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South African Women's Health - November 2017

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ISSN 2522-3941<br />

ABOUT best practice, FOR FOR optimal care<br />

careissue 1• 2 • aug/sept nov/dec <strong>2017</strong><br />

www.southafricanwomenshealth.co.za


Focus on<br />

SURGICAL BIOPSY<br />

VS CORE BIOPSY<br />

8<br />

WHEN LESS IS MORE<br />

17<br />

IT’S IN THE DNA<br />

35<br />

THE ROLE OF FAT GRAFTING<br />

IN AESTHETIC SURGERY<br />

PROGNOSTIC & PREDICTIVE<br />

38<br />

VACCINES: THE LOW DOWN<br />

44<br />

MARKERS IN BREAST CANCER<br />

SOUTH AFRICA’S OBSESSION<br />

WITH FOOD<br />

46<br />

HOW GASTRIC BYSPASS<br />

PATIENTS LEARN TO EAT AGAIN<br />

NOTE: “instructions to authors” are available at www.southafricanwomenshealth.co.za<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 3


CONTENTS<br />

NOVEMBER <strong>2017</strong><br />

5 FROM THE EDITOR<br />

6 FOCUS ON: SUB-EDITOR BIOGRAPHIES<br />

BREAST<br />

8 FOCUS ON: SURGICAL BIOPSY VS CORE BIOPSY:<br />

WHEN LESS IS MORE<br />

10 FOCUS ON: NEW TRENDS IN BREAST CANCER: MANAGEMENT<br />

& RECONSTRUCTION SURGICAL PERSPECTIVE<br />

15 GROOTE SCHUUR HOSPITAL BREAST CLINIC<br />

WOMEN IN HEALTHCARE<br />

17 FOCUS ON: IT’S IN THE DNA<br />

19 A WOMAN’S TALE<br />

23 SOUTH AFRICAN TAX AND DNA<br />

25 BE BOLD FOR CHANGE <strong>2017</strong><br />

27 STOPPING THE BLUR<br />

OBSTETRICS & GYNAECOLOGY<br />

29 HOW SOPHROLOGY HELPS PREGNANCY:<br />

A WOMAN’S JOURNEY BEFORE, DURING & AFTER<br />

AESTHETICS & RECONSTRUCTION<br />

35 FOCUS ON: THE ROLE OF FAT GRAFTING<br />

IN AESTHETIC SURGERY<br />

HEALTH & LIFESTYLE<br />

38 VACCINES: THE LOW DOWN<br />

40 IZZY’S STORY<br />

42 FOCUS ON: CHILDHOOD OBESITY AND WHY IT MATTERS<br />

WHAT CHILDEN EAT AT SCHOOL<br />

ONCOLOGY<br />

44 PROGNOSTIC & PREDICTIVE MARKERS IN BREAST CANCER<br />

SURGERY, OBESITY & METABOLISM<br />

46 SOUTH AFRICA’S CULTURAL OBSESSION WITH FOOD &<br />

THE PSYCHOLOGY OF WEIGHT LOSS HOW GASTRIC BYPASS<br />

PATIENTS ‘LEARN TO EAT AGAIN’<br />

* PLEASE NOTE: Each item is available as full text electronically and as an individual pdf online.<br />

Disclaimer: No responsibility will be accepted for any statement made or opinion expressed in the publication.<br />

Consequently, nobody connected with the publication including directors, employees or editorial team will be held liable for any<br />

opinion, loss or damage sustained by a reader as a result of an action or reliance upon any statement or opinion expressed.<br />

© <strong>South</strong> <strong>African</strong> Women’s <strong>Health</strong> This magazine is copyright under the Berne Convention. In terms of the <strong>South</strong> <strong>African</strong><br />

Copyright Act No. 98 of 1978, no part of this magazine may be reproduced or transmitted in any form or by any means,<br />

electronic or mechanical, including photocopying, recording or by any information storage and retrieval system,<br />

without the permission of the publisher and, if applicable, the author.<br />

COVER PHOTOGRAPH: Shutterstock Image<br />

Design and layout: The Source PR * Printers: Imagine It Print It<br />

4 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FROM THE EDITOR<br />

Dear Reader,<br />

Welcome to this second edition.<br />

I have thoroughly enjoyed the selection of articles sent via the<br />

various sub-editors. From one extreme of “fat positives “ of fat grafting…<br />

to obesity. Kudos to another excellent government clinic (lets hear more<br />

from others in the next edition). Loving the traction of…Woman in medicine<br />

…and thrilled to see a mentor (to myself and many) featured …Prof Kramer.<br />

Thank you to the behind the scenes team.<br />

I encourage all reading this journal to send their articles and comments.<br />

We want to hear and read about your work...as there is no doubt to the excellent quality of medical<br />

work and insights in our wonderful country.<br />

Carol Benn<br />

Editor-in-Chief<br />

Editor-in-Chief: Carol Benn - Head, Breast Unit, Helen Joseph Hospital, Netcare Breast Centre<br />

Associate Editor: Christopher P. Szabo - Head, Department of Psychiatry, University of Witwatersrand<br />

Advisory Board: Karen Appelbaum - Psychologist, Netcare Milpark Hospital<br />

Georgia Demetriou - Department of Oncology, Charlotte Maxeke Johannesburg Academic Hospital<br />

Franco Guidozzi - Faculty of <strong>Health</strong> Sciences, University of Witwatersrand<br />

Inge Kriel - Oncology Care Physician, Milpark Breast Care Centre of Excellence<br />

Anna Sparaco - HPB practice, Wits Donald Gordon Medical Centre<br />

Tess Van Der Merwe - Honorary Professor and Researcher in the Department of Endocrinology, University of Pretoria<br />

Marisse Venter - Plastic and Reconstructive Surgeon, Netcare Milpark Hospital<br />

Acknowledgement: Thanks to Lisa Selwood for assistance with proof reading<br />

Advertising: The Source Public Relations<br />

Design and Layout: Michelle Haskins Printer: Imagine it Print It<br />

Web: www southafricanwomenshealth.co.za<br />

Contact Person: Vanessa Beyers - vanessa@thesourcepr.co.za<br />

<strong>South</strong> <strong>African</strong> Women’s <strong>Health</strong> is published quarterly by The Source Public Relations Group.<br />

Its mission is to communicate the latest news and developments in the area of <strong>South</strong> <strong>African</strong> Women’s <strong>Health</strong>.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 5


SECTION EDITORS<br />

Focus On SECTION EDITORS<br />

EDITOR & SECTION EDITOR: BREAST<br />

PROF CAROL BENN<br />

Prof Carol-Ann Benn is a Fellow of the<br />

College of Surgeons of <strong>South</strong> Africa with<br />

a special interest in Breast Disease. Her<br />

capacity as Head of the Breast Unit of<br />

Helen Joseph Hospital proves her long<br />

commitment to clinical excellence in<br />

this field of medical speciality.<br />

Prof Benn offers service to society and the greater medical<br />

community, (both local and international), through her<br />

contributions, published and presented, and she is recognised<br />

internationally as a leader in Breast Disease. As lecturer in the<br />

Department of Surgery at the University of Witwatersrand, she<br />

contributes towards the education of healthcare professionals.<br />

Through the organisation of foreign and private funding, Prof<br />

Benn was able to establish the Breast <strong>Health</strong> Foundation,<br />

various Breast <strong>Health</strong> Care forums and outreach programmes<br />

and is a representation on numerous Medical Boards and<br />

<strong>Health</strong> Care Committees. Prof Benn has paved the way for the<br />

improvement of women’s health care, has contributed towards<br />

the uplifting of women in society and has opened channels for<br />

public awareness of breast health.<br />

She established the Netcare Breast Care Centre of Excellence at<br />

Milpark Hospital, Johannesburg, which co-ordinates national<br />

efforts for the specialised management of breast conditions<br />

to all women. In addition to her positions of responsibility,<br />

Prof Benn manages continuing research and research outputs.<br />

Numerous awards testify to her esteemed position in the<br />

medical field and in <strong>South</strong> <strong>African</strong> society.<br />

SECTION EDITOR: ONCOLOGY<br />

DR GEORGIA DEMETRIOU<br />

Dr Georgia Demetriou has been a<br />

Senior Consultant in the Division of<br />

Medical Oncology at the University<br />

of Witwatersrand Faculty of <strong>Health</strong><br />

Sciences and Charlotte Maxeke<br />

Johannesburg Academic Hospital since<br />

2004 and served as Acting Head of the Division from September<br />

2013 to June 2014. She is Head of a General Medicine<br />

Undergraduate Academic teaching unit for the Department of<br />

Internal Medicine at Charlotte Maxeke Johannesburg Academic<br />

Hospital.<br />

She has been local Principal Investigator and National Principal<br />

Investigator on 15 multinational clinical trials particularly in<br />

the field Breast Cancer. Dr Demetriou serves on the Executive<br />

Committee of the <strong>South</strong> <strong>African</strong> Society of Medical Oncology as<br />

Treasurer of the society, the <strong>South</strong> <strong>African</strong> Oncology Consortium<br />

Board of Directors as Chairperson of the board and on the<br />

Executive Committee of the Breast Interest Group of <strong>South</strong> Africa<br />

as the Chairperson of the committee.<br />

She is an examiner, trainer and moderator for the Certificate<br />

Medical Oncology for College of Medicine of <strong>South</strong> Africa<br />

sub specialist qualifying degree for Medical Oncology.<br />

Dr Demetriou has co-authored papers in peer-reviewed journals,<br />

as well as presenting at local and international scientific<br />

meetings. Women’s cancers and health in particular is a major<br />

focus of work.<br />

Correspondence: georgiademetriou@hotmail.com<br />

Correspondence: drbenncarol@gmail.com<br />

SECTION EDITOR: OBSTETRICS & GYNAECOLOGY<br />

PROF FRANCO GUIDOZZI<br />

SECTION EDITOR: HEALTH & LIFESTYLE<br />

DR INGE KRIEL<br />

Dr Inge Kriel is an Oncology<br />

Care Physician affiliated with the<br />

internationally accredited Milpark<br />

Breast Care Centre of Excellence.<br />

She assists breast cancer survivors<br />

with screening for recurrence of the primary cancer and<br />

development of new cancers, management of late and longterm<br />

effects of cancer and cancer treatment, promotion of<br />

healthy lifestyle behaviours, and co-ordination of care with<br />

other oncology specialists, to ensure that patients receive the<br />

highest quality care.<br />

Correspondence: ingekriel84@gmail.com<br />

Professor Emeritus Franco Guidozzi<br />

is a Wits graduate and the erstwhile<br />

Academic Head of the Wits Department<br />

of Obstetrics and Gynaecology. He<br />

is a past President of the Society of<br />

Obstetricians and Gynaecologists,<br />

a Past President of the College of<br />

Obstetricians and Gynaecologists of<br />

the Colleges of Medicine of <strong>South</strong> Africa, a past president of<br />

the <strong>South</strong> <strong>African</strong> Menopause Society and a Past Secretary<br />

of the <strong>South</strong> <strong>African</strong> Royal College of Obstetricians and<br />

Gynaecologists.<br />

He has published over 120 articles in peer reviewed and nonpeer<br />

reviewed journals. He retired from the Wits Department<br />

of Obstetrics and Gynaecology in 2015, is still in fulltime<br />

private practice and enjoys reading, bonsai gardening and<br />

attending to his koi fish. He is married to Yolande, an advocate,<br />

has three daughters, all of whom are doctors, and loves<br />

laughing at himself.<br />

Correspondence: guidozzif@gmail.com<br />

6 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


SECTION EDITORS<br />

Focus On SECTION EDITORS<br />

SECTION EDITOR: AESTHETICS & RECONSTRUCTION<br />

DR MARISSE VENTER<br />

Dr Marisse Venter is a Plastic and<br />

Reconstructive Surgeon at Netcare<br />

Milpark Hospital. She has a special<br />

interest in breast reconstruction and<br />

cosmetic surgery. She qualified from<br />

the University of Cape Town in 2002.<br />

Her specialization encompassed 4 years of general surgery<br />

and a further 4 years of plastic surgery at the University of the<br />

Witwatersrand from where she qualified as a plastic surgeon.<br />

She is registered with the <strong>Health</strong> Professions Council of <strong>South</strong><br />

Africa as a Plastic and Reconstructive Surgeon, a member<br />

of the Association of Plastic and Reconstructive Surgeons of<br />

<strong>South</strong>ern Africa (APRSSA) and International Society of Aesthetic<br />

Plastic Surgery. Dr Venter has won numerous national and<br />

International awards for her research done on adipose<br />

tissue. Dr Venter has dedicated her life to the beautifying of<br />

women through breast reconstruction, facial, breast and body<br />

cosmetic surgery. All women deserve a body they would be<br />

comfortable with.<br />

Correspondence: dr.mventer@gmail.com<br />

SECTION EDITOR: SURGERY, OBESITY & METABOLISM<br />

(CEMMS)(SA).<br />

PROF TESS VAN DER MERWE<br />

Advisory Board member, Tess van<br />

der Merwe, is an Honorary Professor<br />

and Researcher in the Department of<br />

Endocrinology, University of Pretoria<br />

and CEO of the 11 Centres for Metabolic<br />

Medicine and Surgery of <strong>South</strong> Africa<br />

She is also the Director of the Waterfall City Hospital Metabolic<br />

Medicine and Surgery Centre Research group and is a full time<br />

clinician at this hospital.<br />

She was the Honorary Secretary of the International Association<br />

for the Study of Obesity for a period of 8 years and currently<br />

remains the Africa consultant for this association.<br />

In addition, she is the Chair of the <strong>South</strong> <strong>African</strong> Society for<br />

Surgery, Obesity and Metabolism (SASSO) and has served this<br />

organisation for more than 25 years. Professor van der Merwe<br />

established the CEMMS (SA) in 2005 and to date remains as<br />

the CEO of CEMMS(SA).<br />

SECTION EDITOR: WOMEN IN HEALTHCARE<br />

DR ANNA SPARACO<br />

Anna Sparaco is a Wits graduate,<br />

having obtained a BSc Honours in<br />

anatomical sciences under the tutelage<br />

of Prof PV Tobias. After lecturing for<br />

2 years in anatomical science,she<br />

entered her medical training at the Wits<br />

Medical School. After graduating, she spent 3 years in London<br />

at Guys and St Thomas’ culminating in gaining entrance into<br />

the Royal College of Surgeons of England. On returning to <strong>South</strong><br />

Africa, she entered into a Hepatopancreaticobiliary fellowship<br />

and concurrently was asked to join the Johannesburg transplant<br />

team and engaged in assisting in developing the liver transplant<br />

program.<br />

To this end, and having been awarded the Miller Travelling<br />

Fellowship, she spent 3 months at the University Medical Centre<br />

in Omaha, Nebraska. Subsequently, she joined Prof Rene<br />

Adam at the Hospital Paul Bruix in France where she learnt<br />

about liver resection and finally visited Professor Buchler in<br />

Heidelberg where she was exposed to aggressive pancreatic<br />

surgery. She currently has a predominantly HPB practice at<br />

the Wits Donald Gordon Medical Centre and has recently<br />

co-founded the Centre for Digestive Diseases and Liver <strong>Health</strong><br />

at the Rosebank Hospital.<br />

With the establishment of the Women’s <strong>Health</strong> Journal, she<br />

was invited to subedit a section entitled “Women in <strong>Health</strong>care”.<br />

This coincided with the creation of the Women in <strong>Health</strong>care<br />

group who’s aim is to create a virtual and social networking<br />

platform for all women in medicine. Birth was given to this<br />

group because of the realisation that the current networking<br />

structure - both formal and informal - are predominantly directed<br />

towards the male gender as they have been the predominant<br />

participants in the work space and in fact still continue to be<br />

so. WIH will endeavour to host networking functions and also to<br />

host workshops that deal with social media and your practice,<br />

flow of money through your practice, medical aid fraud and<br />

so forth. The WIH section in the journal will aim at providing<br />

similar such information and also to look at the role and profile<br />

of women in medicine.<br />

Correspondence: anna.sparaco@surgicalspecialist.co.za<br />

Correspondence: tessvdm@iafrica.com<br />

NOTE: “instructions to authors” are available at www.southafricanwomenshealth.co.za<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 7


