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Treating Infantile Hemangiomas in Children

PubMedHealth_PMH0088999

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Steroids<br />

• Methylprednisolone (Medrol®) and prednisolone (Flo-Pred®,<br />

Prelone®) help treat the IH <strong>in</strong> at least 4 out of every 10 children.<br />

• Triamc<strong>in</strong>olone (Kenalog®) may help treat the IH <strong>in</strong> at least 5 out of<br />

every 10 children, but more research is needed to know this for sure.<br />

• The beta-blocker popranolol (Hemangeol) works better than<br />

steroids to treat IHs.<br />

What are the possible side effects of medic<strong>in</strong>es to treat an IH?<br />

Medic<strong>in</strong>e (Brand Name)<br />

Beta-Blockers<br />

Propranolol (Hemangeol)<br />

by mouth<br />

Timolol* (Timoptic-XE®) gel drops<br />

Atenolol (Tenorm<strong>in</strong>®) by mouth<br />

Nadolol (Corgard®) by mouth<br />

Steroids<br />

Methylprednisolone (Medrol®)<br />

by mouth<br />

Prednisolone (Flo-Pred®,<br />

Prelone®) by mouth<br />

Triamc<strong>in</strong>olone (Kenalog®) shot<br />

Possible side effects listed by the FDA <strong>in</strong>clude:<br />

• Trouble sleep<strong>in</strong>g<br />

• Cold hands and feet<br />

• Diarrhea<br />

• Nausea<br />

• Vomit<strong>in</strong>g<br />

• Mood changes<br />

• Problems with growth<br />

• Roundness of the face<br />

• Increased appetite<br />

• Weight ga<strong>in</strong><br />

• Fluid retention (body tissues<br />

hold extra water)<br />

• Low blood pressure<br />

• A slow heartbeat<br />

• Trouble breath<strong>in</strong>g, such as wheez<strong>in</strong>g<br />

• Low blood sugar (may also keep<br />

symptoms of low blood sugar from<br />

show<strong>in</strong>g up)<br />

• Changes <strong>in</strong> the way the body uses<br />

glucose (sugar)<br />

• High blood pressure<br />

• Increased risk of <strong>in</strong>fection<br />

The triamc<strong>in</strong>olone (Kenalog®) shot<br />

can also cause:<br />

• Changes <strong>in</strong> sk<strong>in</strong> color<br />

• Th<strong>in</strong>n<strong>in</strong>g of the sk<strong>in</strong><br />

* Because timolol (Timoptic-XE®) is put on the sk<strong>in</strong> <strong>in</strong>stead of taken by mouth or as a shot, it may cause fewer side effects.<br />

Note: It is important to talk with your child’s health care professional about the safety of<br />

medic<strong>in</strong>es to treat your child’s IH. Accord<strong>in</strong>g to the FDA:<br />

»»<br />

Beta-blockers should not be taken by children who have:<br />

––<br />

Wheez<strong>in</strong>g or other breath<strong>in</strong>g problems<br />

––<br />

A slow heartbeat<br />

––<br />

Certa<strong>in</strong> heart problems<br />

»»<br />

Propranolol (Hemangeol) should not be taken by children who:<br />

––<br />

Weigh less than 4.5 pounds<br />

––<br />

Have low blood pressure<br />

»»<br />

The steroid shot triamc<strong>in</strong>olone (Kenalog®) should not be taken by children who are<br />

younger than 3 weeks old.<br />

6

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