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<strong>Empresas</strong> <strong>Andrómaco</strong> Andr <strong>Andrómaco</strong> maco <strong>Overview</strong><br />

March 22nd March 22 , 2010 nd , 2010<br />

1


Corporate Profile<br />

� <strong>Empresas</strong> <strong>Andrómaco</strong> is one of the leading pharmaceutical companies along the Pacific Coast of Latin<br />

America, with strong manufacturing, marketing and distribution networks for medicines, nutritional<br />

products and medical supplies.<br />

� The Company positions itself as a Pharmaceutical Marketing Company, specialized in Prescription and<br />

specialized healthcare products, for private an public markets, recognized by the quality and efficiency<br />

of commercial management.<br />

� The Company has a strong capacity to create high demand in private and institutional markets, based<br />

on experience, quality, and extensive outreach to medical professionals.<br />

� Sales force of over 600 professionals<br />

� The Company provides effective and efficient marketing channels including promotion throughout the<br />

health care industry, among consumers, through trade organizations and existing sales and distribution<br />

networks.<br />

� <strong>Empresas</strong> <strong>Andrómaco</strong> is the best strategic partner for international companies interested in developing<br />

their pharmaceutical business in Latin America.<br />

2


History<br />

1927 � Laboratorios <strong>Andrómaco</strong> was founded in Spain<br />

1942 � <strong>Andrómaco</strong> launches operations in Chile<br />

1979 � <strong>Andrómaco</strong> separates from Spanish parent company and merges with Chilean laboratories<br />

1993 � First branch ABL Pharma Bolivia is opened<br />

2002 � <strong>Andrómaco</strong> achieves GMP certification from the Public Health Institute (ISP) of Chile<br />

2002 � New strategic approach EMPRESAS ANDROMACO<br />

2004 � <strong>Andrómaco</strong> initiates share offering on Chilean stock market<br />

2004 � The Ferrer‐Andromaco joint‐venture is inaugurated<br />

2005 � <strong>Empresas</strong> <strong>Andrómaco</strong> buys Laboratorio Silesia<br />

2005 � <strong>Andrómaco</strong> laboratories receives its second GMP certification from the ISP of Chile<br />

2005 � <strong>Empresas</strong> <strong>Andrómaco</strong> achieves CENABAST certification<br />

2006 � <strong>Andrómaco</strong> Laboratories receives INVIMA certification for all production lines<br />

2006 � <strong>Andrómaco</strong> is ranked as number two laboratory in Chile in units<br />

2007 � ABL Pharma Dominican Republic begins operations<br />

2007 � <strong>Andrómaco</strong> buys IPROFASA in Guatemala<br />

2007 � MasterCare is founded<br />

2008 � 80% of Diagnotec is acquired<br />

2008 � <strong>Andrómaco</strong> opens the first Biofarmaceutical Center to be approved in Chile<br />