FOCUS ON<br />

SURGICAL BIOPSY VS CORE BIOPSY<br />

Lucy Van Schalkwyk<br />

Breast complaints, specifically breast masses, should be investigated by<br />

the tried and tested process of triple assessment: the findings from three<br />

modalities – clinical examination, radiology (mammogram & ultrasound)<br />

and breast biopsy - are combined to arrive at a final diagnosis.<br />

he breast biopsy may be obtained by several<br />

different methods, which can broadly be<br />

classified as percutaneous or surgical.<br />

Percutaneous biopsies are performed<br />

by passing a hollow core biopsy needle through<br />

the skin of the breast into the suspicious lesion to<br />

extract a core of tissue (hence the synonym core<br />

biopsy), allowing for a histopathological diagnosis.<br />

Vacuum assisted biopsy, also a form of percutaneous<br />

breast biopsy, relies on a large gauge core needle<br />

attached to a vacuum-powered biopsy system to<br />

obtain several large cores of tissue. Surgical biopsy<br />

entails removal of a portion (incisional) or the whole<br />

(excisional) of a suspicious breast lesion via a skin<br />

incision, for diagnostic purposes.<br />

SURGICAL BIOPSY IS USUALLY<br />

PERFORMED UNDER GENERAL<br />

ANAESTHESIA, BUT MAY OCCASIONALLY<br />

BE PERFORMED UNDER LOCAL<br />

ANAESTHESIA.<br />

Due to its accuracy, which approaches 100%, 1<br />

surgical biopsy was historically considered the<br />

gold standard for the tissue diagnosis of breast<br />

abnormalities. Nowadays, surgical biopsy has<br />

largely been superseded by the percutaneous<br />

methods. The British Association of Breast Surgeons<br />

surgical guidelines state that in at least 90% of cases,<br />

preferably >95% of cases, breast cancer should be<br />

diagnosed by percutaneous means 2 .<br />

ACCURACY<br />

It is hardly surprising that surgical biopsy is slightly more<br />

accurate than needle biopsy – the tissue retrieved by<br />

a needle biopsy only represents a small area of the<br />

entire lesion, while surgical biopsy removes a larger<br />

portion or the entire suspicious lesion. The accuracy<br />

of needle biopsy can however be improved by<br />

imaging guidance, such as stereotactic or ultrasound<br />

guidance, which allows for visual confirmation of<br />

accurate sampling 3 .<br />

MINIMALLY INVASIVE<br />

Core needle biopsy is performed via a 3 – 4 mm<br />

stab incision in the breast, while surgical biopsy is<br />

performed though standard surgical incisions on<br />

the breast. While most surgeons attempt to place<br />

these incisions in cosmetically acceptable areas, for<br />

example peri-areolar or in the inframammary fold,<br />

poorly placed incisions are still encountered and can<br />

result in significant cosmetic disfigurement. Obtaining<br />

a diagnosis via percutaneous biopsy may spare many<br />

patients with benign pathology unnecessary scars on<br />

their breasts 4 . Core biopsies also cause less long-term<br />

distortion and scarring of the breast parenchyma 5<br />

- post-surgical fibrosis and fat necrosis can make<br />

the interpretation of subsequent mammograms<br />

challenging and may be difficult to distinguish from<br />

a malignancy.<br />

FEWER COMPLICATIONS<br />

Core biopsies are minimally invasive, and are usually<br />

performed under local anaesthesia in the outpatient<br />

setting - this significantly decreases the time to return<br />

to normal activity, compared to surgical biopsy (core<br />

biopsy: average 1.5 days, surgical biopsy average<br />

3.5 days). Core biopsies are associated with a<br />

significantly lower complication rate than surgical<br />

biopsies (surgical biopsy: 2 – 10% vs core biopsy:<br />

0.09 – 0.72%) and when complications do occur<br />

with core biopsies, they tend to be minor (e.g. minor<br />

bleeding, bruising, haematomas and mild pain) and<br />

are managed conservatively 4 .<br />

Scars from multiple poorly orientated surgical<br />

incisions on both breasts.<br />

Photograph courtesy of Professor Carol Ann Benn<br />

Scars from multiple poorly orientated surgical incisions on both breasts.<br />

Photograph courtesy of Professor Carol-Ann Benn<br />

8 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

PRE-OPERATIVE<br />

DIAGNOSIS<br />

BREAST<br />

SINGLE SURGERY<br />

Perhaps one of the greatest advantages of core<br />

needle biopsy over surgical biopsy is that patients<br />

diagnosed with breast cancer on a core biopsy are<br />

more likely to have their cancer managed in a single<br />

surgery 6-8 . The American National Accreditation<br />

Program for Breast Centres (NAPBC) states in its<br />

latest standards manual that breast units seeking<br />

accreditation should avoid surgical biopsy as an<br />

initial diagnostic approach, as it does not allow for<br />

treatment planning and is associated with a high reexcision<br />

rate 9 .<br />

IN SUMMARY:<br />

WHILE SURGICAL BIOPSY IS STILL<br />

APPROPRIATE IN SELECTED PATIENTS,<br />

PERCUTANEOUS CORE BIOPSY OFFERS<br />

MANY SIGNIFICANT ADVANTAGES AND<br />

IS NOW CONSIDERED THE STANDARD<br />

OF CARE FOR BREAST DIAGNOSIS.<br />

References:<br />

1. Bruening W, Fontanarosa J, Tipton K et al. Systematic Review: Comparative<br />

Effectiveness of Core-Needle and Open Surgical Biopsy to Diagnose Breast<br />

Lesions. Ann Intern Med. 2010;152(4):238-246.<br />

Pre-operative diagnosis affords the surgeon the<br />

opportunity to consult with appropriate specialists<br />

in the multidisciplinary cancer care team, such as<br />

radiologists, pathologists, oncologists, geneticists and<br />

plastic surgeons. It allows for planning of the surgical<br />

approach, the appropriate margin, the staging of<br />

the axilla and an appropriate reconstruction prior<br />

to placing knife to skin. Many patients are deprived<br />

of the benefit they would have derived from neoadjuvant<br />

chemotherapy by surgical biopsy 10.<br />

Despite the advantages of core needle biopsy,<br />

surgical biopsy is still indicated in certain situations,<br />

often as a supplementary procedure to a<br />

percutaneous biopsy 11 :<br />

• Lesions that are difficult to characterise on<br />

core biopsy such as atypical hyperplasia, lobular<br />

carcinoma in situ (LCIS), papillary lesions,<br />

sclerosing lesions and fibroepithelial lesions. For<br />

these lesions, a larger specimen is required to<br />

confirm the diagnosis.<br />

• A suspicious nipple discharge in the presence of<br />

a normal mammogram.<br />

• Where the suspicious lesion is in a position in the breast<br />

that is difficult to access with the biopsy needle, e.g. in<br />

close proximity to the chest wall, skin or a breast<br />

implant.<br />

• Where the findings of the triple assessment<br />

are discordant, e.g. clinical examination and<br />

mammogram are suggestive of carcinoma, but<br />

the result of the core biopsy is benign.<br />

2. Surgical Guidelines for the Management of Breast Cancer, Association<br />

of Breast Surgery at BASO 2009, Eur J Surg Onco. Retrieved from http://<br />

associationofbreastsurgery.org.uk/media/63420/surgical-guidelines-for-themanagement-of-breast-cancer-abs-baso-2009.pdf<br />

on 30/11/<strong>2017</strong><br />

3. Dillon M, Hill AK, Quinn C et al. The Accuracy of Ultrasound, Stereotactic, and<br />

Clinical Core Biopsies in the Diagnosis of Breast Cancer, With an Analysis of<br />

False-Negative Cases. Ann Surg 2005 Nov; 242(5): 701–707.<br />

4. White RR, Halperin TJ, Olson JA et al. Impact of Core-needle Breast Biopsy on<br />

the Surgical Management of Mammographic Abnormalities. Ann Surg 2001<br />

Jun;233(6):769-77.<br />

5. Dahabreh IJ, Wieland LS, Adam GP, et al. Core Needle and Open Surgical<br />

Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report [Internet].<br />

Rockville (MD): Agency for <strong>Health</strong>care Research and Quality (US); 2014 Sep.<br />

(Comparative Effectiveness Reviews, No. 139.) Results. Available from: https://<br />

www.ncbi.nlm.nih.gov/books/NBK246884/<br />

6. Kaufman CS, Delbecq R, Jacobson L. Excising the Reexcision: Stereotactic<br />

Core-needle Biopsy Decreases Need for Reexcision of Breast Cancer. World J<br />

Surg 1998 Oct;22(10):1023-7<br />

7. Yim JH, Barton P, Weber B et al. Mammographically detected breast cancer.<br />

Benefits of stereotactic core versus wire localization biopsy. Ann Surg 1996 Jun;<br />

223(6): 688–700<br />

8. James TA, Mace JL, Virnig BA et al. Preoperative Needle Biopsy Improves the<br />

Quality of Breast Cancer Surgery. J Am Coll Surg 2012 (215) 4 : 562–568<br />

9. The National Accreditation Program for Breast Centers 2018 Standards<br />

Manual. Retrieved from http://www.facs.org on 27/11/<strong>2017</strong>.<br />

10. The American Society of Breast Surgeons, Consensus Guideline on Image-<br />

Guided Percutaneous Biopsy of Palpable and Nonpalpable Breast Lesions, Nov<br />

<strong>2017</strong>. Retrieved from http://www.breastsurgeonsweb.org on 30/11/<strong>2017</strong><br />

11. The American Society of Breast Surgeons, Statement on Surgical Biopsies.<br />

Retrieved from http://www.breastsurgeonsweb.org on 27/11/<strong>2017</strong>.<br />

Lucy Van Schalkwyk: Correspondence: Please contact the relevant sub-editor, as well as cc the Editor-in-Chief<br />

for more information.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 9


FOCUS ON<br />

NEW TRENDS IN<br />

BREAST CANCER<br />

MANAGEMENT & RECONSTRUCTION<br />

SURGICAL PERSPECTIVE<br />

Carol Benn<br />

INTRODUCTION<br />

Breast cancer treatment has evolved over the<br />

last 50 years, from a disease treated mainly in the<br />

hands of the surgeon to now being a showcase for<br />

multi-disciplinary team management. Advancement<br />

in the understanding of oncological care has resulted<br />

in swings from large radical surgery (Halstedian<br />

mastectomies) to breast conserving surgery.<br />

Greater understanding of tumour biology has seen<br />

tremendous strides in the use of oncological drugs,<br />

and the paradigm shift around understanding cancer<br />

spread.<br />

SCREENING ADVANCES IN BOTH<br />

MAMMOGRAPHY, ULTRASOUND AND<br />

MRI SCANNING HAVE RESULTED IN<br />

EARLIER DETECTION OF CANCERS<br />

RESULTING IN SMALLER SURGICAL<br />

EXCISIONS IN SOME INSTANCES AS<br />

WELL AS DISCUSSION AROUND OVER<br />

OPERATING AND “UNNECESSARY<br />

MASTECTOMIES.”<br />

Advances in patient advocacy, understanding the<br />

psychological makeup of the patient and the value<br />

of breast reconstruction, particularly in immediate<br />

one-stage procedures, have necessitated a more<br />

comprehensive multi-disciplinary team approach to<br />

care.<br />

The standard surgical therapeutic option for patients<br />

with stage 1 and two breast cancers in the 21st<br />

century is breast conservation with radiation therapy.<br />

This combination has outcomes with less morbidity<br />

and at least equivalent recurrence of disease,<br />

compared to the classical radical mastectomy.<br />

Breast conservation is well supported by level 1 and<br />

2 data (National Cancer Institute, 2014) (NCCN<br />

Guidelines 2016) and is not just the thrust of women’s<br />

empowerment groups and<br />

patient preference. Survival<br />

outcomes are identical for<br />

both mastectomy and breast<br />

conserving surgery. Thus<br />

some patients may elect<br />

mastectomies.<br />

Greater public awareness<br />

regarding breast selfexamination,<br />

clinical breast<br />

Carol Benn<br />

examination, and mammographic screening<br />

have led to the detection of smaller and earlier<br />

stage breast cancers. Despite this, the incidence<br />

of advanced breast cancers has not decreased<br />

in countries with screening programmes while the<br />

incidence of advanced breast cancers remains high<br />

in LMICs without access to screening.<br />

Advanced radiological methods, including<br />

mammography, ultrasound, and MRI scanning,<br />

have detected smaller cancers allowing surgical<br />

excision with better breast conservation. Central to<br />

the acceptance of breast conservation therapy<br />

(BCT) is the importance of avoiding disfiguring<br />

cosmetic results. The conserved breast must have<br />

an acceptable aesthetic appearance. A better<br />

understanding of the psychological makeup of<br />

the cancer patient, including the importance of<br />

breast reconstruction, as an immediate one-stage<br />

procedure, has resulted in clinicians offering a wide<br />

variety of surgeries with the expectation that treating<br />

surgeons will achieve cosmetically more desirable<br />

results. Breast conserving surgery should, therefore,<br />

be considered both an oncological, as well as a<br />

cosmetic procedure, and the extent of surgical<br />

margin from the tumour will play a pivotal role in<br />

achieving this. Poor cosmetic results, due to extensive<br />

surgical resection without reconstructive techniques<br />

and radiation change, have been reported in at least<br />

20% of patients.<br />

10 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong>


PLANFOCUS<br />

A CLEAR<br />

WHO GETS WHAT SURGERY?<br />

Today there is little reason for a woman not to choose<br />

BCT.<br />

The absolute oncological indications for a<br />

mastectomy today are 2<br />

• Infla[1]mmatory breast cancer<br />

• Multicentric breast cancer<br />

Relative oncological contraindications are<br />

• Paget’s disease<br />

• Lobular Carcinomas<br />

• BRCA positive<br />

A woman may elect to have a mastectomy or a<br />

bilateral mastectomy, but this is a psychological<br />

choice, not an oncological choice (with many<br />

reasons being cited):<br />

• Strong family history<br />

• Desire to avoid radiation due to logistics<br />

or personal reasons<br />

• Sense of failure in radiology to detect a tumour<br />

either due to past experience or not wanting<br />

future mammograms<br />

• Aesthetic desires involving prosthetic reconstruction<br />

ON<br />

WHAT IS THE NEW STANDARD OF CARE IN<br />

MANAGEMENT?<br />

All patients should be discussed in the following multidisciplinary<br />

meetings;<br />

Clinical radiology meeting:<br />

In which correlation between the radiology and the<br />

core biopsy pathology is documented; including the<br />

need for further investigation.<br />

An oncology multidisciplinary meeting:<br />

The patient is discussed in the presence of all treating<br />

disciplines that play a role in the care of the patient<br />

(attending members should be from the disciplines<br />

of medical oncology; radiation oncology; radiology;<br />

pathology; surgical oncology; genetics; oncology<br />

care physicians; nurse navigation (allied care<br />

specialists: lymph oedema; physio; nutritionists).<br />

ALL DECISIONS AROUND THE ABOVE<br />

MEETINGS SHOULD BE FED BACK TO<br />

THE PATIENTS WITH A CLEAR PLAN OF<br />

ACTION AROUND TREATMENT.<br />

BEFORE ANY WOMAN DECIDES ON<br />

HER SURGERY A DETAILED DISCUSSION<br />

EXPLAINING THE FOLLOWING POINTS<br />

NEED TO BE MADE.ONCE A DIAGNOSIS<br />

OF A BREAST CANCER IS MADE; THAT<br />

CANCER DETERMINES THE OUTCOME,<br />

AND IRRESPECTIVE OF THE BRCA<br />

OR FAMILY HISTORY A BILATERAL<br />

MASTECTOMY BECOMES CHOICE NOT<br />

AN ONCOLOGICAL DECISION.<br />

The survival is equal whether a mastectomy or BCT is<br />

performed.<br />

• All woman should be counseled around the<br />

oncology rules<br />

• All woman should be discussed in a Multidisciplinary<br />

meeting<br />

• A clear plan should be presented to the patient<br />

before starting treatment<br />

• All woman should be offered the opportunity for<br />

a second opinion<br />

BREAST CANCER TREATMENT DOES<br />

NOT INVOLVE “EMERGENCY CANCER<br />

SURGERY EVER.”<br />

Breast conservation is not a contraindication in<br />

women with big tumours or woman with locally<br />

advanced breast cancer. Before discussing different<br />

surgical techniques for surgery and reconstruction lets<br />

look at oncology principles that may guide surgery<br />

choices.<br />

Each unit should have a written documentation of :<br />

• local treatment guidelines<br />

• which international guidelines are followed<br />

• which cases should be discussed that may fall<br />

outside of guidelines or require specific<br />

non-guideline based treatment choices and why<br />

DIAGNOSIS AND PATHOLOGY<br />

Radiology diagnostics includes not just mammography<br />

but also the use of breast tomosynthesis; ultrasound<br />

not just of the breast but the axilla to determine;<br />

document and perform possible needle biopsies to<br />

record lymph node involvement; Breast MRI also plays<br />

a critical role in determining extent of disease and<br />

response to oncology treatment.<br />

The gold standard of a core biopsy is critical in<br />

determining the biological profile of the breast<br />

cancer. Some units may have expertise with fine<br />

needle aspiration cytology providing the same data.<br />

Breast cancers are divided into four major subtypes:<br />

• Luminal A:<br />

• Luminal B<br />

• Her 2 enriched<br />

• Triple negative<br />

RADIATION THERAPY DISCUSSIONS<br />

All patients should have documentation of the<br />

need for radiation with breast conserving surgery.<br />

Discussions around whether the patient fits criteria<br />

for intra-operative radiation should be assessed<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 11


