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<strong>Empresas</strong> <strong>Andrómaco</strong> Andr <strong>Andrómaco</strong> maco <strong>Overview</strong><br />
March 22nd March 22 , 2010 nd , 2010<br />
1
Corporate Profile<br />
� <strong>Empresas</strong> <strong>Andrómaco</strong> is one of the leading pharmaceutical companies along the Pacific Coast of Latin<br />
America, with strong manufacturing, marketing and distribution networks for medicines, nutritional<br />
products and medical supplies.<br />
� The Company positions itself as a Pharmaceutical Marketing Company, specialized in Prescription and<br />
specialized healthcare products, for private an public markets, recognized by the quality and efficiency<br />
of commercial management.<br />
� The Company has a strong capacity to create high demand in private and institutional markets, based<br />
on experience, quality, and extensive outreach to medical professionals.<br />
� Sales force of over 600 professionals<br />
� The Company provides effective and efficient marketing channels including promotion throughout the<br />
health care industry, among consumers, through trade organizations and existing sales and distribution<br />
networks.<br />
� <strong>Empresas</strong> <strong>Andrómaco</strong> is the best strategic partner for international companies interested in developing<br />
their pharmaceutical business in Latin America.<br />
2
History<br />
1927 � Laboratorios <strong>Andrómaco</strong> was founded in Spain<br />
1942 � <strong>Andrómaco</strong> launches operations in Chile<br />
1979 � <strong>Andrómaco</strong> separates from Spanish parent company and merges with Chilean laboratories<br />
1993 � First branch ABL Pharma Bolivia is opened<br />
2002 � <strong>Andrómaco</strong> achieves GMP certification from the Public Health Institute (ISP) of Chile<br />
2002 � New strategic approach EMPRESAS ANDROMACO<br />
2004 � <strong>Andrómaco</strong> initiates share offering on Chilean stock market<br />
2004 � The Ferrer‐Andromaco joint‐venture is inaugurated<br />
2005 � <strong>Empresas</strong> <strong>Andrómaco</strong> buys Laboratorio Silesia<br />
2005 � <strong>Andrómaco</strong> laboratories receives its second GMP certification from the ISP of Chile<br />
2005 � <strong>Empresas</strong> <strong>Andrómaco</strong> achieves CENABAST certification<br />
2006 � <strong>Andrómaco</strong> Laboratories receives INVIMA certification for all production lines<br />
2006 � <strong>Andrómaco</strong> is ranked as number two laboratory in Chile in units<br />
2007 � ABL Pharma Dominican Republic begins operations<br />
2007 � <strong>Andrómaco</strong> buys IPROFASA in Guatemala<br />
2007 � MasterCare is founded<br />
2008 � 80% of Diagnotec is acquired<br />
2008 � <strong>Andrómaco</strong> opens the first Biofarmaceutical Center to be approved in Chile<br />
2009 � Number 1 supplier public sector<br />
3
Property Structure<br />
� Open joint‐stock company marketed in the<br />
Commerce Stock Exchange of Santiago.<br />
� Risk classification<br />
� Feller Rate: first Class, Level 3<br />
� Fitch Chile: first Class, Level 3<br />
Sahrehoders Shares %<br />
INVERSIONES NM LIMITADA 196,189,121 35.0%<br />
MONEDA SA AFI PARA PIONERO FONDO DE INVERSION 80,679,000 14.4%<br />
FONDO DE INVERSION LARRAIN VIAL BEAGLE 37,301,079 6.7%<br />
CELFIN SMALL CAP CHILE FONDO DE INVERSIO 33,588,822 6.0%<br />
MONEDA SA AFI PARA COLONO FONDO DE INVERSION 33,357,000 6.0%<br />
