br />

14.50 c<strong>of</strong>fee breAk<br />

•<br />

moDErator : P. BONTEMs<br />

moDErator : V. LaMy<br />

15.05 H03 Non conventional therapies for H. Pylori<br />

r. ntounda / UlB saint-Pierre<br />

15.30 H04 some negative aspects <strong>of</strong> PPI<br />

V. Mattens, f. Mana, d. Urbain / UZ Brussel<br />

16.00 End <strong>of</strong> the program<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

21<br />

Thursday 4


Thursday 4<br />

FrIday 5<br />

13H00 -14H00<br />

•<br />

bAsL / bLic<br />

Poster session<br />

rEaDErs for a guIDED tour: J. dELWaIdE, a. GEErTs<br />

A18 a 7 gene set associated with chronic hypoxia <strong>of</strong> universal prognostic<br />

importance in hepatocellular carcinoma.<br />

h. Van Malenstein (1), o. gevaert (1), l. libbrecht (2), a. daemen (1), J. allemeersch (1),<br />

f. nevens (1), e. Van cutsem (1), d. cassiman (1), B. de Moor (1), c. Verslype (1), J. Van Pelt (1) /<br />

[1] kUleuven, [2] UZ gent<br />

A19 the impact <strong>of</strong> elevation <strong>of</strong> total bilirubin level on serum<br />

n-glycosylation patterns in mice and men.<br />

B. Blomme (1), c. Van steenkiste (1), J. Van huysse (2), i. colle (1), n. callewaert (1),<br />

h. Van Vlierberghe (1) / [1] UZ gent, [2] aZ sint-Jan, Brugge,<br />

A20 N-glycosylation patterns <strong>of</strong> serum proteins to make the distinction<br />

between steatosis <strong>of</strong> the liver and non-alcoholic steatohepatitis in<br />

obese patients scheduled for bariatric surgery.<br />

B. Blomme, l. libbrecht, P. Pattyn, y. Van nieuwenhove, d. Van de Putte, a. geerts, i. colle,<br />

n. callewaert, h. Van Vlierberghe / UZ gent<br />

A21 N-glycosylation <strong>of</strong> immunoglobulin g and its role in the alteration<br />

<strong>of</strong> total serum protein N-glycome in two mouse models <strong>of</strong> chronic<br />

liver disease.<br />

B. Blomme, n. callewaert, h. Van Vlierberghe / UZ gent<br />

A22 moderate and excessive alcohol intake impact transplant-free survival:<br />

a longitudinal study in Hcv cirrhotic patients.<br />

P. deltenre (1), M. el nady (2), M. corouge (2), V. canva (2), a. louvet (2), h. castel (2), f. Wartel (2),<br />

s. dharancy (2), J. henrion (1), P. Mathurin (2) / [1] hôpital de Jolimont, haine-saint-Paul,<br />

[2] chU lille, france<br />

A23 occurrence and clinicopathological relevance <strong>of</strong> prognostic markers<br />

(k19, EPcam, and afP) in hepatocellular carcinoma.<br />

o. govaere (1), a. katoonizadeh (1), B. spee (1), f. de luca (2), c. Janssen (1), s. Vander Borght (1),<br />

J. Verheij (3), c. Verslype (1), r. aerts (1), B. topal (1), J. Pirenne (1), f. nevens (1), V. desmet (1),<br />

M. Pinzani (2), t. roskams (1) / [1] kUleuven, [2] University, firenze, italy,<br />

[3] erasmus Medical center, rotterdam, netherlands,<br />

A24 the fibro7-score: a novel serum proteome-and clinical biochemistrybased<br />

predictive model for chronic hepatitis c liver fibrosis.<br />

k.J. cheung, k. tilleman, d. deforce, i. colle, h. Van Vlierberghe / UZ gent<br />

A25 Donation after cardiac death liver transplantation: is donor<br />

age an issue?<br />

o. detry, a. deroover, J.P. squifflet, M.f. hans, B. lambermont, s. lauwick, M. Meurisse, J. delwaide,<br />

P. honoré / Ulg<br />

A26 Hepatitis B-delta virus co-infection in Belgium: joint analysis <strong>of</strong><br />

prospective data <strong>of</strong> the Basl HDv and HBv registries.<br />

e. ho (1), P. deltenre (2), M. nkuize (3), J. delwaide (4), J. henrion (2), r. Brenard (5), c. de galocsy (6),<br />

i. colle (7), f. d heyghere (8), h. orlent (9), P. langlet (10), W. laleman (11), P. Michielsen (1) /<br />

[1] Ua antwerp, [2] hôpital de Jolimont, haine-saint-Paul, [3] UlB saint-Pierre, [4] Ulg,<br />

[5] hopital st Joseph, gilly, [6] ch J. Bracops, Brussels, [7] UZ ghent, [8] aZ groeninge, kortrijk,<br />

[9] aZ sint-Jan, Brugge, [10] UlB Brugmann, [11] kUleuven<br />

22 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


A27 Plasma soluble st2 receptor is increased in human alcoholic liver<br />

disease and correlates with the prognostic index in alcoholic<br />

hepatitis.<br />

a. lemmers, c. Moreno, r. ouziel, d. degré, e. trepo, e. Quertinmont, V. Vercruysse,<br />

o. le Moine, J. devière, t. gustot / UlB erasme<br />

A28 circulating antibodies to commensal bacillus subtilis flagellin as a new<br />

biomarker for bacterial translocation-driven increased microbe-host<br />

interactions in patients with cirrhosis.<br />

t. gustot (1), a. lemmers (1), c. Moreno (1), d. degré (1), r. ouziel (1), d. franchimont (1),<br />

d. lebrec (2), r. Moreau (2), J. devière (1) / [1] UlB erasme, [2] inserM Bichat-Beaujon, Paris, france<br />

A29 vascular hyporeactivity in partial portal vein ligation-induced<br />

portal hypertension is mediated by a specific<br />

cyclooxygenase 2-related mechanism.<br />

s. francque, W. Verlinden, i. Brosius, B. de Winter, a. herman, P.Pelckmans, P. Michielsen /<br />

Ua antwerpen<br />

A30 vascular hyporeactivity in steatosis-induced portal hypertension is<br />

mediated by a specific cyclooxygenase 2-related mechanism.<br />

s. francque, W. Verlinden, i. Brosius, B. de Winter, a. herman, P. Pelckmans, P. Michielsen /<br />

Ua antwerpen<br />

A31 the vasopressin-2-receptor antagonist satavaptan improves portal<br />

hypertension in the non-ascitic thioacetamide cirrhotic rat within a<br />

narrow safe and effective dose-range.<br />

W. laleman (1), J. trebicka (2), l. Van landeghem (1), i. Vander elst (1), t. sauerbruch (2),<br />

d. cassiman (1), f. nevens (1) / [1] kUleuven, [2] University hospital, Bonn, germany<br />

A32 combination therapy with β-carotene and vitamin c significantly ameliorated<br />

biochemical and histological signs in liver damage caused by ccl4 i<br />

ntoxication in rats.<br />

s. Wamutu (1), s. francque (2), s. chatterjee (2), e. Musisi (1), g.W. Muyombya (1), J. Weyler (2),<br />

e. Van Marck (2), g.s. Bimenya (1), P. Michielsen (2) / [1] Makarere University, kampala, Uganda,<br />

[2] Ua, antwerpen<br />

A33 Differential gene expression pr<strong>of</strong>ile in porcine livers subjected to warm<br />

ischemia.<br />

e. Balligand (1), J. Van Pelt (1), Q. liu (1), h. Van Malenstein (1), d. Monbaliu (1), V. heedfeld (1),<br />

t. Wylin (1), t. ayoubi (3), W. Van delm (1), P. Van hummelen (2), J. Pirenne (1), k. Vekemans (1) /<br />

