South African Women's Health - November 2017
South African Women's Health - November 2017
South African Women's Health - November 2017
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ISSN 2522-3941<br />
ABOUT best practice, FOR FOR optimal care<br />
careissue 1• 2 • aug/sept nov/dec <strong>2017</strong><br />
www.southafricanwomenshealth.co.za
Focus on<br />
SURGICAL BIOPSY<br />
VS CORE BIOPSY<br />
8<br />
WHEN LESS IS MORE<br />
17<br />
IT’S IN THE DNA<br />
35<br />
THE ROLE OF FAT GRAFTING<br />
IN AESTHETIC SURGERY<br />
PROGNOSTIC & PREDICTIVE<br />
38<br />
VACCINES: THE LOW DOWN<br />
44<br />
MARKERS IN BREAST CANCER<br />
SOUTH AFRICA’S OBSESSION<br />
WITH FOOD<br />
46<br />
HOW GASTRIC BYSPASS<br />
PATIENTS LEARN TO EAT AGAIN<br />
NOTE: “instructions to authors” are available at www.southafricanwomenshealth.co.za<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 3
CONTENTS<br />
NOVEMBER <strong>2017</strong><br />
5 FROM THE EDITOR<br />
6 FOCUS ON: SUB-EDITOR BIOGRAPHIES<br />
BREAST<br />
8 FOCUS ON: SURGICAL BIOPSY VS CORE BIOPSY:<br />
WHEN LESS IS MORE<br />
10 FOCUS ON: NEW TRENDS IN BREAST CANCER: MANAGEMENT<br />
& RECONSTRUCTION SURGICAL PERSPECTIVE<br />
15 GROOTE SCHUUR HOSPITAL BREAST CLINIC<br />
WOMEN IN HEALTHCARE<br />
17 FOCUS ON: IT’S IN THE DNA<br />
19 A WOMAN’S TALE<br />
23 SOUTH AFRICAN TAX AND DNA<br />
25 BE BOLD FOR CHANGE <strong>2017</strong><br />
27 STOPPING THE BLUR<br />
OBSTETRICS & GYNAECOLOGY<br />
29 HOW SOPHROLOGY HELPS PREGNANCY:<br />
A WOMAN’S JOURNEY BEFORE, DURING & AFTER<br />
AESTHETICS & RECONSTRUCTION<br />
35 FOCUS ON: THE ROLE OF FAT GRAFTING<br />
IN AESTHETIC SURGERY<br />
HEALTH & LIFESTYLE<br />
38 VACCINES: THE LOW DOWN<br />
40 IZZY’S STORY<br />
42 FOCUS ON: CHILDHOOD OBESITY AND WHY IT MATTERS<br />
WHAT CHILDEN EAT AT SCHOOL<br />
ONCOLOGY<br />
44 PROGNOSTIC & PREDICTIVE MARKERS IN BREAST CANCER<br />
SURGERY, OBESITY & METABOLISM<br />
46 SOUTH AFRICA’S CULTURAL OBSESSION WITH FOOD &<br />
THE PSYCHOLOGY OF WEIGHT LOSS HOW GASTRIC BYPASS<br />
PATIENTS ‘LEARN TO EAT AGAIN’<br />
* PLEASE NOTE: Each item is available as full text electronically and as an individual pdf online.<br />
Disclaimer: No responsibility will be accepted for any statement made or opinion expressed in the publication.<br />
Consequently, nobody connected with the publication including directors, employees or editorial team will be held liable for any<br />
opinion, loss or damage sustained by a reader as a result of an action or reliance upon any statement or opinion expressed.<br />
© <strong>South</strong> <strong>African</strong> Women’s <strong>Health</strong> This magazine is copyright under the Berne Convention. In terms of the <strong>South</strong> <strong>African</strong><br />
Copyright Act No. 98 of 1978, no part of this magazine may be reproduced or transmitted in any form or by any means,<br />
electronic or mechanical, including photocopying, recording or by any information storage and retrieval system,<br />
without the permission of the publisher and, if applicable, the author.<br />
COVER PHOTOGRAPH: Shutterstock Image<br />
Design and layout: The Source PR * Printers: Imagine It Print It<br />
4 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FROM THE EDITOR<br />
Dear Reader,<br />
Welcome to this second edition.<br />
I have thoroughly enjoyed the selection of articles sent via the<br />
various sub-editors. From one extreme of “fat positives “ of fat grafting…<br />
to obesity. Kudos to another excellent government clinic (lets hear more<br />
from others in the next edition). Loving the traction of…Woman in medicine<br />
…and thrilled to see a mentor (to myself and many) featured …Prof Kramer.<br />
Thank you to the behind the scenes team.<br />
I encourage all reading this journal to send their articles and comments.<br />
We want to hear and read about your work...as there is no doubt to the excellent quality of medical<br />
work and insights in our wonderful country.<br />
Carol Benn<br />
Editor-in-Chief<br />
Editor-in-Chief: Carol Benn - Head, Breast Unit, Helen Joseph Hospital, Netcare Breast Centre<br />
Associate Editor: Christopher P. Szabo - Head, Department of Psychiatry, University of Witwatersrand<br />
Advisory Board: Karen Appelbaum - Psychologist, Netcare Milpark Hospital<br />
Georgia Demetriou - Department of Oncology, Charlotte Maxeke Johannesburg Academic Hospital<br />
Franco Guidozzi - Faculty of <strong>Health</strong> Sciences, University of Witwatersrand<br />
Inge Kriel - Oncology Care Physician, Milpark Breast Care Centre of Excellence<br />
Anna Sparaco - HPB practice, Wits Donald Gordon Medical Centre<br />
Tess Van Der Merwe - Honorary Professor and Researcher in the Department of Endocrinology, University of Pretoria<br />
Marisse Venter - Plastic and Reconstructive Surgeon, Netcare Milpark Hospital<br />
Acknowledgement: Thanks to Lisa Selwood for assistance with proof reading<br />
Advertising: The Source Public Relations<br />
Design and Layout: Michelle Haskins Printer: Imagine it Print It<br />
Web: www southafricanwomenshealth.co.za<br />
Contact Person: Vanessa Beyers - vanessa@thesourcepr.co.za<br />
<strong>South</strong> <strong>African</strong> Women’s <strong>Health</strong> is published quarterly by The Source Public Relations Group.<br />
Its mission is to communicate the latest news and developments in the area of <strong>South</strong> <strong>African</strong> Women’s <strong>Health</strong>.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 5
SECTION EDITORS<br />
Focus On SECTION EDITORS<br />
EDITOR & SECTION EDITOR: BREAST<br />
PROF CAROL BENN<br />
Prof Carol-Ann Benn is a Fellow of the<br />
College of Surgeons of <strong>South</strong> Africa with<br />
a special interest in Breast Disease. Her<br />
capacity as Head of the Breast Unit of<br />
Helen Joseph Hospital proves her long<br />
commitment to clinical excellence in<br />
this field of medical speciality.<br />
Prof Benn offers service to society and the greater medical<br />
community, (both local and international), through her<br />
contributions, published and presented, and she is recognised<br />
internationally as a leader in Breast Disease. As lecturer in the<br />
Department of Surgery at the University of Witwatersrand, she<br />
contributes towards the education of healthcare professionals.<br />
Through the organisation of foreign and private funding, Prof<br />
Benn was able to establish the Breast <strong>Health</strong> Foundation,<br />
various Breast <strong>Health</strong> Care forums and outreach programmes<br />
and is a representation on numerous Medical Boards and<br />
<strong>Health</strong> Care Committees. Prof Benn has paved the way for the<br />
improvement of women’s health care, has contributed towards<br />
the uplifting of women in society and has opened channels for<br />
public awareness of breast health.<br />
She established the Netcare Breast Care Centre of Excellence at<br />
Milpark Hospital, Johannesburg, which co-ordinates national<br />
efforts for the specialised management of breast conditions<br />
to all women. In addition to her positions of responsibility,<br />
Prof Benn manages continuing research and research outputs.<br />
Numerous awards testify to her esteemed position in the<br />
medical field and in <strong>South</strong> <strong>African</strong> society.<br />
SECTION EDITOR: ONCOLOGY<br />
DR GEORGIA DEMETRIOU<br />
Dr Georgia Demetriou has been a<br />
Senior Consultant in the Division of<br />
Medical Oncology at the University<br />
of Witwatersrand Faculty of <strong>Health</strong><br />
Sciences and Charlotte Maxeke<br />
Johannesburg Academic Hospital since<br />
2004 and served as Acting Head of the Division from September<br />
2013 to June 2014. She is Head of a General Medicine<br />
Undergraduate Academic teaching unit for the Department of<br />
Internal Medicine at Charlotte Maxeke Johannesburg Academic<br />
Hospital.<br />
She has been local Principal Investigator and National Principal<br />
Investigator on 15 multinational clinical trials particularly in<br />
the field Breast Cancer. Dr Demetriou serves on the Executive<br />
Committee of the <strong>South</strong> <strong>African</strong> Society of Medical Oncology as<br />
Treasurer of the society, the <strong>South</strong> <strong>African</strong> Oncology Consortium<br />
Board of Directors as Chairperson of the board and on the<br />
Executive Committee of the Breast Interest Group of <strong>South</strong> Africa<br />
as the Chairperson of the committee.<br />
She is an examiner, trainer and moderator for the Certificate<br />
Medical Oncology for College of Medicine of <strong>South</strong> Africa<br />
sub specialist qualifying degree for Medical Oncology.<br />
Dr Demetriou has co-authored papers in peer-reviewed journals,<br />
as well as presenting at local and international scientific<br />
meetings. Women’s cancers and health in particular is a major<br />
focus of work.<br />
Correspondence: georgiademetriou@hotmail.com<br />
Correspondence: drbenncarol@gmail.com<br />
SECTION EDITOR: OBSTETRICS & GYNAECOLOGY<br />
PROF FRANCO GUIDOZZI<br />
SECTION EDITOR: HEALTH & LIFESTYLE<br />
DR INGE KRIEL<br />
Dr Inge Kriel is an Oncology<br />
Care Physician affiliated with the<br />
internationally accredited Milpark<br />
Breast Care Centre of Excellence.<br />
She assists breast cancer survivors<br />
with screening for recurrence of the primary cancer and<br />
development of new cancers, management of late and longterm<br />
effects of cancer and cancer treatment, promotion of<br />
healthy lifestyle behaviours, and co-ordination of care with<br />
other oncology specialists, to ensure that patients receive the<br />
highest quality care.<br />
Correspondence: ingekriel84@gmail.com<br />
Professor Emeritus Franco Guidozzi<br />
is a Wits graduate and the erstwhile<br />
Academic Head of the Wits Department<br />
of Obstetrics and Gynaecology. He<br />
is a past President of the Society of<br />
Obstetricians and Gynaecologists,<br />
a Past President of the College of<br />
Obstetricians and Gynaecologists of<br />
the Colleges of Medicine of <strong>South</strong> Africa, a past president of<br />
the <strong>South</strong> <strong>African</strong> Menopause Society and a Past Secretary<br />
of the <strong>South</strong> <strong>African</strong> Royal College of Obstetricians and<br />
Gynaecologists.<br />
He has published over 120 articles in peer reviewed and nonpeer<br />
reviewed journals. He retired from the Wits Department<br />
of Obstetrics and Gynaecology in 2015, is still in fulltime<br />
private practice and enjoys reading, bonsai gardening and<br />
attending to his koi fish. He is married to Yolande, an advocate,<br />
has three daughters, all of whom are doctors, and loves<br />
laughing at himself.<br />
Correspondence: guidozzif@gmail.com<br />
6 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
SECTION EDITORS<br />
Focus On SECTION EDITORS<br />
SECTION EDITOR: AESTHETICS & RECONSTRUCTION<br />
DR MARISSE VENTER<br />
Dr Marisse Venter is a Plastic and<br />
Reconstructive Surgeon at Netcare<br />
Milpark Hospital. She has a special<br />
interest in breast reconstruction and<br />
cosmetic surgery. She qualified from<br />
the University of Cape Town in 2002.<br />
Her specialization encompassed 4 years of general surgery<br />
and a further 4 years of plastic surgery at the University of the<br />
Witwatersrand from where she qualified as a plastic surgeon.<br />
She is registered with the <strong>Health</strong> Professions Council of <strong>South</strong><br />
Africa as a Plastic and Reconstructive Surgeon, a member<br />
of the Association of Plastic and Reconstructive Surgeons of<br />
<strong>South</strong>ern Africa (APRSSA) and International Society of Aesthetic<br />
Plastic Surgery. Dr Venter has won numerous national and<br />
International awards for her research done on adipose<br />
tissue. Dr Venter has dedicated her life to the beautifying of<br />
women through breast reconstruction, facial, breast and body<br />
cosmetic surgery. All women deserve a body they would be<br />
comfortable with.<br />
Correspondence: dr.mventer@gmail.com<br />
SECTION EDITOR: SURGERY, OBESITY & METABOLISM<br />
(CEMMS)(SA).<br />
PROF TESS VAN DER MERWE<br />
Advisory Board member, Tess van<br />
der Merwe, is an Honorary Professor<br />
and Researcher in the Department of<br />
Endocrinology, University of Pretoria<br />
and CEO of the 11 Centres for Metabolic<br />
Medicine and Surgery of <strong>South</strong> Africa<br />
She is also the Director of the Waterfall City Hospital Metabolic<br />
Medicine and Surgery Centre Research group and is a full time<br />
clinician at this hospital.<br />
She was the Honorary Secretary of the International Association<br />
for the Study of Obesity for a period of 8 years and currently<br />
remains the Africa consultant for this association.<br />
In addition, she is the Chair of the <strong>South</strong> <strong>African</strong> Society for<br />
Surgery, Obesity and Metabolism (SASSO) and has served this<br />
organisation for more than 25 years. Professor van der Merwe<br />
established the CEMMS (SA) in 2005 and to date remains as<br />
the CEO of CEMMS(SA).<br />
SECTION EDITOR: WOMEN IN HEALTHCARE<br />
DR ANNA SPARACO<br />
Anna Sparaco is a Wits graduate,<br />
having obtained a BSc Honours in<br />
anatomical sciences under the tutelage<br />
of Prof PV Tobias. After lecturing for<br />
2 years in anatomical science,she<br />
entered her medical training at the Wits<br />
Medical School. After graduating, she spent 3 years in London<br />
at Guys and St Thomas’ culminating in gaining entrance into<br />
the Royal College of Surgeons of England. On returning to <strong>South</strong><br />
Africa, she entered into a Hepatopancreaticobiliary fellowship<br />
and concurrently was asked to join the Johannesburg transplant<br />
team and engaged in assisting in developing the liver transplant<br />
program.<br />
To this end, and having been awarded the Miller Travelling<br />
Fellowship, she spent 3 months at the University Medical Centre<br />
in Omaha, Nebraska. Subsequently, she joined Prof Rene<br />
Adam at the Hospital Paul Bruix in France where she learnt<br />
about liver resection and finally visited Professor Buchler in<br />
Heidelberg where she was exposed to aggressive pancreatic<br />
surgery. She currently has a predominantly HPB practice at<br />
the Wits Donald Gordon Medical Centre and has recently<br />
co-founded the Centre for Digestive Diseases and Liver <strong>Health</strong><br />
at the Rosebank Hospital.<br />
With the establishment of the Women’s <strong>Health</strong> Journal, she<br />
was invited to subedit a section entitled “Women in <strong>Health</strong>care”.<br />
This coincided with the creation of the Women in <strong>Health</strong>care<br />
group who’s aim is to create a virtual and social networking<br />
platform for all women in medicine. Birth was given to this<br />
group because of the realisation that the current networking<br />
structure - both formal and informal - are predominantly directed<br />
towards the male gender as they have been the predominant<br />
participants in the work space and in fact still continue to be<br />
so. WIH will endeavour to host networking functions and also to<br />
host workshops that deal with social media and your practice,<br />
flow of money through your practice, medical aid fraud and<br />
so forth. The WIH section in the journal will aim at providing<br />
similar such information and also to look at the role and profile<br />
of women in medicine.<br />
Correspondence: anna.sparaco@surgicalspecialist.co.za<br />
Correspondence: tessvdm@iafrica.com<br />
NOTE: “instructions to authors” are available at www.southafricanwomenshealth.co.za<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 7
FOCUS ON<br />
SURGICAL BIOPSY VS CORE BIOPSY<br />
Lucy Van Schalkwyk<br />
Breast complaints, specifically breast masses, should be investigated by<br />
the tried and tested process of triple assessment: the findings from three<br />
modalities – clinical examination, radiology (mammogram & ultrasound)<br />
and breast biopsy - are combined to arrive at a final diagnosis.<br />
he breast biopsy may be obtained by several<br />
different methods, which can broadly be<br />
classified as percutaneous or surgical.<br />
Percutaneous biopsies are performed<br />
by passing a hollow core biopsy needle through<br />
the skin of the breast into the suspicious lesion to<br />
extract a core of tissue (hence the synonym core<br />
biopsy), allowing for a histopathological diagnosis.<br />
Vacuum assisted biopsy, also a form of percutaneous<br />
breast biopsy, relies on a large gauge core needle<br />
attached to a vacuum-powered biopsy system to<br />
obtain several large cores of tissue. Surgical biopsy<br />
entails removal of a portion (incisional) or the whole<br />
(excisional) of a suspicious breast lesion via a skin<br />