FOCUS ON<br />

THE PROS AND CONS<br />

according to (ASTRO <strong>2017</strong> guidelines). Need for<br />

radiation due to axillary nodal disease (1 or more<br />

involved). Whether the unit accepts and follows the<br />

Z11 protocol for radiation; thus avoiding more axillary<br />

surgery; as well as the AMAROS trial outcomes. The<br />

pros and cons of hypofractionated treatment and<br />

whether the patient fits criteria. Can radiation be<br />

avoided in certain elderly luminal A tumours.<br />

ONCOLOGY DISCUSSIONS<br />

Guidelines as to which patients do not<br />

require chemotherapy according to<br />

genetic profiling must be documented.<br />

Which patients do not require chemotherapy with<br />

node positive disease (For example: may decide<br />

extremely low Ki luminal A; low-grade lobular<br />

carcinomas )?<br />

Which early-stage breast cancer patients will start<br />

with primary chemotherapy (For example triple<br />

negatives; Her 2 enriched; High Ki luminal B)?<br />

Does your unit use specific chemotherapy regimes<br />

for different tumour subtypes? (For example TAC for<br />

triple negatives)<br />

How does your unit document response to primary<br />

chemotherapy ( clinically and radiologically)?<br />

Poor responders to primary chemotherapy are<br />

managed by:<br />

• Second line chemotherapy<br />

• Surgery<br />

Incomplete responders post chemotherapy and<br />

surgery are offered<br />

1. More oncology treatment options<br />

(CREATE for tripl negatives)<br />

2. Watch and wait<br />

What endocrine treatments are offered to what<br />

patients and for how long?<br />

1. Do you use extended adjuvant endocrine for all?<br />

2. Do you offer your young breast cancer patients an<br />

Aromatase inhibitor plus GnRH?<br />

SURGICAL PRINCIPLES<br />

Each unit should have documentation of :<br />

• What is considered an optimal surgical margin<br />

for that unit so audit of local recurrences can be<br />

monitored<br />

• Which patients are candidates for sentinel lymph<br />

node biopsies and the timing of these procedures:<br />

* At definitive surgery<br />

* Before initial surgery (in patients desiring prosthetic<br />

reconstruction wishing to avoid radiation;<br />

patients with small triple negative or Her 2<br />

enriched tumours that documentation of<br />

the extent of radiation is needed prior to<br />

starting primary chemotherapy<br />

• Patients who are candidate for intra-operative<br />

radiation therapy<br />

• Patients who can have sentinel lymph node<br />

biopsies post-primary chemotherapy once<br />

ultrasound documentation of the change of nodal<br />

status is confirmed<br />

ONCOPLASTIC PLANNING OF THE CANCER<br />

SURGERY; WITH WHAT TECHNIQUES ARE<br />

TO BE USED; WHO WILL BE PERFORMING<br />

THE SURGERY AND INTRA-OPERATIVE<br />

ASSESSMENT DOCUMENTATION OF THE<br />

SURGICAL MARGINSA PLAN OF ACTION AND<br />

PRE-SURGICAL DISCUSSION INVOLVING AT<br />

LEAST 2 SEPARATE CONSULTATIONS AROUND<br />

ONCOPLASTIC AND RECONSTRUCTIVE<br />

OPTIONS SHOULD BE DISCUSSED WITH<br />

THE PATIENT AS WELL AS WHO WILL BE<br />

PERFORMING THE SURGERY; OUTCOMES AND<br />

POTENTIAL COMPLICATIONS. ALL PATIENTS<br />

UNDERGOING PRIMARY ONCOLOGY CARE<br />

SHOULD HAVE V MARKERS PLACED PRIOR<br />

TO STARTING TREATMENT WITH CAREFUL<br />

DOCUMENTATION OF EXTENT OF DISEASE.<br />

ALLIED CARE<br />

Does your unit have radiology and oncology<br />

navigators helping patients on their cancer journey<br />

Do you offer an oncology care physician survivorship<br />

program?<br />

Are all young breast cancers offered a fertility service<br />

and discussion prior to starting treatment?<br />

What is the unit protocol on which patients are<br />

referred for genetic counseling and testing (and<br />

when)?<br />

Which patients are referred for an onco-psychology<br />

consult (and when)?<br />

Which patients are referred for lymph oedema physio<br />

(and when)?<br />

What is the unit policy on complementary oncology<br />

care and how is this managed<br />

Lets now discuss principles of oncoplastic surgery and<br />

reconstruction.<br />

THE DEFINITIONS<br />

Oncoplastic surgery is defined as techniques used at<br />

the time of breast conserving surgery. Whereas this<br />

term has been used for many years it is my opinion that<br />

it should be termed onco-reconstructive techniques.<br />

12 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong>


FOCUS ON<br />

ONCOLOGY PRINCIPLES<br />

ALLIED CARE<br />

Does your unit have radiology and oncology<br />

navigators helping patients on their cancer journey<br />

Do you offer an oncology care physician survivorship<br />

program?<br />

Are all young breast cancers offered a fertility service<br />

and discussion prior to starting treatment?<br />

What is the unit protocol on which patients are<br />

referred for genetic counseling and testing (and<br />

when)?<br />

Which patients are referred for an onco-psychology<br />

consult (and when)?<br />

Which patients are referred for lymph oedema physio<br />

(and when)?<br />

What is the unit policy on complementary oncology<br />

care and how is this managed?<br />

Lets now discuss principles of oncoplastic surgery and<br />

reconstruction.<br />

THE DEFINITIONS<br />

ONCOPLASTIC SURGERY IS DEFINED<br />

AS TECHNIQUES USED AT THE TIME OF<br />

BREAST CONSERVING SURGERY.<br />

Whereas this term has been used for many years<br />

it is my opinion that it should be termed oncoreconstructive<br />

techniques.The basis of this surgery<br />

is around understanding techniques used during<br />

breast plastic surgery; as soon as the word plastic is<br />

associated with cancer, there is often an unrealistic<br />

patient expectation.Reconstructive breast surgery is<br />

the term used for reconstruction post mastectomy be<br />

it immediate; immediate-delayed or delayed.<br />

THE FIRST RULES<br />

1. Breast reconstruction and oncoplastic surgery<br />

should be discussed with all patients prior to<br />

surgery.<br />

2. The vast majority of patients can undergo<br />

immediate reconstruction at the time of their<br />

cancer surgery (thus avoiding multiple procedures)<br />

3. Understanding the oncology principles and<br />

rules in your unit avoids unnecessary complications<br />

around reconstruction (such as which patients<br />

require radiation)<br />

THE PRINCIPLES:<br />

Tumour Factors<br />

• Understand the size of the tumour;<br />

• The position of the tumour;<br />

• The radiological and tumour information<br />

• The relationship with nipple areolar complex<br />

complex<br />

• Distance to skin<br />

Breast Factors<br />

• the size of the breast;<br />

• the consistency of the breast tissue (fatty breast<br />

can be harder to perform oncoplastic techniques<br />

on if one does not have experience the tissue pulls<br />

apart and areas of fat necrosis result from<br />

inadequate blood supply<br />

• The degree of ptosis<br />

• Previous breast surgery<br />

• Presence of prostheses (type; size and age)<br />

Patient Factors<br />

• Medical illness that may affect surgery<br />

• Habits: such as smoking<br />

• Medication that may affect surgery<br />

THE TECHNIQUES<br />

Breast conserving surgery techniques are twofold:<br />

Volume displacement:<br />

Involves moving the breast tissue around with types<br />

of parenchymal flaps. From small rotational flaps to<br />

the use of a variety of breast reduction or mastopexy<br />

techniques.<br />

Volume replacement<br />

This involves the use of importing loco-regional tissue<br />

in the vicinity of the breast cancer excision. In our<br />

unit LICAp flaps; Thoraco-epigastric flaps and regional<br />

local flaps are used commonly (with latissimus dorsi<br />

flaps used mainly for immediate or immediatedelayed<br />

medium breast reconstruction in patients<br />

post-primary chemotherapy.<br />

MASTECTOMY BASED RECONSTRUCTION<br />

Most mastectomies in our unit are skin sparing<br />

with 60% of this being nipple and skin sparing. This<br />

can be either prosthetic or autologous. Prosthetic<br />

reconstruction is mainly direct implant reconstruction<br />

in our unit without ADM (acellular dermal matrixes).<br />

The use of expander or prosthetic with ADM is reserved<br />

for a small subset of patients who have skin loss<br />

particularly in the lower poles. Prosthetic reconstruction<br />

is done once need for radiation has been accessed<br />

and is avoided in patients requiring radiation.<br />

AUTOLOGOUS RECONSTRUCTION<br />

The latissimus flap reconstruction:<br />

It is the leading workhorse in our unit in patients<br />

presenting with locally advanced breast cancer<br />

post-primary chemotherapy including in our<br />

inflammatory breast cancers. Most of these patients<br />

require immediate, delayed reconstruction involving<br />

a nipple and skin sparing mastectomy (a 48hour<br />

pathology turn-around on margins (10mm) with<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 13


margin clearance; reconstruction with the lat and<br />

OSM 48 hours later.Detailed patient counseling is<br />

suggested with a small subset of patients requiring<br />

free flaps and strict “no time delay to either radiation<br />

or chemotherapy being maintained within the unit of<br />

a minimum of 3 weeks and max allowed of 6 weeks.<br />

The Goldilocks reconstruction:<br />

Done with a modification of Nipple and skin sparing<br />

through a lateral Type 4 approach; with the addition<br />

of bilateral TE flaps is offered in some patients with<br />

breast ptosis; and over a c cup breast size.<br />

Special scenarios:<br />

The unit has a high number of locally advanced<br />

patients that are managed including those with<br />

stable or responsive metastatic disease that are<br />

offered surgery with reconstruction.<br />

A less is more approach is taken with metastatic<br />

patients requesting some form of reconstructive<br />

surgery; with the most conventional techniques being<br />

BCT with parenchymal flap reconstructions.<br />

Pregnant breast cancer patient requiring surgery<br />

also are offered local small parenchymal flap<br />

reconstruction. Elderly patients are also offered<br />

oncoplastic and breast reconstruction as long as<br />

anesthetic safety has been predetermined.<br />

IN CONCLUSION<br />

This era of breast cancer management offers for<br />

surgeons dynamic and different treatment options<br />

for patients. Today’s oncology surgeon needs to<br />

be trained in all aspects of breast cancer care<br />

from radiology to radiation. He/she needs to have<br />

comprehensive training in different plastic and<br />

reconstructive techniques to recognize which<br />

patients for which procedures and to ensure that they<br />

work with a team of competent specialists including<br />

plastic /and reconstructive surgeons so as allow best<br />

patient outcomes for their patients.<br />

References:<br />

• Extent of Primary Breast Cancer Surgery: Standards and ... - NCBI - NIH.” 22<br />

Oct. 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518938/. Accessed<br />

4 Dec. <strong>2017</strong>.<br />

• Survival is Better After Breast Conserving Therapy than Mastectomy ....” 6 Mar.<br />

2015, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595537/. Accessed 4<br />

Dec. <strong>2017</strong>.<br />

• “Clinical Practice Statements - American Society for Radiation Oncology.”<br />

https://www.astro.org/Clinical-Practice-Statements.aspx. Accessed 4 Dec. <strong>2017</strong>.<br />

• “Radiation field design in the ACOSOG Z0011 (Alliance) Trial..” 18 Aug. 2014,<br />

https://www.ncbi.nlm.nih.gov/pubmed/25135994. Accessed 4 Dec. <strong>2017</strong>.<br />

• “Regional nodal management in the light of the AMAROS trial.” https://www.<br />

ncbi.nlm.nih.gov/pmc/articles/PMC4430731/. Accessed 4 Dec. <strong>2017</strong>.<br />

Carol Benn: Head, Breast Unit, Helen Joseph Hospital. Correspondence: drbenncarol@gmail.com<br />

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FOCUS ON<br />

GROOTE SCHUUR<br />

HOSPITAL<br />

BREAST CLINIC<br />

Francois Malherbe<br />

The Groote Schuur Hospital breast clinic was founded in 1951 by Professor Jannie Louw and<br />

since then has grown into a world class centre of excellence with all the modern diagnostic<br />

and treatment facilities needed to treat patients presenting with both benign and malignant<br />

breast pathology.<br />

roote Schuur Hospital (GSH) has a<br />

population of 3.1 million people within<br />

its catchment area which includes the<br />

western part of Cape Town and the<br />

West Coast region. The main referral base includes<br />

44 clinics, of which 35 are City <strong>Health</strong> facilities, and<br />

general practitioners. GSH serves as a safety net for<br />

patients in the Northern Suburbs of Cape Town, other<br />

provinces, and patients beyond our borders.<br />

IN 2016 WE DIAGNOSED 572 NEW<br />

PATIENTS WITH BREAST CANCER.<br />

ALTHOUGH BREAST CANCER IS THE<br />

MOST DEVASTATING DIAGNOSIS, THE<br />

MAJORITY (87%) OF THE 4339 NEW<br />

PATIENTS SEEN IN 2016 PRESENTED WITH<br />

BENIGN BREAST DISEASE.<br />

The clinic is staffed by 2 permanent surgical<br />

consultants, 1 senior registrar / breast fellow, 2<br />

part-time surgical consultants, 2 part-time general<br />

practitioners with an interest in breast diseases, 1<br />

oncology registrar, 1 breast radiologist, 2 cytology<br />

technologists, 2 mammographers and a social worker.<br />

The clinic is open every Friday on the G-Floor in<br />

the outpatient building on the GSH premises. The<br />

clinic offers breast imaging, biopsy and oncology<br />

consultation of newly diagnosed positive breast<br />

cancers. Social and counselling services are also<br />

available on-site to assist newly diagnosed patients.<br />

Francois Malherbe<br />

In 1982 an on-site, real time<br />

cytology service was established<br />

under the guidance of Professor<br />

Dent, Dr Hacking and Dr<br />

Learmonth. To this day it is still one<br />

of only a few such services offered<br />

around the globe. Patients with<br />

palpable breast lumps receive a<br />

same day fine needle aspiration<br />

and cytology results<br />

IT RELIEVES A LOT OF THE ANXIETY<br />

ASSOCIATED WITH WAITING FOR A<br />

RESULT AFTER A BIOPSY FOR A BREAST<br />

LUMP.<br />

Referral criteria include all patients with a clinical<br />

suspicion of breast cancer. Therefore all women or<br />

men older than 30 years with a palpable breast<br />

lump, a spontaneous or bloody nipple discharge,<br />

new onset nipple retraction, ulceration or any<br />

other clinical features that raise the suspicion of a<br />

breast cancer will be attended to on the same<br />

day of referral. We make provision to see 80 new<br />

patients each week but during the busy period<br />

of October to December this number can often<br />

double. If the clinic is overwhelmed by the<br />

number of referrals,we make use of a triage<br />

system and provide the younger patients and<br />

patients with mastalgia without a breast lump<br />

with an elective date, usually within 2 weeks.<br />

15 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

OUR BIGGEST CHALLENGE IS<br />

MANAGING THE BREAST IMAGING<br />

Cyto-technologists hard at work<br />

Our biggest challenge is managing the breast<br />

imaging service with the available resources.<br />

Currently the waiting time for a routine mammogram<br />

IN A PATIENT WHO DOES NOT HAVE<br />

A PALPABLE LUMP STANDS AT 22<br />

WEEKS, WHILE THE WAITING TIME FOR<br />

A ROUTINE ULTRASOUND IS 10 WEEKS.<br />

We have recently acquired an ultrasound machine<br />

in the clinic and young patients are now receiving<br />

an ultrasound examination done by one of the<br />

senior clinicians on the day of their first visit<br />

which is making a significant impact on the<br />

ultrasound waiting times.<br />

With the support of Pink Drive we are trying to reduce<br />

the mammogram waiting times but the sheer volume<br />

of patients seen makes this extremely difficult.<br />

At the Groote Schuur Breast clinic we strive to detect<br />

breast problems at the earliest stage, differentiate<br />

between benign and malignant breast problems, plan<br />

effective management and follow up and counsel<br />

the patient and his/her attendants adequately.<br />

APPOINTMENTS CAN BE MADE VIA<br />

THE GSH OUTPATIENTS CALL CENTRE AT<br />

(021) 404 5566 OR ANY QUERIES CAN<br />

BE DIRECTED TO OUR EMAIL ADDRESS<br />

GSHSURGONC@GMAIL.COM<br />

Nursing Staff in the clinic<br />

Francois Malherbe: Graduated with a FCS(SA) and MMed(UCT) in 2011. Since 2014, after a short period working as a general<br />

surgeon at New Somerset Hospital in Cape Town, he has been back full time at the Groote Schuur Hospital breast and surgical<br />

endocrine unit. His clinical interests are oncoplastic breast surgery, breast cancer research, surgical oncology and endocrine<br />

neoplasms (thyroid, parathyroid, adrenal). Correspondence: francois.malherbe@uct.ac.za<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 16


FOCUS ON<br />

17 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


IT’S IN THE<br />

FOCUS ON<br />

DNA<br />

WOMEN IN HEALTHCARE<br />

Anna Sparaco<br />

What a formative year. This is the year<br />

that the double X chromosome took<br />

traction. As the title of the formidable<br />

Judy Dlamini books states “Equal but<br />

different.” This year saw the introduction of the<br />

Women <strong>Health</strong> Journal and Women in <strong>Health</strong>care<br />

Africa consolidated its footprint.<br />

In this issue, Prof Bev Kamer reflects back on her career<br />

in <strong>Health</strong> Sciences and influences that have made<br />

her who she is. Donne Botha, dynamic manager at<br />

Boston Scientific, gives us some industry perspectives<br />

and touches on stressors. Our resident coach Colleen<br />

Qvist reminds us to be grateful and mindful of our<br />

blessings and achievements.<br />

In a series of 3 financial workshops hosted and<br />

generously supported by Mundipharm, Women in<br />

<strong>Health</strong>care Africa tackled our biggest fear – money<br />

management in our practices. The main concerns<br />

were around understanding tax. Joanne Williams,<br />

from Leading Accounting, summarizes some of the<br />

discussion.<br />

WE FINISH <strong>2017</strong> FEELING THAT SOME STRIDES<br />

HAVE BEEN MADE IN RECOGNIZING<br />

THAT THE XX CHROMOSOME MAKES US<br />

DIFFERENT BUT THAT THESE DIFFERENCES<br />

MAKE US STRONGER. WE ARE DIFFERENT,<br />

BUT WE ARE EQUAL EVEN IF WE ARE LATE<br />

ENTRANTS TO THE PROFESSIONAL SPHERES.<br />

Anna Sparaco<br />

IN 2018 – WATCH THE WIHC-A SPACE –<br />

2 SOCIAL NETWORKING EVENTS AND<br />

SEVERAL WORKSHOPS ARE PLANNED.<br />

WE HOPE YOU ENJOY A GOOD REST<br />

AND HAVE A FESTIVE TIME OVER<br />

THIS DECEMBER AND COME BACK<br />

REFRESHED AND READY TO INCREASE<br />

THE TRACTION AND DEEPEN THE<br />

FOOTPRINT.<br />

Anna Sparaco: HPB practice, Wits Donald Gordon Medical Centre Correspondence: anna.sparaco@surgicalspecialist.co.za<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 18