[1] kUleuven, [2] rutgers University, new Jersey, Usa<br />

A34 aldehyde dehydrogenase activity: a new strategy to purify liver<br />

progenitor cells.<br />

l. dollé, J. Mei, J. Best, c. empsen, h. reynaert, a. geerts, l. Van grunsven / VUB<br />

A35 Effects <strong>of</strong> large pore hem<strong>of</strong>iltration in a swine model <strong>of</strong> fulminant<br />

hepatic failure.<br />

o. detry, n. Janssen, e. cavalier, P. delanaye, J.P. cheramy-Bien, P. honoré, J.o. defraigne,<br />

B. lambermont / Ulg<br />

A36 the evolution <strong>of</strong> laparoscopic left lateral sectionectomy without<br />

pringle maneuver: through resection <strong>of</strong> benign and malignant tumors<br />

to living liver donation.<br />

B. Van den Bossche, f. Berrevoet, M. sainz-Barriga, B. de hemptinne, r. troisi / UZ gent<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

23<br />

Thursday 4


2010 XXII nd BElgIaN WEEk <strong>of</strong> gastroENtErology<br />

tHursDay, 4<br />

frIDay, 5<br />

s a t u r D a y ,<br />

6<br />

rooms lIJN tEuN<br />

Morning<br />

lUnch<br />

13h15-14h00<br />

afternoon<br />

17h30-18h15<br />

18h15-19h00<br />

Morning<br />

lUnch<br />

13h15-14h00<br />

afternoon<br />

17h30-18h15<br />

18h15-19h00<br />

Morning<br />

lUnch<br />

afternoon<br />

bAsL / bLic<br />

Joint<br />

meeting<br />

HIltoN<br />

3rD floor<br />

"eXHibition AreA"<br />

Belle ePoQUe rooM<br />

Joint meeting<br />

«eXHibition AreA»<br />

Belle ePoQUe rooM<br />

sAteLLite sYmPosium<br />

soLvAY<br />

Joint meeting<br />

sAteLLite sYmPosium<br />

scHering PLougH<br />

sAteLLite sYmPosium<br />

menArini<br />

og - fwo<br />

og - fwo<br />

sAteLLite sYmPosium<br />

movetis<br />

sAteLLite sYmPosium<br />

giLeAd<br />

sYmPosium <strong>of</strong> tHe 7 societies<br />

«eXHibition AreA»<br />

Belle ePoQUe rooM<br />

sAteLLite sYmPosium<br />

bAYer<br />

sYmPosium <strong>of</strong> tHe 7 societies<br />

24 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


coNfErENcE cENtEr<br />

beLgiAn<br />

PAncreAtic cLub<br />

ibd<br />

reseArcH grouP<br />

bgdo /<br />

rAdioLogY<br />

bgdo /<br />

PAtHoLogY<br />

2ND floor 1st floor<br />

saNcy tIffaNy florENtINE cullINaN III<br />

gi PAtHoLogY cLub<br />

tHe President’s dAY<br />

«eXHibition AreA»<br />

Belle ePoQUe rooM<br />

gi PAtHoLogY cLub<br />

tHe President’s dAY<br />

HP<br />

reseArcH grouP<br />

bsgie /<br />

besPgHAn<br />

smALL boweL<br />

grouP<br />

bgdo /<br />

rAdioLogY<br />

bgdo /<br />

PAtHoLogY<br />

gA srbge<br />

nutrition<br />

grouP<br />

LA / cs<br />

srbge<br />

ActA<br />

gAstroenteroLogicA<br />

beLgicA<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

25<br />

Thursday 4 FrIday 5 saTurday 6


FrIday 5<br />

room «teun/LiJn» JoINt mEEtINg<br />

•<br />

sEssION C : shOrT COMMuNICaTIONs<br />

moDErators : Karen GEBOEs, J.L. VaN LaEThEM<br />

08.30 D17 the “liver first strategy” in stage Iv colorectal cancer disease: the<br />

ghent university hospital experience.<br />

s. laurent (1), k. geboes (1), o. Varin (1), B. Van den Bossche (1), a. scarinci (1), f. Berrevoet (1),<br />

X. rogiers (1), P. Pattyn (1), W. ceelen (1), y. Van nieuwenhove (1), B. de hemptinne (1),<br />

M. Peeters (2), l. libbrecht (1), r. troisi (1) / [1] UZ gent, [2] UZ antwerpen<br />

08.40 D18 Phase II study <strong>of</strong> helical tomotherapy for oligometastatic colorectal cancer.<br />

M. de ridder, B. engels, a. sermeus, h. everaert, B. neyns, h. Vermessen, d. Verellen,<br />

d. Urbain, g. storme / UZ VUB Brussel<br />

08.50 D19 anastomotic complications following Ivor lewis esophagectomy in<br />

patients treated with neoadjuvant chemoradiation are related to<br />

radiation dose to the gastric fundus.<br />

W. ceelen, c. Vande Walle, t. Boterberg, k. geboes, s. laurent, d. Vande Putte,<br />

y. Van nieuwenhove, o. Varin, P. Pattyn / UZ gent<br />

09.00 D20 resection <strong>of</strong> liver metastases after neo-adjuvant treatment with<br />

bevacizumab : the ghent university hospital experience.<br />

k. geboes (1), B. Van den Bossche (1), s. laurent (1), M. craninx (2), B. claerhout (3),<br />

M. hanssens (4), B. Berghmans (4), B. Van overberghe (4), l. Verstraete (4), o. Varin (5),<br />

f. Berrevoet (1), X. rogiers (1), B. de hemptinne (1), c. cuvelier (1), h. Monirath (1),<br />

l. libbrecht (1), M. Peeters (5), r. troisi (1) / [1] Ugent, [2] aZ heilige amilie, reet,<br />

[3] aZ alma, eeklo, [4] aZ sint-elisabeth, Zottegem, [5] UZ antwerp<br />

09.10 D21 spect imaging <strong>of</strong> apoptotic tumor response in a colorectal tumor model.<br />

c. Vangestel (1), n. Van damme (1), g. Mees (2), s. staelens (3), c. Van de Wiele (3),<br />

M. Peeters (4) / [1] UZ gent, [2] UMc, groningen, netherlands, [3] U gent, [4] UZ antwerpen<br />

09.20 D22 Indoleamine 2,3-dioxygenase expression in the tumour invasion front<br />

is an independent prognostic factor in Pt1-4N1mX staged colorectal<br />

cancer.<br />

l. ferdinande (1), a. Mathieu (2), c. decaestecker (2), t. Van Maerken (1), a.M. negulescu (2),<br />

X. Moles lopez (2), c. cuvelier (1), i. salmon (2), P. demetter (2) / [1] UZ gent, [2] UlB erasme<br />

09.30 D23 Endorectal ultrasound and magnetic resonance imaging in staging <strong>of</strong><br />

rectal cancer in routine daily practice.<br />

e. cesmeli (1), k. geboes (1), P.J. de Munck (1), W. ceelen (1), B. claerhout (1),<br />