COMPASS EMERGENTE FONDO DE INVERSION 28,655,760 5.1%<br />
CELFIN CAPITAL S A C DE B 25,293,664 4.5%<br />
CHILE FONDO DE INVERSION SMALL CAP 19,960,453 3.6%<br />
INVERSIONES MARDOS SA 15,000,000 2.7%<br />
SIGLO XXI FONDO DE INVERSION 9,542,950 1.7%<br />
MONEDA SA AFI PARA MONEDA CHILE FUND LTD 8,928,000 1.6%<br />
LARRAIN VIAL S A CORREDORA DE BOLSA 7,204,024 1.3%<br />
Sub Total 495,699,873 88.43%<br />
Other 64,840,673 11.57%<br />
Total 560,540,546 100.00%<br />
Corporate Ownership<br />
US$/share<br />
0.40<br />
0.35<br />
0.30<br />
0.25<br />
0.20<br />
0.15<br />
0.10<br />
0.05<br />
sep‐04<br />
NM Private<br />
Investor<br />
35%<br />
Other Share‐<br />
holders<br />
24%<br />
ene‐05<br />
0.2<br />
may‐05<br />
0.2<br />
sep‐05<br />
ene‐06<br />
0.23<br />
may‐06<br />
sep‐06<br />
ene‐07<br />
0.38 0.37<br />
may‐07<br />
sep‐07<br />
ene‐08<br />
Moneda<br />
Investment<br />
Funds<br />
22%<br />
Celfin<br />
Investment<br />
Funds<br />
11%<br />
Larrain Vial<br />
Inv. Funds<br />
8%<br />
0.29<br />
may‐08<br />
sep‐08<br />
0.16<br />
ene‐09<br />
0.29<br />
may‐09<br />
sep‐09<br />
4<br />
0.32<br />
ene‐10<br />
CLP/USD = 510
Financial Highlights<br />
Corporate Sales<br />
(dollars in thousands)<br />
$ 103,400<br />
$ 133,100<br />
$ 146,200 $ 162,200 $ 172,900 $ 172,800<br />
2004 2005 2006 2007 2008 2009<br />
EBITDA<br />
(dollars in thousands)<br />
$ 15,000<br />
$ 20,600<br />
$ 21,700<br />
$ 23,400 $ 23,500<br />
$ 31,500<br />
2004 2005 2006 2007 2008 2009<br />
Net Income<br />
(dollars in thousands)<br />
$ 7,900<br />
$ 8,500<br />
$ 11,600<br />
$ 10,900<br />
$ 5,200<br />
$ 16,400<br />
2004 2005 2006 2007 2008 2009<br />
Operating Profit<br />
(dollars in thousands)<br />
$ 11,100<br />
$ 15,400<br />
Non operational<br />
loss mainly due to<br />
exchange rate and<br />
organizational<br />
restructure<br />
$ 18,500 $ 19,700 $ 18,800<br />
$ 25,600<br />
2004 2005 2006 2007 2008 2009<br />
CLP/USD = 510<br />
5
Product Divisions<br />
Rx Marketing Division<br />
� Represents 45% of total sales.<br />
� Subsidiaries (Silesia, MasterCare, ABL Pharma)<br />
are focused primarily in prescription<br />
medications.<br />
� Cardiology, Neuropsychiatry, Genecology,<br />
Dermatology, Pediatrics and Hospital drugs<br />
represent some of our primary strategic<br />
therapeutic areas.<br />
OTC‐UTC Division<br />
� Represents 23% of Chilean national sales and<br />
19% of corporate sales.<br />
� 2nd leading OTC provider in Chile.<br />
� Solid competency in direct‐to‐consumer and<br />
trade marketing.<br />
Generics Division<br />
� 25% of total Chilean national sales.<br />
� More than 180 presentations.<br />
� 2nd leading generics provider in Chile.<br />
Chile Pharma Sales by Product Division<br />
(dollars in millions)<br />
$ 33<br />
$ 37<br />
$ 34<br />
$ 69<br />
$ 68<br />
$ 67<br />
$ 30<br />
$ 34<br />
$ 37<br />
Generic Rx UTC+OTC Clinic<br />
Products<br />
� Strong recognition, satisfaction and<br />
acceptance among doctors and patients.<br />
� Products manufactured through total quality<br />
and GMP industrial methodologies certified by<br />
Chile and Colombia.<br />
� In addition to its own highly regarded<br />
proprietary products, <strong>Andrómaco</strong> provides a<br />
wide range of recognized and prominent<br />
licensed products.<br />
$ 1<br />
2007<br />
2008<br />
2009<br />
$ 2<br />
6
Licenses and Strategic Alliances<br />
