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Poisons and Drugs

Lecture1 pdf - Professor Monzir Abdel-Latif

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Uncertainty (safety) factors<br />

A threshold of exposure above which an adverse<br />

effect can occur <strong>and</strong> below which no such effect is<br />

observed, is obtained from available data.<br />

The threshold of exposure is then divided by a<br />

factor (uncertainty or safety factor) to lower it to a<br />

new value that toxicologists can regard as safe<br />

beyond doubt.

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