2009 � Number 1 supplier public sector<br />

3


Property Structure<br />

� Open joint‐stock company marketed in the<br />

Commerce Stock Exchange of Santiago.<br />

� Risk classification<br />

� Feller Rate: first Class, Level 3<br />

� Fitch Chile: first Class, Level 3<br />

Sahrehoders Shares %<br />

INVERSIONES NM LIMITADA 196,189,121 35.0%<br />

MONEDA SA AFI PARA PIONERO FONDO DE INVERSION 80,679,000 14.4%<br />

FONDO DE INVERSION LARRAIN VIAL BEAGLE 37,301,079 6.7%<br />

CELFIN SMALL CAP CHILE FONDO DE INVERSIO 33,588,822 6.0%<br />

MONEDA SA AFI PARA COLONO FONDO DE INVERSION 33,357,000 6.0%<br />

COMPASS EMERGENTE FONDO DE INVERSION 28,655,760 5.1%<br />

CELFIN CAPITAL S A C DE B 25,293,664 4.5%<br />

CHILE FONDO DE INVERSION SMALL CAP 19,960,453 3.6%<br />

INVERSIONES MARDOS SA 15,000,000 2.7%<br />

SIGLO XXI FONDO DE INVERSION 9,542,950 1.7%<br />

MONEDA SA AFI PARA MONEDA CHILE FUND LTD 8,928,000 1.6%<br />

LARRAIN VIAL S A CORREDORA DE BOLSA 7,204,024 1.3%<br />

Sub Total 495,699,873 88.43%<br />

Other 64,840,673 11.57%<br />

Total 560,540,546 100.00%<br />

Corporate Ownership<br />

US$/share<br />

0.40<br />

0.35<br />

0.30<br />

0.25<br />

0.20<br />

0.15<br />

0.10<br />

0.05<br />

sep‐04<br />

NM Private<br />

Investor<br />

35%<br />

Other Share‐<br />

holders<br />

24%<br />

ene‐05<br />

0.2<br />

may‐05<br />

0.2<br />

sep‐05<br />

ene‐06<br />

0.23<br />

may‐06<br />

sep‐06<br />

ene‐07<br />

0.38 0.37<br />

may‐07<br />

sep‐07<br />

ene‐08<br />

Moneda<br />

Investment<br />

Funds<br />

22%<br />

Celfin<br />

Investment<br />

Funds<br />

11%<br />

Larrain Vial<br />

Inv. Funds<br />

8%<br />

0.29<br />

may‐08<br />

sep‐08<br />

0.16<br />

ene‐09<br />

0.29<br />

may‐09<br />

sep‐09<br />

4<br />

0.32<br />

ene‐10<br />

CLP/USD = 510


Financial Highlights<br />

Corporate Sales<br />

(dollars in thousands)<br />

$ 103,400<br />

$ 133,100<br />

$ 146,200 $ 162,200 $ 172,900 $ 172,800<br />

2004 2005 2006 2007 2008 2009<br />

EBITDA<br />

(dollars in thousands)<br />

$ 15,000<br />

$ 20,600<br />

$ 21,700<br />

$ 23,400 $ 23,500<br />

$ 31,500<br />

2004 2005 2006 2007 2008 2009<br />

Net Income<br />

(dollars in thousands)<br />

$ 7,900<br />

$ 8,500<br />

$ 11,600<br />

$ 10,900<br />

$ 5,200<br />

$ 16,400<br />

2004 2005 2006 2007 2008 2009<br />

Operating Profit<br />

(dollars in thousands)<br />

$ 11,100<br />

$ 15,400<br />

Non operational<br />

loss mainly due to<br />

exchange rate and<br />

organizational<br />

restructure<br />

$ 18,500 $ 19,700 $ 18,800<br />

$ 25,600<br />

2004 2005 2006 2007 2008 2009<br />

CLP/USD = 510<br />

5


Product Divisions<br />

Rx Marketing Division<br />

� Represents 45% of total sales.<br />

� Subsidiaries (Silesia, MasterCare, ABL Pharma)<br />

are focused primarily in prescription<br />

medications.<br />

� Cardiology, Neuropsychiatry, Genecology,<br />

Dermatology, Pediatrics and Hospital drugs<br />

represent some of our primary strategic<br />

therapeutic areas.<br />

OTC‐UTC Division<br />

� Represents 23% of Chilean national sales and<br />

19% of corporate sales.<br />

� 2nd leading OTC provider in Chile.<br />

� Solid competency in direct‐to‐consumer and<br />

trade marketing.<br />

Generics Division<br />

� 25% of total Chilean national sales.<br />

� More than 180 presentations.<br />

� 2nd leading generics provider in Chile.<br />

Chile Pharma Sales by Product Division<br />

(dollars in millions)<br />

$ 33<br />

$ 37<br />

$ 34<br />

$ 69<br />

$ 68<br />

$ 67<br />

$ 30<br />

$ 34<br />

$ 37<br />

Generic Rx UTC+OTC Clinic<br />

Products<br />

� Strong recognition, satisfaction and<br />

acceptance among doctors and patients.<br />

� Products manufactured through total quality<br />

and GMP industrial methodologies certified by<br />

Chile and Colombia.<br />

� In addition to its own highly regarded<br />

proprietary products, <strong>Andrómaco</strong> provides a<br />

wide range of recognized and prominent<br />

licensed products.<br />

$ 1<br />

2007<br />

2008<br />

2009<br />

$ 2<br />

6


Licenses and Strategic Alliances<br />

Corporate Pharma Sales 2009<br />

(dollars)<br />

Generic<br />

Prods<br />

20%<br />

OTC+UTC<br />

Prods<br />

22%<br />

Licensed<br />

Prescription<br />

Prods<br />

16%<br />

Propietary<br />

Prescription<br />

Prods<br />

42%<br />

� <strong>Empresas</strong> <strong>Andrómaco</strong>’s partners have ready<br />