Corporate Pharma Sales 2009<br />
(dollars)<br />
Generic<br />
Prods<br />
20%<br />
OTC+UTC<br />
Prods<br />
22%<br />
Licensed<br />
Prescription<br />
Prods<br />
16%<br />
Propietary<br />
Prescription<br />
Prods<br />
42%<br />
� <strong>Empresas</strong> <strong>Andrómaco</strong>’s partners have ready<br />
access to comprehensive and efficient<br />
marketing to medical professionals throughout<br />
the region.<br />
� The Company has received licenses from over<br />
50 leading pharmaceutical companies for the<br />
Central and South American market for more<br />
than 125 products.<br />
� Argentina: Gador, Phoenix, Andromaco Argentina<br />
� Austria: Reisenberger GmbH<br />
� Canada: Pharmascience<br />
� Chile: Biosano<br />
� Costa Rica: Newport<br />
� Denmark: Lundbeck, Novonordisk, Nycomed, Leo, Statem<br />
Serum<br />
� France: Pierre Fabre Dermocosmetic, Pierre Fabre<br />
Medicament, Fournier<br />
� Germany: Sankyo, Schwabbe, Grünenthal, Fujisawa, AMG Int.<br />
� India: Cipla, Claris, Dr. Reddys, Gland Pharma, Ind‐Swit Ltd,<br />
Pure, Ranbaxy<br />
� Italy: Alfawasserwan, Boehringer Ingelheim Italy, Chiesi,<br />
Foltene, Recordati, Rottapharm, SPA<br />
� Japan: Hisamitsu, Taisho, Mitsubishi<br />
� Mexico: Aplicaciones Farmacéuticas<br />
� Neatherlands: Nutricia<br />
� Spain: Bioibérica, Eurogine, Ferrer, Isdin, Lab. Esteve, Lab.<br />
Viñas, Phivor, Robert, Uriach<br />
� Switzerland: Helsinn, Om, TRB Chemedica, Vifor<br />
� United States: Mallinkrodt, Host Pharma,Gen Probe,Three<br />
Rivers Pharmaceuticals<br />
7
Commercial Approach<br />
� Physician<br />
� Provide clinical and therapeutic research information to doctors allowing them access to updated<br />
pharmaceutical knowledge.<br />
� One on one marketing according to their profile and prescription preferences.<br />
� Institutional Clinical MD and personnel<br />
� Patient<br />
� Create exceptional added value with novel healthcare solutions for institutional markets.<br />
� Offer a broad range of high quality products and commit to excellence in service<br />
� Understand our product consumers, go ahead of their needs and provide informative and<br />
educative support through informational web sites, call centers, patient support groups, and<br />
special fidelity programs.<br />
� Pharmacist<br />
� Consider point of sales as an ally, an important part of the commercialization cycle in which they<br />
interact with the patients who buy our products.<br />
8
Clients<br />
� Excellent client relationships guarantee<br />
profitable long term business agreements.<br />
� In Chile, Andromaco is the primary supplier of<br />
medicines to CENABAST, the largest buyer and<br />
distributor of Chile’s public health institutions<br />
(hospitals).<br />
� Sales in the hospital and public health sector<br />
has grown to be 44% of corporate sales in<br />
units. Sales in this area grew 7%.<br />
� <strong>Empresas</strong> <strong>Andrómaco</strong> provides fast and<br />
efficient online services for its customers as<br />
well as EDI services (electronic orders).<br />
� The Company’s effective distribution network<br />
provides rapid access to health products in<br />
every major city of each country where we do<br />
business.<br />
Corporate Pharma Sales 2009<br />
(dollars)<br />
Pharmacy<br />
Chains<br />
49%<br />
Hospitals/<br />
Public Inst.<br />
26%<br />
Retail<br />
1%<br />
Wholesaler<br />
17%<br />
Independent<br />
