21.03.2018 Views

ADC LINKERS

All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilities the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC.

All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilities the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC.

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ANTIBODY-DRUG<br />

CONJUGATES<br />

www.creative-biolabs.com/adc<br />

<strong>ADC</strong> <strong>LINKERS</strong><br />

All chemical linkers are of >95% purity and they are the<br />

basic building blocks for a successful <strong>ADC</strong>. Linkers<br />

facilities the conjugation of <strong>ADC</strong> toxins to antibodies<br />

and in the meantime, they also dictate the release<br />

mechanism of an <strong>ADC</strong>.<br />

PODOPHYLLOTOXIN<br />

Creative Biolabs offers highly potent toxins and toxin<br />

derivatives targeting a variety of cellular pathways, including<br />

microtubule assemble and dynamics (microtubule toxins),<br />

DNA biochemistry and structure (DNA toxins), and gene<br />

transcription (transcription toxins) … for antibody-drug<br />

conjugate (<strong>ADC</strong>) development.<br />

POLYKETOMYCIN<br />

<strong>ADC</strong> toxins target crucial intracellular pathways to induce<br />

cell death and they can be over 1000-fold more potent than<br />

chemo therapeutic agents. Creative Biolabs carriers a large<br />

selection of <strong>ADC</strong> toxins ranging from common auristatins,<br />

maytansinoids, calicheamicins to more innovative toxins such<br />

as amatoxins….<br />

CREATIVE BIOLABS<br />

Creative Biolabs is committed to providing high-quality<br />

services to promote the development of <strong>ADC</strong> and other<br />

innovative targeted protein therapeutic agents.

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