access to comprehensive and efficient<br />

marketing to medical professionals throughout<br />

the region.<br />

� The Company has received licenses from over<br />

50 leading pharmaceutical companies for the<br />

Central and South American market for more<br />

than 125 products.<br />

� Argentina: Gador, Phoenix, Andromaco Argentina<br />

� Austria: Reisenberger GmbH<br />

� Canada: Pharmascience<br />

� Chile: Biosano<br />

� Costa Rica: Newport<br />

� Denmark: Lundbeck, Novonordisk, Nycomed, Leo, Statem<br />

Serum<br />

� France: Pierre Fabre Dermocosmetic, Pierre Fabre<br />

Medicament, Fournier<br />

� Germany: Sankyo, Schwabbe, Grünenthal, Fujisawa, AMG Int.<br />

� India: Cipla, Claris, Dr. Reddys, Gland Pharma, Ind‐Swit Ltd,<br />

Pure, Ranbaxy<br />

� Italy: Alfawasserwan, Boehringer Ingelheim Italy, Chiesi,<br />

Foltene, Recordati, Rottapharm, SPA<br />

� Japan: Hisamitsu, Taisho, Mitsubishi<br />

� Mexico: Aplicaciones Farmacéuticas<br />

� Neatherlands: Nutricia<br />

� Spain: Bioibérica, Eurogine, Ferrer, Isdin, Lab. Esteve, Lab.<br />

Viñas, Phivor, Robert, Uriach<br />

� Switzerland: Helsinn, Om, TRB Chemedica, Vifor<br />

� United States: Mallinkrodt, Host Pharma,Gen Probe,Three<br />

Rivers Pharmaceuticals<br />

7


Commercial Approach<br />

� Physician<br />

� Provide clinical and therapeutic research information to doctors allowing them access to updated<br />

pharmaceutical knowledge.<br />

� One on one marketing according to their profile and prescription preferences.<br />

� Institutional Clinical MD and personnel<br />

� Patient<br />

� Create exceptional added value with novel healthcare solutions for institutional markets.<br />

� Offer a broad range of high quality products and commit to excellence in service<br />

� Understand our product consumers, go ahead of their needs and provide informative and<br />

educative support through informational web sites, call centers, patient support groups, and<br />

special fidelity programs.<br />

� Pharmacist<br />

� Consider point of sales as an ally, an important part of the commercialization cycle in which they<br />

interact with the patients who buy our products.<br />

8


Clients<br />

� Excellent client relationships guarantee<br />

profitable long term business agreements.<br />

� In Chile, Andromaco is the primary supplier of<br />

medicines to CENABAST, the largest buyer and<br />

distributor of Chile’s public health institutions<br />

(hospitals).<br />

� Sales in the hospital and public health sector<br />

has grown to be 44% of corporate sales in<br />

units. Sales in this area grew 7%.<br />

� <strong>Empresas</strong> <strong>Andrómaco</strong> provides fast and<br />

efficient online services for its customers as<br />

well as EDI services (electronic orders).<br />

� The Company’s effective distribution network<br />

provides rapid access to health products in<br />

every major city of each country where we do<br />

business.<br />

Corporate Pharma Sales 2009<br />

(dollars)<br />

Pharmacy<br />

Chains<br />

49%<br />

Hospitals/<br />

Public Inst.<br />

26%<br />

Retail<br />

1%<br />

Wholesaler<br />

17%<br />

Independent<br />

Pharmacies<br />

7%<br />

9


Research, Development & Outlicensing<br />

� The Company actively participates in crucial basic research for therapeutic innovations in a wide variety<br />

of medical specialties.<br />

� Currently, the Company has established important strategic alliances with the following universities and<br />

