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Hepcidin (Liver Expressed Antimicrobial Peptide 1 or Putative Liver Tumor Regressor or HAMP)-Pipeline Review, H1 2017

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<strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong><br />

Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>)-<strong>Pipeline</strong> <strong>Review</strong>, <strong>H1</strong> <strong>2017</strong><br />

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Description:<br />

<strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>) -<br />

<strong>Hepcidin</strong> is a protein encoded by the <strong>HAMP</strong> gene. It acts by promoting endocytosis and<br />

degradation of ferrop<strong>or</strong>tin leading to the retention of iron in iron exp<strong>or</strong>ting cells and decreased<br />

flow of iron into plasma. It controls the maj<strong>or</strong> flows of iron into plasma, abs<strong>or</strong>ption of dietary<br />

iron in the intestine and recycling of iron by macrophages.<br />

<strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>)<br />

pipeline Target constitutes close to 6 molecules. Out of which approximately 6 molecules are<br />

developed by Companies. The molecules developed by companies in Phase II, Preclinical and<br />

Discovery stages are 2, 3 and 1 respectively. Rep<strong>or</strong>t covers products from therapy areas<br />

Hematological Dis<strong>or</strong>ders, Genetic Dis<strong>or</strong>ders, Immunology, Oncology and Toxicology which<br />

include indications Hemochromatosis, Thalassemia, Acute Inflammation, Anemia, Anemia in<br />

Chronic Kidney Disease (Renal Anemia), Anemia of Chronic Disease, Chemotherapy Induced<br />

Anemia, Iron Deficiency Anemia, Polycythemia Vera and Sickle Cell Disease.<br />

Request a sample of this rep<strong>or</strong>t @ http://www.<strong>or</strong>bisresearch.com/contacts/requestsample/310026<br />

.<br />

The latest rep<strong>or</strong>t <strong>Hepcidin</strong> - <strong>Pipeline</strong> <strong>Review</strong>, <strong>H1</strong> <strong>2017</strong>, outlays comprehensive inf<strong>or</strong>mation on<br />

the <strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong><br />

<strong>HAMP</strong>) targeted therapeutics, complete with analysis by indications, stage of development,<br />

mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews<br />

key players involved in <strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong><br />

Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>) targeted therapeutics development with respective active and<br />

d<strong>or</strong>mant <strong>or</strong> discontinued projects.<br />

The rep<strong>or</strong>t is built using data and inf<strong>or</strong>mation sourced from proprietary databases,<br />

company/university websites, clinical trial registries, conferences, SEC filings, invest<strong>or</strong><br />

presentations and featured press releases from company/university sites and industry-specific<br />

third party sources.<br />

Scope<br />

- The rep<strong>or</strong>t provides a snapshot of the global therapeutic landscape f<strong>or</strong> <strong>Hepcidin</strong> (<strong>Liver</strong><br />

<strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>)<br />

- The rep<strong>or</strong>t reviews <strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong><br />

Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>)targeted therapeutics under development by companies and<br />

universities/research institutes based on inf<strong>or</strong>mation derived from company and industryspecific<br />

sources<br />

- The rep<strong>or</strong>t covers pipeline products based on various stages of development ranging from<br />

pre-registration till discovery and undisclosed stages<br />

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- The rep<strong>or</strong>t features descriptive drug profiles f<strong>or</strong> the pipeline products which includes, product<br />

description, descriptive MoA, R&D brief, licensing and collab<strong>or</strong>ation details & other<br />

developmental activities<br />

- The rep<strong>or</strong>t reviews key players involved in <strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1<br />

<strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>)targeted therapeutics and enlists all their maj<strong>or</strong><br />

and min<strong>or</strong> projects<br />

- The rep<strong>or</strong>t assesses <strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong><br />

Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>) targeted therapeutics based on mechanism of action (MoA), route of<br />

administration (RoA) and molecule type<br />

- The rep<strong>or</strong>t summarizes all the d<strong>or</strong>mant and discontinued pipeline projects<br />

- The rep<strong>or</strong>t reviews latest news and deals related to <strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong> <strong>Antimicrobial</strong><br />

<strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>) targeted therapeutics<br />

Browse the full rep<strong>or</strong>t @ http://www.<strong>or</strong>bisresearch.com/rep<strong>or</strong>ts/index/hepcidin-liverexpressed-antimicrobial-peptide-1-<strong>or</strong>-putative-liver-tum<strong>or</strong>-regress<strong>or</strong>-<strong>or</strong>-hamp-pipelinereview-h1-<strong>2017</strong><br />

.<br />

Reasons to buy<br />

- Gain strategically significant competit<strong>or</strong> inf<strong>or</strong>mation, analysis, and insights to f<strong>or</strong>mulate<br />

effective R&D strategies<br />

- Identify emerging players with potentially strong product p<strong>or</strong>tfolio and create effective<br />

counter-strategies to gain competitive advantage<br />

- Identify and understand the targeted therapy areas and indications f<strong>or</strong> <strong>Hepcidin</strong> (<strong>Liver</strong><br />

<strong>Expressed</strong> <strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>)<br />

- Identify the use of drugs f<strong>or</strong> target identification and drug repurposing<br />

- Identify potential new clients <strong>or</strong> partners in the target demographic<br />

- Develop strategic initiatives by understanding the focus areas of leading companies<br />

- Plan mergers and acquisitions effectively by identifying key players and it’s most promising<br />

pipeline therapeutics<br />

- Devise c<strong>or</strong>rective measures f<strong>or</strong> pipeline projects by understanding <strong>Hepcidin</strong> (<strong>Liver</strong> <strong>Expressed</strong><br />

<strong>Antimicrobial</strong> <strong>Peptide</strong> 1 <strong>or</strong> <strong>Putative</strong> <strong>Liver</strong> Tum<strong>or</strong> Regress<strong>or</strong> <strong>or</strong> <strong>HAMP</strong>)development landscape<br />

- Develop and design in-licensing and out-licensing strategies by identifying prospective<br />

partners with the most attractive projects to enhance and expand business potential and scope<br />

Companies Mentioned<br />

Daiichi Sankyo Company Ltd<br />

Noxxon Pharma AG<br />

Pieris Pharmaceuticals Inc<br />

Protagonist Therapeutics Inc<br />

Purchase a copy of this rep<strong>or</strong>t @ http://www.<strong>or</strong>bisresearch.com/contact/purchase/310026 .<br />

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