incision, for diagnostic purposes.<br />
SURGICAL BIOPSY IS USUALLY<br />
PERFORMED UNDER GENERAL<br />
ANAESTHESIA, BUT MAY OCCASIONALLY<br />
BE PERFORMED UNDER LOCAL<br />
ANAESTHESIA.<br />
Due to its accuracy, which approaches 100%, 1<br />
surgical biopsy was historically considered the<br />
gold standard for the tissue diagnosis of breast<br />
abnormalities. Nowadays, surgical biopsy has<br />
largely been superseded by the percutaneous<br />
methods. The British Association of Breast Surgeons<br />
surgical guidelines state that in at least 90% of cases,<br />
preferably >95% of cases, breast cancer should be<br />
diagnosed by percutaneous means 2 .<br />
ACCURACY<br />
It is hardly surprising that surgical biopsy is slightly more<br />
accurate than needle biopsy – the tissue retrieved by<br />
a needle biopsy only represents a small area of the<br />
entire lesion, while surgical biopsy removes a larger<br />
portion or the entire suspicious lesion. The accuracy<br />
of needle biopsy can however be improved by<br />
imaging guidance, such as stereotactic or ultrasound<br />
guidance, which allows for visual confirmation of<br />
accurate sampling 3 .<br />
MINIMALLY INVASIVE<br />
Core needle biopsy is performed via a 3 – 4 mm<br />
stab incision in the breast, while surgical biopsy is<br />
performed though standard surgical incisions on<br />
the breast. While most surgeons attempt to place<br />
these incisions in cosmetically acceptable areas, for<br />
example peri-areolar or in the inframammary fold,<br />
poorly placed incisions are still encountered and can<br />
result in significant cosmetic disfigurement. Obtaining<br />
a diagnosis via percutaneous biopsy may spare many<br />
patients with benign pathology unnecessary scars on<br />
their breasts 4 . Core biopsies also cause less long-term<br />
distortion and scarring of the breast parenchyma 5<br />
- post-surgical fibrosis and fat necrosis can make<br />
the interpretation of subsequent mammograms<br />
challenging and may be difficult to distinguish from<br />
a malignancy.<br />
FEWER COMPLICATIONS<br />
Core biopsies are minimally invasive, and are usually<br />
performed under local anaesthesia in the outpatient<br />
setting - this significantly decreases the time to return<br />
to normal activity, compared to surgical biopsy (core<br />
biopsy: average 1.5 days, surgical biopsy average<br />
3.5 days). Core biopsies are associated with a<br />
significantly lower complication rate than surgical<br />
biopsies (surgical biopsy: 2 – 10% vs core biopsy:<br />
0.09 – 0.72%) and when complications do occur<br />
with core biopsies, they tend to be minor (e.g. minor<br />
bleeding, bruising, haematomas and mild pain) and<br />
are managed conservatively 4 .<br />
Scars from multiple poorly orientated surgical<br />
incisions on both breasts.<br />
Photograph courtesy of Professor Carol Ann Benn<br />
Scars from multiple poorly orientated surgical incisions on both breasts.<br />
Photograph courtesy of Professor Carol-Ann Benn<br />
8 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
PRE-OPERATIVE<br />
DIAGNOSIS<br />
BREAST<br />
SINGLE SURGERY<br />
Perhaps one of the greatest advantages of core<br />
needle biopsy over surgical biopsy is that patients<br />
diagnosed with breast cancer on a core biopsy are<br />
more likely to have their cancer managed in a single<br />
surgery 6-8 . The American National Accreditation<br />
Program for Breast Centres (NAPBC) states in its<br />
latest standards manual that breast units seeking<br />
accreditation should avoid surgical biopsy as an<br />
initial diagnostic approach, as it does not allow for<br />
treatment planning and is associated with a high reexcision<br />
rate 9 .<br />
IN SUMMARY:<br />
WHILE SURGICAL BIOPSY IS STILL<br />
APPROPRIATE IN SELECTED PATIENTS,<br />
PERCUTANEOUS CORE BIOPSY OFFERS<br />
MANY SIGNIFICANT ADVANTAGES AND<br />
IS NOW CONSIDERED THE STANDARD<br />
OF CARE FOR BREAST DIAGNOSIS.<br />
References:<br />
1. Bruening W, Fontanarosa J, Tipton K et al. Systematic Review: Comparative<br />
Effectiveness of Core-Needle and Open Surgical Biopsy to Diagnose Breast<br />
Lesions. Ann Intern Med. 2010;152(4):238-246.<br />
Pre-operative diagnosis affords the surgeon the<br />
opportunity to consult with appropriate specialists<br />
in the multidisciplinary cancer care team, such as<br />
radiologists, pathologists, oncologists, geneticists and<br />
plastic surgeons. It allows for planning of the surgical<br />
approach, the appropriate margin, the staging of<br />
the axilla and an appropriate reconstruction prior<br />
to placing knife to skin. Many patients are deprived<br />
of the benefit they would have derived from neoadjuvant<br />
chemotherapy by surgical biopsy 10.<br />
Despite the advantages of core needle biopsy,<br />
surgical biopsy is still indicated in certain situations,<br />
often as a supplementary procedure to a<br />
percutaneous biopsy 11 :<br />
• Lesions that are difficult to characterise on<br />
core biopsy such as atypical hyperplasia, lobular<br />
carcinoma in situ (LCIS), papillary lesions,<br />
sclerosing lesions and fibroepithelial lesions. For<br />
these lesions, a larger specimen is required to<br />
confirm the diagnosis.<br />
• A suspicious nipple discharge in the presence of<br />
a normal mammogram.<br />
• Where the suspicious lesion is in a position in the breast<br />
that is difficult to access with the biopsy needle, e.g. in<br />
close proximity to the chest wall, skin or a breast<br />
implant.<br />
• Where the findings of the triple assessment<br />
are discordant, e.g. clinical examination and<br />
mammogram are suggestive of carcinoma, but<br />
the result of the core biopsy is benign.<br />
2. Surgical Guidelines for the Management of Breast Cancer, Association<br />
of Breast Surgery at BASO 2009, Eur J Surg Onco. Retrieved from http://<br />
associationofbreastsurgery.org.uk/media/63420/surgical-guidelines-for-themanagement-of-breast-cancer-abs-baso-2009.pdf<br />
on 30/11/<strong>2017</strong><br />
3. Dillon M, Hill AK, Quinn C et al. The Accuracy of Ultrasound, Stereotactic, and<br />
Clinical Core Biopsies in the Diagnosis of Breast Cancer, With an Analysis of<br />
False-Negative Cases. Ann Surg 2005 Nov; 242(5): 701–707.<br />
4. White RR, Halperin TJ, Olson JA et al. Impact of Core-needle Breast Biopsy on<br />
the Surgical Management of Mammographic Abnormalities. Ann Surg 2001<br />
Jun;233(6):769-77.<br />
5. Dahabreh IJ, Wieland LS, Adam GP, et al. Core Needle and Open Surgical<br />
Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report [Internet].<br />
Rockville (MD): Agency for <strong>Health</strong>care Research and Quality (US); 2014 Sep.<br />
(Comparative Effectiveness Reviews, No. 139.) Results. Available from: https://<br />
www.ncbi.nlm.nih.gov/books/NBK246884/<br />
6. Kaufman CS, Delbecq R, Jacobson L. Excising the Reexcision: Stereotactic<br />
Core-needle Biopsy Decreases Need for Reexcision of Breast Cancer. World J<br />
Surg 1998 Oct;22(10):1023-7<br />
7. Yim JH, Barton P, Weber B et al. Mammographically detected breast cancer.<br />
Benefits of stereotactic core versus wire localization biopsy. Ann Surg 1996 Jun;<br />
223(6): 688–700<br />
8. James TA, Mace JL, Virnig BA et al. Preoperative Needle Biopsy Improves the<br />
Quality of Breast Cancer Surgery. J Am Coll Surg 2012 (215) 4 : 562–568<br />
9. The National Accreditation Program for Breast Centers 2018 Standards<br />
Manual. Retrieved from http://www.facs.org on 27/11/<strong>2017</strong>.<br />
10. The American Society of Breast Surgeons, Consensus Guideline on Image-<br />
Guided Percutaneous Biopsy of Palpable and Nonpalpable Breast Lesions, Nov<br />
<strong>2017</strong>. Retrieved from http://www.breastsurgeonsweb.org on 30/11/<strong>2017</strong><br />
11. The American Society of Breast Surgeons, Statement on Surgical Biopsies.<br />
Retrieved from http://www.breastsurgeonsweb.org on 27/11/<strong>2017</strong>.<br />
Lucy Van Schalkwyk: Correspondence: Please contact the relevant sub-editor, as well as cc the Editor-in-Chief<br />
for more information.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 9
FOCUS ON<br />
NEW TRENDS IN<br />
BREAST CANCER<br />
MANAGEMENT & RECONSTRUCTION<br />
SURGICAL PERSPECTIVE<br />
Carol Benn<br />
INTRODUCTION<br />
Breast cancer treatment has evolved over the<br />
last 50 years, from a disease treated mainly in the<br />
hands of the surgeon to now being a showcase for<br />
multi-disciplinary team management. Advancement<br />
in the understanding of oncological care has resulted<br />
in swings from large radical surgery (Halstedian<br />
mastectomies) to breast conserving surgery.<br />
Greater understanding of tumour biology has seen<br />
tremendous strides in the use of oncological drugs,<br />
and the paradigm shift around understanding cancer<br />
spread.<br />
SCREENING ADVANCES IN BOTH<br />
MAMMOGRAPHY, ULTRASOUND AND<br />
MRI SCANNING HAVE RESULTED IN<br />
EARLIER DETECTION OF CANCERS<br />
RESULTING IN SMALLER SURGICAL<br />
EXCISIONS IN SOME INSTANCES AS<br />
WELL AS DISCUSSION AROUND OVER<br />
OPERATING AND “UNNECESSARY<br />
MASTECTOMIES.”<br />
Advances in patient advocacy, understanding the<br />
psychological makeup of the patient and the value<br />
of breast reconstruction, particularly in immediate<br />
one-stage procedures, have necessitated a more<br />
comprehensive multi-disciplinary team approach to<br />
care.<br />
The standard surgical therapeutic option for patients<br />
with stage 1 and two breast cancers in the 21st<br />
century is breast conservation with radiation therapy.<br />
This combination has outcomes with less morbidity<br />
and at least equivalent recurrence of disease,<br />
compared to the classical radical mastectomy.<br />
Breast conservation is well supported by level 1 and<br />
2 data (National Cancer Institute, 2014) (NCCN<br />
Guidelines 2016) and is not just the thrust of women’s<br />
empowerment groups and<br />
patient preference. Survival<br />
outcomes are identical for<br />
both mastectomy and breast<br />
conserving surgery. Thus<br />
some patients may elect<br />
mastectomies.<br />
Greater public awareness<br />
regarding breast selfexamination,<br />
clinical breast<br />
Carol Benn<br />
examination, and mammographic screening<br />
have led to the detection of smaller and earlier<br />
stage breast cancers. Despite this, the incidence<br />
of advanced breast cancers has not decreased<br />
in countries with screening programmes while the<br />
incidence of advanced breast cancers remains high<br />
in LMICs without access to screening.<br />
Advanced radiological methods, including<br />
mammography, ultrasound, and MRI scanning,<br />
have detected smaller cancers allowing surgical<br />
excision with better breast conservation. Central to<br />
the acceptance of breast conservation therapy<br />
(BCT) is the importance of avoiding disfiguring<br />
cosmetic results. The conserved breast must have<br />
an acceptable aesthetic appearance. A better<br />
understanding of the psychological makeup of<br />
the cancer patient, including the importance of<br />
breast reconstruction, as an immediate one-stage<br />
procedure, has resulted in clinicians offering a wide<br />
variety of surgeries with the expectation that treating<br />
surgeons will achieve cosmetically more desirable<br />
results. Breast conserving surgery should, therefore,<br />
be considered both an oncological, as well as a<br />
cosmetic procedure, and the extent of surgical<br />
margin from the tumour will play a pivotal role in<br />
achieving this. Poor cosmetic results, due to extensive<br />
surgical resection without reconstructive techniques<br />
and radiation change, have been reported in at least<br />
20% of patients.<br />
10 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong>
PLANFOCUS<br />
A CLEAR<br />
WHO GETS WHAT SURGERY?<br />
Today there is little reason for a woman not to choose<br />
BCT.<br />
The absolute oncological indications for a<br />
mastectomy today are 2<br />
• Infla[1]mmatory breast cancer<br />
• Multicentric breast cancer<br />
Relative oncological contraindications are<br />
• Paget’s disease<br />
• Lobular Carcinomas<br />
• BRCA positive<br />
A woman may elect to have a mastectomy or a<br />
bilateral mastectomy, but this is a psychological<br />
choice, not an oncological choice (with many<br />
reasons being cited):<br />
• Strong family history<br />
• Desire to avoid radiation due to logistics<br />
or personal reasons<br />
• Sense of failure in radiology to detect a tumour<br />
either due to past experience or not wanting<br />
future mammograms<br />
• Aesthetic desires involving prosthetic reconstruction<br />
ON<br />
WHAT IS THE NEW STANDARD OF CARE IN<br />
MANAGEMENT?<br />
All patients should be discussed in the following multidisciplinary<br />
meetings;<br />
Clinical radiology meeting:<br />
In which correlation between the radiology and the<br />
core biopsy pathology is documented; including the<br />
need for further investigation.<br />
An oncology multidisciplinary meeting:<br />
The patient is discussed in the presence of all treating<br />
disciplines that play a role in the care of the patient<br />
(attending members should be from the disciplines<br />
of medical oncology; radiation oncology; radiology;<br />
pathology; surgical oncology; genetics; oncology<br />
care physicians; nurse navigation (allied care<br />
specialists: lymph oedema; physio; nutritionists).<br />
ALL DECISIONS AROUND THE ABOVE<br />
MEETINGS SHOULD BE FED BACK TO<br />
THE PATIENTS WITH A CLEAR PLAN OF<br />
ACTION AROUND TREATMENT.<br />
BEFORE ANY WOMAN DECIDES ON<br />
HER SURGERY A DETAILED DISCUSSION<br />
EXPLAINING THE FOLLOWING POINTS<br />
NEED TO BE MADE.ONCE A DIAGNOSIS<br />
OF A BREAST CANCER IS MADE; THAT<br />
CANCER DETERMINES THE OUTCOME,<br />
AND IRRESPECTIVE OF THE BRCA<br />
OR FAMILY HISTORY A BILATERAL<br />
MASTECTOMY BECOMES CHOICE NOT<br />
AN ONCOLOGICAL DECISION.<br />
The survival is equal whether a mastectomy or BCT is<br />
performed.<br />
• All woman should be counseled around the<br />
oncology rules<br />
• All woman should be discussed in a Multidisciplinary<br />
meeting<br />
• A clear plan should be presented to the patient<br />
before starting treatment<br />
• All woman should be offered the opportunity for<br />
a second opinion<br />
BREAST CANCER TREATMENT DOES<br />
NOT INVOLVE “EMERGENCY CANCER<br />
SURGERY EVER.”<br />
Breast conservation is not a contraindication in<br />
women with big tumours or woman with locally<br />
advanced breast cancer. Before discussing different<br />
surgical techniques for surgery and reconstruction lets<br />
look at oncology principles that may guide surgery<br />
choices.<br />
Each unit should have a written documentation of :<br />
• local treatment guidelines<br />
• which international guidelines are followed<br />
• which cases should be discussed that may fall<br />
outside of guidelines or require specific<br />
non-guideline based treatment choices and why<br />
DIAGNOSIS AND PATHOLOGY<br />
Radiology diagnostics includes not just mammography<br />
but also the use of breast tomosynthesis; ultrasound<br />
not just of the breast but the axilla to determine;<br />
document and perform possible needle biopsies to<br />
record lymph node involvement; Breast MRI also plays<br />
a critical role in determining extent of disease and<br />
response to oncology treatment.<br />
The gold standard of a core biopsy is critical in<br />
determining the biological profile of the breast<br />
cancer. Some units may have expertise with fine<br />
needle aspiration cytology providing the same data.<br />
Breast cancers are divided into four major subtypes:<br />
• Luminal A:<br />
• Luminal B<br />
• Her 2 enriched<br />
• Triple negative<br />
RADIATION THERAPY DISCUSSIONS<br />
All patients should have documentation of the<br />
need for radiation with breast conserving surgery.<br />
Discussions around whether the patient fits criteria<br />
for intra-operative radiation should be assessed<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 11
FOCUS ON<br />
THE PROS AND CONS<br />
according to (ASTRO <strong>2017</strong> guidelines). Need for<br />
radiation due to axillary nodal disease (1 or more<br />
involved). Whether the unit accepts and follows the<br />
Z11 protocol for radiation; thus avoiding more axillary<br />
surgery; as well as the AMAROS trial outcomes. The<br />
pros and cons of hypofractionated treatment and<br />
whether the patient fits criteria. Can radiation be<br />
avoided in certain elderly luminal A tumours.<br />
ONCOLOGY DISCUSSIONS<br />
Guidelines as to which patients do not<br />
require chemotherapy according to<br />
genetic profiling must be documented.<br />
Which patients do not require chemotherapy with<br />
node positive disease (For example: may decide<br />
extremely low Ki luminal A; low-grade lobular<br />