FOCUS ON<br />

A WOMAN’S TALE:<br />

REFLECTING ON MY PERSONAL<br />

JOURNEY THROUGH A<br />

HEALTH SCIENCES<br />

ACADEMIC CAREER<br />

Beverley Kramer<br />

When I reflect on my life’s journey, as a mother, wife and academic,<br />

the town where I began life comes immediately to mind.<br />

Igrew up in a small East Rand town where mining<br />

was the lifeblood, and my family’s livelihood was<br />

linked to that as well. I am somewhat amazed<br />

that I made it out of that town and progressed in<br />

both thought and action to where I am today. I loved<br />

the town, my childhood there, the friendships that I<br />

developed; I could easily have remained there, lost<br />

forever in a timewarp. My story, however, is not really<br />

about my journey, but rather my mother’s journey, and<br />

how it affected my life.<br />

My mother began life in a mill on a stream in Lithuania,<br />

the daughter of a poor Jewish miller and his wife. She<br />

was one of five children growing up in a beautiful,<br />

but religiously intolerant country. At the age of 15, in<br />

order to escape the malevolent political and religious<br />

climate in Lithuania and the impending advance of<br />

the Nazis, she was sent by her parents on her own,<br />

by boat to <strong>South</strong> Africa. She joined two of her young<br />

siblings who had previously been sent to <strong>South</strong> Africa<br />

and settled here.<br />

The sudden separation from her parents was<br />

traumatic, the trip was long and frightening, but with<br />

her exuberance for life, she made friends on the boat,<br />

and this lessened her fear. My Mom’s schooling had<br />

been interrupted when she was sent to <strong>South</strong> Africa.<br />

She was never able to complete her education and<br />

regretted it all her life. Two years after reaching <strong>South</strong><br />

Africa she was married to<br />

my father, a kind and hardworking<br />

man who had also<br />

escaped from Lithuania<br />

but with his family, to find a<br />

better life in <strong>South</strong> Africa.<br />

My Father was much older<br />

than my Mother and worked<br />

extremely hard. He spent six<br />

and sometimes seven days<br />

Beverley Kramer<br />

a week in his concession<br />

store on the local mine to put<br />

food on the table. More importantly, my Mom wanted<br />

her three daughters to be well-educated, and thus<br />

we hardly ever saw my Dad as he laboured to scrape<br />

together every penny so that one day his daughters<br />

would be able to get a university education. My Mom<br />

cooked, baked and sewed for us.<br />

HER MAXIM WAS “I WILL SCRUB FLOORS<br />

TO GET YOU AN EDUCATION”. MY MOST<br />

VIVID MEMORY OF MY MOTHER’S<br />

THOUGHTS ON EDUCATION WAS:<br />

“STRIVE TO GET THE BEST EDUCATION<br />

THAT YOU CAN. PEOPLE CAN STRIP YOU<br />

OF EVERYTHING, BUT THEY CAN NEVER<br />

STRIP YOU OF YOUR EDUCATION.”<br />

19 *<br />

SOUTH AFRICAN WOMENS HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

I am sure this is a saying that reverberates with many<br />

even today. This left a lasting impression on me, but<br />

only later in life did I realize what this had meant in<br />

the context of her life.<br />

I was deeply saddened for my mother who had been<br />

stripped of her childhood, stripped of her family (she<br />

never found out what had become of her family<br />

who remained in Lithuania once the Nazis invaded),<br />

stripped of her home country and also stripped of<br />

the opportunity to complete her education. Her inner<br />

strength was something that shone through.<br />

My childhood was mostly uneventful, playing in<br />

the street with other children from a variety of<br />

backgrounds. They accepted that my religion was<br />

different to theirs and that I couldn’t play late on a<br />

Friday as my family celebrated the coming of the<br />

Sabbath. Children in those days were accepting and<br />

keen to share their differences. We walked back and<br />

forth to primary school, to the shops, to the homes of<br />

our friends, without the fear of being preyed on by<br />

the scourge of predators who target unsuspecting<br />

children today and remove from them the ability to<br />

have a relaxed childhood. We seldom wore shoes<br />

or had many toys to play with, but life was good. I<br />

remember spending school holidays reading or sitting<br />

on the fence watching cars go by.<br />

THIS IDYLLIC CHILDHOOD WAS<br />

HOWEVER SHATTERED IN MY LATTER<br />

PRIMARY SCHOOL YEARS WHEN I<br />

CAME INTO CONTACT WITH A TEACHER<br />

WHO HATED JEWS, OR PERHAPS HE<br />

HATED EVERYONE, AND JEWS WERE<br />

JUST WITHIN HIS REACH. THIS TEACHER,<br />

THOUGH I SHUDDER AT THE THOUGHT<br />

OF CALLING HIM A TEACHER, TOOK<br />

GREAT PRIDE IN REGULARLY MAKING<br />

ME STAND UP IN CLASS, TO POINT OUT<br />

TO THE STUDENTS THAT I WAS DIFFERENT,<br />

I WAS A JEW. I DIDN’T KNOW MUCH<br />

ABOUT RACISM IN THOSE EARLY YEARS,<br />

BUT I CERTAINLY SOON LEARNED THAT<br />

IT WAS ABHORRENT.<br />

High School in our small town was wonderful. It was<br />

great seeing friends each day. Being introduced to<br />

science was fascinating. I soon found that my love<br />

of books, which had started with reading at the age<br />

of three, had paid off. I had developed an excellent<br />

general knowledge and a yearning to learn. I tried to<br />

absorb as much information as I could, remembering<br />

from my mom that education was everything.<br />

Homework was not easy, as my Mom struggled to help<br />

me and once again, I felt saddened for her as she<br />

struggled with the English language and tried vainly<br />

to help us. My Dad was a whiz at mathematics, but<br />

we had to wait until late at night for his return if we<br />

needed help in that area.<br />

WHAT I SOON LEARNED FROM BOTH OF<br />

THEM THOUGH, WAS THAT THERE WAS<br />

NO SUCH THING AS “CAN’T”. I HAVE<br />

THUS TRIED EVERYTHING FROM ART TO<br />

ANATOMY, FROM PEWTER WORK TO<br />

POTTERY, IN THE REALIZATION THAT WHAT<br />

ISN’T KNOWN, CAN SOON BE LEARNED!<br />

It was customary in those days in our small town to see<br />

gangs of prisoners in chains working on the verges of<br />

the roads or even in the suburbs. These were prisoners<br />

who had been imprisoned for “minor” misdeeds or<br />

who had a short time left before release. All of these<br />

prisoners were black.<br />

My Mom would send us out with mugs of steaming<br />

coffee and liberally buttered bread, which was richly<br />

rewarded with huge smiles and even an occasional<br />

song. When I asked my Mother why she did this, she<br />

would tell me that we should always help those<br />

less fortunate than ourselves, that we should never<br />

discriminate against others no matter what the colour<br />

of their skin or their religion. She would tell me stories<br />

of the horrific discrimination against the Jews by the<br />

Nazis.<br />

SHE TAUGHT ME THE HORRORS OF RACIAL<br />

DISCRIMINATION, AND I LEARNED THAT<br />

IT WASN’T ONLY YOUR RELIGION THAT<br />

COULD CAUSE PEOPLE TO HATE YOU.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 20


FOCUS ON<br />

UNIVERSITY<br />

WAS HEAVEN<br />

With the intention of one day becoming a surgeon, I<br />

left high school and traveled to Johannesburg on the<br />

train to attend Wits University. This change was a total<br />

culture shock to me. The other 1 st year students in my<br />

class were confident, competent and they certainly<br />

knew a lot more about our topics and life than I did. I<br />

was scrutinized as I came into the class everyday……<br />

from the tips of my shoes to the last un-brushed hair<br />

on my head…….after all, dashing backwards and<br />

forwards between Johannesburg’s Park Station and<br />

Wits played havoc with one’s hair!<br />

I traveled on the train, back and forth to Johannesburg<br />

for seven years, in the cold and the heat, and learned<br />

that the train was a perfect place to study life. It was<br />

also where I learned that an umbrella was a girl’s best<br />

friend! Travelling home in the early evening after late<br />

laboratory sessions were slightly hazardous, as mean<br />

guys in long raincoats would often sit too close to one<br />

on the half empty carriages. A tap with a well-placed<br />

umbrella was all it took to get the “gentleman” in<br />

question to vacate the seat.<br />

UNIVERSITY WAS HEAVEN. I HAD<br />

NEVER BEEN EXPOSED TO SO<br />

MUCH INFORMATION, TO SO MANY<br />

INTRIGUING THINGS. THERE JUST<br />

WASN’T SUFFICIENT TIME TO TAKE IT<br />

ALL IN AND ALSO BE EXPOSED TO<br />

STUDENT LIFE. STILL NOT KNOWING<br />

WHETHER I WANTED TO DO MEDICINE<br />

OR SCIENCE, I WAS INTRODUCED TO<br />

THE MARVELS OF THE HUMAN BODY, TO<br />

ANATOMY.<br />

From my first day of dissection, i became fascinated<br />

by the body’s intricacies, by the incredible way<br />

in which it developed, how nerves and vessels<br />

managed to find their way to where they were going<br />

and did so almost always along the same pathways.<br />

Human anatomy and embryology became my<br />

fascination, and all thoughts of surgery vanished.<br />

Having completed my initial degree, i stayed on in<br />

the Wits Medical Department of Anatomy, first as a<br />

student and then as staff.<br />

My initial contact with anatomy in 1968 at the Wits<br />

Medical School on Hospital Hill, started me on a<br />

journey that is yet to be completed. From 1970 while<br />

doing my B.Sc Honours in anatomy, I was appointed<br />

as a Graduate Demonstrator and slowly rose through<br />

the academic ranks until I was appointed as Head<br />

of one Department (General Anatomy in the Wits<br />

Faculty of Dentistry) and then as Head of the Wits<br />

Department of Anatomy and Human Biology in the<br />

Faculty of <strong>Health</strong> Sciences (when the Faculties of<br />

Dentistry and Medicine amalgamated in 1996). This<br />

later became the School of Anatomical Sciences,<br />

which I initially chaired.<br />

Having been Head of Department and School for<br />

17 years, I stepped down to continue with research.<br />

However, always open to a challenge I applied<br />

for and was appointed Assistant Dean: Faculty<br />

of <strong>Health</strong> Sciences in 2008 and retired from this<br />

position at the end of 2016. I continue to teach in<br />

anatomy and undertake research. I am still involved<br />

with international anatomy and anatomists in my<br />

role as President of the International Federation of<br />

Associations of Anatomists.<br />

While all these positions sound wonderful and<br />

glamorous and a step up the academic ladder, they<br />

were paralleled by my even more precious normal life<br />

of being a wife, mother, and grandmother. Each of us<br />

who is a mother and wife will know of the toughness<br />

of the decisions we sometimes need to make, the<br />

challenges which arise when in a full-time position.<br />

AFTER THE BIRTH OF MY FIRST CHILD,<br />

MY STAUNCHEST SUPPORTER OF MY<br />

EDUCATION, MY MOTHER, ASKED<br />

WHETHER IT WASN’T TIME FOR ME TO<br />

GIVE UP WORK AND STAY AT HOME<br />

WITH MY BABIES!<br />

The 1970s were still a time when women had babies<br />

and stayed at home to look after them. I don’t think<br />

that my mother accepted easily that i wanted to work<br />

and be a mother! My years as an academic were<br />

mainly good (I love academic work and research,<br />

21 *<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

MY MOTHER’S WISDOM<br />

enjoy a challenge), often hard and also had some<br />

terrible moments. In my more senior years, I worked 13<br />

hours a day, six days a week. In order to build up the<br />

Department of General Anatomy, to ensure a smooth<br />

transition when the Dental and Medical Anatomy<br />

Departments were amalgamated and to develop<br />

the Research and Postgraduate portfolio in the Wits<br />

Faculty of <strong>Health</strong> Sciences, there was much to do.<br />

The wellbeing of individuals, while bringing two<br />

hugely different groups of staff together, needed<br />

careful management during the amalgamation<br />

of the Medical and Dental Anatomy Departments.<br />

Managing personality differences and a scientific<br />

breech was a harrowing experience when a fallout<br />

occurred between senior scientists in the<br />

School. Dealing with barriers from senior staff, when<br />

one is trying to grow an environment, was just not<br />

comprehensible. These and other challenging<br />

experiences often left me feeling isolated and alone.<br />

I was thankfully able to draw on my inner strength and<br />

optimism, and on the friendship of some wonderful,<br />

wise academics who offered advice and collegiality<br />

during these times. The lessons I had learned from my<br />

mother on racial and gender equality, on fairness and<br />

nurturing, sustained me during these difficult periods.<br />

AS WOMEN, WE TEND TO NURTURE,<br />

TO GROW, TO DEVELOP OTHERS. IF I<br />

SEE THAT SOMETHING NEEDS TO BE<br />

DONE, I GET UP AND DO IT. WERE<br />

OTHER ACADEMICS HELPFUL ALONG<br />

THE WAY? MANY STAFF WERE HELPFUL,<br />

SUPPORTIVE AND COLLEGIAL, BUT<br />

SOME WERE QUITE HORRID. MY<br />

FOCUS AND DRIVE WERE SOMETIMES<br />

CHALLENGED, AND AS I WAS A<br />

WOMAN, IT WAS EXPECTED THAT I<br />

WOULD BACK DOWN.<br />

Somewhere inside me the core of strength derived<br />

from my Mom and two female academics I had<br />

worked with, sustained me. There were a number<br />

of autocratic male academics for, or with, whom I<br />

worked, who couldn’t see academia as a “team”<br />

effort, but rather as a platform for their ego. This<br />

made academia not only hard but also infinitely more<br />

challenging! I was sometimes crucified for speaking<br />

out when I disagreed with what was happening, but<br />

know it was the correct thing to do. I hope that I leave<br />

this courage to “stand up and speak out “as a legacy<br />

to other women in academia.<br />

I MUST PAY TRIBUTE TO WONDERFUL<br />

MENTORS DURING MY ACADEMIC “LIFE”;<br />

KNOWLEDGEABLE AND WARM MEN AND<br />

WOMEN WHO SAW SOMETHING IN ME<br />

THAT THEY FELT WARRANTED NURTURING.<br />

FROM THEM, I LEARNED THE LOVE OF<br />

GROWING PEOPLE. I HAVE HAD GREAT<br />

JOY IN HAVING BEEN A ROLE MODEL<br />

TO SOME, A MENTOR TO MANY AND<br />

A TEACHER TO THOUSANDS. I LOVE<br />

“PAYING FORWARD” AND HAVE DERIVED<br />

ENORMOUS PLEASURE FROM SEEING THE<br />

WONDERFUL ACHIEVEMENTS OF MANY<br />

OF MY STUDENTS AND SOME OF THE<br />

YOUNG STAFF THAT I HAVE MENTORED.<br />

Over the last few years, I have found that academic<br />

collegiality has been changing (is this due to the<br />

pressure which academics experience?), barriers are<br />

being erected just because they can be, teamwork<br />

is not something to which everyone aspires, and<br />

bullying is on the increase, particularly bullying of<br />

senior women. I am particularly concerned about<br />

the latter. As one climbs the academic mountain, the<br />

higher the position, the more “power” is ascribed to<br />

the position. I believe that the higher the position, the<br />

greater is the responsibility to use that “power” wisely.<br />

This translates into building an academic environment<br />

that would benefit all, especially the next generation<br />

of academics.<br />

I REMAIN AN OPTIMIST, HAVE NEVER<br />

LEARNED WHEN TO STOP BANGING MY<br />

HEAD ON THE PROVERBIAL BRICK WALL<br />

AND THINK THAT I HAVE ACHIEVED AT<br />

LEAST HALF OF WHAT I WOULD HAVE<br />

LIKED TO ACHIEVE IN LIFE. MY GREATEST<br />

GIFTS HAVE BEEN MY WONDERFUL<br />

SONS AND MY GRANDCHILDREN, WHO<br />

I HOPE WILL, IN TURN, DERIVE FROM ME<br />

SOME OF MY MOTHER’S WISDOM.<br />

Professor Beverley Kramer: B.Sc.Honours, PhD, FAS (Hon), FAAA, Professor Emeritus, Director: Carnegie-Wits Alumni Diaspora<br />

Programme, President: International Federation of Associations of Anatomy (IFAA), School of Anatomical Sciences, Faculty of<br />

<strong>Health</strong> Sciences, University of the Witwatersrand, Johannesburg, <strong>South</strong> Africa Correspondence: Beverley.kramer@wits.ac.za<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 22