J. Van ongeval (2), a. de Backer (2), P. smeets (1), P. Pattyn (1), M. Peeters (3), M. de Vos (1) /<br />

[1] UZ gent, [2] st lucas, gent, [3] UZ antwerpen<br />

09.40 D24 lat-1 expression and 4-fmP pet imaging in colorectal cancer.<br />

M. de ridder, B. engels, a. sermeus, h. everaert, B. neyns, h. Vermessen, d. Verellen, d. Urbain,<br />

g. storme / VUB UZ Brussel<br />

09.50 D25 Prognostic significance <strong>of</strong> N stage, nodal harvest, and lymph node<br />

ratio in locally advanced esophageal cancer patients treated with<br />

neoadjuvant chemoradiation.<br />

W. ceelen, c. staelens, l. Maes, V. ochieng, l. libbrecht, t. Boterberg, o. Varin, d. Vande Putte,<br />

y. Van nieuwenhove, P. Pattyn / UZ gent<br />

26 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


•<br />

room «teun/LiJn» JoINt mEEtINg<br />

PLENary sEssION d : BEsT COMMuNICaTIONs<br />

moDErators : h. LOuIs, d. dE LOOzE<br />

10.30 D26 radi<strong>of</strong>requency ablation in Barrett’s esophagus: first <strong>Belgian</strong> safety<br />

and efficacy data.<br />

r. Bisschops (1), t. lerut (1), h. Willekens (1), r. Pouw (2), g. de hertogh (1), J. Bergman (2),<br />

P. nafteux (1), P. rutgeerts (1), g. coremans (1) / [1] kUleuven, [2] aMc, amsterdam, netherlands<br />

10.45 D27 otilonium bromide improves frequency <strong>of</strong> abdominal pain, severity<br />

<strong>of</strong> distention.<br />

J. tack / kUleuven<br />

11.00 D28 Efficacy and tolerability <strong>of</strong> the novel reflux inhibitor, azD3355, as<br />

add-on treatment in patients with gErD with continued symptoms<br />

despite proton pump inhibitor therapy.<br />

g. Boeckxstaens (1), h. Beaumont (2), J.g. hatlebakk (3), d.g. silberg (4), J. adler (4),<br />

h. denison (4) / [1] kUleuven, [2] academic Medical center, amsterdam, netherlands, [3]<br />

haukeland University hospital, Bergen, norway, [4] astraZeneca<br />

11.15 D29 symptom severity and quality <strong>of</strong> life in patients with chronic<br />

constipation: pooled results from three identical randomised<br />

placebo-controlled trials with prucalopride.<br />

d. dubois (1), r. kerstens (2), l. Vandeplassche (2), J. tack (3) /<br />

[1] Patient Value solutions, huldenberg, [2] Movetis, [3] kUleuven<br />

11.30 D30 EsD in Barrett’s esophagus high grade dysplasia and mucosal cancer:<br />

prospective comparison with caP-Emr.<br />

P. deprez, h. Piessevaux, t. aouattah, c.P. yeung, c. sempoux, a. Jouret-Mourin / Ucl saint-luc<br />

11.45 D31 the european achalasia trial: a randomized multi-centre trial<br />

comparing endoscopic pneumodilation and laparoscopic heller<br />

myotomy as primary treatment.<br />

g.e. Boeckxstaens (1), V. annese (2), s. Bruley des Varannes (3), s. chaussade (4), M. costantini (5),<br />

i. elizalde (6), U. fumagalli (7), M. gaudric (4), e. Metman (8), J. Pérez de la serna (9), W.o. roh<strong>of</strong> (10),<br />

a.J. smout (11), J. tack (12), g. Zaninotto (13), o.r. Busch (10) / [1] kUleuven, [2] ospedale cssirccs,<br />

san giovanni rotondo, italy, [3] human nutrition research center, nantes, france, [4] inserM,<br />

Paris, france, [5] University <strong>of</strong> Padua, italy, [6] hospital Barcelona, spain, [7] istituto clinico humanitas,<br />

Milan, italy, [8] hôpital saint antoine, Paris, france, [9] hospital Universitario, Madrid, spain, [10] aMc<br />

amsterdam, netherlands, [11] UMc, Utrecht, netherlands, [12] kUleuven, [13] University Padova, italy<br />

12.00 D32 report (glEm-lok) on current Barrett’s esophagus management in<br />

Belgium : comments and recommendations.<br />

r. Bisschops (kUl), P. deprez (Ucl), J-c. debongnie (ottignies), c. de galoscy (Bracops),<br />

a. elewaut (UZg), r. fiasse (Ucl)<br />

12.15 D33 <strong>Belgian</strong> guidelines for the management <strong>of</strong> upper gI bleeding.<br />

i. colle, J. deflandre, J. delwaide, e. d’hondt, Pf. laterre, o. lemoine, e. Macken, a. Penaloza,<br />

a. Wilmer for the Upper gi bleeding Work group in name <strong>of</strong> the Basl, BesediM, Bsgie, siZ,<br />

srBge and VVge<br />

12.30 Pr<strong>of</strong>essional gastroenterology association<br />

12.45 End <strong>of</strong> morning session<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

27<br />

FrIday 5


FrIday 5<br />

room «teun/LiJn» JoINt mEEtINg<br />

•<br />

PLENary sEssION E : BEsT COMMuNICaTIONs<br />

moDErators : M. hIELE; h. PIEssEVauX<br />

14.00 D34 Early metabolic response evaluation with 18-fDg PEt-ct in ct3-4N+<br />

cancer <strong>of</strong> the oesophagus and gE-junction treated with induction<br />

chemoradiotherapy is not a useful tool to predict histopathological<br />

response and outcome.<br />

g. sergeant, c. deroose, g. de hertogh, J. Moons, W. coosemans, h. decaluwé, g. decker,<br />

P. de leyn, P. nafteux, d. Van raemdonck, l. Mortelmans, a. lerut / kUleuven<br />

14.15 D35 molecular reclassification <strong>of</strong> crohn’s disease by cluster analysis <strong>of</strong><br />

genetic variants.<br />

i. cleynen (1), J. Mahachie John (2), l. henckaerts (1), W. Van Moerkercke (1),<br />

P. rutgeerts (1), k. Van steen (3), s. Vermeire (1) / [1] kUleuven, [2] Ugent, [3] Ulg<br />

14.30 D36 telaprevir (tvr) Q8H or Q12H combined with either peginterferon<br />

(PEg-IfN, P) alfa-2a or alfa-2b and ribavirin (rBv, r) in<br />

treatment-naïve genotype 1 hepatitis c : final results <strong>of</strong> the<br />

randomized, open-label, multicenter phase 2 study c208.<br />

f. nevens (1), y. horsmans (2), h. Van Vlierberghe (3), J. delwaide (4), M. adler (5),<br />

P. Marcellin (6), e. de Paepe (7), s. de Meyer (7), M. Beumont-Mauviel (7) /<br />

[1] kUleuven, [2] Ucl saint-luc, [3] Ugent, [4] Ulg, [5] UlB erasme,<br />

[6] hôpital Beaujon, clichy, france, [7] tibotec bvba<br />

14.35 D37 colorectal EsD may avoid surgery in early neoplasms.<br />

M. Maffei, h. Piessevaux / Ucl saint-luc<br />

15.00 D38 chemotherapy induction followed by preoperative chemoradiation<br />

versus preoperative chemoradiation alone in locally advanced rectal<br />

adenocarcinoma: a randomized controlled phase II study.<br />

r. Maréchal (1), B. Vos (1), M. Polus (2), t. delaunoit (3), M. Peeters (4), P. demeeter (1),<br />

P. coucke (2), B. frederick (5), a. hendlisz (6), a. demols (1), P. Van houtte (6), J. Van de stadt (1),<br />

J.l. Van laethem (1) / [1] UlB erasme, [2] Ulg, [3] hôpital de Jolimont, [4] UZ gent, [5] rhMs,<br />