carcinomas )?<br />
Which early-stage breast cancer patients will start<br />
with primary chemotherapy (For example triple<br />
negatives; Her 2 enriched; High Ki luminal B)?<br />
Does your unit use specific chemotherapy regimes<br />
for different tumour subtypes? (For example TAC for<br />
triple negatives)<br />
How does your unit document response to primary<br />
chemotherapy ( clinically and radiologically)?<br />
Poor responders to primary chemotherapy are<br />
managed by:<br />
• Second line chemotherapy<br />
• Surgery<br />
Incomplete responders post chemotherapy and<br />
surgery are offered<br />
1. More oncology treatment options<br />
(CREATE for tripl negatives)<br />
2. Watch and wait<br />
What endocrine treatments are offered to what<br />
patients and for how long?<br />
1. Do you use extended adjuvant endocrine for all?<br />
2. Do you offer your young breast cancer patients an<br />
Aromatase inhibitor plus GnRH?<br />
SURGICAL PRINCIPLES<br />
Each unit should have documentation of :<br />
• What is considered an optimal surgical margin<br />
for that unit so audit of local recurrences can be<br />
monitored<br />
• Which patients are candidates for sentinel lymph<br />
node biopsies and the timing of these procedures:<br />
* At definitive surgery<br />
* Before initial surgery (in patients desiring prosthetic<br />
reconstruction wishing to avoid radiation;<br />
patients with small triple negative or Her 2<br />
enriched tumours that documentation of<br />
the extent of radiation is needed prior to<br />
starting primary chemotherapy<br />
• Patients who are candidate for intra-operative<br />
radiation therapy<br />
• Patients who can have sentinel lymph node<br />
biopsies post-primary chemotherapy once<br />
ultrasound documentation of the change of nodal<br />
status is confirmed<br />
ONCOPLASTIC PLANNING OF THE CANCER<br />
SURGERY; WITH WHAT TECHNIQUES ARE<br />
TO BE USED; WHO WILL BE PERFORMING<br />
THE SURGERY AND INTRA-OPERATIVE<br />
ASSESSMENT DOCUMENTATION OF THE<br />
SURGICAL MARGINSA PLAN OF ACTION AND<br />
PRE-SURGICAL DISCUSSION INVOLVING AT<br />
LEAST 2 SEPARATE CONSULTATIONS AROUND<br />
ONCOPLASTIC AND RECONSTRUCTIVE<br />
OPTIONS SHOULD BE DISCUSSED WITH<br />
THE PATIENT AS WELL AS WHO WILL BE<br />
PERFORMING THE SURGERY; OUTCOMES AND<br />
POTENTIAL COMPLICATIONS. ALL PATIENTS<br />
UNDERGOING PRIMARY ONCOLOGY CARE<br />
SHOULD HAVE V MARKERS PLACED PRIOR<br />
TO STARTING TREATMENT WITH CAREFUL<br />
DOCUMENTATION OF EXTENT OF DISEASE.<br />
ALLIED CARE<br />
Does your unit have radiology and oncology<br />
navigators helping patients on their cancer journey<br />
Do you offer an oncology care physician survivorship<br />
program?<br />
Are all young breast cancers offered a fertility service<br />
and discussion prior to starting treatment?<br />
What is the unit protocol on which patients are<br />
referred for genetic counseling and testing (and<br />
when)?<br />
Which patients are referred for an onco-psychology<br />
consult (and when)?<br />
Which patients are referred for lymph oedema physio<br />
(and when)?<br />
What is the unit policy on complementary oncology<br />
care and how is this managed<br />
Lets now discuss principles of oncoplastic surgery and<br />
reconstruction.<br />
THE DEFINITIONS<br />
Oncoplastic surgery is defined as techniques used at<br />
the time of breast conserving surgery. Whereas this<br />
term has been used for many years it is my opinion that<br />
it should be termed onco-reconstructive techniques.<br />
12 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong>
FOCUS ON<br />
ONCOLOGY PRINCIPLES<br />
ALLIED CARE<br />
Does your unit have radiology and oncology<br />
navigators helping patients on their cancer journey<br />
Do you offer an oncology care physician survivorship<br />
program?<br />
Are all young breast cancers offered a fertility service<br />
and discussion prior to starting treatment?<br />
What is the unit protocol on which patients are<br />
referred for genetic counseling and testing (and<br />
when)?<br />
Which patients are referred for an onco-psychology<br />
consult (and when)?<br />
Which patients are referred for lymph oedema physio<br />
(and when)?<br />
What is the unit policy on complementary oncology<br />
care and how is this managed?<br />
Lets now discuss principles of oncoplastic surgery and<br />
reconstruction.<br />
THE DEFINITIONS<br />
ONCOPLASTIC SURGERY IS DEFINED<br />
AS TECHNIQUES USED AT THE TIME OF<br />
BREAST CONSERVING SURGERY.<br />
Whereas this term has been used for many years<br />
it is my opinion that it should be termed oncoreconstructive<br />
techniques.The basis of this surgery<br />
is around understanding techniques used during<br />
breast plastic surgery; as soon as the word plastic is<br />
associated with cancer, there is often an unrealistic<br />
patient expectation.Reconstructive breast surgery is<br />
the term used for reconstruction post mastectomy be<br />
it immediate; immediate-delayed or delayed.<br />
THE FIRST RULES<br />
1. Breast reconstruction and oncoplastic surgery<br />
should be discussed with all patients prior to<br />
surgery.<br />
2. The vast majority of patients can undergo<br />
immediate reconstruction at the time of their<br />
cancer surgery (thus avoiding multiple procedures)<br />
3. Understanding the oncology principles and<br />
rules in your unit avoids unnecessary complications<br />
around reconstruction (such as which patients<br />
require radiation)<br />
THE PRINCIPLES:<br />
Tumour Factors<br />
• Understand the size of the tumour;<br />
• The position of the tumour;<br />
• The radiological and tumour information<br />
• The relationship with nipple areolar complex<br />
complex<br />
• Distance to skin<br />
Breast Factors<br />
• the size of the breast;<br />
• the consistency of the breast tissue (fatty breast<br />
can be harder to perform oncoplastic techniques<br />
on if one does not have experience the tissue pulls<br />
apart and areas of fat necrosis result from<br />
inadequate blood supply<br />
• The degree of ptosis<br />
• Previous breast surgery<br />
• Presence of prostheses (type; size and age)<br />
Patient Factors<br />
• Medical illness that may affect surgery<br />
• Habits: such as smoking<br />
• Medication that may affect surgery<br />
THE TECHNIQUES<br />
Breast conserving surgery techniques are twofold:<br />
Volume displacement:<br />
Involves moving the breast tissue around with types<br />
of parenchymal flaps. From small rotational flaps to<br />
the use of a variety of breast reduction or mastopexy<br />
techniques.<br />
Volume replacement<br />
This involves the use of importing loco-regional tissue<br />
in the vicinity of the breast cancer excision. In our<br />
unit LICAp flaps; Thoraco-epigastric flaps and regional<br />
local flaps are used commonly (with latissimus dorsi<br />
flaps used mainly for immediate or immediatedelayed<br />
medium breast reconstruction in patients<br />
post-primary chemotherapy.<br />
MASTECTOMY BASED RECONSTRUCTION<br />
Most mastectomies in our unit are skin sparing<br />
with 60% of this being nipple and skin sparing. This<br />
can be either prosthetic or autologous. Prosthetic<br />
reconstruction is mainly direct implant reconstruction<br />
in our unit without ADM (acellular dermal matrixes).<br />
The use of expander or prosthetic with ADM is reserved<br />
for a small subset of patients who have skin loss<br />
particularly in the lower poles. Prosthetic reconstruction<br />
is done once need for radiation has been accessed<br />
and is avoided in patients requiring radiation.<br />
AUTOLOGOUS RECONSTRUCTION<br />
The latissimus flap reconstruction:<br />
It is the leading workhorse in our unit in patients<br />
presenting with locally advanced breast cancer<br />
post-primary chemotherapy including in our<br />
inflammatory breast cancers. Most of these patients<br />
require immediate, delayed reconstruction involving<br />
a nipple and skin sparing mastectomy (a 48hour<br />
pathology turn-around on margins (10mm) with<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 13
margin clearance; reconstruction with the lat and<br />
OSM 48 hours later.Detailed patient counseling is<br />
suggested with a small subset of patients requiring<br />
free flaps and strict “no time delay to either radiation<br />
or chemotherapy being maintained within the unit of<br />
a minimum of 3 weeks and max allowed of 6 weeks.<br />
The Goldilocks reconstruction:<br />
Done with a modification of Nipple and skin sparing<br />
through a lateral Type 4 approach; with the addition<br />
of bilateral TE flaps is offered in some patients with<br />
breast ptosis; and over a c cup breast size.<br />
Special scenarios:<br />
The unit has a high number of locally advanced<br />
patients that are managed including those with<br />
stable or responsive metastatic disease that are<br />
offered surgery with reconstruction.<br />
A less is more approach is taken with metastatic<br />
patients requesting some form of reconstructive<br />
surgery; with the most conventional techniques being<br />
BCT with parenchymal flap reconstructions.<br />
Pregnant breast cancer patient requiring surgery<br />
also are offered local small parenchymal flap<br />
reconstruction. Elderly patients are also offered<br />
oncoplastic and breast reconstruction as long as<br />
anesthetic safety has been predetermined.<br />
IN CONCLUSION<br />
This era of breast cancer management offers for<br />
surgeons dynamic and different treatment options<br />
for patients. Today’s oncology surgeon needs to<br />
be trained in all aspects of breast cancer care<br />
from radiology to radiation. He/she needs to have<br />
comprehensive training in different plastic and<br />
reconstructive techniques to recognize which<br />
patients for which procedures and to ensure that they<br />
work with a team of competent specialists including<br />
plastic /and reconstructive surgeons so as allow best<br />
patient outcomes for their patients.<br />
References:<br />
• Extent of Primary Breast Cancer Surgery: Standards and ... - NCBI - NIH.” 22<br />
Oct. 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518938/. Accessed<br />
4 Dec. <strong>2017</strong>.<br />
• Survival is Better After Breast Conserving Therapy than Mastectomy ....” 6 Mar.<br />
2015, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595537/. Accessed 4<br />
Dec. <strong>2017</strong>.<br />
• “Clinical Practice Statements - American Society for Radiation Oncology.”<br />
https://www.astro.org/Clinical-Practice-Statements.aspx. Accessed 4 Dec. <strong>2017</strong>.<br />
• “Radiation field design in the ACOSOG Z0011 (Alliance) Trial..” 18 Aug. 2014,<br />
https://www.ncbi.nlm.nih.gov/pubmed/25135994. Accessed 4 Dec. <strong>2017</strong>.<br />
• “Regional nodal management in the light of the AMAROS trial.” https://www.<br />
ncbi.nlm.nih.gov/pmc/articles/PMC4430731/. Accessed 4 Dec. <strong>2017</strong>.<br />
Carol Benn: Head, Breast Unit, Helen Joseph Hospital. Correspondence: drbenncarol@gmail.com<br />
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FOCUS ON<br />
GROOTE SCHUUR<br />
HOSPITAL<br />
BREAST CLINIC<br />
Francois Malherbe<br />
The Groote Schuur Hospital breast clinic was founded in 1951 by Professor Jannie Louw and<br />
since then has grown into a world class centre of excellence with all the modern diagnostic<br />
and treatment facilities needed to treat patients presenting with both benign and malignant<br />
breast pathology.<br />
roote Schuur Hospital (GSH) has a<br />
population of 3.1 million people within<br />
its catchment area which includes the<br />
western part of Cape Town and the<br />
West Coast region. The main referral base includes<br />
44 clinics, of which 35 are City <strong>Health</strong> facilities, and<br />
general practitioners. GSH serves as a safety net for<br />
patients in the Northern Suburbs of Cape Town, other<br />
provinces, and patients beyond our borders.<br />
IN 2016 WE DIAGNOSED 572 NEW<br />
PATIENTS WITH BREAST CANCER.<br />
ALTHOUGH BREAST CANCER IS THE<br />
MOST DEVASTATING DIAGNOSIS, THE<br />
MAJORITY (87%) OF THE 4339 NEW<br />
PATIENTS SEEN IN 2016 PRESENTED WITH<br />
BENIGN BREAST DISEASE.<br />
The clinic is staffed by 2 permanent surgical<br />
consultants, 1 senior registrar / breast fellow, 2<br />
part-time surgical consultants, 2 part-time general<br />
practitioners with an interest in breast diseases, 1<br />
oncology registrar, 1 breast radiologist, 2 cytology<br />
technologists, 2 mammographers and a social worker.<br />
The clinic is open every Friday on the G-Floor in<br />
the outpatient building on the GSH premises. The<br />
clinic offers breast imaging, biopsy and oncology<br />
consultation of newly diagnosed positive breast<br />
cancers. Social and counselling services are also<br />
available on-site to assist newly diagnosed patients.<br />
Francois Malherbe<br />
In 1982 an on-site, real time<br />
cytology service was established<br />
under the guidance of Professor<br />
Dent, Dr Hacking and Dr<br />
Learmonth. To this day it is still one<br />
of only a few such services offered<br />
around the globe. Patients with<br />
palpable breast lumps receive a<br />
same day fine needle aspiration<br />
and cytology results<br />
IT RELIEVES A LOT OF THE ANXIETY<br />
ASSOCIATED WITH WAITING FOR A<br />
RESULT AFTER A BIOPSY FOR A BREAST<br />
LUMP.<br />
Referral criteria include all patients with a clinical<br />
suspicion of breast cancer. Therefore all women or<br />
men older than 30 years with a palpable breast<br />
lump, a spontaneous or bloody nipple discharge,<br />
new onset nipple retraction, ulceration or any<br />
other clinical features that raise the suspicion of a<br />
breast cancer will be attended to on the same<br />
day of referral. We make provision to see 80 new<br />
patients each week but during the busy period<br />
of October to December this number can often<br />
double. If the clinic is overwhelmed by the<br />
number of referrals,we make use of a triage<br />
system and provide the younger patients and<br />
patients with mastalgia without a breast lump<br />
with an elective date, usually within 2 weeks.<br />
15 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
OUR BIGGEST CHALLENGE IS<br />
MANAGING THE BREAST IMAGING<br />
Cyto-technologists hard at work<br />
Our biggest challenge is managing the breast<br />
imaging service with the available resources.<br />
Currently the waiting time for a routine mammogram<br />
IN A PATIENT WHO DOES NOT HAVE<br />
A PALPABLE LUMP STANDS AT 22<br />
WEEKS, WHILE THE WAITING TIME FOR<br />
A ROUTINE ULTRASOUND IS 10 WEEKS.<br />
We have recently acquired an ultrasound machine<br />
in the clinic and young patients are now receiving<br />
an ultrasound examination done by one of the<br />
senior clinicians on the day of their first visit<br />
which is making a significant impact on the<br />
ultrasound waiting times.<br />
With the support of Pink Drive we are trying to reduce<br />
the mammogram waiting times but the sheer volume<br />
of patients seen makes this extremely difficult.<br />
At the Groote Schuur Breast clinic we strive to detect<br />
breast problems at the earliest stage, differentiate<br />
between benign and malignant breast problems, plan<br />
effective management and follow up and counsel<br />
the patient and his/her attendants adequately.<br />
APPOINTMENTS CAN BE MADE VIA<br />
THE GSH OUTPATIENTS CALL CENTRE AT<br />
(021) 404 5566 OR ANY QUERIES CAN<br />
BE DIRECTED TO OUR EMAIL ADDRESS<br />
GSHSURGONC@GMAIL.COM<br />
Nursing Staff in the clinic<br />
Francois Malherbe: Graduated with a FCS(SA) and MMed(UCT) in 2011. Since 2014, after a short period working as a general<br />
surgeon at New Somerset Hospital in Cape Town, he has been back full time at the Groote Schuur Hospital breast and surgical<br />
endocrine unit. His clinical interests are oncoplastic breast surgery, breast cancer research, surgical oncology and endocrine<br />
neoplasms (thyroid, parathyroid, adrenal). Correspondence: francois.malherbe@uct.ac.za<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 16
FOCUS ON<br />
17 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
IT’S IN THE<br />
FOCUS ON<br />
DNA<br />
WOMEN IN HEALTHCARE<br />
Anna Sparaco<br />
What a formative year. This is the year<br />
that the double X chromosome took<br />
traction. As the title of the formidable<br />
Judy Dlamini books states “Equal but<br />
different.” This year saw the introduction of the<br />
Women <strong>Health</strong> Journal and Women in <strong>Health</strong>care<br />
Africa consolidated its footprint.<br />
In this issue, Prof Bev Kamer reflects back on her career<br />
in <strong>Health</strong> Sciences and influences that have made<br />
her who she is. Donne Botha, dynamic manager at<br />
Boston Scientific, gives us some industry perspectives<br />
and touches on stressors. Our resident coach Colleen<br />