FOCUS ON<br />

SOUTH AFRICAN<br />

TAX AND DNA<br />

Jo-Anne Williams CA (SA)<br />

Just as DNA is a code and contains the key<br />

information for building and maintaining the<br />

organs in our body, similarly our tax legislation<br />

is comprised of various codes and like DNA<br />

you can use it to build and plan your decision around<br />

how tax affects you.<br />

BY GAINING A BASIC UNDERSTANDING<br />

OF THESE SA TAX DNA CODES WE<br />

CAN PLAN FOR TAX AND AVOID<br />

UNDUE STRESS AND PREVENTING<br />

DEVIATIONS FROM THE TAX CODE<br />

(NON-COMPLIANCE) THAT COULD<br />

CAUSE CANCEROUS CELLS, LIKE IN THE<br />

HUMAN BODY, BUT IN THE CASE OF THE<br />

TAX CODES THESE CANCEROUS CELLS<br />

PRESENT AS PENALTIES AND INTEREST.<br />

We shared some of the DNA of <strong>South</strong> <strong>African</strong> tax at<br />

our Tax Workshop, hosted by Women in <strong>Health</strong>care<br />

Africa.<br />

This article highlights some areas in the tax codes<br />

covered in the workshop.<br />

THE PROVISIONAL TAX CODE<br />

PROVISIONAL TAX, as with PAYE, forms part of the<br />

Income Tax Code structure and is important for all<br />

Companies and any individual who earns multiple<br />

sources of income or has not had sufficient PAYE<br />

withheld on a month to month basis. As with DNA<br />

each individual varies slightly from the other but the<br />

base tax code is mostly the same and just needs to<br />

include all the variable financial DNA information<br />

from a tax payer to function properly.<br />

Two important dates for when Provisional Tax would<br />

be paid is typically the last working day in August<br />

and February. The only time this will differ is if your<br />

company has a financial year end other than<br />

Jo-Anne Williams CA (SA)<br />

February. The tax paid for<br />

provisional tax should be<br />

based on an estimate of<br />

what your total Income<br />

Tax will be for that tax year<br />

and it is recommended<br />

you pay it on time, as well<br />

as the correct amount to<br />

avoid any cancerous results<br />

(Penalties and Interest!).<br />

THE INCOME TAX CODE<br />

For a company, the main code which applies to<br />

most companies is an Income Tax Rate of 28%. This is<br />

calculated after taking income (Revenue and other<br />

income) and deducting any valid business expenses.<br />

There is a separate tax code for Small Businesses, but<br />

as most services in healthcare are provided by the<br />

owner or Practitioner, not all these businesses will<br />

be able to apply this tax code to their business, as<br />

with DNA each individual is different and need to<br />

be assessed to see if their particular financial DNA<br />

(information) matches up to a certain income tax<br />

DNA code.<br />

FOR INDIVIDUALS, THE INCOME TAX<br />

DNA CODE IS MADE UP OF SEVERAL<br />

TAX PERCENTAGES TO APPLY TO AN<br />

INDIVIDUAL’S TAXABLE INCOME, DUE<br />

TO SOUTH AFRICA’S TIERED TAX RATE<br />

SYSTEM FOR INDIVIDUALS. AS SUCH<br />

A LOT MORE INFORMATION FROM A<br />

PERSON FINANCIAL DNA IS REQUIRED<br />

TO DETERMINE WHICH AND HOW THE<br />

SA INCOME TAX DNA CODE WOULD<br />

BE APPLIED TO THEM TO ALLOW FOR<br />

PROPER PLANNING AND AVOIDING<br />

ANY DEVIATION FROM THE SA INCOME<br />

TAX CODE.<br />

23 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

SA TAX<br />

DNA<br />

THE VAT CODE<br />

When looking at the VAT (Value Added Tax) Code,<br />

we discussed the various aspects around the VAT<br />

DNA code such as when it becomes mandatory to<br />

apply for VAT and how to apply this VAT DNA code in<br />

the structure of a medical practice. Although you can<br />

voluntarily apply the VAT code if you generate sales<br />

above R50,000 it becomes mandatory to register for VAT<br />

when your business is anticipating generating income<br />

of R1 million or more during any 12-month period.<br />

deduction of VAT charged by other business for goods<br />

or services rendered by them to your business, usually<br />

in a bi-monthly cycle.<br />

EMPLOYEE TAX CODES<br />

When hiring staff (including yourself in the case of<br />

a company), there are 3 main Employee Tax codes<br />

which will form part of the employees tax DNA for your<br />

practice, a monthly payment due to SARS by no later<br />

than the 7th of each month.<br />

IT MUST HOWEVER BE NOTED THAT<br />

IN APPLYING THIS VAT DNA CODE<br />

WITHIN YOUR BUSINESS THERE ARE<br />

A LOT OF COMPLEXITIES THAT NEED<br />

TO BE COMPLIED WITH, AND IT IS<br />

RECOMMEND TO HAVE A VAT CODE<br />

SPECIALIST, NAMELY AN ACCOUNTANT<br />

OR TAX PRACTITIONER, TO ASSIST IN<br />

PREVENTING DEVIATIONS FROM THE<br />

VAT CODE THAT COULD LEAD TO<br />

CANCEROUS RESULTS (PENALTIES AND<br />

INTEREST) DUE TO THE INCORRECT<br />

INFORMATION AND THE INCORRECT<br />

APPLICATION OF THIS VAT DNA TO THE<br />

CIRCUMSTANCES OR FINANCIAL DNA<br />

IN YOUR BUSINESS.<br />

A high-level view, the VAT (Value Added Tax) code is<br />

a rate of 14% which needs to be charged on sales/<br />

services rendered to patients, which is then paid<br />

over to the <strong>South</strong> <strong>African</strong> Revenue Services after the<br />

Jo-Anne Williams CA (SA): Co-Founder and Tax Director at Leading . Edge Accounting, specialising in accounting and tax for<br />

Small and Medium size businesses. Correspondence: Please contact the relevant sub-editor as well as cc the Editor-in-<br />

Chief for more information.<br />

THE FIRST OF THE EMPLOYEE TAX CODE IS PAYE<br />

(PAY AS YOU EARN), PAYE is calculated using the<br />

Individual Tax Rate table. It is determined by adding<br />

any salary and benefits (medical aid contributions,<br />

use of a motor vehicle, ect…) and then applying the<br />

rates from the Individual Tax code to the total of these<br />

amounts.<br />

THE SECOND EMPLOYEE TAX CODE IS UIF<br />

(UNEMPLOYMENT INSURANCE FUND), which<br />

is payable for anyone employed and working more<br />

than 24 hours a month. The rate applied is 2%, where<br />

1% is deducted from the employee’s salary and the<br />

other 1% is paid by the employer (limits are applied<br />

to the total amount that can be deducted for UIF).<br />

THE THIRD EMPLOYEE TAX CODE IS SDL (SKILLS<br />

DEVELOPMENT LEVY), this applies to businesses<br />

where the total salaries are anticipated to be more<br />

then R500 000 in the next 12 months. The application<br />

of the SDL code amounts to 1% being payable by<br />

the employer on the total amount in salaries paid<br />

per employee.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 24


FOCUS ON<br />

BE BOLD<br />

FOR CHANGE <strong>2017</strong><br />

Donne Botha<br />

I recently found myself reflecting on a voyage back in time thinking<br />

about the many wonderful women who have come before us and<br />

continue to make a difference and strive for the equality of all women.<br />

They have endured hardship and sacrifice<br />

for the freedom and upliftment of others,<br />

they have relentlessly pursued and acted<br />

with courage to overcome ethnic, religious,<br />

educational and gender prejudice. I couldn’t help<br />

but giggle as I traveled through the 60s – when<br />

females devoted their life to their husbands, children,<br />

and homemaking. The better you perform in your<br />

position, the cuter you were perceived. Now please<br />

don’t misunderstand me – being a devoted wife,<br />

mother and homemaker is very noble and something<br />

many of us strive to perfect in part, but it should be<br />

out of choice and not the expectation. Talking to<br />

many women today, it is clear that women desire<br />

different things in life and cannot be put in a box – the<br />

opportunity to reach life goals, whether it be enjoying<br />

or excelling at a hobby, choosing to accomplish a<br />

physical or spiritual purpose, attaining a promotion or<br />

high power position or devoting their time and life to<br />

their families and caring for loved ones.<br />

So luckily much has progressed in the workplace since<br />

the 1960s and women have far more choice since<br />

the beginning of time but how far have we really<br />

come? it is estimated that women make up 45% of<br />

the workforce yet hold only 9% of CEO positions and<br />

just 21% of leadership jobs globally.<br />

We know that globalization, building key capabilities,<br />

improved profits, customer engagement, high<br />

performance and fueling growth are just a few<br />

examples of corporate buzz words every time we<br />

walk into the boardroom and so if we are to achieve<br />

these goals, we need to recognize that gender<br />

diversity and inclusion matters and how we lead<br />

in this transformation will make all the difference to<br />

us and future generations. Studies have shown that<br />

companies with top quartile<br />

representation of women<br />

in executive positions<br />

perform significantly better<br />

financially than those with<br />

no women.<br />

It is this business issue and<br />

opportunity supported by<br />

Boston Scientific and being<br />

Donne Botha<br />

inspired by our daughters to<br />

be more and do more in creating equal opportunity<br />

for women in leadership, which led to the start of<br />

our women in leadership council in <strong>South</strong> Africa. Our<br />

goal is to create an inclusive environment to attract,<br />

develop and retain female talent at all levels and<br />

help them achieve their career best.<br />

We realize that the journey is not without barriers.<br />

Let’s be honest; we’re trying to change 4 million<br />

years of evolution! Finding and managing solutions<br />

to dealing with unconscious/conscious bias, work-life<br />

balance pressures, exposure to role models, gender<br />

readiness perceptions and networking opportunities<br />

are just a few examples of what we need to embrace,<br />

however if we seek to find the opportunity for every<br />

barrier and arm ourselves with the secrets of some of<br />

the most influential women of yesterday and today<br />

like courage, collaboration, embracing differences,<br />

perseverance, networking platforms and a passion<br />

for making a difference and self-belief, then nothing<br />

can stop us.<br />

Our message is simple – we are equal but different.<br />

We don’t want to be treated with special conditions<br />

and privilege; we want to be treated with fairness and<br />

equality based on our skills and capabilities.<br />

Donne Botha: Business Unit Manager, Urology & Pelvic <strong>Health</strong> at Boston Scientific. Correspondence: Please contact the<br />

relevant sub-editor as well as cc the Editor-in-Chief for more information.<br />

25 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

STOPPING THE<br />

BLUR<br />

Colleen Qvist<br />

I am sure that you have been on a train or car that is traveling so fast that<br />

all you can see out the window is a blur. The houses, buildings, people,<br />

animals and trees flow into each other.<br />

To many of us, this is what life feels like as we<br />

focus on a destination and the rest blurs into<br />

a grey streak.<br />

We have become so goal orientated. Our days<br />

and nights are taken up with the constant quest for<br />

success. The promotion, buying the new car, reaching<br />

a specific salary or weight, getting the kids through<br />

Grade 4 or 8 or 12 or even the number of Facebook<br />

friends all occupy our minds.<br />

We are even focused on getting to the end of the<br />

year so that we can turn over that last page and start<br />

the next year.<br />

WE ARE SO CAUGHT UP IN THE<br />

DESTINATION AND THE GOAL THOUGH,<br />

THAT OUR TODAY AND THE MAGIC<br />

MOMENTS IN THE NOW ARE LOST.<br />

WE CANNOT GET THEM BACK, AND I<br />

WONDER IF THIS IS WHY IT FEELS LIKE<br />

TIME IS RUSHING PAST SO QUICKLY? WE<br />

ARE SITTING IN OUR “TRAINS” NOT EVEN<br />

AWARE OF THE BLUR AS WE FOCUS ON<br />

THE DESTINATION.<br />

If all of this focus is making you feel empty and you<br />

would like to stop to smell the coffee and to drink it<br />

with the people who matter, I would like to suggest<br />

two powerful interventions.<br />

Colleen Qvist<br />

MEDITATION<br />

As soon as I mention<br />

meditation to my coaching<br />

clients, they automatically<br />

reply that they do not know<br />

how to do meditation and I<br />

am sure they are picturing<br />

sitting on a mat in a yoga<br />

pose. I am also told that<br />

they cannot do silence or<br />

that they do not know how<br />

to empty their minds.<br />

WE ARE DEFINED BY THE RULES OR OUR<br />

PERCEPTION OF THE RULES.<br />

A meditation programme that has made a massive<br />

difference in my life is Insight Timer. My daughter<br />

introduced me to the app at the end of last year,<br />

and it is downloaded on my cell phone. It has a<br />

whole array of different types of meditations of<br />

varying lengths, guided, silence, musical, nature and<br />

I have enjoyed choosing one, and if I do not like that<br />

particular one, I stop it and find a new one.<br />

I have seen the difference in me (and my daughter)<br />

as I have meditated most days. I have been aware<br />

that my thoughts and the shopping list do not<br />

necessarily leave my thoughts. Instead, I picture a<br />

river, and I allow those thoughts to float on past.<br />

27 *<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

I WOULD LIKE TO ENCOURAGE YOU TO<br />

EXPERIMENT WITH MEDITATION AND<br />

TO DO WHAT MAKES YOU FEEL GOOD.<br />

LET’S SKIP THE MANUAL WITH THE 100<br />

WAYS TO DO IT SOMEONE ELSE’S WAY.<br />

GRATITUDE<br />

My home has a gratitude jar in the kitchen. It is a large<br />

see-through jar and next to it are coloured pieces of<br />

paper and a pen. We write something we are grateful<br />

for and pop it into the jar. Even my daughter, who<br />

does not live here during the week comes home on<br />

weekends to fill in her gratitude slips.<br />

On 31 December we gather as a family and unpack<br />

the jar and read what we have written. You will be<br />

amazed at how many pieces of paper can fit into a<br />

jar. It is a reminder of all we had to be grateful for and<br />

that the year was indeed filled with blessings. Have<br />

you noticed how people tend to decide by the end<br />

of the year that the year was BAD and that it is time<br />

for a new one? The sad thing is the following year will<br />

also be BAD, and they will need another one.<br />

WE HAVE PLACED THE OLD GRATITUDE<br />

JAR FROM THE PREVIOUS YEAR IN THE<br />

LOUNGE, AND IT IS AN ORNAMENT<br />

WITH THE PURPOSE TO REMIND US<br />

THAT GRATITUDE IS AN AMAZING<br />

WAY TO ATTRACT MORE THINGS TO BE<br />

GRATEFUL FOR. IN THE QUEST FOR THE<br />

DESTINATION, WE SO OFTEN FORGET<br />

WHAT WE HAVE ALREADY, AND I AM<br />

HUMBLED BY THE SAYING “BE MINDFUL<br />

THAT WHAT YOU ALREADY HAVE, OTHER<br />

PEOPLE ARE PRAYING FOR.”<br />

Making a lasting impact in our lives depends on us<br />

introducing new habits, and this takes repetition<br />

and reinforcement. Do send me the pictures of your<br />

gratitude jar and share stories of how meditation<br />

helps you. You may have other<br />

methods to help you slow down to<br />

notice the magical moments, and<br />

you are welcome to share these too.<br />

Colleen Qvist: Business and Personal<br />

Coach, Facilitator and Speaker,<br />

Founder of CQ Consulting and<br />

The Pink Diamond Club.<br />

Gauteng Chair for COMENSA<br />

and serves on the Women in<br />

<strong>Health</strong>care Africa Exco.<br />

Correspondence: colleen@cqconsulting.co.za<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 28


