EUROPE TRANSCATHETER AORTIC VALVE REPLACEMENT MARKET

RESEARCH REPORT
DECEMBER 2017
EUROPE TRANSCATHETER AORTIC VALVE
REPLACEMENT MARKET
SEGMENTED BY SURGERY METHOD, BY VALVE FRAME MATERIAL, BY
VALAVE SIZE, BY END-USER AND REGION-INDUSTRY ANALYSIS, SIZE,
SHARE, GROWTH, TRENDS AND FORECASTS 2016-2021

Europe transcatheter aortic valve replacement (TAVR) market is expected to reach USD 1.06
billion by 2021 from USD 0.47 billion in 2016, growing at a CAGR of 17.40% during the
forecast period 2016-2021. Transcatheter aortic valve replacement (TAVR) is described as
minimally invasive procedure replaces the improper functioning aortic valves. TAVR offers
an efficient valve replacement procedure as compared to open-heart surgery for the benefit
of high risk patients. Transcatheter heart valve replacement systems are referred as
cardiovascular devices replace the old and damaged valves. TAVR is used for the treatment
of aortic valve disorders such as severe aortic stenosis, degeneration, & regurgitation.
Transcatheter aortic valve replacement devices are integrated with valve frame (made of
nitinol or stainless steel), valve leaflets material (made of bovine or cow heart tissue). These
aortic valves are available with varied sizes (such as 14mm, 16mm, 18mm, 20mm, 22mm, &
29mm). TAVR is performed during different surgery methods such as transfemoral
implantation (through the femoral artery), transapical implantation (through the apex of the
heart), transaortic implantation (through the top of right chest), and transcaval implantation
(through the femoral vein).
Increasing technological advancements in biomedical engineering, presence of advanced
cardiovascular healthcare industry, existence of healthcare specialists & equipment, and
growing demand for healthy lifestyle are driving the growth of transcatheter aortic valve
replacement (TAVR) market in Europe. However, stringent regulatory guidelines and high
cost of the TAVR procedures are expected to restrain the growth of transcatheter aortic
valve replacement (TAVR) market in Europe.
Europe transcatheter aortic valve replacement (TAVR) market is segmented based on
surgery method, valve frame material, valve size, valve leaflets material, and end users.
Based on surgery method, the market is sub-segmented as transfemoral implantation,
transapical implantation, transaortic implantation, and transcaval implantation. Of these,
transfemoral is estimated to command the largest share of Europe transcatheter aortic
valve replacement (TAVR) market by surgery method in 2016 and expected to grow at the
highest CAGR during the forecast period. Based on valve frame material, the market is
segmented as nitinol, stainless steel, and cobalt-chromium. Of these, nitinol segment is
expected to account for the largest share of Europe transcatheter aortic valve replacement
(TAVR) market by valve frame material in 2016.
Transcatheter valve size market is segmented as 14mm to 18mm, 18mm to 22mm, and
22mm to 29mm. Based on valve leaflets material, the market is segmented as bovine heart
tissue, cow heart tissue, and other valve leaflets material. Based on end users, the market is
sub-segmented as hospitals, ambulatory surgical centres, & cardiac catheterization
laboratories. Of these, hospital segment held the largest share of Europe transcatheter
aortic valve replacement (TAVR) market by end users in 2016.
On the basis of geographical areas, Europe transcatheter aortic valve replacement (TAVR)
market is segmented as U.K., Germany, France, Italy, and Spain.

Market Segmentation:
1 Introduction
2 Surgery Method
2.1 Introduction
2.2 Transfemoral Implantation
2.3 Transapical Implantation
2.4 Transaortic Implantation
2.5 Transcaval Implantation
3 Valve Material
3.1 Introduction
3.2 Nitinol
3.3 Stainless Steel
3.4 Cobalt-Chromium
4 Valve Size
4.1 Introduction
4.2 14mm to 18 mm
4.3 18mm to 22 mm
4.4 22mm to 29mm
5 Valve Leaflets Material
1 Introduction
2 Bovine Heart Tissue
3 Cow Heart Tissue
4 Other Valve Leaflets Material
6 End Users