Qvist reminds us to be grateful and mindful of our<br />
blessings and achievements.<br />
In a series of 3 financial workshops hosted and<br />
generously supported by Mundipharm, Women in<br />
<strong>Health</strong>care Africa tackled our biggest fear – money<br />
management in our practices. The main concerns<br />
were around understanding tax. Joanne Williams,<br />
from Leading Accounting, summarizes some of the<br />
discussion.<br />
WE FINISH <strong>2017</strong> FEELING THAT SOME STRIDES<br />
HAVE BEEN MADE IN RECOGNIZING<br />
THAT THE XX CHROMOSOME MAKES US<br />
DIFFERENT BUT THAT THESE DIFFERENCES<br />
MAKE US STRONGER. WE ARE DIFFERENT,<br />
BUT WE ARE EQUAL EVEN IF WE ARE LATE<br />
ENTRANTS TO THE PROFESSIONAL SPHERES.<br />
Anna Sparaco<br />
IN 2018 – WATCH THE WIHC-A SPACE –<br />
2 SOCIAL NETWORKING EVENTS AND<br />
SEVERAL WORKSHOPS ARE PLANNED.<br />
WE HOPE YOU ENJOY A GOOD REST<br />
AND HAVE A FESTIVE TIME OVER<br />
THIS DECEMBER AND COME BACK<br />
REFRESHED AND READY TO INCREASE<br />
THE TRACTION AND DEEPEN THE<br />
FOOTPRINT.<br />
Anna Sparaco: HPB practice, Wits Donald Gordon Medical Centre Correspondence: anna.sparaco@surgicalspecialist.co.za<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 18
FOCUS ON<br />
A WOMAN’S TALE:<br />
REFLECTING ON MY PERSONAL<br />
JOURNEY THROUGH A<br />
HEALTH SCIENCES<br />
ACADEMIC CAREER<br />
Beverley Kramer<br />
When I reflect on my life’s journey, as a mother, wife and academic,<br />
the town where I began life comes immediately to mind.<br />
Igrew up in a small East Rand town where mining<br />
was the lifeblood, and my family’s livelihood was<br />
linked to that as well. I am somewhat amazed<br />
that I made it out of that town and progressed in<br />
both thought and action to where I am today. I loved<br />
the town, my childhood there, the friendships that I<br />
developed; I could easily have remained there, lost<br />
forever in a timewarp. My story, however, is not really<br />
about my journey, but rather my mother’s journey, and<br />
how it affected my life.<br />
My mother began life in a mill on a stream in Lithuania,<br />
the daughter of a poor Jewish miller and his wife. She<br />
was one of five children growing up in a beautiful,<br />
but religiously intolerant country. At the age of 15, in<br />
order to escape the malevolent political and religious<br />
climate in Lithuania and the impending advance of<br />
the Nazis, she was sent by her parents on her own,<br />
by boat to <strong>South</strong> Africa. She joined two of her young<br />
siblings who had previously been sent to <strong>South</strong> Africa<br />
and settled here.<br />
The sudden separation from her parents was<br />
traumatic, the trip was long and frightening, but with<br />
her exuberance for life, she made friends on the boat,<br />
and this lessened her fear. My Mom’s schooling had<br />
been interrupted when she was sent to <strong>South</strong> Africa.<br />
She was never able to complete her education and<br />
regretted it all her life. Two years after reaching <strong>South</strong><br />
Africa she was married to<br />
my father, a kind and hardworking<br />
man who had also<br />
escaped from Lithuania<br />
but with his family, to find a<br />
better life in <strong>South</strong> Africa.<br />
My Father was much older<br />
than my Mother and worked<br />
extremely hard. He spent six<br />
and sometimes seven days<br />
Beverley Kramer<br />
a week in his concession<br />
store on the local mine to put<br />
food on the table. More importantly, my Mom wanted<br />
her three daughters to be well-educated, and thus<br />
we hardly ever saw my Dad as he laboured to scrape<br />
together every penny so that one day his daughters<br />
would be able to get a university education. My Mom<br />
cooked, baked and sewed for us.<br />
HER MAXIM WAS “I WILL SCRUB FLOORS<br />
TO GET YOU AN EDUCATION”. MY MOST<br />
VIVID MEMORY OF MY MOTHER’S<br />
THOUGHTS ON EDUCATION WAS:<br />
“STRIVE TO GET THE BEST EDUCATION<br />
THAT YOU CAN. PEOPLE CAN STRIP YOU<br />
OF EVERYTHING, BUT THEY CAN NEVER<br />
STRIP YOU OF YOUR EDUCATION.”<br />
19 *<br />
SOUTH AFRICAN WOMENS HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
I am sure this is a saying that reverberates with many<br />
even today. This left a lasting impression on me, but<br />
only later in life did I realize what this had meant in<br />
the context of her life.<br />
I was deeply saddened for my mother who had been<br />
stripped of her childhood, stripped of her family (she<br />
never found out what had become of her family<br />
who remained in Lithuania once the Nazis invaded),<br />
stripped of her home country and also stripped of<br />
the opportunity to complete her education. Her inner<br />
strength was something that shone through.<br />
My childhood was mostly uneventful, playing in<br />
the street with other children from a variety of<br />
backgrounds. They accepted that my religion was<br />
different to theirs and that I couldn’t play late on a<br />
Friday as my family celebrated the coming of the<br />
Sabbath. Children in those days were accepting and<br />
keen to share their differences. We walked back and<br />
forth to primary school, to the shops, to the homes of<br />
our friends, without the fear of being preyed on by<br />
the scourge of predators who target unsuspecting<br />
children today and remove from them the ability to<br />
have a relaxed childhood. We seldom wore shoes<br />
or had many toys to play with, but life was good. I<br />
remember spending school holidays reading or sitting<br />
on the fence watching cars go by.<br />
THIS IDYLLIC CHILDHOOD WAS<br />
HOWEVER SHATTERED IN MY LATTER<br />
PRIMARY SCHOOL YEARS WHEN I<br />
CAME INTO CONTACT WITH A TEACHER<br />
WHO HATED JEWS, OR PERHAPS HE<br />
HATED EVERYONE, AND JEWS WERE<br />
JUST WITHIN HIS REACH. THIS TEACHER,<br />
THOUGH I SHUDDER AT THE THOUGHT<br />
OF CALLING HIM A TEACHER, TOOK<br />
GREAT PRIDE IN REGULARLY MAKING<br />
ME STAND UP IN CLASS, TO POINT OUT<br />
TO THE STUDENTS THAT I WAS DIFFERENT,<br />
I WAS A JEW. I DIDN’T KNOW MUCH<br />
ABOUT RACISM IN THOSE EARLY YEARS,<br />
BUT I CERTAINLY SOON LEARNED THAT<br />
IT WAS ABHORRENT.<br />
High School in our small town was wonderful. It was<br />
great seeing friends each day. Being introduced to<br />
science was fascinating. I soon found that my love<br />
of books, which had started with reading at the age<br />
of three, had paid off. I had developed an excellent<br />
general knowledge and a yearning to learn. I tried to<br />
absorb as much information as I could, remembering<br />
from my mom that education was everything.<br />
Homework was not easy, as my Mom struggled to help<br />
me and once again, I felt saddened for her as she<br />
struggled with the English language and tried vainly<br />
to help us. My Dad was a whiz at mathematics, but<br />
we had to wait until late at night for his return if we<br />
needed help in that area.<br />
WHAT I SOON LEARNED FROM BOTH OF<br />
THEM THOUGH, WAS THAT THERE WAS<br />
NO SUCH THING AS “CAN’T”. I HAVE<br />
THUS TRIED EVERYTHING FROM ART TO<br />
ANATOMY, FROM PEWTER WORK TO<br />
POTTERY, IN THE REALIZATION THAT WHAT<br />
ISN’T KNOWN, CAN SOON BE LEARNED!<br />
It was customary in those days in our small town to see<br />
gangs of prisoners in chains working on the verges of<br />
the roads or even in the suburbs. These were prisoners<br />
who had been imprisoned for “minor” misdeeds or<br />
who had a short time left before release. All of these<br />
prisoners were black.<br />
My Mom would send us out with mugs of steaming<br />
coffee and liberally buttered bread, which was richly<br />
rewarded with huge smiles and even an occasional<br />
song. When I asked my Mother why she did this, she<br />
would tell me that we should always help those<br />
less fortunate than ourselves, that we should never<br />
discriminate against others no matter what the colour<br />
of their skin or their religion. She would tell me stories<br />
of the horrific discrimination against the Jews by the<br />
Nazis.<br />
SHE TAUGHT ME THE HORRORS OF RACIAL<br />
DISCRIMINATION, AND I LEARNED THAT<br />
IT WASN’T ONLY YOUR RELIGION THAT<br />
COULD CAUSE PEOPLE TO HATE YOU.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 20
FOCUS ON<br />
UNIVERSITY<br />
WAS HEAVEN<br />
With the intention of one day becoming a surgeon, I<br />
left high school and traveled to Johannesburg on the<br />
train to attend Wits University. This change was a total<br />
culture shock to me. The other 1 st year students in my<br />
class were confident, competent and they certainly<br />
knew a lot more about our topics and life than I did. I<br />
was scrutinized as I came into the class everyday……<br />
from the tips of my shoes to the last un-brushed hair<br />
on my head…….after all, dashing backwards and<br />
forwards between Johannesburg’s Park Station and<br />
Wits played havoc with one’s hair!<br />
I traveled on the train, back and forth to Johannesburg<br />
for seven years, in the cold and the heat, and learned<br />
that the train was a perfect place to study life. It was<br />
also where I learned that an umbrella was a girl’s best<br />
friend! Travelling home in the early evening after late<br />
laboratory sessions were slightly hazardous, as mean<br />
guys in long raincoats would often sit too close to one<br />
on the half empty carriages. A tap with a well-placed<br />
umbrella was all it took to get the “gentleman” in<br />
question to vacate the seat.<br />
UNIVERSITY WAS HEAVEN. I HAD<br />
NEVER BEEN EXPOSED TO SO<br />
MUCH INFORMATION, TO SO MANY<br />
INTRIGUING THINGS. THERE JUST<br />
WASN’T SUFFICIENT TIME TO TAKE IT<br />
ALL IN AND ALSO BE EXPOSED TO<br />
STUDENT LIFE. STILL NOT KNOWING<br />
WHETHER I WANTED TO DO MEDICINE<br />
OR SCIENCE, I WAS INTRODUCED TO<br />
THE MARVELS OF THE HUMAN BODY, TO<br />
ANATOMY.<br />
From my first day of dissection, i became fascinated<br />
by the body’s intricacies, by the incredible way<br />
in which it developed, how nerves and vessels<br />
managed to find their way to where they were going<br />
and did so almost always along the same pathways.<br />
Human anatomy and embryology became my<br />
fascination, and all thoughts of surgery vanished.<br />
Having completed my initial degree, i stayed on in<br />
the Wits Medical Department of Anatomy, first as a<br />
student and then as staff.<br />
My initial contact with anatomy in 1968 at the Wits<br />
Medical School on Hospital Hill, started me on a<br />
journey that is yet to be completed. From 1970 while<br />
doing my B.Sc Honours in anatomy, I was appointed<br />
as a Graduate Demonstrator and slowly rose through<br />
the academic ranks until I was appointed as Head<br />
of one Department (General Anatomy in the Wits<br />
Faculty of Dentistry) and then as Head of the Wits<br />
Department of Anatomy and Human Biology in the<br />
Faculty of <strong>Health</strong> Sciences (when the Faculties of<br />
Dentistry and Medicine amalgamated in 1996). This<br />
later became the School of Anatomical Sciences,<br />
which I initially chaired.<br />
Having been Head of Department and School for<br />
17 years, I stepped down to continue with research.<br />
However, always open to a challenge I applied<br />
for and was appointed Assistant Dean: Faculty<br />
of <strong>Health</strong> Sciences in 2008 and retired from this<br />
position at the end of 2016. I continue to teach in<br />
anatomy and undertake research. I am still involved<br />
with international anatomy and anatomists in my<br />
role as President of the International Federation of<br />
Associations of Anatomists.<br />
While all these positions sound wonderful and<br />
glamorous and a step up the academic ladder, they<br />
were paralleled by my even more precious normal life<br />
of being a wife, mother, and grandmother. Each of us<br />
who is a mother and wife will know of the toughness<br />
of the decisions we sometimes need to make, the<br />
challenges which arise when in a full-time position.<br />
AFTER THE BIRTH OF MY FIRST CHILD,<br />
MY STAUNCHEST SUPPORTER OF MY<br />
EDUCATION, MY MOTHER, ASKED<br />
WHETHER IT WASN’T TIME FOR ME TO<br />
GIVE UP WORK AND STAY AT HOME<br />
WITH MY BABIES!<br />
The 1970s were still a time when women had babies<br />
and stayed at home to look after them. I don’t think<br />
that my mother accepted easily that i wanted to work<br />
and be a mother! My years as an academic were<br />
mainly good (I love academic work and research,<br />
21 *<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
MY MOTHER’S WISDOM<br />
enjoy a challenge), often hard and also had some<br />
terrible moments. In my more senior years, I worked 13<br />
hours a day, six days a week. In order to build up the<br />
Department of General Anatomy, to ensure a smooth<br />
transition when the Dental and Medical Anatomy<br />
Departments were amalgamated and to develop<br />
the Research and Postgraduate portfolio in the Wits<br />
Faculty of <strong>Health</strong> Sciences, there was much to do.<br />
The wellbeing of individuals, while bringing two<br />
hugely different groups of staff together, needed<br />
careful management during the amalgamation<br />
of the Medical and Dental Anatomy Departments.<br />
Managing personality differences and a scientific<br />
breech was a harrowing experience when a fallout<br />
occurred between senior scientists in the<br />
School. Dealing with barriers from senior staff, when<br />
one is trying to grow an environment, was just not<br />
comprehensible. These and other challenging<br />
experiences often left me feeling isolated and alone.<br />
I was thankfully able to draw on my inner strength and<br />
optimism, and on the friendship of some wonderful,<br />
wise academics who offered advice and collegiality<br />
during these times. The lessons I had learned from my<br />
mother on racial and gender equality, on fairness and<br />
nurturing, sustained me during these difficult periods.<br />
AS WOMEN, WE TEND TO NURTURE,<br />
TO GROW, TO DEVELOP OTHERS. IF I<br />
SEE THAT SOMETHING NEEDS TO BE<br />
DONE, I GET UP AND DO IT. WERE<br />
OTHER ACADEMICS HELPFUL ALONG<br />
THE WAY? MANY STAFF WERE HELPFUL,<br />
SUPPORTIVE AND COLLEGIAL, BUT<br />
SOME WERE QUITE HORRID. MY<br />
FOCUS AND DRIVE WERE SOMETIMES<br />
CHALLENGED, AND AS I WAS A<br />
WOMAN, IT WAS EXPECTED THAT I<br />
WOULD BACK DOWN.<br />
Somewhere inside me the core of strength derived<br />
from my Mom and two female academics I had<br />
worked with, sustained me. There were a number<br />
of autocratic male academics for, or with, whom I<br />
worked, who couldn’t see academia as a “team”<br />
effort, but rather as a platform for their ego. This<br />
made academia not only hard but also infinitely more<br />
challenging! I was sometimes crucified for speaking<br />
out when I disagreed with what was happening, but<br />
know it was the correct thing to do. I hope that I leave<br />
this courage to “stand up and speak out “as a legacy<br />
to other women in academia.<br />
I MUST PAY TRIBUTE TO WONDERFUL<br />
MENTORS DURING MY ACADEMIC “LIFE”;<br />
KNOWLEDGEABLE AND WARM MEN AND<br />
WOMEN WHO SAW SOMETHING IN ME<br />
THAT THEY FELT WARRANTED NURTURING.<br />
FROM THEM, I LEARNED THE LOVE OF<br />
GROWING PEOPLE. I HAVE HAD GREAT<br />
JOY IN HAVING BEEN A ROLE MODEL<br />
TO SOME, A MENTOR TO MANY AND<br />
A TEACHER TO THOUSANDS. I LOVE<br />
“PAYING FORWARD” AND HAVE DERIVED<br />
ENORMOUS PLEASURE FROM SEEING THE<br />
WONDERFUL ACHIEVEMENTS OF MANY<br />
OF MY STUDENTS AND SOME OF THE<br />
YOUNG STAFF THAT I HAVE MENTORED.<br />
Over the last few years, I have found that academic<br />
collegiality has been changing (is this due to the<br />
pressure which academics experience?), barriers are<br />
being erected just because they can be, teamwork<br />
is not something to which everyone aspires, and<br />
bullying is on the increase, particularly bullying of<br />
senior women. I am particularly concerned about<br />
the latter. As one climbs the academic mountain, the<br />
higher the position, the more “power” is ascribed to<br />
the position. I believe that the higher the position, the<br />
greater is the responsibility to use that “power” wisely.<br />
This translates into building an academic environment<br />
that would benefit all, especially the next generation<br />
of academics.<br />
I REMAIN AN OPTIMIST, HAVE NEVER<br />
LEARNED WHEN TO STOP BANGING MY<br />
HEAD ON THE PROVERBIAL BRICK WALL<br />
AND THINK THAT I HAVE ACHIEVED AT<br />
LEAST HALF OF WHAT I WOULD HAVE<br />
LIKED TO ACHIEVE IN LIFE. MY GREATEST<br />
GIFTS HAVE BEEN MY WONDERFUL<br />
SONS AND MY GRANDCHILDREN, WHO<br />
I HOPE WILL, IN TURN, DERIVE FROM ME<br />
SOME OF MY MOTHER’S WISDOM.<br />
Professor Beverley Kramer: B.Sc.Honours, PhD, FAS (Hon), FAAA, Professor Emeritus, Director: Carnegie-Wits Alumni Diaspora<br />