Pharmacies<br />
7%<br />
9
Research, Development & Outlicensing<br />
� The Company actively participates in crucial basic research for therapeutic innovations in a wide variety<br />
of medical specialties.<br />
� Currently, the Company has established important strategic alliances with the following universities and<br />
other prestigious national and international institutions:<br />
� Population Council and The Rockefeller Foundation<br />
� The Conrad Foundation<br />
� University of Sao Paulo, Brazil<br />
� University of La Frontera, Chile<br />
� University of Concepción, Chile<br />
� Chilean Institute of Reproductive Medicine (ICMER)<br />
� Products developed, marketed and outlicensed<br />
� Progering: innovative contraceptive vaginal ring for breastfeeding<br />
� Fertiring: provides timed release hormone supplementation for<br />
women without normal progesterone secretion for in‐vitro<br />
fertilization procedures<br />
� Actiser T: testosterone replacement therapy<br />
10
Facilities<br />
� Manufacturing Facilities. Santiago, Chile.<br />
� Ground : 25.740 m2<br />
� Offices : 3.250 m2<br />
� Quality Control : 120 m2<br />
� Workshop : 250 m2<br />
� Production Plants:<br />
� Hormonal Plant : 610 m2<br />
� Non Hormonal Plant : 1.130 m2<br />
� Liquids Plant : 1.940 m2<br />
� Warehouse : 2.440 m2<br />
� Production Capacity (annual, 3 shifts per day)<br />
� Non Hormonal Tablets/Capsules : 204.400.000 units<br />
� Hormonal Tablets/Capsules : 20.400.000 units<br />
� Liquids : 28.300.000 units<br />
11
Organizational Chart<br />
Perú<br />
Bolivia<br />
Ecuador<br />
Colombia<br />
Panamá<br />
Costa Rica<br />
El Salvador<br />
Guatemala<br />
R. Dominicana<br />
Fernando<br />
Muñoz<br />
12
Market Arena<br />
� Headquartered in Chile, the Company serves<br />
Latin America through commercial<br />
subsidiaries in Peru, Bolivia, Ecuador,<br />
Colombia, Costa Rica, Panama, El Salvador,<br />
Guatemala, Dominican Republic as well as its<br />
network of distributors in Paraguay, Uruguay<br />
and other Central American nations.<br />
� <strong>Empresas</strong> <strong>Andrómaco</strong> employs more than<br />
1,200 professionals in manufacturing, sales,<br />
promotion and distribution operations.<br />
� To meet unique regional and customer needs<br />
<strong>Andrómaco</strong> produces and imports in excess of<br />
500 products, marketed in over 1,300 distinct<br />
formulations in private and public markets.<br />
� Production facilities are located in Santiago,<br />
Chile.<br />
Guatemala<br />
El Salvador<br />
Costa Rica<br />
Ecuador<br />
Medical Sales Reps<br />
Bolivia 30<br />
Chile 250<br />
Colombia 40<br />
Costa Rica 10<br />
Ecuador 80<br />
El Salvador 10<br />
Guatemala 15<br />
Panamá 20<br />
Peru 135<br />
R. Dominicana 25<br />
TOTAL 615<br />
Panamá<br />
Perú<br />
Chile<br />
Haití<br />
República Dominicana<br />
Colombia<br />
Bolivia<br />
Paraguay<br />
Uruguay<br />
13
IMS Private Markets<br />
PAIS (+000) 2008 2009 +/-08/09 2008 2009 +/-08/09 2009<br />
UN-T.UNITS UN-T.UNITS VAR. UN US-T.USD US-T.USD VAR. US PRECIO PROM<br />
TOTAL 945,293 965,407 2.13 5,723,517 5,584,412 -2.43<br />
5.78<br />
COLOMBIA 291,694 298,199 2.23 1,747,959 1,540,127 -11.89<br />
5.16<br />
CHILE 224,637 223,671 -0.43 1,069,543 978,418 -8.52<br />
4.37<br />
ECUADOR 159,286 171,242 7.51 749,390 835,722 11.52<br />
4.88<br />
PERU 98,467 96,385 -2.11 701,461 680,383 -3.00<br />