6.1 Introduction
6.2 Hospitals
6.3 Ambulatory Surgical Centres
6.4 Cardiac Catheterization Laboratories
The key players in transcatheter aortic valve replacement (TAVR) market such as, Edwards
Lifesciences Corporation (U.S.), Medtronic, Inc. (Ireland), Boston Scientific Corporation
(U.S.), Abbott Laboratories (U.S.), St. Jude Medical Inc. (U.S.), JenaValve Technology, Inc.
(Germany), Symetis SA (Switzerland), Direct Flow Medical, Inc. (U.S.), Sorin Group (Italy),
Meril Life Sciences India Pvt Ltd (India), and Braile Biomedica (Brazil).
TABLE OF CONTENTS
1. Introduction
1.1 Market Definition
1.2 Study Deliverables
1.3 Base Currency, Base Year and Forecast Periods
1.4 General Study Assumptions
2. Research Methodology
2.1 Introduction
2.2 Research Phases
2.2.1 Secondary Research
2.2.2 Primary Research
2.2.3 Econometric Modelling
2.2.4 Expert Validation

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2.3 Analysis Design
2.4 Study Timeline
3. Overview
3.1 Executive Summary
3.2 Key Inferences
4. Drivers, Restraints, Opportunities, and Challenges Analysis (DROC)
4.1 Market Drivers
4.2 Market Restraints
4.3 Key Challenges
4.4 Current Opportunities in the Market
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5. Market Segmentation
5.1 Introduction
5.2 Surgery Method
5.2.1 Introduction
5.2.2 Transfemoral Implantation
5.2.3 Transapical Implantation
5.2.4 Transaortic Implantation
5.2.5 Transcaval Implantation
5.3 Valve Material

5.3.1 Introduction
5.3.2 Nitinol
5.3.3 Stainless Steel
5.3.4 Cobalt-Chromium
5.4 Valve Size
5.4.1 Introduction
5.4.2 14mm to 18 mm
5.4.3 18mm to 22 mm
5.4.4 22mm to 29mm
5.5 Valve Leaflets Material
5.5.1 Introduction
5.5.2 Bovine Heart Tissue
5.5.3 Cow Heart Tissue
5.5.4 Other Valve Leaflets Material
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5.6 End Users
5.6.1 Introduction
5.6.2 Hospitals
5.6.3 Ambulatory Surgical Centres
5.6.4 Cardiac Catheterization Laboratories
6. Geographical Analysis
6.2.1 Introduction
6.2.2 U.K
6.2.3 Spain
6.2.4 Germany

6.2.5 Italy
6.2.6 France
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7. Strategic Analysis
7.1 PESTLE analysis
7.1.1 Political
7.1.2 Economic
7.1.3 Social
7.1.4 Technological
7.1.5 Legal
7.1.6 Environmental
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7.2 Porter’s Five analysis
7.2.1 Bargaining Power of Suppliers
7.2.2 Bargaining Power of Consumers
7.2.3 Threat of New Entrants
7.2.4 Threat of Substitute Products and Services
7.2.5 Competitive Rivalry within the Industry
8. Market Leaders' Analysis

8.1 Edwards Lifesciences Corporation (U.S.)
8.1.1 Overview
8.1.2 Product Analysis
8.1.3 Strategic Evaluation and Operations
8.1.4 Financial analysis
8.1.5 Legal issues
8.1.6 Recent Developments
8.1.7 SWOT analysis
8.1.8 Analyst View
8.2 Medtronic, Inc. (Ireland)
8.3 Boston Scientific Corporation (U.S.)
8.4 Abbott Laboratories (U.S.)
8.5 St. Jude Medical Inc. (U.S.)
8.6 JenaValve Technology, Inc. (Germany)
8.7 Symetis SA (Switzerland)
8.8 Direct Flow Medical, Inc. (U.S.)
8.9 Sorin Group (Italy)
8.10 Meril Life Sciences India Pvt Ltd (India)
8.11 Braile Biomedica (Brazil)
9. Competitive Landscape
9.1 Market share analysis
9.2 Merger and Acquisition Analysis

9.3 Agreements, collaborations and Joint Ventures
9.4 New Product Launches
10. Market Outlook and Investment Opportunities
Appendix
a) List of Tables
b) List of Figures
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SCOPE OF THE REPORT
Global, regional and country-level analysis and forecasts of the study market;
providing Insights on the major countries/regions in which this industry is blooming
and to also identify the regions that are still untapped
Identification of key drivers, restraints, opportunities, and challenges (DROC) in the
market and their impact on shifting market dynamics
Study of the effect of exogenous and endogenous factors that affect the global
market; which includes broadly demographic, economics, and political, among other
macro-environmental factors presented in an extensive PESTLE Analysis

Study the micro environment factors that determine the overall profitability of an
Industry, using Porter’s five forces analysis for analyzing the level of competition
and business strategy development
A comprehensive list of key market players along with their product portfolio,
current strategic interests, key financial information, legal issues, SWOT analysis and
analyst overview to study and sustain the market environment
An executive summary, abridging the entire report in such a way that decisionmaking
personnel can rapidly become acquainted with background information,
concise analysis and main conclusions
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