Baudour, [6] institut Jules Bordet<br />

15.15 D39 malignant tumours and patterns <strong>of</strong> mortality in 200 patients with<br />

primary sclerosering cholangitis (4 to 29 yr follow up).<br />

J. fevery, l. henckaerts, s. Vermeire, P. rutgeerts, f. nevens, W. Van steenbergen / kUleuven<br />

15.30 D40 assessment and prognostic value <strong>of</strong> regression after neoadjuvant therapy<br />

in rectal cancer: the role <strong>of</strong> tumor shrinkage and fragmentation.<br />

M. hav, c. cuvelier, k. geboes, s. laurent, n. Van damme, t. Boterberg, W. ceelen, P. Pattyn,<br />

l. libbrecht / UZ gent<br />

15.45 D41 <strong>Belgian</strong> multicenter experience with the biodegradable ella-stent in<br />

benign strictures <strong>of</strong> the digestive tract. under the auspices <strong>of</strong> the BsgIE.<br />

M. ibrahim (1), a. Vandermeeren (2), V. Van Maele (3), P.h. deprez (4), i. ruytjens (5),<br />

t. Moreels (6), e. Macken (6), J. Verh<strong>of</strong>stadt (7), P. Vergauwe (8), d. de looze (9), o. le Moine (1)<br />

/ [1] UlB erasme [2] chirec-cavell, Brussels, [3] aZ st.lucas, gent, [4] Ucl saint-luc,<br />

[5] Zna Middelheim, antwerpen, [6] UZ antwerpen, [7] Ziekenhuis dendermonde,<br />

[8] aZ groeninge, kortrijk, [9] UZ gent<br />

28 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


oom «teun/LiJn» JoINt mEEtINg<br />

16.00 c<strong>of</strong>fee breAk<br />

•<br />

sEssION F : shOrT COMMuNICaTIONs<br />

moDErators : s. VErMEIrE, T. MOrEELs<br />

16.20 D42 outcome <strong>of</strong> non variceal upper gastrointestinal bleeding<br />

in Belgium.<br />

h. Piessevaux, c. taeter / Ucl saint-luc<br />

Healthcare resource consumption for non-variceal upper<br />

gastrointestinal bleeding in Belgium<br />

h. Piessevaux, c. taeter / Ucl saint-luc<br />

16.40 D43 Intestinal mucosal gene expression <strong>of</strong> endothelial cell adhesion<br />

molecules in patients with inflammatory bowel disease before<br />

and after first infliximab treatment.<br />

i. arijs (1), r. Quintens (1), k. lemaire (1), l. Van lommel (1), k. Van steen (2),<br />

g. de hertogh (1), g. Van assche (1), s. Vermeire (1), k. geboes (1), f. schuit (1),<br />

P. rutgeerts (1) / [1] kUleuven, [2] Ulg<br />

16.50 D44 screening colonoscopy: conventional imaging versus pancolonic<br />

indigo carmine dye.<br />

s. Mouzyka, a. Vinnytska / hospital lissod, kiev, Ukraine<br />

17.00 D45 Diagnostic (dis)agreement between conventional manometry criteria<br />

and the chicago classification <strong>of</strong> esophageal motility disorders in<br />

tertiary care patients.<br />

s. kindt, n. rommel, J. tack / kUleuven<br />

17.10 D46 subclinical intestinal dysbiosis in unaffected first-degree relatives <strong>of</strong><br />

crohn’s disease patients.<br />

M. Joossens (1), g. huys (2), V. de Preter (1), P. rutgeerts (1), P. Vandamme (2),<br />

s. Vermeire (1) / [1] kUleuven, [2] U gent<br />

17.20 D47 comparison <strong>of</strong> complication rates <strong>of</strong> push-type and pull-type<br />

percutaneous endoscopic gastrostomy (peg) in oncology patients.<br />

e. Van dyck, t. Moreels, e. Macken, B. roth, P. Pelckmans / UZ antwerpen<br />

17.30 D48 Efficacy and safety pr<strong>of</strong>ile <strong>of</strong> certolizumab pegol : results from the<br />

compas programme in Belgium.<br />

s. Vermeire (1), k. Vandenbroek (1), M. noman (1), f. Van de Mierop (2), f. Mana (3),<br />

f. Baert (4), e. louis (5), P. caenepeel (6), e. humblet (6), c. claessens (7), g. dhaens (8),<br />

t. Moreels (9), h. Peeters (10), P. Potvin (11), P. Potvin (12), g. Van assche (1), P. rutgeerts (1),<br />

d. franchimont (13) / [1] kUleuven, [2] sint augustinus Ziekenhuis, antwerpen,<br />

[3] UZ VUB Brussel, [4] hart hospital roeselare-Menen, [5] Ulg, [6] Zol, genk, Belgium,<br />

[7] aZ sint-Jozef, turnhout [8] imelda gi clinical research centre, Bonheiden,<br />

[9] UZ antwerpen, [10] UZ gent, [11] Zna Middelheim, antwerpen,<br />

[12] st Jozefkliniek, Bornem, [13] UlB erasme<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

29<br />

FrIday 5


FrIday 5<br />

room<br />

«sAncY/fLorentine»<br />

•<br />

BgDo<br />

raDIology /<br />

PatHology cluB<br />

09.00 P01 Prospective randomized study comparing hepatic intra-arterial injection<br />

<strong>of</strong> yttrium90 resin-microspheres (HaI-y90) with protracted Iv 5fu<br />

(5fu cI) versus 5fu cI alone for patients with liver-limited metastatic<br />

colorectal cancer (lmcrc) refractory to standard chemotherapy (ct).<br />

a. hendlisz (1), M. Van den eynde (2), M. Peeters (3), l. defreyne (3), g. Maleux (4),<br />

J. Vannoote (4), P. delatte (1), M. Paesmans (1), J.l. Van laethem (5), P. flamen (1) /<br />

[1] UlB Bordet, [2] Ucl saint-luc, [3] UZ gent, [4] kUleuven, [5] UlB erasme<br />

09.10 P02 Eus predicts local resection for rectal cancer.<br />

e cesmeli, k. geboes, P.J. de Munck, B. claerhout, W. ceelen, P. Pattyn, d. de looze,<br />

M. Peeters, M. de Vos / UZ gent<br />

09.20 P03 laparoscopic resection <strong>of</strong> colorectal liver metastases: a single center case<br />

control matched-pairs analysis.<br />

B. Van den Bossche, a. scarinci, f. Berrevoet, X. rogiers, l. libbrecht, B. de hemptinne,<br />

r. troisi / UZ gent<br />

09.30 P04 : radionucleide therapy for primary liver tumors.<br />

B. lambert / UZ gent<br />

09.50 P05 : sIrt: Nuclear medicine considerations and pitfalls.<br />

P. flamen / UlB Bordet<br />

10.10 P06 : angiographic considerations in patients<br />

undergoing liver-directed therapies.<br />

g. Maleux / UZ leuven<br />

10.30 Discussion<br />

10.40 c<strong>of</strong>fee breAk<br />

•<br />

sEssION 1: JOINT sEssION <strong>of</strong> radiology / BGdO / Nuclear Medicine society<br />

moDErators : P. sMEETs, C. VErsLyPE<br />

sEssION 2: JOINT session <strong>of</strong> BGdO / Pathology Club<br />

moDErators : I. BOrBaTh, C. CuVELIEr<br />

11.10 P07 a randomized phase II study <strong>of</strong> transarterial chemoembolization with<br />

doxorubicin eluting superabsorbent polymer microspheres in patients<br />

with hepatocellular carcinoma.<br />

h. Van Malenstein, g. Maleux, s. heye, V. Vandecaveye, W. laleman, J. Van Pelt, f. nevens,<br />

c. Verslype / kUleuven<br />

11.20 P08 Intraductal papillary mucinous tumor <strong>of</strong> the bile ducts<br />

k. Van den Bergh, d. Vanbeckevoort, d. Bielen, M. thijs, k. op de beeck, r. Vanslembrouck,<br />

