European Committee on Antimicrobial Susceptibility Testing

Recommendations

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Kingella kingae EUCAST Clinical Breakpoint Tables v. 7.0, valid from 2017-01-01 Macrolides and lincosamides MIC breakpoint (mg/L) Disk content Zone diameter breakpoint (µg) (mm) S ≤ R > S ≥ R < Azithromycin 0.25 1 0.25 1 Note A Note A Clarithromycin 0.5 1 0.5 1 Note A Note A Erythromycin 0.5 0.5 15 20 20 Clindamycin - - - - Notes Numbered notes relate to general comments and/or MIC breakpoints. Lettered notes relate to the disk diffusion method. 1. Susceptibility can be inferred from erythromycin susceptibility. A. Infer susceptibility from erythromycin susceptibility. Tetracyclines MIC breakpoint (mg/L) Disk content Zone diameter breakpoint (µg) (mm) S ≤ R > S ≥ R < Doxycycline 0.5 1 0.5 1 Note B Note B Tetracycline 0.5 0.5 30 28 28 Notes Numbered notes relate to general comments and/or MIC breakpoints. Lettered notes relate to the disk diffusion method. 1/B. Isolates susceptible to tetracycline are also susceptible to doxycycline, but some resistant to tetracycline may be susceptible to doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required. Miscellaneous agents MIC breakpoint (mg/L) Disk content Zone diameter breakpoint (µg) (mm) S ≤ R > S ≥ R < Rifampicin 0.5 0.5 5 20 20 Trimethoprim-sulfamethoxazole 1 0.25 0.25 1.25-23.75 28 28 Notes Numbered notes relate to general comments and/or MIC breakpoints. Lettered notes relate to the disk diffusion method. 1. Trimethoprim:sulfamethoxazole in the ratio 1:19. Breakpoints are expressed as the trimethoprim concentration. 83
Mycobacterium tuberculosis EUCAST Clinical Breakpoint Tables v. 7.0, valid from 2017-01-01 Listed breakpoints have been set in parallel with marketing authorisation by EMA. Breakpoints for other agents have not yet been established. Recommended methods for antimicrobial susceptibility testing of mycobacteria are currently under discussion. MIC breakpoint (mg/L) Notes Numbered notes relate to general comments and/or MIC breakpoints. S ≤ R > Delamanid 0.06 0.06 Bedaquiline 0.25 0.25 84
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European C
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Guidance on reading EUCAST Breakpoi
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Version 7.0, 2017-01-01 Acinetobact
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Enterobacteriaceae EUCAST Clinical
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Pseudomonas spp. EUCAST Clinical Br
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Pseudomonas spp. EUCAST Clinical Br
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Acinetobacter spp. EUCAST Clinical
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Acinetobacter spp. EUCAST Clinical
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Staphylococcus spp. EUCAST Clinical
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Enterococcus spp. EUCAST Clinical B
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Enterococcus spp. EUCAST Clinical B
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Streptococcus groups A, B, C and G
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Page 43 and 44: Viridans group streptococci EUCAST
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Page 47 and 48: Haemophilus influenzae EUCAST Clini
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Page 57 and 58: Neisseria gonorrhoeae EUCAST Clinic
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Page 61 and 62: Neisseria meningitidis EUCAST Clini
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Page 65 and 66: Gram-positive anaerobes except Clos
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Page 75 and 76: Listeria monocytogenes EUCAST Clini
Page 77 and 78: Pasteurella multocida EUCAST Clinic
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European Committee on Antimicrobial Susceptibility Testing

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