7.06<br />
DOMINICANA 38,339 38,795 1.19 368,739 395,050 7.14<br />
10.18<br />
GUATEMALA 42,335 41,706 -1.48 347,275 343,342 -1.13<br />
8.23<br />
COSTA RICA 22,751 23,058 1.35 242,208 257,912 6.48<br />
11.19<br />
EL SALVADOR 22,188 21,136 -4.74 194,678 188,889 -2.97<br />
8.94<br />
PANAMA 22,382 23,428 4.67 171,890 186,625 8.57<br />
7.97<br />
BOLIVIA 23,215 27,788 19.70 130,375 177,945 36.49<br />
6.40<br />
* mat ago 2009<br />
7%<br />
5%<br />
6%<br />
12%<br />
3%<br />
3%<br />
3%<br />
15%<br />
28%<br />
18%<br />
COLOMBIA<br />
CHILE<br />
ECUADOR<br />
PERU<br />
DOMINICANA<br />
GUATEMALA<br />
COSTA RICA<br />
EL SALVADOR<br />
PANAMA<br />
14
TOTAL BOLIVIA COLOMBIA COSTA RICA CHILE ECUADOR EL SALVADOR GUATEMALA PANAMÁ PERÚ R. DOMINICANA<br />
Población (est. Jul 2009) 153,887,180 9,775,246 45,664,023 4,253,877 16,601,707 14,573,101 7,185,218 13,276,517 3,360,474 29,546,963 9,650,054<br />
Gasto US$/persona anual 36.3 18.2 33.7 60.6 58.9 57.3 26.3 25.9 55.5 23.0 40.9<br />
USD '000 TOTAL BOLIVIA COLOMBIA COSTA RICA CHILE ECUADOR EL SALVADOR GUATEMALA PANAMÁ PERÚ R. DOMINICANA<br />
TOTAL US$ 5,584,412 177,945 1,540,127 257,912 978,418 835,722 188,889 343,342 186,625 680,383 395,050<br />
Precio Promedio 5.78 6.40 5.16 11.19 4.37 4.88 8.94 8.23 7.97 7.06 10.18<br />
% Crecimiento ‐2.43% 36.49% ‐11.89% 6.48% ‐8.52% 11.52% ‐2.97% ‐1.13% 8.57% ‐3.00% 7.14%<br />
% Peso 100.00% 3.19% 27.58% 4.62% 17.52% 14.97% 3.38% 6.15% 3.34% 12.18% 7.07%<br />
TOTAL UN 965,407 27,788 298,199 23,058 223,671 171,242 21,136 41,706 23,428 96,385 38,795<br />
% Crecimiento 2.13% 19.70% 2.23% 1.35% ‐0.43% 7.51% ‐4.74% ‐1.48% 4.67% ‐2.11% 1.19%<br />
ETICO US$ 5,179,595 165,247 1,375,419 239,896 918,343 784,660 173,039 326,313 175,167 646,116 375,395<br />
% Crecimiento 6.76% 37.40% 8.97% 4.80% ‐8.69% 20.66% ‐2.10% 3.49% 13.31% 8.94% 8.98%<br />
GENERICO US$ 404,817 12,698 164,708 18,016 60,075 51,062 15,850 17,029 11,459 34,267 19,655<br />
% Crecimiento ‐5.18% 37.38% ‐14.11% 3.94% ‐5.73% 10.43% ‐1.60% ‐2.48% 7.97% ‐5.06% 7.09%<br />
EMPRESAS ANDROMACO 90,519 2,687 260 1,532 63,695 4,683 309 1,119 2,571 13,585 78<br />
Precio Promedio 6.67 9.38 15.93 9.33 6.14 5.71 12.98 7.44 12.13 9.02 9.57<br />
% Crec US$ 0.52% 32.77% ‐26.08% 18.16% ‐2.43% 17.15% 72.00% 31.39% 41.95% ‐4.30% 26.94%<br />
I Evol US$ 103 97 84 111 107 105 177 133 131 99 118<br />
% MS US$ 1.62% 1.51% 0.02% 0.59% 6.51% 0.56% 0.16% 0.33% 1.38% 2.00% 0.02%<br />
*MAT Agosto 2009<br />
IMS Private Markets<br />
15
Our Companies<br />
Corporate Sales by Subsidiary 2009<br />
(dollars)<br />
<strong>Andrómaco</strong><br />
66%<br />
www.empresasandromaco.cl<br />
Mastercare<br />
1%<br />
Silesia<br />
15%<br />
Diagnotec<br />
1%<br />
ABL<br />
17%<br />
16
LABORATORIOS ANDRÓMACO S.A.<br />
� <strong>Andrómaco</strong> Laboratories initiated operations in Chile in 1942 and already in the first market evaluations<br />
carried out in 1977, the company began to appear among the ten more important companies of the<br />
sector .<br />
� Since 1980 it has been continuously positioned among the first five laboratories of the Chilean<br />
pharmaceutical market and today is a leading company in the ethical products marketing.<br />
� In addition to the prescription market, it has a supply of high technology and generic products, and<br />
participates strongly in the OTC and institutional markets.<br />
17
ABL Pharma<br />
� It is the trade mark by which the <strong>Andrómaco</strong><br />