other prestigious national and international institutions:<br />

� Population Council and The Rockefeller Foundation<br />

� The Conrad Foundation<br />

� University of Sao Paulo, Brazil<br />

� University of La Frontera, Chile<br />

� University of Concepción, Chile<br />

� Chilean Institute of Reproductive Medicine (ICMER)<br />

� Products developed, marketed and outlicensed<br />

� Progering: innovative contraceptive vaginal ring for breastfeeding<br />

� Fertiring: provides timed release hormone supplementation for<br />

women without normal progesterone secretion for in‐vitro<br />

fertilization procedures<br />

� Actiser T: testosterone replacement therapy<br />

10


Facilities<br />

� Manufacturing Facilities. Santiago, Chile.<br />

� Ground : 25.740 m2<br />

� Offices : 3.250 m2<br />

� Quality Control : 120 m2<br />

� Workshop : 250 m2<br />

� Production Plants:<br />

� Hormonal Plant : 610 m2<br />

� Non Hormonal Plant : 1.130 m2<br />

� Liquids Plant : 1.940 m2<br />

� Warehouse : 2.440 m2<br />

� Production Capacity (annual, 3 shifts per day)<br />

� Non Hormonal Tablets/Capsules : 204.400.000 units<br />

� Hormonal Tablets/Capsules : 20.400.000 units<br />

� Liquids : 28.300.000 units<br />

11


Organizational Chart<br />

Perú<br />

Bolivia<br />

Ecuador<br />

Colombia<br />

Panamá<br />

Costa Rica<br />

El Salvador<br />

Guatemala<br />

R. Dominicana<br />

Fernando<br />

Muñoz<br />

12


Market Arena<br />

� Headquartered in Chile, the Company serves<br />

Latin America through commercial<br />

subsidiaries in Peru, Bolivia, Ecuador,<br />

Colombia, Costa Rica, Panama, El Salvador,<br />

Guatemala, Dominican Republic as well as its<br />

network of distributors in Paraguay, Uruguay<br />

and other Central American nations.<br />

� <strong>Empresas</strong> <strong>Andrómaco</strong> employs more than<br />

1,200 professionals in manufacturing, sales,<br />

promotion and distribution operations.<br />

� To meet unique regional and customer needs<br />

<strong>Andrómaco</strong> produces and imports in excess of<br />

500 products, marketed in over 1,300 distinct<br />

formulations in private and public markets.<br />

� Production facilities are located in Santiago,<br />

Chile.<br />

Guatemala<br />

El Salvador<br />

Costa Rica<br />

Ecuador<br />

Medical Sales Reps<br />

Bolivia 30<br />

Chile 250<br />

Colombia 40<br />

Costa Rica 10<br />

Ecuador 80<br />

El Salvador 10<br />

Guatemala 15<br />

Panamá 20<br />

Peru 135<br />

R. Dominicana 25<br />

TOTAL 615<br />

Panamá<br />

Perú<br />

Chile<br />

Haití<br />

República Dominicana<br />

Colombia<br />

Bolivia<br />

Paraguay<br />

Uruguay<br />

13


IMS Private Markets<br />

PAIS (+000) 2008 2009 +/-08/09 2008 2009 +/-08/09 2009<br />

UN-T.UNITS UN-T.UNITS VAR. UN US-T.USD US-T.USD VAR. US PRECIO PROM<br />

TOTAL 945,293 965,407 2.13 5,723,517 5,584,412 -2.43<br />

5.78<br />

COLOMBIA 291,694 298,199 2.23 1,747,959 1,540,127 -11.89<br />

5.16<br />

CHILE 224,637 223,671 -0.43 1,069,543 978,418 -8.52<br />

4.37<br />

ECUADOR 159,286 171,242 7.51 749,390 835,722 11.52<br />

4.88<br />

PERU 98,467 96,385 -2.11 701,461 680,383 -3.00<br />

7.06<br />