FOCUS ON<br />

29 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

HOW SOPHROLOGY:<br />

HELPS PREGNANCY<br />

A WOMAN’S JOURNEY<br />

BEFORE, DURING & AFTER<br />

Ishana Maharaj<br />

OBSTETRICS & GYNAECOLOGY<br />

Many women have a deep need or<br />

sometimes a secret wish to start a family.<br />

It’s a magical moment to become a<br />

loving mother and experience the pure<br />

unconditional love of her own baby.<br />

However for some women, falling pregnant has its<br />

challenges in today’s demanding environment,<br />

largely due to career pressures combined with<br />

the rigors of hectic daily lives. Adding workplace<br />

obstacles, it becomes a challenge for women to<br />

cope.<br />

SOPHROLOGY IS A SIMPLE, HOLISTIC<br />

APPROACH AIMED AT BRINGING THE<br />

MIND, BODY & SPIRIT INTO HARMONY<br />

Comprising of effective exercises, breathing<br />

techniques, visualization, bits of meditation and many<br />

additional techniques, this leads to optimal health<br />

and wellbeing. Sophrology is beneficial to all stages<br />

of pregnancy (i.e. Pre-Natal, Delivery & Post-Natal). It<br />

can be done in various sitting positions, standing or<br />

lying down if fatigued.<br />

PRE-NATAL STAGE<br />

“I am really trying to fall pregnant …”<br />

Ishana Maharaj<br />

The elements of stress,<br />

burnout, tension and anxiety<br />

together with an unhealthy<br />

diet, impacts the body and<br />

results in a less desirable<br />

lifestyle. When the body<br />

endures this long-term<br />

stress, complications may<br />

arise, and this does not help<br />

women who want to fall<br />

pregnant.<br />

But there’s hope, as Sophrology comes to the rescue.<br />

There could be various medical reasons why a woman<br />

has difficulties in falling pregnant. Once identified,<br />

solutions or options could be recommended by a<br />

doctor.<br />

Whatever solution or changes are required to reach<br />

this goal, Sophrology helps in the following ways:<br />

• Prepares the body for pregnancy – i.e. physically,<br />

mentally and spiritually<br />

• Releases stress, tension & anxiety from the body<br />

• Supports you through the possible ups and downs<br />

of IVF and helps you build resilience<br />

• Harmonizes/Activates/Stimulates all cells, organs,<br />

bones, muscles, glands and systems of the body<br />

• Keeps you in a calm, peaceful, relaxed state<br />

• Exercises are customized to focus on an individual’s<br />

needs<br />

• Enhances & improves ALL systems of the body:<br />

i.e. Reproductive; Immune/Lymphatic; Endocrine;<br />

Digestive; Nervous; Cardiovascular; Renal &<br />

Muscular Systems<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 30


FOCUS ON<br />

SOPHROLOGY COMES TO THE RESCUE<br />

DELIVERY STAGE<br />

You will feel prepared for any type of situation<br />

that might emerge on the day of the birth, and<br />

feel equipped to deal with difficult situations<br />

• Creating a better connection with baby in the<br />

womb through practicing visualization exercises<br />

• Supporting the digestive system, especially during<br />

heartburn, constipation or cramping<br />

• Assisting with & managing pain endurance<br />

• Staying focused on yourself & baby and<br />

embracing each step of pregnancy consciously<br />

“I am pregnant! However, I am anxious<br />

and scared…”<br />

Whether it’s your first or fourth baby to be born, each<br />

woman’s journey is unique. Some women worry or<br />

panic about whether they are able:<br />

• to carry to full term of pregnancy,<br />

• scared of the birth procedure,<br />

• Helping to visualize your baby’s journey into the<br />

world<br />

• Boosting your confidence and taking the time to<br />

integrate the changes you are going through<br />

• Helping to remove your fears<br />

POST-NATAL STAGE<br />

• or how to cope with certain health complications<br />

during their pregnancy<br />

During the 9 months of pregnancy, a woman comes<br />

to terms with becoming a mother. In the real world,<br />

there is never enough time to look after ourselves.<br />

We need to be aware of the adverse effects of stress<br />

on the body.<br />

OUR EXTERNAL APPEARANCE CAN<br />

ALSO BE A SOURCE OF WORRY.<br />

SOPHROLOGY ALLOWS PREGNANT<br />

WOMEN TO ACCEPT AND EMBRACE<br />

THIS SPECIAL TIME OF LIFE AND FIND<br />

IT MEANINGFUL RATHER THAN SCARY.<br />

IT ENABLES A PREGNANT WOMAN’S<br />

FOCUS TO SHIFT FROM THE WORRY<br />

ABOUT HER SHAPE TO FEELING<br />

EMPOWERED BY THE LIFE WITHIN.<br />

WE MUST NOT FORGET THE ROLE<br />

OF FATHERS AS WELL, WHO MAY BE<br />

EXPERIENCING STRESS AND ANXIETY<br />

DURING THEIR PARTNER’S PREGNANCY.<br />

Sophrology supports them through this process<br />

of transition, learning about their partner’s body<br />

changes and welcoming the arrival of the baby.<br />

Sophrology helps by:<br />

• Creating a more relaxed pregnancy & positive<br />

delivery – by doing various breathing techniques.<br />

“Motherhood …I am always tired,<br />

experience fatigue and<br />

sometimes feel depressed …”<br />

Giving birth or being a mum can be the most<br />

phenomenal and wonderful gift in life, however, your<br />

body has been through a huge physiological roller<br />

coaster and it needs time to recover. Many women<br />

feel tired, overwhelmed and frustrated for they cannot<br />

cope as well as they did before they had children.<br />

Sophrology helps you achieve that deep state of<br />

relaxation which is called “sophroliminal state”. This<br />

occurs when the alpha brain waves kick in to provide<br />

a sense of well-being.<br />

Time is precious, especially when you have to establish<br />

a new routine with baby. Sophrology offers simple and<br />

31 *<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

effective techniques that can be practiced regularly<br />

for 20 min at any time, in the comfort of your home.<br />

The exercises offer immediate relief. Sophrology can<br />

help you to:<br />

• Improve & speed up your recovery process after<br />

birth<br />

• Balance your emotions and mood swings related<br />

to hormonal changes<br />

• Accept the transition and improving your quality<br />

of life<br />

• Sleep better so that you feel more energized and<br />

alert<br />

• Deal positively with family, expectations, beliefs<br />

etc.<br />

• Bond with your baby and feel motivated/positive<br />

in your new role<br />

IN CONTINENTAL EUROPE DOCTORS<br />

RECOMMEND SOPHROLOGY AS AN<br />

EFFECTIVE RELAXATION AND SELF-<br />

DEVELOPMENT TECHNIQUE TO NOTABLY<br />

HELP DEAL WITH PREGNANCY, PREPARE<br />

FOR BIRTH, DEAL WITH ANXIETIES AND<br />

LACK OF SLEEP.<br />

IT CAN HELP YOU PREPARE FOR BIRTH<br />

BY ENABLING YOU TO ACCESS YOUR<br />

INNER RESOURCES, REINFORCING<br />

CONFIDENCE AND POSITIVITY.<br />

SOPHROLOGY CAN HELP YOU EMBRACE<br />

THE EXPERIENCE OF PREGNANCY, BIRTH<br />

AND MOTHERHOOD ACCORDING TO<br />

YOUR PERSONAL VALUES.<br />

Ishana Maharaj: Sophrology Practitioner - Having worked in<br />

the corporate world for over 18 years, I resigned as a Project<br />

Manager to relocate to Switzerland with my family, for a few<br />

years. During my time in Geneva, I discovered Sophrology,<br />

and was fascinated by its history, and widespread adoption<br />

in Switzerland, France, Spain and the UK over the last 55<br />

years. Having studied Sophrology at a leading institution in<br />

Geneva, Switzerland, I personally experienced the benefits<br />

of this journey. Returning to my home in <strong>South</strong> Africa as a<br />

Sophrology Practitioner, being a Mum of 3 children (son-<br />

17yrs & twin girls 10yrs of age), I felt blessed with a “gift”.<br />

A special gift to share with people of <strong>South</strong> Africa. My<br />

ultimate passion is to create an awareness, help, support,<br />

share my knowledge and experiences of this phenomenal<br />

wellness technique, with people. As the first Sophrologist in<br />

Johannesburg, my practice resides in Eagle Canyon Business<br />

Centre, Eagle Canyon Estate, Honeydew.<br />

Correspondence: ishana@sophrology.co.za;<br />

www.sophrology.co.za; Cell: 0827994311.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong> * 53<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 32


FOCUS ON<br />

FAT<br />

G R A F T I N G<br />

35 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

THE ROLE OF<br />

FAT GRAFTING<br />

IN AESTHETIC SURGERY<br />

Marisse Venter<br />

AESTHETICS & RECONSTRUCTION<br />

The concept of transferring fat from one area of the body to another has<br />

been around for a very long time.<br />

Living fat tissue is harvested from one area of<br />

the body, purified and transferred to another<br />

to add volume. Ideally, the fat is harvested by<br />

liposuction in an area of unwanted or excess,<br />

e.g., the belly, love handles or thighs, it is then carefully<br />

injected into an area where the main aim is to correct<br />

a volume deficit.<br />

Fat grafting is used in breast surgery and facial<br />

rejuvenation in many ways. Volume replacement<br />

and correction of contour deformities can be used<br />

for breast augmentation, partial breast resection,<br />

implant-related contour deformities, radiation injury,<br />

scar management and facial rejuvenation, in the<br />

same way “Polly-filler” is used to smooth dents and<br />

irregularities.<br />

Recent literature suggests that fat has numerous<br />

added advantages. Fat is rich in pro-inflammatory<br />

cytokines, growth factors, stem-cells and has multiple<br />

cellular functions.<br />

THUS THE BENEFITS OF FAT STRETCH FAR<br />

BEYOND WHAT THE NAKED EYE MAY SEE<br />

AFTER THE PHYSICAL IMPROVEMENT IS<br />

NOTICED. OFTEN THE SURGEON AND<br />

PATIENT COMMENT ON AN IMPROVED<br />

SKIN TEXTURE IN THE AREA WHERE FAT<br />

GRAFTING WAS DONE.<br />

Marisse Venter<br />

The effect of adipose-derived<br />

stem cells on breast tissue in<br />

patients with previous breast<br />

cancer is not entirely known.<br />

The literature has established<br />

that fat grafting does not<br />

interfere with the ability to<br />

detect malignant changes<br />

in breast tissue nor do the<br />

stem cells cause cancer cells<br />

to proliferate or form new<br />

cancers.<br />

THE EXACT EFFECTS OF FAT GRAFTING<br />

WILL ONLY BE KNOWN OVER SOME<br />

YEARS TO COME. WE HAVE SAFELY BEEN<br />

PERFORMING FAT GRAFTING OVER THE<br />

PAST TEN YEARS WITH NO ADVERSE<br />

EFFECTS.<br />

According to the American Association of Plastic<br />

Surgeons: “The existing evidence suggests<br />

autologous fat grafting as an effective option in<br />

breast reconstruction following mastectomy while<br />

demonstrating moderate to significant aesthetic<br />

improvement. Also, the available evidence also<br />

cites autologous fat grafting as a useful modality<br />

for alleviating post mastectomy pain syndrome.<br />

Furthermore, the evidence suggests autologous fat<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 36


FOCUS ON<br />

grafting as a viable option for improving the quality<br />

of irradiated skin present in the setting of breast<br />

reconstruction.”<br />

Usually, 40% of the injected fat cells may not survive.<br />

Thus additional fat grafting may be required<br />

several months later. However, the 60 -70% of the fat<br />

transplants that do survive will be permanent. It is<br />

not uncommon for a patient to receive multiple fat<br />

grafting procedures.<br />

Fat grafting is most commonly performed in theater<br />

under general anesthesia, and occasionally may be<br />

performed as an outpatient procedure in the rooms.<br />

THE ADVANTAGES OF FAT GRAFTING ARE:<br />

• using your own tissue<br />

• fat is removed from an unwanted area<br />

• both the liposuction and the fat injections are<br />

done with local anesthetic<br />

• It is not a significant surgical procedure and<br />

involves only a few days recovery in most cases<br />

• many women report that a fat-graft reconstructed<br />

breast has sensation and feels soft, much like a<br />

natural, unreconstructed breast<br />

• There is an improvement in the overlying skin<br />

texture, skin quality, and subcutaneous<br />

component.<br />

THE DISADVANTAGES OF FAT GRAFTING ARE:<br />

• No significant clinical studies with long-term follow<br />

up have been done on fat grafting, but small<br />

studies report good results, i.e. there is a currently<br />

ten-year data out.<br />

• The injected fat may be reabsorbed by the body<br />

you may lose some volume over time<br />

• Some of the fat injected into the breast area may<br />

die, which is called “necrosis” (symptoms of<br />

necrosis may include pain and bleeding, the skin<br />

turning dark blue or black, numbness, fever, and<br />

sores that ooze a bad-smelling discharge or pus)<br />

• Contour deformities may occur at the liposuction<br />

site and have all the complications associated<br />

with liposuction<br />

• Asymmetry and irregularity between the sides<br />

lip-filled<br />

• Prolonged swelling & bruising in facial area<br />

• 1% incidents of blindness have been reported<br />

which is permanent<br />

THE PROCEDURE<br />

This is mostly performed under a general anesthetic,<br />

although occasionally the procedure may be<br />

performed under local anesthetic. The reconstructive<br />

surgeon may mark the appropriate areas for<br />

liposuction before the procedure. Small (5mm)<br />

access incisions are made for liposuction. These<br />

small incisions are closed by absorbable suture<br />

material. Liposuction may be done either from the<br />

lower abdomen, thighs, flanks or buttocks. The fat<br />

is prepared and injected into the desired area by<br />

small, precise injections. The liposuction area may be<br />

strapped post operatively to maintain compression.<br />

One would have to stay in the hospital for a day post<br />

surgery. Antibiotics and pain tables will be given<br />

to take home. Recovering from fat filling is mostly<br />

swift and uneventful as an isolated fat fill is a minor<br />

procedure. There may be some oozing of clear fluids<br />

from the liposuction areas.<br />

WHAT YOU SHOULD KNOW<br />

The most common complications seen in fat grafting<br />

is prolonged swelling and bruising at the injection<br />

site. The swelling is less of a problem in the breast<br />

but may cause significant distress if facial swelling<br />

remains for a long time.<br />

The amount of fat that survives is unpredictable. The<br />

current estimation is that 40% of the fat volume will be<br />

lost. The volume deficit depends on numerous, not as<br />

yet openly identifiable factors, e.g. increase metabolic<br />

rate, medication, etc.<br />

ANOTHER, PERHAPS LESS KNOWN<br />

COMPLICATION OF FAT GRAFTING IS<br />

THE TENDENCY OF THE FAT VOLUME TO<br />

INCREASE AS BODY WEIGHT INCREASES.<br />

ONCE AGAIN THE DIFFICULTY IS<br />

MOST TROUBLESOME IN THE FACE AS<br />

LOCALIZED FAT POCKETS MAY ARISE<br />

RESULTING IN, E.G. BAGS UNDER THE<br />

EYES. THE FAT COLLECTIONS CAN<br />

BE MANAGED BY FAT REMOVAL OR<br />

LIPODISSOLVE.<br />

As the use of fat grafting is increasing, numerous<br />

added effects of fat grafting are becoming evident.<br />

Fat grafting has shown to decrease fine lines and<br />

wrinkles, improve skin texture, lighten pigmentation<br />

and forms new collagen and elastin, thus delaying<br />

the aging process.<br />

DR MARISSE VENTER: Plastic and Reconstructive Surgeon at Netcare Milpark Hospital. She has a special interest in breast<br />

reconstruction and cosmetic surgery. Correspondence: dr.mventer@gmail.com<br />

37 *<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

THE LOW DOWN<br />

HEALTH AND LIFESTYLE<br />

Inge Kriel<br />

VACCINATION RATES HAVE DECREASED IN RECENT YEARS,<br />

LARGELY IN RESPONSE TO THE ANTI-VAXXER MOVEMENT.<br />

accination rates have decreased in recent<br />

years, largely in response to the anti-vaxxer<br />

movement. Social media has contributed<br />

to fear mongering in the general<br />

population, with patients reporting vaccine-related<br />

side-effects on a variety of social media platforms<br />

and encouraging other parents not to vaccinate<br />

their children.<br />

DR ANDREW WAKEFIELD, THE INFAMOUS<br />

MEDICAL GASTRO-ENTEROLOGIST<br />

WHO PUBLISHED HIS FINDINGS IN THE<br />

THE LANCET THAT THE MMR VACCINE<br />

IS RELATED TO AUTISM, HAS SINCE<br />

BEEN STRUCK OFF THE ROLL AS HIS<br />

METHODOLOGY WAS QUESTIONABLE<br />

AND HE DID NOT DECLARE A POTENTIAL<br />

CONFLICT OF INTEREST. HIS ARTICLE<br />

WAS WITHDRAWN FROM THE JOURNAL<br />

AS HE WAS WIDELY DISCREDITED.<br />

Unfortunately, the damage has been done – his article<br />

has fuelled the anti-vaxxer movement to the point<br />

that the MMR vaccine is no longer in production in<br />

some areas due to lack of demand. There have been<br />

recent outbreaks of measles and diphtheria in <strong>South</strong><br />

Africa, most likely due to poor uptake of vaccinations.<br />

Patients place their trust in health care professionals<br />

– they trust us to guide them in making decisions<br />

regarding their health. However, when one of our own<br />

publish their unverified findings in an eminent medical<br />

journal, patients are left bewildered and confused as<br />

to whom to trust.<br />

If a medical doctor is telling<br />

them not to vaccinate, then<br />

they trust that it would be in<br />

their best interests to follow<br />

this advice.<br />

Furthermore, patients have<br />

access to scientific journals<br />

without the requisite<br />

training in interpretation of<br />

Inge Kriel<br />

statistics. This creates a very<br />

dangerous situation in which patients make ill-advised<br />

decisions based on dodgy statistics.<br />

All health care practitioners, whether generalists or<br />

specialists, should be doing more to promote uptake<br />

of vaccinations. Vaccinations should be discussed at<br />

every consultation. A balanced approach should be<br />

taken when discussing vaccines – the benefits and the<br />

potential adverse effects both deserve equal attention.<br />

SO WHAT SHOULD WE BE FOCUSING ON<br />

DURING CONSULTATIONS WITH REGARDS TO<br />

VACCINATIONS?<br />

Firstly, we should be reassuring patients that multiple<br />

large randomised controlled trials have failed to<br />

demonstrate a causal relationship between the MMR<br />

vaccine and autism.<br />

Secondly, while we are obliged to discuss potential<br />

side-effects of vaccines, we should spend an equal<br />

amount of time discussing the potential negative<br />

consequences of not being vaccinated.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 38


