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Short and Simple
Short: Mean duration of treatment — 5.4 days 1*
Simple: Only GnRH antagonist available in a
ready-to-use pre-fi lled syringe 1
• Rapidly absorbed —
approximately 1 hour after dosing 1
• Rapidly reversible —
within 48 hours of discontinuation,
pituitary hormones (LH and FSH)
are fully recovered 1
• Small injection volume – 0.5 mL 1
• Room temperature storage 1
*Results from a multicenter, open-label randomized study to assess the effi cacy and safety of
Ganirelix Acetate Injection in women undergoing controlled ovarian hyperstimulation. Range 2-14 days.
Ganirelix Acetate Injection is indicated for the inhibition of premature LH surges in women undergoing controlled
ovarian hyperstimulation.
SELECTED SAFETY INFORMATION
• Ganirelix Acetate Injection is contraindicated in patients with a known hypersensitivity to Ganirelix Acetate or to any
of its components, to GnRH or any other GnRH analog, and in patients with known or suspected pregnancy.
• Only physicians experienced in infertility treatment should prescribe Ganirelix Acetate Injection. Before starting
treatment with Ganirelix, pregnancy must be excluded.
• Cases of hypersensitivity reactions, including anaphylactoid reactions with the fi rst dose, have been reported during
post-marketing surveillance. The packaging of this product contains natural rubber latex which may cause
allergic reactions.
• The most common adverse events occurring in ≥1% of patients treated with Ganirelix in clinical trials (N=794) include:
abdominal pain (gynecological) 4.8%, fetal death 3.7%, headache 3.0%, ovarian hyperstimulation syndrome (OHSS)
2.4%, vaginal bleeding 1.8%, injection site reaction 1.1%, nausea 1.1%, abdominal pain (gastrointestinal) 1.0%.
Please see adjacent page for brief summary of full Prescribing Information.
Reference: 1. Ganirelix Acetate Injection [package insert]. Roseland NJ: Organon USA Inc.
Copyright © 2010, N.V. Organon, a subsidiary of Merck & Co., Inc. All rights reserved. Printed in USA. GX2046 8/10