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Kyla Dayag's 200 Drugs Booklet

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Coumadin (Warfarin)<br />

WAR-far-in<br />

Classification: Vitamin K Antagonist<br />

IFU: Anticoagulation<br />

Action: Inhibits vitamin K-dependent activation of clotting<br />

factors II, VII, IX, X, formed in the liver.<br />

Dosage: 1 mg, 2 mg, 2.5 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7.5<br />

mg, 10 mg<br />

Route: P.O., I.V.<br />

Adverse Reaction: headache, nausea, hematuria,<br />

jaundice, dermatitis, necrosis, fever, vomiting, cramps<br />

Interactions: Acetaminophen: May increase bleeding with<br />

long-term therapy (more than 2 weeks) at high doses<br />

(more than 2g/day) of acetaminophen

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