FOCUS ON<br />

I WAS IN ICU FOR A WEEK AFTER<br />

CONTRACTING MENINGOCOCCAL<br />

SEPTICAEMIA DURING MY DAYS AS A<br />

MEDICAL STUDENT. MENINGOCOCCAL<br />

SEPTICAEMIA HAS A MORTALITY OF<br />

100% IF LEFT UNTREATED, WITH A<br />

MORTALITY RATE APPROACHING 50%<br />

EVEN IF APPROPRIATE TREATMENT<br />

IS TIMEOUSLY COMMENCED. THE<br />

INFECTIOUS DISEASE SPECIALIST<br />

MANAGING MY CASE TOLD MY FAMILY<br />

THAT ONLY TWO OUT OF THE FIFTY<br />

PATIENTS WITH MENINGOCOCCAL<br />

SEPTICAEMIA THAT HE HAD TREATED,<br />

SURVIVED. I WAS ONE OF THEM.<br />

Meningococcal septicaemia is a vaccine-preventable<br />

illness. Menactra, the vaccine recently launched,<br />

protects against four of the most common strains of<br />

Neisseria meningitides. However, when I did a quick<br />

survey amongst parents at my son’s day-care, only<br />

one or two parents even knew that Menactra existed.<br />

FURTHERMORE, I HAVE NOTICED IN<br />

GENERAL PRACTICE THAT PATIENTS (AS<br />

WELL AS HEALTH CARE PROFESSIONALS)<br />

ARE MISINFORMED ABOUT HOW AND<br />

WHEN VACCINATIONS CAN BE GIVEN.<br />

Vaccines should be delayed in moderate to severe<br />

acute infectious conditions (with or without fever),<br />

but there is no contraindication to vaccination in the<br />

presence of mild illness (even with fever). Mild acute<br />

illnesses include upper respiratory tract infections,<br />

colds, otitis media and mild diarrhoea. Delay in<br />

vaccination of patients with mild illness may hamper<br />

vaccination uptake.<br />

Other conditions incorrectly perceived as vaccination<br />

contra-indications include: previous erythema/<br />

oedema at injection site or low-grade/moderate<br />

fever after previous immunisation, current antibiotic<br />

therapy, and history of non-vaccine allergies.<br />

Administration of the varicella vaccine is not contraindicated<br />

for individuals who have a family member<br />

or household contact with immunodeficiency, or in<br />

the setting of HIV infection where the patient only has<br />

mild symptoms. Hepatitis B can safely be given during<br />

pregnancy and in the setting of auto-immune disease.<br />

Confusion arises with regards to co-administration<br />

of vaccines. Vaccinations may be inappropriately<br />

delayed due to lack of knowledge regarding which<br />

vaccinations can safely be given at the same visit.<br />

As a general rule, most vaccines can safely be coadministered.<br />

An exception to this rule is that the<br />

pneumococcal vaccine (PCV13) should not coadministered<br />

with Menactra in patients with functional<br />

or anatomic asplenia. PCV13/DTP should not be coadministered<br />

with influenza vaccination as there is<br />

an increased risk of febrile seizures. Live parenteral<br />

vaccines (MMR, MMRV, Varicella, Zoster, and yellow<br />

fever) may be administered simultaneously. If not<br />

administered on the same day, they should be given<br />

at least four weeks apart in order to eliminate potential<br />

interference (the first vaccine may interfere with the<br />

antibody response of the second vaccine). Every<br />

opportunity should be taken to ensure simultaneous<br />

administration of vaccinations, especially in children,<br />

as this increases the likelihood that patients will be<br />

fully immunised according to schedule.<br />

Combination vaccinations are preferred over single<br />

component vaccines. One notable exception is the<br />

MMRV vaccine in children 12 to 47 months of age. In<br />

this subset, simultaneous administration of the single<br />

component vaccinations is preferred because of the<br />

increased risk of febrile convulsions with the MMRV<br />

vaccine. HPV vaccines are recommended in girls<br />

and boys from the age of 9. These vaccines confer<br />

protection against the oncological HPV serotypes<br />

(namely 6, 11, 16, 18), and help to prevent cervical,<br />

vaginal, vulval and anal cancers, and genital warts.<br />

HPV infection may also play a role in throat and<br />

penile cancers.<br />

Women planning to fall pregnant should receive the<br />

MMR vaccine (if immunity is insufficient), one or two<br />

months before falling pregnant, as this vaccine is<br />

not safe to administer during pregnancy. Ante-natal<br />

Rubella is particularly dangerous to the foetus – it<br />

may result in serious birth defects or even pregnancy<br />

loss. Inactivated influenza vaccine can safely be<br />

administered during pregnancy. This is particularly<br />

important as pregnant patients are at an increased<br />

risk of influenza-related complications.<br />

Patients also need to be made aware of the concept<br />

of herd immunity. Live-attenuated vaccinations are<br />

contra-indicated in severely immunocompromised<br />

patients. These patients rely on herd immunity to<br />

protect them from communicable diseases, but if<br />

vaccination rates are not maintained in a patient<br />

population, then these individuals are at risk. The antivaxxer<br />

movement has compromised herd immunity in<br />

certain areas, due to inadequate vaccination rates.<br />

The benefit of vaccination far outweighs the<br />

risks. <strong>Health</strong> care professionals should take every<br />

opportunity to vaccinate individuals, and vaccinations<br />

should not be delayed unless clear contra-indications<br />

exist. We need to do more to educate patients on<br />

the dangers of not vaccinating, in order to improve<br />

herd immunity and eradicate vaccine-preventable<br />

contagious diseases, and ultimately protect those<br />

individuals who are unable to receive vaccinations<br />

due to medical reasons.<br />

Inge Kriel: Oncology Care Physician, Milpark Breast Care Centre of Excellence. Correspondence: ingekriel84@gmail.com<br />

39 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

IZZY’S<br />

STORY<br />

Kyara Bergstrom<br />

The anti-vaxxer movement has upset me so much. People often get<br />

shocked at my reaction until they hear about my little girl Isabella, and<br />

then they understand why.<br />

Izzy has been ill since the day she was born. It<br />

was only at the age of 3 that she was diagnosed<br />

with Common Variable Immune Deficiency<br />

(CVID). Like most people I hadn’t heard about<br />

this. Let’s be honest - when most people think of<br />

immune system problems, we think of cancer and<br />

chemotherapy, or HIV. There are many more primary<br />

immune deficiencies. Think of the movie “Boy in the<br />

Bubble”.<br />

Izzy can’t fight infections on her own. She has a<br />

T-Cell defect, as well as a mannose binding lectin<br />

deficiency. One of the ways doctors diagnosed her is<br />

that she had no antibodies from her vaccines. I have<br />

vaccinated my kids with every single vaccine. I never<br />

used to believe in the flu vaccine until I saw my eldest<br />

get H1N1 (swine flu) when it was making the rounds.<br />

Have you ever seen your child crying and screaming<br />

in pain? You can’t comfort her because her body<br />

hurts so badly and she has a fever so high you don’t<br />

want to leave her for a minute in case she has a<br />

febrile seizure? Well that’s the year I started believing<br />

in the flu vaccine and now we all get vaccinated<br />

every year to protect ourselves, as well to protect Izzy<br />

as much as we can.<br />

Izzy relies on something called immunoglobins.<br />

When people donate blood, they only think of red<br />

blood cells and plasma for<br />

accident victims, surgery,<br />

cancer etc. What they don’t<br />

normally think about is the<br />

immunoglobins from these<br />

transfusions that are taken<br />

and given to people like Izzy.<br />

It takes a lot of transfusions<br />

to make one treatment<br />

and doesn’t rely on blood<br />

type. So I’m always on a<br />

Kyara Bergstrom<br />

campaign to get people to<br />

donate blood. She gets these immunoglobins every<br />

four weeks. Without this she will not be able to fight<br />

the infections like the rest of us. Even when she gets<br />

sick she’s placed on adult dosages of antibiotics and<br />

most of the time she has to be hospitalised when she’s<br />

sick.<br />

SO THIS BRINGS ME BACK TO VACCINES.<br />

PEOPLE OFTEN ASK ME “HOW IS MY<br />

UNVACCINATED CHILD DANGEROUS<br />

TO YOUR VACCINATED CHILD?”.<br />

I UNDERSTAND HOW THIS CAN BE<br />

CONFUSING AS MOST PEOPLE DON’T<br />

UNDERSTAND THE CONCEPT OF HERD<br />

IMMUNITY.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 40


FOCUS ON<br />

HERD<br />

IMMUNITY<br />

IF ENOUGH PEOPLE ARE VACCINATED,<br />

THEN THEY PROTECT THE PEOPLE THAT<br />

ARE UNABLE TO BE VACCINATED.<br />

IT’S NOT ONLY PEOPLE LIKE IZZY<br />

WHO RELY ON HERD IMMUNITY.<br />

ADULTS AND CHILDREN RECEIVING<br />

CANCER TREATMENT, PEOPLE ON<br />

IMMUNE SUPPRESSANTS FOR ORGAN<br />

TRANSPLANTS, HIV POSITIVE PATIENTS,<br />

AND PATIENTS WITH AUTO-IMMUNE<br />

DISEASES ALSO RELY ON HERD<br />

IMMUNITY. THEY DON’T HAVE A CHOICE<br />

AND THEY RELY ON OTHERS TO BE<br />

VACCINATED. HERD IMMUNITY ALSO<br />

PROTECTS THE YOUNG BABIES WHO ARE<br />

STILL TOO SMALL TO RECEIVE SOME OF<br />

THE VACCINES OR THE ELDERLY WHO<br />

CAN’T GET BOOSTERS ETC.<br />

Imagine a new born getting measles? If enough<br />

people are not vaccinated then the virus finds more<br />

ways to travel and infect the weak. If the virus mutates<br />

then even the vaccinated are more at risk. When<br />

there is another outbreak people like Izzy and other<br />

immune compromised people can’t receive boosters.<br />

They can’t protect themselves from the outbreaks.<br />

WITH SOCIAL MEDIA THE ANTI-VAXXER<br />

MOVEMENT HAS CAUSED MORE<br />

AND MORE OUTBREAKS. PEOPLE<br />

ARE BELIEVING MORE AND MORE<br />

“FACEBOOK MEDICAL PAGES” OR<br />

“FALSE LINKS AND STORIES”.<br />

I often urge people to do relevant research<br />

on more reputable sites. Think of journalistic<br />

sensationalism - everyone loves a dramatic story.<br />

You get people that love creating this drama and<br />

seeing how far their links go.<br />

PEOPLE BELIEVE THINGS THEY READ<br />

ESPECIALLY IF IT CONTAINS WORDS<br />

LIKE “SCIENTIFIC” OR “MEDICAL”, BUT<br />

THEY NEVER CHECK THE AUTHENTICITY<br />

OF THE DATA OR LINKS. I’VE HEARD<br />

AMAZING THINGS LIKE “POISONS IN<br />

VACCINES” AND “PHARMACEUTICAL<br />

GAIN”. THINK ABOUT IT; IF THE POISONS<br />

LINK HAD ANY TRUTH IN IT DO YOU<br />

THINK DOCTORS AND SCIENTISTS<br />

WOULD VACCINATE THEIR CHILDREN?<br />

The autism link that was published all those years<br />

ago has been proven to be false and the paper was<br />

removed from the medical journals after the doctor<br />

admitted to lying and he was stripped of his medical<br />

license. But the damage was done and parents<br />

believed it to be true and stopped vaccinating.<br />

Some natural doctors jumped on the bandwagon<br />

and many started selling their natural vaccines, books<br />

and remedies.<br />

People like my Izzy can’t fight these diseases and rely<br />

on the healthy population to be vaccinated. When<br />

there are outbreaks, I sit with so much fear and anger,<br />

praying my little girl will be safe.<br />

SHE NEEDS OTHER CHILDREN AND<br />

ADULTS TO BE VACCINATED TO KEEP<br />

HER, AND OTHERS LIKE HER, SAFE.<br />

Mrs. Kyara Bergstrom: Head of Research and Complementary <strong>Health</strong> at the Netcare Breast Care Centre of Excellence as well as<br />

C.O.O of The Pink Parasol Project (www.pinkparasol.co.za) Correspondence: Kyara.Bergstrom@netcare.co.za<br />

41 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

CHILDHOOD<br />

OBESITY<br />

AND WHY IT MATTERS WHAT<br />

CHILDREN EAT AT SCHOOL<br />

Francette Bekker<br />

School-aged children spend a large part of their day in the school<br />

environment and consume about a third of their daily energy<br />

requirements while at school.<br />

n an effort to manage and prevent childhood<br />

obesity, schools have become the focus of many<br />

nutrition interventions. Worldwide the obesity<br />

trends are increasing, and in <strong>South</strong> Africa one<br />

in almost every four school-aged children is either<br />

overweight or obese. The prediction is that these<br />

numbers will continue to rise at alarming rates. The<br />

risk is that an overweight or obese child will more<br />

often than not grow up to be an overweight or<br />

obese adult.<br />

OBESITY, AS WE KNOW, GOES HAND-<br />

IN-HAND WITH MANY LIFESTYLE<br />

ILLNESSES INCLUDING DIABETES,<br />

HEART DISEASE, AND CANCER. THE KEY<br />

IS TO TARGET CHILDREN WHILE THEY<br />

ARE STILL YOUNG AND DEVELOPING<br />

THEIR EATING HABITS.<br />

Registered dietitian, Francette Bekker was the<br />

principal researcher in a <strong>South</strong> <strong>African</strong> study about<br />

school tuck shops that was published in the Public<br />

<strong>Health</strong> Nutrition journal in May <strong>2017</strong>. The study<br />

compared the eating habits of children in a school<br />

with a healthy tuck shop to the eating habits of<br />

children in a school with a regular tuck shop. The<br />

healthy tuck shop offered a variety of items with<br />

no added sugar, low in salt, low in saturated fat<br />

and where possible high in fibre including slushies<br />

(fruit juice with crushed ice), iced lollies (frozen<br />

diluted fruit juice), small chicken sandwiches, sliced<br />

fruit, nuts, popcorn (air-popped) and oven-baked<br />

samoosas, while the regular tuck shop offered<br />

sweets, hamburgers, pies, pizza, potato crisps and<br />

carbonated cold drinks. The study had a number<br />

of interesting findings.<br />

Children in a school with a healthy tuck shop<br />

brought significantly more healthy items to school in<br />

their lunchboxes (such as fruit and water) compared<br />

to children in a school with a regular tuck shop.<br />

In the school with the healthy tuck shop children<br />

also had a more positive attitude towards fruits<br />

and vegetables. The younger children were more<br />

favorable towards the concept of having a healthy<br />

tuck shop at school, but despite that, children from<br />

all age groups supported and bought items at the<br />

healthy tuck shop.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong> * 42


FOCUS ON<br />

LUNCHBOXES<br />

When asked to make suggestions children had<br />

many ideas about what else they would like to have<br />

available at their healthy tuck shop - including <strong>South</strong><br />

<strong>African</strong> favorites like biltong and braaivleis.<br />

Overall the results suggested that children’s eating<br />

behaviours at school can be positively influenced<br />

when they are exposed to healthy food and<br />

beverages from a young age. But unfortunately, the<br />

researchers had another unexpected yet fascinating<br />

finding. Children in the school with a healthy tuck shop<br />

did not only bring more healthy items to school in their<br />

lunchboxes but compared to children in a school with<br />

a regular tuck shop, their lunchboxes also contained<br />

significantly more unhealthy items (like sweets and<br />

potato crisps).<br />

This was possible because they could not buy these<br />

items while at school. So, in this case, the many positive<br />

influences of the healthy tuck shop was counteracted<br />

by additional unhealthy items in lunchboxes<br />

brought from home.<br />

HAVING A SCHOOL FOOD POLICY IN<br />

PLACE THAT ENCOURAGES CHILDREN<br />

TO BRING HEALTHY FOOD TO SCHOOL IS<br />

AN OPTION, BUT THAT IS NOT THE ONLY<br />

ANSWER. PARENTS WHO ARE PACKING<br />

LUNCHBOXES, BUYING GROCERIES<br />

AND PREPARING MEALS AT HOME ARE<br />

CHILDREN’S ROLE MODELS, & THEY NEED<br />

TO BECOME MORE INVOLVED IN THE<br />

FIGHT AGAINST CHILDHOOD OBESITY.<br />

Parents must realise the importance of providing<br />

healthy food and beverages and know the risks<br />

involved of having an overweight or obese child.<br />

ALTHOUGH CHILDREN LIKE TO<br />

HAVE A CHOICE IN WHAT THEY EAT,<br />

MANY CHILDREN IN BEKKER’S STUDY<br />

PREFERRED A BALANCE AND TREATS<br />

PER OCCASION ONLY, BECAUSE THEY<br />

WERE SCARED OF BECOMING FAT. BY<br />

LIMITING THE VARIETY ON DISPLAY IN<br />

TUCK SHOPS AND MARKETING HEALTHY<br />

FOOD FOR SALE, CHILDREN MAY BE<br />

ENCOURAGED TO MAKE HEALTHIER<br />

FOOD CHOICES.<br />

The same applies at<br />

home – when there is a<br />

wide variety available,<br />

children tend to make<br />

unhealthy choices.<br />

Involve children and<br />

teach them about<br />

food, listen to their<br />

suggestions and then<br />

also guide them to<br />

make better food and<br />

beverage choices at<br />

school and home.<br />

Having healthy tuck shops at schools may not be<br />

the full solution to the obesity epidemic, but it is an<br />

excellent place to start.<br />

PARENTS AND SCHOOLS WHO ARE SEEKING ADVICE CAN USE<br />

THE ASSOCIATION FOR DIETETICS IN SOUTH AFRICA (ADSA)<br />

WEBSITE TO SEARCH FOR A REGISTERED DIETITIAN IN THEIR<br />

AREA. THERE ARE ALSO ORGANISATIONS THAT GIVE GUIDANCE<br />

AND HAVE ONLINE TOOLS FOR SETTING UP HEALTHY TUCK<br />

SHOPS AT SCHOOLS. THESE INCLUDE THE DISCOVERY VITALITY<br />

SCHOOLS PROGRAMME HEALTHY TUCK SHOP GUIDELINES &<br />

THE WOOLWORTHS HEALTHY TUCK SHOP GUIDE.<br />

Francette Bekker: Registered Dietitian (SA). Correspondence: Please contact the relevant sub-editor as well as cc the<br />