DOMINICANA 38,339 38,795 1.19 368,739 395,050 7.14<br />

10.18<br />

GUATEMALA 42,335 41,706 -1.48 347,275 343,342 -1.13<br />

8.23<br />

COSTA RICA 22,751 23,058 1.35 242,208 257,912 6.48<br />

11.19<br />

EL SALVADOR 22,188 21,136 -4.74 194,678 188,889 -2.97<br />

8.94<br />

PANAMA 22,382 23,428 4.67 171,890 186,625 8.57<br />

7.97<br />

BOLIVIA 23,215 27,788 19.70 130,375 177,945 36.49<br />

6.40<br />

* mat ago 2009<br />

7%<br />

5%<br />

6%<br />

12%<br />

3%<br />

3%<br />

3%<br />

15%<br />

28%<br />

18%<br />

COLOMBIA<br />

CHILE<br />

ECUADOR<br />

PERU<br />

DOMINICANA<br />

GUATEMALA<br />

COSTA RICA<br />

EL SALVADOR<br />

PANAMA<br />

14


TOTAL BOLIVIA COLOMBIA COSTA RICA CHILE ECUADOR EL SALVADOR GUATEMALA PANAMÁ PERÚ R. DOMINICANA<br />

Población (est. Jul 2009) 153,887,180 9,775,246 45,664,023 4,253,877 16,601,707 14,573,101 7,185,218 13,276,517 3,360,474 29,546,963 9,650,054<br />

Gasto US$/persona anual 36.3 18.2 33.7 60.6 58.9 57.3 26.3 25.9 55.5 23.0 40.9<br />

USD '000 TOTAL BOLIVIA COLOMBIA COSTA RICA CHILE ECUADOR EL SALVADOR GUATEMALA PANAMÁ PERÚ R. DOMINICANA<br />

TOTAL US$ 5,584,412 177,945 1,540,127 257,912 978,418 835,722 188,889 343,342 186,625 680,383 395,050<br />

Precio Promedio 5.78 6.40 5.16 11.19 4.37 4.88 8.94 8.23 7.97 7.06 10.18<br />

% Crecimiento ‐2.43% 36.49% ‐11.89% 6.48% ‐8.52% 11.52% ‐2.97% ‐1.13% 8.57% ‐3.00% 7.14%<br />

% Peso 100.00% 3.19% 27.58% 4.62% 17.52% 14.97% 3.38% 6.15% 3.34% 12.18% 7.07%<br />

TOTAL UN 965,407 27,788 298,199 23,058 223,671 171,242 21,136 41,706 23,428 96,385 38,795<br />

% Crecimiento 2.13% 19.70% 2.23% 1.35% ‐0.43% 7.51% ‐4.74% ‐1.48% 4.67% ‐2.11% 1.19%<br />

ETICO US$ 5,179,595 165,247 1,375,419 239,896 918,343 784,660 173,039 326,313 175,167 646,116 375,395<br />

% Crecimiento 6.76% 37.40% 8.97% 4.80% ‐8.69% 20.66% ‐2.10% 3.49% 13.31% 8.94% 8.98%<br />

GENERICO US$ 404,817 12,698 164,708 18,016 60,075 51,062 15,850 17,029 11,459 34,267 19,655<br />

% Crecimiento ‐5.18% 37.38% ‐14.11% 3.94% ‐5.73% 10.43% ‐1.60% ‐2.48% 7.97% ‐5.06% 7.09%<br />

EMPRESAS ANDROMACO 90,519 2,687 260 1,532 63,695 4,683 309 1,119 2,571 13,585 78<br />

Precio Promedio 6.67 9.38 15.93 9.33 6.14 5.71 12.98 7.44 12.13 9.02 9.57<br />

% Crec US$ 0.52% 32.77% ‐26.08% 18.16% ‐2.43% 17.15% 72.00% 31.39% 41.95% ‐4.30% 26.94%<br />

I Evol US$ 103 97 84 111 107 105 177 133 131 99 118<br />

% MS US$ 1.62% 1.51% 0.02% 0.59% 6.51% 0.56% 0.16% 0.33% 1.38% 2.00% 0.02%<br />

*MAT Agosto 2009<br />

IMS Private Markets<br />

15


Our Companies<br />

Corporate Sales by Subsidiary 2009<br />

(dollars)<br />

<strong>Andrómaco</strong><br />

66%<br />

www.empresasandromaco.cl<br />

Mastercare<br />

1%<br />

Silesia<br />

15%<br />

Diagnotec<br />

1%<br />

ABL<br />

17%<br />

16


LABORATORIOS ANDRÓMACO S.A.<br />

� <strong>Andrómaco</strong> Laboratories initiated operations in Chile in 1942 and already in the first market evaluations<br />

carried out in 1977, the company began to appear among the ten more important companies of the<br />

sector .<br />

� Since 1980 it has been continuously positioned among the first five laboratories of the Chilean<br />

pharmaceutical market and today is a leading company in the ethical products marketing.<br />