Programme, President: International Federation of Associations of Anatomy (IFAA), School of Anatomical Sciences, Faculty of<br />
<strong>Health</strong> Sciences, University of the Witwatersrand, Johannesburg, <strong>South</strong> Africa Correspondence: Beverley.kramer@wits.ac.za<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 22
FOCUS ON<br />
SOUTH AFRICAN<br />
TAX AND DNA<br />
Jo-Anne Williams CA (SA)<br />
Just as DNA is a code and contains the key<br />
information for building and maintaining the<br />
organs in our body, similarly our tax legislation<br />
is comprised of various codes and like DNA<br />
you can use it to build and plan your decision around<br />
how tax affects you.<br />
BY GAINING A BASIC UNDERSTANDING<br />
OF THESE SA TAX DNA CODES WE<br />
CAN PLAN FOR TAX AND AVOID<br />
UNDUE STRESS AND PREVENTING<br />
DEVIATIONS FROM THE TAX CODE<br />
(NON-COMPLIANCE) THAT COULD<br />
CAUSE CANCEROUS CELLS, LIKE IN THE<br />
HUMAN BODY, BUT IN THE CASE OF THE<br />
TAX CODES THESE CANCEROUS CELLS<br />
PRESENT AS PENALTIES AND INTEREST.<br />
We shared some of the DNA of <strong>South</strong> <strong>African</strong> tax at<br />
our Tax Workshop, hosted by Women in <strong>Health</strong>care<br />
Africa.<br />
This article highlights some areas in the tax codes<br />
covered in the workshop.<br />
THE PROVISIONAL TAX CODE<br />
PROVISIONAL TAX, as with PAYE, forms part of the<br />
Income Tax Code structure and is important for all<br />
Companies and any individual who earns multiple<br />
sources of income or has not had sufficient PAYE<br />
withheld on a month to month basis. As with DNA<br />
each individual varies slightly from the other but the<br />
base tax code is mostly the same and just needs to<br />
include all the variable financial DNA information<br />
from a tax payer to function properly.<br />
Two important dates for when Provisional Tax would<br />
be paid is typically the last working day in August<br />
and February. The only time this will differ is if your<br />
company has a financial year end other than<br />
Jo-Anne Williams CA (SA)<br />
February. The tax paid for<br />
provisional tax should be<br />
based on an estimate of<br />
what your total Income<br />
Tax will be for that tax year<br />
and it is recommended<br />
you pay it on time, as well<br />
as the correct amount to<br />
avoid any cancerous results<br />
(Penalties and Interest!).<br />
THE INCOME TAX CODE<br />
For a company, the main code which applies to<br />
most companies is an Income Tax Rate of 28%. This is<br />
calculated after taking income (Revenue and other<br />
income) and deducting any valid business expenses.<br />
There is a separate tax code for Small Businesses, but<br />
as most services in healthcare are provided by the<br />
owner or Practitioner, not all these businesses will<br />
be able to apply this tax code to their business, as<br />
with DNA each individual is different and need to<br />
be assessed to see if their particular financial DNA<br />
(information) matches up to a certain income tax<br />
DNA code.<br />
FOR INDIVIDUALS, THE INCOME TAX<br />
DNA CODE IS MADE UP OF SEVERAL<br />
TAX PERCENTAGES TO APPLY TO AN<br />
INDIVIDUAL’S TAXABLE INCOME, DUE<br />
TO SOUTH AFRICA’S TIERED TAX RATE<br />
SYSTEM FOR INDIVIDUALS. AS SUCH<br />
A LOT MORE INFORMATION FROM A<br />
PERSON FINANCIAL DNA IS REQUIRED<br />
TO DETERMINE WHICH AND HOW THE<br />
SA INCOME TAX DNA CODE WOULD<br />
BE APPLIED TO THEM TO ALLOW FOR<br />
PROPER PLANNING AND AVOIDING<br />
ANY DEVIATION FROM THE SA INCOME<br />
TAX CODE.<br />
23 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
SA TAX<br />
DNA<br />
THE VAT CODE<br />
When looking at the VAT (Value Added Tax) Code,<br />
we discussed the various aspects around the VAT<br />
DNA code such as when it becomes mandatory to<br />
apply for VAT and how to apply this VAT DNA code in<br />
the structure of a medical practice. Although you can<br />
voluntarily apply the VAT code if you generate sales<br />
above R50,000 it becomes mandatory to register for VAT<br />
when your business is anticipating generating income<br />
of R1 million or more during any 12-month period.<br />
deduction of VAT charged by other business for goods<br />
or services rendered by them to your business, usually<br />
in a bi-monthly cycle.<br />
EMPLOYEE TAX CODES<br />
When hiring staff (including yourself in the case of<br />
a company), there are 3 main Employee Tax codes<br />
which will form part of the employees tax DNA for your<br />
practice, a monthly payment due to SARS by no later<br />
than the 7th of each month.<br />
IT MUST HOWEVER BE NOTED THAT<br />
IN APPLYING THIS VAT DNA CODE<br />
WITHIN YOUR BUSINESS THERE ARE<br />
A LOT OF COMPLEXITIES THAT NEED<br />
TO BE COMPLIED WITH, AND IT IS<br />
RECOMMEND TO HAVE A VAT CODE<br />
SPECIALIST, NAMELY AN ACCOUNTANT<br />
OR TAX PRACTITIONER, TO ASSIST IN<br />
PREVENTING DEVIATIONS FROM THE<br />
VAT CODE THAT COULD LEAD TO<br />
CANCEROUS RESULTS (PENALTIES AND<br />
INTEREST) DUE TO THE INCORRECT<br />
INFORMATION AND THE INCORRECT<br />
APPLICATION OF THIS VAT DNA TO THE<br />
CIRCUMSTANCES OR FINANCIAL DNA<br />
IN YOUR BUSINESS.<br />
A high-level view, the VAT (Value Added Tax) code is<br />
a rate of 14% which needs to be charged on sales/<br />
services rendered to patients, which is then paid<br />
over to the <strong>South</strong> <strong>African</strong> Revenue Services after the<br />
Jo-Anne Williams CA (SA): Co-Founder and Tax Director at Leading . Edge Accounting, specialising in accounting and tax for<br />
Small and Medium size businesses. Correspondence: Please contact the relevant sub-editor as well as cc the Editor-in-<br />
Chief for more information.<br />
THE FIRST OF THE EMPLOYEE TAX CODE IS PAYE<br />
(PAY AS YOU EARN), PAYE is calculated using the<br />
Individual Tax Rate table. It is determined by adding<br />
any salary and benefits (medical aid contributions,<br />
use of a motor vehicle, ect…) and then applying the<br />
rates from the Individual Tax code to the total of these<br />
amounts.<br />
THE SECOND EMPLOYEE TAX CODE IS UIF<br />
(UNEMPLOYMENT INSURANCE FUND), which<br />
is payable for anyone employed and working more<br />
than 24 hours a month. The rate applied is 2%, where<br />
1% is deducted from the employee’s salary and the<br />
other 1% is paid by the employer (limits are applied<br />
to the total amount that can be deducted for UIF).<br />
THE THIRD EMPLOYEE TAX CODE IS SDL (SKILLS<br />
DEVELOPMENT LEVY), this applies to businesses<br />
where the total salaries are anticipated to be more<br />
then R500 000 in the next 12 months. The application<br />
of the SDL code amounts to 1% being payable by<br />
the employer on the total amount in salaries paid<br />
per employee.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 24
FOCUS ON<br />
BE BOLD<br />
FOR CHANGE <strong>2017</strong><br />
Donne Botha<br />
I recently found myself reflecting on a voyage back in time thinking<br />
about the many wonderful women who have come before us and<br />
continue to make a difference and strive for the equality of all women.<br />
They have endured hardship and sacrifice<br />
for the freedom and upliftment of others,<br />
they have relentlessly pursued and acted<br />
with courage to overcome ethnic, religious,<br />
educational and gender prejudice. I couldn’t help<br />
but giggle as I traveled through the 60s – when<br />
females devoted their life to their husbands, children,<br />
and homemaking. The better you perform in your<br />
position, the cuter you were perceived. Now please<br />
don’t misunderstand me – being a devoted wife,<br />
mother and homemaker is very noble and something<br />
many of us strive to perfect in part, but it should be<br />
out of choice and not the expectation. Talking to<br />
many women today, it is clear that women desire<br />
different things in life and cannot be put in a box – the<br />
opportunity to reach life goals, whether it be enjoying<br />
or excelling at a hobby, choosing to accomplish a<br />
physical or spiritual purpose, attaining a promotion or<br />
high power position or devoting their time and life to<br />
their families and caring for loved ones.<br />
So luckily much has progressed in the workplace since<br />
the 1960s and women have far more choice since<br />
the beginning of time but how far have we really<br />
come? it is estimated that women make up 45% of<br />
the workforce yet hold only 9% of CEO positions and<br />
just 21% of leadership jobs globally.<br />
We know that globalization, building key capabilities,<br />
improved profits, customer engagement, high<br />
performance and fueling growth are just a few<br />
examples of corporate buzz words every time we<br />
walk into the boardroom and so if we are to achieve<br />
these goals, we need to recognize that gender<br />
diversity and inclusion matters and how we lead<br />
in this transformation will make all the difference to<br />
us and future generations. Studies have shown that<br />
companies with top quartile<br />
representation of women<br />
in executive positions<br />
perform significantly better<br />
financially than those with<br />
no women.<br />
It is this business issue and<br />
opportunity supported by<br />
Boston Scientific and being<br />
Donne Botha<br />
inspired by our daughters to<br />
be more and do more in creating equal opportunity<br />
for women in leadership, which led to the start of<br />
our women in leadership council in <strong>South</strong> Africa. Our<br />
goal is to create an inclusive environment to attract,<br />
develop and retain female talent at all levels and<br />
help them achieve their career best.<br />
We realize that the journey is not without barriers.<br />
Let’s be honest; we’re trying to change 4 million<br />
years of evolution! Finding and managing solutions<br />
to dealing with unconscious/conscious bias, work-life<br />
balance pressures, exposure to role models, gender<br />
readiness perceptions and networking opportunities<br />
are just a few examples of what we need to embrace,<br />
however if we seek to find the opportunity for every<br />
barrier and arm ourselves with the secrets of some of<br />
the most influential women of yesterday and today<br />
like courage, collaboration, embracing differences,<br />
perseverance, networking platforms and a passion<br />
for making a difference and self-belief, then nothing<br />
can stop us.<br />
Our message is simple – we are equal but different.<br />
We don’t want to be treated with special conditions<br />
and privilege; we want to be treated with fairness and<br />
equality based on our skills and capabilities.<br />
Donne Botha: Business Unit Manager, Urology & Pelvic <strong>Health</strong> at Boston Scientific. Correspondence: Please contact the<br />
relevant sub-editor as well as cc the Editor-in-Chief for more information.<br />
25 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
STOPPING THE<br />
BLUR<br />
Colleen Qvist<br />
I am sure that you have been on a train or car that is traveling so fast that<br />
all you can see out the window is a blur. The houses, buildings, people,<br />
animals and trees flow into each other.<br />
To many of us, this is what life feels like as we<br />
focus on a destination and the rest blurs into<br />
a grey streak.<br />
We have become so goal orientated. Our days<br />
and nights are taken up with the constant quest for<br />
success. The promotion, buying the new car, reaching<br />
a specific salary or weight, getting the kids through<br />
Grade 4 or 8 or 12 or even the number of Facebook<br />
friends all occupy our minds.<br />
We are even focused on getting to the end of the<br />
year so that we can turn over that last page and start<br />
the next year.<br />
WE ARE SO CAUGHT UP IN THE<br />
DESTINATION AND THE GOAL THOUGH,<br />
THAT OUR TODAY AND THE MAGIC<br />
MOMENTS IN THE NOW ARE LOST.<br />
WE CANNOT GET THEM BACK, AND I<br />
WONDER IF THIS IS WHY IT FEELS LIKE<br />
TIME IS RUSHING PAST SO QUICKLY? WE<br />
ARE SITTING IN OUR “TRAINS” NOT EVEN<br />
AWARE OF THE BLUR AS WE FOCUS ON<br />
THE DESTINATION.<br />
If all of this focus is making you feel empty and you<br />
would like to stop to smell the coffee and to drink it<br />
with the people who matter, I would like to suggest<br />
two powerful interventions.<br />
Colleen Qvist<br />
MEDITATION<br />
As soon as I mention<br />
meditation to my coaching<br />
clients, they automatically<br />
reply that they do not know<br />
how to do meditation and I<br />
am sure they are picturing<br />
sitting on a mat in a yoga<br />
pose. I am also told that<br />
they cannot do silence or<br />
that they do not know how<br />
to empty their minds.<br />
WE ARE DEFINED BY THE RULES OR OUR<br />
PERCEPTION OF THE RULES.<br />
A meditation programme that has made a massive<br />
difference in my life is Insight Timer. My daughter<br />
introduced me to the app at the end of last year,<br />
and it is downloaded on my cell phone. It has a<br />
whole array of different types of meditations of<br />
varying lengths, guided, silence, musical, nature and<br />
I have enjoyed choosing one, and if I do not like that<br />
particular one, I stop it and find a new one.<br />
I have seen the difference in me (and my daughter)<br />
as I have meditated most days. I have been aware<br />
that my thoughts and the shopping list do not<br />
necessarily leave my thoughts. Instead, I picture a<br />
river, and I allow those thoughts to float on past.<br />
27 *<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
I WOULD LIKE TO ENCOURAGE YOU TO<br />
EXPERIMENT WITH MEDITATION AND<br />
TO DO WHAT MAKES YOU FEEL GOOD.<br />
LET’S SKIP THE MANUAL WITH THE 100<br />
WAYS TO DO IT SOMEONE ELSE’S WAY.<br />
GRATITUDE<br />
My home has a gratitude jar in the kitchen. It is a large<br />
see-through jar and next to it are coloured pieces of<br />
paper and a pen. We write something we are grateful<br />
for and pop it into the jar. Even my daughter, who<br />
does not live here during the week comes home on<br />
weekends to fill in her gratitude slips.<br />
On 31 December we gather as a family and unpack<br />
the jar and read what we have written. You will be<br />
amazed at how many pieces of paper can fit into a<br />
jar. It is a reminder of all we had to be grateful for and<br />
that the year was indeed filled with blessings. Have<br />
you noticed how people tend to decide by the end<br />
of the year that the year was BAD and that it is time<br />
for a new one? The sad thing is the following year will<br />
also be BAD, and they will need another one.<br />
WE HAVE PLACED THE OLD GRATITUDE<br />
JAR FROM THE PREVIOUS YEAR IN THE<br />
LOUNGE, AND IT IS AN ORNAMENT<br />
WITH THE PURPOSE TO REMIND US<br />
THAT GRATITUDE IS AN AMAZING<br />
WAY TO ATTRACT MORE THINGS TO BE<br />
GRATEFUL FOR. IN THE QUEST FOR THE<br />
DESTINATION, WE SO OFTEN FORGET<br />
WHAT WE HAVE ALREADY, AND I AM<br />
HUMBLED BY THE SAYING “BE MINDFUL<br />
THAT WHAT YOU ALREADY HAVE, OTHER<br />
PEOPLE ARE PRAYING FOR.”<br />
Making a lasting impact in our lives depends on us<br />
introducing new habits, and this takes repetition<br />
and reinforcement. Do send me the pictures of your<br />
gratitude jar and share stories of how meditation<br />
helps you. You may have other<br />
methods to help you slow down to<br />
notice the magical moments, and<br />
you are welcome to share these too.<br />
Colleen Qvist: Business and Personal<br />
Coach, Facilitator and Speaker,<br />
Founder of CQ Consulting and<br />
The Pink Diamond Club.<br />
Gauteng Chair for COMENSA<br />
and serves on the Women in<br />
<strong>Health</strong>care Africa Exco.<br />
Correspondence: colleen@cqconsulting.co.za<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 28
FOCUS ON<br />
29 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
HOW SOPHROLOGY:<br />
HELPS PREGNANCY<br />
A WOMAN’S JOURNEY<br />
BEFORE, DURING & AFTER<br />
Ishana Maharaj<br />
OBSTETRICS & GYNAECOLOGY<br />
Many women have a deep need or<br />
sometimes a secret wish to start a family.<br />
It’s a magical moment to become a<br />
loving mother and experience the pure<br />
unconditional love of her own baby.<br />
However for some women, falling pregnant has its<br />
challenges in today’s demanding environment,<br />
largely due to career pressures combined with<br />
the rigors of hectic daily lives. Adding workplace<br />
obstacles, it becomes a challenge for women to<br />
cope.<br />
SOPHROLOGY IS A SIMPLE, HOLISTIC<br />
APPROACH AIMED AT BRINGING THE<br />
MIND, BODY & SPIRIT INTO HARMONY<br />
Comprising of effective exercises, breathing<br />
techniques, visualization, bits of meditation and many<br />
additional techniques, this leads to optimal health<br />
and wellbeing. Sophrology is beneficial to all stages<br />
of pregnancy (i.e. Pre-Natal, Delivery & Post-Natal). It<br />
can be done in various sitting positions, standing or<br />
