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Dan Mayer Essential Evidence-based Medicine

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The medical literature: an overview 31<br />

(4) Finally, the discussion should address all potential biases in the study and<br />

hypothesize on their effects on the study conclusions. The directions for<br />

future research in this area should then be addressed.<br />

Conclusion<br />

The study results should be accurately reflected in the conclusion section, a<br />

one-paragraph summary of the final outcome. There are numerous points that<br />

should be addressed in this section. Notably, important sources of bias should be<br />

mentioned as disclaimers. The reader should be aware that pitfalls in the interpretations<br />

of study conclusions include the use of biased language and incorrect<br />

interpretation of results not supported by the data. Studies sponsored by drug<br />

companies or written by authors with other conflicts of interest may be more<br />

prone to these biases and should be regarded with caution. All sources of conflict<br />

of interest should be listed either at the start or at the end of the article.<br />

Bibliography<br />

The references/bibliography section demonstrates how much work from other<br />

writers the author has acknowledged. This includes a comprehensive reference<br />

list including all important studies of the same or similar problem. You will<br />

be better at interpreting the completeness of the bibliography when you have<br />

immersed yourself in a specialty area for some time and are able to evaluate this<br />

author’s use of the literature. Be wary if there are multiple citations of works by<br />

just one or two authors, especially if by the author(s) of the current study.<br />

How can you get started?<br />

You have to decide which journals to read. The New England Journal of <strong>Medicine</strong><br />

is a great place for medical students to start. It publishes important and high<br />

quality studies and includes a lot of correlation with basic sciences. There are<br />

also excellent case discussions, review articles, and basic-science articles. In general,<br />

begin by reading the abstract. This will tell you if you really want to read this<br />

study in the first place. If you don’t care about this topic, go on to the next article.<br />

Remember, that what you read in the abstract should not be used to apply<br />

the results of the study to a clinical scenario. You still need to read and evaluate<br />

the article, especially the methods section. JAMA (Journal of the American Medical<br />

Association) is another excellent journal with many studies regarding medical<br />

education and the operation of the health-care system. For readers in the United<br />

Kingdom, the Lancet and the BMJ (British Medical Journal) are equivalent journals<br />

for the student to begin reading.

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