Companies operate in the foreign market,<br />
bringing, mainly own and licensed ethical<br />
products to the regional markets.<br />
� It is composed by<br />
� ABL Pharma Bolivia, 1993<br />
� ABL Pharma Peru, 1995<br />
� ABL Pharma Ecuador, 2002<br />
� ABL Pharma Costa Rica, 2004<br />
� ABL Pharma Panama, 2004<br />
� ABL Pharma Colombia, 2005<br />
� ABL Pharma El Salvador, 2006<br />
� ABL Pharma R. Dominicana, 2007<br />
� ABL Pharma Guatemala, 2007<br />
ABL Pharma Sales 2009<br />
(dollars in thousands)<br />
Perú<br />
56%<br />
Bolivia<br />
7%<br />
Ecuador<br />
17%<br />
Colombia<br />
2%<br />
Central Am<br />
18%<br />
18
LABORATORIOS SILESIA S.A.<br />
� With more than 50 years in the market, Silesia is a laboratory of specialties with medical prescription<br />
products for women of high quality and recognition in the medical field, within which there is an ample<br />
hormonal products range, specially its contraceptives and hormonal replacement therapy products.<br />
� Incorporated in the year 2005 to the <strong>Andrómaco</strong> Group of Companies, today is fundamentally oriented<br />
to women's health and quality of life with products highly present in the areas of Gynecology,<br />
Neurospsychiatry and Dermatology, among others.<br />
� Its portfolio includes an important number of licensed products.<br />
19
MASTERCARE<br />
� MasterCare markets and commercializes novel healthcare solutions specially developed to be used in<br />
hospitals and clinics. The products and services address prevention, diagnosis and treatment of<br />
diseases.<br />
� Arranged in three operative divisions, our global mission is to create exceptional added value in<br />
healthcare. These three units are:<br />
� Pharmaceutical<br />
� Specialized Medical Disposable Devices<br />
� Diagnostics<br />
� Team<br />
� Commercial oriented<br />
� Very well trained<br />
� Experienced<br />
� Immediate access to health authorities<br />
� Solid public tender expertise<br />
20
FERRER ANDROMACO<br />
� It is a joint‐venture company with Ferrer Spain created in 2004, that reflects the company decision to<br />
search for different commercial association structures to accede to state‐of‐art products. Ferrer‐<br />
<strong>Andrómaco</strong> supplies highly sophisticated technological products, to be used for diseases require<br />
therapies of high specificity.<br />
� This association expresses the confidence the Andromaco Companies arises in international companies.<br />
Ferrer is one of the most important Spanish conglomerates with a high participation in the European<br />
Community pharmaceutical market.<br />
DIAGNOTEC<br />
� Diagnotec is leader in the domestic market and a pioneer in the induction of molecular diagnostics<br />
industries in aquaculture, swine and food.<br />
� Diagnotec develops ictiopatologic services, molecular diagnostic, genetic integrated management<br />
programs and biological evaluation<br />
� Diagnotec, developed the first antiviral treatment for control of IPNv, the highest incidence of the virus<br />
in farmed salmon in the world. The company has already conducted trials of these compounds in<br />
antiviral ground for its next launch in the country and is under patent in Europe (including Norway),<br />
U.S., Canada and Chile.<br />
21
Investor Relations<br />
Andrés Rudolphy, CEO<br />
Juan I. Sandoval, CFO<br />
juan.sandoval@andromaco.cl<br />
+56 2 594 84 17<br />
22