Enzyme Replacement Therapy Market Opportunity Analysis, 2018-2026
Increasing collaborations amongst key companies to fast-track the development of enzymes for replacement is expected to boost growth of the enzyme replacement therapy market size.
Increasing collaborations amongst key companies to fast-track the development of enzymes for replacement is expected to boost growth of the enzyme replacement therapy market size.
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<strong>Enzyme</strong> <strong>Replacement</strong> <strong>Therapy</strong> <strong>Market</strong><br />
GLOBAL INDUSTRY INSIGHTS, TRENDS,<br />
OUTLOOK, AND OPPORTUNITY ANALYSIS, <strong>2018</strong>-<br />
<strong>2026</strong><br />
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REPORT DESCRIPTION<br />
<strong>Enzyme</strong> <strong>Replacement</strong> <strong>Therapy</strong> <strong>Market</strong> – Overview<br />
<strong>Enzyme</strong> replacement therapy involves intravenous administration of enzymes in order to correct the deficiency of<br />
enzymes that causes a specific disease condition called lysosomal storage disease. <strong>Enzyme</strong> replacement therapy is<br />
used in Fabry Disease, Gaucher disease, lysosomal acid lipase deficiency, mucopolysaccharidosis, Hunter<br />
syndrome, and Pompe disease. <strong>Enzyme</strong>s are obtained from sources such as human cells, animal cells, and<br />
recombinant DNA technology. <strong>Enzyme</strong> replacement, although does not provide permanent cure, helps prevents<br />
permanent damage to the body caused due to deficiency of a specific enzyme. Treatment consists of weekly or<br />
monthly doses depending upon the disease. For instance, in order to address enzyme deficiency in Gaucher<br />
disease, modified version of glucocerebrosidase is administered intravenously every two weeks. <strong>Enzyme</strong><br />
replacement is associated with fewer side effects than other treatment methods. However, enzyme replacement<br />
therapy may be inconvenient for some patients such as children and geriatric population due to intravenous<br />
administration. It may result in local infusion reaction or hypersensitive reactions in the form of local rash, fever,<br />
edema, bronchospasm or hypotension.<br />
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REPORT DESCRIPTION<br />
<strong>Enzyme</strong> <strong>Replacement</strong> <strong>Therapy</strong> <strong>Market</strong> Taxonomy:<br />
On the basis of enzyme type, the global enzyme replacement therapy market is segmented into -:<br />
Agalsidase Beta<br />
Velaglucerase Alfa<br />
Imiglucerase<br />
Taliglucerase<br />
Alglucosidase Alfa<br />
Laronidase<br />
Idursulfase<br />
Galsulfase<br />
Pegademase<br />
Others<br />
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REPORT DESCRIPTION<br />
<strong>Enzyme</strong> <strong>Replacement</strong> <strong>Therapy</strong> <strong>Market</strong> Taxonomy:<br />
On the basis of indication, the global enzyme replacement therapy market is segmented into -:<br />
Fabry Disease<br />
Gaucher Disease<br />
Pompe Disease<br />
Scheie Syndrome<br />
Hunter Disease<br />
Maroteaux-Lamy Syndrome<br />
Others<br />
On the basis of end user, the global enzyme replacement therapy market is segmented into -:<br />
Hospitals<br />
Clinics<br />
Home care setting<br />
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REPORT DESCRIPTION<br />
<strong>Enzyme</strong> <strong>Replacement</strong> <strong>Therapy</strong> <strong>Market</strong> Taxonomy:<br />
On the basis of geography, the global enzyme replacement therapy market is segmented into:<br />
North America<br />
Latin America<br />
Europe<br />
Asia Pacific<br />
Middle East<br />
Africa<br />
On the basis of geography, the global enzyme replacement therapy market is segmented into North<br />
America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to<br />
lead the market during forecast period, followed by Europe. According to study published in journal<br />
Hematology, in March 2017, incidence of Gaucher Disease in the general population varied from<br />
0.39 to 5.80 per 100?000, and its prevalence varied from 0.70 to 1.75 per 100?000. Ease in access<br />
and government support for research and development is expected to aid growth of the enzyme<br />
replacement therapy market.<br />
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REPORT DESCRIPTION<br />
<strong>Enzyme</strong> <strong>Replacement</strong> <strong>Therapy</strong> <strong>Market</strong>: Key Players<br />
Major players involved in the global enzyme replacement therapy market include:<br />
Shire plc<br />
Amicus Therapeutics<br />
Genzyme Corporation<br />
Pfizer Inc.<br />
BioMarin Pharmaceutical, Inc.<br />
Sigma-Tau Pharmaceuticals Inc.<br />
Essential Pharmaceuticals Limited<br />
Merck Kga<br />
AbbVie Inc.<br />
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