lying down if fatigued.<br />
PRE-NATAL STAGE<br />
“I am really trying to fall pregnant …”<br />
Ishana Maharaj<br />
The elements of stress,<br />
burnout, tension and anxiety<br />
together with an unhealthy<br />
diet, impacts the body and<br />
results in a less desirable<br />
lifestyle. When the body<br />
endures this long-term<br />
stress, complications may<br />
arise, and this does not help<br />
women who want to fall<br />
pregnant.<br />
But there’s hope, as Sophrology comes to the rescue.<br />
There could be various medical reasons why a woman<br />
has difficulties in falling pregnant. Once identified,<br />
solutions or options could be recommended by a<br />
doctor.<br />
Whatever solution or changes are required to reach<br />
this goal, Sophrology helps in the following ways:<br />
• Prepares the body for pregnancy – i.e. physically,<br />
mentally and spiritually<br />
• Releases stress, tension & anxiety from the body<br />
• Supports you through the possible ups and downs<br />
of IVF and helps you build resilience<br />
• Harmonizes/Activates/Stimulates all cells, organs,<br />
bones, muscles, glands and systems of the body<br />
• Keeps you in a calm, peaceful, relaxed state<br />
• Exercises are customized to focus on an individual’s<br />
needs<br />
• Enhances & improves ALL systems of the body:<br />
i.e. Reproductive; Immune/Lymphatic; Endocrine;<br />
Digestive; Nervous; Cardiovascular; Renal &<br />
Muscular Systems<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 30
FOCUS ON<br />
SOPHROLOGY COMES TO THE RESCUE<br />
DELIVERY STAGE<br />
You will feel prepared for any type of situation<br />
that might emerge on the day of the birth, and<br />
feel equipped to deal with difficult situations<br />
• Creating a better connection with baby in the<br />
womb through practicing visualization exercises<br />
• Supporting the digestive system, especially during<br />
heartburn, constipation or cramping<br />
• Assisting with & managing pain endurance<br />
• Staying focused on yourself & baby and<br />
embracing each step of pregnancy consciously<br />
“I am pregnant! However, I am anxious<br />
and scared…”<br />
Whether it’s your first or fourth baby to be born, each<br />
woman’s journey is unique. Some women worry or<br />
panic about whether they are able:<br />
• to carry to full term of pregnancy,<br />
• scared of the birth procedure,<br />
• Helping to visualize your baby’s journey into the<br />
world<br />
• Boosting your confidence and taking the time to<br />
integrate the changes you are going through<br />
• Helping to remove your fears<br />
POST-NATAL STAGE<br />
• or how to cope with certain health complications<br />
during their pregnancy<br />
During the 9 months of pregnancy, a woman comes<br />
to terms with becoming a mother. In the real world,<br />
there is never enough time to look after ourselves.<br />
We need to be aware of the adverse effects of stress<br />
on the body.<br />
OUR EXTERNAL APPEARANCE CAN<br />
ALSO BE A SOURCE OF WORRY.<br />
SOPHROLOGY ALLOWS PREGNANT<br />
WOMEN TO ACCEPT AND EMBRACE<br />
THIS SPECIAL TIME OF LIFE AND FIND<br />
IT MEANINGFUL RATHER THAN SCARY.<br />
IT ENABLES A PREGNANT WOMAN’S<br />
FOCUS TO SHIFT FROM THE WORRY<br />
ABOUT HER SHAPE TO FEELING<br />
EMPOWERED BY THE LIFE WITHIN.<br />
WE MUST NOT FORGET THE ROLE<br />
OF FATHERS AS WELL, WHO MAY BE<br />
EXPERIENCING STRESS AND ANXIETY<br />
DURING THEIR PARTNER’S PREGNANCY.<br />
Sophrology supports them through this process<br />
of transition, learning about their partner’s body<br />
changes and welcoming the arrival of the baby.<br />
Sophrology helps by:<br />
• Creating a more relaxed pregnancy & positive<br />
delivery – by doing various breathing techniques.<br />
“Motherhood …I am always tired,<br />
experience fatigue and<br />
sometimes feel depressed …”<br />
Giving birth or being a mum can be the most<br />
phenomenal and wonderful gift in life, however, your<br />
body has been through a huge physiological roller<br />
coaster and it needs time to recover. Many women<br />
feel tired, overwhelmed and frustrated for they cannot<br />
cope as well as they did before they had children.<br />
Sophrology helps you achieve that deep state of<br />
relaxation which is called “sophroliminal state”. This<br />
occurs when the alpha brain waves kick in to provide<br />
a sense of well-being.<br />
Time is precious, especially when you have to establish<br />
a new routine with baby. Sophrology offers simple and<br />
31 *<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
effective techniques that can be practiced regularly<br />
for 20 min at any time, in the comfort of your home.<br />
The exercises offer immediate relief. Sophrology can<br />
help you to:<br />
• Improve & speed up your recovery process after<br />
birth<br />
• Balance your emotions and mood swings related<br />
to hormonal changes<br />
• Accept the transition and improving your quality<br />
of life<br />
• Sleep better so that you feel more energized and<br />
alert<br />
• Deal positively with family, expectations, beliefs<br />
etc.<br />
• Bond with your baby and feel motivated/positive<br />
in your new role<br />
IN CONTINENTAL EUROPE DOCTORS<br />
RECOMMEND SOPHROLOGY AS AN<br />
EFFECTIVE RELAXATION AND SELF-<br />
DEVELOPMENT TECHNIQUE TO NOTABLY<br />
HELP DEAL WITH PREGNANCY, PREPARE<br />
FOR BIRTH, DEAL WITH ANXIETIES AND<br />
LACK OF SLEEP.<br />
IT CAN HELP YOU PREPARE FOR BIRTH<br />
BY ENABLING YOU TO ACCESS YOUR<br />
INNER RESOURCES, REINFORCING<br />
CONFIDENCE AND POSITIVITY.<br />
SOPHROLOGY CAN HELP YOU EMBRACE<br />
THE EXPERIENCE OF PREGNANCY, BIRTH<br />
AND MOTHERHOOD ACCORDING TO<br />
YOUR PERSONAL VALUES.<br />
Ishana Maharaj: Sophrology Practitioner - Having worked in<br />
the corporate world for over 18 years, I resigned as a Project<br />
Manager to relocate to Switzerland with my family, for a few<br />
years. During my time in Geneva, I discovered Sophrology,<br />
and was fascinated by its history, and widespread adoption<br />
in Switzerland, France, Spain and the UK over the last 55<br />
years. Having studied Sophrology at a leading institution in<br />
Geneva, Switzerland, I personally experienced the benefits<br />
of this journey. Returning to my home in <strong>South</strong> Africa as a<br />
Sophrology Practitioner, being a Mum of 3 children (son-<br />
17yrs & twin girls 10yrs of age), I felt blessed with a “gift”.<br />
A special gift to share with people of <strong>South</strong> Africa. My<br />
ultimate passion is to create an awareness, help, support,<br />
share my knowledge and experiences of this phenomenal<br />
wellness technique, with people. As the first Sophrologist in<br />
Johannesburg, my practice resides in Eagle Canyon Business<br />
Centre, Eagle Canyon Estate, Honeydew.<br />
Correspondence: ishana@sophrology.co.za;<br />
www.sophrology.co.za; Cell: 0827994311.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong> * 53<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 32
FOCUS ON<br />
FAT<br />
G R A F T I N G<br />
35 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
THE ROLE OF<br />
FAT GRAFTING<br />
IN AESTHETIC SURGERY<br />
Marisse Venter<br />
AESTHETICS & RECONSTRUCTION<br />
The concept of transferring fat from one area of the body to another has<br />
been around for a very long time.<br />
Living fat tissue is harvested from one area of<br />
the body, purified and transferred to another<br />
to add volume. Ideally, the fat is harvested by<br />
liposuction in an area of unwanted or excess,<br />
e.g., the belly, love handles or thighs, it is then carefully<br />
injected into an area where the main aim is to correct<br />
a volume deficit.<br />
Fat grafting is used in breast surgery and facial<br />
rejuvenation in many ways. Volume replacement<br />
and correction of contour deformities can be used<br />
for breast augmentation, partial breast resection,<br />
implant-related contour deformities, radiation injury,<br />
scar management and facial rejuvenation, in the<br />
same way “Polly-filler” is used to smooth dents and<br />
irregularities.<br />
Recent literature suggests that fat has numerous<br />
added advantages. Fat is rich in pro-inflammatory<br />
cytokines, growth factors, stem-cells and has multiple<br />
cellular functions.<br />
THUS THE BENEFITS OF FAT STRETCH FAR<br />
BEYOND WHAT THE NAKED EYE MAY SEE<br />
AFTER THE PHYSICAL IMPROVEMENT IS<br />
NOTICED. OFTEN THE SURGEON AND<br />
PATIENT COMMENT ON AN IMPROVED<br />
SKIN TEXTURE IN THE AREA WHERE FAT<br />
GRAFTING WAS DONE.<br />
Marisse Venter<br />
The effect of adipose-derived<br />
stem cells on breast tissue in<br />
patients with previous breast<br />
cancer is not entirely known.<br />
The literature has established<br />
that fat grafting does not<br />
interfere with the ability to<br />
detect malignant changes<br />
in breast tissue nor do the<br />
stem cells cause cancer cells<br />
to proliferate or form new<br />
cancers.<br />
THE EXACT EFFECTS OF FAT GRAFTING<br />
WILL ONLY BE KNOWN OVER SOME<br />
YEARS TO COME. WE HAVE SAFELY BEEN<br />
PERFORMING FAT GRAFTING OVER THE<br />
PAST TEN YEARS WITH NO ADVERSE<br />
EFFECTS.<br />
According to the American Association of Plastic<br />
Surgeons: “The existing evidence suggests<br />
autologous fat grafting as an effective option in<br />
breast reconstruction following mastectomy while<br />
demonstrating moderate to significant aesthetic<br />
improvement. Also, the available evidence also<br />
cites autologous fat grafting as a useful modality<br />
for alleviating post mastectomy pain syndrome.<br />
Furthermore, the evidence suggests autologous fat<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 36
FOCUS ON<br />
grafting as a viable option for improving the quality<br />
of irradiated skin present in the setting of breast<br />
reconstruction.”<br />
Usually, 40% of the injected fat cells may not survive.<br />
Thus additional fat grafting may be required<br />
several months later. However, the 60 -70% of the fat<br />
transplants that do survive will be permanent. It is<br />
not uncommon for a patient to receive multiple fat<br />
grafting procedures.<br />
Fat grafting is most commonly performed in theater<br />
under general anesthesia, and occasionally may be<br />
performed as an outpatient procedure in the rooms.<br />
THE ADVANTAGES OF FAT GRAFTING ARE:<br />
• using your own tissue<br />
• fat is removed from an unwanted area<br />
• both the liposuction and the fat injections are<br />
done with local anesthetic<br />
• It is not a significant surgical procedure and<br />
involves only a few days recovery in most cases<br />
• many women report that a fat-graft reconstructed<br />
breast has sensation and feels soft, much like a<br />
natural, unreconstructed breast<br />
• There is an improvement in the overlying skin<br />
texture, skin quality, and subcutaneous<br />
component.<br />
THE DISADVANTAGES OF FAT GRAFTING ARE:<br />
• No significant clinical studies with long-term follow<br />
up have been done on fat grafting, but small<br />
studies report good results, i.e. there is a currently<br />
ten-year data out.<br />
• The injected fat may be reabsorbed by the body<br />
you may lose some volume over time<br />
• Some of the fat injected into the breast area may<br />
die, which is called “necrosis” (symptoms of<br />
necrosis may include pain and bleeding, the skin<br />
turning dark blue or black, numbness, fever, and<br />
sores that ooze a bad-smelling discharge or pus)<br />
• Contour deformities may occur at the liposuction<br />
site and have all the complications associated<br />
with liposuction<br />
• Asymmetry and irregularity between the sides<br />
lip-filled<br />
• Prolonged swelling & bruising in facial area<br />
• 1% incidents of blindness have been reported<br />
which is permanent<br />
THE PROCEDURE<br />
This is mostly performed under a general anesthetic,<br />
although occasionally the procedure may be<br />
performed under local anesthetic. The reconstructive<br />
surgeon may mark the appropriate areas for<br />
liposuction before the procedure. Small (5mm)<br />
access incisions are made for liposuction. These<br />
small incisions are closed by absorbable suture<br />
material. Liposuction may be done either from the<br />
lower abdomen, thighs, flanks or buttocks. The fat<br />
is prepared and injected into the desired area by<br />
small, precise injections. The liposuction area may be<br />
strapped post operatively to maintain compression.<br />
One would have to stay in the hospital for a day post<br />
surgery. Antibiotics and pain tables will be given<br />
to take home. Recovering from fat filling is mostly<br />
swift and uneventful as an isolated fat fill is a minor<br />
procedure. There may be some oozing of clear fluids<br />
from the liposuction areas.<br />
WHAT YOU SHOULD KNOW<br />
The most common complications seen in fat grafting<br />
is prolonged swelling and bruising at the injection<br />
site. The swelling is less of a problem in the breast<br />
but may cause significant distress if facial swelling<br />
remains for a long time.<br />
The amount of fat that survives is unpredictable. The<br />
current estimation is that 40% of the fat volume will be<br />
lost. The volume deficit depends on numerous, not as<br />
yet openly identifiable factors, e.g. increase metabolic<br />
rate, medication, etc.<br />
ANOTHER, PERHAPS LESS KNOWN<br />
COMPLICATION OF FAT GRAFTING IS<br />
THE TENDENCY OF THE FAT VOLUME TO<br />
INCREASE AS BODY WEIGHT INCREASES.<br />
ONCE AGAIN THE DIFFICULTY IS<br />
MOST TROUBLESOME IN THE FACE AS<br />
LOCALIZED FAT POCKETS MAY ARISE<br />
RESULTING IN, E.G. BAGS UNDER THE<br />
EYES. THE FAT COLLECTIONS CAN<br />
BE MANAGED BY FAT REMOVAL OR<br />
LIPODISSOLVE.<br />
As the use of fat grafting is increasing, numerous<br />
added effects of fat grafting are becoming evident.<br />
Fat grafting has shown to decrease fine lines and<br />
wrinkles, improve skin texture, lighten pigmentation<br />
and forms new collagen and elastin, thus delaying<br />
the aging process.<br />
DR MARISSE VENTER: Plastic and Reconstructive Surgeon at Netcare Milpark Hospital. She has a special interest in breast<br />
reconstruction and cosmetic surgery. Correspondence: dr.mventer@gmail.com<br />
37 *<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
THE LOW DOWN<br />
HEALTH AND LIFESTYLE<br />
Inge Kriel<br />
VACCINATION RATES HAVE DECREASED IN RECENT YEARS,<br />
LARGELY IN RESPONSE TO THE ANTI-VAXXER MOVEMENT.<br />
accination rates have decreased in recent<br />
years, largely in response to the anti-vaxxer<br />
movement. Social media has contributed<br />
to fear mongering in the general<br />
population, with patients reporting vaccine-related<br />
side-effects on a variety of social media platforms<br />
and encouraging other parents not to vaccinate<br />
their children.<br />
DR ANDREW WAKEFIELD, THE INFAMOUS<br />
MEDICAL GASTRO-ENTEROLOGIST<br />
WHO PUBLISHED HIS FINDINGS IN THE<br />
THE LANCET THAT THE MMR VACCINE<br />
IS RELATED TO AUTISM, HAS SINCE<br />
BEEN STRUCK OFF THE ROLL AS HIS<br />
METHODOLOGY WAS QUESTIONABLE<br />
AND HE DID NOT DECLARE A POTENTIAL<br />
CONFLICT OF INTEREST. HIS ARTICLE<br />
WAS WITHDRAWN FROM THE JOURNAL<br />
AS HE WAS WIDELY DISCREDITED.<br />
Unfortunately, the damage has been done – his article<br />
has fuelled the anti-vaxxer movement to the point<br />
that the MMR vaccine is no longer in production in<br />
some areas due to lack of demand. There have been<br />
recent outbreaks of measles and diphtheria in <strong>South</strong><br />
Africa, most likely due to poor uptake of vaccinations.<br />
Patients place their trust in health care professionals<br />
– they trust us to guide them in making decisions<br />
regarding their health. However, when one of our own<br />
publish their unverified findings in an eminent medical<br />
journal, patients are left bewildered and confused as<br />
to whom to trust.<br />
If a medical doctor is telling<br />
them not to vaccinate, then<br />
they trust that it would be in<br />
their best interests to follow<br />
this advice.<br />
Furthermore, patients have<br />
access to scientific journals<br />
without the requisite<br />
training in interpretation of<br />
Inge Kriel<br />
statistics. This creates a very<br />
dangerous situation in which patients make ill-advised<br />
decisions based on dodgy statistics.<br />
All health care practitioners, whether generalists or<br />
specialists, should be doing more to promote uptake<br />
of vaccinations. Vaccinations should be discussed at<br />
every consultation. A balanced approach should be<br />
taken when discussing vaccines – the benefits and the<br />
potential adverse effects both deserve equal attention.<br />
SO WHAT SHOULD WE BE FOCUSING ON<br />
DURING CONSULTATIONS WITH REGARDS TO<br />
VACCINATIONS?<br />
Firstly, we should be reassuring patients that multiple<br />
