Global Hospital-acquired Pneumonia Drugs Market Details Analysis
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<strong>Global</strong> <strong>Hospital</strong>-<strong>acquired</strong> <strong>Pneumonia</strong> <strong>Drugs</strong> <strong>Market</strong><br />
to Stand at US$3.8 bn by 2020 fueled by Imminent<br />
Launches<br />
The incidence of healthcare associated pneumonia or global hospital-<strong>acquired</strong> pneumonia drugs<br />
market is showing a progressive increase; however, the multidrug resistance shown by<br />
microorganisms that cause nosocomial infections has created a large market for drugs that treat<br />
hospital-<strong>acquired</strong> pneumonia. According to the report, six major phase III drugs will collectively<br />
generate revenue to the tune of US$3.8 bn by 2020.<br />
The appreciable demand for hospital-<strong>acquired</strong> pneumonia falls into perspective when one<br />
considers the fact that pneumonia accounts for over 22% of all hospital-<strong>acquired</strong> infections.<br />
Often, conventional antibiotics are unable to treat multidrug resistant organisms, creating a<br />
sizeable unmet demand for effective drugs for not just hospital-<strong>acquired</strong> pneumonia but also for<br />
other kinds of hospital <strong>acquired</strong> infections.<br />
However, the astounding amounts of money spent on combating hospital-<strong>acquired</strong> drugs has<br />
forced governments to impose strict policies to address the root causes of such infections. As<br />
many of these programs meet success, the incidence rate of hospital-<strong>acquired</strong> infections will<br />
likely see a dip. This will, in turn, lead to a decline in the demand for hospital-<strong>acquired</strong><br />
pneumonia drugs. The report terms this trend as an impending restraint for the growth of the<br />
global hospital-<strong>acquired</strong> pneumonia drugs market.<br />
<strong>Hospital</strong>-<strong>acquired</strong> pneumonia, which is also sometimes referred to as ventilator-associated<br />
pneumonia, is typically seen among patients who are immunocompromised patients, on enteral<br />
feeding, or have undergone surgery. Infants, too, face a risk of acquiring hospital-<strong>acquired</strong><br />
pneumonia. Among the newborn, respiratory syncytial virus (RSV) is identified as being the<br />
major cause of nosocomial pneumonia.<br />
The global hospital-<strong>acquired</strong> pneumonia drugs market currently features one vaccine and five<br />
investigational drugs in clinical trials phase III. It is estimated that many of these drugs will hit<br />
the market in 2017. The following drugs are currently in phase III of clinical trials, as per the<br />
report: Cubist Pharmaceuticals’ Ceftolozane/tazobactam and tedizolid phosphate, AstraZeneca<br />
PLC’s Ceftazidime/avibactam, Bayer Healthcare’s Amikacin inhale, Achaogen, Inc.’s<br />
Plazomicin, and GlaxoSmithKline’s Synflorix. Of these, tedizolid phosphate is emerging as the<br />
most preferred drug for treating nosocomial pneumonia.
TMR’s analysis reveals that many of the candidates that are expected to be launched over the<br />
coming years are biological drugs. With this, it can be gauged that a paradigm shift is taking<br />
place from traditional antibiotic therapy to more sophisticated biological drug therapy. With four<br />
drug candidates for hospital-<strong>acquired</strong> pneumonia, the pipeline of Aridis Pharmaceuticals is seen<br />
to be the strongest, and each of these drugs is a monoclonal antibody therapy.<br />
In addition to these drugs, the market also features ten drugs that are in the early clinical trial<br />
stages. The market is characterized by numerous research and development activities.Companies<br />
that currently hold a strong position in the global hospital <strong>acquired</strong> pneumonia drugs market are:<br />
Achaogen, Inc., AstraZeneca PLC, Aridis Pharmaceutical, Valneva SE, Bayer Healthcare,<br />
Basilea Pharmaceutica Ltd., Cubist Pharmaceutical, Meiji Seika Pharma Co., Ltd.,<br />
GlaxoSmithKline, and Merck & Co.<br />
<strong>Global</strong> <strong>Hospital</strong> Acquired <strong>Pneumonia</strong> Drug Pipeline, Late Stage Candidates (Phase III)<br />
Tedizolid phosphate<br />
Ceftolozane/tazobactam<br />
Ceftazidime/avibactam<br />
Amikacin inhale<br />
Plazomicin<br />
Synflorix<br />
<strong>Global</strong> <strong>Hospital</strong> Acquired <strong>Pneumonia</strong> Drug Pipeline, Early Stage Candidates (Phase II,<br />
Phase I and Preclinical Trials)<br />
AR-101 or KBPA101<br />
GSK 2189242A<br />
BAL30072<br />
MEDI4893<br />
AR 301 or KBSA301<br />
ME1100<br />
V114<br />
AR-104 or KBPA104<br />
AR-201 or KBRV201<br />
AR-401 or KBAB401<br />
Browse Full Press Release on <strong>Hospital</strong>-<strong>acquired</strong> <strong>Pneumonia</strong> <strong>Drugs</strong> <strong>Market</strong>:<br />
Press Release
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