� In addition to the prescription market, it has a supply of high technology and generic products, and<br />

participates strongly in the OTC and institutional markets.<br />

17


ABL Pharma<br />

� It is the trade mark by which the <strong>Andrómaco</strong><br />

Companies operate in the foreign market,<br />

bringing, mainly own and licensed ethical<br />

products to the regional markets.<br />

� It is composed by<br />

� ABL Pharma Bolivia, 1993<br />

� ABL Pharma Peru, 1995<br />

� ABL Pharma Ecuador, 2002<br />

� ABL Pharma Costa Rica, 2004<br />

� ABL Pharma Panama, 2004<br />

� ABL Pharma Colombia, 2005<br />

� ABL Pharma El Salvador, 2006<br />

� ABL Pharma R. Dominicana, 2007<br />

� ABL Pharma Guatemala, 2007<br />

ABL Pharma Sales 2009<br />

(dollars in thousands)<br />

Perú<br />

56%<br />

Bolivia<br />

7%<br />

Ecuador<br />

17%<br />

Colombia<br />

2%<br />

Central Am<br />

18%<br />

18


LABORATORIOS SILESIA S.A.<br />

� With more than 50 years in the market, Silesia is a laboratory of specialties with medical prescription<br />

products for women of high quality and recognition in the medical field, within which there is an ample<br />

hormonal products range, specially its contraceptives and hormonal replacement therapy products.<br />

� Incorporated in the year 2005 to the <strong>Andrómaco</strong> Group of Companies, today is fundamentally oriented<br />

to women's health and quality of life with products highly present in the areas of Gynecology,<br />

Neurospsychiatry and Dermatology, among others.<br />

� Its portfolio includes an important number of licensed products.<br />

19


MASTERCARE<br />

� MasterCare markets and commercializes novel healthcare solutions specially developed to be used in<br />

hospitals and clinics. The products and services address prevention, diagnosis and treatment of<br />

diseases.<br />

� Arranged in three operative divisions, our global mission is to create exceptional added value in<br />

healthcare. These three units are:<br />

� Pharmaceutical<br />

� Specialized Medical Disposable Devices<br />

� Diagnostics<br />

� Team<br />

� Commercial oriented<br />

� Very well trained<br />

� Experienced<br />

� Immediate access to health authorities<br />

� Solid public tender expertise<br />

20


FERRER ANDROMACO<br />

� It is a joint‐venture company with Ferrer Spain created in 2004, that reflects the company decision to<br />

search for different commercial association structures to accede to state‐of‐art products. Ferrer‐<br />

<strong>Andrómaco</strong> supplies highly sophisticated technological products, to be used for diseases require<br />

therapies of high specificity.<br />

� This association expresses the confidence the Andromaco Companies arises in international companies.<br />

Ferrer is one of the most important Spanish conglomerates with a high participation in the European<br />

Community pharmaceutical market.<br />

DIAGNOTEC<br />

� Diagnotec is leader in the domestic market and a pioneer in the induction of molecular diagnostics<br />

industries in aquaculture, swine and food.<br />

� Diagnotec develops ictiopatologic services, molecular diagnostic, genetic integrated management<br />

programs and biological evaluation<br />

� Diagnotec, developed the first antiviral treatment for control of IPNv, the highest incidence of the virus<br />

in farmed salmon in the world. The company has already conducted trials of these compounds in<br />

antiviral ground for its next launch in the country and is under patent in Europe (including Norway),<br />

U.S., Canada and Chile.<br />

21


Investor Relations<br />

Andrés Rudolphy, CEO<br />

Juan I. Sandoval, CFO<br />

juan.sandoval@andromaco.cl<br />

+56 2 594 84 17<br />

22

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