Marie Curie Fellow - faculty.jacobs-university.de - Jacobs University

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Name: Institute: Université de la Méditerranée Microbiology Aix-en-Marseille UMR-MD 1 Enveloppe bacterienne, perméabilité et antibiotique Maseille, France Chloe.James@medecine.univ-mrs.fr Expertise: Postdoc specialising in Molecular Microbiology Short CV: Dr. Chloé Elizabeth James 2003-2006: Post Doctoral Researcher at the University of Florida, Dept of Oral Biology: employed by Prof Richard Lamont. Funded by The National Institute of Health (NIH) Project: Investigation of the pathophysiology of the oral pathogens. I used molecular techniques (genetic manipulation, real-time PCR, microarray analysis and protein purification) to study gene expression effected by cell-cell signalling and interactions between P. gingivalis and S. gordonii. 2001-2002: Post Doctoral Researcher at the University of Liverpool, School of Biol Sci: employed by Prof. Alan McCarthy. Funded by The Biotechnology and Biological Science Research Council (BBSRC). Project: Molecular characterisation of verotoxigenic bacteriophage infection. I used molecular techniques to investigate bacteriophage immunity and a host receptor protein for the bacteriophage attachment and infection. 1998 - 2001: PhD Studentship at the University of Liverpool, School Biological Sciences: Supervisors: Profs J.R. Saunders, A.J. McCarthy and R. Sharp. Funded by The Ministry of Agriculture Fisheries and Food (MAFF) / Centre for Applied Microbiological Research (CAMR). Title: “Use of a Recombinant Verocytotoxigenic Phage to Investigate Infection of Bacterial Hosts” Your responsibility in the network: Post Doctoral Researcher July 2006- July 2008 Employed by Prof Jean-Marie Pages Project: Investigation of the transport of antibiotics across the outer membrane of multi-drug resistant Gram negative bacteria. Use of molecular techniques including genetic manipulation and protein purification to investigate the role of outer membrane porins of E. coli and E. aerogenes and their regulation. Your experience (positive/negative) with our network up to now: I have enjoyed working on a very interesting project that has taught me new techniques and introduced me to other disciplines and ways of thinking. The network is well linked and we have a strong interactive relationship, particularly with Bremen. I have conversed extensively with researchers of the Jacobs University team via email and in person.
Name: Institute: Université de la Méditerranée Microbiology Aix-en-Marseille UMR-MD 1 Enveloppe bacterienne, perméabilité et antibiotique Maseille, France Alexander.Molitor@medecine.univ-mrs.fr Expertise: Alexander Molitor Doctoral thesis: `Régulation de la perméabilité membranaire chez les bactéries à Gram négatif et la relation avec la sensibilité aux antibiotiques´ (`Regulation of membrane permeability at gram negative bacteria and the relation to antibiotic resistnace`) Short CV: Since 01/2007 Doctoral thesis 09/2005 - 07/2006 Diploma thesis ´In vitro analysis of interactions between toxins and binding proteins´ at the department of biotechnology at the Biozentrum, Würzburg 07/2005 Diploma examination of biology in Biochemistry, Biotechnology, Microbiology Date of birth: 16 th August 1979 Publications: `Membrane permeability and regulation of drug « influx and efflux » in enterobacterial pathogens` - Anne Davin-Regli, Jean-Michel Bolla, Chloë James, Jean-Philippe Lavigne, Jacqueline Chevalier, Eric Garnotel, Alexander Molitor, Jean-Marie Pagès Your responsibility in the network: Genetic regulation of membrane permeability (consistent of influx and efflux) in E. aerogenes. Special attention drawn to the ram-regulator gene only present in K. pneumoniae, Salmonella, E. cloaceae and E. aerogenes. Your experience (positive/negative) with our network up to now: At the moment I only have made good experiences with the Marie Curie Research Training Network. As far as I can say, the networking between the different groups works quite well. There is a vast exchange of information and knowledge. In my opinion, the most interesting part is to have the possibility to contact experts in several different fields, e.g. such as microbiologists and physicists. In my personal researches, it is very good to have the oppurtunity to work in a close network between microbiology, pharmacy and medecine. So I think this strong connection of different fields of research also helps PhD-students like me, to get new points of view and new ideas on their own work.
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Marie Curie Fellow - faculty.jacobs-university.de - Jacobs University

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