f. claus, t. roland / kUleuven<br />

30 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


oom<br />

«sAncY/fLorentine»<br />

BgDo<br />

raDIology /<br />

PatHology cluB<br />

11.30 P09 correlation between magnetic resonance imaging and pathological<br />

findings after neoadjuvant chemoradiation in rectal cancer.<br />

M. Mertens, c. sempoux, M. habay, f. Zech, a. kartheuser, P. scaillet, y. humblet,<br />

M. Van den eynde, e. danse, a. Jouret-Mourin / Ucl saint-luc<br />

11.40 P10 Dysplasia in fundic gland polyps: what to do?<br />

a. capoen, g. de hertogh, X. sagaert, e. Van cutsem, k. geboes / kUleuven<br />

11.50 P11 revision <strong>of</strong> a series <strong>of</strong> belgian hepatocellular adenoma according to<br />

the bordeaux experience.<br />

d. hoton (1), a. Jouret-Mourin (1), s. dardenne (1), c. hubert (1), J. gigot (1), J. rahier (1),<br />

g. cubel (1), s. godecharles (1), c. Balabaud (2), P. Bioulac- sage (2), c. sempoux (1) /<br />

[1] Ucl saint-luc, [2] University hospital Pellegrin, Bordeaux, france<br />

12.00 P12 : radionucleide therapy for Neuroendocrine tumors:<br />

indications and pitfalls.<br />

c. de roose / UZ leuven<br />

12.30 LuncH<br />

•<br />

sEssION 3: Joint session <strong>of</strong> Pathology Club and BGdO: Kras testing IN GI ONCOLOGy<br />

moDErators : E. VaN CuTsEM, P. PauWELs<br />

14.00 P13 : Emphasis on the key role <strong>of</strong> the pathologist in<br />

kras mutation testing in the selection <strong>of</strong> patients for Egfr-targeted<br />

therapy in colorectal cancer.<br />

a. hoorens (1), a. Jouret-Mourin (2), c. sempoux (2), g. de hertogh (3), P. demetter (4) /<br />

[1] VUB UZ Brussel, [2] Uclouvain, [3] kUleuven, [4] UlB erasme<br />

14.20 P14 kras mutation status in endoscopic and corresponding surgical<br />

biopsies <strong>of</strong> primary sporadic colorectal carcinoma.<br />

a. lemmens, X. sagaert, h. Prenen, k. geboes, s. tejpar, g. de hertogh / kUleuven<br />

14.30 P15 k-ras mutation detection by pyrosequencing in colorectal cancer.<br />

V. slachmuylder, a. Jouret-Mourin, M. heusterspreute, c. sempoux, J.l. gala / Ucl saint-luc<br />

14.40 P16 rapid and sensitive k-ras mutation detection by high resolution<br />

melting analysis and identification by pyrosequencing.<br />

P. Vannuffel, X. deghorain, J.l. dargent / institut de Pathologie et de génétique, gosselies<br />

14.50 P17 kras mutation detection using high resolution melting analysis and<br />

its prognostic value in paraffin-embedded formalin fixed colorectal<br />

cancer tissues.<br />

V. deschoolmeester (1), c. Boeckx (1), M. Baay (1), W. Wuyts (1), e. Van Marck (1),<br />

P. Vermeulen (2), P. Pauwels (1), f. lardon (1), J.B. Vermorken (1), M. Peeters (1) /<br />

[1] UZ antwerpen, [2] sint augustinus Ziekenhuis, antwerpen,<br />

15.00 P18 kras mutation status and colorectal cancer phenotype: is there a<br />

correlation?<br />

g. de hertogh, X. sagaert, k. geboes, a. tertychnyy / kUleuven<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

31<br />

FrIday 5


FrIday 5<br />

room<br />

«sAncY/fLorentine»<br />

BgDo<br />

raDIology /<br />

PatHology cluB<br />

15.10 P19 k-ras mutation in colorectal cancer: an one year experience.<br />

h. el housni, P. de Metter, B. dessars, P. heimann / UlB erasme<br />

15.20 round table :<br />

chairmen : E. Van Cutsem, P. Pauwels<br />

Pannel : A. Jouret-Mourin, Karel Geboes, P. Demetter, S. Tejpar and the speakers<br />

15.40 c<strong>of</strong>fee breAk<br />

16.00 P20 faPa assocatIoN INvItED lEcturE : Diagnostic algorithm <strong>of</strong><br />

lynch syndroom<br />

h. Vasen / leiden, the netherlands<br />

16.30 report <strong>of</strong> gI cancers symposium 2010, orlaNDo - BgDo<br />

Moderators: J.l. Van laethem, J. Janssens<br />

16.30 P21 oesophagogastric cancers:<br />

M. Van den eynde, Ucl saint-luc<br />

16.50 P22 Hepatobiliary and pancreatic cancers:<br />

c. Verslype, kUleuven<br />

17.10 P23 colorectal cancer:<br />

M. Peeters, UZa<br />

17.30 End <strong>of</strong> the program<br />

32 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


•<br />

room «tiffAnY» BsgI E / BEsPgHaN<br />

14.00 E01 foreign bodies extraction.<br />

P. Bontems / UlB hUderf<br />

14.20 E02 sedation and anesthesia in children.<br />

t. Pirotte / Ucl saint-luc<br />

14.40 E03 : Endoscopy for gErD in children.<br />

g. Veereman (1), i. h<strong>of</strong>fman (2) / [1] UZ antwerp, [2] kUleuven<br />

15.00 E04 Endoscopy for gErD in adults (including new techniques).<br />

d. de looze / UZ gent<br />

15.20 E05 Eus in pediatric population: indications, feasibility and impact on<br />

management.<br />

e. toussaint / UlB erasme<br />

15.40 c<strong>of</strong>fee breAk<br />

•<br />

moDErators : P. VaN dEr sPEK, F. sMETs<br />

moDErators : P. dEPrEz, G. VEErEMaN<br />

16.00 E06 Bleeding in children: causes and endoscopic management.<br />

X. stephenne / Ucl saint-luc<br />

16.20 E07 New hemostasis techniques in adults.<br />

P. deprez / Ucl saint-luc<br />

16.40 End <strong>of</strong> the program<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

33<br />

FrIday 5


FrIday 5<br />

room «cuLLinAn iii» NutrItIoN grouP<br />

•<br />

moDErators : J.C. PrEIsEr, d. ysEBaErT<br />

14.00 N01 Nutrition Day 2009 : <strong>Belgian</strong> results.<br />

J.c. Preiser (1) and k Boeykens (2) / [1] chU liège, [2] aZ sint-niklaas<br />

14.12 N02 Nutrition Day 2009: results from a cross-sectional nutritional risk<br />

screening on nineteen hospital wards.<br />

k. Boeykens / aZ sint-niklaas<br />

14.24 N03 utility and limitations <strong>of</strong> nutritional screening in a university hospital.<br />

e. de Waele, s. Mattens, k. delanghe, B. de Waele, g. delvaux / VUB UZ Brussels<br />

14.36 N04 the need for nutritional support in preoperative outpatients.<br />

B. geurden, a. Van Piggelen, n. delmotte, P. Van aken, d. ysebaert / UZ antwerpen<br />

14.48 N05 screening and predicting malnutrition in lung cancer patients: validation<br />

<strong>of</strong> new tools.<br />

n. Barthelemy, a.f. donneau, s. haterte, s. streel, a. albert, M. guillaume / Ulg<br />