large randomised controlled trials have failed to<br />
demonstrate a causal relationship between the MMR<br />
vaccine and autism.<br />
Secondly, while we are obliged to discuss potential<br />
side-effects of vaccines, we should spend an equal<br />
amount of time discussing the potential negative<br />
consequences of not being vaccinated.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 38
FOCUS ON<br />
I WAS IN ICU FOR A WEEK AFTER<br />
CONTRACTING MENINGOCOCCAL<br />
SEPTICAEMIA DURING MY DAYS AS A<br />
MEDICAL STUDENT. MENINGOCOCCAL<br />
SEPTICAEMIA HAS A MORTALITY OF<br />
100% IF LEFT UNTREATED, WITH A<br />
MORTALITY RATE APPROACHING 50%<br />
EVEN IF APPROPRIATE TREATMENT<br />
IS TIMEOUSLY COMMENCED. THE<br />
INFECTIOUS DISEASE SPECIALIST<br />
MANAGING MY CASE TOLD MY FAMILY<br />
THAT ONLY TWO OUT OF THE FIFTY<br />
PATIENTS WITH MENINGOCOCCAL<br />
SEPTICAEMIA THAT HE HAD TREATED,<br />
SURVIVED. I WAS ONE OF THEM.<br />
Meningococcal septicaemia is a vaccine-preventable<br />
illness. Menactra, the vaccine recently launched,<br />
protects against four of the most common strains of<br />
Neisseria meningitides. However, when I did a quick<br />
survey amongst parents at my son’s day-care, only<br />
one or two parents even knew that Menactra existed.<br />
FURTHERMORE, I HAVE NOTICED IN<br />
GENERAL PRACTICE THAT PATIENTS (AS<br />
WELL AS HEALTH CARE PROFESSIONALS)<br />
ARE MISINFORMED ABOUT HOW AND<br />
WHEN VACCINATIONS CAN BE GIVEN.<br />
Vaccines should be delayed in moderate to severe<br />
acute infectious conditions (with or without fever),<br />
but there is no contraindication to vaccination in the<br />
presence of mild illness (even with fever). Mild acute<br />
illnesses include upper respiratory tract infections,<br />
colds, otitis media and mild diarrhoea. Delay in<br />
vaccination of patients with mild illness may hamper<br />
vaccination uptake.<br />
Other conditions incorrectly perceived as vaccination<br />
contra-indications include: previous erythema/<br />
oedema at injection site or low-grade/moderate<br />
fever after previous immunisation, current antibiotic<br />
therapy, and history of non-vaccine allergies.<br />
Administration of the varicella vaccine is not contraindicated<br />
for individuals who have a family member<br />
or household contact with immunodeficiency, or in<br />
the setting of HIV infection where the patient only has<br />
mild symptoms. Hepatitis B can safely be given during<br />
pregnancy and in the setting of auto-immune disease.<br />
Confusion arises with regards to co-administration<br />
of vaccines. Vaccinations may be inappropriately<br />
delayed due to lack of knowledge regarding which<br />
vaccinations can safely be given at the same visit.<br />
As a general rule, most vaccines can safely be coadministered.<br />
An exception to this rule is that the<br />
pneumococcal vaccine (PCV13) should not coadministered<br />
with Menactra in patients with functional<br />
or anatomic asplenia. PCV13/DTP should not be coadministered<br />
with influenza vaccination as there is<br />
an increased risk of febrile seizures. Live parenteral<br />
vaccines (MMR, MMRV, Varicella, Zoster, and yellow<br />
fever) may be administered simultaneously. If not<br />
administered on the same day, they should be given<br />
at least four weeks apart in order to eliminate potential<br />
interference (the first vaccine may interfere with the<br />
antibody response of the second vaccine). Every<br />
opportunity should be taken to ensure simultaneous<br />
administration of vaccinations, especially in children,<br />
as this increases the likelihood that patients will be<br />
fully immunised according to schedule.<br />
Combination vaccinations are preferred over single<br />
component vaccines. One notable exception is the<br />
MMRV vaccine in children 12 to 47 months of age. In<br />
this subset, simultaneous administration of the single<br />
component vaccinations is preferred because of the<br />
increased risk of febrile convulsions with the MMRV<br />
vaccine. HPV vaccines are recommended in girls<br />
and boys from the age of 9. These vaccines confer<br />
protection against the oncological HPV serotypes<br />
(namely 6, 11, 16, 18), and help to prevent cervical,<br />
vaginal, vulval and anal cancers, and genital warts.<br />
HPV infection may also play a role in throat and<br />
penile cancers.<br />
Women planning to fall pregnant should receive the<br />
MMR vaccine (if immunity is insufficient), one or two<br />
months before falling pregnant, as this vaccine is<br />
not safe to administer during pregnancy. Ante-natal<br />
Rubella is particularly dangerous to the foetus – it<br />
may result in serious birth defects or even pregnancy<br />
loss. Inactivated influenza vaccine can safely be<br />
administered during pregnancy. This is particularly<br />
important as pregnant patients are at an increased<br />
risk of influenza-related complications.<br />
Patients also need to be made aware of the concept<br />
of herd immunity. Live-attenuated vaccinations are<br />
contra-indicated in severely immunocompromised<br />
patients. These patients rely on herd immunity to<br />
protect them from communicable diseases, but if<br />
vaccination rates are not maintained in a patient<br />
population, then these individuals are at risk. The antivaxxer<br />
movement has compromised herd immunity in<br />
certain areas, due to inadequate vaccination rates.<br />
The benefit of vaccination far outweighs the<br />
risks. <strong>Health</strong> care professionals should take every<br />
opportunity to vaccinate individuals, and vaccinations<br />
should not be delayed unless clear contra-indications<br />
exist. We need to do more to educate patients on<br />
the dangers of not vaccinating, in order to improve<br />
herd immunity and eradicate vaccine-preventable<br />
contagious diseases, and ultimately protect those<br />
individuals who are unable to receive vaccinations<br />
due to medical reasons.<br />
Inge Kriel: Oncology Care Physician, Milpark Breast Care Centre of Excellence. Correspondence: ingekriel84@gmail.com<br />
39 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
IZZY’S<br />
STORY<br />
Kyara Bergstrom<br />
The anti-vaxxer movement has upset me so much. People often get<br />
shocked at my reaction until they hear about my little girl Isabella, and<br />
then they understand why.<br />
Izzy has been ill since the day she was born. It<br />
was only at the age of 3 that she was diagnosed<br />
with Common Variable Immune Deficiency<br />
(CVID). Like most people I hadn’t heard about<br />
this. Let’s be honest - when most people think of<br />
immune system problems, we think of cancer and<br />
chemotherapy, or HIV. There are many more primary<br />
immune deficiencies. Think of the movie “Boy in the<br />
Bubble”.<br />
Izzy can’t fight infections on her own. She has a<br />
T-Cell defect, as well as a mannose binding lectin<br />
deficiency. One of the ways doctors diagnosed her is<br />
that she had no antibodies from her vaccines. I have<br />
vaccinated my kids with every single vaccine. I never<br />
used to believe in the flu vaccine until I saw my eldest<br />
get H1N1 (swine flu) when it was making the rounds.<br />
Have you ever seen your child crying and screaming<br />
in pain? You can’t comfort her because her body<br />
hurts so badly and she has a fever so high you don’t<br />
want to leave her for a minute in case she has a<br />
febrile seizure? Well that’s the year I started believing<br />
in the flu vaccine and now we all get vaccinated<br />
every year to protect ourselves, as well to protect Izzy<br />
as much as we can.<br />
Izzy relies on something called immunoglobins.<br />
When people donate blood, they only think of red<br />
blood cells and plasma for<br />
accident victims, surgery,<br />
cancer etc. What they don’t<br />
normally think about is the<br />
immunoglobins from these<br />
transfusions that are taken<br />
and given to people like Izzy.<br />
It takes a lot of transfusions<br />
to make one treatment<br />
and doesn’t rely on blood<br />
type. So I’m always on a<br />
Kyara Bergstrom<br />
campaign to get people to<br />
donate blood. She gets these immunoglobins every<br />
four weeks. Without this she will not be able to fight<br />
the infections like the rest of us. Even when she gets<br />
sick she’s placed on adult dosages of antibiotics and<br />
most of the time she has to be hospitalised when she’s<br />
sick.<br />
SO THIS BRINGS ME BACK TO VACCINES.<br />
PEOPLE OFTEN ASK ME “HOW IS MY<br />
UNVACCINATED CHILD DANGEROUS<br />
TO YOUR VACCINATED CHILD?”.<br />
I UNDERSTAND HOW THIS CAN BE<br />
CONFUSING AS MOST PEOPLE DON’T<br />
UNDERSTAND THE CONCEPT OF HERD<br />
IMMUNITY.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 40
FOCUS ON<br />
HERD<br />
IMMUNITY<br />
IF ENOUGH PEOPLE ARE VACCINATED,<br />
THEN THEY PROTECT THE PEOPLE THAT<br />
ARE UNABLE TO BE VACCINATED.<br />
IT’S NOT ONLY PEOPLE LIKE IZZY<br />
WHO RELY ON HERD IMMUNITY.<br />
ADULTS AND CHILDREN RECEIVING<br />
CANCER TREATMENT, PEOPLE ON<br />
IMMUNE SUPPRESSANTS FOR ORGAN<br />
TRANSPLANTS, HIV POSITIVE PATIENTS,<br />
AND PATIENTS WITH AUTO-IMMUNE<br />
DISEASES ALSO RELY ON HERD<br />
IMMUNITY. THEY DON’T HAVE A CHOICE<br />
AND THEY RELY ON OTHERS TO BE<br />
VACCINATED. HERD IMMUNITY ALSO<br />
PROTECTS THE YOUNG BABIES WHO ARE<br />
STILL TOO SMALL TO RECEIVE SOME OF<br />
THE VACCINES OR THE ELDERLY WHO<br />
CAN’T GET BOOSTERS ETC.<br />
Imagine a new born getting measles? If enough<br />
people are not vaccinated then the virus finds more<br />
ways to travel and infect the weak. If the virus mutates<br />
then even the vaccinated are more at risk. When<br />
there is another outbreak people like Izzy and other<br />
immune compromised people can’t receive boosters.<br />
They can’t protect themselves from the outbreaks.<br />
WITH SOCIAL MEDIA THE ANTI-VAXXER<br />
MOVEMENT HAS CAUSED MORE<br />
AND MORE OUTBREAKS. PEOPLE<br />
ARE BELIEVING MORE AND MORE<br />
“FACEBOOK MEDICAL PAGES” OR<br />
“FALSE LINKS AND STORIES”.<br />
I often urge people to do relevant research<br />
on more reputable sites. Think of journalistic<br />
sensationalism - everyone loves a dramatic story.<br />
You get people that love creating this drama and<br />
seeing how far their links go.<br />
PEOPLE BELIEVE THINGS THEY READ<br />
ESPECIALLY IF IT CONTAINS WORDS<br />
LIKE “SCIENTIFIC” OR “MEDICAL”, BUT<br />
THEY NEVER CHECK THE AUTHENTICITY<br />
OF THE DATA OR LINKS. I’VE HEARD<br />
AMAZING THINGS LIKE “POISONS IN<br />
VACCINES” AND “PHARMACEUTICAL<br />
GAIN”. THINK ABOUT IT; IF THE POISONS<br />
LINK HAD ANY TRUTH IN IT DO YOU<br />
THINK DOCTORS AND SCIENTISTS<br />
WOULD VACCINATE THEIR CHILDREN?<br />
The autism link that was published all those years<br />
ago has been proven to be false and the paper was<br />
removed from the medical journals after the doctor<br />
admitted to lying and he was stripped of his medical<br />
license. But the damage was done and parents<br />
believed it to be true and stopped vaccinating.<br />
Some natural doctors jumped on the bandwagon<br />
and many started selling their natural vaccines, books<br />
and remedies.<br />
People like my Izzy can’t fight these diseases and rely<br />
on the healthy population to be vaccinated. When<br />
there are outbreaks, I sit with so much fear and anger,<br />
praying my little girl will be safe.<br />
SHE NEEDS OTHER CHILDREN AND<br />
ADULTS TO BE VACCINATED TO KEEP<br />
HER, AND OTHERS LIKE HER, SAFE.<br />
Mrs. Kyara Bergstrom: Head of Research and Complementary <strong>Health</strong> at the Netcare Breast Care Centre of Excellence as well as<br />
C.O.O of The Pink Parasol Project (www.pinkparasol.co.za) Correspondence: Kyara.Bergstrom@netcare.co.za<br />
41 * SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
CHILDHOOD<br />
OBESITY<br />
AND WHY IT MATTERS WHAT<br />
CHILDREN EAT AT SCHOOL<br />
Francette Bekker<br />
School-aged children spend a large part of their day in the school<br />
environment and consume about a third of their daily energy<br />
requirements while at school.<br />
n an effort to manage and prevent childhood<br />
obesity, schools have become the focus of many<br />
nutrition interventions. Worldwide the obesity<br />
trends are increasing, and in <strong>South</strong> Africa one<br />
in almost every four school-aged children is either<br />
overweight or obese. The prediction is that these<br />
numbers will continue to rise at alarming rates. The<br />
risk is that an overweight or obese child will more<br />
often than not grow up to be an overweight or<br />
obese adult.<br />
OBESITY, AS WE KNOW, GOES HAND-<br />
IN-HAND WITH MANY LIFESTYLE<br />
ILLNESSES INCLUDING DIABETES,<br />
HEART DISEASE, AND CANCER. THE KEY<br />
IS TO TARGET CHILDREN WHILE THEY<br />
ARE STILL YOUNG AND DEVELOPING<br />
THEIR EATING HABITS.<br />
Registered dietitian, Francette Bekker was the<br />
principal researcher in a <strong>South</strong> <strong>African</strong> study about<br />
school tuck shops that was published in the Public<br />
<strong>Health</strong> Nutrition journal in May <strong>2017</strong>. The study<br />
compared the eating habits of children in a school<br />
with a healthy tuck shop to the eating habits of<br />
children in a school with a regular tuck shop. The<br />
healthy tuck shop offered a variety of items with<br />
no added sugar, low in salt, low in saturated fat<br />
and where possible high in fibre including slushies<br />
(fruit juice with crushed ice), iced lollies (frozen<br />
diluted fruit juice), small chicken sandwiches, sliced<br />
fruit, nuts, popcorn (air-popped) and oven-baked<br />
samoosas, while the regular tuck shop offered<br />
sweets, hamburgers, pies, pizza, potato crisps and<br />
carbonated cold drinks. The study had a number<br />
of interesting findings.<br />
Children in a school with a healthy tuck shop<br />
brought significantly more healthy items to school in<br />
their lunchboxes (such as fruit and water) compared<br />
to children in a school with a regular tuck shop.<br />
In the school with the healthy tuck shop children<br />
also had a more positive attitude towards fruits<br />
and vegetables. The younger children were more<br />
favorable towards the concept of having a healthy<br />
tuck shop at school, but despite that, children from<br />
all age groups supported and bought items at the<br />
healthy tuck shop.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong> * 42
FOCUS ON<br />
LUNCHBOXES<br />
When asked to make suggestions children had<br />
many ideas about what else they would like to have<br />
available at their healthy tuck shop - including <strong>South</strong><br />
<strong>African</strong> favorites like biltong and braaivleis.<br />
Overall the results suggested that children’s eating<br />
behaviours at school can be positively influenced<br />
when they are exposed to healthy food and<br />
beverages from a young age. But unfortunately, the<br />
researchers had another unexpected yet fascinating<br />
finding. Children in the school with a healthy tuck shop<br />
did not only bring more healthy items to school in their<br />
lunchboxes but compared to children in a school with<br />
a regular tuck shop, their lunchboxes also contained<br />
significantly more unhealthy items (like sweets and<br />
potato crisps).<br />
This was possible because they could not buy these<br />
items while at school. So, in this case, the many positive<br />
influences of the healthy tuck shop was counteracted<br />
by additional unhealthy items in lunchboxes<br />
brought from home.<br />
HAVING A SCHOOL FOOD POLICY IN<br />
PLACE THAT ENCOURAGES CHILDREN<br />
TO BRING HEALTHY FOOD TO SCHOOL IS<br />
AN OPTION, BUT THAT IS NOT THE ONLY<br />
ANSWER. PARENTS WHO ARE PACKING<br />
LUNCHBOXES, BUYING GROCERIES<br />
AND PREPARING MEALS AT HOME ARE<br />
CHILDREN’S ROLE MODELS, & THEY NEED<br />
TO BECOME MORE INVOLVED IN THE<br />
FIGHT AGAINST CHILDHOOD OBESITY.<br />
Parents must realise the importance of providing<br />
healthy food and beverages and know the risks<br />
involved of having an overweight or obese child.<br />
ALTHOUGH CHILDREN LIKE TO<br />
HAVE A CHOICE IN WHAT THEY EAT,<br />
MANY CHILDREN IN BEKKER’S STUDY<br />
PREFERRED A BALANCE AND TREATS<br />
PER OCCASION ONLY, BECAUSE THEY<br />
WERE SCARED OF BECOMING FAT. BY<br />
LIMITING THE VARIETY ON DISPLAY IN<br />
TUCK SHOPS AND MARKETING HEALTHY<br />
FOOD FOR SALE, CHILDREN MAY BE<br />
ENCOURAGED TO MAKE HEALTHIER<br />
FOOD CHOICES.<br />
The same applies at<br />
home – when there is a<br />
wide variety available,<br />
children tend to make<br />
unhealthy choices.<br />
Involve children and<br />
teach them about<br />
food, listen to their<br />
suggestions and then<br />
also guide them to<br />
make better food and<br />
beverage choices at<br />
school and home.<br />
Having healthy tuck shops at schools may not be<br />