Editor-in-Chief for more information.<br />

43 *<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

PROGNOSTIC &<br />

ONCOLOGY<br />

PREDICTIVE<br />

MARKERS IN<br />

BREAST CANCER<br />

Georgia Demetriou<br />

Biomarkers can be determined in numerous<br />

ways, some are identified in easily obtained<br />

body fluids such as plasma, serum, and urine,<br />

but many biomarkers can only be identified<br />

on tumour tissue from immunohistochemical stains,<br />

DNA and RNA. In many cases biomarkers are<br />

initially identified without being placed in either the<br />

prognostic or predictive biomarker category, over<br />

time the prognostic value of the biomarker may<br />

become apparent and in many cases, therapeutic<br />

options are subsequently developed to target the<br />

prognostic marker making it a predictive marker too.<br />

A predictive marker may be able to define the<br />

benefit of a therapeutic intervention or its potential<br />

futility, allowing for far more personalized and patientspecific<br />

interventions. Some serum biomarkers can be<br />

used to monitor treatment response. The utility of a<br />

particular biomarker may be particular to a single<br />

tumour site or be of value in more than one cancer.<br />

OESTROGEN(ER) AND PROGESTERONE<br />

(PR) RECEPTOR EXPRESSION IS AN<br />

INDEPENDENT PROGNOSTIC FACTOR<br />

IN BREAST CANCER. PATIENTS WITH ER<br />

AND/OR PR POSITIVE TUMOURS HAVE<br />

A BETTER SURVIVAL THAN HORMONE<br />

RECEPTOR NEGATIVE TUMOURS. THE FIVE<br />

YEAR SURVIVAL (ALL STAGES) OF BREAST<br />

CANCER IS IN THE REGION OF 83% IN THE<br />

ER+/PR+ GROUP VERSUS 69% IN PATIENTS<br />

WITH “DOUBLE NEGATIVE” DISEASE.<br />

A high cellular expression of<br />

ER and PR predicts for benefit<br />

from endocrine blockade in<br />

the adjuvant and metastatic<br />

setting. Tumour hormone<br />

receptors can change during<br />

the course of disease with the<br />

ER status of metastatic disease<br />

differing from the primary in<br />

Georgia Demetriou 20% of cases. The PR expression<br />

can be lost in up to 40% of metastatic lesions when<br />

compared to the primary lesion. This information<br />

has resulted in a change in practice where the<br />

reassessment of a metastatic lesions hormone<br />

receptors by repeated biopsy is advised on the<br />

diagnosis of a metastasis if the lesion is amenable to<br />

sampling without creating undue risk from procedural<br />

complications, in some cases, it may influence<br />

treatment planning.<br />

Her2 gene amplification leads to overexpression of<br />

its receptor on the cell membrane. Over expression<br />

of Her2 results in increased proliferation, angiogenesis<br />

and inhibition of apoptosis. Overall Her2 positive<br />

tumours are more aggressive and have a worse<br />

prognosis compared to those that are negative.<br />

ASSESSMENT OF HER2 STATUS IS<br />

ESSENTIAL IN ALL BREAST CANCER<br />

PATIENTS TO DETERMINE PATIENT<br />

ELIGIBILITY FOR HER2-TARGETED<br />

THERAPY.<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 44


FOCUS ON<br />

HER2<br />

HER2 STATUS PREDICTS OUTCOMES<br />

IN BREAST CANCER, INCLUDING<br />

A RESPONSE TO TRASTUZUMAB,<br />

PERTUZUMAB, AND TDM-1, IT ALSO<br />

PREDICTS THE RESPONSE TO VARIOUS<br />

TYROSINE KINASE INHIBITORS, TAXANE<br />

AND ANTHRACYCLINE CHEMOTHERAPY<br />

AND A RELATIVE RESISTANCE TO<br />

TAMOXIFEN.<br />

Four phase III clinical trials enrolled more than 13 000<br />

pts, these studies (HERA, Combined B31 & N9831<br />

analysis and the BCIRG006) established the benefit<br />

of a year’s trastuzumab in the adjuvant treatment<br />

of Her2 positive breast cancer. To date studies of a<br />

shorter trastuzumab duration have been unable to<br />

demonstrate noninferiority when compared to a<br />

year’s treatment.<br />

Lapatinib is a small molecule tyrosine kinase inhibitor<br />

that, like trastuzumab, blocks the activity of the Her2<br />

protein, but it does so by a different mechanism.<br />

Lapatinib binds to the intracellular part of the Her2<br />

protein and is a potent, reversible inhibitor of ErbB1<br />

and ErbB2, which are members of a receptor tyrosine<br />

kinase family.<br />

Like ER and PR expression Her2 expression can change<br />

over time and can vary between lesions requiring<br />

repeat biopsy when metastasis occurs if feasible or<br />

if there is a progression of the disease. Both primary<br />

and secondary resistance to trastuzumab can occur<br />

with the expansion of tyrosine kinase inhibitors in the<br />

second line metastatic setting and beyond.<br />

Ki 67 a nonhistone protein which is universally<br />

expressed among proliferating cells is expressed in G1,<br />

S and G2 phases of the cell cycle with a peak during<br />

mitosis. Ki 67 usually has a low proliferative activity in<br />

ER-positive tumours, with high levels of ki 67 at baseline<br />

indicating an aggressive tumour.<br />

A high pre-treatment score is associated with<br />

a good chance of achieving a complete<br />

pathological response to chemotherapy and<br />

thus paradoxically a good long-term outcome.<br />

Post neoadjuvant chemotherapy measurement<br />

of ki 67 is a strong predictor of recurrence-free and<br />

overall survival.<br />

Cyclin D1 is localized on chromosome 11q23 and<br />

has been identified in 20% of breast cancers, it<br />

has a strong correlation with ER and PR expression<br />

levels and has predictive value in hormone<br />

receptor positive patients as its co-amplification<br />

and overexpression is a predictor of inadequate<br />

response to anti-estrogen treatments.<br />

THE ONCOLOGICAL AGE OF<br />

PERSONALIZED AND MOLECULAR<br />

MEDICINE HAS MOVED FROM<br />

THE LAB TO OUR CLINICS AND IS<br />

RELEVANT IN EVERYDAY PRACTICE.<br />

STRONG PROGNOSTIC AND<br />

PREDICTIVE MARKERS HAVE<br />

IMPROVED PATIENT OUTCOMES AND<br />

WILL HOPEFULLY CONTINUE TO IN<br />

THE FUTURE.<br />

DEFINITIONS:<br />

BIOMARKER<br />

A CHARACTERISTIC THAT CAN BE OBJECTIVELY<br />

MEASURED AND EVALUATED IN A PATHOLOGIC<br />

PROCESS OR A TUMOUR<br />

PROGNOSTIC MARKER<br />

A BIOMARKER THAT PROVIDES INFORMATION ABOUT<br />

A PATIENT’S OVERALL OUTCOME REGARDLESS OF THE<br />

TREATMENT A PATIENT RECEIVES<br />

PREDICTIVE MARKER<br />

A BIOMARKER THAT PROVIDES INFORMATION ABOUT<br />

THE THERAPEUTIC EFFECT OF AN INTERVENTION<br />

Georgia Demetriou: Senior Consultant in the Division of Medical Oncology at the University of Witwatersrand Faculty of <strong>Health</strong><br />

Sciences and Charlotte Maxeke Johannesburg Academic Hospital since 2004. She is Head of a General Medicine Undergraduate<br />

Academic teaching unit for the Department of Internal Medicine at Charlotte Maxeke Johannesburg Academic Hospital.<br />

Correspondence: georgiademetriou@hotmail.com<br />

45 *<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>


FOCUS ON<br />

SOUTH AFRICA’S<br />

CULTURAL OBSESSION WITH FOOD &<br />

THE PSCYHOLOGY OF WEIGHT LOSS<br />

HOW GASTRIC BYPASS PATIENTS<br />

‘LEARN TO EAT AGAIN’<br />

Martina Nicholson<br />

Obesity is a growing concern in <strong>South</strong> Africa, particularly because<br />

of the lifestyle diseases associated with it, including type 2 diabetes,<br />

hypertension and heart disease.<br />

SURGERY, OBESITY & METABOLISM<br />

Gastric bypass surgery is an increasingly<br />

popular treatment option for appropriate<br />

patients, however surgery alone cannot<br />

address the unhealthy relationship with<br />

food that frequently leads to obesity.<br />

“OFTEN PEOPLE REWARD OR COMFORT<br />

THEMSELVES WITH FOOD, WHICH IS<br />

EATING FOR PSYCHOLOGICAL RATHER<br />

THAN NUTRITIONAL REASONS, AND,<br />

OVER TIME, THIS CAN BECOME DEEPLY<br />

INGRAINED AND MAY LEAD TO OBESITY,”<br />

EXPLAINS CHARLENE MCINTOSH,<br />

ONE OF THE PSYCHOLOGISTS IN THE<br />

MULTIDISCIPLINARY TEAM SUPPORTING<br />

GASTRIC BYPASS PATIENTS OF GENERAL<br />

SURGEON, DR GERT DU TOIT, AND HIS<br />

SURGICAL PARTNER DR IVOR FUNNELL,<br />

WHO HEAD UP THE BARIATRIC SURGERY<br />

CENTRE AT NETCARE ST AUGUSTINE’S<br />

HOSPITAL.”<br />

“Another aspect that appears to be driving obesity<br />

is the central role of food in <strong>South</strong> <strong>African</strong> culture, by<br />

which I mean that many of our social interactions<br />

tend to revolve around eating,” she explains.<br />

“We often meet friends and family for a meal, tea<br />

and cake, shisinyama or a braai. For people who are<br />

grappling with their weight, this can make it even<br />

harder for them to exercise self-control, particularly if<br />

they feel social pressure to eat,” says McIntosh.<br />

Dr Du Toit, who specialises in complex digestive<br />

laparoscopic procedures, says that gastric bypass<br />

surgery is not to be undertaken lightly and is not<br />

appropriate for all patients with obesity and related<br />

conditions.<br />

“We are committed to helping patients achieve<br />

positive health outcomes, and there is a growing<br />

body of evidence to suggest that conditions such<br />

as type 2 diabetes and hypertension can be well<br />

controlled, if not fully alleviated, with gastric bypass<br />

surgery and behavioural change,” Dr Du Toit notes.<br />

In line with the protocols of the <strong>South</strong> <strong>African</strong> Society<br />

for Surgery, Obesity and Metabolism (SASSO),<br />

prospective patients must be assessed for suitability<br />

and supported through the surgery and afterwards by<br />

a multidisciplinary team of healthcare professionals.<br />

“Patients must be dedicated and committed to<br />

making a lifelong change, otherwise the surgical<br />

intervention will be far less likely to help the individual<br />

achieve better health over the long term. For<br />

this reason, it is sometimes advisable for patients<br />

to prepare for a few additional months to make<br />

absolutely certain that they are ready for the<br />

significant lifestyle changes to ensure that they get<br />

the best out of the treatment,” explains Dr Du Toit.<br />

Dr Du Toit likens the preparation for gastric bypass<br />

surgery to that of climbing a mountain. “If you consider<br />

people who climb Mount Everest, it is the ones who<br />

never look back who are most likely to make it to the<br />

summit. Our team needs to ensure that the surgical<br />

SOUTH AFRICAN PSYCHIATRY ISSUE 2 <strong>2017</strong> * 46


FOCUS ON<br />

candidates have a similar mindset and commitment<br />

before the gastric bypass is performed.”<br />

A vital aspect of preparation for the surgery is dealing<br />

with the emotional aspects, as McIntosh explains: “The<br />

role of the psychologist is to identify and address<br />

underlying emotional trauma that may be at the<br />

root of some people’s compulsion to eat. This is a vital<br />

aspect of the holistic treatment for patients undergoing<br />

gastric bypass surgery, because the operation can<br />

change the body but the person’s mindset also needs<br />

to change to achieve lasting outcomes.”<br />

“WE EMPHASISE THAT THERE IS A<br />

DISTINCTION BETWEEN EATING<br />

BECAUSE YOU ARE HUNGRY AND<br />

EATING FOR PSYCHOLOGICAL OR<br />

SOCIAL REASONS. PEOPLE NEED TO<br />

REDEFINE THEIR RELATIONSHIP WITH<br />

FOOD, AND IN THE CASE OF OBESE<br />

PATIENTS WE ESSENTIALLY HAVE TO<br />

TEACH THEM TO EAT AGAIN.”<br />

Addressing the social pressures around eating often<br />

requires the individual’s support base, including family<br />

and friends, to develop greater awareness. “Instead of<br />

organising time together around food, as in ‘let’s meet<br />

for lunch’, it is a good idea to sensitise the person’s social<br />

circle to rather meet for a walk or other activities that do<br />

not centre around eating,” she advises.<br />

This is one of the messages conveyed in the monthly<br />

meeting of the support group for people who have<br />

either had or are considering gastric bypass surgery,<br />

hosted by dietitian Mandy Read, who is also part of<br />

the multidisciplinary team at the bariatric surgery<br />

centre. The meetings are also open to the family and<br />

friends supporting patients through their journey.<br />

“A key aspect of changing people’s emotional<br />

reliance on food is replacing comfort eating or reward<br />

eating with another pleasurable activity, such as<br />

going for a massage, having a relaxing bubble bath<br />

or learning to play a musical instrument. Interestingly,<br />

we have found that people who replace emotional<br />

eating with a creative outlet, such as painting,<br />

photography, music or gardening, tend to have better<br />

outcomes in general,” McIntosh observes.<br />

“Perhaps the most important factor is for the person to<br />

realise that they can shape their future and have real<br />

belief that their lives can be different. If a person has<br />

been morbidly obese for many years, sadly they often<br />

become used to sitting at home and feeling isolated,<br />

and cannot imagine a life beyond that.”<br />

“Imagine clothes shopping, and being so limited in<br />

your choice because you are trying to find something<br />

that is large enough to fit you, rather than shopping for<br />

clothing that makes you look and feel good. We try to<br />

help people realise that there is a life beyond obesity<br />

and help them to get to the stage where they can<br />

get full enjoyment out of life without an overreliance<br />

on food,” she adds.<br />

According to McIntosh people who have lost a<br />

lot of weight may have some difficulty reconciling<br />

the changes in their bodies with the way they see<br />

themselves. “Some patients have managed to get<br />

down to a healthy weight but will still turn sideways<br />

to go through doors as they had to when they were<br />

morbidly obese. Often there is a process of re-building<br />

a person’s self-esteem so that they can make the best<br />

of the physical transformation they have achieved,”<br />

she concludes.<br />

CENTRES OF EXCELLENCE FOR METABOLIC<br />

MEDICINE AND SURGERY<br />

There are currently five centres of excellence for<br />

metabolic medicine and surgery at Netcare hospitals,<br />

offering patients access to specialised bariatric<br />

surgery, including gastric bypass procedures.<br />

These centres of excellence are located at Netcare<br />

Sunward Park Hospital in Boksburg, Netcare St<br />

Augustine’s Hospital in Durban, Netcare Greenacres<br />

Hospital in Port Elizabeth, Netcare N1 City Hospital in<br />

Cape Town, and Netcare Waterfall City Hospital in<br />

Midrand, Gauteng. The centre at Netcare Waterfall<br />

City Hospital is the only internationally accredited<br />

centre for the treatment of bariatric and metabolic<br />

conditions in <strong>South</strong> Africa, and is the principal centre<br />

for the four other locally accredited centres of<br />

excellence located at Netcare hospitals.<br />

The dedicated multi-disciplinary teams at these<br />

centres are comprised of surgeons, endocrinologists,<br />

psychiatrists, psychologists and dietitians, among<br />

others, in line with the protocols advocated by<br />

the <strong>South</strong> <strong>African</strong> Society for Surgery, Obesity and<br />

Metabolism (SASSO), which is chaired by endocrinologist,<br />

Professor Tess van der Merwe. As director of the Centres<br />

of Excellence for Metabolic Medicine and Surgery of<br />

<strong>South</strong> Africa (CEMMS)(SA), Prof van der Merwe oversees<br />

the work of the centres of excellence, including those<br />

based at Netcare hospitals.<br />

The centres adhere to international practices to<br />

create a safe environment and to support obese<br />

patients with empathy and care. To comply with<br />

international standards, a database with statistics on<br />

each patient is maintained. Strict rules and regulations<br />

with regard to patients’ dietary environment, as<br />

well as care in ICU and wards are followed. Training<br />

facilities with specialised technology and equipment<br />

are also incorporated in the centres.<br />

Martina Nicholson Associates (MNA): on behalf of Netcare St Augustine’s Hospital Correspondence: martina@mnapr.co.za,<br />

graeme@mnapr.co.za<br />

47 *<br />

SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong>


40 SOUTH AFRICAN PSYCHIATRY ISSUE 4 2015<br />

INSTRUCTIONS TO AUTHORS<br />

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The aim of the publication is to promote best practice for optimal care.<br />

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contributors are welcome to submit content that they think might be relevant but does not broadly conform to<br />

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All content should be forwarded to the Editor-in-chief, Carol Benn - drbenncarol@gmail.com<br />

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