15.00 N06 registration <strong>of</strong> nutritional parameters in paper based patient records at<br />

a university Hospital.<br />

B. geurden, c. Wouters, n. delmotte, P. Van aken, d. ysebaert / UZ antwerpen<br />

15.12 N07 risk <strong>of</strong> malnutrition in subjects older than 75 years in Belgium:<br />

results <strong>of</strong> Nutriaction.<br />

M. Vandewoude (2), a. Van gossum (1) / [1] VVkVM, sBnc, domus Medica, ssMg,<br />

[2] nutricia Belgium<br />

15.45 c<strong>of</strong>fee breAk<br />

16.15 N08 Is early enteral nutrition dangerous in acute non-surgical colonic<br />

diverticulitis?<br />

g. Van ooteghem, h. rouviẽre, J.f. gallez, a. el nawar, a. nakad / chWapi notre dame, tournai<br />

16.27 N09 a dietary intervention with arabinoxylan oligosaccharides reduces<br />

colonic protein fermentation in healthy subjects: results from faecal<br />

metabolite fingerprint analysis.<br />

h. hamer, V. de Preter, l. cloetens, g. Vandermeulen, c. courtin, W. Broekaert, J. delcour,<br />

P. rutgeerts, k. Verbeke / kUleuven<br />

16.39 N10 augmenter les variétés des compléments médicaux oraux proposés<br />

(cmo) aux résidents de maisons de repos et maisons de repos et<br />

de soins influence-t-il l’adhésion à la prise de cmo, ainsi que l’état<br />

fonctionnel et la qualité de vie ?<br />

d. Brees / ch libramont<br />

16.51 N11 What can we learn from collecting data about the use <strong>of</strong> parenteral<br />

nutrition ?<br />

V. lievin, s. Vereecken, a. Ballarin, s. de Breucker, t. Pepersack, M. arvanitakis, J. Berre,<br />

a. Van gossum / UlB erasme<br />

17.03 N12 could we administer drugs along with parenteral nutrition? results <strong>of</strong> a<br />

survey.?<br />

a.Van gossum, a. Ballarin, V. lievin / UlB erasme<br />

17.15 End <strong>of</strong> the program<br />

34 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


www.rs-communication.be<br />

PM/PM/09/003/NF<br />

MAAGSAPRESISTENTE TABLETTEN - 20/40 MG<br />

COMPRIMÉS GASTRO-RÉSISTANTS - 20/40MG


FrIday 5<br />

13H00 -14H00<br />

•<br />

Joi nt m eeti ng:<br />

Poster session<br />

rEaDErs for a guIDED tour: M. arVaNITaKIs, P. PELCKMaNs<br />

D49 serum adiponectin strongly correlates with the degree <strong>of</strong> steatosis<br />

and inflammation but not fibrosis in a prospectively included cohort<br />

<strong>of</strong> NaflD patients.<br />

s. francque (1), a. Verrijken (1), i. Mertens (1), M.r. taskinen (2), g. hubens (1), e.Van Marck (1),<br />

P. Michielsen (1), l. Van gaal (1) / [1] UZ antwerpen [2] helsinki University central hospital and<br />

Biomedicum, finland<br />

D50 minimally invasive oesophagectomy: a valuable alternative to open<br />

oesophagectomy for the treatment <strong>of</strong> early oesophageal and<br />

gastro-oesophageal junction carcinoma.<br />

P. nafteux, J. Moons, W. coosemans, h. decaluwé, g. decker, P. de leyn, d. Van raemdonck, t. lerut<br />

/ kUleuven<br />

D51 Extent <strong>of</strong> liver resection in caroli’s disease: a multi-institutional<br />

retrospective study <strong>of</strong> 33 patients.<br />

c. hubert (1), J.y. Mabrut (2), c. Partensky (3), e. oussoultzoglou (4), d. Jaeck (4), J. Baulieux (2),<br />

o. Boillot (3), J. lerut (1), J.B. otte (1), J. de Ville de goyet (1), M. audet (3), c. ducerf (2),<br />

J.f. gigot (1) / [1] Ucl saint-luc, [2] la croix-rousse hospital, lyon, france, [3] hôpital edouard<br />

herriot, lyon, france, [4] hautepierre hospital, strasbourg, france<br />

D52 Is the use <strong>of</strong> Iv gadolinium mandatory in liver mrI for characterizing<br />

focal liver lesions as benign or malignant?<br />

M. antic (1), a. schiettecatte (1), d. Verdries (1), B. op de beeck (2), f. Vandenbroucke (1),<br />

s. dymarkowski (3), J. de Mey (1), M. dujardin (1) / [1] VUB UZ Brussels, [2] UZ antwerpen, [3] kUleuven<br />

D53 combined liver and kidney transplantation.<br />

t. serste (1), t. darius, d. Monbaliu, r. aerts, t. roskams, e. lerut, d. cassiman, c.Verslype,<br />

W. laleman, y. Vanrenterghem, f. nevens, J. Pirenne / kUleuven<br />

D54 liver transplantation for adult polycystic liver disease.<br />

t. darius (1), a. Patris (2), d. Monbaliu (1), e. Bonaccorsi (2), r. aerts (1), W. coosemans (1),<br />

t. roskams (1), Z. hassoun (2), o. ciccarelli (2), y. Pirson (2), y. Vanrenterghem (1), f. nevens (1), J. lerut<br />

(2), J. Pirenne (1) / [1] kUleuven, [2] Ucl saint-luc<br />

D55 a muticenter internal audit about following guidelines on osteoporosis<br />

prevention and detection in gI disease.<br />

d. Baert / Maria Middelares Ziekenhuis, gent<br />

D56 liver transplantation for hepatocellular failure after biliopancreatic<br />

diversion (scopinaro) or jejuno-ileal by-pass for weight reduction :<br />

a <strong>Belgian</strong> survey.<br />

a. geerts (1), t. darius (2), t. sablon (1), r. aerts (2), t. chapelle (3), g. roeyen (3), l. libbrecht (1),<br />

t. roskams (2), f. nevens (2), s. francque (3), J. Pirenne (2), r. troisi (1) / [1] Ugent, [2] kUleuven,<br />

[3] Uantwerp<br />

D57 laparoscopic cholecystectomy in acute cholecystitis: evidence to<br />

support a proposal for an early interval surgery<br />

k. Boterbergh, f. Berrevoet, i. adriaenssens, h. Peeters, e. de Wolf, B. Van den bossche,<br />

X. rogiers, B. de hemptinne, r. troisi, a. de croo / U gent<br />

D58 Wilson’s disease: long-term follow-up <strong>of</strong> a cohort <strong>of</strong> twenty-four<br />

patients treated with D-penicillamine.<br />

k. lowette, k. desmet, P. Witters, W. laleman, c. Verslype, f. nevens, J. fevery, d. cassiman / kUleuven<br />

36 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


BsGIE Meeting : Poster session<br />

D59 Weight reduction by means <strong>of</strong> an intragastric balloon in daily<br />

routine practice: results at removal and in long-term.<br />

e. cesmeli (1), h. troubleyn (2), M. daems (3), c. tuyttens (1), d. Vansteenkiste (1), t. onghena (1) /<br />

[1] aZ st. lucas, gent, [2] kUleuven, [3] st lucas, gent<br />

D60 the role <strong>of</strong> single-balloon endoscopy in diagnostics and minimally invasive<br />

treatment <strong>of</strong> patients with a clinical suspicion <strong>of</strong> obscure bleeding.<br />

e. ivanova, e. fedorov, M. tim<strong>of</strong>eev, o. yudin, P. tcherniakevich / Moscow University hospital,<br />

Moscow, russia<br />

D61 single-balloon enteroscopy in patients with small bowel abnormalities.<br />

e. fedorov, e. ivanova, M. tim<strong>of</strong>eev, o. yudin / Moscow University hospital, Moscow, russia<br />

