03.11.2015 Views

Asthma Therapeutics in Major Developed Markets Growth & Trend to 2020 Radiant Insights, Inc

Summary Radiant Insights, a leading business intelligence provider, has released its latest research report,"Asthma Therapeutics in Major Developed Markets to 2020 - Personalized Treatment for Severe Asthma to Drive Market Growth despite Patent Expirations".The asthma therapeutics market is forecast to grow marginally over the forecast period across the top eight developed nations, from $18.4 billion in 2013 to a projected value of $21.7 billion by 2020 at a Compound Annual Growth Rate (CAGR) of 2.4%. This is in spite of generic erosion facing several of the leading asthma brands, such as Advair (fluticasone propionate/salmeterol xinafoate), Symbicort (budesonide/formoterol fumarate) and Xolair (omalizumab), and is a consequence of new market entrants and rising disease prevalence. The global prevalence of asthma is significant, believed to affect approximately 300 million people worldwide. This burden is predicted to increase in future, reaching 400 million by 2025. Access This Full Report @ http://www.radiantinsights.com/research/asthma-therapeutics-in-major-developed-markets-to-2020-personalized-treatment-for-severe-asthma-to-drive-market-growth-despite-patent-expirations Although the majority of asthma patients are able to manage their symptoms effectively using currently marketed products, some remain inadequately controlled with these same products. This unmet need, coupled with rising global prevalence, has resulted in strong industry interest. Consequently, the current asthma pipeline is highly innovative, featuring several promising molecules in late-stage drug development. Biologics and monoclonal antibodies, the latter in particular, are gaining prominence within the indication. Novel monoclonal antibodies such as mepolizumab, reslizumab, lebrikizumab, and dupilumab target Interleukins (IL), or IL receptors, and have demonstrated potential in severe and inadequately controlled eosinophilic asthma, in turn representing a shift towards personalized therapy. Despite the fact that they target only a small patient sub-set, they are likely to be priced highly and to drive market growth, offsetting the impact of generic erosion.

Summary

Radiant Insights, a leading business intelligence provider, has released its latest research report,"Asthma Therapeutics in Major Developed Markets to 2020 - Personalized Treatment for Severe Asthma to Drive Market Growth despite Patent Expirations".The asthma therapeutics market is forecast to grow marginally over the forecast period across the top eight developed nations, from $18.4 billion in 2013 to a projected value of $21.7 billion by 2020 at a Compound Annual Growth Rate (CAGR) of 2.4%. This is in spite of generic erosion facing several of the leading asthma brands, such as Advair (fluticasone propionate/salmeterol xinafoate), Symbicort (budesonide/formoterol fumarate) and Xolair (omalizumab), and is a consequence of new market entrants and rising disease prevalence.

The global prevalence of asthma is significant, believed to affect approximately 300 million people worldwide. This burden is predicted to increase in future, reaching 400 million by 2025.

Access This Full Report @ http://www.radiantinsights.com/research/asthma-therapeutics-in-major-developed-markets-to-2020-personalized-treatment-for-severe-asthma-to-drive-market-growth-despite-patent-expirations

Although the majority of asthma patients are able to manage their symptoms effectively using currently marketed products, some remain inadequately controlled with these same products. This unmet need, coupled with rising global prevalence, has resulted in strong industry interest.

Consequently, the current asthma pipeline is highly innovative, featuring several promising molecules in late-stage drug development. Biologics and monoclonal antibodies, the latter in particular, are gaining prominence within the indication. Novel monoclonal antibodies such as mepolizumab, reslizumab, lebrikizumab, and dupilumab target Interleukins (IL), or IL receptors, and have demonstrated potential in severe and inadequately controlled eosinophilic asthma, in turn representing a shift towards personalized therapy. Despite the fact that they target only a small patient sub-set, they are likely to be priced highly and to drive market growth, offsetting the impact of generic erosion.

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Table 3: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Global, Classification of <strong>Asthma</strong> Severity <strong>in</strong> Youths ≥ 12 Years of<br />

Age and Adults 15<br />

Table 4: Management of Chronic <strong>Asthma</strong> 16<br />

Table 5: Management of Acute <strong>Asthma</strong> 18<br />

Table 6: <strong>Asthma</strong> Cl<strong>in</strong>ical Trial Endpo<strong>in</strong>ts 19<br />

Table 7: <strong>Asthma</strong> <strong>Therapeutics</strong>, Global, All Pipel<strong>in</strong>e Products, Discovery Phase, 2015 118<br />

Table 8: <strong>Asthma</strong> <strong>Therapeutics</strong>, Global, All Pipel<strong>in</strong>e Products, Precl<strong>in</strong>ical Phase, 2015 119<br />

Table 9: <strong>Asthma</strong> <strong>Therapeutics</strong>, Global, All Pipel<strong>in</strong>e Products, Phase I, 2015 124<br />

Table 10: <strong>Asthma</strong> <strong>Therapeutics</strong>, Global, All Pipel<strong>in</strong>e Products, Phase II, 2015 125<br />

Table 11: <strong>Asthma</strong> <strong>Therapeutics</strong>, Global, All Pipel<strong>in</strong>e Products, Phase III, 2015 127<br />

Access This Full Report @ http://www.radiant<strong>in</strong>sights.com/research/asthma-therapeutics-<strong>in</strong>major-developed-markets-<strong>to</strong>-<strong>2020</strong>-personalized-treatment-for-severe-asthma-<strong>to</strong>-drive-marketgrowth-despite-patent-expirations<br />

Table 12: <strong>Asthma</strong> <strong>Therapeutics</strong>, Global, All Pipel<strong>in</strong>e Products, Pre-registration Phase, 2015 128<br />

Table 13: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Global, Market Forecast, 2013–<strong>2020</strong> 128<br />

Table 14: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, US, Market Forecast, 2013–<strong>2020</strong> 129<br />

Table 15: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Canada, Market Forecast, 2013–<strong>2020</strong> 129<br />

Table 16: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, UK, Market Forecast, 2013–<strong>2020</strong> 129<br />

Table 17: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, France, Market Forecast, 2013–<strong>2020</strong> 130<br />

Table 18: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Germany, Market Forecast, 2013–<strong>2020</strong> 130<br />

Table 19: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Italy, Market Forecast, 2013–<strong>2020</strong> 130<br />

Table 20: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Spa<strong>in</strong>, Market Forecast, 2013–<strong>2020</strong> 131<br />

Table 21: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Japan, Market Forecast, 2013–<strong>2020</strong> 131<br />

List of Figures<br />

Figure 1: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Global, Heat Map for Marketed Products, 2015 42<br />

Figure 2: <strong>Asthma</strong> <strong>Therapeutics</strong> Market, Global, Heat Map for Marketed Products (cont<strong>in</strong>ued), 2015 42

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