the full solution to the obesity epidemic, but it is an<br />
excellent place to start.<br />
PARENTS AND SCHOOLS WHO ARE SEEKING ADVICE CAN USE<br />
THE ASSOCIATION FOR DIETETICS IN SOUTH AFRICA (ADSA)<br />
WEBSITE TO SEARCH FOR A REGISTERED DIETITIAN IN THEIR<br />
AREA. THERE ARE ALSO ORGANISATIONS THAT GIVE GUIDANCE<br />
AND HAVE ONLINE TOOLS FOR SETTING UP HEALTHY TUCK<br />
SHOPS AT SCHOOLS. THESE INCLUDE THE DISCOVERY VITALITY<br />
SCHOOLS PROGRAMME HEALTHY TUCK SHOP GUIDELINES &<br />
THE WOOLWORTHS HEALTHY TUCK SHOP GUIDE.<br />
Francette Bekker: Registered Dietitian (SA). Correspondence: Please contact the relevant sub-editor as well as cc the<br />
Editor-in-Chief for more information.<br />
43 *<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
PROGNOSTIC &<br />
ONCOLOGY<br />
PREDICTIVE<br />
MARKERS IN<br />
BREAST CANCER<br />
Georgia Demetriou<br />
Biomarkers can be determined in numerous<br />
ways, some are identified in easily obtained<br />
body fluids such as plasma, serum, and urine,<br />
but many biomarkers can only be identified<br />
on tumour tissue from immunohistochemical stains,<br />
DNA and RNA. In many cases biomarkers are<br />
initially identified without being placed in either the<br />
prognostic or predictive biomarker category, over<br />
time the prognostic value of the biomarker may<br />
become apparent and in many cases, therapeutic<br />
options are subsequently developed to target the<br />
prognostic marker making it a predictive marker too.<br />
A predictive marker may be able to define the<br />
benefit of a therapeutic intervention or its potential<br />
futility, allowing for far more personalized and patientspecific<br />
interventions. Some serum biomarkers can be<br />
used to monitor treatment response. The utility of a<br />
particular biomarker may be particular to a single<br />
tumour site or be of value in more than one cancer.<br />
OESTROGEN(ER) AND PROGESTERONE<br />
(PR) RECEPTOR EXPRESSION IS AN<br />
INDEPENDENT PROGNOSTIC FACTOR<br />
IN BREAST CANCER. PATIENTS WITH ER<br />
AND/OR PR POSITIVE TUMOURS HAVE<br />
A BETTER SURVIVAL THAN HORMONE<br />
RECEPTOR NEGATIVE TUMOURS. THE FIVE<br />
YEAR SURVIVAL (ALL STAGES) OF BREAST<br />
CANCER IS IN THE REGION OF 83% IN THE<br />
ER+/PR+ GROUP VERSUS 69% IN PATIENTS<br />
WITH “DOUBLE NEGATIVE” DISEASE.<br />
A high cellular expression of<br />
ER and PR predicts for benefit<br />
from endocrine blockade in<br />
the adjuvant and metastatic<br />
setting. Tumour hormone<br />
receptors can change during<br />
the course of disease with the<br />
ER status of metastatic disease<br />
differing from the primary in<br />
Georgia Demetriou 20% of cases. The PR expression<br />
can be lost in up to 40% of metastatic lesions when<br />
compared to the primary lesion. This information<br />
has resulted in a change in practice where the<br />
reassessment of a metastatic lesions hormone<br />
receptors by repeated biopsy is advised on the<br />
diagnosis of a metastasis if the lesion is amenable to<br />
sampling without creating undue risk from procedural<br />
complications, in some cases, it may influence<br />
treatment planning.<br />
Her2 gene amplification leads to overexpression of<br />
its receptor on the cell membrane. Over expression<br />
of Her2 results in increased proliferation, angiogenesis<br />
and inhibition of apoptosis. Overall Her2 positive<br />
tumours are more aggressive and have a worse<br />
prognosis compared to those that are negative.<br />
ASSESSMENT OF HER2 STATUS IS<br />
ESSENTIAL IN ALL BREAST CANCER<br />
PATIENTS TO DETERMINE PATIENT<br />
ELIGIBILITY FOR HER2-TARGETED<br />
THERAPY.<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong> * 44
FOCUS ON<br />
HER2<br />
HER2 STATUS PREDICTS OUTCOMES<br />
IN BREAST CANCER, INCLUDING<br />
A RESPONSE TO TRASTUZUMAB,<br />
PERTUZUMAB, AND TDM-1, IT ALSO<br />
PREDICTS THE RESPONSE TO VARIOUS<br />
TYROSINE KINASE INHIBITORS, TAXANE<br />
AND ANTHRACYCLINE CHEMOTHERAPY<br />
AND A RELATIVE RESISTANCE TO<br />
TAMOXIFEN.<br />
Four phase III clinical trials enrolled more than 13 000<br />
pts, these studies (HERA, Combined B31 & N9831<br />
analysis and the BCIRG006) established the benefit<br />
of a year’s trastuzumab in the adjuvant treatment<br />
of Her2 positive breast cancer. To date studies of a<br />
shorter trastuzumab duration have been unable to<br />
demonstrate noninferiority when compared to a<br />
year’s treatment.<br />
Lapatinib is a small molecule tyrosine kinase inhibitor<br />
that, like trastuzumab, blocks the activity of the Her2<br />
protein, but it does so by a different mechanism.<br />
Lapatinib binds to the intracellular part of the Her2<br />
protein and is a potent, reversible inhibitor of ErbB1<br />
and ErbB2, which are members of a receptor tyrosine<br />
kinase family.<br />
Like ER and PR expression Her2 expression can change<br />
over time and can vary between lesions requiring<br />
repeat biopsy when metastasis occurs if feasible or<br />
if there is a progression of the disease. Both primary<br />
and secondary resistance to trastuzumab can occur<br />
with the expansion of tyrosine kinase inhibitors in the<br />
second line metastatic setting and beyond.<br />
Ki 67 a nonhistone protein which is universally<br />
expressed among proliferating cells is expressed in G1,<br />
S and G2 phases of the cell cycle with a peak during<br />
mitosis. Ki 67 usually has a low proliferative activity in<br />
ER-positive tumours, with high levels of ki 67 at baseline<br />
indicating an aggressive tumour.<br />
A high pre-treatment score is associated with<br />
a good chance of achieving a complete<br />
pathological response to chemotherapy and<br />
thus paradoxically a good long-term outcome.<br />
Post neoadjuvant chemotherapy measurement<br />
of ki 67 is a strong predictor of recurrence-free and<br />
overall survival.<br />
Cyclin D1 is localized on chromosome 11q23 and<br />
has been identified in 20% of breast cancers, it<br />
has a strong correlation with ER and PR expression<br />
levels and has predictive value in hormone<br />
receptor positive patients as its co-amplification<br />
and overexpression is a predictor of inadequate<br />
response to anti-estrogen treatments.<br />
THE ONCOLOGICAL AGE OF<br />
PERSONALIZED AND MOLECULAR<br />
MEDICINE HAS MOVED FROM<br />
THE LAB TO OUR CLINICS AND IS<br />
RELEVANT IN EVERYDAY PRACTICE.<br />
STRONG PROGNOSTIC AND<br />
PREDICTIVE MARKERS HAVE<br />
IMPROVED PATIENT OUTCOMES AND<br />
WILL HOPEFULLY CONTINUE TO IN<br />
THE FUTURE.<br />
DEFINITIONS:<br />
BIOMARKER<br />
A CHARACTERISTIC THAT CAN BE OBJECTIVELY<br />
MEASURED AND EVALUATED IN A PATHOLOGIC<br />
PROCESS OR A TUMOUR<br />
PROGNOSTIC MARKER<br />
A BIOMARKER THAT PROVIDES INFORMATION ABOUT<br />
A PATIENT’S OVERALL OUTCOME REGARDLESS OF THE<br />
TREATMENT A PATIENT RECEIVES<br />
PREDICTIVE MARKER<br />
A BIOMARKER THAT PROVIDES INFORMATION ABOUT<br />
THE THERAPEUTIC EFFECT OF AN INTERVENTION<br />
Georgia Demetriou: Senior Consultant in the Division of Medical Oncology at the University of Witwatersrand Faculty of <strong>Health</strong><br />
Sciences and Charlotte Maxeke Johannesburg Academic Hospital since 2004. She is Head of a General Medicine Undergraduate<br />
Academic teaching unit for the Department of Internal Medicine at Charlotte Maxeke Johannesburg Academic Hospital.<br />
Correspondence: georgiademetriou@hotmail.com<br />
45 *<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 2 <strong>2017</strong>
FOCUS ON<br />
SOUTH AFRICA’S<br />
CULTURAL OBSESSION WITH FOOD &<br />
THE PSCYHOLOGY OF WEIGHT LOSS<br />
HOW GASTRIC BYPASS PATIENTS<br />
‘LEARN TO EAT AGAIN’<br />
Martina Nicholson<br />
Obesity is a growing concern in <strong>South</strong> Africa, particularly because<br />
of the lifestyle diseases associated with it, including type 2 diabetes,<br />
hypertension and heart disease.<br />
SURGERY, OBESITY & METABOLISM<br />
Gastric bypass surgery is an increasingly<br />
popular treatment option for appropriate<br />
patients, however surgery alone cannot<br />
address the unhealthy relationship with<br />
food that frequently leads to obesity.<br />
“OFTEN PEOPLE REWARD OR COMFORT<br />
THEMSELVES WITH FOOD, WHICH IS<br />
EATING FOR PSYCHOLOGICAL RATHER<br />
THAN NUTRITIONAL REASONS, AND,<br />
OVER TIME, THIS CAN BECOME DEEPLY<br />
INGRAINED AND MAY LEAD TO OBESITY,”<br />
EXPLAINS CHARLENE MCINTOSH,<br />
ONE OF THE PSYCHOLOGISTS IN THE<br />
MULTIDISCIPLINARY TEAM SUPPORTING<br />
GASTRIC BYPASS PATIENTS OF GENERAL<br />
SURGEON, DR GERT DU TOIT, AND HIS<br />
SURGICAL PARTNER DR IVOR FUNNELL,<br />
WHO HEAD UP THE BARIATRIC SURGERY<br />
CENTRE AT NETCARE ST AUGUSTINE’S<br />
HOSPITAL.”<br />
“Another aspect that appears to be driving obesity<br />
is the central role of food in <strong>South</strong> <strong>African</strong> culture, by<br />
which I mean that many of our social interactions<br />
tend to revolve around eating,” she explains.<br />
“We often meet friends and family for a meal, tea<br />
and cake, shisinyama or a braai. For people who are<br />
grappling with their weight, this can make it even<br />
harder for them to exercise self-control, particularly if<br />
they feel social pressure to eat,” says McIntosh.<br />
Dr Du Toit, who specialises in complex digestive<br />
laparoscopic procedures, says that gastric bypass<br />
surgery is not to be undertaken lightly and is not<br />
appropriate for all patients with obesity and related<br />
conditions.<br />
“We are committed to helping patients achieve<br />
positive health outcomes, and there is a growing<br />
body of evidence to suggest that conditions such<br />
as type 2 diabetes and hypertension can be well<br />
controlled, if not fully alleviated, with gastric bypass<br />
surgery and behavioural change,” Dr Du Toit notes.<br />
In line with the protocols of the <strong>South</strong> <strong>African</strong> Society<br />
for Surgery, Obesity and Metabolism (SASSO),<br />
prospective patients must be assessed for suitability<br />
and supported through the surgery and afterwards by<br />
a multidisciplinary team of healthcare professionals.<br />
“Patients must be dedicated and committed to<br />
making a lifelong change, otherwise the surgical<br />
intervention will be far less likely to help the individual<br />
achieve better health over the long term. For<br />
this reason, it is sometimes advisable for patients<br />
to prepare for a few additional months to make<br />
absolutely certain that they are ready for the<br />
significant lifestyle changes to ensure that they get<br />
the best out of the treatment,” explains Dr Du Toit.<br />
Dr Du Toit likens the preparation for gastric bypass<br />
surgery to that of climbing a mountain. “If you consider<br />
people who climb Mount Everest, it is the ones who<br />
never look back who are most likely to make it to the<br />
summit. Our team needs to ensure that the surgical<br />
SOUTH AFRICAN PSYCHIATRY ISSUE 2 <strong>2017</strong> * 46
FOCUS ON<br />
candidates have a similar mindset and commitment<br />
before the gastric bypass is performed.”<br />
A vital aspect of preparation for the surgery is dealing<br />
with the emotional aspects, as McIntosh explains: “The<br />
role of the psychologist is to identify and address<br />
underlying emotional trauma that may be at the<br />
root of some people’s compulsion to eat. This is a vital<br />
aspect of the holistic treatment for patients undergoing<br />
gastric bypass surgery, because the operation can<br />
change the body but the person’s mindset also needs<br />
to change to achieve lasting outcomes.”<br />
“WE EMPHASISE THAT THERE IS A<br />
DISTINCTION BETWEEN EATING<br />
BECAUSE YOU ARE HUNGRY AND<br />
EATING FOR PSYCHOLOGICAL OR<br />
SOCIAL REASONS. PEOPLE NEED TO<br />
REDEFINE THEIR RELATIONSHIP WITH<br />
FOOD, AND IN THE CASE OF OBESE<br />
PATIENTS WE ESSENTIALLY HAVE TO<br />
TEACH THEM TO EAT AGAIN.”<br />
Addressing the social pressures around eating often<br />
requires the individual’s support base, including family<br />
and friends, to develop greater awareness. “Instead of<br />
organising time together around food, as in ‘let’s meet<br />
for lunch’, it is a good idea to sensitise the person’s social<br />
circle to rather meet for a walk or other activities that do<br />
not centre around eating,” she advises.<br />
This is one of the messages conveyed in the monthly<br />
meeting of the support group for people who have<br />
either had or are considering gastric bypass surgery,<br />
hosted by dietitian Mandy Read, who is also part of<br />
the multidisciplinary team at the bariatric surgery<br />
centre. The meetings are also open to the family and<br />
friends supporting patients through their journey.<br />
“A key aspect of changing people’s emotional<br />
reliance on food is replacing comfort eating or reward<br />
eating with another pleasurable activity, such as<br />
going for a massage, having a relaxing bubble bath<br />
or learning to play a musical instrument. Interestingly,<br />
we have found that people who replace emotional<br />
eating with a creative outlet, such as painting,<br />
photography, music or gardening, tend to have better<br />
outcomes in general,” McIntosh observes.<br />
“Perhaps the most important factor is for the person to<br />
realise that they can shape their future and have real<br />
belief that their lives can be different. If a person has<br />
been morbidly obese for many years, sadly they often<br />
become used to sitting at home and feeling isolated,<br />
and cannot imagine a life beyond that.”<br />
“Imagine clothes shopping, and being so limited in<br />
your choice because you are trying to find something<br />
that is large enough to fit you, rather than shopping for<br />
clothing that makes you look and feel good. We try to<br />
help people realise that there is a life beyond obesity<br />
and help them to get to the stage where they can<br />
get full enjoyment out of life without an overreliance<br />
on food,” she adds.<br />
According to McIntosh people who have lost a<br />
lot of weight may have some difficulty reconciling<br />
the changes in their bodies with the way they see<br />
themselves. “Some patients have managed to get<br />
down to a healthy weight but will still turn sideways<br />
to go through doors as they had to when they were<br />
morbidly obese. Often there is a process of re-building<br />
a person’s self-esteem so that they can make the best<br />
of the physical transformation they have achieved,”<br />
she concludes.<br />
CENTRES OF EXCELLENCE FOR METABOLIC<br />
MEDICINE AND SURGERY<br />
There are currently five centres of excellence for<br />
metabolic medicine and surgery at Netcare hospitals,<br />
offering patients access to specialised bariatric<br />
surgery, including gastric bypass procedures.<br />
These centres of excellence are located at Netcare<br />
Sunward Park Hospital in Boksburg, Netcare St<br />
Augustine’s Hospital in Durban, Netcare Greenacres<br />
Hospital in Port Elizabeth, Netcare N1 City Hospital in<br />
Cape Town, and Netcare Waterfall City Hospital in<br />
Midrand, Gauteng. The centre at Netcare Waterfall<br />
City Hospital is the only internationally accredited<br />
centre for the treatment of bariatric and metabolic<br />
conditions in <strong>South</strong> Africa, and is the principal centre<br />
for the four other locally accredited centres of<br />
excellence located at Netcare hospitals.<br />
The dedicated multi-disciplinary teams at these<br />
centres are comprised of surgeons, endocrinologists,<br />
psychiatrists, psychologists and dietitians, among<br />
others, in line with the protocols advocated by<br />
the <strong>South</strong> <strong>African</strong> Society for Surgery, Obesity and<br />
Metabolism (SASSO), which is chaired by endocrinologist,<br />
Professor Tess van der Merwe. As director of the Centres<br />
of Excellence for Metabolic Medicine and Surgery of<br />
<strong>South</strong> Africa (CEMMS)(SA), Prof van der Merwe oversees<br />
the work of the centres of excellence, including those<br />
based at Netcare hospitals.<br />
The centres adhere to international practices to<br />
create a safe environment and to support obese<br />
patients with empathy and care. To comply with<br />
international standards, a database with statistics on<br />
each patient is maintained. Strict rules and regulations<br />
with regard to patients’ dietary environment, as<br />
well as care in ICU and wards are followed. Training<br />
facilities with specialised technology and equipment<br />
are also incorporated in the centres.<br />
Martina Nicholson Associates (MNA): on behalf of Netcare St Augustine’s Hospital Correspondence: martina@mnapr.co.za,<br />
graeme@mnapr.co.za<br />
47 *<br />
SOUTH AFRICAN WOMEN'S HEALTH ISSUE 1 <strong>2017</strong>
40 SOUTH AFRICAN PSYCHIATRY ISSUE 4 2015<br />
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