D62 acute appendicitis after colonoscopy: an underevaluated complication?<br />

e. Vanderstraeten, d. Baert, e. Monsaert, k. rasquin, P. Burvenich / aZ Maria Middelares, gent<br />

D63 causes <strong>of</strong> non-resection <strong>of</strong> polyps during colonoscopy in hospitalized<br />

patients.<br />

M.a. denis, c. oxfort, k. azzouzi, o. dewit, h. Piessevaux, P. hoang, a. Uytterhoeven, P. deprez /<br />

Ucl saint-luc<br />

D64 Prospective comparison <strong>of</strong> full thickness resection <strong>of</strong> submucosal tumours<br />

with and without a new grasping device to help triangulation : the endolifter.<br />

P. deprez, J. navez, B. navez, J.f. gigot, e. legrand, P. gianello, c.P. yeung / Ucl saint-luc<br />

IBd Meeting : Poster session<br />

XXII 37<br />

nd D65 Differential mucosal expression <strong>of</strong> tH17 related genes in the small and<br />

large bowel <strong>of</strong> IBD patients.<br />

s. Bogaert, d. laukens, h. Peeters, M. lode, k. olievier, J. Vandesompele, d. elewaut, M. de Vos / Ugent<br />

D66 Defining endoscopic response in crohn’s disease.<br />

M. ferrante, M. noman, s. Vermeire, g. Van assche, P. rutgeerts / kUleuven<br />

D67 adalimumab improves work productivity for patients with<br />

moderately to severely active crohn’s disease: subgroup analysis<br />

<strong>of</strong> belgian patients in the care trial.<br />

e. louis (1), f. Baert (2), t.g. Moreels (3), g. d’haens (4), g. Van assche (5), o. dewit (6), M. devos (7),<br />

k. grosfils (8), n. chen (8), M. yang (8), P. Mulani (8), J. chao (8) / [1] Ulg, [2] hart hospital roeselare-<br />

Menen, roeselare, [3] UZ antwerp, [4] imelda gi clinical research centre, Bonheiden, [5] kUleuven,<br />

[6] Ucl saint-luc, [7] Ugent, [8] aBBott diagnostics<br />

D68 adalimumab for induction and maintenance <strong>of</strong> remission in<br />

anti-tNf–naïve and anti-tNf–exposed crohn’s disease patients<br />

in the care study: results from Belgium.<br />

e. louis (1), f. Baert (2), o. dewit (3), g. Van assche (4), g. d’haens (5), t. Moreels (6), a. robinson (7),<br />

M. kron (7), P. Pollack (7) / [1] Ulg, [2] heilig hartziekenhuis, roeselare, [3] Ucl, [4] kUleuven,<br />

[5] imelda gi clinical research centre, Bonheiden, [6] UZ antwerp, [7] aBBott<br />

D69 Impaired butyrate oxidation in ulcerative colitis is due to decreased<br />

butyrate uptake and a defect in the oxidation pathway.<br />

V. de Preter, g. Vandermeulen, P. rutgeerts, k. Verbeke / kUleuven<br />

D70 IBD and month <strong>of</strong> birth.<br />

J.M. ghilain, M. Vanderh<strong>of</strong>stadt, M. schapira, J.M. ghilain, o. descamps / hôpital de Jolimont, haine-saint-Paul<br />

D71 Plasma octanoylated ghrelin levels in young children with<br />

gastroesophageal reflux disease (gErD) and food refusal.<br />

e. dierckx (1), s. annemans (1), s. staelens (1), e. de Wever (1), i. depoortere (2),<br />

g. Veereman-Wauters (1) / [1] Queen Paola children’s hospital, antwerpen, [2] kUleuven<br />

• <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

FrIday 5


saTurday 6<br />

room «teun/LiJn»<br />

•<br />

ovEr aND uNDEr NutrItIoN<br />

08.50 Introduction:<br />

g. d’haens<br />

moDErators : J. CLOssET, h. VaN VLIErBErGhE<br />

sEvEN socI EtI Es<br />

symPosIum<br />

09.00 S01 gastrointestinal complications <strong>of</strong> overnutrition.<br />

i. leclercq / Ucl saint-luc<br />

09.25 S02 Bariatric surgery: from surgical techniques to metabolic changes.<br />

g. Präger / Vienna, austria<br />

09.55 S03 metabolic complications <strong>of</strong> bariatric surgery.<br />

a. geerts / UZ gent<br />

10.15 S04 Endoscopic treatment <strong>of</strong> obesity.<br />

P. swain / london, U.k.<br />

10.40 c<strong>of</strong>fee breAk<br />

•<br />

moDErators : d. ysEBaErT, a. VaN GOssuM<br />

11.00 S05 should we still use diets in gastroenterology?<br />

e. Mathus-Vliegen / amsterdam, the netherlands<br />

11.25 S06 short bowel syndrome: from acute to chronic?<br />

W. Van gemert / Maastricht, the netherlands<br />

11.50 S07 role <strong>of</strong> nutritional support in cancer cachexia<br />

J.-M. argilés / Barcelona, spain<br />

12.15 S08 awards:<br />

12.50 LuncH<br />

- BWGE Basic and Clinical Awards<br />

- BGDO Award<br />

- IBD Prize<br />

38 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


oom «teun/LiJn»<br />

•<br />

moDErators : M. hIELE, M. sCaILLON<br />

sEvEN socI EtI Es<br />

symPosIum<br />

14.15 S08 anorexia Nervosa<br />

M. Vandewoude / tienen<br />

14.40 S09 Nutritional aspects <strong>of</strong> “Eras” (enhanced recovery after surgery)<br />

M. von Meyenfeldt / Maastricht, the netherlands<br />

15.05 S10 Nutritional aspects in liver diseases<br />

c. Verslype / kUleuven<br />

15.30 S11 PEg and PEJ-tubes: not only a technical procedure<br />

i. duysburgh / sint-niklaas<br />

15.55 S12 guidelines for the use <strong>of</strong> parenteral nutrition in gastroenterology<br />

(starting from case discussions)<br />

a. Van gossum / UlB erasme<br />

17.15 End <strong>of</strong> the symposium<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

39<br />

saTurday 6


saTurday 6<br />

room<br />

«sAncY/tiffAnY»<br />

09.00 WElcomE<br />

•<br />

gI PatHology cluB:<br />

tHE PrEsIDENt’s Day<br />

«tIBI valE DIcImus»<br />

09.15 P24 Eosinophilic esophagitis versus reflux esophagitis.<br />

a. enzari / tUrQUey<br />

09.45 P25 Intestinal metaplasia in the endoscopic gastroesophageal junction<br />

versus short segment Barrett’s esophagus.<br />

J.f. flejou / france<br />

10.15 P26 gastric cancer and mimics <strong>of</strong> gastric cancer.<br />

f. carneiro / PortUgal<br />

10.45 c<strong>of</strong>fee breAk<br />

11.00 P27 significance <strong>of</strong> IE lymphocytes in the small bowel.<br />

V. Villanacci / italy<br />

11.30 P29 zinc in gastrointestinal disease.<br />

g. faa / italy<br />

12.00 P28 two different views for a same lesion: Endoscopy versus Histology.<br />

g. lauwers / Usa<br />

12.30 LuncH<br />

•<br />

moDErators : P. dEPrEz, P. VaN EyKEN<br />

moDErators : a. drIEssEN, J.F. COLOMBEL<br />

14.00 P30 colitis mimicking IBD.<br />

n. shepherd / Uk<br />

14.30 P31 Dysplasia in IBD.<br />

B. riddell / canada<br />

15.00 P32 the perfect pathologist? an endoscopist’s vision.<br />

P. rutgeerts / BelgiUM<br />

15.30 P33 Pathologic predictors <strong>of</strong> microsatellite instability in colorectal cancer.<br />

J. greenson / Usa<br />

16.00 P31 conclusion<br />

40 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


BR 8593 - 01/2009


frIDay NIgHt Party<br />

at the « appelmans Brasserie »<br />

on Friday March 5, 2010 at 8.00pm<br />

Venue : Papenstraatje 1, 2000 antwerp<br />

The <strong>Belgian</strong> <strong>Week</strong> steering Committee is looking forward to<br />

welcoming all the registered participants and partners to the<br />

Friday Night Party !<br />

The aperitive and dinner will take place at the «appelmans Brasserie<br />

and absinthbar» with delicious food, and nice music. Everything is<br />

there for an enchanting evening!<br />

Make sure to join us and register on the websites :<br />

www.belgianweek.be or www.bwge.be<br />

the appelmans Brasserie is at a walking distance (50 m)<br />

<strong>of</strong> the hilton hotel.<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

43<br />

Thursday 4 FrIday 5 saTurday 6


Thursday 4<br />

FrIday 5<br />

saTurday 6<br />

takE mE to HIltoN aNtWErP<br />

Itinerary<br />

address :<br />

hilton antwerp hotel<br />

groenplaats – 2000 antwerp<br />

tel: +32 3 204 12 12<br />

fax: +32 3 204 86 88.<br />

From antwerp Central station (max 10min) walking.<br />

1. Please leave the train station by the main entrance.<br />

2. follow the street in front <strong>of</strong> the main entrance, “de keyserlei” until you reach a big crossroad which<br />

you need to cross.<br />

3. follow the “Meir” (shopping street) on the other side until the end.<br />

4. at the end <strong>of</strong> the “Meir” you will see the “kBc” tower.<br />

5. cross the street on the right side <strong>of</strong> the “Meir” to reach the “eiermarkt”.<br />

6. follow the “eiermarkt” until the end where the main entrance <strong>of</strong> the hilton antwerp is.<br />

From antwerp Central station (max 10min) by tram.<br />

1. Please go to level -1 in the train station. follow the sign ‘M’ Metro<br />

2. Please take the tam 15 or 2, direction groenplaats<br />

3. get <strong>of</strong>f the tram at station groenplaats<br />

4. follow the exit groenplaats shopping center<br />

5. you will arrive in the groenplaats Parking or on the groenplaats square<br />

6. follow the “eiermarkt” until the end where the main entrance <strong>of</strong> the hilton antwerp is.<br />

By car :<br />

Coming from Ghent (E17)<br />

1. immediately after the kennedytunnel take exit nr. 5a direction antwerpen centrum-Zuid.<br />

2. select the left lane and turn left at the traffic lights.<br />

3. again select the left lane and go straight ahead at the next traffic lights.<br />

4. after the flashing amber you see a big blue building on your left side. there you take the second street<br />

on your right (Vlaamse kaai).<br />

5. at the end <strong>of</strong> the Vlaamse kaai you turn right.<br />

6. at the fourth traffic light you turn right, this street is called ‘suikerrui’.<br />

7. on the suikerrui after the first traffic lights you take a very sharp turn to the right.<br />

8. in front <strong>of</strong> you you will see the hilton antwerp and the underground parking ‘groenplaats’. from the<br />

parking there is a direct connection to the hilton antwerp lobby.<br />

44 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


Coming from Eindhoven/hasselt (E34/E313)<br />

1. at the end <strong>of</strong> the e34/e313 you take the first exit 5a on the ring, direction antwerpen centrum Zuid<br />

(antwerp center south)<br />

2. select the left lane and turn left at the traffic lights.<br />

3. again select the left lane and go straight ahead at the next traffic lights.<br />

4. after the flashing amber you see a big blue building on your left side. there you take the second street<br />

on your right (Vlaamse kaai).<br />

5. at the end <strong>of</strong> the Vlaamse kaai you turn right.<br />

6. at the fourth traffic light you turn right, this street is called ‘suikerrui’.<br />

7. on the suikerrui after the first traffic lights you take a very sharp turn to the right.<br />

8. in front <strong>of</strong> you you will see the hilton antwerp and the underground parking ‘groenplaats’. from the<br />

parking there is a direct connection to the hilton antwerp lobby.<br />

Coming from Brussels (E19)<br />

1. in the craeybeckxtunnel take the left lane direction antwerpen centrum.<br />

2. at the traffic lights straight ahead (generaal lemanstraat).<br />

3. at the second traffic lights turn left (Jan van rijswijcklaan).<br />

4. at the next traffic lights turn right (lange lozannastraat).<br />

5. after the fourth traffic leights you cross the Boulevard and arrive in the kasteelpleinstraat. the road<br />

makes a left turn and becomes kronenburgstraat. follow this road.<br />

6. at the next traffic lights turn right (nationalestraat)<br />

7. go straight on.<br />

8. you arrive at the groenplaats. Please park your car in the car park groenplaats right in front <strong>of</strong> you.<br />

there is a direct access from the car park into the hotellobby.<br />

9. the main entrance <strong>of</strong> the hotel is on the eiermarkt.<br />

Coming from Brussels via Boom (a12)<br />

1. follow the a12 direction antwerpen. Before the tunnel choose the left lane direction<br />

antwerpen-centrum.<br />

2. Please follow direction antwerpen centrum – Zuid .<br />

3. see point 2 coming from gent.<br />

Coming from zelzate, Linkeroever<br />

1. follow the signs direction antwerpen<br />

2. take the Waaslandtunnel (under the schelde). right after you exit the tunnel make a sharp turn to<br />

the right this is the Vlaamse kaai.<br />

3. at the end <strong>of</strong> the Vlaamse kaai you turn right.<br />

4. at the fourth traffic light you turn right, this street is called ‘suikerrui’.<br />

5. on the suikerrui after the first traffic lights you take a very sharp turn to the right.<br />

6. in front <strong>of</strong> you you will see the hilton antwerp and the underground parking ‘groenplaats’. from the<br />

parking there is a direct connection to the hilton antwerp lobby.<br />

Coming from Breda (E19)/ Bergen op zoom (E34/a12)<br />

1. at the intersection antwerpen-noord you follow the a12 direction Bergen op Zoom.<br />

2. take exit 16 ekeren.<br />

3. at the traffic lights take left (noorderlaan) direction antwerpen – haven 1-100.<br />

4. you are now on the noorderlaan.<br />

5. follow this road for about 4.5km.<br />

6. at the end <strong>of</strong> the noorderlaan ( the road makes a turn <strong>of</strong> 45° on a bridge) you arrive at traffic lights.<br />

stay completely right.<br />

7. you arrive in the londonstraat, go straight ahead to the riverside. at the t crossing after the lights turn left.<br />

8. you are now on the riverside.<br />

9. turn left at the third traffic lights, suikerrui. straight ahead over the oude koornmarkt and the kammenstraat.<br />

10. at the first trafficlight take a sharp turn left on to the nationalestraat. you arrive at the groenplaats<br />

with the underground car park right in front <strong>of</strong> you. you have an immediate access from the car park<br />

into the hotellobby.<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

45<br />

Thursday 4 FrIday 5 saTurday 6


Thursday 4<br />

FrIday 5<br />

saTurday 6<br />

NotEs<br />

46 XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010


NotEs<br />

XXII nd • <strong>Belgian</strong> <strong>Week</strong> <strong>of</strong> gastroenterology • antWerP, March 4-6 2010<br />

47<br />

Thursday 4 FrIday 5 saTurday 6


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